## Sat Jan  4 00:28:27 2025
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA629394/SRR11734600/SRR11734600_p_cluster_rep_seq.fasta --output PRJNA629394_SRR11734600 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k59_178674_1	502025.Hoch_3974	1e-32	130.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YUSA@29|Myxococcales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_60987_1	1192034.CAP_7382	2.02e-12	67.8	COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,42RM6@68525|delta/epsilon subdivisions,2WNFG@28221|Deltaproteobacteria,2Z02I@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_31739_1	1185876.BN8_05652	2.23e-17	85.9	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_84474_1	1265505.ATUG01000002_gene1827	3.45e-38	136.0	COG0535@1|root,COG0535@2|Bacteria,1N6IN@1224|Proteobacteria,43BE9@68525|delta/epsilon subdivisions,2X6SR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_19412_1	349161.Dred_0286	1.43e-19	90.1	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,2617C@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_107935_1	281687.CJA35933	4.34e-56	194.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,4150V@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14090_1	266835.14022169	2.17e-07	58.5	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U139@28211|Alphaproteobacteria,43IVT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_96613_1	1121285.AUFK01000019_gene101	2.16e-11	63.5	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,1I3G4@117743|Flavobacteriia,3ZRPB@59732|Chryseobacterium	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_84478_1	401053.AciPR4_1398	2.51e-26	117.0	COG1305@1|root,COG1305@2|Bacteria,3Y3A2@57723|Acidobacteria,2JISQ@204432|Acidobacteriia	204432|Acidobacteriia	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
k59_55094_1	448385.sce5128	4.99e-15	77.4	COG1360@1|root,COG1360@2|Bacteria,1PDU8@1224|Proteobacteria,42RAZ@68525|delta/epsilon subdivisions,2WMY4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_8167_1	880073.Calab_3453	1.06e-26	120.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_72659_2	1196323.ALKF01000140_gene3520	8.62e-11	65.9	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HA85@91061|Bacilli,26QW0@186822|Paenibacillaceae	91061|Bacilli	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH
k59_43236_1	1499967.BAYZ01000071_gene1998	9.89e-20	93.2	COG1674@1|root,COG5635@1|root,COG1674@2|Bacteria,COG5635@2|Bacteria,2NR8B@2323|unclassified Bacteria	2|Bacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NACHT,TIR_2,TPR_12,TPR_8
k59_172199_2	7897.ENSLACP00000014527	9.78e-42	151.0	KOG1075@1|root,KOG1075@2759|Eukaryota,38Y7H@33154|Opisthokonta,3C5TR@33208|Metazoa,3DG8G@33213|Bilateria	33208|Metazoa	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119772_1	29730.Gorai.013G108100.1	2.23e-19	80.1	2D08W@1|root,2SD7U@2759|Eukaryota,37XFR@33090|Viridiplantae,3GMII@35493|Streptophyta	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface	psbM	-	-	ko:K02714	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbM
k59_96621_2	35754.JNYJ01000025_gene8877	7.14e-23	97.4	COG0279@1|root,COG0279@2|Bacteria,2IIGW@201174|Actinobacteria,4DCS3@85008|Micromonosporales	201174|Actinobacteria	G	Phosphoheptose isomerase	gmhA	-	2.7.7.71,5.3.1.28	ko:K03271,ko:K15669	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769,R09772	RC00002,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_66986_1	43151.ADAC010723-PA	2.54e-101	320.0	COG1007@1|root,KOG4668@2759|Eukaryota,38F5W@33154|Opisthokonta,3BEVW@33208|Metazoa,3CTS4@33213|Bilateria,4203F@6656|Arthropoda,3SM8H@50557|Insecta,451X3@7147|Diptera,45BQK@7148|Nematocera	33208|Metazoa	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	ND5	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009636,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010257,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0046677,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0070482,GO:0071704,GO:0071840,GO:0072521,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:1901135,GO:1901360,GO:1901564,GO:1901698,GO:1901700,GO:1902494,GO:1990204	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
k59_72667_1	1118059.CAHC01000005_gene1016	5.71e-59	204.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_72667_2	226186.BT_3649	3.74e-34	129.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,2FPXY@200643|Bacteroidia,4AMRA@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 9.26	tldD3	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_178715_1	861299.J421_3401	5.98e-64	220.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_119796_1	1111730.ATTM01000012_gene2748	1.04e-08	50.4	2EK6X@1|root,33DXA@2|Bacteria,4NY6H@976|Bacteroidetes,1I6BA@117743|Flavobacteriia,2NXVQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_178724_1	552811.Dehly_1440	4.58e-108	328.0	COG3666@1|root,COG3666@2|Bacteria,2G998@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_178728_1	498761.HM1_1605	6.7e-43	155.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_119803_1	7029.ACYPI001208-PA	1.62e-15	81.6	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa,3DKI7@33213|Bilateria,422A5@6656|Arthropoda,3SQP0@50557|Insecta	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_31802_1	891968.Anamo_0408	5.48e-112	347.0	COG0021@1|root,COG0021@2|Bacteria,3TAH4@508458|Synergistetes	508458|Synergistetes	H	Belongs to the transketolase family	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_119806_1	710685.MycrhN_5026	1.69e-14	74.7	2EC6I@1|root,33651@2|Bacteria,2IGU7@201174|Actinobacteria,2390H@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
k59_166941_1	688270.Celal_1141	3.64e-28	116.0	COG1541@1|root,COG1541@2|Bacteria,4NFFT@976|Bacteroidetes,1HZKR@117743|Flavobacteriia,1FA2C@104264|Cellulophaga	976|Bacteroidetes	H	COG1541 Coenzyme F390 synthetase	capK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_119819_1	1122605.KB893646_gene115	7.78e-79	258.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQ80@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
k59_37820_1	1379698.RBG1_1C00001G0584	1.26e-36	143.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
k59_119828_2	880073.Calab_3298	4.28e-12	68.9	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
k59_184106_1	40148.OGLUM01G48980.1	8.16e-37	129.0	COG0445@1|root,KOG2311@2759|Eukaryota,38ACW@33090|Viridiplantae,3GYK3@35493|Streptophyta,3MB61@4447|Liliopsida,3IURC@38820|Poales	35493|Streptophyta	T	GidA associated domain 3	-	-	-	-	-	-	-	-	-	-	-	-	GIDA,GIDA_assoc,LRRNT_2,LRR_8,Pkinase
k59_78656_1	290315.Clim_0852	3.77e-15	82.0	COG1009@1|root,COG1009@2|Bacteria,1FDAG@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_43270_2	1288484.APCS01000031_gene2346	2.48e-99	318.0	COG5362@1|root,COG5362@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
k59_19475_1	747365.Thena_0280	5.43e-05	46.2	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,42H66@68295|Thermoanaerobacterales	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
k59_19475_2	349161.Dred_1689	1.69e-48	161.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,261GR@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_143216_1	1121396.KB892901_gene2187	4.3e-73	239.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_2258_2	86416.Clopa_0709	1.34e-17	85.9	COG0791@1|root,COG3772@1|root,COG0791@2|Bacteria,COG3772@2|Bacteria,1VG3D@1239|Firmicutes,24FAD@186801|Clostridia,36NX0@31979|Clostridiaceae	186801|Clostridia	M	Phage lysozyme	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CW_binding_1,Phage_lysozyme,VCBS
k59_107999_1	400682.PAC_15711609	4.81e-26	114.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3C1BS@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_49342_1	7029.ACYPI44692-PA	2.58e-35	137.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39MYT@33154|Opisthokonta,3CPI0@33208|Metazoa,3E5NZ@33213|Bilateria	2759|Eukaryota	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	ko:K14297	ko03013,ko05164,map03013,map05164	M00427	-	-	ko00000,ko00001,ko00002,ko03019,ko03036	1.I.1	-	-	RVT_1,RVT_3,zf-RVT
k59_49342_2	8090.ENSORLP00000022546	1.81e-10	63.5	2CN11@1|root,2QT83@2759|Eukaryota,38D3X@33154|Opisthokonta,3BDRF@33208|Metazoa,3CX54@33213|Bilateria,482YQ@7711|Chordata,494V4@7742|Vertebrata,4A5IQ@7898|Actinopterygii	33208|Metazoa	S	Family with sequence similarity 200, member A	FAM200A	-	-	-	-	-	-	-	-	-	-	-	-
k59_172227_1	56780.SYN_00977	1.54e-17	87.8	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1MU9B@1224|Proteobacteria,42R36@68525|delta/epsilon subdivisions,2WMNT@28221|Deltaproteobacteria,2MSIX@213462|Syntrophobacterales	28221|Deltaproteobacteria	NT	Single cache domain 3	mcp40H-7	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_3,sCache_3_2,sCache_3_3
k59_26195_1	517418.Ctha_0230	1.29e-12	71.2	COG2706@1|root,COG5184@1|root,COG2706@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_5,CHU_C,Cadherin-like,VCBS
k59_37854_1	411462.DORLON_03017	2.76e-48	166.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,27UV6@189330|Dorea	186801|Clostridia	C	Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_49353_1	631362.Thi970DRAFT_02897	8.52e-40	139.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
k59_133130_1	313606.M23134_07874	2.6e-19	97.8	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin-like,DUF11,OmpA,SdrD_B,SprB
k59_185925_1	335541.Swol_2463	2.81e-22	99.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_27757_1	7091.BGIBMGA006564-TA	1.16e-22	94.7	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_4164_1	314285.KT71_00585	3.84e-10	66.2	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1J5U1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	COG1419 Flagellar GTP-binding protein	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_174035_1	1121033.AUCF01000004_gene5065	2.81e-85	270.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,2TTA3@28211|Alphaproteobacteria,2JRM6@204441|Rhodospirillales	204441|Rhodospirillales	K	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF3335
k59_174035_2	1121403.AUCV01000013_gene4008	3.8e-42	151.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,43CAR@68525|delta/epsilon subdivisions,2X7M8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_133134_1	1121451.DESAM_10206	1.29e-38	147.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_62583_1	33876.JNXY01000018_gene7774	2.58e-27	100.0	COG2314@1|root,COG2314@2|Bacteria,2GU27@201174|Actinobacteria,4DK67@85008|Micromonosporales	201174|Actinobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,TM2
k59_127536_2	1235835.C814_01875	8.8e-35	131.0	COG4666@1|root,COG4666@2|Bacteria,1VRFB@1239|Firmicutes,24BX2@186801|Clostridia	186801|Clostridia	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_39464_1	1125863.JAFN01000001_gene492	2.86e-56	190.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_62590_1	1265505.ATUG01000003_gene517	3.64e-26	102.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria,2MN9A@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_39467_1	796942.HMPREF9623_01889	9.21e-10	65.1	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
k59_174047_1	398767.Glov_3473	2.12e-26	105.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA TolQ ExbB proton channel	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_174047_2	715226.ABI_18000	1.29e-21	91.3	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,2KGV5@204458|Caulobacterales	204458|Caulobacterales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k59_145113_1	5911.EAR96184	1.18e-13	75.5	KOG1075@1|root,KOG1075@2759|Eukaryota,3ZF6V@5878|Ciliophora	5878|Ciliophora	H	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162914_1	269797.Mbar_A1800	3.38e-30	123.0	COG1520@1|root,COG3291@1|root,arCOG02550@1|root,arCOG03991@1|root,arCOG02482@2157|Archaea,arCOG02510@2157|Archaea,arCOG02550@2157|Archaea,arCOG03991@2157|Archaea,2XUI1@28890|Euryarchaeota,2NBKW@224756|Methanomicrobia	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM_6,DUF3344,NosD,PKD,PQQ_2,PQQ_3,Pkinase
k59_86287_1	555088.DealDRAFT_2903	8.72e-124	375.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,42K30@68298|Syntrophomonadaceae	186801|Clostridia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_127550_1	697281.Mahau_2130	1.04e-53	171.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,42G97@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_74496_3	439375.Oant_1631	5.57e-05	47.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,1J1WU@118882|Brucellaceae	28211|Alphaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_92005_1	1121472.AQWN01000012_gene1007	4.09e-68	215.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,260TX@186807|Peptococcaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
k59_57079_1	682795.AciX8_0374	1.22e-37	145.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria,2JHZB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_86289_1	1173020.Cha6605_0321	5.49e-36	127.0	COG0251@1|root,COG0251@2|Bacteria,1G6TD@1117|Cyanobacteria	1117|Cyanobacteria	J	endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_86289_2	1278307.KB907017_gene3468	4.36e-20	89.7	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Mechanosensitive Ion channel	mscS	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_151049_1	57918.XP_004309313.1	1.75e-108	313.0	COG0090@1|root,KOG0438@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,4JTF7@91835|fabids	35493|Streptophyta	J	50S ribosomal protein	rpl2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C,Ribosomal_S19
k59_151049_2	3880.AES88257	3.52e-34	118.0	COG0185@1|root,KOG0899@2759|Eukaryota,37W5Z@33090|Viridiplantae,3GKJU@35493|Streptophyta,4JVCU@91835|fabids	35493|Streptophyta	J	30S ribosomal protein S19	rps19	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_156484_1	331869.BAL199_08188	1.41e-08	61.2	COG5433@1|root,COG5433@2|Bacteria,1PY8T@1224|Proteobacteria,2UGIG@28211|Alphaproteobacteria,4BT36@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
k59_74504_1	1047013.AQSP01000140_gene2448	2.57e-59	193.0	COG0372@1|root,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1,4.1.3.34	ko:K01647,ko:K15234	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R00351,R00354	RC00004,RC00067,RC00502	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_127564_1	7739.XP_002607510.1	1.11e-11	70.9	2CZ7H@1|root,2S8WZ@2759|Eukaryota,3965E@33154|Opisthokonta,3C5P7@33208|Metazoa,3DM5D@33213|Bilateria,48MFT@7711|Chordata	33208|Metazoa	S	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	MULE
k59_86302_1	1250006.JHZZ01000001_gene867	0.000157	51.6	COG3055@1|root,COG3291@1|root,COG4625@1|root,COG4886@1|root,COG5276@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,COG5276@2|Bacteria,4NMJ3@976|Bacteroidetes,1HYVY@117743|Flavobacteriia,3VX3K@52959|Polaribacter	976|Bacteroidetes	I	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF285,TSP_3
k59_103671_1	1397527.Q670_14855	1.63e-05	50.1	COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1XIQ4@135619|Oceanospirillales	135619|Oceanospirillales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_151053_2	515635.Dtur_0638	1.35e-40	145.0	COG1163@1|root,COG1163@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
k59_168820_2	521011.Mpal_0672	0.000387	42.4	arCOG02576@1|root,arCOG02576@2157|Archaea,2XZNM@28890|Euryarchaeota,2N9WU@224756|Methanomicrobia	224756|Methanomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_114964_1	4565.Traes_2AL_FE7DBC113.1	2e-100	301.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta,3M2Z2@4447|Liliopsida,3ID3P@38820|Poales	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa
k59_114964_2	29760.VIT_00s0246g00010.t01	7.65e-18	82.8	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GKAG@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase ubiquinone iron-sulfur protein 2-like	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa
k59_114964_3	264402.Cagra.23916s0001.1.p	1.84e-55	184.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta,3HY69@3699|Brassicales	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k59_114964_5	4555.Si020764m	2.02e-55	186.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta,3M2Z2@4447|Liliopsida,3ID3P@38820|Poales	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	nad7	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k59_114964_6	3988.XP_002535340.1	1.74e-119	342.0	2CN0V@1|root,2QT6Q@2759|Eukaryota,37TTJ@33090|Viridiplantae,3GIGX@35493|Streptophyta,4JPJH@91835|fabids	35493|Streptophyta	S	60S ribosomal protein L5	rpl5	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1990904	-	-	-	-	-	-	-	-	-	-	-
k59_114964_8	3702.ATMG00220.1	4.24e-290	791.0	COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,3GF4E@35493|Streptophyta	35493|Streptophyta	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis	cob	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_162940_1	546269.HMPREF0389_00562	9.07e-68	224.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,25QC5@186804|Peptostreptococcaceae	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_4197_1	1242864.D187_010010	5.42e-22	95.9	COG0475@1|root,COG0475@2|Bacteria,1NRVM@1224|Proteobacteria,42ZBH@68525|delta/epsilon subdivisions,2WU4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	glutathione-regulated potassium exporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_4197_2	440512.C211_03090	6.07e-23	99.4	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_9948_1	1499683.CCFF01000013_gene324	2.49e-133	390.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_162946_1	290397.Adeh_2927	1.95e-19	93.2	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,43CAR@68525|delta/epsilon subdivisions,2X7M8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86317_1	945713.IALB_2283	2.55e-96	308.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_45091_1	406124.ACPC01000018_gene2516	2.86e-34	123.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus	91061|Bacilli	P	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_74523_2	459349.CLOAM1790	1.29e-18	87.8	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
k59_57109_1	552811.Dehly_0917	5.68e-33	128.0	COG2081@1|root,COG2081@2|Bacteria,2GBTN@200795|Chloroflexi,34CND@301297|Dehalococcoidia	301297|Dehalococcoidia	S	FAD dependent oxidoreductase	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_174097_1	1191523.MROS_2800	3.63e-253	701.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
k59_186001_1	203122.Sde_0148	2.31e-52	182.0	COG0438@1|root,COG0438@2|Bacteria,1R3X9@1224|Proteobacteria,1S184@1236|Gammaproteobacteria,465Z5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_174105_2	1499967.BAYZ01000044_gene2997	3.98e-11	61.6	COG1595@1|root,COG1595@2|Bacteria,2NR5T@2323|unclassified Bacteria	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_74541_1	1499684.CCNP01000021_gene2639	1.17e-43	161.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,36EMP@31979|Clostridiaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_162972_1	288000.BBta_6814	1.1e-41	156.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,3JQV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_115773_1	404589.Anae109_3003	1.07e-58	196.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_24610_1	59538.XP_005980196.1	4.61e-54	208.0	KOG1075@1|root,KOG4776@1|root,KOG1075@2759|Eukaryota,KOG4776@2759|Eukaryota,3A2BJ@33154|Opisthokonta,3BR1K@33208|Metazoa,3D7JS@33213|Bilateria,48GGU@7711|Chordata,49DSU@7742|Vertebrata,3JQE2@40674|Mammalia	33208|Metazoa	K	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Exo_endo_phos_2
k59_12875_1	861299.J421_0962	2.28e-08	59.7	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_89117_1	903818.KI912268_gene3427	1.14e-105	313.0	COG1484@1|root,COG1484@2|Bacteria,3Y6NW@57723|Acidobacteria	57723|Acidobacteria	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_89117_2	903818.KI912268_gene3428	1.4e-136	409.0	COG4584@1|root,COG4584@2|Bacteria,3Y6WU@57723|Acidobacteria	57723|Acidobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89117_3	903818.KI912268_gene3429	5.42e-37	140.0	COG1475@1|root,COG1475@2|Bacteria,3Y7ZH@57723|Acidobacteria	57723|Acidobacteria	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
k59_171523_1	1121447.JONL01000002_gene1823	2.8e-86	300.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WJF3@28221|Deltaproteobacteria,2M98U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_47988_1	7029.ACYPI52973-PA	2.1e-105	338.0	28PS4@1|root,2QWEM@2759|Eukaryota,39STS@33154|Opisthokonta,3BM2D@33208|Metazoa,3D4ZE@33213|Bilateria,420QK@6656|Arthropoda,3SNGI@50557|Insecta	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7,Tnp_zf-ribbon_2
k59_136147_1	675814.VIC_000152	5.02e-08	62.8	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XT6V@135623|Vibrionales	135623|Vibrionales	H	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB	btuB	GO:0003674,GO:0005215	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_71466_2	237368.SCABRO_01815	1.51e-25	102.0	COG1633@1|root,COG1633@2|Bacteria,2J3M5@203682|Planctomycetes	203682|Planctomycetes	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_83279_1	1379698.RBG1_1C00001G0462	1.41e-33	127.0	COG2067@1|root,COG2067@2|Bacteria,2NPVZ@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83279_2	224325.AF_1002	2.67e-28	108.0	COG2062@1|root,arCOG01992@2157|Archaea,2Y26Y@28890|Euryarchaeota,24776@183980|Archaeoglobi	183980|Archaeoglobi	T	Histidine phosphatase superfamily (branch 1)	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_118597_2	1280692.AUJL01000005_gene1690	8.81e-47	169.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,36E2C@31979|Clostridiaceae	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_18512_1	1230338.MOMA_05060	3.54e-06	50.1	COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1SATV@1236|Gammaproteobacteria,3NJ7K@468|Moraxellaceae	1236|Gammaproteobacteria	NT	Two component signalling adaptor domain	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
k59_130235_1	234267.Acid_7639	1.08e-159	461.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria	57723|Acidobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
k59_165699_1	66875.JODY01000001_gene4845	2.9e-12	67.8	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_118601_1	404589.Anae109_2925	1.6e-25	110.0	COG1404@1|root,COG3940@1|root,COG1404@2|Bacteria,COG3940@2|Bacteria,1RCVP@1224|Proteobacteria	1224|Proteobacteria	O	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
k59_18517_1	518766.Rmar_0086	3.22e-79	245.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1FJJ9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_48007_1	1121451.DESAM_20397	2.29e-22	100.0	COG3829@1|root,COG4191@1|root,COG4564@1|root,COG5002@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,COG4564@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42N6Y@68525|delta/epsilon subdivisions,2WJVA@28221|Deltaproteobacteria,2M8BT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,NMT1,PAS_3,PAS_4,Response_reg,dCache_1,sCache_2
k59_7018_1	518766.Rmar_1442	7.74e-64	211.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1FIY8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_65771_1	110319.CF8_2789	2.34e-06	55.8	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4DNY1@85009|Propionibacteriales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_54020_1	82654.Pse7367_0584	3.7e-57	202.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_65779_1	290402.Cbei_2099	1.71e-05	50.1	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_71493_1	469381.Dpep_2027	5.13e-113	337.0	COG0156@1|root,COG0156@2|Bacteria,3TAG5@508458|Synergistetes	508458|Synergistetes	H	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_48022_1	8010.XP_010867459.1	6.61e-33	129.0	2CMVD@1|root,2QS6T@2759|Eukaryota,38ITZ@33154|Opisthokonta,3BGFP@33208|Metazoa,3D162@33213|Bilateria,482X8@7711|Chordata,493ZA@7742|Vertebrata,49VC1@7898|Actinopterygii	33208|Metazoa	S	EPM2A (laforin) interacting protein 1	EPM2AIP1	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,GTF2I
k59_77450_2	1031288.AXAA01000008_gene1237	2.46e-05	47.0	COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,25EB0@186801|Clostridia,36UIY@31979|Clostridiaceae	186801|Clostridia	KQ	Sigma54 specific transcriptional regulator, Fis family	aorR	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat
k59_77450_4	1501230.ET33_07120	3.57e-09	57.0	COG0789@1|root,COG0789@2|Bacteria,1VDPP@1239|Firmicutes,4HPJY@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_77450_9	339671.Asuc_1210	1.51e-34	130.0	COG0417@1|root,COG0417@2|Bacteria,1QVMG@1224|Proteobacteria,1T2EP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
k59_77450_10	1304866.K413DRAFT_1196	6.92e-46	160.0	COG0629@1|root,COG0629@2|Bacteria,1UI1P@1239|Firmicutes,24MGJ@186801|Clostridia	186801|Clostridia	L	ERF superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ERF
k59_30526_1	926692.AZYG01000051_gene1844	1.75e-77	237.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WB9U@53433|Halanaerobiales	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
k59_77456_1	439235.Dalk_5180	1.82e-126	370.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MIMJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_153674_1	398767.Glov_3304	6.17e-28	119.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2WJS0@28221|Deltaproteobacteria,43U0P@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_54035_1	588596.U9SSF9	3.6e-57	199.0	2CMNC@1|root,2QQZ0@2759|Eukaryota,39MPM@33154|Opisthokonta,3NXJA@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
k59_182988_1	98439.AJLL01000096_gene4132	2.51e-29	122.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,TPR_1,TPR_8,Thioesterase
k59_1113_1	1395587.P364_0127975	3.87e-43	154.0	COG4335@1|root,COG4335@2|Bacteria,1TRE4@1239|Firmicutes,4HA0G@91061|Bacilli,26RB3@186822|Paenibacillaceae	91061|Bacilli	L	DNA alkylation repair	yhaZ	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_136205_1	247490.KSU1_B0100	2.89e-177	505.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_59827_1	349741.Amuc_0573	3.21e-38	143.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia,2IU03@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_171554_1	1231057.AMGD01000007_gene2465	1.59e-61	204.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,26CXG@186818|Planococcaceae	91061|Bacilli	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_112637_1	485916.Dtox_4188	1.63e-49	174.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26020@186807|Peptococcaceae	186801|Clostridia	EH	Anthranilate synthase component I	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
k59_54049_1	696747.NIES39_D06190	2.47e-39	142.0	COG0745@1|root,COG0745@2|Bacteria,1G1RN@1117|Cyanobacteria,1HAC1@1150|Oscillatoriales	1117|Cyanobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K11329	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_54049_2	517417.Cpar_1258	2.1e-39	140.0	COG0193@1|root,COG0193@2|Bacteria,1FES3@1090|Chlorobi	1090|Chlorobi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_89171_1	306281.AJLK01000116_gene4291	4.23e-26	100.0	COG0432@1|root,COG0432@2|Bacteria,1G61Z@1117|Cyanobacteria,1JKCA@1189|Stigonemataceae	1117|Cyanobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_42990_1	192952.MM_1893	3.95e-95	291.0	COG0641@1|root,arCOG00945@2157|Archaea,2Y0F7@28890|Euryarchaeota,2NAGD@224756|Methanomicrobia	224756|Methanomicrobia	K	SEC-C motif	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
k59_60482_2	697281.Mahau_0729	1.34e-55	182.0	COG0454@1|root,COG0456@2|Bacteria,1V40T@1239|Firmicutes,250X6@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130105_7	1408303.JNJJ01000049_gene2733	6e-100	317.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,1ZEKP@1386|Bacillus	91061|Bacilli	L	DNA polymerase A domain	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A
k59_24534_1	6412.HelroP163959	3.36e-33	140.0	2CZ63@1|root,2S8NK@2759|Eukaryota,39HPZ@33154|Opisthokonta,3CMHR@33208|Metazoa,3DJ85@33213|Bilateria	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas,zf-C2H2,zf-CCHC,zf-H2C2_5
k59_124411_1	215358.XP_010754736.1	1.46e-45	161.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3C0YC@33208|Metazoa,3DH14@33213|Bilateria,48RUJ@7711|Chordata,49N81@7742|Vertebrata,4A97P@7898|Actinopterygii	33208|Metazoa	S	RNA-directed DNA polymerase from mobile element jockey-like	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_65652_1	335543.Sfum_2413	1.06e-26	113.0	COG3523@1|root,COG3523@2|Bacteria,1NRHK@1224|Proteobacteria,42Z87@68525|delta/epsilon subdivisions,2WTYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182883_2	671143.DAMO_1182	1.37e-75	231.0	COG0717@1|root,COG0717@2|Bacteria,2NQ5G@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
k59_65653_1	448385.sce7213	1.88e-41	141.0	COG1670@1|root,COG1670@2|Bacteria,1PEJD@1224|Proteobacteria,43DWD@68525|delta/epsilon subdivisions,2WZ1V@28221|Deltaproteobacteria,2Z2FW@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k59_42181_1	6183.Smp_195130.1	2.56e-141	449.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_53906_1	866771.HMPREF9296_0566	4.63e-24	108.0	2DKMJ@1|root,309XW@2|Bacteria,4NNRT@976|Bacteroidetes,2FQNM@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase C10 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I69,Peptidase_C10
k59_65659_1	1379698.RBG1_1C00001G1552	3.5e-08	61.6	COG1657@1|root,COG2931@1|root,COG4625@1|root,COG1657@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.1.3.1,3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01077,ko:K01119,ko:K11751,ko:K20276	ko00230,ko00240,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,ko02024,map00230,map00240,map00730,map00760,map00790,map01100,map01110,map02020,map02024	M00126	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02135,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R04620,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Cadherin-like,DUF4430,Flg_new,He_PIG,SLH
k59_71397_1	2711.XP_006485021.1	1.73e-16	85.9	28PQ2@1|root,2QWCA@2759|Eukaryota,37NA7@33090|Viridiplantae,3GAAP@35493|Streptophyta	35493|Streptophyta	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_165609_1	1330700.JQNC01000003_gene1945	6.81e-05	50.1	COG0795@1|root,COG0795@2|Bacteria,1WI9J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_159555_1	479434.Sthe_1982	2.69e-29	116.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi,27Y9N@189775|Thermomicrobia	189775|Thermomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_30394_1	292459.STH3258	4.37e-24	99.4	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_165612_1	32057.KB217478_gene2689	1.08e-10	67.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1G065@1117|Cyanobacteria,1HMSS@1161|Nostocales	1117|Cyanobacteria	LV	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k59_118466_1	70601.3258262	1.82e-15	80.5	COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,242ZK@183968|Thermococci	183968|Thermococci	J	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_59699_1	1322246.BN4_12276	2.09e-33	133.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2M8PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_83207_1	1267535.KB906767_gene1739	2.21e-11	75.5	COG1075@1|root,COG1749@1|root,COG1075@2|Bacteria,COG1749@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4082,Flagellin_N,Flg_bb_rod,Flg_bbr_C
k59_65687_1	398767.Glov_2305	1.18e-38	141.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_94965_1	688270.Celal_2696	1.17e-64	229.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia,1FA5V@104264|Cellulophaga	976|Bacteroidetes	C	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
k59_71413_1	631362.Thi970DRAFT_04444	1.07e-83	266.0	COG3464@1|root,COG3464@2|Bacteria,1N5CJ@1224|Proteobacteria,1T4WB@1236|Gammaproteobacteria,1WZSX@135613|Chromatiales	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_990_1	102107.XP_008224000.1	4.65e-238	710.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta,4JREA@91835|fabids	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	ycf1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	-	-	-	-	-	-	-	-	-	Ycf1
k59_990_2	3880.AES85855	5.09e-06	50.4	2E30T@1|root,2SA69@2759|Eukaryota,37XUE@33090|Viridiplantae,3GMF3@35493|Streptophyta,4JVFX@91835|fabids	35493|Streptophyta	S	Cell wall-associated hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141913_1	443143.GM18_2882	6.39e-126	372.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria	1224|Proteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k59_182903_2	400682.PAC_15713733	7.7e-109	339.0	28KB6@1|root,2QSS1@2759|Eukaryota,39XKI@33154|Opisthokonta,3BJUI@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	THAP
k59_89102_1	861299.J421_0240	1.15e-21	101.0	COG2091@1|root,COG2091@2|Bacteria,1ZUPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_6949_1	1379698.RBG1_1C00001G1851	8.05e-11	66.6	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K03407,ko:K07648,ko:K07679,ko:K11356	ko02020,ko02026,ko02030,ko05133,map02020,map02026,map02030,map05133	M00456,M00477,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HTH_18,HisKA,Hpt,PAS_3,PAS_4,PAS_7,Reg_prop,Response_reg,Y_Y_Y
k59_6949_2	709991.Odosp_2856	4.56e-12	69.7	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia,22Y0S@171551|Porphyromonadaceae	976|Bacteroidetes	S	membrane	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
k59_136093_1	880073.Calab_1153	9.37e-40	147.0	COG0591@1|root,COG0591@2|Bacteria,2NRJT@2323|unclassified Bacteria	2|Bacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_65722_1	234267.Acid_0012	4.62e-23	105.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_147789_1	643648.Slip_0909	2.4e-32	121.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,42K4P@68298|Syntrophomonadaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_130188_1	221109.22777554	7.88e-14	79.7	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,23JMB@182709|Oceanobacillus	91061|Bacilli	KT	Sigma-54 interaction domain	bkdR	-	-	-	-	-	-	-	-	-	-	-	DapB_N,HTH_8,PAS,Sigma54_activat
k59_24595_1	400668.Mmwyl1_4205	1.76e-47	167.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,1RZGN@1236|Gammaproteobacteria,1XPAH@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
k59_165651_1	1353276.JADR01000001_gene750	5.61e-58	194.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1HX2J@117743|Flavobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k59_89116_1	649747.HMPREF0083_04764	7.96e-24	99.0	COG1943@1|root,COG1943@2|Bacteria,1UMJI@1239|Firmicutes,4ITX2@91061|Bacilli,26YV5@186822|Paenibacillaceae	91061|Bacilli	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_100855_1	512565.AMIS_470	1.1e-17	87.4	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DAUE@85008|Micromonosporales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_47970_1	7029.ACYPI42956-PA	5.95e-21	101.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A278@33154|Opisthokonta,3C5WU@33208|Metazoa,3DG3H@33213|Bilateria,422D9@6656|Arthropoda,3SR1F@50557|Insecta	33154|Opisthokonta	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	ko:K10443	-	-	-	-	ko00000,ko04121	-	-	-	Exo_endo_phos_2,RNase_H,RVT_1
k59_165658_1	517418.Ctha_1163	2.16e-62	209.0	COG1538@1|root,COG1538@2|Bacteria,1FDFP@1090|Chlorobi	1090|Chlorobi	MU	PFAM outer membrane efflux protein	-	-	-	ko:K12340,ko:K12543	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00330,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2,3.A.1.109.4	-	-	OEP
k59_83252_1	590998.Celf_1107	8.1e-58	202.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4F0FB@85016|Cellulomonadaceae	201174|Actinobacteria	L	TIGRFAM ATP-dependent DNA helicase PcrA	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_83252_2	929562.Emtol_3908	3.32e-36	132.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,47JVW@768503|Cytophagia	976|Bacteroidetes	S	phenazine biosynthesis protein PhzF family	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k59_106802_1	1206735.BAGG01000262_gene6610	3.99e-18	91.3	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4FWW4@85025|Nocardiaceae	201174|Actinobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_6976_1	591158.SSMG_02997	4.9e-11	66.6	COG1309@1|root,COG1309@2|Bacteria,2GNYI@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, tetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
k59_112576_1	879212.DespoDRAFT_00289	1.04e-33	126.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_112576_2	879212.DespoDRAFT_01215	3.09e-49	167.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_107323_1	1206720.BAFQ01000134_gene3333	5.26e-33	121.0	COG0299@1|root,COG0299@2|Bacteria,2IGFU@201174|Actinobacteria,4G2H2@85025|Nocardiaceae	201174|Actinobacteria	F	Formyl transferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_119255_1	1530186.JQEY01000002_gene1596	2.67e-78	255.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_48604_1	225117.XP_009366572.1	4.71e-21	91.3	2CV7H@1|root,2RRGK@2759|Eukaryota,383A9@33090|Viridiplantae,3GS0R@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_171842_1	7897.ENSLACP00000005018	7.13e-92	293.0	KOG1121@1|root,KOG1121@2759|Eukaryota,39TTD@33154|Opisthokonta,3BCXB@33208|Metazoa,3E42X@33213|Bilateria,48QQW@7711|Chordata,49MAJ@7742|Vertebrata	33208|Metazoa	L	RNA polymerase II regulatory region DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_83882_1	4098.XP_009587381.1	2.25e-11	69.3	COG2801@1|root,KOG0017@2759|Eukaryota,37SNQ@33090|Viridiplantae,3GHRQ@35493|Streptophyta,44SCF@71274|asterids	35493|Streptophyta	L	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	Retrotran_gag_2,gag_pre-integrs,rve,zf-CCHC
k59_18843_3	1121346.KB899808_gene3376	8.26e-29	114.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_101242_1	7029.ACYPI061166-PA	8.95e-33	134.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,41WI3@6656|Arthropoda,3SIRK@50557|Insecta,3ECJT@33342|Paraneoptera	33208|Metazoa	O	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Baculo_F,RVT_1,rve
k59_160152_1	7897.ENSLACP00000010693	1.58e-10	66.2	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria,48QHZ@7711|Chordata,497ZU@7742|Vertebrata	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_124828_1	1177928.TH2_05443	1.37e-32	131.0	COG0603@1|root,COG0603@2|Bacteria,1MXFU@1224|Proteobacteria,2U0CR@28211|Alphaproteobacteria,2JV36@204441|Rhodospirillales	204441|Rhodospirillales	F	Queuosine biosynthesis protein QueC	-	-	-	-	-	-	-	-	-	-	-	-	QueC
k59_36902_1	6412.HelroP163959	1.56e-28	121.0	2CZ63@1|root,2S8NK@2759|Eukaryota,39HPZ@33154|Opisthokonta,3CMHR@33208|Metazoa,3DJ85@33213|Bilateria	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas,zf-C2H2,zf-CCHC,zf-H2C2_5
k59_1453_1	1286170.RORB6_02060	3.73e-27	104.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rmlC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_42643_1	1463920.JOGB01000133_gene1082	1.21e-06	53.1	COG3845@1|root,COG3845@2|Bacteria,2I2Y2@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k59_36909_1	945713.IALB_2259	1.21e-91	281.0	COG2008@1|root,COG2008@2|Bacteria	2|Bacteria	E	L-allo-threonine aldolase activity	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_36909_2	1046724.KB889862_gene1430	1.81e-14	68.2	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,4689P@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_48399_1	3847.GLYMA13G11980.1	3.13e-56	194.0	2CUMQ@1|root,2RN4M@2759|Eukaryota,37U2D@33090|Viridiplantae,3GX5D@35493|Streptophyta,4JTXP@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_18866_1	227377.CBU_0175	4.23e-11	62.0	COG0515@1|root,COG0515@2|Bacteria,1NUIB@1224|Proteobacteria	1224|Proteobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_18866_2	61459.XP_007779953.1	1.65e-15	76.6	COG0311@1|root,KOG3210@2759|Eukaryota,38C2M@33154|Opisthokonta,3NZ52@4751|Fungi,3QPFU@4890|Ascomycota,20BX0@147545|Eurotiomycetes,3MPTB@451870|Chaetothyriomycetidae	4751|Fungi	H	glutamine amidotransferase	SNO1	GO:0003674,GO:0003824,GO:0004359,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009987,GO:0010941,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051186,GO:0051188,GO:0060548,GO:0065007,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
k59_30908_1	568816.Acin_0791	1.06e-07	54.3	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4H2PQ@909932|Negativicutes	909932|Negativicutes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_30908_2	536232.CLM_0970	7.61e-70	226.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,36EFV@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
k59_130632_1	338966.Ppro_0772	6.17e-28	108.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,43UY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_142287_3	518766.Rmar_0226	2.26e-13	70.9	COG5557@1|root,COG5557@2|Bacteria,4PKRP@976|Bacteroidetes,1FIRC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Quinol cytochrome C oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54361_1	411476.BACOVA_04108	1.03e-97	313.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia,4ANNP@815|Bacteroidaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_20b,Glyco_hydro_67N
k59_171725_1	32264.tetur02g12680.1	4.19e-29	120.0	COG1301@1|root,KOG3787@2759|Eukaryota,38C9Y@33154|Opisthokonta,3BD67@33208|Metazoa,3CWZP@33213|Bilateria,41TS6@6656|Arthropoda	33208|Metazoa	P	amino acid transporter	-	-	-	ko:K05613,ko:K05614	ko04724,ko05014,map04724,map05014	-	-	-	ko00000,ko00001,ko02000,ko04147	2.A.23.2.1,2.A.23.2.2	-	-	SDF
k59_183256_1	1380600.AUYN01000003_gene213	2.93e-10	58.9	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1I3Q8@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_183256_2	1343739.PAP_01055	2.55e-46	158.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota,243YD@183968|Thermococci	183968|Thermococci	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_30912_1	335541.Swol_1779	1.54e-87	273.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,42JKU@68298|Syntrophomonadaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_101250_3	926566.Terro_3127	3.34e-90	290.0	COG0210@1|root,COG0210@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
k59_101250_7	1264700.L0MX86_9CAUD	2.38e-155	467.0	4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses  no RNA stage,4QPWY@28883|Caudovirales,4QJW9@10662|Myoviridae	10662|Myoviridae	S	nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95543_2	1121946.AUAX01000039_gene5766	6.16e-46	153.0	COG0615@1|root,COG0615@2|Bacteria,2HPY9@201174|Actinobacteria,4DGI6@85008|Micromonosporales	201174|Actinobacteria	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
k59_54371_1	604354.TSIB_1115	4.1e-48	174.0	COG1543@1|root,arCOG03281@2157|Archaea,2XW5I@28890|Euryarchaeota,24389@183968|Thermococci	183968|Thermococci	G	Belongs to the glycosyl hydrolase 57 family	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0030978,GO:0030979,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57,HHH_5
k59_71862_1	1499967.BAYZ01000005_gene5438	9.76e-49	170.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_160223_1	443255.SCLAV_0948	2.94e-22	102.0	COG0457@1|root,COG1192@1|root,COG0457@2|Bacteria,COG1192@2|Bacteria,2GIWN@201174|Actinobacteria	201174|Actinobacteria	D	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,NB-ARC,TIR_2,TPR_10,TPR_12,TPR_4
k59_48427_1	1379698.RBG1_1C00001G0237	4.28e-08	63.2	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,LVIVD
k59_54384_1	6087.XP_002159051.2	5.61e-21	97.8	2AENI@1|root,2RYW1@2759|Eukaryota,39ZI9@33154|Opisthokonta,3BE6W@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95564_1	6087.XP_002159051.2	1.42e-29	122.0	2AENI@1|root,2RYW1@2759|Eukaryota,39ZI9@33154|Opisthokonta,3BE6W@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160240_1	497321.C664_10622	3.25e-09	63.2	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,2VRK0@28216|Betaproteobacteria,2KWDG@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_71870_1	400682.PAC_15705889	4.95e-31	127.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3C0YC@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_60197_1	880073.Calab_2075	1.99e-20	95.5	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119111_2	51511.ENSCSAVP00000009856	1.66e-100	328.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,487I3@7711|Chordata	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	ko:K04257	ko04740,map04740	-	-	-	ko00000,ko00001,ko04030	-	-	-	Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_36974_1	1195236.CTER_4399	2.14e-108	338.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,3WH1K@541000|Ruminococcaceae	186801|Clostridia	E	TIGRFAM oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_36974_2	768671.ThimaDRAFT_4076	5.91e-18	79.0	COG0824@1|root,COG0824@2|Bacteria,1N63F@1224|Proteobacteria,1SB06@1236|Gammaproteobacteria,1WYXM@135613|Chromatiales	135613|Chromatiales	S	PFAM thioesterase superfamily	-	-	3.1.2.28	ko:K12073	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT_2
k59_66217_1	531844.FIC_01206	5.76e-21	94.7	COG0582@1|root,COG0582@2|Bacteria,4PMWP@976|Bacteroidetes,1IK01@117743|Flavobacteriia	976|Bacteroidetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_160252_1	316067.Geob_0628	1.45e-77	241.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2WJDN@28221|Deltaproteobacteria,43TGB@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_83697_2	579405.Dd703_1996	2.55e-13	74.3	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,2JCIM@204037|Dickeya	1236|Gammaproteobacteria	L	PFAM integrase family protein	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
k59_25165_1	3880.AES58603	2.47e-13	69.3	COG1007@1|root,KOG4668@2759|Eukaryota,37KKM@33090|Viridiplantae,3GCSG@35493|Streptophyta,4JT2P@91835|fabids	35493|Streptophyta	C	Proton-conducting membrane transporter	nad2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_113487_1	1192034.CAP_4070	2.91e-75	233.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,42VIT@68525|delta/epsilon subdivisions,2WS62@28221|Deltaproteobacteria,2YZJ3@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k59_25991_1	416591.Tlet_1163	2.91e-27	110.0	COG3608@1|root,COG3608@2|Bacteria,2GE1R@200918|Thermotogae	200918|Thermotogae	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_25991_2	1235835.C814_01874	1.18e-20	91.3	28NEN@1|root,2ZBH5@2|Bacteria,1VH0Z@1239|Firmicutes,24IXB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_90190_1	1296415.JACC01000014_gene940	1.93e-15	81.3	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,4NF1M@976|Bacteroidetes,1I4B1@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Peptidase_S8_N
k59_154745_1	1121374.KB891578_gene3269	3.02e-13	75.1	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2K9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_43168_1	1242864.D187_006073	4.58e-23	100.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42Y66@68525|delta/epsilon subdivisions,2WU83@28221|Deltaproteobacteria,2YX71@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_83784_1	997346.HMPREF9374_0230	8.77e-78	245.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,27BA9@186824|Thermoactinomycetaceae	91061|Bacilli	E	Aminomethyltransferase folate-binding domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_83784_2	997884.HMPREF1068_02814	2.33e-57	188.0	2DBB3@1|root,2Z85F@2|Bacteria,4NKCY@976|Bacteroidetes,2FPU7@200643|Bacteroidia,4AKZQ@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
k59_25297_2	1379698.RBG1_1C00001G0842	3.85e-28	112.0	COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_177865_1	1123274.KB899406_gene1253	1.81e-11	68.9	COG4690@1|root,COG4690@2|Bacteria,2J5N0@203691|Spirochaetes	203691|Spirochaetes	E	Dipeptidase	-	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
k59_101366_1	880073.Calab_0515	3.56e-64	208.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_112999_1	1379698.RBG1_1C00001G0115	5.81e-67	214.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31049_1	526218.Sterm_2007	8.09e-21	98.2	COG0305@1|root,COG0305@2|Bacteria,3784X@32066|Fusobacteria	32066|Fusobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_31049_6	398720.MED217_15020	6.79e-30	111.0	2E9WC@1|root,33I4C@2|Bacteria,4NZAQ@976|Bacteroidetes,1IIV9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136769_1	335543.Sfum_0617	5.03e-32	127.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria,2MQZB@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Integral membrane sensor signal transduction histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA,dCache_1,dCache_2
k59_18961_1	1126950.G9J2B2_9CAUD	2.17e-270	765.0	4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses  no RNA stage,4QSGM@28883|Caudovirales,4QK1H@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_18961_2	113395.AXAI01000008_gene1059	1.19e-12	67.4	2DXRV@1|root,3467M@2|Bacteria,1PAVV@1224|Proteobacteria,2UXWN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_177881_1	646529.Desaci_3622	2.91e-83	265.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_125001_1	178901.AmDm5_2869	6.31e-33	128.0	COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,2TSG7@28211|Alphaproteobacteria,2JZM8@204441|Rhodospirillales	204441|Rhodospirillales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_119207_1	1192034.CAP_2598	6.52e-48	169.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42Q78@68525|delta/epsilon subdivisions,2WJHK@28221|Deltaproteobacteria,2YU6Z@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
k59_37105_1	1121405.dsmv_2856	1.68e-114	349.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136784_1	6412.HelroP160109	1.09e-19	89.4	2EF8Y@1|root,2SKGS@2759|Eukaryota,3AHXD@33154|Opisthokonta,3BZNB@33208|Metazoa,3DFRE@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371
k59_177895_1	643648.Slip_1042	1.63e-44	159.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,42JRQ@68298|Syntrophomonadaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_130805_1	7668.SPU_005861-tr	1.11e-116	355.0	28IIP@1|root,2QQVP@2759|Eukaryota,39TA7@33154|Opisthokonta,3CNWS@33208|Metazoa,3D3DK@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_83823_1	31234.CRE13338	8.94e-42	152.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_42838_1	765912.Thimo_2331	4.73e-24	97.1	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1WXAH@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_95743_1	756499.Desde_3371	1.14e-05	50.4	COG1309@1|root,COG1309@2|Bacteria,1V44X@1239|Firmicutes,24HI1@186801|Clostridia,261ZY@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_89580_1	797302.Halru_3039	1.39e-30	118.0	COG4122@1|root,arCOG00979@2157|Archaea,2XUMZ@28890|Euryarchaeota,23SXY@183963|Halobacteria	183963|Halobacteria	S	O-methyltransferase, family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
k59_89580_2	247633.GP2143_11759	1.19e-07	55.5	COG2146@1|root,COG2146@2|Bacteria,1NWKP@1224|Proteobacteria	1224|Proteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
k59_177905_2	69014.TK1316	7.69e-25	102.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota,243FX@183968|Thermococci	183968|Thermococci	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_66369_1	1519464.HY22_13435	1.84e-84	278.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	hybA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_48547_1	1122927.KB895412_gene895	5.63e-35	132.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HBWI@91061|Bacilli,275PR@186822|Paenibacillaceae	91061|Bacilli	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
k59_31094_1	1463825.JNXC01000034_gene2626	6.31e-29	118.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria,4DXMD@85010|Pseudonocardiales	201174|Actinobacteria	M	membrane protein involved in D-alanine export	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
k59_83846_1	880073.Calab_0505	2.04e-61	212.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_60333_1	7955.ENSDARP00000109600	1.12e-26	110.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3B9WN@33208|Metazoa,3D1S8@33213|Bilateria,48C1W@7711|Chordata,49N8J@7742|Vertebrata,4A5PS@7898|Actinopterygii	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_101410_1	38654.XP_006029730.1	8.99e-114	342.0	2CXPK@1|root,2RYWI@2759|Eukaryota,3A0FF@33154|Opisthokonta,3BPTP@33208|Metazoa,3D6SN@33213|Bilateria,48FM6@7711|Chordata,49CCX@7742|Vertebrata	33208|Metazoa	S	Transposase (partial DDE domain)	-	-	2.1.1.43	ko:K11433	ko00310,map00310	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	DDE_3,HTH_Tnp_Tc3_2,Transposase_1
k59_95776_1	335543.Sfum_3868	5.1e-40	139.0	COG0703@1|root,COG0703@2|Bacteria,1NEB0@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13469_1	7029.ACYPI062923-PA	1.02e-72	244.0	KOG1721@1|root,KOG1721@2759|Eukaryota,39Y18@33154|Opisthokonta,3BJ7C@33208|Metazoa,3CRRQ@33213|Bilateria	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_95786_1	247633.GP2143_15661	2.15e-18	90.1	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1J5T7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_160481_1	1297742.A176_03860	1.85e-13	70.5	COG2304@1|root,COG2304@2|Bacteria,1Q3BR@1224|Proteobacteria,433ZK@68525|delta/epsilon subdivisions,2X48R@28221|Deltaproteobacteria,2YYI2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k59_25382_2	6326.BUX.s00036.28	2.41e-46	167.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_154272_1	631362.Thi970DRAFT_02055	3.21e-77	245.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_101428_2	1089550.ATTH01000001_gene1830	1.35e-34	125.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_154279_1	1209989.TepiRe1_1477	3.73e-64	207.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,42EWC@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_178885_1	7897.ENSLACP00000009489	2.76e-28	117.0	2BUCY@1|root,2S232@2759|Eukaryota,3A3U2@33154|Opisthokonta,3BSU1@33208|Metazoa,3D598@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_31958_1	31234.CRE13126	2.2e-34	131.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_131600_1	7668.SPU_013001-tr	3.6e-53	186.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3BSEH@33208|Metazoa,3D91U@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_172332_2	502558.EGYY_14550	1.46e-60	197.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CUEZ@84998|Coriobacteriia	84998|Coriobacteriia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_84683_1	1089550.ATTH01000001_gene1955	1.57e-07	55.8	2EKPU@1|root,33EDK@2|Bacteria,4P8S4@976|Bacteroidetes,1FJH6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_167116_2	207559.Dde_3641	1.99e-73	240.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2M8PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_31302_1	7897.ENSLACP00000006966	1.7e-31	133.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,487I3@7711|Chordata	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_183682_1	1379698.RBG1_1C00001G0315	1.97e-28	117.0	COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria	2|Bacteria	D	Peptidase family M23	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
k59_125271_1	1519464.HY22_13445	8.63e-29	112.0	COG0109@1|root,COG0109@2|Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k59_125271_2	945713.IALB_0726	2.52e-59	192.0	COG2836@1|root,COG2836@2|Bacteria	2|Bacteria	K	Biogenesis protein	braZ	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2,Ferric_reduct
k59_60613_1	4533.OB11G23960.1	2.64e-55	196.0	COG2801@1|root,KOG4658@1|root,KOG0017@2759|Eukaryota,KOG4658@2759|Eukaryota,38226@33090|Viridiplantae,3GV16@35493|Streptophyta,3M2YJ@4447|Liliopsida,3IKZD@38820|Poales	35493|Streptophyta	T	disease resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,PAH
k59_178239_1	517418.Ctha_1164	1.23e-58	205.0	COG0841@1|root,COG0841@2|Bacteria,1FDHA@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_107548_1	1009370.ALO_16147	4.08e-06	55.5	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,4H2KU@909932|Negativicutes	909932|Negativicutes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_107548_2	1303518.CCALI_01128	4.65e-10	62.8	COG1538@1|root,COG1538@2|Bacteria	1303518.CCALI_01128|-	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_113244_1	518766.Rmar_1484	9.4e-19	90.5	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
k59_60629_1	1121396.KB893077_gene741	2.43e-78	248.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42YYU@68525|delta/epsilon subdivisions,2WU8G@28221|Deltaproteobacteria,2MN6U@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pfam:DUF377	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_160794_1	246197.MXAN_3195	1.02e-60	209.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_16,AAA_5,GerE
k59_31336_2	1123274.KB899408_gene3763	4.97e-10	67.8	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes	203691|Spirochaetes	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_89873_1	1192034.CAP_0302	6.87e-69	217.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	prp1	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
k59_137127_1	671143.DAMO_0821	1.39e-88	274.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k59_183714_1	1267534.KB906761_gene1228	6.45e-08	57.0	COG4932@1|root,COG4932@2|Bacteria,3Y9AV@57723|Acidobacteria,2JP0F@204432|Acidobacteriia	204432|Acidobacteriia	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_131090_1	290512.Paes_2297	2.18e-89	279.0	COG3547@1|root,COG3547@2|Bacteria,1FEII@1090|Chlorobi	1090|Chlorobi	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_142742_1	1379698.RBG1_1C00001G0445	2.08e-89	287.0	COG0542@1|root,COG0542@2|Bacteria,2NNKN@2323|unclassified Bacteria	2|Bacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_178275_1	1123320.KB889698_gene9323	2.42e-09	63.2	COG2133@1|root,COG3055@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,GSDH,Laminin_G_3,Malectin,PKD
k59_89896_1	177437.HRM2_41800	3.55e-84	265.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_101634_1	740709.A10D4_06286	2.68e-62	214.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,2QF77@267893|Idiomarinaceae	1236|Gammaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_37400_1	1205908.AKXW01000001_gene3226	6.49e-58	195.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,1SZV7@1236|Gammaproteobacteria,1Y2X9@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_125319_2	945713.IALB_1400	3.83e-17	85.5	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	rtxA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	ASH,CBM_2,Calx-beta,DUF4214,FlgD_ig,HemolysinCabind,SdrD_B
k59_19172_2	107636.JQNK01000002_gene92	2.73e-34	130.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria	1224|Proteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,HTH_Tnp_Mu_1,Mu-transpos_C,rve
k59_131113_1	1379698.RBG1_1C00001G1315	5.1e-64	206.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_48903_1	224325.AF_0545	1.02e-32	123.0	COG2181@1|root,arCOG02196@2157|Archaea	2157|Archaea	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_78246_1	7668.SPU_005381-tr	1.57e-26	113.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3CNFK@33208|Metazoa,3E4K9@33213|Bilateria	33208|Metazoa	L	retrotransposable element Tf2 155 kDa protein type 1-like	-	-	-	-	-	-	-	-	-	-	-	-	PNMA,RVT_1,rve,zf-H2C2
k59_66610_1	1288826.MSNKSG1_13187	1.36e-87	283.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,465HN@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_436,iECOK1_1307.ECOK1_1491,iECS88_1305.ECS88_1416,iJN746.PP_2112,iUMN146_1321.UM146_10390,iUTI89_1310.UTI89_C1547	Aconitase,Aconitase_C
k59_43138_1	1038869.AXAN01000035_gene2146	8.97e-08	50.4	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2VTIQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_43138_2	867903.ThesuDRAFT_01262	3.78e-07	53.5	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WCS7@538999|Clostridiales incertae sedis	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_131116_1	1033734.CAET01000005_gene3724	2.53e-50	175.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	ycbD	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_7895_2	1210884.HG799463_gene9521	3.39e-08	56.2	2DF1X@1|root,2ZQ60@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160844_1	207559.Dde_0534	8.78e-11	67.4	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,42TNX@68525|delta/epsilon subdivisions,2WQWE@28221|Deltaproteobacteria	1224|Proteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_29,rve
k59_25728_1	3656.XP_008460615.1	4.13e-221	662.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta,4JM10@91835|fabids	35493|Streptophyta	H	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Chromo,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_166619_1	27923.ML35653a-PA	0.000898	47.0	COG4886@1|root,KOG0531@2759|Eukaryota	2759|Eukaryota	L	axoneme assembly	-	-	-	ko:K16606	-	-	-	-	ko00000,ko04812	-	-	-	Guanylate_kin,LRR_9
k59_84192_1	224308.BSU28550	2.73e-07	55.8	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,1ZAU5@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	fadR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
k59_84192_2	1189612.A33Q_2127	5.16e-17	80.1	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,47JXU@768503|Cytophagia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_172015_1	649638.Trad_0559	5.47e-17	82.8	COG2120@1|root,COG2120@2|Bacteria,1WIUY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
k59_13776_1	439235.Dalk_4801	6.85e-188	532.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_119500_1	1254432.SCE1572_40740	1.24e-13	75.5	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2Z30T@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_38066_1	7029.ACYPI42496-PA	9.3e-10	65.9	KOG1075@1|root,KOG1075@2759|Eukaryota,3A278@33154|Opisthokonta,3BQC7@33208|Metazoa,3D3FI@33213|Bilateria,422CS@6656|Arthropoda,3SUI6@50557|Insecta,3ECF5@33342|Paraneoptera	33208|Metazoa	S	Endonuclease-reverse transcriptase	-	-	-	ko:K10443	-	-	-	-	ko00000,ko04121	-	-	-	Exo_endo_phos_2,RNase_H,RVT_1
k59_155106_1	1267534.KB906756_gene19	4.92e-86	260.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_155106_2	97138.C820_02692	1.42e-05	47.8	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,36ETV@31979|Clostridiaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_55422_1	8081.XP_008399118.1	7.87e-52	178.0	COG2036@1|root,KOG1744@1|root,KOG1744@2759|Eukaryota,KOG1745@2759|Eukaryota,39ZTV@33154|Opisthokonta,3BPDH@33208|Metazoa,3D6BK@33213|Bilateria,48E1W@7711|Chordata,49B7M@7742|Vertebrata,4A9G0@7898|Actinopterygii	33208|Metazoa	B	Core histone H2A/H2B/H3/H4	-	-	-	ko:K11253,ko:K11254	ko05034,ko05202,ko05203,ko05322,map05034,map05202,map05203,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	CENP-T_C,Histone
k59_78892_1	761193.Runsl_2271	1.31e-116	349.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KFX@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
k59_184319_1	45351.EDO33494	3.35e-26	113.0	KOG0613@1|root,KOG4756@1|root,KOG0613@2759|Eukaryota,KOG4756@2759|Eukaryota,3A1SY@33154|Opisthokonta	33154|Opisthokonta	J	structural constituent of ribosome	MRPL41	GO:0000313,GO:0000315,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0006412,GO:0006414,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019866,GO:0022411,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032984,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0070125,GO:0070126,GO:0071704,GO:0071840,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K17422	-	-	-	-	br01610,ko00000,ko03011	-	-	-	MRP-L27
k59_14447_1	649349.Lbys_3463	0.000176	43.5	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,47KYF@768503|Cytophagia	976|Bacteroidetes	S	PFAM ABC transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_14447_3	1379698.RBG1_1C00001G0112	2.21e-30	115.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26403_1	797209.ZOD2009_08279	1.19e-101	309.0	COG0626@1|root,arCOG00060@2157|Archaea,2XT98@28890|Euryarchaeota,23S23@183963|Halobacteria	183963|Halobacteria	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metB	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
k59_2478_1	7029.ACYPI28067-PA	3.04e-160	489.0	2BXPG@1|root,2S2FM@2759|Eukaryota,3A3WK@33154|Opisthokonta,3BRCR@33208|Metazoa,3D8NG@33213|Bilateria,42C7E@6656|Arthropoda,3SS4S@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60129_1	448385.sce1086	1.97e-27	111.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2YW51@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
k59_60129_2	756272.Plabr_0919	3.53e-25	110.0	COG1409@1|root,COG1409@2|Bacteria,2J2TN@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_136561_1	1499680.CCFE01000025_gene3246	1.12e-10	67.0	28MBK@1|root,2ZAQ1@2|Bacteria,1TSWC@1239|Firmicutes,4HCSW@91061|Bacilli,1ZM5I@1386|Bacillus	91061|Bacilli	M	Arylsulfotransferase Ig-like domain	astA	-	2.8.2.22	ko:K01023	-	-	-	-	ko00000,ko01000	-	-	-	Arylsulfotran_N,Arylsulfotrans
k59_171700_1	7425.NV20563-PA	0.00029	52.8	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RNase_H,RVT_1
k59_83611_1	909663.KI867150_gene2871	5.42e-157	461.0	COG3039@1|root,COG3039@2|Bacteria,1QY2X@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6
k59_25071_1	329726.AM1_5416	2.47e-36	129.0	COG1943@1|root,COG1943@2|Bacteria,1G9TK@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_101239_1	7029.ACYPI061409-PA	5.55e-26	115.0	KOG1121@1|root,KOG1121@2759|Eukaryota,39WQ2@33154|Opisthokonta,3BJ35@33208|Metazoa,3CVNM@33213|Bilateria	33208|Metazoa	L	protein dimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,zf-BED
k59_101239_2	8128.ENSONIP00000001685	1.17e-37	144.0	KOG1121@1|root,KOG1121@2759|Eukaryota,39WQ2@33154|Opisthokonta,3BJ35@33208|Metazoa,3CVNM@33213|Bilateria,48AHQ@7711|Chordata,49589@7742|Vertebrata,4A78S@7898|Actinopterygii	33208|Metazoa	L	Zinc finger BED domain-containing protein 1-like	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,zf-BED
k59_66766_1	6412.HelroP125444	7.15e-08	58.2	COG0494@1|root,KOG4432@2759|Eukaryota,38E94@33154|Opisthokonta,3BDUN@33208|Metazoa,3D4DC@33213|Bilateria	33208|Metazoa	L	UDP-sugar diphosphatase activity	NUDT14	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0008768,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047631,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	3.6.1.45	ko:K08077	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
k59_101794_1	8128.ENSONIP00000026579	1.42e-76	249.0	29FBP@1|root,2RNH8@2759|Eukaryota,39ZNK@33154|Opisthokonta,3BMIM@33208|Metazoa,3E4D5@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_107726_1	1192034.CAP_3069	6.33e-09	60.8	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	cglB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,HemolysinCabind,Tad,VWA,VWA_2
k59_2029_1	1240350.AMZE01000026_gene4670	1.22e-13	74.7	COG0787@1|root,COG0787@2|Bacteria,1NXDA@1224|Proteobacteria,1RU2U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr2	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_8019_1	5722.XP_001324432.1	8.48e-25	104.0	COG1109@1|root,KOG1220@2759|Eukaryota	2759|Eukaryota	G	alginic acid metabolic process	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_8019_2	670487.Ocepr_0894	1.79e-20	88.6	COG0483@1|root,COG0483@2|Bacteria,1WIZ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_137329_1	3983.cassava4.1_020914m	9.52e-134	381.0	COG0092@1|root,2QV63@2759|Eukaryota,37ITR@33090|Viridiplantae,3GH7T@35493|Streptophyta,4JSQ4@91835|fabids	35493|Streptophyta	J	Belongs to the universal ribosomal protein uS3 family	rps3	GO:0002181,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3_C
k59_137329_2	59689.fgenesh1_pm.C_scaffold_2000596	2.41e-67	209.0	COG0091@1|root,KOG1711@2759|Eukaryota,37WS8@33090|Viridiplantae,3GJJC@35493|Streptophyta	35493|Streptophyta	J	50S ribosomal protein L22, chloroplastic	rpl22	GO:0000313,GO:0000315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0015934,GO:0031967,GO:0031974,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0098798,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_137329_3	4572.TRIUR3_00332-P1	2.39e-20	86.7	COG0090@1|root,COG0185@1|root,KOG0438@2759|Eukaryota,KOG0899@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,3KTF6@4447|Liliopsida,3IGGK@38820|Poales	35493|Streptophyta	J	structural constituent of ribosome	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2_C,Ribosomal_S19
k59_178487_1	583355.Caka_0651	6.78e-85	271.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,46UJK@74201|Verrucomicrobia,3K9E7@414999|Opitutae	414999|Opitutae	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_54988_1	880071.Fleli_0252	6.32e-59	204.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,47KKB@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_54988_2	391038.Bphy_7618	1.14e-126	377.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2VJ2W@28216|Betaproteobacteria,1K2WR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_13889_1	679926.Mpet_2494	5.38e-48	166.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y8D0@28890|Euryarchaeota,2NAAK@224756|Methanomicrobia	224756|Methanomicrobia	S	radical SAM domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_13889_2	318464.IO99_12830	3.8e-06	54.3	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,24A6D@186801|Clostridia,36G9K@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k59_49053_1	1519439.JPJG01000040_gene1444	7.81e-32	132.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,2N69M@216572|Oscillospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
k59_161010_1	218284.CCDN010000001_gene609	1.77e-66	232.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_183911_1	666681.M301_1490	2.47e-37	140.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_49068_1	1501391.LG35_08955	7.29e-65	222.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,22U5P@171550|Rikenellaceae	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_31557_2	1232437.KL662007_gene1686	2.77e-166	469.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42UXI@68525|delta/epsilon subdivisions,2WQST@28221|Deltaproteobacteria,2MKNI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA breaking-rejoining enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_25938_1	1343158.SACS_1113	5.68e-28	112.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,2JPMQ@204441|Rhodospirillales	204441|Rhodospirillales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_19319_3	7668.SPU_025111-tr	1.21e-103	338.0	28M7P@1|root,2QTQS@2759|Eukaryota,39Z9X@33154|Opisthokonta,3BNGS@33208|Metazoa,3D442@33213|Bilateria	33208|Metazoa	S	cellular response to interferon-beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43144_1	3880.AES58582	1.24e-269	747.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,3GBUN@35493|Streptophyta	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k59_43144_2	3988.XP_002535305.1	3.01e-18	82.0	2ES36@1|root,2SURG@2759|Eukaryota,381I4@33090|Viridiplantae,3GQIR@35493|Streptophyta,4JVFZ@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43144_3	264402.Cagra.8346s0002.1.p	4.29e-47	163.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,3GBUN@35493|Streptophyta,3HYCY@3699|Brassicales	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)	-	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k59_43144_4	3760.EMJ04673	5.52e-11	70.5	2EHFI@1|root,2SN44@2759|Eukaryota,380JJ@33090|Viridiplantae,3GQ86@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Retrotrans_gag
k59_43144_17	29730.Gorai.001G167400.1	8.46e-108	313.0	298BV@1|root,2RFCF@2759|Eukaryota,37JP6@33090|Viridiplantae,3GEH6@35493|Streptophyta	35493|Streptophyta	C	ATP synthase protein	atp4	-	-	-	-	-	-	-	-	-	-	-	Mt_ATP-synt_B
k59_25939_1	1033806.HTIA_0303	2.97e-08	54.7	COG0045@1|root,arCOG01337@2157|Archaea,2XTSC@28890|Euryarchaeota,23S0H@183963|Halobacteria	183963|Halobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_25939_2	867903.ThesuDRAFT_00371	5.22e-10	63.2	COG0617@1|root,COG2254@1|root,COG0617@2|Bacteria,COG2254@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WCIJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
k59_8047_2	96561.Dole_2741	7.93e-48	159.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MJTB@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_166803_1	941449.dsx2_0351	2.4e-75	244.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2M8G8@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_78453_1	933262.AXAM01000046_gene140	3.17e-78	248.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2MI0S@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
k59_90141_6	665942.HMPREF1022_03269	2.39e-08	56.6	2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria,432C4@68525|delta/epsilon subdivisions,2WXM5@28221|Deltaproteobacteria,2MFUS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknwon function (DUF3310)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3310
k59_154701_1	400682.PAC_15702057	2.65e-104	337.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,zf-RVT
k59_137371_1	929704.Myrod_1429	3.06e-21	98.2	COG4772@1|root,COG4772@2|Bacteria,4PKTE@976|Bacteroidetes,1HYQZ@117743|Flavobacteriia,47H36@76831|Myroides	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_2087_1	398767.Glov_3709	2.25e-73	231.0	COG2801@1|root,COG2801@2|Bacteria,1MVQ9@1224|Proteobacteria,42N7N@68525|delta/epsilon subdivisions,2WKJF@28221|Deltaproteobacteria,43SEN@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_80951_1	384676.PSEEN4635	2.93e-47	164.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	atoB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_28174_1	107636.JQNK01000002_gene91	5.47e-38	135.0	2BZBC@1|root,32R4Q@2|Bacteria,1RICW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45511_1	1382356.JQMP01000004_gene103	4.56e-45	160.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,27XV0@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_115448_1	1408433.JHXV01000002_gene442	1.32e-36	142.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
k59_156926_1	383372.Rcas_3465	1.73e-72	232.0	COG3385@1|root,COG3385@2|Bacteria,2G80K@200795|Chloroflexi	200795|Chloroflexi	L	sptr a7nhu5	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_80966_1	161934.XP_010693568.1	2.42e-21	103.0	28HC0@1|root,2QPQD@2759|Eukaryota,37QN4@33090|Viridiplantae,3GNMU@35493|Streptophyta	35493|Streptophyta	S	hAT family C-terminal dimerisation region	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_50840_1	1201288.M900_2528	8.01e-05	46.2	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2MSM4@213481|Bdellovibrionales,2WJ57@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_50840_2	1111479.AXAR01000001_gene133	1.03e-06	53.5	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,278FG@186823|Alicyclobacillaceae	91061|Bacilli	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09935	ACT,PDT
k59_92510_1	3649.evm.model.supercontig_24.81	1.72e-11	63.2	COG2801@1|root,KOG0017@2759|Eukaryota,37Y5M@33090|Viridiplantae,3GN8P@35493|Streptophyta,3HTAU@3699|Brassicales	35493|Streptophyta	L	transposition, RNA-mediated	-	-	5.2.1.8	ko:K14826	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Retrotrans_gag,zf-CCHC
k59_39948_2	7029.ACYPI30841-PA	7.71e-46	176.0	2CY1J@1|root,2S1BE@2759|Eukaryota,3A4Q6@33154|Opisthokonta,3BRW8@33208|Metazoa,3D9KI@33213|Bilateria,422F1@6656|Arthropoda	33208|Metazoa	O	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	MULE,Prok-RING_4,Tnp_P_element,zf-C3HC4_3
k59_21766_2	1121403.AUCV01000008_gene1602	4.77e-28	108.0	COG3295@1|root,COG3295@2|Bacteria,1RFI2@1224|Proteobacteria,42XJC@68525|delta/epsilon subdivisions,2WSKA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM_like_2
k59_63109_1	1210884.HG799463_gene9868	4.59e-96	319.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2IX3H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
k59_151467_1	384616.Pisl_1495	2.88e-27	110.0	COG0438@1|root,arCOG01403@2157|Archaea,2XQAU@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_151467_2	316067.Geob_3377	2.35e-26	109.0	COG0392@1|root,COG0392@2|Bacteria,1R98C@1224|Proteobacteria,42U6V@68525|delta/epsilon subdivisions,2WKTZ@28221|Deltaproteobacteria,43W1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_174586_1	1238450.VIBNISOn1_1810035	6.85e-08	53.9	COG0454@1|root,COG0456@2|Bacteria,1RA6D@1224|Proteobacteria,1S2F2@1236|Gammaproteobacteria,1Y27K@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_33833_1	1162668.LFE_2206	2.8e-87	268.0	COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae	40117|Nitrospirae	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_99052_1	439235.Dalk_1568	3.16e-127	374.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2MIS1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	qmoA	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,NAD_binding_8,Pyr_redox_2
k59_69377_1	517418.Ctha_0317	1.06e-83	276.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_163454_1	861299.J421_1881	1.64e-72	227.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,PD40
k59_115464_1	395495.Lcho_1296	5.08e-71	236.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,1KJ0K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k59_16665_1	1313421.JHBV01000043_gene3107	2.18e-11	71.6	COG1520@1|root,COG2931@1|root,COG3291@1|root,COG4935@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI1E@976|Bacteroidetes,1IYUU@117747|Sphingobacteriia	976|Bacteroidetes	Q	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_50869_1	1236976.JCM16418_67	8.06e-16	76.6	COG1670@1|root,COG1670@2|Bacteria,1V365@1239|Firmicutes,4HJKZ@91061|Bacilli,275IB@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Acetyltransf_4
k59_156948_2	1402135.SUH3_08905	7.43e-44	152.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,2TT92@28211|Alphaproteobacteria,3ZVJI@60136|Sulfitobacter	28211|Alphaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
k59_99076_1	8496.XP_006273030.1	5.13e-08	59.7	KOG3656@1|root,KOG3656@2759|Eukaryota,39TZB@33154|Opisthokonta,3BIU7@33208|Metazoa,3CZF5@33213|Bilateria,4880S@7711|Chordata,493PG@7742|Vertebrata	33208|Metazoa	T	V1A vasopressin receptor binding	AVPR1A	GO:0000003,GO:0001101,GO:0001558,GO:0001653,GO:0001664,GO:0001990,GO:0001992,GO:0002027,GO:0002118,GO:0002125,GO:0002791,GO:0003008,GO:0003013,GO:0003014,GO:0003018,GO:0003044,GO:0003073,GO:0003084,GO:0003674,GO:0004888,GO:0004930,GO:0005000,GO:0005080,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005886,GO:0005887,GO:0005981,GO:0006091,GO:0006109,GO:0006873,GO:0006874,GO:0006875,GO:0006885,GO:0006950,GO:0007154,GO:0007165,GO:0007186,GO:0007202,GO:0007204,GO:0007275,GO:0007320,GO:0007399,GO:0007417,GO:0007420,GO:0007610,GO:0007617,GO:0007618,GO:0007620,GO:0007621,GO:0007625,GO:0008015,GO:0008016,GO:0008150,GO:0008152,GO:0008217,GO:0008284,GO:0008528,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009719,GO:0009725,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010460,GO:0010517,GO:0010518,GO:0010565,GO:0010604,GO:0010646,GO:0010648,GO:0010675,GO:0010676,GO:0010817,GO:0010863,GO:0010906,GO:0010907,GO:0012505,GO:0012506,GO:0014048,GO:0014049,GO:0014070,GO:0014902,GO:0016020,GO:0016021,GO:0017046,GO:0019098,GO:0019216,GO:0019217,GO:0019222,GO:0019229,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0019953,GO:0021537,GO:0022414,GO:0023051,GO:0023052,GO:0023057,GO:0030003,GO:0030004,GO:0030154,GO:0030307,GO:0030641,GO:0030659,GO:0030900,GO:0031090,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031392,GO:0031394,GO:0031410,GO:0031644,GO:0031645,GO:0031668,GO:0031893,GO:0031894,GO:0031960,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0032847,GO:0032849,GO:0032870,GO:0032879,GO:0032881,GO:0032890,GO:0032892,GO:0033218,GO:0033554,GO:0033993,GO:0035150,GO:0035176,GO:0035296,GO:0035556,GO:0035809,GO:0035810,GO:0035813,GO:0035815,GO:0038023,GO:0040008,GO:0042127,GO:0042221,GO:0042277,GO:0042304,GO:0042562,GO:0042592,GO:0042631,GO:0042692,GO:0042711,GO:0042713,GO:0043084,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043269,GO:0043270,GO:0043467,GO:0043470,GO:0043471,GO:0044057,GO:0044060,GO:0044062,GO:0044070,GO:0044093,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0044706,GO:0045723,GO:0045777,GO:0045819,GO:0045823,GO:0045834,GO:0045907,GO:0045913,GO:0045923,GO:0045924,GO:0045927,GO:0046883,GO:0046889,GO:0046890,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050878,GO:0050880,GO:0050886,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051146,GO:0051239,GO:0051240,GO:0051241,GO:0051336,GO:0051345,GO:0051384,GO:0051385,GO:0051412,GO:0051453,GO:0051459,GO:0051480,GO:0051703,GO:0051704,GO:0051705,GO:0051716,GO:0051952,GO:0051954,GO:0051955,GO:0051957,GO:0051969,GO:0051970,GO:0055065,GO:0055067,GO:0055074,GO:0055080,GO:0055082,GO:0060089,GO:0060180,GO:0060191,GO:0060193,GO:0060255,GO:0060322,GO:0060746,GO:0061061,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0065009,GO:0070873,GO:0070875,GO:0070887,GO:0071214,GO:0071229,GO:0071310,GO:0071462,GO:0071495,GO:0071496,GO:0071944,GO:0072503,GO:0072507,GO:0080090,GO:0090066,GO:0090087,GO:0090276,GO:0097305,GO:0097708,GO:0097746,GO:0098771,GO:0098801,GO:0104004,GO:1900274,GO:1901652,GO:1901654,GO:1901698,GO:1901700,GO:1901701,GO:1903522,GO:1903524,GO:1903530,GO:1903532,GO:1903793,GO:2001279,GO:2001280	-	ko:K04226	ko04020,ko04072,ko04080,ko04270,map04020,map04072,map04080,map04270	-	-	-	ko00000,ko00001,ko04030	-	-	-	7tm_1,DUF1856
k59_75032_1	1379698.RBG1_1C00001G0519	1.18e-06	55.1	COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
k59_75032_2	999630.TUZN_1590	6.62e-31	119.0	COG1028@1|root,arCOG01259@2157|Archaea,2XPW4@28889|Crenarchaeota	28889|Crenarchaeota	I	PFAM short-chain dehydrogenase reductase SDR	fabG-5	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_28233_1	697284.ERIC2_c00590	5.49e-70	224.0	COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,4HA4Y@91061|Bacilli,26T7E@186822|Paenibacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_186467_1	1191523.MROS_2410	3.12e-72	236.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	porX	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	PglZ,Response_reg
k59_110283_2	1123237.Salmuc_03771	3.38e-57	185.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_122162_1	1463881.KL591018_gene259	9.75e-07	50.1	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_122162_2	517417.Cpar_2077	4.24e-126	372.0	COG0126@1|root,COG0126@2|Bacteria,1FDBD@1090|Chlorobi	1090|Chlorobi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_174628_1	1379698.RBG1_1C00001G0980	7.28e-28	104.0	COG1862@1|root,COG1862@2|Bacteria,2NPY3@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase, YajC	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_174628_2	667014.Thein_0248	3.82e-22	91.3	COG0242@1|root,COG0242@2|Bacteria,2GHK8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_104095_1	59374.Fisuc_1416	1.25e-29	112.0	COG0092@1|root,COG0092@2|Bacteria	2|Bacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_156963_1	448385.sce9225	7.29e-50	162.0	COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions,2WQGU@28221|Deltaproteobacteria,2YVQK@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33864_1	880072.Desac_2850	1.18e-54	181.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,42UXR@68525|delta/epsilon subdivisions,2WQCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_151509_1	641143.HMPREF9331_01500	9.19e-42	152.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,4NKPG@976|Bacteroidetes,1IK5X@117743|Flavobacteriia,1EQ1K@1016|Capnocytophaga	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k59_186478_1	400682.PAC_15710461	6.39e-09	66.6	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,gag-asp_proteas,rve
k59_128059_1	1123228.AUIH01000006_gene2157	2.17e-06	51.6	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XMKX@135619|Oceanospirillales	135619|Oceanospirillales	L	PFAM transposase IS111A IS1328 IS1533, transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_99095_1	452637.Oter_3912	1.01e-33	130.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
k59_99095_2	1254432.SCE1572_26550	8.28e-54	180.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_16702_1	555793.WSK_1970	9.4e-12	70.9	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3VD@28211|Alphaproteobacteria,2K0FN@204457|Sphingomonadales	204457|Sphingomonadales	P	Protein involved in receptor activity and transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_28264_2	13249.RPRC009674-PA	5.12e-12	70.1	KOG1075@1|root,KOG1075@2759|Eukaryota,39X0S@33154|Opisthokonta,3BF48@33208|Metazoa,3D5JC@33213|Bilateria,41X08@6656|Arthropoda,3SJDR@50557|Insecta,3ECS1@33342|Paraneoptera	33208|Metazoa	S	Endonuclease-reverse transcriptase	-	-	2.4.1.17	ko:K00699,ko:K06515	ko00040,ko00053,ko00140,ko00830,ko00860,ko00980,ko00982,ko00983,ko01100,ko01110,ko05204,ko05231,map00040,map00053,map00140,map00830,map00860,map00980,map00982,map00983,map01100,map01110,map05204,map05231	M00014,M00129	R01383,R02358,R02389,R02478,R02502,R02902,R03091,R04352,R04353,R04354,R04683,R07106,R08259,R08261,R08262,R08263,R08615,R09426,R09427,R09428	RC00005,RC00033,RC00049,RC00059,RC00078,RC00171,RC00397,RC00523,RC00529,RC00708,RC02748	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000,ko04090	2.A.92.1.1	GT1	-	Exo_endo_phos,Exo_endo_phos_2,PRE_C2HC,RVT_1
k59_181036_2	1267533.KB906737_gene2024	4.13e-07	50.8	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
k59_186493_1	936136.ARRT01000006_gene5686	1.16e-32	123.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,4B6YF@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_153056_2	644282.Deba_2361	2.04e-37	136.0	COG0674@1|root,COG0674@2|Bacteria,1MWCI@1224|Proteobacteria,42NJY@68525|delta/epsilon subdivisions,2WIW3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_117877_1	272563.CD630_26330	4.73e-47	167.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,25SXA@186804|Peptostreptococcaceae	186801|Clostridia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
k59_170755_2	589873.EP13_05950	4.95e-23	95.1	2DN9P@1|root,32WA7@2|Bacteria,1N472@1224|Proteobacteria,1SHE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135534_1	7029.ACYPI006074-PA	1.76e-07	58.5	COG2801@1|root,KOG0017@2759|Eukaryota,3ASUJ@33154|Opisthokonta,3C44B@33208|Metazoa,3DK2V@33213|Bilateria	7029.ACYPI006074-PA|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_35760_1	1379698.RBG1_1C00001G1000	1.69e-61	193.0	COG1762@1|root,COG1762@2|Bacteria,2NPVC@2323|unclassified Bacteria	2|Bacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
k59_35760_2	868864.Dester_0687	2.23e-12	62.0	COG2835@1|root,COG2835@2|Bacteria,2G4D1@200783|Aquificae	200783|Aquificae	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
k59_153065_2	1121403.AUCV01000005_gene207	6.73e-81	246.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,42TT9@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k59_47424_1	864069.MicloDRAFT_00066940	3.54e-07	53.9	COG1595@1|root,COG1595@2|Bacteria,1RFN0@1224|Proteobacteria,2U8N2@28211|Alphaproteobacteria,1JZD6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_35766_1	926561.KB900617_gene1952	1.42e-30	130.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,24EBQ@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
k59_524_1	794903.OPIT5_09250	7.66e-63	204.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,3K7TI@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_106263_1	382464.ABSI01000005_gene1099	1.15e-38	137.0	COG0396@1|root,COG0396@2|Bacteria,46SGE@74201|Verrucomicrobia,2ITY7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_59194_1	471857.Svir_31520	7.84e-49	167.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4DYE8@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k59_100308_1	27923.ML07701a-PA	8.97e-43	152.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3B9WN@33208|Metazoa	33208|Metazoa	G	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_35777_1	1121087.AUCK01000008_gene2195	3.96e-25	108.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_153091_1	400682.PAC_15711609	9.07e-11	70.1	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3C1BS@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_59199_1	237368.SCABRO_02676	1.4e-52	177.0	COG0823@1|root,COG0823@2|Bacteria,2IXGY@203682|Planctomycetes	203682|Planctomycetes	U	Periplasmic component of the Tol biopolymer transport	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,PDZ_2,Peptidase_M28
k59_170776_1	1191523.MROS_1592	3.89e-118	360.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_106270_1	1500897.JQNA01000002_gene1522	0.0	995.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VNZQ@28216|Betaproteobacteria,1KGKU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_556_2	3847.GLYMA08G41251.1	1.58e-132	378.0	COG0839@1|root,2S14H@2759|Eukaryota,389Z6@33090|Viridiplantae,3GX82@35493|Streptophyta,4JU6G@91835|fabids	35493|Streptophyta	P	NADH-ubiquinone oxidoreductase chain	NAD6	-	1.6.5.3	ko:K03884	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q3
k59_141411_2	1127518.H9C0Z2_9CAUD	1.31e-137	420.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae	10662|Myoviridae	S	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141411_9	360910.BAV1283	2.9e-105	319.0	COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,2W1GI@28216|Betaproteobacteria	28216|Betaproteobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_141411_10	1161931.J7F9D8_9CAUD	5.24e-34	123.0	4QEGD@10239|Viruses,4QVU1@35237|dsDNA viruses  no RNA stage,4QPN9@28883|Caudovirales,4QJCM@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_153094_1	573370.DMR_00680	1.28e-78	249.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2M8C3@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_165029_1	420324.KI911992_gene7770	3.65e-45	165.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,1JUMW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_88601_1	706587.Desti_0562	9.35e-64	210.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQU0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_111998_1	69319.XP_008553387.1	1.05e-24	114.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,41WI3@6656|Arthropoda,3SIRK@50557|Insecta,46IFZ@7399|Hymenoptera	33208|Metazoa	L	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Baculo_F,RRM_1,RVT_1,rve,zf-H2C2
k59_94383_3	1215092.PA6_039_00340	9.81e-59	197.0	COG5526@1|root,COG5526@2|Bacteria,1RA0A@1224|Proteobacteria	1224|Proteobacteria	M	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
k59_59221_1	1379698.RBG1_1C00001G0606	1.01e-101	315.0	COG0173@1|root,COG0173@2|Bacteria,2NNP3@2323|unclassified Bacteria	2|Bacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN678.aspS,iSFV_1184.SFV_1868	GAD,tRNA-synt_2,tRNA_anti-codon
k59_47454_1	40483.S8DZB4	4.7e-11	65.5	COG1791@1|root,KOG2107@2759|Eukaryota,3A1M2@33154|Opisthokonta,3P21X@4751|Fungi,3V0QF@5204|Basidiomycota,228XX@155619|Agaricomycetes,3H4Q9@355688|Agaricomycetes incertae sedis	4751|Fungi	E	Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)	ADI1	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010308,GO:0010309,GO:0016053,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051213,GO:0055114,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
k59_59231_1	382464.ABSI01000011_gene3094	1.95e-75	241.0	COG0388@1|root,COG0388@2|Bacteria,46ZGG@74201|Verrucomicrobia,2IUQ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_112011_1	6087.XP_002170374.2	5.35e-06	48.1	COG0513@1|root,COG1525@1|root,KOG1075@1|root,KOG0331@2759|Eukaryota,KOG1075@2759|Eukaryota,KOG2039@2759|Eukaryota,39T1U@33154|Opisthokonta,3BE7J@33208|Metazoa	33208|Metazoa	A	Tudor domain containing 12	TDRD12	GO:0000003,GO:0000280,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007140,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0009566,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016458,GO:0019222,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0031047,GO:0032259,GO:0032501,GO:0032504,GO:0032991,GO:0034587,GO:0034641,GO:0034660,GO:0043046,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044728,GO:0046483,GO:0048232,GO:0048285,GO:0048519,GO:0048609,GO:0050789,GO:0051321,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0140013,GO:1901360,GO:1903046,GO:1990923	3.6.4.13	ko:K18409	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	CS,DEAD,Helicase_C,TUDOR
k59_117907_1	867902.Ornrh_0645	1.28e-38	148.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_106285_2	469617.FUAG_02781	1.66e-12	65.5	COG0537@1|root,COG0537@2|Bacteria,37ACH@32066|Fusobacteria	32066|Fusobacteria	FG	Histidine triad domain protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_129735_1	399795.CtesDRAFT_PD1152	3.56e-11	67.0	2DQF9@1|root,336H4@2|Bacteria,1N5N6@1224|Proteobacteria,2VT17@28216|Betaproteobacteria,4AHY2@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129735_2	1111479.AXAR01000022_gene1064	1.07e-80	248.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,4IQPN@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
k59_135561_1	1121020.JIAG01000004_gene2145	3.16e-24	103.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter (Permease)	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_135561_2	1379698.RBG1_1C00001G0883	1.94e-56	186.0	COG1175@1|root,COG1175@2|Bacteria,2NPDA@2323|unclassified Bacteria	2|Bacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
k59_147259_1	533240.CRC_01167	1.01e-24	107.0	COG0438@1|root,COG0438@2|Bacteria,1GBU4@1117|Cyanobacteria,1HM6X@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_147259_2	1116472.MGMO_13c00120	1.04e-94	288.0	COG1216@1|root,COG1216@2|Bacteria,1N1TF@1224|Proteobacteria,1RPQU@1236|Gammaproteobacteria,1XE7E@135618|Methylococcales	135618|Methylococcales	S	Glycosyltransferase like family 2	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
k59_12273_1	6087.XP_002168505.2	5.53e-16	84.3	COG0515@1|root,KOG4250@2759|Eukaryota	2759|Eukaryota	KLT	IkappaB kinase activity	IKK1	GO:0001666,GO:0002225,GO:0002230,GO:0002252,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006963,GO:0007154,GO:0007165,GO:0007166,GO:0007249,GO:0007252,GO:0008063,GO:0008150,GO:0008152,GO:0008384,GO:0008385,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009615,GO:0009617,GO:0009628,GO:0009653,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019221,GO:0019222,GO:0019538,GO:0019730,GO:0019731,GO:0023051,GO:0023052,GO:0023057,GO:0030163,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0032502,GO:0032991,GO:0033209,GO:0033554,GO:0034097,GO:0034248,GO:0034250,GO:0034612,GO:0035556,GO:0036211,GO:0036293,GO:0036294,GO:0042221,GO:0042742,GO:0043170,GO:0043207,GO:0043412,GO:0043900,GO:0043902,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045088,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048856,GO:0050688,GO:0050691,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050829,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0061057,GO:0061695,GO:0065007,GO:0065009,GO:0070482,GO:0070887,GO:0071310,GO:0071345,GO:0071356,GO:0071453,GO:0071456,GO:0071704,GO:0080090,GO:0080134,GO:0098542,GO:0140096,GO:1900424,GO:1900426,GO:1901222,GO:1901223,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1902531,GO:1902532,GO:1902554,GO:1902680,GO:1902911,GO:1903506,GO:1903508,GO:1990234,GO:2000112,GO:2001141	2.7.11.10	ko:K04467,ko:K07209	ko01523,ko04010,ko04014,ko04062,ko04064,ko04068,ko04150,ko04151,ko04210,ko04380,ko04620,ko04621,ko04622,ko04623,ko04624,ko04657,ko04658,ko04659,ko04660,ko04662,ko04668,ko04722,ko04910,ko04920,ko04930,ko04931,ko04932,ko05120,ko05131,ko05142,ko05145,ko05160,ko05161,ko05162,ko05164,ko05165,ko05166,ko05167,ko05168,ko05169,ko05200,ko05206,ko05212,ko05215,ko05220,ko05221,ko05222,ko05418,map01523,map04010,map04014,map04062,map04064,map04068,map04150,map04151,map04210,map04380,map04620,map04621,map04622,map04623,map04624,map04657,map04658,map04659,map04660,map04662,map04668,map04722,map04910,map04920,map04930,map04931,map04932,map05120,map05131,map05142,map05145,map05160,map05161,map05162,map05164,map05165,map05166,map05167,map05168,map05169,map05200,map05206,map05212,map05215,map05220,map05221,map05222,map05418	M00686	-	-	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	Pkinase
k59_100359_1	1408433.JHXV01000019_gene1919	5.35e-75	238.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1HXKZ@117743|Flavobacteriia,2PB12@246874|Cryomorphaceae	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
k59_100359_2	1249480.B649_05690	4.67e-42	150.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2YM9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_159060_1	6669.EFX67499	5.07e-32	128.0	2AENI@1|root,2RYW1@2759|Eukaryota,39ZI9@33154|Opisthokonta,3BQBS@33208|Metazoa,3D2GS@33213|Bilateria,41TJ8@6656|Arthropoda	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159060_2	7029.ACYPI072573-PA	2.68e-21	95.5	2AENI@1|root,2RYW1@2759|Eukaryota,39ZI9@33154|Opisthokonta,3BQBS@33208|Metazoa,3D2GS@33213|Bilateria,41TJ8@6656|Arthropoda,3SQF4@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70989_1	7029.ACYPI51791-PA	1.87e-20	92.8	2AENI@1|root,2RYW1@2759|Eukaryota,39ZI9@33154|Opisthokonta,3BQBS@33208|Metazoa,3D2GS@33213|Bilateria,41TJ8@6656|Arthropoda,3SQF4@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123969_1	2325.TKV_c22980	6.13e-108	348.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_29946_1	335543.Sfum_0909	5.14e-115	354.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MS34@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_6470_1	1532557.JL37_10890	1.87e-31	123.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,2VH7J@28216|Betaproteobacteria,3T5JP@506|Alcaligenaceae	28216|Betaproteobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_112065_1	349521.HCH_05429	1.6e-73	247.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XISF@135619|Oceanospirillales	135619|Oceanospirillales	M	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_12298_1	391603.FBALC1_09537	2.65e-21	97.1	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
k59_76931_1	1296415.JACC01000003_gene3135	1.27e-22	102.0	COG2866@1|root,COG3227@1|root,COG3342@1|root,COG2866@2|Bacteria,COG3227@2|Bacteria,COG3342@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia,2YIPC@290174|Aquimarina	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,MAM,Peptidase_M14,Reprolysin_4,fn3
k59_76931_2	243231.GSU2664	9.51e-20	90.1	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
k59_135575_1	3827.XP_004493998.1	9.82e-65	233.0	2C7QK@1|root,2QUNQ@2759|Eukaryota,37QB2@33090|Viridiplantae,3GCE5@35493|Streptophyta,4JRQZ@91835|fabids	35493|Streptophyta	S	source UniProtKB	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_35857_1	1123250.KB908410_gene1947	9.31e-11	66.6	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4H4C8@909932|Negativicutes	909932|Negativicutes	S	D5 N terminal like	-	-	-	-	-	-	-	-	-	-	-	-	D5_N,Pox_D5
k59_147278_1	98439.AJLL01000047_gene2888	8.09e-52	176.0	2DB98@1|root,2Z7VA@2|Bacteria,1G05J@1117|Cyanobacteria,1JHH9@1189|Stigonemataceae	1117|Cyanobacteria	P	Photosystem II protein	psbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_124643_2	56780.SYN_00075	5.38e-35	133.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MR3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k59_178104_1	269799.Gmet_0205	2.59e-60	196.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,43TZK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_37227_1	459349.CLOAM0024	5.26e-25	112.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42995_1	246194.CHY_1170	2.73e-45	156.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_13614_1	1304885.AUEY01000001_gene3164	1.66e-05	47.4	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CS7@68525|delta/epsilon subdivisions,2X7ZW@28221|Deltaproteobacteria,2MPMK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7,PAS_8,PAS_9,Response_reg,SBP_bac_3,sCache_3_2
k59_13614_2	438753.AZC_1807	6.01e-32	119.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2U768@28211|Alphaproteobacteria,3F1IU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	OsmC-like protein	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
k59_101506_1	42099.EPrPV00000021784	5.82e-43	163.0	COG0466@1|root,KOG4366@1|root,KOG2004@2759|Eukaryota,KOG4366@2759|Eukaryota,1ME7Q@121069|Pythiales	121069|Pythiales	O	Lon protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_72187_1	4432.XP_010262237.1	7.98e-16	82.8	COG2801@1|root,KOG0017@2759|Eukaryota,37NRU@33090|Viridiplantae,3GGV0@35493|Streptophyta	35493|Streptophyta	E	L-threonine ammonia-lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	RVP_2,RVT_1,Retrotrans_gag,rve,zf-H2C2
k59_60506_1	643867.Ftrac_3256	2.08e-45	159.0	COG0787@1|root,COG0787@2|Bacteria,4NG3U@976|Bacteroidetes,47KRQ@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_166446_1	290512.Paes_1106	5.28e-50	176.0	COG0842@1|root,COG0842@2|Bacteria,1FD5J@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_166446_2	517417.Cpar_1050	0.000177	44.3	COG0842@1|root,COG0842@2|Bacteria,1FD8A@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_72193_1	7897.ENSLACP00000016254	3.91e-45	167.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,487I3@7711|Chordata,4962T@7742|Vertebrata	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_25558_1	880073.Calab_3323	6.04e-24	105.0	COG1538@1|root,COG1538@2|Bacteria,2NPI8@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_84026_1	1279009.ADICEAN_04200	9.61e-30	110.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
k59_137006_1	1121094.KB894657_gene2568	1.89e-21	91.7	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,4AM7E@815|Bacteroidaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_137006_2	1385935.N836_03185	5.05e-50	164.0	COG0454@1|root,COG0456@2|Bacteria,1G5GC@1117|Cyanobacteria	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
k59_60513_1	281687.CJA04294	1.43e-49	176.0	2CJSR@1|root,2S3U9@2759|Eukaryota,39FYJ@33154|Opisthokonta,3CJTV@33208|Metazoa,3E1D3@33213|Bilateria,40NWR@6231|Nematoda,1M6C5@119089|Chromadorea,414NG@6236|Rhabditida	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29
k59_19082_1	6087.XP_002168351.2	8.15e-25	107.0	KOG2353@1|root,KOG2353@2759|Eukaryota,38H7U@33154|Opisthokonta,3B9G8@33208|Metazoa	33208|Metazoa	PT	voltage-gated calcium channel activity	tag-180	-	-	ko:K04858	ko04010,ko04260,ko04261,ko04921,ko05410,ko05412,ko05414,map04010,map04260,map04261,map04921,map05410,map05412,map05414	-	-	-	ko00000,ko00001,ko04040	8.A.18.1	-	-	VGCC_alpha2,VWA,VWA_3,VWA_N
k59_178144_1	7897.ENSLACP00000002180	5.9e-35	139.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,487FB@7711|Chordata,491IP@7742|Vertebrata	33208|Metazoa	-	-	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_178144_2	7897.ENSLACP00000002180	4.27e-16	83.6	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,487FB@7711|Chordata,491IP@7742|Vertebrata	33208|Metazoa	-	-	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_142633_1	1191523.MROS_1577	4.55e-71	224.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
k59_171926_1	720554.Clocl_1180	6.84e-16	74.7	2BKMI@1|root,32F2Z@2|Bacteria,1W3X5@1239|Firmicutes,254RR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166467_1	373903.Hore_11130	8.18e-76	248.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3WAEZ@53433|Halanaerobiales	186801|Clostridia	S	PFAM OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_107480_1	1121472.AQWN01000009_gene346	1.89e-34	135.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,260M6@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1748_2	1499967.BAYZ01000056_gene4882	3.66e-96	311.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PEP_hydrolase,Sigma54_activat
k59_113187_6	1541065.JRFE01000024_gene1020	8.42e-13	73.2	2EI39@1|root,33BUS@2|Bacteria,1GPCU@1117|Cyanobacteria,3VM2Q@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142641_1	247490.KSU1_C1600	1.12e-89	281.0	COG2148@1|root,COG2148@2|Bacteria,2IYWX@203682|Planctomycetes	203682|Planctomycetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_131013_1	7070.TC004301-PA	2.39e-30	126.0	KOG1056@1|root,KOG1056@2759|Eukaryota,38C5P@33154|Opisthokonta,3B9DN@33208|Metazoa,3CU4N@33213|Bilateria,41WU1@6656|Arthropoda,3SJY4@50557|Insecta	33208|Metazoa	PT	G-protein coupled receptor activity. It is involved in the biological process described with G-protein coupled receptor signaling pathway	GPRMGL5	GO:0003674,GO:0004888,GO:0004930,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0007166,GO:0007186,GO:0007187,GO:0007188,GO:0007193,GO:0007196,GO:0007200,GO:0007215,GO:0007216,GO:0007610,GO:0007631,GO:0008066,GO:0008150,GO:0008343,GO:0009636,GO:0009987,GO:0010646,GO:0016020,GO:0016021,GO:0017085,GO:0023051,GO:0023052,GO:0030425,GO:0030534,GO:0031224,GO:0031226,GO:0032501,GO:0036477,GO:0038023,GO:0042221,GO:0042734,GO:0042995,GO:0043005,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0050789,GO:0050794,GO:0050804,GO:0050896,GO:0051716,GO:0051966,GO:0060089,GO:0065007,GO:0071944,GO:0097060,GO:0097447,GO:0097458,GO:0098590,GO:0098793,GO:0099177,GO:0120025,GO:0120038	-	ko:K04604,ko:K04605,ko:K04608,ko:K04611	ko04020,ko04072,ko04080,ko04540,ko04720,ko04723,ko04724,ko05016,ko05030,map04020,map04072,map04080,map04540,map04720,map04723,map04724,map05016,map05030	-	-	-	ko00000,ko00001,ko01009,ko04030	-	-	-	7tm_3,ANF_receptor,NCD3G
k59_7799_1	1349767.GJA_3998	1.61e-15	80.5	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VHWW@28216|Betaproteobacteria,4731H@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
k59_7799_2	665959.HMPREF1013_01412	1.67e-10	63.2	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes,4HEKF@91061|Bacilli,1ZEG2@1386|Bacillus	91061|Bacilli	S	Polysaccharide biosynthesis protein	cps2J	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_84056_1	574087.Acear_0676	4.93e-25	108.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3WAEZ@53433|Halanaerobiales	186801|Clostridia	S	PFAM OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_131020_1	395964.KE386496_gene367	3.25e-58	191.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,3NBII@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_107492_1	765910.MARPU_08930	5.9e-67	232.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1WWPB@135613|Chromatiales	135613|Chromatiales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg,dCache_3
k59_66505_1	264402.Cagra.5120s0009.1.p	9.03e-12	63.9	29ZPR@1|root,2RXWR@2759|Eukaryota,37U5T@33090|Viridiplantae,3GHWN@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_66505_2	3712.Bo9g074560.1	1.61e-35	136.0	COG0090@1|root,KOG0438@2759|Eukaryota,37TIQ@33090|Viridiplantae,3GHDG@35493|Streptophyta	35493|Streptophyta	J	Ribosomal protein L2	-	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L2
k59_178180_1	548479.HMPREF0573_11662	1.42e-20	94.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4D3D1@85005|Actinomycetales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	LGT
k59_148657_1	330084.JNYZ01000043_gene1546	6.7e-71	226.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4E1MA@85010|Pseudonocardiales	201174|Actinobacteria	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_55520_1	558884.JRGM01000149_gene3623	1.06e-17	87.4	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,1RNSR@1236|Gammaproteobacteria,1Y5HZ@135624|Aeromonadales	135624|Aeromonadales	HQ	Catalyzes the conversion of chorismate to isochorismate	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
k59_8613_1	1304880.JAGB01000002_gene1876	9.81e-44	161.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_8613_2	945713.IALB_0941	4.78e-28	107.0	COG0218@1|root,COG0218@2|Bacteria	2|Bacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_55522_1	59538.XP_005973450.1	2.46e-20	90.5	COG4359@1|root,2QRU0@2759|Eukaryota,39PCC@33154|Opisthokonta	33154|Opisthokonta	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_154904_16	1460640.JCM19046_3530	2.95e-33	136.0	COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,4HHJ7@91061|Bacilli,1ZKIN@1386|Bacillus	91061|Bacilli	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_154904_17	742823.HMPREF9465_00950	1.01e-06	50.8	COG0863@1|root,COG0863@2|Bacteria,1P97D@1224|Proteobacteria,2VW8Z@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_154904_18	1166018.FAES_3931	6.21e-09	58.2	2EQ06@1|root,340RM@2|Bacteria,4PQ0X@976|Bacteroidetes,47YT4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119887_1	1121285.AUFK01000016_gene3581	8.46e-07	55.5	COG1345@1|root,COG3055@1|root,COG4412@1|root,COG4677@1|root,COG1345@2|Bacteria,COG3055@2|Bacteria,COG4412@2|Bacteria,COG4677@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,3ZRBK@59732|Chryseobacterium	976|Bacteroidetes	N	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
k59_2288_1	419947.MRA_0709	5.39e-14	70.5	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,234PZ@1762|Mycobacteriaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_2288_2	1385514.N782_09555	1.04e-50	170.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,2Y90G@289201|Pontibacillus	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_119893_1	1423767.BALU01000012_gene200	6.82e-28	116.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_161220_1	222534.KB893766_gene2941	4.5e-111	345.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_84597_2	378806.STAUR_5630	1.56e-40	144.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_72731_1	1379698.RBG1_1C00001G1225	4.39e-137	411.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
k59_119910_1	498211.CJA_2469	7.52e-60	206.0	COG0663@1|root,COG3693@1|root,COG0663@2|Bacteria,COG3693@2|Bacteria,1Q0SI@1224|Proteobacteria,1S04W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
k59_90412_1	326423.RBAM_015130	9.58e-05	51.6	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8
k59_108050_1	485913.Krac_0317	1.89e-21	95.9	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_61086_1	6087.XP_002163005.2	8.47e-10	66.6	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa	33208|Metazoa	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_137555_1	688270.Celal_1598	4.62e-17	80.9	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia,1F80X@104264|Cellulophaga	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_137555_2	172045.KS04_05235	1.63e-100	298.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1HYVV@117743|Flavobacteriia,34PT1@308865|Elizabethkingia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
k59_43322_1	448385.sce4220	5.98e-13	69.7	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_43322_2	1144275.COCOR_01022	1.19e-26	101.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,2YVNJ@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_149289_1	1173029.JH980292_gene3073	4.55e-11	63.2	COG1850@1|root,COG1850@2|Bacteria,1G05Z@1117|Cyanobacteria,1H8Y8@1150|Oscillatoriales	1117|Cyanobacteria	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_149289_2	13333.ERM97892	1.26e-26	107.0	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta	35493|Streptophyta	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	rbcL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.1.3.15,4.1.1.39,6.4.1.2	ko:K01601,ko:K01963	ko00061,ko00620,ko00630,ko00640,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00630,map00640,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00165,M00166,M00376,M00532	R00024,R00742,R03140,R04386	RC00040,RC00172,RC00253,RC00367,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_143261_1	338963.Pcar_3111	2.79e-77	244.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,43SA9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	treT	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
k59_172256_1	1123376.AUIU01000015_gene483	3.54e-46	161.0	COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae	40117|Nitrospirae	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_102073_2	107636.JQNK01000009_gene1834	1.26e-115	343.0	COG3598@1|root,COG3598@2|Bacteria,1R4GJ@1224|Proteobacteria	1224|Proteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
k59_172261_2	290512.Paes_1739	3.71e-72	235.0	COG0449@1|root,COG0449@2|Bacteria,1FEMH@1090|Chlorobi	1090|Chlorobi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_78731_2	580340.Tlie_1826	2.28e-17	82.0	COG0677@1|root,COG0677@2|Bacteria,3T9YU@508458|Synergistetes	508458|Synergistetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_96752_1	42256.RradSPS_0655	1.71e-24	103.0	COG5002@1|root,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_14262_1	1254432.SCE1572_22600	3.13e-97	294.0	2BKCR@1|root,32ETA@2|Bacteria,1RJ21@1224|Proteobacteria,430EX@68525|delta/epsilon subdivisions,2WVVF@28221|Deltaproteobacteria,2YUQK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_37899_1	56110.Oscil6304_0577	7.41e-45	171.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,1G2F0@1117|Cyanobacteria,1HF0C@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
k59_125808_1	96561.Dole_0888	4.21e-29	119.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria,2MMH4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
k59_125811_1	1254432.SCE1572_42010	9.37e-35	131.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria,2YV9A@29|Myxococcales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_113699_1	7029.ACYPI004939-PA	3.78e-68	234.0	2A600@1|root,2RYAU@2759|Eukaryota,3A7S8@33154|Opisthokonta,3BSPE@33208|Metazoa,3DAFP@33213|Bilateria,42AN2@6656|Arthropoda,3T015@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119968_1	945713.IALB_1644	3e-14	79.3	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_178840_1	1232410.KI421412_gene205	1.32e-17	80.9	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,43SEV@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_96772_1	1121288.AULL01000015_gene180	9.76e-55	187.0	COG3457@1|root,COG3457@2|Bacteria,4NFEJ@976|Bacteroidetes,1HYZY@117743|Flavobacteriia,3ZP6I@59732|Chryseobacterium	976|Bacteroidetes	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
k59_102101_1	1191460.F959_02370	4.43e-82	248.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,1RS58@1236|Gammaproteobacteria,3NP2B@468|Moraxellaceae	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
k59_72783_1	1121438.JNJA01000002_gene3796	2.64e-92	293.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2M7S7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_78752_1	7719.XP_009859567.1	1.21e-49	178.0	2BAKW@1|root,2S0W1@2759|Eukaryota,39A78@33154|Opisthokonta,3BKC6@33208|Metazoa,3CUMK@33213|Bilateria,48DFN@7711|Chordata	33208|Metazoa	S	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	ALS2CR8,MULE,SWIM
k59_108108_1	338969.Rfer_3195	1.08e-22	96.7	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2VHU1@28216|Betaproteobacteria,4ACC2@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_119988_1	880073.Calab_2175	4.37e-43	160.0	COG0488@1|root,COG0488@2|Bacteria,2NNPH@2323|unclassified Bacteria	2|Bacteria	S	ABC transporter	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_149327_1	379066.GAU_2568	2.6e-82	258.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_131571_1	13333.ERN02871	0.0	947.0	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta	35493|Streptophyta	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_131571_3	59689.fgenesh2_kg.2__731__ATCG00480.1	0.0	889.0	COG0055@1|root,KOG1350@2759|Eukaryota,37K5M@33090|Viridiplantae,3GCIP@35493|Streptophyta,3I24X@3699|Brassicales	35493|Streptophyta	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpB	GO:0002376,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008270,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009620,GO:0009628,GO:0009814,GO:0009817,GO:0010287,GO:0010319,GO:0016020,GO:0030312,GO:0031967,GO:0031975,GO:0031976,GO:0031977,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045087,GO:0046872,GO:0046914,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0055035,GO:0071944,GO:0098542,GO:0098796,GO:0098807	3.6.3.14	ko:K02112,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N,ATP-synt_ab,ATP-synt_ab_N
k59_131571_4	981085.XP_010089872.1	2.35e-76	229.0	COG0355@1|root,KOG1758@2759|Eukaryota,37UFP@33090|Viridiplantae,3GIN2@35493|Streptophyta,4JUWB@91835|fabids	35493|Streptophyta	C	ATP synthase epsilon chain	atpE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009526,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009941,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_90462_1	27923.ML48591a-PA	9.07e-71	237.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa	33208|Metazoa	J	protein kinase activity	-	-	2.3.1.15,2.4.2.29	ko:K13506,ko:K15407	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R03789,R09380,R10209	RC00004,RC00039,RC00041,RC00063	ko00000,ko00001,ko00002,ko01000,ko01004,ko03016	-	-	-	Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_49405_1	7029.ACYPI28920-PA	2.67e-59	227.0	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa,3D0QV@33213|Bilateria	7029.ACYPI28920-PA|-	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102109_1	7918.ENSLOCP00000013371	4.01e-43	159.0	28M7P@1|root,2QTQS@2759|Eukaryota,39Z9X@33154|Opisthokonta,3BNGS@33208|Metazoa,3D442@33213|Bilateria	33208|Metazoa	S	cellular response to interferon-beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_96795_1	7029.ACYPI44625-PA	1.59e-66	221.0	2CY9X@1|root,2S32T@2759|Eukaryota,3A52K@33154|Opisthokonta,3BS0M@33208|Metazoa,3D96Q@33213|Bilateria,4238M@6656|Arthropoda,3SS6G@50557|Insecta	7029.ACYPI44625-PA|-	S	hAT family C-terminal dimerisation region	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154967_1	945713.IALB_2581	1.01e-30	123.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55301_1	1249975.JQLP01000003_gene45	1.57e-21	94.7	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia,2P6G8@244698|Gillisia	976|Bacteroidetes	H	Flavoprotein	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_26269_1	345219.Bcoa_1793	8.7e-09	59.7	COG3385@1|root,COG3385@2|Bacteria,1TPH7@1239|Firmicutes,4HB3I@91061|Bacilli,1ZE78@1386|Bacillus	91061|Bacilli	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_2345_2	997346.HMPREF9374_0363	3.47e-64	206.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27BPD@186824|Thermoactinomycetaceae	91061|Bacilli	F	Phosphorylase superfamily	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_32585_1	7029.ACYPI068552-PA	6.06e-55	194.0	2CZQ3@1|root,2SB75@2759|Eukaryota,3ABEA@33154|Opisthokonta,3BWRK@33208|Metazoa,3DIHS@33213|Bilateria	33208|Metazoa	S	Protein of unknown function (DUF 659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT
k59_85405_1	1047013.AQSP01000134_gene1374	1.16e-23	102.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
k59_155331_11	1232449.BAHV02000016_gene1824	2.86e-110	340.0	COG1783@1|root,COG1783@2|Bacteria,1TT85@1239|Firmicutes,24ETQ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
k59_155331_12	290315.Clim_0967	9.87e-15	82.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_155331_13	240302.BN982_00172	6.27e-20	95.5	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,1VIX1@1239|Firmicutes,4HVXR@91061|Bacilli,3NG8C@45667|Halobacillus	2|Bacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,LysM,PG_binding_1,Peptidase_C39_2,SLT,SPOR
k59_155331_19	1298858.AUEL01000019_gene3207	1.66e-36	145.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2TR5F@28211|Alphaproteobacteria,43I34@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_155331_21	632245.CLP_3469	9.05e-17	85.9	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,36F2S@31979|Clostridiaceae	186801|Clostridia	M	synthase	neuB	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_155331_25	1501268.EW14_1467	7.61e-37	144.0	COG0381@1|root,COG0381@2|Bacteria,1GC18@1117|Cyanobacteria,1MNSI@1212|Prochloraceae	1117|Cyanobacteria	M	COG381 UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane	-	-	3.2.1.183,3.2.1.184,5.1.3.14	ko:K01791,ko:K08068,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_155331_29	639282.DEFDS_0378	1.14e-14	77.8	COG1083@1|root,COG1083@2|Bacteria,2GGPI@200930|Deferribacteres	200930|Deferribacteres	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
k59_155331_45	1305836.AXVE01000006_gene428	6.49e-22	100.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HH84@91061|Bacilli,26H9K@186818|Planococcaceae	91061|Bacilli	M	NlpC/P60 family	lytE	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3,SLH
k59_108687_2	1304888.ATWF01000001_gene1661	6.36e-24	103.0	COG2206@1|root,COG2206@2|Bacteria,2GEWY@200930|Deferribacteres	200930|Deferribacteres	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD
k59_90999_1	6412.HelroP195122	5.44e-26	109.0	KOG4012@1|root,KOG4012@2759|Eukaryota,3A3HU@33154|Opisthokonta	33154|Opisthokonta	B	to Saccharomyces cerevisiae HHO1 (YPL127C)	-	GO:0000018,GO:0000228,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006323,GO:0006355,GO:0006996,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0010639,GO:0016043,GO:0019219,GO:0019222,GO:0030261,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031935,GO:0031936,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0033043,GO:0033044,GO:0040029,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0045815,GO:0045893,GO:0045910,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051254,GO:0051276,GO:0060255,GO:0060968,GO:0060969,GO:0065007,GO:0070013,GO:0071103,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1902275,GO:1902680,GO:1903506,GO:1903508,GO:1905268,GO:2000112,GO:2001141,GO:2001251	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	Linker_histone
k59_90999_2	1026970.XP_008824872.1	1.22e-57	196.0	COG2036@1|root,COG5262@1|root,KOG1745@2759|Eukaryota,KOG1756@2759|Eukaryota,KOG3467@2759|Eukaryota,39ZTV@33154|Opisthokonta,3BPDH@33208|Metazoa,3D6BK@33213|Bilateria,48E1W@7711|Chordata,49B7M@7742|Vertebrata,3JEM2@40674|Mammalia,35PS8@314146|Euarchontoglires	33208|Metazoa	B	Histone cluster 1	HIST1H3D	GO:0000228,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006335,GO:0006996,GO:0008150,GO:0009987,GO:0010468,GO:0016043,GO:0019222,GO:0022607,GO:0031490,GO:0031491,GO:0031492,GO:0031497,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0034622,GO:0034723,GO:0034728,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0044877,GO:0050789,GO:0050794,GO:0051259,GO:0051262,GO:0051276,GO:0051290,GO:0051291,GO:0060255,GO:0060968,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0071103,GO:0071824,GO:0071840,GO:0097159,GO:1901363	-	ko:K11253,ko:K11254	ko05034,ko05202,ko05203,ko05322,map05034,map05202,map05203,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	CENP-T_C,Histone,Histone_H2A_C
k59_132188_1	1121440.AUMA01000009_gene695	1.14e-55	185.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria,2M8UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_97415_1	56780.SYN_01300	5.02e-52	172.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2MRFF@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	NeuB family	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
k59_138223_1	6087.XP_004209514.1	1.92e-06	56.6	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_79394_3	7719.XP_002126409.2	7.45e-74	257.0	28S9B@1|root,2QYYT@2759|Eukaryota,39WZH@33154|Opisthokonta,3BHGG@33208|Metazoa,3E527@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67710_1	1120972.AUMH01000011_gene239	1.19e-41	142.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_102711_2	521719.ATXQ01000002_gene2477	4.08e-21	93.2	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RYNH@1236|Gammaproteobacteria,1YDZH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_91017_1	392499.Swit_1518	2.62e-24	108.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2K07V@204457|Sphingomonadales	204457|Sphingomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_14940_1	391625.PPSIR1_32512	2.26e-19	88.2	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_14941_1	795359.TOPB45_1469	3.06e-76	253.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,2GH2Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_167711_1	4081.Solyc01g007640.2.1	0.0	3941.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_143962_1	933262.AXAM01000094_gene2192	1.82e-95	293.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,42M60@68525|delta/epsilon subdivisions,2WITJ@28221|Deltaproteobacteria,2MHXY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_173030_1	1121406.JAEX01000018_gene2820	4.16e-62	211.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2M8NV@213115|Desulfovibrionales	28221|Deltaproteobacteria	DM	PFAM lipopolysaccharide biosynthesis protein	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
k59_38442_1	1236959.BAMT01000005_gene91	9.71e-17	86.3	COG1573@1|root,COG1573@2|Bacteria,1PP10@1224|Proteobacteria,2WA44@28216|Betaproteobacteria,2KNA8@206350|Nitrosomonadales	206350|Nitrosomonadales	L	uracil-dna glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_132218_1	3750.XP_008386065.1	1.49e-116	391.0	COG2801@1|root,KOG0017@2759|Eukaryota,37R0H@33090|Viridiplantae	33090|Viridiplantae	L	Zinc finger MYM-type protein 1-like	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102738_1	760568.Desku_1207	8.9e-48	169.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_38447_1	1191523.MROS_2048	8.31e-23	101.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
k59_167729_1	6412.HelroP172394	4.99e-53	186.0	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa,3E5DG@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49703_1	882.DVU_2976	2.23e-80	252.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2M938@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_49703_2	926549.KI421517_gene3630	1.04e-11	62.8	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_143979_1	448385.sce7428	9.27e-07	53.1	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_97475_1	1163407.UU7_09350	3.69e-58	199.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,1RPM6@1236|Gammaproteobacteria,1X3P7@135614|Xanthomonadales	135614|Xanthomonadales	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_132239_1	1379698.RBG1_1C00001G1772	2.65e-19	89.4	COG0457@1|root,COG0457@2|Bacteria,2NQ3H@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
k59_85787_1	178901.AmDm5_2206	8.36e-41	146.0	2D62R@1|root,32TKD@2|Bacteria,1MZY7@1224|Proteobacteria,2UCFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
k59_9486_1	1379698.RBG1_1C00001G0646	1.48e-168	497.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_127121_1	1410622.JNKY01000015_gene404	3.17e-34	136.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,27JGA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_141940_12	72658.Bostr.14866s0003.1.p	0.0	1040.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,3GEEJ@35493|Streptophyta,3HWMV@3699|Brassicales	35493|Streptophyta	C	Cytochrome C and Quinol oxidase polypeptide I	cox1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k59_48081_1	1288826.MSNKSG1_14142	1.46e-98	301.0	COG0531@1|root,COG0531@2|Bacteria,1NCSX@1224|Proteobacteria,1RND7@1236|Gammaproteobacteria,4695V@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Amino acid permease	yjeH	GO:0000099,GO:0000101,GO:0000102,GO:0001101,GO:0003333,GO:0003674,GO:0005215,GO:0005294,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015191,GO:0015238,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015821,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043200,GO:0043865,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:1901680,GO:1901682,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K03757,ko:K03759,ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13,2.A.3.2	-	-	AA_permease_2
k59_48081_2	1379698.RBG1_1C00001G1725	1.67e-74	249.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
k59_83349_1	98439.AJLL01000047_gene2888	5.84e-84	262.0	2DB98@1|root,2Z7VA@2|Bacteria,1G05J@1117|Cyanobacteria,1JHH9@1189|Stigonemataceae	1117|Cyanobacteria	P	Photosystem II protein	psbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_42373_1	246197.MXAN_7065	8.2e-10	62.4	2EYPS@1|root,33RX8@2|Bacteria,1Q1IB@1224|Proteobacteria,437A6@68525|delta/epsilon subdivisions,2X3Z9@28221|Deltaproteobacteria,2YXP1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42373_2	243231.GSU2816	8.27e-31	122.0	COG2204@1|root,COG4191@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_89180_1	619693.HMPREF6745_2649	1.51e-35	135.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,2FPHH@200643|Bacteroidia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_77505_1	1121396.KB893080_gene898	2.16e-40	150.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2WU4G@28221|Deltaproteobacteria,2MMQM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_130301_1	1304877.KI519399_gene4122	1.43e-45	156.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria,3JVRP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.103,4.1.1.46	ko:K07045,ko:K14333,ko:K15063,ko:K20941	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821,R09278,R11353	RC00390,RC00569	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
k59_95159_1	706587.Desti_4540	1.32e-82	246.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria,2MSK6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_177371_1	6087.XP_002168505.2	5.75e-05	49.7	COG0515@1|root,KOG4250@2759|Eukaryota	2759|Eukaryota	KLT	IkappaB kinase activity	IKK1	GO:0001666,GO:0002225,GO:0002230,GO:0002252,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006963,GO:0007154,GO:0007165,GO:0007166,GO:0007249,GO:0007252,GO:0008063,GO:0008150,GO:0008152,GO:0008384,GO:0008385,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009615,GO:0009617,GO:0009628,GO:0009653,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019221,GO:0019222,GO:0019538,GO:0019730,GO:0019731,GO:0023051,GO:0023052,GO:0023057,GO:0030163,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0032502,GO:0032991,GO:0033209,GO:0033554,GO:0034097,GO:0034248,GO:0034250,GO:0034612,GO:0035556,GO:0036211,GO:0036293,GO:0036294,GO:0042221,GO:0042742,GO:0043170,GO:0043207,GO:0043412,GO:0043900,GO:0043902,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045088,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048856,GO:0050688,GO:0050691,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050829,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0061057,GO:0061695,GO:0065007,GO:0065009,GO:0070482,GO:0070887,GO:0071310,GO:0071345,GO:0071356,GO:0071453,GO:0071456,GO:0071704,GO:0080090,GO:0080134,GO:0098542,GO:0140096,GO:1900424,GO:1900426,GO:1901222,GO:1901223,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1902531,GO:1902532,GO:1902554,GO:1902680,GO:1902911,GO:1903506,GO:1903508,GO:1990234,GO:2000112,GO:2001141	2.7.11.10	ko:K04467,ko:K07209	ko01523,ko04010,ko04014,ko04062,ko04064,ko04068,ko04150,ko04151,ko04210,ko04380,ko04620,ko04621,ko04622,ko04623,ko04624,ko04657,ko04658,ko04659,ko04660,ko04662,ko04668,ko04722,ko04910,ko04920,ko04930,ko04931,ko04932,ko05120,ko05131,ko05142,ko05145,ko05160,ko05161,ko05162,ko05164,ko05165,ko05166,ko05167,ko05168,ko05169,ko05200,ko05206,ko05212,ko05215,ko05220,ko05221,ko05222,ko05418,map01523,map04010,map04014,map04062,map04064,map04068,map04150,map04151,map04210,map04380,map04620,map04621,map04622,map04623,map04624,map04657,map04658,map04659,map04660,map04662,map04668,map04722,map04910,map04920,map04930,map04931,map04932,map05120,map05131,map05142,map05145,map05160,map05161,map05162,map05164,map05165,map05166,map05167,map05168,map05169,map05200,map05206,map05212,map05215,map05220,map05221,map05222,map05418	M00686	-	-	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	Pkinase
k59_24764_1	1125725.HMPREF1325_1955	6.53e-46	162.0	COG1749@1|root,COG1749@2|Bacteria,2J5H4@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar hook protein flgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_106803_2	3988.XP_002534941.1	1.05e-119	353.0	COG2801@1|root,KOG0017@2759|Eukaryota,37TAQ@33090|Viridiplantae,3GDDG@35493|Streptophyta,4JUJN@91835|fabids	35493|Streptophyta	L	cytochrome c biogenesis	ccmFc	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	CcmF_C
k59_106803_3	4096.XP_009785897.1	3.95e-179	502.0	COG2801@1|root,KOG0017@2759|Eukaryota,37TAQ@33090|Viridiplantae,3GDDG@35493|Streptophyta,44MWH@71274|asterids	35493|Streptophyta	L	cellular component organization	ccmFc	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	CcmF_C
k59_106803_4	29730.Gorai.001G160200.1	0.0	1040.0	COG1138@1|root,2QQ5D@2759|Eukaryota,37KAN@33090|Viridiplantae,3G7VB@35493|Streptophyta	35493|Streptophyta	O	cytochrome c	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0017004,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_106803_8	29730.Gorai.013G213000.1	0.0	929.0	COG0056@1|root,KOG1353@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit alpha	atp1	-	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_106803_10	2711.XP_006494662.1	3.79e-189	551.0	KOG1844@1|root,KOG1844@2759|Eukaryota,37IEA@33090|Viridiplantae,3GBRB@35493|Streptophyta	35493|Streptophyta	S	PHD finger protein MALE	-	GO:0000003,GO:0000212,GO:0000226,GO:0000228,GO:0000280,GO:0000785,GO:0000790,GO:0000791,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005719,GO:0006323,GO:0006355,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007059,GO:0007060,GO:0007140,GO:0007275,GO:0007276,GO:0008134,GO:0008150,GO:0009555,GO:0009889,GO:0009987,GO:0010032,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030154,GO:0030261,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0033613,GO:0042393,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0045132,GO:0048229,GO:0048232,GO:0048235,GO:0048285,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0051321,GO:0051704,GO:0055046,GO:0060255,GO:0065007,GO:0070013,GO:0070192,GO:0071103,GO:0071840,GO:0080090,GO:0097159,GO:0098813,GO:0140013,GO:1901363,GO:1903046,GO:1903506,GO:1990188,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	PHD
k59_106803_11	161934.XP_010689687.1	4.47e-34	129.0	KOG1844@1|root,KOG1844@2759|Eukaryota,37IEA@33090|Viridiplantae,3GBRB@35493|Streptophyta	35493|Streptophyta	S	PHD finger protein MALE	-	-	-	-	-	-	-	-	-	-	-	-	PHD
k59_106803_13	3649.evm.model.supercontig_19.225	2.69e-36	134.0	28IM6@1|root,2QQY2@2759|Eukaryota,37SMT@33090|Viridiplantae,3GB2N@35493|Streptophyta,3HN3J@3699|Brassicales	35493|Streptophyta	G	Belongs to the glycosyl hydrolase 17 family	-	GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0009505,GO:0016020,GO:0016787,GO:0016798,GO:0030246,GO:0030247,GO:0030312,GO:0031224,GO:0031225,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0046658,GO:0071944	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
k59_106803_14	102107.XP_008237671.1	7.32e-11	63.2	COG0515@1|root,KOG1187@2759|Eukaryota,37PSM@33090|Viridiplantae,3GCKH@35493|Streptophyta,4JKI2@91835|fabids	35493|Streptophyta	T	L-type lectin-domain containing receptor kinase	-	GO:0002229,GO:0002239,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0016020,GO:0042742,GO:0043207,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0071944,GO:0098542	2.7.11.1	ko:K04733	ko04010,ko04064,ko04620,ko04621,ko04624,ko04722,ko05133,ko05140,ko05142,ko05145,ko05152,ko05162,ko05164,map04010,map04064,map04620,map04621,map04624,map04722,map05133,map05140,map05142,map05145,map05152,map05162,map05164	M00686	-	-	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	Lectin_legB,Pkinase,Pkinase_Tyr
k59_106803_15	4113.PGSC0003DMT400027412	5.14e-38	137.0	2CYCC@1|root,2S3JA@2759|Eukaryota,37W9K@33090|Viridiplantae,3GKAK@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_48115_1	440512.C211_20348	3.27e-30	121.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_54083_1	45351.EDO49837	4.78e-06	52.8	COG0666@1|root,KOG1710@2759|Eukaryota,39V6E@33154|Opisthokonta,3BAJ7@33208|Metazoa	33208|Metazoa	S	regulation of smoothened signaling pathway	ANKMY2	GO:0002119,GO:0002164,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005929,GO:0006950,GO:0006970,GO:0007275,GO:0007610,GO:0007635,GO:0008104,GO:0008150,GO:0008270,GO:0008589,GO:0009266,GO:0009628,GO:0009791,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0010752,GO:0010753,GO:0016043,GO:0019899,GO:0022607,GO:0022611,GO:0023051,GO:0023056,GO:0030030,GO:0030031,GO:0030033,GO:0032101,GO:0032501,GO:0032502,GO:0032528,GO:0033036,GO:0033365,GO:0034613,GO:0040012,GO:0040024,GO:0042221,GO:0042995,GO:0043054,GO:0043167,GO:0043169,GO:0043226,GO:0044085,GO:0044464,GO:0046662,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048581,GO:0048583,GO:0048584,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050896,GO:0050920,GO:0051093,GO:0051179,GO:0051239,GO:0051241,GO:0051641,GO:0061062,GO:0061064,GO:0061065,GO:0061067,GO:0061512,GO:0065007,GO:0070727,GO:0071840,GO:0071981,GO:0072657,GO:0097499,GO:0097500,GO:0097730,GO:0120025,GO:0120031,GO:0120036,GO:1902531,GO:1902533,GO:1903441,GO:1904106,GO:1904107,GO:1990778,GO:2000026,GO:2000241	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5,zf-MYND
k59_100991_1	679190.HMPREF0650_1792	1.62e-15	82.8	COG3209@1|root,COG3209@2|Bacteria,4NGJF@976|Bacteroidetes,2FQPQ@200643|Bacteroidia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,VCBS
k59_59908_1	5016.M2UA20	4.62e-06	47.8	COG1007@1|root,KOG4668@2759|Eukaryota,38F5W@33154|Opisthokonta,3NZK6@4751|Fungi,3R7Q5@4890|Ascomycota,20888@147541|Dothideomycetes,4KJ2R@92860|Pleosporales	4751|Fungi	C	LAGLIDADG endonuclease	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	LAGLIDADG_1,NADH5_C,Proton_antipo_M,Proton_antipo_N
k59_159808_1	1122605.KB893637_gene3206	7.17e-61	193.0	2CH4A@1|root,32I9G@2|Bacteria,4NQS8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12995_1	1379698.RBG1_1C00001G0340	1.46e-53	191.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
k59_101009_1	502025.Hoch_4438	1.51e-29	122.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_65906_1	278957.ABEA03000176_gene2860	8.68e-20	91.3	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,3K7YF@414999|Opitutae	414999|Opitutae	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_42422_1	293826.Amet_1047	1.34e-16	84.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia,36E38@31979|Clostridiaceae	186801|Clostridia	L	This gene contains a nucleotide ambiguity which may be the result of a sequencing error	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_159841_1	6087.XP_004207813.1	4.2e-33	139.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa	33208|Metazoa	J	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_177420_1	1162668.LFE_0875	2.9e-17	80.9	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_177420_2	1379698.RBG1_1C00001G1604	0.0	908.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_112704_1	98439.AJLL01000034_gene2883	6.85e-05	45.8	COG0283@1|root,COG0414@1|root,COG0283@2|Bacteria,COG0414@2|Bacteria,1G1BX@1117|Cyanobacteria,1JH2P@1189|Stigonemataceae	1117|Cyanobacteria	FH	Pantoate-beta-alanine ligase	panC/cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25,6.3.2.1	ko:K13799	ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110	M00052,M00119	R00158,R00512,R01665,R02473	RC00002,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,Pantoate_ligase
k59_48172_1	391038.Bphy_3728	2.42e-37	139.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2VM0Z@28216|Betaproteobacteria,1K0MP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_124642_1	391896.A1I_02360	1.11e-46	162.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_7821_2	1121288.AULL01000015_gene5	6.28e-05	49.3	COG1595@1|root,COG1595@2|Bacteria,4NM7R@976|Bacteroidetes,1I1GD@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_72247_1	7668.SPU_015562-tr	2.43e-57	210.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3E41I@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_101574_1	283166.BH10120	3.56e-73	244.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,48TTG@772|Bartonellaceae	28211|Alphaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_78173_1	3880.AES92422	6.79e-47	161.0	2D3ZV@1|root,2STDG@2759|Eukaryota,381AJ@33090|Viridiplantae,3GR1G@35493|Streptophyta,4JVF4@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78173_2	981085.XP_010088417.1	1.02e-36	135.0	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta,4JS2T@91835|fabids	35493|Streptophyta	C	Ribulose bisphosphate carboxylase, large chain	rbcL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.1.3.15,4.1.1.39,6.4.1.2	ko:K01601,ko:K01963	ko00061,ko00620,ko00630,ko00640,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00630,map00640,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00165,M00166,M00376,M00532	R00024,R00742,R03140,R04386	RC00040,RC00172,RC00253,RC00367,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_78173_3	981085.XP_010109403.1	3.21e-36	122.0	2D40V@1|root,2STG3@2759|Eukaryota,381GS@33090|Viridiplantae,3GMA3@35493|Streptophyta,4JUQW@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78173_4	218851.Aquca_064_00043.1	1.17e-28	103.0	2E8J1@1|root,2SF10@2759|Eukaryota,37XUZ@33090|Viridiplantae,3GMW1@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_48818_1	1453500.AT05_00180	0.000994	49.7	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_72248_1	8479.XP_008173082.1	5.82e-102	312.0	28HC0@1|root,2QPQD@2759|Eukaryota,39S4C@33154|Opisthokonta,3BMKF@33208|Metazoa,3D63M@33213|Bilateria,48BPK@7711|Chordata,495JJ@7742|Vertebrata,4CMFM@8459|Testudines	33208|Metazoa	S	ZnF_TTF	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_59368_1	1379698.RBG1_1C00001G0485	1.92e-69	223.0	COG2025@1|root,COG2025@2|Bacteria,2NNR6@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	fixB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	iAF987.Gmet_2066,iAF987.Gmet_2257	ETF,ETF_alpha,Fer4
k59_153221_1	7897.ENSLACP00000006934	0.000144	51.6	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa,3D0QV@33213|Bilateria,48CBX@7711|Chordata	33208|Metazoa	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_42540_1	909663.KI867150_gene2559	4.97e-33	115.0	COG1598@1|root,COG1598@2|Bacteria,1NDQJ@1224|Proteobacteria,42WAM@68525|delta/epsilon subdivisions,2WRR1@28221|Deltaproteobacteria,2MSC3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
k59_18760_1	1499967.BAYZ01000176_gene5645	5.26e-74	236.0	COG3872@1|root,COG3872@2|Bacteria,2NP59@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1385)	prmC	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
k59_48288_1	873513.HMPREF6485_0165	1.23e-75	253.0	COG1629@1|root,COG4771@2|Bacteria,4NIUN@976|Bacteroidetes,2FPXH@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_13147_1	1121377.KB906399_gene1747	1.66e-27	114.0	COG0169@1|root,COG0169@2|Bacteria,1WIM8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_18763_2	1284686.HMPREF1630_04785	3.67e-09	58.2	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,22HF7@1570339|Peptoniphilaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_60058_1	1089550.ATTH01000001_gene1641	4.11e-35	131.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,1FJ83@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	CcmB protein	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
k59_71720_2	234267.Acid_3576	2.07e-09	60.1	COG1600@1|root,COG1600@2|Bacteria,3Y3TQ@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_83546_1	7668.SPU_005181-tr	3.53e-49	177.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,RVT_1
k59_54250_1	498761.HM1_2261	3.23e-37	132.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_54253_1	575594.ACOH01000002_gene1089	1.53e-22	101.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,3F44K@33958|Lactobacillaceae	91061|Bacilli	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_30811_1	34506.g6429	5.65e-09	65.1	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,40QW0@6231|Nematoda,1M0K4@119089|Chromadorea,41714@6236|Rhabditida	33208|Metazoa	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_77720_1	65093.PCC7418_2895	7.83e-16	82.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria	1117|Cyanobacteria	K	ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_60074_1	1089553.Tph_c10260	1.59e-58	189.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,42ET2@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_66082_1	10224.XP_006819135.1	2.82e-61	213.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_153935_1	1121440.AUMA01000007_gene1202	2.18e-21	96.7	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria,2M7VW@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_1386_1	945713.IALB_2662	3.37e-28	124.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
k59_42573_1	411476.BACOVA_04794	7.51e-48	167.0	COG0863@1|root,COG0863@2|Bacteria,4NF6R@976|Bacteroidetes	976|Bacteroidetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_42574_1	1423724.BAMM01000001_gene280	3.53e-28	112.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae	91061|Bacilli	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_177571_1	278963.ATWD01000001_gene2116	2.18e-21	92.4	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_25011_1	247490.KSU1_C0981	7.24e-21	100.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_30829_2	172088.AUGA01000003_gene5608	2.17e-28	116.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,3JRE0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_118982_1	7719.XP_002124374.1	6.5e-32	126.0	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa,3D0QV@33213|Bilateria,48CBX@7711|Chordata	33208|Metazoa	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_166033_2	1379698.RBG1_1C00001G1066	8.47e-07	50.1	COG0260@1|root,COG0260@2|Bacteria,2NNKH@2323|unclassified Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1,3.4.11.5	ko:K01255,ko:K01259	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00135,R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_118989_1	1444711.CCJF01000004_gene2293	9.57e-36	130.0	COG0356@1|root,COG0356@2|Bacteria,2JFFC@204428|Chlamydiae	204428|Chlamydiae	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_118989_2	1444711.CCJF01000004_gene2294	4.32e-25	95.5	COG0636@1|root,COG0636@2|Bacteria,2JGFR@204428|Chlamydiae	204428|Chlamydiae	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_60102_1	6412.HelroP179128	9.04e-24	107.0	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa,3E5DG@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_71764_1	1294143.H681_04400	2.45e-28	119.0	COG3093@1|root,COG3093@2|Bacteria,1MV9M@1224|Proteobacteria,1RNP6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	growth	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130554_1	1121289.JHVL01000037_gene3044	1.35e-14	80.9	COG1129@1|root,COG4720@1|root,COG1129@2|Bacteria,COG4720@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,36UGY@31979|Clostridiaceae	186801|Clostridia	G	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS
k59_107028_1	1192034.CAP_3405	2.08e-83	272.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2YUN3@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_60111_1	335543.Sfum_1150	7.09e-69	220.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MQS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_124791_2	215803.DB30_2742	7.84e-38	133.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,2YVX9@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k59_160092_1	7222.FBpp0155933	2.89e-08	62.0	KOG0650@1|root,KOG0650@2759|Eukaryota,38DR5@33154|Opisthokonta,3BEY3@33208|Metazoa,3CTES@33213|Bilateria,41VAQ@6656|Arthropoda,3SJ4C@50557|Insecta,452DK@7147|Diptera,45T7M@7214|Drosophilidae	33208|Metazoa	A	Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit	BOP1	GO:0000027,GO:0000448,GO:0000460,GO:0000463,GO:0000466,GO:0000469,GO:0000470,GO:0000478,GO:0000479,GO:0002682,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008283,GO:0009966,GO:0009987,GO:0010467,GO:0010646,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0023051,GO:0030684,GO:0030686,GO:0030687,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0035206,GO:0042127,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0044877,GO:0046483,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051239,GO:0051726,GO:0065003,GO:0065007,GO:0070013,GO:0070545,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901796,GO:1902531,GO:1990904	-	ko:K14824	-	-	-	-	ko00000,ko03009	-	-	-	BOP1NT,WD40
k59_148187_2	1385519.N801_15600	2.1e-08	57.8	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4FEGB@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_119018_2	760192.Halhy_0561	6.57e-28	107.0	2CM52@1|root,30ZNE@2|Bacteria,4NP1A@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 9.46	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83608_1	6087.XP_002168109.2	6.95e-14	80.1	COG0659@1|root,KOG0236@2759|Eukaryota,38EAT@33154|Opisthokonta,3BAAN@33208|Metazoa	33208|Metazoa	P	secondary active sulfate transmembrane transporter activity	-	GO:0003674,GO:0005215,GO:0005216,GO:0005253,GO:0005254,GO:0005310,GO:0005342,GO:0005452,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006820,GO:0006821,GO:0006835,GO:0006855,GO:0006873,GO:0006885,GO:0008028,GO:0008150,GO:0008272,GO:0008324,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015085,GO:0015103,GO:0015106,GO:0015108,GO:0015116,GO:0015238,GO:0015267,GO:0015291,GO:0015297,GO:0015301,GO:0015318,GO:0015499,GO:0015698,GO:0015701,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0019531,GO:0019532,GO:0019725,GO:0022803,GO:0022804,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042391,GO:0042493,GO:0042592,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070588,GO:0070838,GO:0071702,GO:0071944,GO:0072348,GO:0072511,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:0098771,GO:0099516,GO:1901682,GO:1902358,GO:1902476,GO:1903825,GO:1905039	-	ko:K14453	-	-	-	-	ko00000,ko02000	2.A.53.2	-	-	STAS,Sulfate_transp
k59_7416_16	582744.Msip34_1657	6.26e-40	135.0	28X0R@1|root,2ZIZK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154100_1	1519464.HY22_02495	0.000129	44.3	COG1138@1|root,COG1138@2|Bacteria,1FEUA@1090|Chlorobi	1090|Chlorobi	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_154100_2	1123242.JH636435_gene2774	5.99e-27	105.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yxeL	-	-	ko:K00680	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
k59_48457_1	269799.Gmet_3487	3.15e-12	68.9	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2WRW0@28221|Deltaproteobacteria,43TY1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YkuD
k59_48457_2	484018.BACPLE_03758	1.01e-11	66.6	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NGKF@976|Bacteroidetes,2FQ8I@200643|Bacteroidia,4APSR@815|Bacteroidaceae	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_148283_1	886293.Sinac_3666	1.12e-61	212.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2IXNQ@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase, iron-sulfur binding subunit	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
k59_101289_1	1121930.AQXG01000002_gene2132	2.53e-13	79.3	COG1520@1|root,COG1520@2|Bacteria,4P78D@976|Bacteroidetes,1J10I@117747|Sphingobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_112930_1	868595.Desca_1434	9.02e-14	72.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,266TP@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_66236_1	261292.Nit79A3_0156	1.48e-33	132.0	COG3385@1|root,COG3385@2|Bacteria,1RA6A@1224|Proteobacteria,2VUMQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_77860_1	1265505.ATUG01000002_gene2801	1.2e-127	376.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2MHYU@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_60207_1	72664.XP_006392407.1	1.2e-60	204.0	2D3IU@1|root,2SRQQ@2759|Eukaryota,381NS@33090|Viridiplantae,3GQYF@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Retrotrans_gag
k59_7434_1	398767.Glov_0402	2.22e-05	51.6	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RI33@1224|Proteobacteria,42SUG@68525|delta/epsilon subdivisions,2WP3A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	bamV	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
k59_42721_1	1380391.JIAS01000011_gene5133	1.2e-37	150.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2JQ2C@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_83718_2	319225.Plut_1891	5.67e-20	87.4	COG0671@1|root,COG0671@2|Bacteria,1FFMA@1090|Chlorobi	1090|Chlorobi	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_48466_1	7070.TC012929-PA	4.06e-75	245.0	2CMVD@1|root,2QS6T@2759|Eukaryota,38ITZ@33154|Opisthokonta,3BGFP@33208|Metazoa,3D162@33213|Bilateria,41U69@6656|Arthropoda,3SIX2@50557|Insecta	33208|Metazoa	S	DNA-binding transcription factor activity, RNA polymerase II-specific	EPM2AIP1	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_160282_1	1379698.RBG1_1C00001G1858	5.79e-11	64.3	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
k59_160282_2	1379698.RBG1_1C00001G1859	1.83e-19	90.1	COG3481@1|root,COG3481@2|Bacteria,2NPNP@2323|unclassified Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
k59_136697_1	7029.ACYPI22826-PA	4.93e-38	147.0	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa,3DKI7@33213|Bilateria,422A5@6656|Arthropoda,3SQP0@50557|Insecta	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_60212_1	358220.C380_09405	2.89e-55	196.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4A9T5@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_2	-	-	ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
k59_18936_1	644282.Deba_1864	1.08e-92	285.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_54434_1	1131812.JQMS01000001_gene806	6.75e-08	60.8	COG0642@1|root,COG3829@1|root,COG4191@1|root,COG5000@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,4PD3B@976|Bacteroidetes,1INA1@117743|Flavobacteriia,2NYQP@237|Flavobacterium	976|Bacteroidetes	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,PAS,PAS_9
k59_142310_5	6412.HelroP113270	6.69e-25	95.5	COG1005@1|root,KOG4770@2759|Eukaryota,3ASV9@33154|Opisthokonta,3C4G2@33208|Metazoa,3DJNX@33213|Bilateria	33208|Metazoa	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K03878	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_142310_8	13616.ENSMODP00000026932	0.000537	47.0	COG1007@1|root,KOG4668@2759|Eukaryota,3940U@33154|Opisthokonta,3BFHH@33208|Metazoa,3D425@33213|Bilateria,4882A@7711|Chordata,496FV@7742|Vertebrata,3JA26@40674|Mammalia,4K7NI@9263|Metatheria	33208|Metazoa	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	ND2	GO:0003674,GO:0003824,GO:0003954,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010257,GO:0014069,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032279,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0035254,GO:0035255,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044456,GO:0044464,GO:0045202,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0072593,GO:0097458,GO:0098794,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0098984,GO:0099572,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADH_dehy_S2_C,Proton_antipo_M
k59_95637_1	1129374.AJE_08527	7.24e-15	73.6	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1PFUN@1224|Proteobacteria,1RR40@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
k59_95637_2	1129374.AJE_08532	5.13e-56	179.0	COG1487@1|root,COG1487@2|Bacteria,1RCQ1@1224|Proteobacteria,1S2N6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
k59_177808_1	400682.PAC_15725533	5.57e-34	131.0	2CXTH@1|root,2RZKM@2759|Eukaryota,3A38H@33154|Opisthokonta,3BQSZ@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
k59_7456_1	264462.Bd2462	1.01e-16	82.8	COG0741@1|root,COG0741@2|Bacteria,1N1GB@1224|Proteobacteria,42X1K@68525|delta/epsilon subdivisions,2MTCK@213481|Bdellovibrionales,2WTCI@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_1546_1	880073.Calab_0674	3.29e-106	347.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
k59_142316_1	1123242.JH636435_gene2085	1.19e-17	87.4	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,2IY2P@203682|Planctomycetes	203682|Planctomycetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_160298_1	7668.SPU_011060-tr	2.42e-69	227.0	28N8N@1|root,2QUTZ@2759|Eukaryota,39XUZ@33154|Opisthokonta,3BIC8@33208|Metazoa,3D1M8@33213|Bilateria	33208|Metazoa	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_Tnp_Tc3_2
k59_119173_1	756272.Plabr_4674	3.66e-105	320.0	COG0843@1|root,COG0843@2|Bacteria,2IXCQ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_124951_1	1089550.ATTH01000001_gene1640	1.2e-05	53.1	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1FIKF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
k59_77896_1	316067.Geob_1371	2.36e-26	110.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_66298_1	58123.JOFJ01000004_gene1855	1.23e-52	180.0	COG0438@1|root,COG0438@2|Bacteria,2GMR9@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_37066_2	1379698.RBG1_1C00001G1870	2.37e-33	125.0	COG0232@1|root,COG0232@2|Bacteria,2NP3S@2323|unclassified Bacteria	2|Bacteria	F	Phosphohydrolase-associated domain	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_171788_1	7739.XP_002599919.1	1.88e-11	60.5	28MKJ@1|root,2QU48@2759|Eukaryota,392MY@33154|Opisthokonta,3BGCT@33208|Metazoa,3D2GR@33213|Bilateria,488VI@7711|Chordata	33208|Metazoa	S	scavenger receptor activity	LGALS3BP	GO:0002576,GO:0003674,GO:0005044,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0006897,GO:0006898,GO:0006950,GO:0006952,GO:0006968,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0012505,GO:0016192,GO:0023052,GO:0030141,GO:0031089,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0038024,GO:0042827,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0060205,GO:0065007,GO:0070013,GO:0097708,GO:0098657,GO:0099503	-	ko:K17300	-	-	-	-	ko00000,ko04147	-	-	-	BACK,BTB,SRCR
k59_138487_1	357804.Ping_0065	1.36e-07	52.8	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,2QHEC@267894|Psychromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_120961_1	7425.NV20563-PA	1.14e-06	57.4	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RNase_H,RVT_1
k59_91333_1	7668.SPU_016918-tr	1.65e-31	129.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_114326_2	1463921.JODF01000003_gene2356	2.52e-98	306.0	COG4653@1|root,COG4653@2|Bacteria,2ICZP@201174|Actinobacteria	201174|Actinobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_capsid
k59_44342_1	765913.ThidrDRAFT_4206	1.4e-22	102.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,1S0E6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_44342_2	1442598.JABW01000027_gene913	2.43e-31	122.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,42P8F@68525|delta/epsilon subdivisions,2YN1C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cytidylyltransferase	ptmB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_73832_1	926692.AZYG01000029_gene1622	5.59e-80	251.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3WABP@53433|Halanaerobiales	186801|Clostridia	J	class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_3458_1	1123354.AUDR01000017_gene34	1.93e-56	191.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,1KS80@119069|Hydrogenophilales	119069|Hydrogenophilales	M	MraW methylase family	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_3458_2	886379.AEWI01000018_gene1274	5.81e-07	52.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,2FUA3@200643|Bacteroidia,3XK4Z@558415|Marinilabiliaceae	976|Bacteroidetes	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_73833_1	997296.PB1_13784	3.34e-89	286.0	COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus	91061|Bacilli	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
k59_56342_2	401053.AciPR4_3686	2.59e-41	144.0	COG1028@1|root,COG1028@2|Bacteria,3Y3FQ@57723|Acidobacteria,2JHPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_103048_1	218851.Aquca_023_00090.1	2.38e-21	99.0	28ZYQ@1|root,2R6TI@2759|Eukaryota,37R3C@33090|Viridiplantae,3GH9I@35493|Streptophyta	35493|Streptophyta	L	DNA-directed DNA polymerase activity	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2
k59_91347_1	3712.Bo2g060030.1	1.83e-35	138.0	COG5186@1|root,KOG2245@2759|Eukaryota	2759|Eukaryota	A	polynucleotide adenylyltransferase activity	-	GO:0003674,GO:0003824,GO:0004652,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005847,GO:0005849,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043631,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0070013,GO:0070566,GO:0071704,GO:0090304,GO:1901360	2.7.7.19	ko:K09254,ko:K14376	ko03015,ko04014,ko04624,ko05202,ko05203,map03015,map04014,map04624,map05202,map05203	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03019	-	-	-	NTP_transf_2,PAP_RNA-bind,PAP_central
k59_120974_1	552396.HMPREF0863_00269	6.66e-11	68.2	COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes	1239|Firmicutes	D	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,Sipho_tail
k59_20575_2	1125863.JAFN01000001_gene1054	0.000513	42.7	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
k59_144405_1	1449126.JQKL01000031_gene1133	4.17e-06	47.8	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,267KG@186813|unclassified Clostridiales	186801|Clostridia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
k59_68202_1	555779.Dthio_PD3761	1.29e-46	154.0	COG1569@1|root,COG1569@2|Bacteria,1Q9X8@1224|Proteobacteria,431MF@68525|delta/epsilon subdivisions,2WWQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_179855_1	7029.ACYPI42931-PA	4.66e-11	71.2	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa,3D0QV@33213|Bilateria	7029.ACYPI42931-PA|-	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_168145_1	1457393.AZ09_05990	1.94e-07	56.6	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,2JRAI@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class-V	-	-	2.6.1.112	ko:K00839	ko00230,map00230	-	R10908	RC00018,RC03305	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
k59_109171_1	1379698.RBG1_1C00001G0777	4.96e-103	325.0	COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
k59_120982_1	323259.Mhun_1500	1.2e-21	93.6	COG1683@1|root,arCOG04848@2157|Archaea,2XV91@28890|Euryarchaeota,2NANV@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_73841_1	1499967.BAYZ01000148_gene1760	4.25e-24	105.0	COG0771@1|root,COG0771@2|Bacteria,2NPCH@2323|unclassified Bacteria	2|Bacteria	M	Mur ligase middle domain	murD	-	6.3.2.9	ko:K01925,ko:K01932	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_73841_2	1211115.ALIQ01000036_gene1893	5.15e-06	50.8	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,3NAAD@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_15392_1	1232437.KL662030_gene2460	2.87e-37	134.0	2C5Z2@1|root,32U5Z@2|Bacteria,1N4MT@1224|Proteobacteria,42TX0@68525|delta/epsilon subdivisions,2WQZM@28221|Deltaproteobacteria,2MKYF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
k59_155854_1	1453500.AT05_04760	2.72e-11	65.1	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
k59_168155_1	494416.AYXN01000037_gene833	2.56e-24	93.2	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,3NPC2@468|Moraxellaceae	1236|Gammaproteobacteria	K	'Cold-shock' DNA-binding domain	capB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_173473_1	324602.Caur_1424	1.02e-71	229.0	COG0524@1|root,COG0524@2|Bacteria,2GAA6@200795|Chloroflexi,376QU@32061|Chloroflexia	32061|Chloroflexia	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k59_173473_2	867845.KI911784_gene1479	1.44e-18	83.6	COG0558@1|root,COG0558@2|Bacteria,2GAQW@200795|Chloroflexi,3773G@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_103061_2	6412.HelroP170806	2.52e-155	462.0	2FAER@1|root,2TBMF@2759|Eukaryota,3AN09@33154|Opisthokonta,3C1R4@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150408_1	1396418.BATQ01000141_gene3408	0.000615	48.9	COG1680@1|root,COG1680@2|Bacteria,46T7M@74201|Verrucomicrobia,2IWEF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_150408_2	1501230.ET33_09220	4.9e-14	68.6	COG0454@1|root,COG0456@2|Bacteria,1V50M@1239|Firmicutes,4HH63@91061|Bacilli,26XZ2@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	yqjY	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K06977	-	-	-	-	ko00000	-	-	-	Acetyltransf_1
k59_120997_1	218284.CCDN010000005_gene3214	4.7e-53	183.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus	91061|Bacilli	O	Peptidase M48	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_155870_1	1379698.RBG1_1C00001G0529	2.36e-50	174.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_61983_2	1379698.RBG1_1C00001G0119	4.1e-48	166.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68231_1	1444306.JFZC01000012_gene2013	1.15e-12	72.0	COG0388@1|root,COG0388@2|Bacteria,1V4HM@1239|Firmicutes,4IQ6E@91061|Bacilli	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_138505_1	7029.ACYPI30841-PA	1.23e-93	331.0	2CY1J@1|root,2S1BE@2759|Eukaryota,3A4Q6@33154|Opisthokonta,3BRW8@33208|Metazoa,3D9KI@33213|Bilateria,422F1@6656|Arthropoda	33208|Metazoa	O	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	MULE,Prok-RING_4,Tnp_P_element,zf-C3HC4_3
k59_27229_1	3847.GLYMA12G36150.1	9.7e-27	110.0	2CMAK@1|root,2QPT8@2759|Eukaryota,37MKA@33090|Viridiplantae,3GD5I@35493|Streptophyta,4JKHT@91835|fabids	35493|Streptophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N,CemA
k59_127530_1	497321.C664_19941	1.12e-50	177.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,2VMEU@28216|Betaproteobacteria,2KYGD@206389|Rhodocyclales	206389|Rhodocyclales	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_39450_1	404589.Anae109_1972	4.89e-31	121.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42Z0A@68525|delta/epsilon subdivisions,2WUAC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_39450_2	1348662.CARG_05570	0.000116	44.3	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,22JKK@1653|Corynebacteriaceae	201174|Actinobacteria	GK	polyphosphate glucokinase	ppgK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0040007,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0047330,GO:0051156,GO:0071704,GO:1901135	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_33687_2	983328.AFGH01000002_gene1302	5.26e-21	87.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2YQEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_151269_1	1519464.HY22_02715	2.67e-84	282.0	COG1196@1|root,COG1196@2|Bacteria,1FDPC@1090|Chlorobi	1090|Chlorobi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_86611_1	1454004.AW11_03331	2.41e-51	180.0	COG1226@1|root,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria	1224|Proteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_121866_1	1519464.HY22_02805	3.49e-73	248.0	COG0653@1|root,COG0653@2|Bacteria,1FDBP@1090|Chlorobi	1090|Chlorobi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_115220_1	3847.GLYMA13G11958.1	1.07e-18	82.8	2B1MW@1|root,2S0AS@2759|Eukaryota,37V2H@33090|Viridiplantae,3GQER@35493|Streptophyta,4JUTK@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10184_1	1379698.RBG1_1C00001G0326	6.23e-141	419.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
k59_50670_1	7897.ENSLACP00000010148	9.29e-27	117.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,487FB@7711|Chordata,491IP@7742|Vertebrata	33208|Metazoa	-	-	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_121872_2	7668.SPU_008007-tr	5.12e-46	178.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_92302_1	1379698.RBG1_1C00001G0312	3.47e-111	330.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_186242_1	31234.CRE26771	2.06e-43	157.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_110079_1	1042163.BRLA_c032100	2.32e-33	132.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,26SWP@186822|Paenibacillaceae	91061|Bacilli	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_156770_1	671143.DAMO_2962	1.7e-72	234.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_133473_1	522306.CAP2UW1_3158	8.72e-135	401.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,2VP7Z@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,HTH_Tnp_Mu_1,Mu-transpos_C,rve
k59_133473_2	522306.CAP2UW1_3159	2.18e-114	337.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_163241_1	5147.XP_003342404.1	4.27e-11	67.8	2CHWR@1|root,2RAQ0@2759|Eukaryota,3ADN6@33154|Opisthokonta,3P9VB@4751|Fungi,3RIA1@4890|Ascomycota,21GAX@147550|Sordariomycetes	4751|Fungi	S	WGS project CABT00000000 data, contig 2.1583	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
k59_4480_1	1379698.RBG1_1C00001G0568	4.22e-106	321.0	COG1109@1|root,COG1109@2|Bacteria,2NNRE@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iECS88_1305.ECS88_2145,iECUMN_1333.ECUMN_2384,iUTI89_1310.UTI89_C2321	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_57348_1	1121377.KB906398_gene2482	1.36e-114	358.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_86648_1	639283.Snov_4211	9.51e-33	127.0	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,2TQYT@28211|Alphaproteobacteria,3EY7E@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Phosphate acetyl/butaryl transferase	pta	-	2.3.1.19,2.3.1.8	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921,R01174	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
k59_133474_2	7029.ACYPI066123-PA	1.83e-68	243.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39MWR@33154|Opisthokonta,3CPGB@33208|Metazoa,3E5ME@33213|Bilateria	2759|Eukaryota	S	Domain of unknown function (DUF4371)	-	-	-	ko:K06515	ko05231,map05231	-	-	-	ko00000,ko00001,ko02000,ko04090	2.A.92.1.1	-	-	Dimer_Tnp_hAT,Exo_endo_phos_2,PRE_C2HC,RVT_1
k59_33732_2	765420.OSCT_0999	5.88e-07	55.5	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
k59_145458_2	391615.ABSJ01000043_gene2317	3.06e-15	75.1	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1J53F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_69177_1	1191523.MROS_1617	1.57e-20	94.4	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_39774_1	1379698.RBG1_1C00001G0733	5.01e-19	92.8	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169122_2	762984.HMPREF9445_00228	0.000925	45.8	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,2G3F5@200643|Bacteroidia,4AM87@815|Bacteroidaceae	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_156786_1	7668.SPU_025111-tr	9.58e-81	263.0	28M7P@1|root,2QTQS@2759|Eukaryota,39Z9X@33154|Opisthokonta,3BNGS@33208|Metazoa,3D442@33213|Bilateria	33208|Metazoa	S	cellular response to interferon-beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115272_1	1123256.KB907925_gene1043	1.63e-06	50.1	arCOG07533@1|root,2ZF5I@2|Bacteria,1RB8D@1224|Proteobacteria,1SBRH@1236|Gammaproteobacteria,1X79G@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
k59_115272_3	869209.Tresu_1693	2.8e-68	211.0	2FE6T@1|root,3466M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_121925_1	383372.Rcas_3883	1.17e-10	65.5	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,2G7PG@200795|Chloroflexi	200795|Chloroflexi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM,PAS_3,PAS_4,Response_reg
k59_80838_3	309799.DICTH_1434	4.19e-33	127.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k59_39782_2	1122962.AULH01000013_gene529	3.74e-11	62.4	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k59_151330_1	330214.NIDE2040	2.95e-67	219.0	COG0147@1|root,COG0147@2|Bacteria,3J0FG@40117|Nitrospirae	40117|Nitrospirae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_151330_2	1307437.J139_12678	0.000323	42.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,2Q1DJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	pabA	GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135	GATase
k59_69189_2	1173264.KI913949_gene2050	4.92e-28	113.0	2DBFF@1|root,2Z8YA@2|Bacteria,1G2KB@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_74814_1	8083.ENSXMAP00000005242	1.28e-06	55.5	29BXC@1|root,2RJ0S@2759|Eukaryota,39TVF@33154|Opisthokonta,3BJHD@33208|Metazoa,3D3GJ@33213|Bilateria,48CA5@7711|Chordata,493QF@7742|Vertebrata,49VEW@7898|Actinopterygii	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_127879_1	316274.Haur_0876	1.68e-16	77.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
k59_163281_1	102107.XP_008243956.1	5.59e-68	220.0	COG0473@1|root,KOG0785@2759|Eukaryota,37KMU@33090|Viridiplantae,3G86Y@35493|Streptophyta,4JGYG@91835|fabids	35493|Streptophyta	E	Isocitrate dehydrogenase (NAD	-	GO:0000166,GO:0003674,GO:0003824,GO:0004448,GO:0004449,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006102,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009507,GO:0009536,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_39804_1	635013.TherJR_1205	2.58e-45	167.0	COG0514@1|root,COG0608@1|root,COG0514@2|Bacteria,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
k59_57389_1	234621.RER_12380	7.15e-15	79.3	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4FV6F@85025|Nocardiaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_127886_2	7897.ENSLACP00000014653	1.45e-40	152.0	29Q9H@1|root,2RX81@2759|Eukaryota,39ZQJ@33154|Opisthokonta,3BNMR@33208|Metazoa,3D7EF@33213|Bilateria	33208|Metazoa	-	-	-	-	-	ko:K20283	-	-	-	-	ko00000,ko04131	-	-	-	-
k59_133512_1	7668.SPU_017677-tr	3.52e-18	92.8	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3C1BS@33208|Metazoa,3DJ0V@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_34431_1	760568.Desku_1018	3.44e-16	79.7	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia,2627T@186807|Peptococcaceae	186801|Clostridia	NT	Methyltransferase, chemotaxis proteins	cheR2	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_34431_2	933262.AXAM01000073_gene3357	3.17e-16	80.5	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MHS0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
k59_81634_1	1192034.CAP_2129	7.61e-42	144.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2YVC1@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_81634_2	518766.Rmar_1268	7.01e-06	49.3	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1FIPP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_75081_1	237368.SCABRO_01247	1.27e-42	147.0	COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_28274_1	316067.Geob_0072	4.56e-50	191.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_104123_1	760192.Halhy_0007	2.05e-70	228.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_39983_1	570967.JMLV01000006_gene206	2.78e-49	166.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_10494_1	457415.HMPREF1006_00819	1.41e-06	48.9	COG0759@1|root,COG0759@2|Bacteria,3TBI4@508458|Synergistetes	508458|Synergistetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_10494_2	1500301.JQMF01000001_gene394	0.00028	45.4	COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,4BEE6@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_151544_1	572544.Ilyop_0632	1.56e-42	158.0	COG1164@1|root,COG1164@2|Bacteria,378MH@32066|Fusobacteria	32066|Fusobacteria	E	Psort location Cytoplasmic, score	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_99141_1	130081.XP_005704990.1	6.46e-31	121.0	28ISP@1|root,2QR3X@2759|Eukaryota	2759|Eukaryota	S	photosynthetic electron transport in photosystem II	psbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009521,GO:0009523,GO:0009532,GO:0009533,GO:0009534,GO:0009535,GO:0009536,GO:0009539,GO:0009570,GO:0009579,GO:0010287,GO:0016020,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0098796	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII,Photo_RC
k59_110344_1	6087.XP_004208451.1	1.25e-32	127.0	KOG1121@1|root,KOG1121@2759|Eukaryota,38HW4@33154|Opisthokonta,3BBP7@33208|Metazoa	33208|Metazoa	L	zinc finger BED domain-containing protein	-	GO:0000976,GO:0000977,GO:0001012,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,zf-BED
k59_57592_1	7668.SPU_019679-tr	7.99e-57	196.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3B9WN@33208|Metazoa,3D1S8@33213|Bilateria	33208|Metazoa	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_21899_1	555779.Dthio_PD2271	1.33e-77	236.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,42THA@68525|delta/epsilon subdivisions,2WNG6@28221|Deltaproteobacteria,2MGHI@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_45627_1	1227457.C451_03814	2.03e-13	73.9	COG3385@1|root,arCOG06380@2157|Archaea	2157|Archaea	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57605_2	1379698.RBG1_1C00001G0118	4.1e-38	135.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169440_1	10224.XP_006822643.1	3.97e-19	92.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A4K9@33154|Opisthokonta,3BSC4@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_75137_1	204669.Acid345_2792	2.41e-123	380.0	COG2609@1|root,COG2609@2|Bacteria,3Y2M3@57723|Acidobacteria,2JHM5@204432|Acidobacteriia	204432|Acidobacteriia	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_128130_1	880072.Desac_0515	4.83e-27	107.0	COG0535@1|root,COG0535@2|Bacteria,1RCZX@1224|Proteobacteria,42RV6@68525|delta/epsilon subdivisions,2WNNU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_128130_2	933262.AXAM01000033_gene1636	1.9e-26	100.0	COG1342@1|root,COG1342@2|Bacteria,1N80T@1224|Proteobacteria,42S0E@68525|delta/epsilon subdivisions,2WNRK@28221|Deltaproteobacteria,2MJXG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function  DUF134	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
k59_10531_1	1123252.ATZF01000002_gene2616	0.000285	43.9	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,27BHU@186824|Thermoactinomycetaceae	91061|Bacilli	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_10531_2	997346.HMPREF9374_0699	8.33e-18	79.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,27C3I@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosome-binding factor A	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_10531_3	795359.TOPB45_1079	1.79e-40	150.0	COG0532@1|root,COG0532@2|Bacteria,2GGT0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_75148_1	1034347.CAHJ01000039_gene4783	9.2e-33	128.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,1ZCU1@1386|Bacillus	91061|Bacilli	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
k59_50964_1	1379698.RBG1_1C00001G0983	5.04e-55	189.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_99177_1	1041930.Mtc_2235	3.04e-18	89.4	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota,2N9BJ@224756|Methanomicrobia	224756|Methanomicrobia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	aor-2	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_63235_1	1304885.AUEY01000104_gene2548	7.89e-32	119.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
k59_69513_1	1282876.BAOK01000001_gene3642	1.64e-84	262.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_92678_2	6087.XP_004210714.1	4.2e-14	73.2	KOG1121@1|root,KOG1121@2759|Eukaryota,3A1BV@33154|Opisthokonta,3BQ1H@33208|Metazoa	33208|Metazoa	L	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,zf-BED
k59_163587_1	684949.ATTJ01000001_gene1781	2.34e-22	102.0	COG3501@1|root,COG3501@2|Bacteria	2|Bacteria	T	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k59_21943_1	7029.ACYPI000314-PA	6.31e-36	140.0	COG2801@1|root,KOG0017@2759|Eukaryota,3ABZJ@33154|Opisthokonta,3CPEU@33208|Metazoa,3E5JW@33213|Bilateria,42AMJ@6656|Arthropoda	7029.ACYPI000314-PA|-	L	Domain of unknown function (DUF4806)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_16809_1	400682.PAC_15704449	8.76e-19	97.8	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3C1BS@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_163601_1	861299.J421_6317	1.42e-13	70.9	COG0577@1|root,COG0577@2|Bacteria	861299.J421_6317|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_163601_2	693986.MOC_2754	1.63e-07	55.1	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,1JSY3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k59_104182_1	7955.ENSDARP00000102180	2.22e-25	114.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK37@33208|Metazoa,3D4E3@33213|Bilateria,482YV@7711|Chordata,497RB@7742|Vertebrata,49S97@7898|Actinopterygii	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_28371_1	247490.KSU1_D0121	6.4e-125	369.0	COG0538@1|root,COG0538@2|Bacteria,2J51C@203682|Planctomycetes	203682|Planctomycetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
k59_63264_1	1131462.DCF50_p1939	4.62e-29	122.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,2611Y@186807|Peptococcaceae	186801|Clostridia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_157091_2	1122137.AQXF01000002_gene29	7.57e-06	49.7	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TVFK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
k59_63268_1	1254432.SCE1572_03670	1.79e-61	207.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YUQD@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_186584_1	7897.ENSLACP00000002583	1.11e-146	442.0	28IIP@1|root,2QQVP@2759|Eukaryota,39TA7@33154|Opisthokonta,3CNWS@33208|Metazoa,3D3DK@33213|Bilateria,48RTD@7711|Chordata,49GA3@7742|Vertebrata	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_28379_1	944479.JQLX01000013_gene1447	2.56e-89	279.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2M6KR@213113|Desulfurellales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_163607_1	1126627.BAWE01000004_gene4279	7.71e-101	333.0	2DUMH@1|root,33R9V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33989_2	1408418.JNJH01000098_gene301	1.24e-82	256.0	COG3267@1|root,COG3267@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02450,ko:K03112	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
k59_4835_1	290512.Paes_0550	2.04e-38	141.0	COG0205@1|root,COG0205@2|Bacteria,1FEH2@1090|Chlorobi	1090|Chlorobi	G	PFAM phosphofructokinase	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_16823_1	187303.BN69_3232	2.06e-23	103.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_128178_1	1169144.KB910924_gene435	7.46e-34	126.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus	91061|Bacilli	S	stress-induced protein	yloC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_128178_2	1499967.BAYZ01000019_gene6317	6.39e-31	117.0	COG0194@1|root,COG0194@2|Bacteria,2NPIN@2323|unclassified Bacteria	2|Bacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8,4.1.1.23	ko:K00942,ko:K01591	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00050,M00051	R00332,R00965,R02090	RC00002,RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Guanylate_kin
k59_57647_1	7029.ACYPI33010-PA	5.75e-62	231.0	28PQ2@1|root,2QWCA@2759|Eukaryota,3AGTM@33154|Opisthokonta,3BYZ0@33208|Metazoa,3DEZA@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_175660_2	526224.Bmur_2263	1.8e-69	245.0	COG5283@1|root,COG5283@2|Bacteria,2JAQ2@203691|Spirochaetes	203691|Spirochaetes	S	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_140584_1	134676.ACPL_1213	7.53e-36	139.0	COG0714@1|root,COG0714@2|Bacteria,2GNQ8@201174|Actinobacteria,4DBWK@85008|Micromonosporales	201174|Actinobacteria	S	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
k59_40948_1	1122201.AUAZ01000025_gene3560	1.69e-67	221.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,4655F@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_40732_1	1391646.AVSU01000016_gene3161	3.87e-68	218.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia,25UHS@186804|Peptostreptococcaceae	186801|Clostridia	GM	Male sterility protein	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_11307_1	204669.Acid345_0636	2.09e-91	279.0	COG0520@1|root,COG0520@2|Bacteria,3Y2SC@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_152567_1	7897.ENSLACP00000003383	2.51e-92	295.0	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa,3D0QV@33213|Bilateria,48CBX@7711|Chordata,49FC8@7742|Vertebrata	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_22727_1	7897.ENSLACP00000007020	5.58e-126	382.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,487I3@7711|Chordata,4962T@7742|Vertebrata	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.3.1.15	ko:K13506	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Exo_endo_phos_2,RVT_1
k59_40756_2	1286632.P278_08590	8.15e-50	164.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1I1AR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_51724_1	1120985.AUMI01000019_gene2299	1.13e-59	196.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4H2A2@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_51724_2	33035.JPJF01000077_gene70	2.3e-31	123.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3XYGR@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_11327_1	663278.Ethha_0102	2.01e-41	160.0	COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WJR8@541000|Ruminococcaceae	186801|Clostridia	D	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_11327_4	264732.Moth_0242	2.21e-05	52.0	COG5492@1|root,COG5492@2|Bacteria,1VX4D@1239|Firmicutes,252B8@186801|Clostridia	186801|Clostridia	N	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,TIG
k59_129094_1	1191523.MROS_2287	3e-67	218.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
k59_58483_1	6412.HelroP172618	5.97e-14	80.5	2DZJ4@1|root,2S72P@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111233_1	6669.EFX67499	4.2e-27	114.0	2AENI@1|root,2RYW1@2759|Eukaryota,39ZI9@33154|Opisthokonta,3BQBS@33208|Metazoa,3D2GS@33213|Bilateria,41TJ8@6656|Arthropoda	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34883_1	1321782.HMPREF1986_01890	4.04e-50	174.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2PR4W@265975|Oribacterium	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_93536_1	266264.Rmet_1145	6.8e-24	108.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,1KGJ6@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	torA	-	1.7.2.3	ko:K07811,ko:K07812,ko:K08351	ko00780,ko01100,ko02020,map00780,map01100,map02020	-	R10127	RC03056	ko00000,ko00001,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding
k59_29198_1	83406.HDN1F_23550	4.43e-66	207.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1J4EN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_22774_1	945713.IALB_0266	3.73e-87	270.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
k59_11343_1	481448.Minf_0431	8.4e-26	97.8	COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia,37GVN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_11343_2	207559.Dde_2429	2.17e-25	101.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2M8AS@213115|Desulfovibrionales	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG-2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_46575_1	6412.HelroP169060	1.82e-36	132.0	2E3R9@1|root,2SARV@2759|Eukaryota,3AEAR@33154|Opisthokonta,3BW16@33208|Metazoa	33208|Metazoa	S	hAT family C-terminal dimerisation region	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_129118_2	768706.Desor_1122	1.6e-07	57.4	COG0591@1|root,COG0591@2|Bacteria,1TQEZ@1239|Firmicutes,24AJN@186801|Clostridia,262IJ@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_22776_1	401053.AciPR4_4148	5.23e-34	132.0	COG3613@1|root,COG3613@2|Bacteria	2|Bacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4406
k59_58497_1	4558.Sb04g027355.1	3.88e-13	75.1	2C7QK@1|root,2QUNQ@2759|Eukaryota,37QB2@33090|Viridiplantae	33090|Viridiplantae	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT
k59_51758_1	626939.HMPREF9443_00729	1.16e-07	56.2	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4H3JJ@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_51758_2	517418.Ctha_1424	1.96e-06	51.6	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1FDSH@1090|Chlorobi	1090|Chlorobi	M	PFAM surface antigen (D15)	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
k59_129124_2	1379698.RBG1_1C00001G1198	2.26e-27	100.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	fdxN	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Fer4,HTH_3,HTH_31
k59_82124_1	1191523.MROS_0484	2.73e-96	305.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_75942_1	102107.XP_008227691.1	1.02e-18	79.3	2DGHD@1|root,2S5UJ@2759|Eukaryota,37W10@33090|Viridiplantae,3GK6F@35493|Streptophyta,4JUJY@91835|fabids	35493|Streptophyta	J	Ribosomal protein S10p/S20e	RPS10	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_40811_1	1386969.AWTB01000059_gene2362	3.39e-11	67.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4GBXP@85026|Gordoniaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve
k59_82130_1	376686.Fjoh_1588	6.36e-15	79.3	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,1IJ7E@117743|Flavobacteriia,2NTIP@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_116433_1	1379698.RBG1_1C00001G0406	1.44e-32	124.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
k59_82134_1	1267534.KB906757_gene873	2.08e-33	124.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria,2JI58@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_105040_1	1521187.JPIM01000063_gene2494	4.03e-14	77.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi,375V8@32061|Chloroflexia	32061|Chloroflexia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
k59_11369_1	8479.XP_005305226.1	1.28e-67	224.0	28HC0@1|root,2QPQD@2759|Eukaryota,39S4C@33154|Opisthokonta,3BMKF@33208|Metazoa,3D63M@33213|Bilateria,48BPK@7711|Chordata,495JJ@7742|Vertebrata,4CMFM@8459|Testudines	33208|Metazoa	S	ZnF_TTF	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_40834_1	1123256.KB907930_gene3537	1.74e-06	52.4	COG0845@1|root,COG0845@2|Bacteria,1QE86@1224|Proteobacteria,1S0IT@1236|Gammaproteobacteria,1X3RG@135614|Xanthomonadales	135614|Xanthomonadales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_29229_1	1232437.KL662007_gene1684	1.36e-123	364.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42SSD@68525|delta/epsilon subdivisions,2WPWR@28221|Deltaproteobacteria,2MK6M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_187512_1	445971.ANASTE_02056	1.86e-30	110.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,25W3Z@186806|Eubacteriaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_187512_2	546269.HMPREF0389_00839	1.48e-09	56.2	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,25RVP@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_187512_3	1191523.MROS_0207	3.86e-08	51.2	COG0186@1|root,COG0186@2|Bacteria	2|Bacteria	J	rRNA binding	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_876_1	31234.CRE11381	4.15e-42	157.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_89000_1	1122918.KB907288_gene949	2.3e-28	114.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,26V03@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase dimerisation domain	-	-	-	ko:K12940	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_53796_1	1121878.AUGL01000017_gene1811	2.95e-57	201.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_159382_2	118166.JH976537_gene1678	7.28e-133	397.0	COG0175@1|root,COG0175@2|Bacteria,1GCMX@1117|Cyanobacteria,1HF9G@1150|Oscillatoriales	1117|Cyanobacteria	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
k59_40285_1	31234.CRE23042	5.07e-27	108.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_146090_2	1356852.N008_02395	1.06e-19	92.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47KRU@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_134148_2	9778.XP_004387141.1	1.99e-279	810.0	COG2801@1|root,KOG1721@1|root,KOG0017@2759|Eukaryota,KOG1721@2759|Eukaryota,39P19@33154|Opisthokonta,3CQJS@33208|Metazoa,3E6SR@33213|Bilateria,48SDS@7711|Chordata,49NWV@7742|Vertebrata,3JD1A@40674|Mammalia,355I3@311790|Afrotheria	33208|Metazoa	L	leucine rich region	ZBED9	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,SCAN
k59_57935_1	1121406.JAEX01000003_gene1772	1.08e-31	120.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,2MA4Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
k59_10903_1	1122605.KB893646_gene8	1.37e-15	75.9	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,1ITCU@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_75484_1	329726.AM1_5157	1.26e-41	159.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CbiA,NB-ARC,TIR_2,TPR_10,TPR_12
k59_17172_1	584708.Apau_0524	2.28e-24	105.0	COG1171@1|root,COG1171@2|Bacteria,3TAF2@508458|Synergistetes	508458|Synergistetes	E	Diaminopropionate ammonia-lyase	-	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
k59_134160_1	866546.EPY52228	8.64e-31	127.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3NVKU@4751|Fungi,3QP1S@4890|Ascomycota,3MDV8@451866|Taphrinomycotina	4751|Fungi	L	Retrotransposable element transposon Tf2-type	-	GO:0000943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003887,GO:0003964,GO:0004518,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006278,GO:0006508,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019538,GO:0032196,GO:0032197,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140096,GO:0140097,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Chromo,RVP_2,RVT_1,rve
k59_186921_1	744985.HIMB59_00005380	9.54e-23	94.4	COG0395@1|root,COG0395@2|Bacteria,1MXEM@1224|Proteobacteria,2TUQV@28211|Alphaproteobacteria,4BS0Y@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM Binding-protein-dependent transport system inner membrane component	ycjP	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_186921_2	1366046.HIMB11_03198	3.45e-77	238.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TQZY@28211|Alphaproteobacteria,3ZG1C@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	P	COG1175 ABC-type sugar transport systems, permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_157385_1	237368.SCABRO_01880	3.36e-79	244.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_115897_1	933262.AXAM01000008_gene1927	3.1e-74	249.0	28HYC@1|root,2Z83T@2|Bacteria,1QEBM@1224|Proteobacteria,42NM2@68525|delta/epsilon subdivisions,2WM1N@28221|Deltaproteobacteria,2MIIE@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115902_1	1232437.KL662061_gene4187	1.06e-30	123.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_169784_1	1078020.KEK_03452	2.91e-15	74.3	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,238N2@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_169784_2	1449357.JQLK01000001_gene2110	3.84e-06	51.6	COG0836@1|root,COG0836@2|Bacteria,1WIIC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_181433_1	698440.XP_007296712.1	2.82e-51	176.0	COG0160@1|root,KOG1404@2759|Eukaryota,38EI2@33154|Opisthokonta,3NUMN@4751|Fungi,3QMAS@4890|Ascomycota,20ZVD@147548|Leotiomycetes	4751|Fungi	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_152027_1	562970.Btus_2762	1.24e-58	197.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,279NT@186823|Alicyclobacillaceae	91061|Bacilli	E	Peptidase dimerisation domain	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_104536_1	575540.Isop_3695	2.97e-35	135.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
k59_104536_2	243090.RB1248	6.84e-65	207.0	COG1131@1|root,COG1131@2|Bacteria,2IXQV@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_128567_1	1094980.Mpsy_2981	5.86e-37	150.0	COG3413@1|root,arCOG02338@1|root,arCOG02346@1|root,arCOG02348@1|root,arCOG02350@1|root,arCOG02360@1|root,arCOG02376@1|root,arCOG02278@2157|Archaea,arCOG02338@2157|Archaea,arCOG02346@2157|Archaea,arCOG02348@2157|Archaea,arCOG02350@2157|Archaea,arCOG02360@2157|Archaea,arCOG02376@2157|Archaea,2Y7T0@28890|Euryarchaeota,2NBM5@224756|Methanomicrobia	224756|Methanomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS
k59_75497_2	3880.AES58514	2.98e-77	241.0	COG0048@1|root,COG0838@1|root,KOG1750@2759|Eukaryota,KOG4662@2759|Eukaryota,37UKS@33090|Viridiplantae,3GIMC@35493|Streptophyta,4JU73@91835|fabids	35493|Streptophyta	J	Ribosomal protein S12/S23	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_75497_3	29760.VIT_00s0873g00010.t01	4.72e-79	235.0	COG0048@1|root,KOG1750@2759|Eukaryota,37UKS@33090|Viridiplantae,3GIMC@35493|Streptophyta	35493|Streptophyta	J	Rps12 protein	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_75497_4	4081.Solyc00g020040.1.1	2.84e-121	348.0	2C63N@1|root,2QT9Q@2759|Eukaryota,37P22@33090|Viridiplantae,3GH9T@35493|Streptophyta	35493|Streptophyta	-	-	ccmB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	-	-	-	-	-	-	-	-	-	-
k59_169790_1	926561.KB900623_gene1012	3.32e-62	209.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WAAC@53433|Halanaerobiales	186801|Clostridia	O	chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_122624_1	72004.XP_005895158.1	3.4e-13	74.7	COG0450@1|root,KOG0852@2759|Eukaryota,38B9P@33154|Opisthokonta,3B9IG@33208|Metazoa,3CS1I@33213|Bilateria,484GH@7711|Chordata,48VF7@7742|Vertebrata,3J2V1@40674|Mammalia,4IVS2@91561|Cetartiodactyla	33208|Metazoa	O	Thioredoxin-dependent peroxide reductase	PRDX3	GO:0000003,GO:0000302,GO:0001890,GO:0001893,GO:0002237,GO:0002376,GO:0002520,GO:0003006,GO:0003674,GO:0003824,GO:0004601,GO:0004857,GO:0004866,GO:0004869,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005768,GO:0005769,GO:0005829,GO:0006355,GO:0006464,GO:0006807,GO:0006915,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0007275,GO:0007565,GO:0008022,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008379,GO:0008785,GO:0009056,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009889,GO:0009892,GO:0009987,GO:0010033,GO:0010035,GO:0010466,GO:0010468,GO:0010556,GO:0010563,GO:0010605,GO:0010941,GO:0010951,GO:0012501,GO:0012505,GO:0016043,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0018158,GO:0018171,GO:0018193,GO:0018198,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022414,GO:0030097,GO:0030099,GO:0030154,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0031326,GO:0031410,GO:0031974,GO:0031982,GO:0032268,GO:0032269,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033554,GO:0033673,GO:0033993,GO:0034599,GO:0034614,GO:0036211,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042391,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0042981,GO:0043027,GO:0043028,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043170,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043281,GO:0043412,GO:0043523,GO:0043524,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045861,GO:0045936,GO:0046677,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051187,GO:0051246,GO:0051248,GO:0051252,GO:0051336,GO:0051338,GO:0051346,GO:0051348,GO:0051704,GO:0051707,GO:0051716,GO:0051881,GO:0051920,GO:0052547,GO:0052548,GO:0055114,GO:0060135,GO:0060255,GO:0060548,GO:0061134,GO:0061135,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070887,GO:0071704,GO:0071840,GO:0072593,GO:0080090,GO:0097237,GO:0097708,GO:0098754,GO:0098772,GO:0098869,GO:1901214,GO:1901215,GO:1901564,GO:1901700,GO:1901701,GO:1903506,GO:1990748,GO:2000112,GO:2000116,GO:2000117,GO:2001141	1.11.1.15	ko:K13279,ko:K20011	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_146135_3	1405.DJ92_5252	6.15e-06	46.2	2C0WQ@1|root,307CH@2|Bacteria,1U1FD@1239|Firmicutes,4INVI@91061|Bacilli,1ZP09@1386|Bacillus	91061|Bacilli	S	Phage protein (N4 Gp49/phage Sf6 gene 66) family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_gp49_66
k59_28734_2	1122963.AUHB01000005_gene2668	1.3e-36	130.0	COG4319@1|root,COG4319@2|Bacteria,1N8K3@1224|Proteobacteria,2UXUT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_28734_3	1121930.AQXG01000002_gene2050	1.63e-70	230.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_128604_1	243231.GSU0475	3.84e-24	107.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,MASE3,PAS_3,PAS_4,PAS_9,dCache_1
k59_99559_1	1051613.XP_003009648.1	2.9e-07	52.4	COG0604@1|root,KOG1198@2759|Eukaryota,3A0AV@33154|Opisthokonta,3P1SE@4751|Fungi,3QT55@4890|Ascomycota,2198U@147550|Sordariomycetes,1F3S6@1028384|Glomerellales	4751|Fungi	C	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_93074_1	1500890.JQNL01000001_gene468	0.000324	50.1	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,1X4D8@135614|Xanthomonadales	135614|Xanthomonadales	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_139956_1	1379698.RBG1_1C00001G0378	5.96e-83	256.0	COG0150@1|root,COG0150@2|Bacteria,2NNUJ@2323|unclassified Bacteria	2|Bacteria	F	AIR synthase related protein, N-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1,6.3.4.13	ko:K01933,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844,iECSF_1327.ECSF_2340	AIRS,AIRS_C
k59_186970_1	497964.CfE428DRAFT_2340	4.28e-87	285.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_51307_1	391616.OA238_c43630	4.69e-36	130.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_28740_1	694431.DESACE_02765	5.36e-61	193.0	arCOG10401@1|root,2ZA7Y@2|Bacteria,1R45R@1224|Proteobacteria,42MDG@68525|delta/epsilon subdivisions,2WKTC@28221|Deltaproteobacteria,2M7KR@213113|Desulfurellales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146146_1	340099.Teth39_2137	1.86e-57	200.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42EPT@68295|Thermoanaerobacterales	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_40353_1	1379698.RBG1_1C00001G0334	3.09e-103	316.0	COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_0688	Urocanase,Urocanase_C,Urocanase_N
k59_186982_1	118005.AWNK01000013_gene890	4.58e-23	99.8	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_81628_1	1304880.JAGB01000001_gene560	3.6e-121	377.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 38 C-terminal domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
k59_116696_1	338963.Pcar_1355	2.04e-54	191.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,43STW@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp34H-6	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,dCache_1,dCache_3,sCache_2
k59_52059_4	395493.BegalDRAFT_3327	8.54e-16	81.3	COG2010@1|root,COG2010@2|Bacteria,1QYUH@1224|Proteobacteria,1T3V8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_46338_1	321332.CYB_2673	1.82e-62	207.0	COG0056@1|root,COG0056@2|Bacteria,1FZXK@1117|Cyanobacteria,1GYZE@1129|Synechococcus	1117|Cyanobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_58260_1	96561.Dole_0733	6.44e-21	90.9	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2MI89@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_58260_2	1380356.JNIK01000018_gene627	4.38e-26	104.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4ESN1@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_22559_1	1499967.BAYZ01000131_gene345	7.04e-15	75.9	COG0840@1|root,COG0840@2|Bacteria,2NQS9@2323|unclassified Bacteria	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k59_22559_2	1499967.BAYZ01000131_gene344	4.36e-10	62.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_111018_1	936574.HMPREF1508_0468	2.2e-43	160.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia	186801|Clostridia	L	DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_5424_2	1038858.AXBA01000002_gene3789	5.99e-09	58.2	2CCFB@1|root,32RVJ@2|Bacteria,1NJKM@1224|Proteobacteria,2UW9X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	zinc-finger-containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3268
k59_22562_1	446468.Ndas_1185	2.14e-14	70.5	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria	201174|Actinobacteria	E	Chorismate mutase	-	-	-	-	-	-	-	-	-	-	-	-	CM_1
k59_51571_1	1123008.KB905695_gene2488	1.28e-47	172.0	COG1629@1|root,COG4771@2|Bacteria,4NIUN@976|Bacteroidetes,2FPXH@200643|Bacteroidia,22ZFN@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_164258_1	644966.Tmar_0920	2e-47	170.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WCVB@538999|Clostridiales incertae sedis	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_99787_1	7029.ACYPI53881-PA	9.08e-42	167.0	KOG4441@1|root,KOG4441@2759|Eukaryota	2759|Eukaryota	KLT	protein ubiquitination	-	-	-	ko:K10443,ko:K10444,ko:K10455,ko:K10457,ko:K10465,ko:K21912	-	-	-	-	ko00000,ko04121	-	-	-	BACK,BTB,Dimer_Tnp_hAT,Kelch_1
k59_58280_1	1242864.D187_007363	6.17e-36	139.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140179_3	7918.ENSLOCP00000022353	9.01e-25	109.0	COG2801@1|root,KOG0017@2759|Eukaryota,3A0H6@33154|Opisthokonta,3BQ6X@33208|Metazoa,3D72R@33213|Bilateria,48EEU@7711|Chordata,49BCE@7742|Vertebrata,4A6CM@7898|Actinopterygii	33208|Metazoa	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_157619_1	91604.ID47_10820	4.7e-08	58.9	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,47FBZ@766|Rickettsiales	766|Rickettsiales	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_11178_1	1120934.KB894432_gene6182	7.15e-05	47.0	COG1345@1|root,COG1345@2|Bacteria,2IBVB@201174|Actinobacteria,4EAIC@85010|Pseudonocardiales	201174|Actinobacteria	N	Flagellar hook-associated protein 2 N-terminus	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_11178_2	1210884.HG799473_gene15053	2.55e-15	82.4	COG1344@1|root,COG1344@2|Bacteria,2IX6G@203682|Planctomycetes	203682|Planctomycetes	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_152372_1	27923.ML006315a-PA	9.18e-09	62.8	COG0171@1|root,KOG1075@1|root,KOG1075@2759|Eukaryota,KOG2303@2759|Eukaryota	2759|Eukaryota	H	NAD+ synthase (glutamine-hydrolyzing) activity	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_70195_1	1378168.N510_00492	3.48e-101	325.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes	1239|Firmicutes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_51591_2	1173020.Cha6605_1455	3.49e-15	76.3	COG1028@1|root,COG1028@2|Bacteria,1G0IE@1117|Cyanobacteria	1117|Cyanobacteria	IQ	PFAM short chain dehydrogenase	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_5448_1	876044.IMCC3088_2379	6.71e-13	70.1	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
k59_29017_1	292459.STH2589	6.14e-20	94.7	COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,24DMW@186801|Clostridia	186801|Clostridia	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
k59_93343_1	1379698.RBG1_1C00001G0660	5.76e-29	124.0	COG2067@1|root,COG2067@2|Bacteria,2NPN1@2323|unclassified Bacteria	2|Bacteria	I	Membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_17567_1	883.DvMF_1194	6.08e-06	50.8	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,2MB0F@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_17567_2	500635.MITSMUL_04720	3.74e-29	119.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4H260@909932|Negativicutes	909932|Negativicutes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_11180_1	644282.Deba_1222	1.69e-40	141.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_11180_2	404380.Gbem_1213	1.52e-13	70.5	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
k59_116223_4	883103.HMPREF9703_01468	9.86e-13	70.9	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,27FKF@186828|Carnobacteriaceae	91061|Bacilli	E	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_116223_12	376733.IT41_18355	1.27e-16	85.1	COG4227@1|root,COG4227@2|Bacteria	2|Bacteria	L	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3560
k59_40611_1	10224.XP_006818607.1	5.54e-68	223.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa	33208|Metazoa	L	steroid hormone mediated signaling pathway	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_75760_2	517722.AEUE01000002_gene2021	2.92e-15	75.1	COG1670@1|root,COG1670@2|Bacteria,1N9TX@1224|Proteobacteria,2USFR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_140198_1	585394.RHOM_15685	1.69e-32	124.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_87677_1	517418.Ctha_0315	1.25e-62	203.0	COG2876@1|root,COG2876@2|Bacteria,1FEJR@1090|Chlorobi	1090|Chlorobi	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_17576_1	219305.MCAG_00006	1.03e-24	102.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4DEDK@85008|Micromonosporales	201174|Actinobacteria	K	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_5458_1	96561.Dole_1704	1.81e-24	110.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5463_1	929556.Solca_1359	1.33e-35	139.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1IPA6@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
k59_29026_1	121225.PHUM233500-PA	2.42e-10	62.0	COG1448@1|root,KOG1412@2759|Eukaryota,39W2P@33154|Opisthokonta,3BE99@33208|Metazoa,3CZIY@33213|Bilateria,41V8T@6656|Arthropoda,3SJV5@50557|Insecta,3E7PF@33342|Paraneoptera	33208|Metazoa	E	Aminotransferase class I and II	GOT1	GO:0000323,GO:0003254,GO:0003674,GO:0003824,GO:0004069,GO:0004609,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005764,GO:0005773,GO:0005777,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006082,GO:0006094,GO:0006103,GO:0006106,GO:0006107,GO:0006114,GO:0006520,GO:0006531,GO:0006532,GO:0006533,GO:0006536,GO:0006537,GO:0006538,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009068,GO:0009084,GO:0009605,GO:0009612,GO:0009628,GO:0009719,GO:0009725,GO:0009743,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010646,GO:0010647,GO:0010712,GO:0010713,GO:0014070,GO:0016051,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016831,GO:0017015,GO:0019222,GO:0019318,GO:0019319,GO:0019400,GO:0019401,GO:0019550,GO:0019551,GO:0019725,GO:0019751,GO:0019752,GO:0023051,GO:0023052,GO:0023056,GO:0030003,GO:0030154,GO:0030424,GO:0030511,GO:0031406,GO:0031960,GO:0031974,GO:0031981,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032965,GO:0032966,GO:0033267,GO:0033993,GO:0034637,GO:0035902,GO:0036094,GO:0042221,GO:0042391,GO:0042579,GO:0042592,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043648,GO:0043649,GO:0043650,GO:0043679,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044281,GO:0044282,GO:0044283,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046165,GO:0046173,GO:0046364,GO:0046394,GO:0046395,GO:0046686,GO:0047801,GO:0048518,GO:0048519,GO:0048522,GO:0048545,GO:0048583,GO:0048584,GO:0048869,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051186,GO:0051384,GO:0051480,GO:0051481,GO:0051716,GO:0051881,GO:0051900,GO:0051902,GO:0055065,GO:0055074,GO:0055080,GO:0055081,GO:0055082,GO:0055088,GO:0055089,GO:0060290,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071214,GO:0071260,GO:0071310,GO:0071375,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0072503,GO:0072507,GO:0090092,GO:0090100,GO:0090287,GO:0097458,GO:0098771,GO:0098793,GO:0104004,GO:0120025,GO:0120038,GO:0150034,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901615,GO:1901617,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903844,GO:1903846,GO:1904180,GO:1990267	2.6.1.1	ko:K14454	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00710,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00710,map00950,map00960,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00170,M00171	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007,ko04131,ko04147	-	-	-	Aminotran_1_2
k59_104851_1	941449.dsx2_0537	7.87e-63	209.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2M8HN@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_105655_2	313606.M23134_01325	8.61e-16	80.1	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,47JHF@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
k59_23438_1	537013.CLOSTMETH_02048	3.96e-10	65.9	COG1538@1|root,COG3250@1|root,COG1538@2|Bacteria,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,FIVAR,Glyco_hydro_106,Glyco_hydro_2_N,OEP
k59_116962_1	1122212.AULO01000011_gene548	7.73e-08	54.3	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,1RZKS@1236|Gammaproteobacteria,1XJS2@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_23460_1	261292.Nit79A3_2343	1.86e-09	63.2	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
k59_116991_1	1453505.JASY01000012_gene4222	1.97e-40	152.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia,2NUYY@237|Flavobacterium	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,MAM,PepSY,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,fn3
k59_23481_1	1379698.RBG1_1C00001G1150	1.56e-36	137.0	COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.proS,iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_115407_2	1191523.MROS_0573	1.46e-31	115.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_10,TetR_N
k59_145602_3	1125863.JAFN01000001_gene1438	3.44e-58	204.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
k59_74956_1	7918.ENSLOCP00000022184	4.99e-24	101.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3B9WN@33208|Metazoa,3D1S8@33213|Bilateria,48C1W@7711|Chordata,49N8J@7742|Vertebrata,4A94B@7898|Actinopterygii	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_10388_2	1121012.AUKX01000064_gene1065	1.68e-49	173.0	COG5421@1|root,COG5421@2|Bacteria,4PAGJ@976|Bacteroidetes,1IAIH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_146276_1	1265505.ATUG01000002_gene1370	2.48e-80	271.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M2K@68525|delta/epsilon subdivisions,2WK48@28221|Deltaproteobacteria,2MJ6X@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_104677_1	555779.Dthio_PD2454	2.34e-119	360.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2M88N@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_81765_1	1042326.AZNV01000040_gene553	6.12e-15	75.9	2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,2UDJQ@28211|Alphaproteobacteria,4BEE4@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2938
k59_157536_1	999419.HMPREF1077_00744	4.4e-41	139.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia,22XW8@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_157536_2	314271.RB2654_01170	2.74e-06	49.3	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k59_110917_1	702113.PP1Y_Mpl4496	1.36e-09	65.9	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,1R5EH@1224|Proteobacteria,2U45J@28211|Alphaproteobacteria,2KEKX@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_81767_1	1379698.RBG1_1C00001G0287	3.29e-61	209.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_134378_1	1121104.AQXH01000005_gene180	5.58e-08	54.7	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes,1IZ6F@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
k59_5324_1	1162668.LFE_0875	3.59e-74	250.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_11084_1	517418.Ctha_0820	1.54e-80	249.0	COG4152@1|root,COG4152@2|Bacteria,1FETW@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_93244_1	640081.Dsui_3412	4.18e-10	67.0	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,2VPPP@28216|Betaproteobacteria,2KVX9@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_93244_2	1265505.ATUG01000002_gene1393	1.56e-18	81.6	COG1871@1|root,COG1871@2|Bacteria,1RAWA@1224|Proteobacteria,42QP1@68525|delta/epsilon subdivisions,2WQBY@28221|Deltaproteobacteria,2MJPU@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD1	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_140088_1	511051.CSE_12560	2.85e-13	70.1	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
k59_187131_1	945713.IALB_0304	1.25e-264	760.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
k59_5330_2	1192034.CAP_1864	6.95e-38	130.0	COG3436@1|root,COG3436@2|Bacteria	2|Bacteria	L	PFAM IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_58184_1	457424.BFAG_04347	2.64e-11	72.4	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,2FN2J@200643|Bacteroidia,4AK82@815|Bacteroidaceae	976|Bacteroidetes	MU	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_175181_1	449447.MAE_58430	1.45e-14	76.6	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G3YK@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
k59_58190_1	861299.J421_2298	1.63e-56	191.0	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_58190_2	113355.CM001775_gene28	1.99e-28	113.0	COG0286@1|root,COG0286@2|Bacteria,1G2AI@1117|Cyanobacteria	1117|Cyanobacteria	V	Type I restriction-modification system methyltransferase subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_157549_1	1191523.MROS_2234	8.89e-74	240.0	COG1115@1|root,COG1115@2|Bacteria	2|Bacteria	E	amino acid carrier protein	dagA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_134408_1	400682.PAC_15724810	2.97e-14	82.8	KOG1075@1|root,KOG1075@2759|Eukaryota,3AK7D@33154|Opisthokonta,3BPZQ@33208|Metazoa	33208|Metazoa	T	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2,Exo_endo_phos_2,RVT_1
k59_46283_1	6412.HelroP179125	4.45e-20	95.1	KOG1075@1|root,KOG1075@2759|Eukaryota,3AQ2W@33154|Opisthokonta,3BUFE@33208|Metazoa	33208|Metazoa	S	Endonuclease-reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2
k59_28900_1	1267535.KB906767_gene1616	7.92e-07	50.8	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria	57723|Acidobacteria	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_28900_2	1283284.AZUK01000001_gene178	1.74e-35	129.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1Y3WB@135624|Aeromonadales	135624|Aeromonadales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_169961_2	573413.Spirs_2497	3.99e-14	73.9	COG3740@1|root,COG3740@2|Bacteria,2JAN9@203691|Spirochaetes	203691|Spirochaetes	S	PFAM peptidase U35 phage prohead HK97	-	-	-	ko:K06904	-	-	-	-	ko00000	-	-	-	Peptidase_S78
k59_146337_1	314724.BT0337	1.31e-90	280.0	COG0148@1|root,COG0148@2|Bacteria,2J59Y@203691|Spirochaetes	203691|Spirochaetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_116109_1	13735.ENSPSIP00000000389	5.19e-21	96.3	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta	33154|Opisthokonta	IQ	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_34609_1	7029.ACYPI40330-PA	4.23e-22	102.0	2E1I0@1|root,2S8UZ@2759|Eukaryota,3A9DK@33154|Opisthokonta,3BV6P@33208|Metazoa,3DIJ1@33213|Bilateria,423YJ@6656|Arthropoda,3T021@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_116117_1	1142394.PSMK_18670	8.34e-34	130.0	COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_116117_2	44056.XP_009038798.1	4.69e-09	57.8	COG1947@1|root,2QT9C@2759|Eukaryota	2759|Eukaryota	I	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	CMK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009507,GO:0009509,GO:0009536,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_181612_1	483219.LILAB_29905	4.62e-40	139.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2WQG9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_75666_1	4572.TRIUR3_06919-P1	7.08e-51	162.0	COG1007@1|root,KOG4668@2759|Eukaryota,38006@33090|Viridiplantae,3GPQB@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_75666_2	29730.Gorai.001G164700.1	4.8e-45	151.0	2B8KU@1|root,2S0S2@2759|Eukaryota,37UKM@33090|Viridiplantae,3GJ2Y@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75666_3	3880.AES93933	9.78e-30	120.0	COG5272@1|root,KOG2381@1|root,KOG0001@2759|Eukaryota,KOG2381@2759|Eukaryota,37RMX@33090|Viridiplantae,3G9F1@35493|Streptophyta,4JGUX@91835|fabids	35493|Streptophyta	OT	Phosphatidylinositol 4-kinase gamma 2-like	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0009651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase,ubiquitin
k59_146349_1	981369.JQMJ01000003_gene7894	1.06e-23	98.6	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,2NEBJ@228398|Streptacidiphilus	201174|Actinobacteria	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_169979_1	1410630.JNKP01000001_gene2298	1.58e-36	142.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,27TDQ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
k59_169979_2	1094508.Tsac_0539	0.000969	42.4	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,42F7T@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase class V	csd2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_93268_1	866536.Belba_2607	1.85e-22	100.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,47JXU@768503|Cytophagia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140153_1	7425.NV14023-PA	2.43e-68	220.0	COG2124@1|root,COG5262@1|root,KOG0157@2759|Eukaryota,KOG1756@2759|Eukaryota,3A1K0@33154|Opisthokonta,3BPSK@33208|Metazoa,3D6YF@33213|Bilateria	33208|Metazoa	B	Protein heterodimerization activity	-	-	-	ko:K11251,ko:K15001	ko04217,ko05034,ko05322,map04217,map05034,map05322	-	-	-	ko00000,ko00001,ko00199,ko01000,ko03036,ko04147	-	-	-	Histone,Histone_H2A_C
k59_140153_2	10029.XP_007634688.1	8.66e-77	250.0	COG2036@1|root,COG5262@1|root,KOG1745@2759|Eukaryota,KOG1756@2759|Eukaryota,39ZTV@33154|Opisthokonta,3BPDH@33208|Metazoa,3D6BK@33213|Bilateria,48E1W@7711|Chordata,49B7M@7742|Vertebrata,3JGKY@40674|Mammalia,35PSM@314146|Euarchontoglires,4Q54X@9989|Rodentia	33208|Metazoa	B	Core histone H2A/H2B/H3/H4	HIST3H3	GO:0000228,GO:0000723,GO:0000726,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016233,GO:0022607,GO:0031333,GO:0031490,GO:0031491,GO:0031492,GO:0031497,GO:0031974,GO:0031981,GO:0032200,GO:0032459,GO:0032460,GO:0032991,GO:0032993,GO:0033554,GO:0034622,GO:0034641,GO:0034728,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0044877,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051259,GO:0051262,GO:0051276,GO:0051290,GO:0051291,GO:0051716,GO:0060249,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K11253,ko:K11275	ko05034,ko05202,ko05322,map05034,map05202,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone
k59_181641_1	386415.NT01CX_1532	1.78e-17	86.7	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,36JCC@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_87602_1	1121101.HMPREF1532_04085	6.6e-45	164.0	COG0383@1|root,COG1404@1|root,COG0383@2|Bacteria,COG1404@2|Bacteria,4NJ12@976|Bacteroidetes,2FNHX@200643|Bacteroidia,4AMY9@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 38 C-terminal domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,F5_F8_type_C,Glyco_hydro_38,Glyco_hydro_38C
k59_11144_1	997346.HMPREF9374_2383	4.58e-42	143.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,4HACH@91061|Bacilli,27B6Q@186824|Thermoactinomycetaceae	91061|Bacilli	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_11144_2	383372.Rcas_1322	2.39e-06	50.4	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi,375IZ@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_169990_1	3847.GLYMA13G11980.1	1.46e-81	274.0	2CUMQ@1|root,2RN4M@2759|Eukaryota,37U2D@33090|Viridiplantae,3GX5D@35493|Streptophyta,4JTXP@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_99752_1	458817.Shal_1190	4.32e-22	101.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,2QEPQ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_29,rve
k59_35975_1	1185652.USDA257_c12210	4.1e-12	69.7	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,4BCIB@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC-type sugar transport systems, ATPase components	-	-	-	ko:K10191	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	ABC_tran,TOBE_2
k59_100515_1	931626.Awo_c22100	5e-51	175.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,25UWA@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_165283_1	1379698.RBG1_1C00001G1612	1.08e-157	451.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484	-	ko:K02358,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_165283_2	309799.DICTH_0834	6.3e-05	45.1	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_41892_1	1265310.CCBD010000047_gene2554	2.72e-12	66.2	COG2020@1|root,COG2020@2|Bacteria,2IIDW@201174|Actinobacteria,238RM@1762|Mycobacteriaceae	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_41892_2	1282362.AEAC466_03765	2.95e-14	74.3	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,2VEWB@28211|Alphaproteobacteria,2KIII@204458|Caulobacterales	204458|Caulobacterales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_714_1	7029.ACYPI27956-PA	3.77e-22	101.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,42BZI@6656|Arthropoda,3SVZS@50557|Insecta,3EDZB@33342|Paraneoptera	33208|Metazoa	-	-	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_129853_1	1379698.RBG1_1C00001G1750	2.38e-16	83.6	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
k59_30067_1	10228.TriadP29177	1.46e-106	347.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa	33208|Metazoa	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	CAD	GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700	2.1.3.2,3.5.2.3,6.3.5.5	ko:K11540	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Amidohydro_1,CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS,OTCace,OTCace_N
k59_159231_1	1380355.JNIJ01000014_gene484	8.7e-19	84.3	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,3JTFI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k59_159231_2	1382306.JNIM01000001_gene1167	3.34e-11	63.5	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2683	PfkB
k59_147423_1	1353276.JADR01000008_gene832	2.38e-55	185.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia	976|Bacteroidetes	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_124109_1	550540.Fbal_0978	1.3e-12	73.2	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_94613_1	1304883.KI912532_gene2348	2.35e-51	182.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KW8G@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
k59_6578_1	218851.Aquca_044_00093.1	0.0	1053.0	28JG1@1|root,2QRV6@2759|Eukaryota,37HEX@33090|Viridiplantae,3GE8P@35493|Streptophyta	35493|Streptophyta	S	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0010207,GO:0010287,GO:0015979,GO:0016020,GO:0016043,GO:0019684,GO:0022607,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0065003,GO:0071840	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_6578_2	3988.XP_002535618.1	9.94e-38	127.0	COG0740@1|root,KOG0840@2759|Eukaryota,37U4N@33090|Viridiplantae,3GICU@35493|Streptophyta,4JUJ9@91835|fabids	35493|Streptophyta	O	ATP-dependent Clp protease proteolytic	clpP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_6578_3	3988.XP_002523889.1	2.54e-42	140.0	COG0740@1|root,KOG0840@2759|Eukaryota,37XW7@33090|Viridiplantae,3GM1U@35493|Streptophyta	35493|Streptophyta	O	Encoded by	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_6578_5	4081.Solyc01g007470.1.1	4.02e-58	183.0	COG0292@1|root,KOG4707@2759|Eukaryota,37VVT@33090|Viridiplantae,3GJCY@35493|Streptophyta	35493|Streptophyta	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rpl20	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0031967,GO:0031975,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_6578_6	3702.ATCG00650.1	9.74e-49	157.0	KOG3162@1|root,KOG3162@2759|Eukaryota,37WM8@33090|Viridiplantae,3GJCQ@35493|Streptophyta	35493|Streptophyta	J	30S ribosomal protein S18, chloroplastic	rps18	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_6578_7	85681.XP_006435533.1	1.67e-36	123.0	COG0267@1|root,2S7HT@2759|Eukaryota,37WXH@33090|Viridiplantae,3GK94@35493|Streptophyta	35493|Streptophyta	J	50S ribosomal protein L33, chloroplastic	rpl33	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_6578_8	4081.Solyc01g067760.1.1	1.32e-24	93.2	2DZSX@1|root,2S79R@2759|Eukaryota,37WT4@33090|Viridiplantae,3GUGA@35493|Streptophyta,44UJ2@71274|asterids	35493|Streptophyta	C	Photosystem I reaction center subunit IX	-	-	-	ko:K02697	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PSI_PsaJ
k59_6578_10	13333.ERN02869	5.52e-54	171.0	2CHYC@1|root,2S3QA@2759|Eukaryota,37V66@33090|Viridiplantae,3GJP6@35493|Streptophyta	35493|Streptophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbE	-	-	ko:K02707,ko:K02713	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559,Cytochrom_B559a,PsbL
k59_6578_11	218851.Aquca_064_00073.1	2.99e-21	83.2	2E87T@1|root,2SEUE@2759|Eukaryota,37XI9@33090|Viridiplantae,3GMTY@35493|Streptophyta	35493|Streptophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02708	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559
k59_6578_12	15368.BRADI5G23870.1	4.32e-20	80.5	2C8JW@1|root,2SBI8@2759|Eukaryota,37XIV@33090|Viridiplantae,3GMK0@35493|Streptophyta,3M8NW@4447|Liliopsida,3IK71@38820|Poales	35493|Streptophyta	S	Photosystem II protein J	psbJ	-	-	ko:K02711	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbJ
k59_6578_14	15368.BRADI3G27332.1	8.38e-210	582.0	2CMAK@1|root,2QPT8@2759|Eukaryota,37MKA@33090|Viridiplantae,3GD5I@35493|Streptophyta,3KY9T@4447|Liliopsida,3IAPE@38820|Poales	35493|Streptophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N
k59_6578_15	72664.XP_006404488.1	6.01e-114	331.0	28IB5@1|root,2QV51@2759|Eukaryota,37SP0@33090|Viridiplantae,3GHPJ@35493|Streptophyta	35493|Streptophyta	U	May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake	cemA	-	-	-	-	-	-	-	-	-	-	-	CemA
k59_6578_16	4081.Solyc01g007360.2.1	2.09e-115	332.0	2CNI2@1|root,2QWGG@2759|Eukaryota,37P4I@33090|Viridiplantae,3GGGH@35493|Streptophyta,44MN2@71274|asterids	35493|Streptophyta	S	Ycf4	ycf4	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016043,GO:0019684,GO:0022607,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048564,GO:0051082,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Ycf4
k59_6578_17	3702.ATCG00510.1	1.15e-13	63.9	2E7JA@1|root,2SE4W@2759|Eukaryota,37XVE@33090|Viridiplantae,3GMGP@35493|Streptophyta	35493|Streptophyta	C	May help in the organization of the PsaL subunit	psaI	-	-	ko:K02696	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PSI_8
k59_6578_18	4081.Solyc01g007340.2.1	1.7e-245	687.0	COG4799@1|root,KOG0540@2759|Eukaryota,37NPW@33090|Viridiplantae,3GG0Z@35493|Streptophyta,44QTN@71274|asterids	35493|Streptophyta	H	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963,ko:K02696	ko00061,ko00195,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00195,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Carboxyl_trans,PSI_8
k59_135694_1	552811.Dehly_1586	1.48e-179	505.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_112220_1	1047013.AQSP01000056_gene1919	1.75e-89	279.0	COG0845@1|root,COG0845@2|Bacteria,2NR6A@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	VVA1500	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k59_159238_1	7668.SPU_008020-tr	1.63e-29	123.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,RVT_1
k59_100536_1	278963.ATWD01000001_gene3061	3.1e-36	128.0	COG1956@1|root,COG1956@2|Bacteria,3Y4UF@57723|Acidobacteria,2JJHH@204432|Acidobacteriia	204432|Acidobacteriia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
k59_71119_1	439235.Dalk_1624	9.17e-103	320.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
k59_88849_1	243231.GSU1469	2.54e-21	92.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria,43SWR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_88849_2	1121451.DESAM_10091	1.55e-39	139.0	COG1014@1|root,COG1014@2|Bacteria,1N53C@1224|Proteobacteria,42S8J@68525|delta/epsilon subdivisions,2WQ37@28221|Deltaproteobacteria,2MG5R@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Pyruvate ketoisovalerate oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_118068_1	880072.Desac_1563	7.31e-99	302.0	COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2MQYG@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_153261_1	158189.SpiBuddy_0038	8.1e-10	62.4	2CA4A@1|root,32RQK@2|Bacteria,2J92B@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
k59_129899_1	1395571.TMS3_0112850	3.34e-12	70.5	COG1846@1|root,COG1846@2|Bacteria,1NB2G@1224|Proteobacteria,1SED8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_12500_1	31234.CRE13126	1.39e-50	179.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_153268_2	44251.PDUR_00330	3.82e-33	124.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,26QMU@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_71146_1	649639.Bcell_0106	1.09e-36	128.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,1ZG84@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_135720_1	1379698.RBG1_1C00001G0581	6.15e-13	78.2	COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
k59_118102_1	717773.Thicy_0285	3.18e-12	72.8	COG3087@1|root,COG3210@1|root,COG3087@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales	72273|Thiotrichales	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	PATR
k59_12516_1	1089550.ATTH01000001_gene1531	2.45e-21	97.1	COG2911@1|root,COG3210@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
k59_12517_1	7070.TC007347-PA	9.24e-15	79.0	2DVX8@1|root,2S6P4@2759|Eukaryota,3A6J0@33154|Opisthokonta,3CPG6@33208|Metazoa,3E5M8@33213|Bilateria,42AP2@6656|Arthropoda,3T027@50557|Insecta	33208|Metazoa	L	Transposase protein	-	-	-	-	-	-	-	-	-	-	-	-	THAP,Tnp_P_element
k59_176920_2	7897.ENSLACP00000006184	8.44e-171	508.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,487FB@7711|Chordata,491IP@7742|Vertebrata	33208|Metazoa	-	-	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_18261_1	1121396.KB893100_gene4319	8.23e-45	165.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_124157_1	400682.PAC_15725361	5.92e-09	63.2	KOG1121@1|root,KOG1121@2759|Eukaryota,39RW9@33154|Opisthokonta,3BH13@33208|Metazoa	33208|Metazoa	L	RNA polymerase II regulatory region DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_176929_1	927704.SELR_26320	8.85e-32	127.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4H3W4@909932|Negativicutes	909932|Negativicutes	S	Ser Thr phosphatase family protein	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_182664_1	443143.GM18_2882	1.87e-131	388.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria	1224|Proteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k59_176936_1	1453505.JASY01000012_gene4222	5.67e-40	156.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia,2NUYY@237|Flavobacterium	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,MAM,PepSY,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,fn3
k59_82952_1	1121296.JONJ01000013_gene253	1.56e-66	214.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,21YMZ@1506553|Lachnoclostridium	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_40357_1	1242864.D187_006073	9.71e-116	347.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42Y66@68525|delta/epsilon subdivisions,2WU83@28221|Deltaproteobacteria,2YX71@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_40357_2	742766.HMPREF9455_03894	8.09e-26	111.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,2FPXY@200643|Bacteroidia,22X4I@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative modulator of DNA gyrase	tldD3	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_93084_1	555779.Dthio_PD0726	2.95e-64	199.0	2DMID@1|root,32RSF@2|Bacteria,1R0WM@1224|Proteobacteria,43D2G@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_28756_1	1235800.C819_00575	0.000112	47.0	COG5305@1|root,COG5305@2|Bacteria,1UXXF@1239|Firmicutes,249M9@186801|Clostridia,27I8V@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,DUF2141,PMT_2
k59_99578_2	760142.Hipma_0827	2.27e-23	100.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_99580_2	1121127.JAFA01000069_gene6116	5.38e-40	140.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VKCG@28216|Betaproteobacteria,1KH23@119060|Burkholderiaceae	28216|Betaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_157447_1	7668.SPU_019598-tr	9.8e-31	128.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_152107_1	685035.ADAE01000003_gene2839	5.62e-38	140.0	COG1403@1|root,COG1403@2|Bacteria,1RC9Y@1224|Proteobacteria,2U6X7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_93097_1	1379698.RBG1_1C00001G0159	2.15e-46	164.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_110816_1	7955.ENSDARP00000100375	4.4e-69	231.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria,48QHZ@7711|Chordata,497ZU@7742|Vertebrata,4A5U1@7898|Actinopterygii	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_34449_1	59689.fgenesh2_kg.7__385__AT4G36810.1	3.88e-61	201.0	COG0142@1|root,KOG0776@2759|Eukaryota,37N02@33090|Viridiplantae,3GDQS@35493|Streptophyta,3HSNJ@3699|Brassicales	35493|Streptophyta	H	Belongs to the FPP GGPP synthase family	-	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004161,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0007275,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009513,GO:0009536,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016740,GO:0016765,GO:0022414,GO:0032501,GO:0032502,GO:0042214,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043692,GO:0043693,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046246,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061458,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_69956_1	7029.ACYPI33401-PA	6.31e-30	122.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1,RVT_3
k59_99593_2	82654.Pse7367_3663	3.51e-12	68.2	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1G5@1117|Cyanobacteria,1H794@1150|Oscillatoriales	1117|Cyanobacteria	H	Tetratricopeptide repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
k59_128678_1	996637.SGM_3199	2.29e-53	172.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_69977_1	713586.KB900536_gene2750	5.24e-67	214.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,1T0C7@1236|Gammaproteobacteria,1X2MB@135613|Chromatiales	135613|Chromatiales	O	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_51351_1	765914.ThisiDRAFT_0766	1.35e-14	76.3	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1WWKF@135613|Chromatiales	135613|Chromatiales	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_104620_1	864069.MicloDRAFT_00004640	2.42e-39	147.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,2TRKA@28211|Alphaproteobacteria,1JWYG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_28784_1	6669.EFX62991	2.82e-19	78.6	2CZUP@1|root,2SBR2@2759|Eukaryota,396NA@33154|Opisthokonta,3CB0N@33208|Metazoa,3DS94@33213|Bilateria,423X4@6656|Arthropoda	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63706_1	1254432.SCE1572_18300	1.22e-06	50.4	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S34@68525|delta/epsilon subdivisions,2X5AY@28221|Deltaproteobacteria,2Z34Z@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_63706_2	309807.SRU_1354	6.05e-20	92.4	COG1441@1|root,COG1441@2|Bacteria,4PM5X@976|Bacteroidetes,1FJEH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
k59_140003_1	1453500.AT05_09080	3.02e-31	122.0	COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,1HZTM@117743|Flavobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_46171_1	1090320.KB900606_gene58	5.57e-73	228.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K2F6@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_128711_1	1192034.CAP_5454	4.6e-43	144.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
k59_69985_2	1379698.RBG1_1C00001G0965	1.05e-75	240.0	COG0174@1|root,COG0174@2|Bacteria,2NNY0@2323|unclassified Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_169896_1	641491.DND132_1852	1.63e-18	85.1	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2M87V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_169896_2	1265505.ATUG01000002_gene1286	5.89e-112	331.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MGJ@68525|delta/epsilon subdivisions,2WJ5E@28221|Deltaproteobacteria,2MHXN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_152164_1	1278073.MYSTI_07045	8.86e-54	186.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria	1224|Proteobacteria	KT	Transcriptional regulator	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K12146,ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_187067_3	706436.HMPREF9074_08150	2.52e-138	416.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HX4R@117743|Flavobacteriia,1EQ2H@1016|Capnocytophaga	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	betC_2	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_81723_1	1121028.ARQE01000010_gene973	4.13e-59	196.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2PJ5S@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_104655_1	8083.ENSXMAP00000019938	1.08e-57	194.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria,48QHZ@7711|Chordata,497ZU@7742|Vertebrata,4A5U1@7898|Actinopterygii	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_128750_1	1379858.N508_00286	4.07e-20	90.9	COG0455@1|root,COG0455@2|Bacteria,2GEQ7@200930|Deferribacteres	200930|Deferribacteres	N	AAA domain	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
k59_175138_1	7029.ACYPI071420-PA	1.05e-13	78.2	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa	33208|Metazoa	L	steroid hormone mediated signaling pathway	-	-	-	-	-	-	-	-	-	-	-	-	DUF1758,DUF1759,Peptidase_A17,rve
k59_51396_1	880073.Calab_0929	4.46e-49	169.0	COG0280@1|root,COG0280@2|Bacteria,2NP21@2323|unclassified Bacteria	2|Bacteria	C	Phosphate acetyl/butaryl transferase	pta	-	1.1.1.40,2.3.1.8	ko:K00029,ko:K00625,ko:K04020,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00172,M00357,M00579	R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_51396_2	1273103.NM10_07369	9.17e-19	84.7	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H2N9@909932|Negativicutes	909932|Negativicutes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_122715_1	2423.NA23_0200395	1.24e-42	151.0	COG0330@1|root,COG0330@2|Bacteria,2GC8F@200918|Thermotogae	200918|Thermotogae	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_175139_1	1397528.Q671_14960	7.99e-35	134.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales	135619|Oceanospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_164124_1	203124.Tery_0200	2.27e-78	251.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G4QD@1117|Cyanobacteria,1H88T@1150|Oscillatoriales	1117|Cyanobacteria	L	L COG3335 Transposase and inactivated derivatives	-	-	-	ko:K07494,ko:K07499	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_33
k59_75601_1	8083.ENSXMAP00000012258	2.35e-20	93.2	COG2801@1|root,KOG0017@2759|Eukaryota,38F2S@33154|Opisthokonta,3BI3C@33208|Metazoa	33208|Metazoa	L	Gypsy retrotransposon integrase-like protein	GIN1	-	-	-	-	-	-	-	-	-	-	-	SCAN,THAP,rve,zf-CCHC,zf-H2C2
k59_157506_1	10224.XP_006819132.1	1.87e-20	95.9	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta	33154|Opisthokonta	L	biological adhesion	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_63747_1	349521.HCH_03845	2.1e-22	100.0	COG0745@1|root,COG2203@1|root,COG5001@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_8,PAS_9,Response_reg
k59_93199_1	204669.Acid345_3482	1.7e-29	117.0	COG1360@1|root,COG1360@2|Bacteria,3Y47G@57723|Acidobacteria,2JI3E@204432|Acidobacteriia	204432|Acidobacteriia	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_152216_1	28532.XP_010532942.1	4e-37	141.0	COG1208@1|root,KOG1322@2759|Eukaryota,37N08@33090|Viridiplantae,3G9K1@35493|Streptophyta,3HW2T@3699|Brassicales	35493|Streptophyta	M	This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP- glucose from Glc-1-P and ATP	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_35024_29	1101195.Meth11DRAFT_0026	1.01e-34	141.0	COG0457@1|root,COG3914@1|root,COG4421@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,COG4421@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,2KMDJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glyco_transf_41,Methyltransf_12,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
k59_166327_1	400682.PAC_15702057	2.66e-89	293.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,zf-RVT
k59_119257_1	6412.HelroP182599	1.34e-24	108.0	2B1C7@1|root,2S0A1@2759|Eukaryota,3AEY4@33154|Opisthokonta,3CP8T@33208|Metazoa,3E5DC@33213|Bilateria	33208|Metazoa	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_72079_1	6087.XP_004209760.1	1.19e-15	80.5	COG5022@1|root,KOG0161@2759|Eukaryota	2759|Eukaryota	Z	motor activity	-	-	-	ko:K10352,ko:K10362	ko04530,map04530	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	Myosin_head,Myosin_tail_1
k59_60397_1	404589.Anae109_1855	9.81e-06	53.9	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_37173_1	6238.CBG25534	3.2e-47	169.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,4150V@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142483_1	356851.JOAN01000043_gene2751	2.3e-53	192.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4DGWQ@85008|Micromonosporales	201174|Actinobacteria	L	COG5659 FOG Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_95850_1	1191523.MROS_1404	2.67e-07	52.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_95866_1	439496.RBY4I_2275	1.06e-17	84.0	COG0123@1|root,COG0454@1|root,COG0123@2|Bacteria,COG0456@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	BQ	COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein	aphA	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_95866_2	690850.Desaf_2080	2.19e-65	217.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NAQ@68525|delta/epsilon subdivisions,2WJPX@28221|Deltaproteobacteria,2M845@213115|Desulfovibrionales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
k59_166361_1	926561.KB900618_gene276	9.81e-21	89.0	298ZI@1|root,2ZW3A@2|Bacteria,1V7FU@1239|Firmicutes,24ID8@186801|Clostridia,3WAVV@53433|Halanaerobiales	186801|Clostridia	S	ECF transporter, substrate-specific component	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF_trnsprt
k59_166361_2	1051632.TPY_1308	1.15e-11	70.1	COG0500@1|root,COG0589@1|root,COG0589@2|Bacteria,COG2226@2|Bacteria,1V5VE@1239|Firmicutes,25KUU@186801|Clostridia,3WDNW@538999|Clostridiales incertae sedis	186801|Clostridia	Q	Methyltransferase domain	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_25465_1	1232437.KL662020_gene705	5.75e-65	212.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_83938_1	871584.D9ZNH5_9CAUD	7.04e-38	141.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae	10699|Siphoviridae	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60435_1	639282.DEFDS_1067	2.09e-116	351.0	COG1012@1|root,COG1012@2|Bacteria,2GEJJ@200930|Deferribacteres	200930|Deferribacteres	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_101451_3	3880.AES58519	1.08e-111	335.0	COG1008@1|root,KOG4845@2759|Eukaryota,37KP8@33090|Viridiplantae,3GEAS@35493|Streptophyta,4JUKV@91835|fabids	35493|Streptophyta	C	Proton-conducting membrane transporter	nad4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03881	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_101451_4	3988.XP_002534687.1	1.82e-104	312.0	COG1008@1|root,KOG4845@2759|Eukaryota,37KP8@33090|Viridiplantae,3GEAS@35493|Streptophyta,4JUKV@91835|fabids	35493|Streptophyta	C	Proton-conducting membrane transporter	nad4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03881	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_107381_1	1195236.CTER_4772	3.43e-64	223.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_178042_2	518766.Rmar_0047	1.23e-116	358.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1FJ3A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_54611_1	1463825.JNXC01000014_gene7677	3.3e-22	99.4	COG1470@1|root,COG1470@2|Bacteria,2I2YC@201174|Actinobacteria,4EDR5@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,Melibiase_2_C,NPCBM,NPCBM_assoc
k59_89690_1	1191523.MROS_0285	1.01e-28	124.0	2E09V@1|root,32VXB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136931_1	537013.CLOSTMETH_02654	4.51e-17	83.2	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_119304_1	497964.CfE428DRAFT_2658	6.08e-81	249.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_160598_1	395961.Cyan7425_2666	1.93e-26	111.0	2DBFF@1|root,2Z8YA@2|Bacteria,1G2KB@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_78085_1	118168.MC7420_2915	1.63e-18	90.1	COG1413@1|root,COG4995@1|root,COG1413@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	CHAT,DUF1822,HEAT_2,HEAT_PBS,NACHT,Peptidase_M9,Peptidase_M9_N
k59_83953_1	419665.Maeo_1469	0.000822	43.5	COG1146@1|root,arCOG00959@2157|Archaea,2XZY3@28890|Euryarchaeota,23R9B@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
k59_171879_1	7029.ACYPI47019-PA	6.37e-28	118.0	28IIP@1|root,2QQVP@2759|Eukaryota,39TA7@33154|Opisthokonta,3CNWS@33208|Metazoa,3D3DK@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_1673_1	1163617.SCD_n01692	5.05e-56	189.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_125135_1	163908.KB235896_gene4775	3.08e-153	442.0	COG5433@1|root,COG5433@2|Bacteria,1G2IT@1117|Cyanobacteria,1HREI@1161|Nostocales	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_154369_2	349161.Dred_2520	5.68e-54	175.0	COG0537@1|root,COG0537@2|Bacteria,1V5CH@1239|Firmicutes,24U56@186801|Clostridia,261NA@186807|Peptococcaceae	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
k59_160606_1	7739.XP_002606696.1	5.6e-140	437.0	2D18H@1|root,2SH4Q@2759|Eukaryota,3AJ24@33154|Opisthokonta,3BYE1@33208|Metazoa,3DD8X@33213|Bilateria,48R8R@7711|Chordata	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_7704_1	1131269.AQVV01000013_gene1751	2.06e-84	267.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
k59_89695_4	639282.DEFDS_P119	9.98e-14	79.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_183551_1	479437.Elen_1688	1.42e-13	69.3	COG0425@1|root,COG0425@2|Bacteria,2HUYT@201174|Actinobacteria,4CW0P@84998|Coriobacteriia	84998|Coriobacteriia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
k59_183551_2	643473.KB235930_gene4490	0.000141	43.9	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1G0T4@1117|Cyanobacteria,1HM63@1161|Nostocales	1117|Cyanobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
k59_113165_1	1124780.ANNU01000078_gene769	2.82e-46	164.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
k59_101486_1	945713.IALB_0266	1.61e-104	315.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
k59_166417_1	398720.MED217_04747	6.89e-44	159.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia,2XI43@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_37222_3	3694.POPTR_0005s02360.1	1.24e-19	93.6	2E1M0@1|root,2S8XN@2759|Eukaryota,37WG5@33090|Viridiplantae,3GK4P@35493|Streptophyta,4JQZC@91835|fabids	35493|Streptophyta	S	Plant mobile domain	-	-	-	-	-	-	-	-	-	-	-	-	PMD
k59_186711_1	7897.ENSLACP00000014528	3.24e-40	147.0	KOG1121@1|root,KOG1121@2759|Eukaryota,39WQ2@33154|Opisthokonta,3BJ35@33208|Metazoa,3CVNM@33213|Bilateria,48AHQ@7711|Chordata,49589@7742|Vertebrata	33208|Metazoa	L	protein dimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,zf-BED
k59_81283_1	397287.C807_00824	2.7e-09	60.1	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,27MSD@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k59_81283_2	903818.KI912268_gene3098	6.5e-10	55.1	COG0333@1|root,COG0333@2|Bacteria,3Y5W0@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k59_157173_1	1304872.JAGC01000005_gene2126	8.31e-43	156.0	COG3118@1|root,COG3118@2|Bacteria,1QTZ9@1224|Proteobacteria,43D80@68525|delta/epsilon subdivisions,2X8EN@28221|Deltaproteobacteria,2MHHB@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
k59_28505_1	1379698.RBG1_1C00001G1445	4.97e-59	205.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
k59_63356_1	1211814.CAPG01000029_gene1453	1.9e-07	57.8	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,1ZRKY@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
k59_40113_11	1231377.C426_1959	1.12e-09	62.0	COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HKCF@91061|Bacilli,1YCHD@1357|Lactococcus	91061|Bacilli	L	Terminase small subunit	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Terminase_2
k59_169609_1	502025.Hoch_1127	4.65e-36	137.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YTTS@29|Myxococcales	28221|Deltaproteobacteria	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_110546_1	400682.PAC_15711139	1.11e-35	148.0	KOG1721@1|root,KOG1721@2759|Eukaryota,39XVR@33154|Opisthokonta,3BMWQ@33208|Metazoa	33208|Metazoa	S	ZnF_TTF	ZNF862	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,KRAB
k59_45841_1	643648.Slip_2249	1.23e-70	220.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42JS9@68298|Syntrophomonadaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_169617_1	377629.TERTU_4338	8.49e-30	116.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,2PN00@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	H	Ferrochelatase	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_169617_2	1125973.JNLC01000010_gene1090	7.31e-07	51.6	COG2072@1|root,COG2072@2|Bacteria,1QW8X@1224|Proteobacteria,2TWTE@28211|Alphaproteobacteria,3K6P6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
k59_157193_1	288000.BBta_5329	2.28e-14	73.9	COG0784@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JR0R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,MASE4,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_157193_2	1121441.AUCX01000023_gene1813	2.46e-16	80.5	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R6F@68525|delta/epsilon subdivisions,2WN2B@28221|Deltaproteobacteria,2M95Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
k59_87135_1	1379698.RBG1_1C00001G1194	1.24e-24	109.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
k59_10756_2	204669.Acid345_3097	2.06e-63	205.0	COG0451@1|root,COG0451@2|Bacteria,3Y3ZG@57723|Acidobacteria,2JHT7@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_81326_1	1313304.CALK_2369	5.5e-58	190.0	COG1774@1|root,COG1774@2|Bacteria	2|Bacteria	S	domain protein	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	PSP1
k59_145983_1	1410632.JHWW01000009_gene2468	3.37e-05	50.4	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,27KT9@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	Type II secretion system (T2SS), protein E, N-terminal domain	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_87142_1	1167006.UWK_00616	3.28e-06	52.8	COG2334@1|root,COG2334@2|Bacteria,1Q18Y@1224|Proteobacteria,42PIW@68525|delta/epsilon subdivisions,2WK5A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_16973_1	1235799.C818_03671	1.19e-08	53.1	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia,27Q6X@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_169634_1	579405.Dd703_1472	2.86e-16	83.6	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,2JDZ9@204037|Dickeya	1236|Gammaproteobacteria	U	General secretion pathway protein F	gspF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_151795_2	1454004.AW11_01406	1.61e-05	47.4	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2VNKF@28216|Betaproteobacteria	28216|Betaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_139821_2	697284.ERIC2_c03930	1.96e-35	134.0	COG0860@1|root,COG0860@2|Bacteria,1V4B9@1239|Firmicutes,4HGZ9@91061|Bacilli,2708N@186822|Paenibacillaceae	91061|Bacilli	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1,SPOR
k59_122405_1	3880.AES58588	1.47e-28	114.0	2CY54@1|root,2S23H@2759|Eukaryota,3896T@33090|Viridiplantae,3GY43@35493|Streptophyta,4JWBW@91835|fabids	35493|Streptophyta	S	Ribosomal protein S10p/S20e	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_122405_3	3880.AES58577	6.89e-92	296.0	COG0056@1|root,COG0356@1|root,COG1622@1|root,KOG1353@2759|Eukaryota,KOG4665@2759|Eukaryota,KOG4767@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta,4JSJY@91835|fabids	35493|Streptophyta	C	ATP synthase	atp1	-	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,COX2_TM
k59_122405_8	4113.PGSC0003DMT400021489	5.69e-09	55.5	COG2009@1|root,KOG0449@2759|Eukaryota,37WX8@33090|Viridiplantae,3GKZI@35493|Streptophyta,44TH9@71274|asterids	35493|Streptophyta	G	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdh3	GO:0005575,GO:0005622,GO:0005623,GO:0016020,GO:0032991,GO:0044424,GO:0044425,GO:0044464,GO:0045273,GO:0070469,GO:0098796,GO:0098803	-	ko:K00236	ko00020,ko00190,ko01100,ko01110,ko01120,ko01130,ko01200,ko04714,ko04932,ko05010,ko05012,ko05016,map00020,map00190,map01100,map01110,map01120,map01130,map01200,map04714,map04932,map05010,map05012,map05016	M00009,M00011,M00148	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	HSP70,Sdh_cyt
k59_122405_9	29730.Gorai.001G161700.1	2.52e-189	532.0	COG1622@1|root,KOG4767@2759|Eukaryota,37T4F@33090|Viridiplantae,3GGAX@35493|Streptophyta	35493|Streptophyta	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1	cox2	GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	ko:K02261	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX2,COX2_TM
k59_99328_2	1131814.JAFO01000001_gene2970	3.95e-44	160.0	COG4974@1|root,COG4974@2|Bacteria,1P8X9@1224|Proteobacteria,2U1X9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_69711_1	1121396.KB893046_gene3287	0.000618	43.9	COG1846@1|root,COG1846@2|Bacteria,1N75F@1224|Proteobacteria,42VDI@68525|delta/epsilon subdivisions,2WR80@28221|Deltaproteobacteria,2MK08@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_69711_2	1267535.KB906767_gene1609	3.96e-16	82.4	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
k59_10780_1	388413.ALPR1_06960	5.4e-26	103.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,47JM3@768503|Cytophagia	976|Bacteroidetes	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_10780_2	235279.HH_1486	2.11e-05	51.2	COG0357@1|root,COG0357@2|Bacteria,1NAFK@1224|Proteobacteria,43B6H@68525|delta/epsilon subdivisions,2YT64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_10780_3	177439.DP0852	1e-17	88.2	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,2MJBM@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_110575_1	7029.ACYPI22826-PA	5.81e-35	140.0	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa,3DKI7@33213|Bilateria,422A5@6656|Arthropoda,3SQP0@50557|Insecta	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_134037_2	411474.COPEUT_01399	2.43e-17	85.9	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_151826_1	215358.XP_010745375.1	7.35e-29	122.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PNMA,RVT_1,rve
k59_116343_1	118166.JH976537_gene3160	6.9e-66	220.0	COG0471@1|root,COG0471@2|Bacteria,1G0FA@1117|Cyanobacteria,1H7KC@1150|Oscillatoriales	1117|Cyanobacteria	P	Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_134638_1	243233.MCA0805	4.66e-86	284.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XE6F@135618|Methylococcales	135618|Methylococcales	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_157748_1	366602.Caul_4644	2.15e-10	66.6	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2KEYV@204458|Caulobacterales	204458|Caulobacterales	M	AsmA family	-	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
k59_175481_2	1047013.AQSP01000140_gene2452	7.46e-104	312.0	COG0473@1|root,COG0473@2|Bacteria,2NNUM@2323|unclassified Bacteria	2|Bacteria	CE	Isocitrate/isopropylmalate dehydrogenase	dlpA	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh,MoCF_biosynth,RraA-like
k59_105341_1	439235.Dalk_1928	4.41e-117	345.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_23095_1	96561.Dole_1268	7.06e-62	211.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MHQW@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_175836_1	7668.SPU_008377-tr	1.46e-56	204.0	COG0666@1|root,COG2801@1|root,KOG3736@1|root,KOG0017@2759|Eukaryota,KOG0504@2759|Eukaryota,KOG3737@2759|Eukaryota,39JVB@33154|Opisthokonta,3BJQ0@33208|Metazoa,3CXAM@33213|Bilateria	33208|Metazoa	M	ankyrin repeat and SOCS	ASB3	GO:0000151,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0032446,GO:0032991,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044424,GO:0044444,GO:0044464,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1902494,GO:1990234	-	ko:K10325	-	-	-	-	ko00000,ko04121	-	-	-	Ank_2,Ank_3,Ank_4,SOCS_box
k59_52086_1	1499967.BAYZ01000059_gene4763	2.19e-15	77.0	COG1633@1|root,COG1633@2|Bacteria,2NQ7M@2323|unclassified Bacteria	2|Bacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_23096_1	380358.XALC_0772	1.94e-51	184.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_64488_1	177437.HRM2_10690	1.77e-82	257.0	COG0674@1|root,COG0674@2|Bacteria,1MWCI@1224|Proteobacteria,42NJY@68525|delta/epsilon subdivisions,2WIW3@28221|Deltaproteobacteria,2MHPN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorA	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1307	PFOR_II,POR_N
k59_64488_2	1121396.KB893071_gene1268	3.18e-17	78.6	COG1013@1|root,COG1013@2|Bacteria,1N0HY@1224|Proteobacteria,42MTM@68525|delta/epsilon subdivisions,2WJS6@28221|Deltaproteobacteria,2MIRW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_11698_1	546262.NEICINOT_04882	1.79e-43	156.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VUQN@28216|Betaproteobacteria,2KSW9@206351|Neisseriales	206351|Neisseriales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_140721_5	981085.XP_010086549.1	1.54e-50	161.0	COG1007@1|root,KOG4668@2759|Eukaryota,37WWH@33090|Viridiplantae,3GKTY@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_140721_6	4577.GRMZM5G804671_P01	5.04e-10	58.5	2CF62@1|root,2R4SU@2759|Eukaryota,385N3@33090|Viridiplantae,3GTKF@35493|Streptophyta,3M6GM@4447|Liliopsida,3IQCQ@38820|Poales	4577.GRMZM5G804671_P01|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140721_7	4577.GRMZM2G356639_P01	7.12e-14	68.9	2CF62@1|root,2R4SU@2759|Eukaryota,385N3@33090|Viridiplantae,3GTKF@35493|Streptophyta,3M6GM@4447|Liliopsida,3IQCQ@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140721_8	981085.XP_010086547.1	5.56e-56	174.0	COG1007@1|root,KOG4668@2759|Eukaryota,37WKT@33090|Viridiplantae,3GKHT@35493|Streptophyta,4JUQ2@91835|fabids	35493|Streptophyta	C	Proton-conducting membrane transporter	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_116732_1	986075.CathTA2_1034	4.97e-105	320.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_76307_1	1120988.AXWV01000071_gene1987	0.000645	43.9	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1Y6PY@135624|Aeromonadales	135624|Aeromonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_140762_2	985867.AEWF01000004_gene108	6.11e-42	152.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,47EU8@766|Rickettsiales	766|Rickettsiales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	abcT1	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
k59_175910_1	41431.PCC8801_3304	7.04e-55	186.0	COG1864@1|root,COG1864@2|Bacteria,1GKGW@1117|Cyanobacteria,3KJW9@43988|Cyanothece	1117|Cyanobacteria	L	DNA RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
k59_47348_1	1379698.RBG1_1C00001G1265	5.72e-116	347.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_117785_1	1121472.AQWN01000002_gene2301	6.59e-78	261.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_17987_1	1388763.O165_008780	1.3e-06	53.9	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S69B@1236|Gammaproteobacteria,1YXTE@136845|Pseudomonas putida group	1236|Gammaproteobacteria	U	secretion pathway protein	gspG_2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_47355_1	69014.TK0290	6.68e-23	98.6	COG1180@1|root,arCOG00952@2157|Archaea,2XZW0@28890|Euryarchaeota,244ZY@183968|Thermococci	183968|Thermococci	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_47355_2	309798.COPRO5265_1565	5.24e-13	68.9	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,42EP9@68295|Thermoanaerobacterales	186801|Clostridia	C	formate C-acetyltransferase glycine radical	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k59_17990_1	161156.JQKW01000008_gene449	6.55e-30	120.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_135444_1	1223523.H340_23763	3.85e-44	171.0	COG1376@1|root,COG2304@1|root,COG1376@2|Bacteria,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
k59_100219_1	69395.JQLZ01000002_gene1021	5.23e-79	262.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,2TRU5@28211|Alphaproteobacteria,2KI50@204458|Caulobacterales	204458|Caulobacterales	EI	Allophanate hydrolase subunit 2	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_52599_1	886293.Sinac_3821	2.31e-19	90.9	COG0515@1|root,COG0515@2|Bacteria,2IYEQ@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_52658_1	65393.PCC7424_0474	1.25e-11	65.9	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria,3KHDA@43988|Cyanothece	1117|Cyanobacteria	P	Sodium/calcium exchanger protein	ecm27	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_52658_2	43229.XP_007727904.1	7.04e-07	52.4	COG1028@1|root,KOG0725@2759|Eukaryota,38I37@33154|Opisthokonta,3NU20@4751|Fungi,3QR7D@4890|Ascomycota,20FGA@147545|Eurotiomycetes,3MU0K@451870|Chaetothyriomycetidae	4751|Fungi	Q	Gluconate 5-dehydrogenase	ARDH	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044238,GO:0047038,GO:0055114,GO:0071704	1.1.1.250	ko:K17738	ko00040,ko01100,map00040,map01100	-	R07134	RC00102	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_52700_1	398767.Glov_0977	1.55e-18	85.9	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
k59_52700_2	1122172.KB890259_gene959	1.63e-98	308.0	COG1164@1|root,COG1164@2|Bacteria,378MH@32066|Fusobacteria	32066|Fusobacteria	E	Psort location Cytoplasmic, score	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_52706_1	439235.Dalk_1464	1.45e-55	184.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_117115_1	1379698.RBG1_1C00001G1479	2.52e-78	248.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2NNX4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	CBS,IMPDH,NMO
k59_117200_1	1192034.CAP_0267	2.03e-14	78.2	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1MWVZ@1224|Proteobacteria,438G1@68525|delta/epsilon subdivisions,2X3QZ@28221|Deltaproteobacteria,2YWVV@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
k59_117374_1	290397.Adeh_2774	2.15e-24	107.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Flg_new,Glug,WxL
k59_117389_1	1150599.MPHLEI_25456	8.84e-20	95.9	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,233BZ@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_88671_2	1094980.Mpsy_0430	6.82e-15	71.2	arCOG06819@1|root,arCOG06819@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100432_2	96561.Dole_1742	8.79e-08	58.2	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42TFM@68525|delta/epsilon subdivisions,2WPBE@28221|Deltaproteobacteria,2MK7R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_159117_3	742823.HMPREF9465_00185	1.23e-19	87.0	COG3935@1|root,COG3935@2|Bacteria,1MXB6@1224|Proteobacteria	1224|Proteobacteria	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_597_2	6412.HelroP160923	3.9e-74	255.0	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa,3E5DG@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6520_1	1122621.ATZA01000016_gene3778	3.69e-50	173.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1IPDZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_153128_1	6412.HelroP178679	3.78e-19	91.7	2AI1Z@1|root,2RZ3S@2759|Eukaryota,3A87B@33154|Opisthokonta,3BV9Z@33208|Metazoa,3DEC7@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_59286_2	215803.DB30_0733	8.72e-25	95.9	COG2840@1|root,COG2840@2|Bacteria,1QX48@1224|Proteobacteria,43BWQ@68525|delta/epsilon subdivisions,2X77I@28221|Deltaproteobacteria,2Z3DP@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_147314_1	56110.Oscil6304_2815	5e-09	63.5	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
k59_106336_1	489825.LYNGBM3L_57630	1.36e-10	68.6	COG0438@1|root,COG0438@2|Bacteria,1G0EX@1117|Cyanobacteria,1H9C2@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_59294_1	986075.CathTA2_1558	6.19e-48	174.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_24121_1	234267.Acid_0646	5.39e-109	320.0	COG1484@1|root,COG1484@2|Bacteria,3Y6NW@57723|Acidobacteria	57723|Acidobacteria	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_141509_1	459349.CLOAM0610	6.58e-24	112.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_24130_1	246197.MXAN_4445	1.62e-19	92.8	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,43BX3@68525|delta/epsilon subdivisions,2X77W@28221|Deltaproteobacteria,2YUH7@29|Myxococcales	28221|Deltaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
k59_18157_1	272844.PAB0255	1.02e-14	76.3	COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,242ZK@183968|Thermococci	183968|Thermococci	J	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_65187_1	1396418.BATQ01000117_gene4592	8.36e-10	65.1	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	estA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Lipase_GDSL_2
k59_124026_1	1279009.ADICEAN_01119	5.3e-05	53.1	COG3419@1|root,COG4935@1|root,COG3419@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	DUF4114,Reprolysin_4
k59_176788_1	338963.Pcar_1381	2.27e-100	300.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,42MM6@68525|delta/epsilon subdivisions,2WJ53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_135625_1	7425.NV26146-PA	5.27e-16	86.3	28M7P@1|root,2QTQS@2759|Eukaryota,39Z9X@33154|Opisthokonta,3BNGS@33208|Metazoa,3D442@33213|Bilateria,42C0F@6656|Arthropoda,3SW4J@50557|Insecta,46MTI@7399|Hymenoptera	33208|Metazoa	S	cellular response to interferon-beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141541_1	319003.Bra1253DRAFT_02729	7.52e-33	132.0	COG1396@1|root,COG3093@1|root,COG1396@2|Bacteria,COG3093@2|Bacteria,1MV9M@1224|Proteobacteria,2U2WE@28211|Alphaproteobacteria,3JVMW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_100482_1	1121024.AUCD01000091_gene2155	5.15e-51	173.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,27FTX@186828|Carnobacteriaceae	91061|Bacilli	C	FAD binding domain	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_165238_1	945713.IALB_2868	3.01e-95	292.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_24155_1	7029.ACYPI080587-PA	5.71e-05	52.8	KOG1121@1|root,KOG1121@2759|Eukaryota	2759|Eukaryota	E	protein dimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_165240_1	5039.XP_002620072.1	2.43e-34	132.0	2AFWN@1|root,2RYYK@2759|Eukaryota,3A0HV@33154|Opisthokonta,3P3MV@4751|Fungi,3QZE1@4890|Ascomycota	4751|Fungi	S	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
k59_112145_1	1379698.RBG1_1C00001G1544	1.77e-105	322.0	COG4191@1|root,COG4191@2|Bacteria,2NPC5@2323|unclassified Bacteria	2|Bacteria	T	Integral membrane sensor signal transduction histidine kinase	vicK	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
k59_35934_1	1254432.SCE1572_30795	4.33e-44	169.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MX4K@1224|Proteobacteria,42WVW@68525|delta/epsilon subdivisions,2X77J@28221|Deltaproteobacteria,2YUN6@29|Myxococcales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_88763_1	518766.Rmar_0582	2.7e-49	178.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,1FJ02@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k59_65214_1	1379698.RBG1_1C00001G1819	1.05e-50	183.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_77012_2	1379698.RBG1_1C00001G0428	5.69e-25	105.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS
k59_18194_1	8049.ENSGMOP00000009375	1.28e-85	285.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,487FB@7711|Chordata,491IP@7742|Vertebrata,4A56D@7898|Actinopterygii	33208|Metazoa	S	kiaa1586	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_12426_1	504472.Slin_4595	9.32e-34	135.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47N0R@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_77022_1	690850.Desaf_2054	1.37e-51	179.0	COG0530@1|root,COG0530@2|Bacteria,1QDUB@1224|Proteobacteria,435JZ@68525|delta/epsilon subdivisions,2WZY9@28221|Deltaproteobacteria,2M8JC@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_134448_1	7897.ENSLACP00000010249	1.41e-66	222.0	2F3H3@1|root,2T4GG@2759|Eukaryota,38Y87@33154|Opisthokonta,3C5U5@33208|Metazoa,3DM5H@33213|Bilateria	7897.ENSLACP00000010249|-	S	Protein of unknown function (DUF 659)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34671_1	1282876.BAOK01000001_gene1484	3.83e-52	178.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria,4BS1W@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_34671_2	344747.PM8797T_05545	1.25e-10	61.6	COG2318@1|root,COG2318@2|Bacteria,2J3KN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
k59_164214_1	272123.Anacy_2404	1.02e-46	171.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_87637_2	1304885.AUEY01000022_gene3408	4.69e-40	137.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MJTB@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_109546_2	880074.BARVI_02705	3.83e-11	65.9	COG2755@1|root,COG2755@2|Bacteria,4NHBT@976|Bacteroidetes,2G2NP@200643|Bacteroidia,22XYM@171551|Porphyromonadaceae	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Lipase_GDSL_2
k59_39265_1	10224.XP_006825930.1	1.97e-90	297.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_74257_1	6087.XP_004210714.1	9.57e-13	70.1	KOG1121@1|root,KOG1121@2759|Eukaryota,3A1BV@33154|Opisthokonta,3BQ1H@33208|Metazoa	33208|Metazoa	L	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,zf-BED
k59_44804_1	1120966.AUBU01000005_gene3851	2.98e-27	115.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,47RCS@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_144896_1	763034.HMPREF9446_01100	1.99e-142	433.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,2FM5N@200643|Bacteroidia,4AKZF@815|Bacteroidaceae	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_85978_2	1430440.MGMSRv2_0771	1.49e-05	51.2	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2UA8J@28211|Alphaproteobacteria,2JX09@204441|Rhodospirillales	204441|Rhodospirillales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_144910_1	96561.Dole_1595	4.73e-96	296.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MHVD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_98340_1	1379698.RBG1_1C00001G0633	3.92e-29	109.0	COG2172@1|root,COG2172@2|Bacteria,2NQ1S@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
k59_98340_2	1246995.AFR_01880	4.53e-07	50.8	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,4DE05@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
k59_62396_2	1207063.P24_15029	2.57e-08	54.7	COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68635_1	368407.Memar_1465	0.000611	44.3	COG2896@1|root,arCOG00930@2157|Archaea,2XT7P@28890|Euryarchaeota,2N9FQ@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_3963_1	1459636.NTE_00601	4.11e-39	145.0	COG3958@1|root,arCOG01051@2157|Archaea,41SEP@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_168617_1	880071.Fleli_1980	9.64e-08	62.4	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
k59_39289_1	1485544.JQKP01000015_gene2064	1.75e-31	127.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_9723_1	563008.HMPREF0665_02679	2.66e-08	56.2	COG3516@1|root,COG3516@2|Bacteria,4NKZY@976|Bacteroidetes,2FQCM@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VipA
k59_109576_1	237368.SCABRO_02636	4.72e-50	170.0	COG1912@1|root,COG1912@2|Bacteria,2IZNZ@203682|Planctomycetes	203682|Planctomycetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
k59_50426_1	998674.ATTE01000001_gene3216	1.26e-69	221.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RY2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_109578_1	247490.KSU1_C1660	1.92e-19	87.8	COG1943@1|root,COG1943@2|Bacteria,2J110@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_50427_1	1047013.AQSP01000139_gene2392	4.9e-76	241.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_91789_1	1147.D082_27330	2.27e-06	49.7	COG0468@1|root,COG0468@2|Bacteria,1G14C@1117|Cyanobacteria,1H4PD@1142|Synechocystis	1117|Cyanobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_109586_1	696281.Desru_2597	2.39e-31	122.0	COG2181@1|root,COG2181@2|Bacteria,1TTC6@1239|Firmicutes,24FA6@186801|Clostridia,261C0@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_74310_1	1242969.ATCC51562_611	9.58e-14	80.5	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_74315_1	329726.AM1_6037	3.98e-58	191.0	COG3547@1|root,COG3547@2|Bacteria,1G1N1@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase is116 is110 is902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_144953_2	1379698.RBG1_1C00001G1804	5.3e-29	107.0	2E8AI@1|root,332PD@2|Bacteria,2NRHQ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_180358_2	159450.NH14_00775	4.62e-45	164.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2VM0Z@28216|Betaproteobacteria,1K0MP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_114807_1	1121403.AUCV01000026_gene2326	1.18e-26	114.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MI13@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_56941_1	6211.A0A068Y3R8	1.05e-21	93.6	2DZJG@1|root,2S72Z@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27602_1	248742.XP_005643649.1	4.99e-69	215.0	COG0221@1|root,KOG1626@2759|Eukaryota,37R74@33090|Viridiplantae,34J91@3041|Chlorophyta	3041|Chlorophyta	C	soluble inorganic pyrophosphatase	-	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_74328_2	1123008.KB905697_gene3224	1.28e-52	182.0	COG1305@1|root,COG1305@2|Bacteria,4NGQ2@976|Bacteroidetes,2FMDR@200643|Bacteroidia,22YNT@171551|Porphyromonadaceae	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,Transglut_core
k59_9736_1	93059.P9211_07681	1.02e-29	116.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
k59_127397_1	7668.SPU_020098-tr	8.16e-20	90.1	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_185721_1	243231.GSU1832	8.75e-43	150.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k59_74340_1	1537994.JQFW01000007_gene2875	4.99e-46	164.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria,46BP8@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_121451_1	945713.IALB_1293	3.92e-23	102.0	COG1523@1|root,COG4935@1|root,COG1523@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PUD,Reprolysin_4
k59_86053_1	1408311.JNJM01000005_gene1589	7.38e-89	288.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,2PRP2@265975|Oribacterium	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_68683_2	1282361.ABAC402_10020	5.86e-47	154.0	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,2UAE3@28211|Alphaproteobacteria,2KJJP@204458|Caulobacterales	204458|Caulobacterales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_68683_3	1123376.AUIU01000012_gene1444	1.08e-20	90.9	COG0156@1|root,COG0156@2|Bacteria,3J0XU@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_173936_1	335541.Swol_2269	1.02e-41	157.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,SEFIR,TIR_2
k59_150910_1	1047013.AQSP01000132_gene1733	2.18e-66	226.0	COG0038@1|root,COG0038@2|Bacteria,2NPC4@2323|unclassified Bacteria	2|Bacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
k59_9765_1	383372.Rcas_3962	7.02e-27	112.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Laminin_G_3,Pkinase
k59_98409_1	8153.XP_005950830.1	1.85e-38	144.0	28PS4@1|root,2QWEM@2759|Eukaryota,39STS@33154|Opisthokonta,3BM2D@33208|Metazoa,3D4ZE@33213|Bilateria,48DF9@7711|Chordata,498UM@7742|Vertebrata,4A4ND@7898|Actinopterygii	33208|Metazoa	S	piggyBac transposable element-derived protein 4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_168676_1	153721.MYP_3637	4.58e-08	60.8	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
k59_9769_1	234267.Acid_2294	0.000167	50.4	COG0745@1|root,COG2202@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_50464_1	1379698.RBG1_1C00001G1750	2.15e-67	218.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
k59_150912_1	7668.SPU_010235-tr	3.27e-141	454.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta	33154|Opisthokonta	L	biological adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,DUF1758,DUF1759,Peptidase_A17,rve
k59_2836_1	2850.Phatr49505	3.01e-135	400.0	COG3033@1|root,2QU0C@2759|Eukaryota	2759|Eukaryota	E	lyase activity	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase,Trp_DMAT
k59_132018_1	545696.HOLDEFILI_02912	3.5e-31	125.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes	1239|Firmicutes	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
k59_14743_1	7029.ACYPI069797-PA	3.89e-29	120.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RNase_H,RVT_1
k59_108572_1	1121396.KB893077_gene747	3.86e-77	240.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
k59_79255_1	694440.JOMF01000004_gene1228	2.01e-90	280.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
k59_85148_1	1210884.HG799473_gene15045	2.52e-44	157.0	COG1706@1|root,COG1706@2|Bacteria,2IZDW@203682|Planctomycetes	203682|Planctomycetes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_43787_1	228410.NE2238	5.54e-80	239.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2VTIQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_179266_1	56780.SYN_00390	7.87e-70	223.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,42RYH@68525|delta/epsilon subdivisions,2WNT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_90892_1	1150469.RSPPHO_03277	4.7e-23	95.9	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_90892_2	933262.AXAM01000010_gene1397	7.62e-35	121.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,42S33@68525|delta/epsilon subdivisions,2WNKG@28221|Deltaproteobacteria,2MJWX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102567_1	10224.XP_006811646.1	5.88e-13	79.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A4K9@33154|Opisthokonta,3BSC4@33208|Metazoa,3D93E@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_90895_1	7029.ACYPI45338-PA	1.02e-92	306.0	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa,3DKI7@33213|Bilateria	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_43794_1	521045.Kole_0200	1.3e-46	162.0	COG0004@1|root,COG0004@2|Bacteria,2GD3C@200918|Thermotogae	200918|Thermotogae	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_73256_1	1408323.JQKK01000006_gene540	7.87e-13	75.9	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,27TC6@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K20486	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Big_2,Peptidase_S8
k59_126295_1	634497.HAH_1388	1.66e-17	81.3	COG1670@1|root,arCOG00842@2157|Archaea,2XVC6@28890|Euryarchaeota,23TBU@183963|Halobacteria	183963|Halobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	hat2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_126295_2	375286.mma_0606	1.11e-26	110.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2VHAB@28216|Betaproteobacteria,4729B@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_97282_1	400682.PAC_15702057	2.16e-58	206.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,zf-RVT
k59_55802_1	1197477.IA57_11075	0.000282	46.6	COG2885@1|root,COG3209@1|root,COG3227@1|root,COG3291@1|root,COG3391@1|root,COG5184@1|root,COG5563@1|root,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5563@2|Bacteria,4PMAH@976|Bacteroidetes,1I2AU@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55802_2	1333523.L593_14450	1.06e-08	57.8	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,23WU7@183963|Halobacteria	183963|Halobacteria	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
k59_161770_1	43989.cce_4963	1.04e-190	540.0	COG3385@1|root,COG3385@2|Bacteria,1G3DG@1117|Cyanobacteria,3KJJ3@43988|Cyanothece	1117|Cyanobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_138135_1	298654.FraEuI1c_0084	5.18e-23	103.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4ESG4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_32432_1	443255.SCLAV_p1240	1.51e-45	162.0	COG1413@1|root,COG1413@2|Bacteria,2IDW3@201174|Actinobacteria	201174|Actinobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_85188_1	7668.SPU_007728-tr	3.4e-29	122.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,RVT_1
k59_161788_1	518766.Rmar_1441	1.32e-41	150.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_132098_1	6087.XP_004209882.1	7.77e-75	252.0	2CXPK@1|root,2RYWI@2759|Eukaryota,3A0FF@33154|Opisthokonta,3BPTP@33208|Metazoa	33208|Metazoa	-	-	-	-	2.1.1.43	ko:K11433	ko00310,map00310	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	DDE_3,HTH_Tnp_Tc3_2,Transposase_1
k59_179309_1	706587.Desti_5585	2.82e-05	45.1	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
k59_179309_2	880072.Desac_1037	9.15e-80	251.0	COG1304@1|root,COG2221@1|root,COG1304@2|Bacteria,COG2221@2|Bacteria	2|Bacteria	C	Nitrite and sulphite reductase 4Fe-4S	yahG	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1033	DUF1116,FMN_dh,Fer4,Glu_synthase
k59_126344_1	9305.ENSSHAP00000005200	1.53e-19	90.1	KOG1721@1|root,KOG1721@2759|Eukaryota,39W1Q@33154|Opisthokonta,3BK7X@33208|Metazoa,3CYZW@33213|Bilateria,488JP@7711|Chordata,497BJ@7742|Vertebrata,3JBIH@40674|Mammalia,4K7X6@9263|Metatheria	33208|Metazoa	S	piggyBac transposable element derived 1	PGBD1	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7,SCAN
k59_120462_1	1121451.DESAM_20087	2.78e-17	86.7	COG1271@1|root,COG1271@2|Bacteria,1R5SQ@1224|Proteobacteria,43BBG@68525|delta/epsilon subdivisions,2X6QP@28221|Deltaproteobacteria,2MH5E@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	oxidase subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2928_1	697281.Mahau_0354	8.55e-50	169.0	COG1044@1|root,COG1044@2|Bacteria,1UHYP@1239|Firmicutes,25E78@186801|Clostridia,42J5I@68295|Thermoanaerobacterales	186801|Clostridia	M	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
k59_26738_1	72664.XP_006405523.1	3.3e-260	712.0	28IP8@1|root,2QR09@2759|Eukaryota,37PUB@33090|Viridiplantae,3GEYD@35493|Streptophyta,3HX10@3699|Brassicales	35493|Streptophyta	C	Photosystem II (PSII) is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1 D2 (PsbA PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors	psbA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0010287,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	1.10.3.9	ko:K02703,ko:K20000	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko03016	-	-	-	Photo_RC
k59_26738_2	4572.TRIUR3_00083-P1	1.42e-236	665.0	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,3KWRZ@4447|Liliopsida,3IFBD@38820|Poales	35493|Streptophyta	J	Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_61580_1	880073.Calab_0214	4.56e-79	261.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_179310_1	1379698.RBG1_1C00001G0597	7.74e-65	217.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_179310_2	697281.Mahau_1416	6.28e-25	103.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,42FQD@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Class II aldolase adducin	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k59_90956_1	1122927.KB895420_gene4189	7.82e-18	86.7	COG1653@1|root,COG1653@2|Bacteria,1U4H4@1239|Firmicutes,4HBJP@91061|Bacilli,26TKK@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	malE	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k59_138177_1	400682.PAC_15705505	2e-87	283.0	28MXD@1|root,2QUFX@2759|Eukaryota,38TCJ@33154|Opisthokonta,3BIIF@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108643_1	4081.Solyc01g007630.2.1	2.52e-63	204.0	COG0090@1|root,KOG0438@2759|Eukaryota,37QJY@33090|Viridiplantae,3G9KA@35493|Streptophyta,44KYN@71274|asterids	35493|Streptophyta	J	Ribosomal Proteins L2, C-terminal domain	rpl2	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L23,Ribosomal_L2_C
k59_108643_2	29760.VIT_03s0038g02780.t01	1.77e-59	183.0	COG0089@1|root,2S1Z9@2759|Eukaryota,37VSJ@33090|Viridiplantae,3GJY5@35493|Streptophyta	35493|Streptophyta	J	ribosomal protein L23	rpl23	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_172953_2	1382306.JNIM01000001_gene466	2.85e-59	202.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_73327_1	1240350.AMZE01000064_gene3221	5.85e-64	220.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_102634_2	324925.Ppha_2533	1.16e-22	98.2	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_149936_1	1122185.N792_06010	6.25e-47	171.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1PTWJ@1224|Proteobacteria,1RZH5@1236|Gammaproteobacteria,1X55X@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,Peptidase_M1
k59_20077_1	1192034.CAP_7530	1.18e-77	247.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k59_61597_1	13037.EHJ78345	1.26e-114	362.0	KOG3105@1|root,KOG3105@2759|Eukaryota,38DQS@33154|Opisthokonta,3BGR7@33208|Metazoa,3D3JB@33213|Bilateria,426V1@6656|Arthropoda,3SXKE@50557|Insecta,44935@7088|Lepidoptera	33208|Metazoa	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_1,HTH_psq
k59_20086_1	1379698.RBG1_1C00001G0583	6.65e-33	132.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
k59_55885_1	379066.GAU_1710	9.46e-73	231.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_55885_2	1121931.AUHG01000010_gene349	1.05e-21	97.1	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_132158_1	1379698.RBG1_1C00001G1194	1.59e-20	98.2	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
k59_43881_1	648996.Theam_0361	5.93e-26	103.0	COG1136@1|root,COG1136@2|Bacteria,2G4P0@200783|Aquificae	200783|Aquificae	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_43881_2	755732.Fluta_2024	7.27e-06	53.9	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1HX67@117743|Flavobacteriia,2PAVH@246874|Cryomorphaceae	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
k59_2960_1	266265.Bxe_C0610	1.04e-15	78.2	COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2W6SY@28216|Betaproteobacteria,1KCJX@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_129522_1	643648.Slip_0989	8.61e-53	173.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,42JUT@68298|Syntrophomonadaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_129522_2	338963.Pcar_1919	1.47e-13	69.7	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_176495_1	632518.Calow_1187	4.98e-57	199.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42F5B@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_129525_1	1195246.AGRI_15866	1.54e-64	224.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,46458@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_29701_1	927658.AJUM01000037_gene2204	1.61e-25	110.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,2FNEV@200643|Bacteroidia,3XJGX@558415|Marinilabiliaceae	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k59_82473_2	1121090.KB894704_gene1560	2.26e-35	135.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZBCS@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	bfmBC	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_182251_1	714943.Mucpa_2935	1.88e-08	55.8	2ET37@1|root,33KMD@2|Bacteria,4NV8I@976|Bacteroidetes,1IYYH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182251_13	460265.Mnod_3592	8.45e-25	100.0	2DPAY@1|root,331AT@2|Bacteria,1N6ZM@1224|Proteobacteria,2UG3N@28211|Alphaproteobacteria,1JYB2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
k59_182251_14	1123508.JH636446_gene6362	5.16e-34	126.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_12023_1	441620.Mpop_0471	2.99e-23	101.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,1JQS3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_12023_2	1304888.ATWF01000002_gene420	1.97e-46	159.0	COG0681@1|root,COG0681@2|Bacteria,2GFCU@200930|Deferribacteres	200930|Deferribacteres	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
k59_47276_1	7897.ENSLACP00000005816	7.15e-51	176.0	2CYJA@1|root,2S4S7@2759|Eukaryota,3A62Z@33154|Opisthokonta,3BTAY@33208|Metazoa,3E403@33213|Bilateria,48M4T@7711|Chordata	33208|Metazoa	S	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	FLYWCH,MULE
k59_59039_1	1192034.CAP_1689	2.89e-88	275.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43957@68525|delta/epsilon subdivisions,2X4BI@28221|Deltaproteobacteria,2YYP6@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
k59_170576_1	394221.Mmar10_0329	2.09e-46	161.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,43X3M@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	COG1702 Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_141252_1	204669.Acid345_2181	1.33e-09	62.8	COG4365@1|root,COG4365@2|Bacteria,3Y4D6@57723|Acidobacteria,2JKER@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
k59_141252_2	1444712.BN1013_00561	9.89e-08	52.8	COG0598@1|root,COG0598@2|Bacteria,2JGHC@204428|Chlamydiae	204428|Chlamydiae	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_53171_1	926550.CLDAP_14630	2.11e-80	266.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi	200795|Chloroflexi	F	Carbamoyl-phosphate synthetase large chain domain protein	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_170579_1	7029.ACYPI54047-PA	3.24e-05	51.6	28HC0@1|root,2QPQD@2759|Eukaryota	7029.ACYPI54047-PA|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100127_1	886293.Sinac_7190	1.85e-34	137.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k59_158844_1	986075.CathTA2_2155	3.42e-82	248.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HAR6@91061|Bacilli	91061|Bacilli	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_129562_1	1379698.RBG1_1C00001G0340	4.86e-96	310.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
k59_76697_1	218284.CCDN010000001_gene579	1.14e-20	92.4	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,1ZERT@1386|Bacillus	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_94245_1	247490.KSU1_B0647	6.09e-24	99.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76705_1	483219.LILAB_14245	2.43e-22	96.3	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42URE@68525|delta/epsilon subdivisions,2WR5V@28221|Deltaproteobacteria,2YY8T@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_123753_1	316274.Haur_2141	4.12e-65	224.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
k59_59050_2	269799.Gmet_2013	9.38e-14	73.6	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,42VRI@68525|delta/epsilon subdivisions,2WRUV@28221|Deltaproteobacteria,43VFC@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_106100_1	1304878.AUGD01000001_gene346	4.38e-23	97.1	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria,3JZ2C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_158870_1	1463917.JODC01000007_gene7195	1.41e-17	88.6	COG4870@1|root,COG4870@2|Bacteria,2ICZT@201174|Actinobacteria	201174|Actinobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
k59_76719_1	1519464.HY22_05590	4.02e-48	178.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
k59_123773_1	1191523.MROS_0667	9.51e-13	73.6	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,Laminin_G_3,SLH,TonB_dep_Rec
k59_158885_1	998674.ATTE01000001_gene2863	8.04e-105	333.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,45ZY9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_106131_1	648996.Theam_0465	3.36e-48	168.0	COG4784@1|root,COG4784@2|Bacteria,2G5I7@200783|Aquificae	200783|Aquificae	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_135415_1	251221.35211458	8.93e-05	52.8	COG2374@1|root,COG2706@1|root,COG2374@2|Bacteria,COG2706@2|Bacteria,1GQSX@1117|Cyanobacteria	1117|Cyanobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TIG,VCBS
k59_29780_1	1123393.KB891331_gene2994	8.01e-11	64.7	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VMVD@28216|Betaproteobacteria,1KSQH@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_170634_1	1380763.BG53_02755	6.17e-17	85.1	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,26SV7@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_117769_1	243233.MCA1736	1.04e-20	92.8	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XDYK@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_123787_1	314271.RB2654_05547	6.72e-28	116.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_123787_2	754477.Q7C_2443	3.21e-39	139.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales	72273|Thiotrichales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_117771_1	203124.Tery_4229	4.21e-29	120.0	COG0840@1|root,COG1511@1|root,COG2770@1|root,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,1GQZG@1117|Cyanobacteria	1117|Cyanobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP
k59_111897_1	1385515.N791_00005	1.63e-07	52.4	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
k59_111897_2	1538644.KO02_18970	1.01e-31	125.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_129595_1	281687.CJA15137	5.22e-48	189.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3DKJZ@33213|Bilateria,40GWW@6231|Nematoda,1KZYW@119089|Chromadorea,412EV@6236|Rhabditida	33208|Metazoa	K	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_94289_1	518766.Rmar_2561	1.29e-58	198.0	COG1523@1|root,COG3291@1|root,COG1523@2|Bacteria,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1FJYC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_64953_2	1410653.JHVC01000013_gene3621	3.11e-14	73.6	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,36EKE@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_59077_1	1035191.HMPREF0185_02286	0.000101	50.1	COG1662@1|root,COG1662@2|Bacteria,1MV8R@1224|Proteobacteria,2TURN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM IS1 transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1,DDE_Tnp_IS240
k59_59658_1	106582.XP_004570865.1	4.19e-67	231.0	28PS4@1|root,2QWEM@2759|Eukaryota,39STS@33154|Opisthokonta,3BM2D@33208|Metazoa,3D4ZE@33213|Bilateria,48DF9@7711|Chordata,498UM@7742|Vertebrata	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_130105_3	403905.A7J284_9CAUD	5.12e-124	374.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae	10699|Siphoviridae	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_176939_1	443143.GM18_4224	3.18e-37	137.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,43STU@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_159312_1	1191523.MROS_0859	2.32e-131	400.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_118148_1	9541.XP_005547714.1	1.47e-44	170.0	COG2940@1|root,KOG1082@2759|Eukaryota,390I7@33154|Opisthokonta,3BG3F@33208|Metazoa,3CXSN@33213|Bilateria,4837X@7711|Chordata,490SN@7742|Vertebrata,3J9QM@40674|Mammalia,35NR1@314146|Euarchontoglires,4MF7F@9443|Primates,369A0@314294|Cercopithecoidea	33208|Metazoa	B	SET domain and mariner transposase fusion gene	SETMAR	GO:0000014,GO:0000075,GO:0000278,GO:0000726,GO:0000729,GO:0000737,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005730,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006282,GO:0006302,GO:0006303,GO:0006308,GO:0006325,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007093,GO:0007346,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008283,GO:0008757,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010452,GO:0010564,GO:0010604,GO:0010639,GO:0010911,GO:0010912,GO:0010948,GO:0015074,GO:0016043,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0018022,GO:0018024,GO:0018027,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0019899,GO:0022402,GO:0031297,GO:0031323,GO:0031325,GO:0031570,GO:0031974,GO:0031981,GO:0032259,GO:0032781,GO:0033043,GO:0033044,GO:0033554,GO:0034641,GO:0034645,GO:0034655,GO:0034968,GO:0035861,GO:0036211,GO:0042054,GO:0042800,GO:0042802,GO:0042803,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043462,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0044547,GO:0044774,GO:0045005,GO:0045739,GO:0045786,GO:0045787,GO:0045930,GO:0045935,GO:0046483,GO:0046700,GO:0046975,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051128,GO:0051129,GO:0051171,GO:0051173,GO:0051276,GO:0051336,GO:0051345,GO:0051568,GO:0051716,GO:0051726,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0071156,GO:0071157,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0090734,GO:0097159,GO:0097676,GO:0140096,GO:0140097,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1903047,GO:2000371,GO:2000373,GO:2000779,GO:2000781,GO:2001020,GO:2001022,GO:2001032,GO:2001034,GO:2001251	2.1.1.43	ko:K11433	ko00310,map00310	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	Pre-SET,SET,Transposase_1
k59_82958_1	880073.Calab_3407	1.75e-15	87.0	COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria	2|Bacteria	T	COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1
k59_47708_1	338966.Ppro_3603	1.59e-163	474.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2WJMT@28221|Deltaproteobacteria,43TB3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
k59_59478_1	1196083.SALWKB12_0515	6.18e-13	68.2	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,2KTXF@206351|Neisseriales	206351|Neisseriales	L	NUDIX domain	nudB	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
k59_77158_1	984262.SGRA_3891	2.82e-79	252.0	COG0286@1|root,COG0286@2|Bacteria,4NG0E@976|Bacteroidetes,1IQM3@117747|Sphingobacteriia	976|Bacteroidetes	V	COG0286 Type I restriction-modification system methyltransferase subunit	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_6673_1	1121013.P873_13790	1.97e-06	53.9	COG1680@1|root,COG1680@2|Bacteria,1R49D@1224|Proteobacteria,1S4AC@1236|Gammaproteobacteria,1X72E@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_65351_1	7668.SPU_005219-tr	2.49e-32	130.0	28S9B@1|root,2QYYT@2759|Eukaryota,39WZH@33154|Opisthokonta,3BHGG@33208|Metazoa,3E527@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4806
k59_36098_1	1121438.JNJA01000001_gene2128	8.26e-11	66.2	COG0348@1|root,COG0348@2|Bacteria,1MY5M@1224|Proteobacteria,42QNC@68525|delta/epsilon subdivisions,2WMUV@28221|Deltaproteobacteria,2MA8V@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	yccM-1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_5
k59_165423_1	351348.Maqu_4128	6.04e-114	343.0	COG2771@1|root,COG4584@1|root,COG2771@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,46A5W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
k59_129978_1	10224.XP_006823517.1	5.78e-12	71.2	COG3222@1|root,2R8AJ@2759|Eukaryota,3A2D9@33154|Opisthokonta,3BQE2@33208|Metazoa,3D80D@33213|Bilateria	33208|Metazoa	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2064,Glycos_transf_2
k59_65358_1	177437.HRM2_34570	9.66e-48	167.0	COG0477@1|root,COG2814@2|Bacteria,1R9V9@1224|Proteobacteria,42Q1C@68525|delta/epsilon subdivisions,2WK7P@28221|Deltaproteobacteria,2MMQA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_59491_1	1379698.RBG1_1C00001G0598	3.78e-80	246.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_65360_1	400682.PAC_15700319	2.91e-16	77.4	KOG1121@1|root,KOG1121@2759|Eukaryota	2759|Eukaryota	E	protein dimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_12584_1	1392489.JPOL01000002_gene2324	5.37e-49	181.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia,2XHZ8@283735|Leeuwenhoekiella	976|Bacteroidetes	L	DnaB-helicase binding domain of primase	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_77174_1	948565.AFFP02000001_gene995	1.18e-50	179.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1Y7T6@135625|Pasteurellales	135625|Pasteurellales	S	abc transporter atp-binding protein	Z012_08270	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_159359_1	7897.ENSLACP00000004258	3.22e-07	56.6	2B36B@1|root,2S0E9@2759|Eukaryota,3A1KW@33154|Opisthokonta,3BSTV@33208|Metazoa,3D7KR@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FLYWCH,MULE
k59_147546_1	935567.JAES01000004_gene16	2.8e-44	147.0	COG1695@1|root,COG1695@2|Bacteria,1NJSY@1224|Proteobacteria,1SG6R@1236|Gammaproteobacteria,1X6UG@135614|Xanthomonadales	135614|Xanthomonadales	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
k59_42023_1	523791.Kkor_1832	1.65e-19	91.7	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XIJ4@135619|Oceanospirillales	135619|Oceanospirillales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_65386_2	448385.sce6597	1.35e-20	89.7	2E5WH@1|root,330KI@2|Bacteria,1QAVR@1224|Proteobacteria,435BU@68525|delta/epsilon subdivisions,2WZPC@28221|Deltaproteobacteria,2Z2GK@29|Myxococcales	28221|Deltaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_65386_3	859657.RPSI07_mp0251	1.67e-22	92.8	COG3293@1|root,COG3293@2|Bacteria,1N13W@1224|Proteobacteria,2VUET@28216|Betaproteobacteria,1K8V1@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k59_65386_4	196164.23494819	7.67e-27	106.0	COG3293@1|root,COG3293@2|Bacteria,2IKID@201174|Actinobacteria,22NN5@1653|Corynebacteriaceae	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k59_832_1	8364.ENSXETP00000061713	9.15e-21	97.4	28KB6@1|root,2QSS1@2759|Eukaryota,39XKI@33154|Opisthokonta,3BPWM@33208|Metazoa,3D7K7@33213|Bilateria,48K8W@7711|Chordata,49H7W@7742|Vertebrata	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	THAP
k59_106545_1	386456.JQKN01000004_gene176	3.82e-10	63.5	COG0642@1|root,COG0784@1|root,arCOG02333@2157|Archaea,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,HisKA_4TM,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_165456_1	1353529.M899_1599	8.37e-13	73.9	COG3591@1|root,COG3591@2|Bacteria,1NP6U@1224|Proteobacteria,42ZKY@68525|delta/epsilon subdivisions,2WUS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_106547_2	1121405.dsmv_2695	7.24e-07	54.3	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_130005_2	3760.EMJ16090	1.93e-09	59.3	KOG1776@1|root,KOG1776@2759|Eukaryota,37NYR@33090|Viridiplantae,3G7MS@35493|Streptophyta,4JJE2@91835|fabids	35493|Streptophyta	T	Auxin transport protein	-	GO:0000003,GO:0000902,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005911,GO:0006810,GO:0007275,GO:0008150,GO:0009314,GO:0009416,GO:0009506,GO:0009605,GO:0009607,GO:0009620,GO:0009628,GO:0009639,GO:0009640,GO:0009653,GO:0009719,GO:0009725,GO:0009733,GO:0009791,GO:0009826,GO:0009914,GO:0009926,GO:0009987,GO:0010015,GO:0010016,GO:0010033,GO:0010101,GO:0010102,GO:0010229,GO:0010311,GO:0010817,GO:0016020,GO:0016043,GO:0016049,GO:0022414,GO:0022622,GO:0030054,GO:0032501,GO:0032502,GO:0032989,GO:0040007,GO:0042221,GO:0043207,GO:0044424,GO:0044444,GO:0044464,GO:0048281,GO:0048364,GO:0048367,GO:0048527,GO:0048528,GO:0048589,GO:0048608,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055044,GO:0060560,GO:0060918,GO:0061458,GO:0065007,GO:0065008,GO:0071840,GO:0090567,GO:0090696,GO:0090697,GO:0090698,GO:0099402,GO:1905392,GO:1905393	2.3.2.27	ko:K10691	ko05165,ko05203,map05165,map05203	-	-	-	ko00000,ko00001,ko01000,ko04121	-	-	-	E3_UbLigase_R4,ZZ
k59_83026_1	926562.Oweho_2795	8.8e-18	90.5	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,CARDB,Calx-beta,Cleaved_Adhesin,DUF4465,Glyco_tran_WbsX,fn3
k59_47784_1	6183.Smp_195160.1	1.7e-22	102.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_177030_1	880526.KE386488_gene1366	8.44e-34	129.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,2FRGC@200643|Bacteroidia	976|Bacteroidetes	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_147581_2	29760.VIT_00s0396g00050.t01	1.26e-191	537.0	28P22@1|root,2QVNI@2759|Eukaryota,37SGH@33090|Viridiplantae,3GFX8@35493|Streptophyta	35493|Streptophyta	S	ribosomal protein S4	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
k59_118243_1	6326.BUX.s00333.49	1.32e-15	79.0	COG2940@1|root,KOG4443@2759|Eukaryota,38F1W@33154|Opisthokonta,3B98N@33208|Metazoa,3CXIX@33213|Bilateria,40C3K@6231|Nematoda,1KUEH@119089|Chromadorea	33208|Metazoa	K	PHD zinc finger	KMT2D	GO:0000003,GO:0000981,GO:0001067,GO:0001555,GO:0001701,GO:0002682,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006325,GO:0006342,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008284,GO:0008757,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0009994,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0016043,GO:0016049,GO:0016278,GO:0016279,GO:0016458,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023056,GO:0030154,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0034708,GO:0034968,GO:0035097,GO:0036211,GO:0040007,GO:0040028,GO:0040029,GO:0042054,GO:0042127,GO:0042800,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043627,GO:0043933,GO:0044085,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044666,GO:0044703,GO:0045595,GO:0045637,GO:0045652,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048468,GO:0048477,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048583,GO:0048584,GO:0048588,GO:0048589,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051704,GO:0060255,GO:0061062,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0140096,GO:0140110,GO:1901363,GO:1901564,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1904837,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2001141	2.1.1.43	ko:K09187,ko:K09188	ko00310,ko04934,map00310,map04934	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03000,ko03036	-	-	-	FYRC,FYRN,PHD,SET,zf-HC5HC2H,zf-HC5HC2H_2
k59_100677_1	1173025.GEI7407_2283	2.62e-09	59.7	COG0612@1|root,COG0612@2|Bacteria,1G1CD@1117|Cyanobacteria,1H75R@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the peptidase M16 family	pqqE	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_112372_1	521098.Aaci_1182	9.1e-09	59.7	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	ste14	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k59_118246_1	1499967.BAYZ01000095_gene4239	5.29e-53	193.0	COG1100@1|root,COG2319@1|root,COG1100@2|Bacteria,COG2319@2|Bacteria,2NREY@2323|unclassified Bacteria	2|Bacteria	M	Anaphase-promoting complex subunit 4 WD40 domain	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,DUF4365,FGE-sulfatase,Metallophos,OmpA,PD40,Ras,TIR_2,WD40
k59_30234_1	525904.Tter_1070	1.91e-23	96.3	2CI1U@1|root,32X07@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_30234_2	204669.Acid345_2223	1.34e-06	52.0	COG0629@1|root,COG0629@2|Bacteria,3Y4D2@57723|Acidobacteria,2JJ18@204432|Acidobacteriia	204432|Acidobacteriia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_42055_1	1191523.MROS_1336	1.38e-73	248.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_83040_1	1125863.JAFN01000001_gene2111	4.85e-107	315.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_83040_2	765914.ThisiDRAFT_2349	1.85e-19	87.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1WXKZ@135613|Chromatiales	135613|Chromatiales	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_153414_1	246195.DNO_1304	1.96e-05	47.8	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
k59_124813_2	378806.STAUR_4552	4.35e-12	67.4	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2YZBI@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_42624_2	589865.DaAHT2_0509	3.77e-30	116.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,2MI0E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_83615_1	1122132.AQYH01000005_gene474	7.64e-72	236.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,4B9NZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_77778_1	1120977.JHUX01000003_gene1897	9.92e-52	177.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,3NISF@468|Moraxellaceae	1236|Gammaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_77778_2	91464.S7335_2104	0.000282	42.7	COG0740@1|root,COG0740@2|Bacteria,1FZVH@1117|Cyanobacteria,1GZ0E@1129|Synechococcus	1117|Cyanobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_173182_1	1047013.AQSP01000108_gene2058	2.16e-09	64.7	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_67885_1	1188256.BASI01000001_gene523	5.38e-09	56.6	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,2UBXI@28211|Alphaproteobacteria,3FEE7@34008|Rhodovulum	28211|Alphaproteobacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
k59_73498_1	1379698.RBG1_1C00001G1218	9.79e-13	73.6	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
k59_132287_1	395961.Cyan7425_3850	8.85e-95	285.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,3KFW2@43988|Cyanothece	1117|Cyanobacteria	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_114161_1	7668.SPU_017677-tr	6.02e-17	90.1	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3C1BS@33208|Metazoa,3DJ0V@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_179524_1	6087.XP_002157831.2	6.62e-26	107.0	28HC0@1|root,2QPQD@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_184899_1	717606.PaecuDRAFT_4078	1.12e-33	120.0	COG0838@1|root,COG0838@2|Bacteria,1V6P3@1239|Firmicutes,4HIFX@91061|Bacilli,26XI4@186822|Paenibacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_3170_1	1304284.L21TH_0306	1.86e-18	92.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,25CA6@186801|Clostridia,36WS4@31979|Clostridiaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_3170_2	929556.Solca_1054	2.74e-30	117.0	COG4912@1|root,COG4912@2|Bacteria,4NHAJ@976|Bacteroidetes	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_144093_1	1273538.G159_16915	3.68e-08	56.6	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,4HDPA@91061|Bacilli,26FNP@186818|Planococcaceae	91061|Bacilli	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
k59_144093_2	398512.JQKC01000019_gene3515	2.43e-20	91.3	COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,24B8G@186801|Clostridia,3WMNP@541000|Ruminococcaceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_97593_1	525282.HMPREF0391_10625	1.55e-05	47.8	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,22I4W@1570339|Peptoniphilaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_3177_1	1297581.H919_00825	4.01e-06	51.6	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4HBSK@91061|Bacilli,21WB6@150247|Anoxybacillus	91061|Bacilli	C	Phosphate acetyl/butaryl transferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	iYO844.BSU24090	PTA_PTB
k59_3177_2	1292035.H476_0053	7.67e-28	112.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,25QTD@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
k59_73525_1	1342301.JASD01000008_gene1467	6.78e-13	73.6	COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,2TT5H@28211|Alphaproteobacteria,3ZWQ5@60136|Sulfitobacter	28211|Alphaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
k59_144095_1	6087.XP_004210371.1	2.05e-23	98.2	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa	33208|Metazoa	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_126538_1	316274.Haur_3718	1.65e-48	169.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,2G5PG@200795|Chloroflexi,3751N@32061|Chloroflexia	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K18926	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338,M00715	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.3.30	-	-	CBS,MFS_1,PALP
k59_67920_1	1173020.Cha6605_0050	3.19e-06	51.2	COG1253@1|root,COG1253@2|Bacteria,1G1AQ@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_67920_2	1121405.dsmv_0430	2.03e-50	171.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_9130_1	986075.CathTA2_1039	3.51e-79	246.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bfmBAB	-	1.2.4.4	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU24040	Transket_pyr,Transketolase_C
k59_102843_1	7029.ACYPI39645-PA	2.53e-07	57.0	2CQ46@1|root,2R3SC@2759|Eukaryota,39VF0@33154|Opisthokonta,3BMCX@33208|Metazoa,3D3BX@33213|Bilateria,41VVT@6656|Arthropoda,3SKN1@50557|Insecta	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_179568_1	311424.DhcVS_852	1.28e-119	350.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,34CJX@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
k59_20287_1	1499967.BAYZ01000060_gene6006	1.18e-59	194.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,2NPJ5@2323|unclassified Bacteria	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
k59_38605_1	880073.Calab_0146	7.57e-09	61.6	COG0382@1|root,COG0382@2|Bacteria,2NRJ9@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.39,2.5.1.62	ko:K03179,ko:K04040	ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110	M00117	R05000,R05615,R06284,R09067,R11514,R11517	RC00020,RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_73539_1	1111069.TCCBUS3UF1_11960	6.53e-05	50.8	COG3383@1|root,COG3383@2|Bacteria,1WJDD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_44072_1	1437448.AZRT01000049_gene147	4.12e-127	390.0	COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage terminase-like protein large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
k59_44072_2	1028801.RG1141_CH01610	8.97e-116	353.0	COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,4BDDS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
k59_44072_4	1115653.S5M7Q8_9CAUD	1.66e-13	74.7	4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPUI@28883|Caudovirales,4QNGU@10744|Podoviridae	10744|Podoviridae	S	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44072_5	1121448.DGI_2053	9.36e-112	346.0	COG4653@1|root,COG4653@2|Bacteria,1MXMN@1224|Proteobacteria,42UKA@68525|delta/epsilon subdivisions,2WQZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
k59_44072_6	1028801.RG1141_CH01640	6.23e-17	80.9	2E6Z0@1|root,331I7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44072_16	1245469.S58_39640	1.3e-06	55.8	COG2242@1|root,COG2242@2|Bacteria,1QW6F@1224|Proteobacteria,2TWPP@28211|Alphaproteobacteria,3JV9N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_91125_1	7668.SPU_027821-tr	5.48e-78	265.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_179578_1	886882.PPSC2_p0165	5.71e-21	96.7	COG0739@1|root,COG0739@2|Bacteria,1UKQQ@1239|Firmicutes,4ITX0@91061|Bacilli	91061|Bacilli	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_3211_1	292459.STH1184	4.15e-05	50.8	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1VNAP@1239|Firmicutes,24W68@186801|Clostridia	186801|Clostridia	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
k59_120742_1	1224164.B843_07440	8.74e-41	153.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,22JNI@1653|Corynebacteriaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_79611_1	861299.J421_3737	5.24e-43	155.0	COG0644@1|root,COG0644@2|Bacteria,1ZV85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Lycopene cyclase protein	-	-	1.3.1.111,1.3.1.83,1.3.99.38	ko:K10960,ko:K21401	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
k59_85373_1	1304874.JAFY01000005_gene1107	1.35e-62	207.0	COG0162@1|root,COG0162@2|Bacteria,3T9YV@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_120747_1	926569.ANT_16170	9.61e-124	365.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_97622_1	445973.CLOBAR_00519	4.17e-06	50.4	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9149_1	706587.Desti_0293	7.27e-22	89.4	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MS9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_50577_1	945713.IALB_2784	2.78e-91	295.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
k59_27898_1	1379698.RBG1_1C00001G0618	5.99e-07	52.8	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
k59_180707_1	1321781.HMPREF1985_00887	4.14e-10	61.2	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4H2CA@909932|Negativicutes	909932|Negativicutes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_180707_3	1562701.BBOF01000014_gene588	0.000817	43.1	COG3027@1|root,COG3027@2|Bacteria,1N2HS@1224|Proteobacteria,2VV1T@28216|Betaproteobacteria,1K8Q1@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_38985_1	1173264.KI913949_gene1641	9.62e-07	48.9	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k59_38985_2	933262.AXAM01000204_gene1274	1.3e-42	144.0	COG1895@1|root,COG1895@2|Bacteria,1Q7Y6@1224|Proteobacteria,433AB@68525|delta/epsilon subdivisions,2WYB2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
k59_15579_1	644282.Deba_1281	2.99e-72	233.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_85737_1	1267003.KB911373_gene775	1.89e-06	53.5	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k59_109269_1	1125863.JAFN01000001_gene2574	1.33e-55	184.0	COG0704@1|root,COG0704@2|Bacteria,1NRGK@1224|Proteobacteria	1224|Proteobacteria	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
k59_44482_1	555088.DealDRAFT_0664	1.62e-33	129.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,42KCA@68298|Syntrophomonadaceae	186801|Clostridia	S	FAD binding domain	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_32888_1	459349.CLOAM1724	1.27e-75	246.0	COG2866@1|root,COG2866@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K06987,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,Peptidase_M14
k59_127028_2	530564.Psta_0587	6.61e-38	136.0	2BGX2@1|root,32AX0@2|Bacteria,2J32R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68324_1	398512.JQKC01000009_gene568	6.52e-75	256.0	COG1020@1|root,COG1020@2|Bacteria,1V12Q@1239|Firmicutes,24ER3@186801|Clostridia,3WNBS@541000|Ruminococcaceae	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,B12-binding,Condensation,PP-binding,QueC,Radical_SAM
k59_15600_1	765911.Thivi_0478	2.4e-39	140.0	COG3039@1|root,COG3039@2|Bacteria,1N88K@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
k59_91486_1	62928.azo3169	1.6e-42	153.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,2KUQC@206389|Rhodocyclales	206389|Rhodocyclales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_114483_1	555079.Toce_1868	2.13e-39	146.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,42FAH@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Peptidase M20	abgA	-	-	ko:K01436,ko:K12940	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_85740_1	400682.PAC_15700877	4e-22	104.0	KOG1121@1|root,KOG1121@2759|Eukaryota	2759|Eukaryota	E	protein dimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_68339_1	502025.Hoch_2554	2.79e-07	54.7	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2YXI4@29|Myxococcales	68525|delta/epsilon subdivisions	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_168297_1	1306947.ARQD01000001_gene600	3.68e-41	147.0	COG1373@1|root,COG1373@2|Bacteria,2NP9F@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
k59_80019_1	880073.Calab_0884	2.42e-89	288.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_150575_1	404380.Gbem_3723	3.9e-50	168.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WJEC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	JM	PFAM Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k59_44508_1	555088.DealDRAFT_0490	2.39e-40	146.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42JZZ@68298|Syntrophomonadaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
k59_168308_1	883.DvMF_2016	7.47e-07	52.4	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2WQ35@28221|Deltaproteobacteria,2MGD6@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_168308_2	642492.Clole_2440	1.75e-12	70.5	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
k59_114531_1	693661.Arcve_0410	8.11e-35	133.0	COG3635@1|root,arCOG01696@2157|Archaea,2XTE8@28890|Euryarchaeota,2461V@183980|Archaeoglobi	183980|Archaeoglobi	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
k59_162411_1	266265.Bxe_B2926	1.03e-15	81.3	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,1K0GR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_62129_1	358681.BBR47_54960	8.46e-32	125.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,274FZ@186822|Paenibacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, middle domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_80027_1	1379698.RBG1_1C00001G0265	1.78e-13	71.2	COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria	2|Bacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338,ko:K03610	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400,ko04812	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_39017_1	1121403.AUCV01000043_gene65	3.11e-15	80.5	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1R9PF@1224|Proteobacteria,42RF1@68525|delta/epsilon subdivisions,2WNZ0@28221|Deltaproteobacteria,2MPY7@213118|Desulfobacterales	28221|Deltaproteobacteria	PT	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Na_H_Exchanger,Usp
k59_56582_2	621372.ACIH01000276_gene845	1.16e-11	71.6	COG3385@1|root,COG3385@2|Bacteria,1TPH7@1239|Firmicutes,4IRJE@91061|Bacilli,276TJ@186822|Paenibacillaceae	91061|Bacilli	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_20773_1	400682.PAC_15708465	1.84e-60	224.0	29YJV@1|root,2RXU5@2759|Eukaryota,3A0FB@33154|Opisthokonta,3BPYT@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144645_1	880073.Calab_0992	2.27e-58	191.0	COG2006@1|root,COG2006@2|Bacteria,2NQF7@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_62135_2	945713.IALB_2792	8.5e-69	234.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Omp_AT
k59_20779_1	7668.SPU_008007-tr	2.12e-22	101.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_121161_1	1121405.dsmv_3556	1.43e-108	329.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MJ1N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_114568_1	981384.AEYW01000014_gene131	1.77e-11	70.5	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,4NC5D@97050|Ruegeria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_156054_1	6334.EFV56018	3.38e-24	106.0	2CNDJ@1|root,2QVFB@2759|Eukaryota,39MN8@33154|Opisthokonta,3CP8H@33208|Metazoa,3E5D2@33213|Bilateria	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_180096_1	102107.XP_008236536.1	3.73e-169	481.0	COG0356@1|root,KOG4665@2759|Eukaryota,37J5M@33090|Viridiplantae,3GEF0@35493|Streptophyta,4JSKT@91835|fabids	35493|Streptophyta	C	ATP synthase A chain	atp6-1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	ko:K02126	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko03029	3.A.2.1	-	-	ATP-synt_A
k59_98611_2	1201288.M900_A0222	2.15e-22	97.1	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM sodium alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_50474_6	3659.XP_004153565.1	4.5e-95	284.0	2A7BJ@1|root,2RYDW@2759|Eukaryota,37U5M@33090|Viridiplantae,3GHQH@35493|Streptophyta	35493|Streptophyta	S	RIBOSOMAL protein	rps1	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
k59_50474_10	3988.XP_002534772.1	9.09e-36	123.0	2CVN9@1|root,2S4GY@2759|Eukaryota,37WBG@33090|Viridiplantae,3GKIW@35493|Streptophyta,4JUZW@91835|fabids	35493|Streptophyta	P	ATP synthase subunit C	ATP9	GO:0000276,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02128	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_C
k59_73199_1	7029.ACYPI085965-PA	1.04e-49	182.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,42BZI@6656|Arthropoda,3SVZS@50557|Insecta,3EDZB@33342|Paraneoptera	33208|Metazoa	-	-	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_8793_1	5147.XP_003342391.1	2.06e-24	106.0	2D7IC@1|root,2T6DH@2759|Eukaryota,390CD@33154|Opisthokonta,3PZXZ@4751|Fungi,3R5PC@4890|Ascomycota	4751|Fungi	L	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
k59_38279_1	1265505.ATUG01000001_gene4104	8.24e-39	139.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42RQX@68525|delta/epsilon subdivisions,2WNM1@28221|Deltaproteobacteria,2MJTS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_161720_1	1087481.AGFX01000047_gene2101	4.29e-08	60.5	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
k59_102524_1	56780.SYN_00471	1.05e-62	203.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2MQCV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_90852_1	771875.Ferpe_1130	4.13e-39	146.0	COG1253@1|root,COG1253@2|Bacteria,2GCB4@200918|Thermotogae	200918|Thermotogae	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_2830_1	59374.Fisuc_1614	4.34e-14	77.4	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria	2|Bacteria	T	Histidine kinase	icfG	-	3.1.3.3	ko:K07315,ko:K16928	-	M00582	-	-	ko00000,ko00002,ko01000,ko02000,ko03021	3.A.1.33	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
k59_3354_1	1121033.AUCF01000010_gene4416	1.01e-09	65.9	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2JQW4@204441|Rhodospirillales	204441|Rhodospirillales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,PAS_8,Response_reg
k59_126747_1	7029.ACYPI065517-PA	2.21e-61	208.0	2D1YK@1|root,2SJTH@2759|Eukaryota,3AIHT@33154|Opisthokonta,3BY39@33208|Metazoa,3DFEE@33213|Bilateria,4226M@6656|Arthropoda,3SQKM@50557|Insecta,3EDI1@33342|Paraneoptera	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_179728_1	998088.B565_3315	2.58e-17	81.6	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1Y3JF@135624|Aeromonadales	135624|Aeromonadales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_179728_2	1379698.RBG1_1C00001G1138	1.55e-30	123.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_132511_1	529884.Rhola_00002140	4.75e-37	139.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4FM8H@85023|Microbacteriaceae	201174|Actinobacteria	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_3358_1	1408473.JHXO01000011_gene3210	2.75e-33	132.0	COG0421@1|root,COG0421@2|Bacteria,4NTHI@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114308_1	1235457.C404_13360	1.42e-10	60.8	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2VHU1@28216|Betaproteobacteria,1K0E4@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
k59_114308_2	575540.Isop_2692	1.45e-81	259.0	COG0624@1|root,COG0624@2|Bacteria,2IXPJ@203682|Planctomycetes	203682|Planctomycetes	E	ArgE DapE Acy1 family protein	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_185112_1	1379698.RBG1_1C00001G1208	2.26e-36	129.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	mshB	-	-	ko:K02456,ko:K02650,ko:K10924,ko:K10925	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin,T2SSG
k59_73754_1	448385.sce8319	3.67e-19	84.7	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2X2EG@28221|Deltaproteobacteria,2Z20T@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_73754_2	208444.JNYY01000012_gene7839	2.62e-13	70.5	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind,LRR_5,SLH,Tyrosinase,VWA,VWA_2
k59_126756_1	929562.Emtol_2275	2.73e-124	363.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,47K0T@768503|Cytophagia	976|Bacteroidetes	S	alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_9302_1	1209989.TepiRe1_0317	2.37e-20	95.1	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,42EYT@68295|Thermoanaerobacterales	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_15299_1	1095769.CAHF01000022_gene46	3.23e-28	105.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,2W271@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_126762_1	7029.ACYPI43907-PA	1.12e-63	226.0	2CN9K@1|root,2QUP8@2759|Eukaryota,3A12D@33154|Opisthokonta,3BQGV@33208|Metazoa,3D6IK@33213|Bilateria,421YE@6656|Arthropoda,3SQ8D@50557|Insecta,3EED2@33342|Paraneoptera	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_68114_1	646529.Desaci_3158	9.26e-38	136.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia,261FY@186807|Peptococcaceae	186801|Clostridia	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
k59_68114_2	1286106.MPL1_03508	0.000379	42.7	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,462GF@72273|Thiotrichales	72273|Thiotrichales	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_168056_1	7897.ENSLACP00000001098	1.65e-35	139.0	2CNDJ@1|root,2QVFB@2759|Eukaryota,39MN8@33154|Opisthokonta,3CP8H@33208|Metazoa,3E5D2@33213|Bilateria,48RT0@7711|Chordata,49N6G@7742|Vertebrata	33208|Metazoa	S	Transposase IS4	-	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0016604,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0070013	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_20489_1	7668.SPU_000029-tr	1.53e-23	105.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A7X5@33154|Opisthokonta,3C05U@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1891,Exo_endo_phos,RVT_1
k59_132550_1	933262.AXAM01000078_gene1601	1.32e-66	221.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2MKAY@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_20497_1	7668.SPU_006692-tr	1.07e-27	119.0	2D15D@1|root,2SGRS@2759|Eukaryota,3ACYM@33154|Opisthokonta,3BWPV@33208|Metazoa,3DD17@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3402_1	1121342.AUCO01000004_gene514	2.35e-37	143.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,36DQF@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_120916_2	981383.AEWH01000044_gene3135	5.45e-25	107.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_132560_1	7029.ACYPI40720-PA	1.18e-07	58.5	28PS4@1|root,2QWEM@2759|Eukaryota,39STS@33154|Opisthokonta,3BM2D@33208|Metazoa,3D4ZE@33213|Bilateria,420QK@6656|Arthropoda,3SNGI@50557|Insecta	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7,Tnp_zf-ribbon_2
k59_85568_1	439235.Dalk_0736	1.78e-55	189.0	COG2204@1|root,COG2204@2|Bacteria,1MVWX@1224|Proteobacteria,42MIB@68525|delta/epsilon subdivisions,2WJQK@28221|Deltaproteobacteria,2MHU2@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_91296_1	1122137.AQXF01000006_gene817	7.09e-05	47.4	COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,2TUIR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_49948_1	1192034.CAP_0012	3.5e-72	233.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2YU6J@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_9012_1	235985.BBPN01000017_gene5648	2.82e-05	52.8	COG0026@1|root,COG0026@2|Bacteria,2I5KF@201174|Actinobacteria	201174|Actinobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
k59_9012_2	177437.HRM2_10500	2.67e-08	56.2	COG5653@1|root,COG5653@2|Bacteria,1MV00@1224|Proteobacteria,42PW5@68525|delta/epsilon subdivisions,2WKPE@28221|Deltaproteobacteria,2MIEF@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_38459_1	767817.Desgi_0928	2.25e-44	160.0	COG5557@1|root,COG5557@2|Bacteria,1TSZC@1239|Firmicutes,24BX8@186801|Clostridia,260DH@186807|Peptococcaceae	186801|Clostridia	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_43980_1	414996.IL38_13330	1.13e-89	280.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,407N3@622450|Actinopolysporales	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_43980_2	1382359.JIAL01000001_gene2270	7.82e-27	105.0	COG4221@1|root,COG4221@2|Bacteria,3Y426@57723|Acidobacteria,2JHVQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_184830_2	479434.Sthe_3156	9.39e-140	404.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,27XHP@189775|Thermomicrobia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818,ko:K11707	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_184830_3	383372.Rcas_1723	5.42e-132	380.0	COG1121@1|root,COG1121@2|Bacteria,2G5WQ@200795|Chloroflexi,374U1@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K11710	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
k59_73399_1	1550091.JROE01000001_gene4121	2.2e-22	90.5	2ETMH@1|root,33M58@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73399_2	856793.MICA_276	4.75e-80	258.0	COG0610@1|root,COG0610@2|Bacteria	2|Bacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	Z012_07420	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII,Z1
k59_120613_1	7668.SPU_025383-tr	1.7e-41	164.0	COG2801@1|root,KOG0017@2759|Eukaryota,38GIZ@33154|Opisthokonta,3BMWT@33208|Metazoa,3CTK8@33213|Bilateria	33208|Metazoa	L	genomic stop codons	-	-	-	-	-	-	-	-	-	-	-	-	Gag_p30,RNase_H,RVP,RVT_1,rve,zf-CCHC
k59_167769_1	552811.Dehly_1379	1.26e-19	92.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_13
k59_97500_1	7668.SPU_027820-tr	1.36e-32	140.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_102781_1	1089553.Tph_c23180	8.94e-102	325.0	COG1372@1|root,COG4626@1|root,COG1372@2|Bacteria,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,42EYP@68295|Thermoanaerobacterales	186801|Clostridia	L	Phage Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
k59_91044_1	1265507.KB899636_gene2552	1.05e-39	145.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1Y3PQ@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_97503_1	1210908.HSB1_24800	2.39e-51	175.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XYKQ@28890|Euryarchaeota,23W9T@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_126446_1	219305.MCAG_05245	2.12e-99	298.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DAXK@85008|Micromonosporales	201174|Actinobacteria	EK	Cystathionine beta-synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_144032_1	1280676.AUJO01000011_gene951	4.98e-10	64.7	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,4BWQ3@830|Butyrivibrio	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_97512_2	7739.XP_002597526.1	9.44e-38	140.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,48QAV@7711|Chordata	33208|Metazoa	S	Ribonuclease H protein	-	-	2.3.1.15,2.4.2.29	ko:K13506,ko:K15407	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R03789,R09380,R10209	RC00004,RC00039,RC00041,RC00063	ko00000,ko00001,ko00002,ko01000,ko01004,ko03016	-	-	-	Exo_endo_phos_2,RVT_1
k59_126455_1	643648.Slip_1875	1.93e-07	53.5	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,42JPF@68298|Syntrophomonadaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_79476_1	509191.AEDB02000067_gene832	8.09e-69	233.0	COG4447@1|root,COG4733@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,1TQB3@1239|Firmicutes,247VI@186801|Clostridia,3WSI4@541000|Ruminococcaceae	186801|Clostridia	G	Cellulose binding domain	-	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Glyco_hydro_48,Glyco_hydro_9
k59_15038_1	7668.SPU_008679-tr	5.92e-20	94.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_97524_1	1122947.FR7_4370	5.58e-19	87.8	COG1595@1|root,COG1595@2|Bacteria,1TSCX@1239|Firmicutes	1239|Firmicutes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	NTF2,Sigma70_r2,Sigma70_r4_2
k59_20168_1	5334.XP_003033315.1	0.000771	48.9	COG2801@1|root,KOG0017@2759|Eukaryota,3AKRK@33154|Opisthokonta,3PE9Z@4751|Fungi,3VCKX@5204|Basidiomycota,229U8@155619|Agaricomycetes,3W79U@5338|Agaricales	4751|Fungi	L	to polyprotein	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_32495_4	29760.VIT_00s1739g00010.t01	3.93e-78	237.0	2CDXT@1|root,2S1NU@2759|Eukaryota,37VRF@33090|Viridiplantae,3GJAF@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144051_1	7719.XP_004227204.1	2.39e-20	94.4	28IIP@1|root,2QQVP@2759|Eukaryota,39TA7@33154|Opisthokonta,3CNWS@33208|Metazoa,3D3DK@33213|Bilateria,48D3U@7711|Chordata	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_132253_1	102107.XP_008224000.1	8.49e-211	646.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta,4JREA@91835|fabids	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	ycf1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	-	-	-	-	-	-	-	-	-	Ycf1
k59_132253_2	59689.Al_scaffold_0009_187	1.1e-37	128.0	COG0184@1|root,KOG2815@2759|Eukaryota,37W6V@33090|Viridiplantae,3GKIP@35493|Streptophyta	35493|Streptophyta	J	30S ribosomal protein S15	rps15	GO:0000312,GO:0000313,GO:0000314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0009507,GO:0009532,GO:0009536,GO:0009547,GO:0009570,GO:0015935,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_132253_3	59689.scaffold_900034.1	7.93e-270	740.0	COG0649@1|root,KOG2870@2759|Eukaryota,37KKG@33090|Viridiplantae,3GDNP@35493|Streptophyta,3I15P@3699|Brassicales	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhH	GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0015979,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0019866,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0055035,GO:0055114,GO:0070469,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05572,ko:K05579	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_49kDa,NADHdh
k59_132253_4	981085.XP_010087977.1	1.2e-98	290.0	COG1005@1|root,KOG4770@2759|Eukaryota,37RCJ@33090|Viridiplantae,3GDCI@35493|Streptophyta,4JUHV@91835|fabids	35493|Streptophyta	C	NADH dehydrogenase	ndhA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0019866,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0055114,GO:0070469,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05572	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	NADHdh
k59_132253_6	3702.ATCG01100.1	3.95e-100	300.0	COG1005@1|root,KOG4770@2759|Eukaryota,37RCJ@33090|Viridiplantae,3GDCI@35493|Streptophyta	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0019866,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0055114,GO:0070469,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05572	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	NADHdh
k59_132253_7	3983.cassava4.1_021875m	2.87e-97	286.0	COG1143@1|root,KOG3256@2759|Eukaryota,37YQF@33090|Viridiplantae,3GCUY@35493|Streptophyta,4JSC0@91835|fabids	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhI	GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0055114	1.6.5.3	ko:K05580	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
k59_132253_8	3983.cassava4.1_023131m	2.37e-93	276.0	COG0839@1|root,2QQHR@2759|Eukaryota,37N23@33090|Viridiplantae,3GCEY@35493|Streptophyta,4JS5P@91835|fabids	35493|Streptophyta	C	Belongs to the complex I subunit 6 family	ndhG	GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0044237	1.6.5.3	ko:K05578	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q3
k59_132253_9	4113.PGSC0003DMT400029490	1.39e-55	174.0	KOG4669@1|root,KOG4669@2759|Eukaryota,37V63@33090|Viridiplantae,3GJK7@35493|Streptophyta,44TJB@71274|asterids	35493|Streptophyta	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008137,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042180,GO:0042181,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050136,GO:0051186,GO:0051188,GO:0055035,GO:0055114,GO:0071704,GO:0098796,GO:1901576,GO:1901661,GO:1901663,GO:1902494	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
k59_132253_10	3075.A0A023HHU3	3.35e-36	124.0	COG1145@1|root,2S26M@2759|Eukaryota,37VAY@33090|Viridiplantae,34IB8@3041|Chlorophyta	3041|Chlorophyta	C	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn	psaC	-	-	ko:K02691	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Fer4
k59_132253_11	3827.XP_004516946.1	1.15e-296	821.0	COG1008@1|root,KOG4845@2759|Eukaryota,37QQT@33090|Viridiplantae,3G7MJ@35493|Streptophyta,4JSGR@91835|fabids	35493|Streptophyta	C	NAD(P)H-quinone oxidoreductase chain 4	ndhD	-	1.6.5.3	ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M
k59_132253_12	29760.VIT_00s0246g00170.t01	3.84e-145	416.0	COG0755@1|root,2QU0T@2759|Eukaryota,37NBU@33090|Viridiplantae,3GH1G@35493|Streptophyta	35493|Streptophyta	O	Cytochrome c biogenesis protein CcsA	ccsA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0008152,GO:0009536,GO:0015886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:1901678	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_44061_1	682795.AciX8_1361	1.68e-27	107.0	29YNM@1|root,30KI8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_97552_1	4081.Solyc03g063940.1.1	6.41e-45	166.0	COG2801@1|root,KOG0017@2759|Eukaryota,37VVP@33090|Viridiplantae,3GJYB@35493|Streptophyta	35493|Streptophyta	L	gag-polypeptide of LTR copia-type	-	-	-	-	-	-	-	-	-	-	-	-	Retrotran_gag_2
k59_15063_1	1379698.RBG1_1C00001G1846	8.34e-57	199.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_167799_1	1077285.AGDG01000034_gene4634	9.79e-25	105.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,2FNFB@200643|Bacteroidia,4AKKB@815|Bacteroidaceae	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_167799_2	861299.J421_3393	1.53e-36	132.0	COG0777@1|root,COG0777@2|Bacteria,1ZSSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_126485_1	944547.ABLL_2631	2.22e-74	236.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria	1224|Proteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_114145_1	1121459.AQXE01000008_gene785	1.1e-21	97.8	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WPR9@28221|Deltaproteobacteria,2M7TV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_150085_1	760568.Desku_2155	4.49e-79	249.0	COG3829@1|root,COG3829@2|Bacteria,1V0EF@1239|Firmicutes,24DXA@186801|Clostridia	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_38529_1	880073.Calab_3211	3.17e-88	277.0	COG1027@1|root,COG1027@2|Bacteria,2NNUK@2323|unclassified Bacteria	2|Bacteria	E	Fumarase C C-terminus	aspA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222	FumaraseC_C,Lyase_1
k59_9071_2	1223410.KN050846_gene1906	1.22e-76	251.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1HX3E@117743|Flavobacteriia	976|Bacteroidetes	O	peptidase family M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
k59_155465_1	580340.Tlie_0077	3.5e-76	241.0	COG1157@1|root,COG1157@2|Bacteria,3TA6Z@508458|Synergistetes	508458|Synergistetes	NU	TIGRFAM ATPase, FliI YscN family	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_132275_6	272563.CD630_09360	9.04e-22	92.0	COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,24P18@186801|Clostridia	186801|Clostridia	L	Endodeoxyribonuclease RusA	rusA	-	-	-	-	-	-	-	-	-	-	-	RusA
k59_155466_1	1167006.UWK_03444	5.46e-22	100.0	COG2197@1|root,COG3852@1|root,COG2197@2|Bacteria,COG3852@2|Bacteria,1R2HI@1224|Proteobacteria,42ZPI@68525|delta/epsilon subdivisions,2WUU1@28221|Deltaproteobacteria,2MPPT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,Response_reg
k59_85335_1	8128.ENSONIP00000023376	7.69e-58	197.0	2CMVD@1|root,2QS6T@2759|Eukaryota,38ITZ@33154|Opisthokonta,3BGFP@33208|Metazoa,3D162@33213|Bilateria,482X8@7711|Chordata,493ZA@7742|Vertebrata,4A52W@7898|Actinopterygii	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,GTF2I
k59_46630_2	517417.Cpar_0694	9.92e-28	112.0	COG0845@1|root,COG0845@2|Bacteria,1FDCQ@1090|Chlorobi	1090|Chlorobi	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k59_58524_1	335543.Sfum_2600	1.7e-18	84.7	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_140470_1	682795.AciX8_0772	4.62e-17	84.3	COG0793@1|root,COG3577@1|root,COG0793@2|Bacteria,COG3577@2|Bacteria,3Y8S0@57723|Acidobacteria	57723|Acidobacteria	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
k59_46633_1	177437.HRM2_09300	9.46e-47	167.0	COG0041@1|root,COG0151@1|root,COG0041@2|Bacteria,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
k59_34949_2	1521187.JPIM01000094_gene1031	2.28e-36	132.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi,375IT@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_11400_2	485915.Dret_2002	7.15e-146	424.0	COG3464@1|root,COG3464@2|Bacteria,1R4DH@1224|Proteobacteria,43AQ4@68525|delta/epsilon subdivisions,2X63W@28221|Deltaproteobacteria,2MGXP@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
k59_22813_1	1191523.MROS_2370	5.8e-46	164.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_105063_2	1236542.BALM01000026_gene1939	5.24e-08	55.1	COG1018@1|root,COG3369@1|root,COG3592@1|root,COG1018@2|Bacteria,COG3369@2|Bacteria,COG3592@2|Bacteria,1RF85@1224|Proteobacteria,1S4MQ@1236|Gammaproteobacteria,2QCMK@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175591_1	1379698.RBG1_1C00001G1579	3.27e-18	79.7	COG0098@1|root,COG0098@2|Bacteria,2NPGN@2323|unclassified Bacteria	2|Bacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_175591_2	596323.HMPREF0554_0299	5.14e-26	101.0	COG0256@1|root,COG0256@2|Bacteria,37ADG@32066|Fusobacteria	32066|Fusobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_175591_3	699218.HMPREF0889_0883	1.44e-67	211.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4H3Z2@909932|Negativicutes	909932|Negativicutes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_87897_1	7668.SPU_006447-tr	4.47e-114	344.0	KOG4585@1|root,KOG4585@2759|Eukaryota,39THK@33154|Opisthokonta,3BGF1@33208|Metazoa,3D09T@33213|Bilateria	33208|Metazoa	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
k59_134776_2	1304275.C41B8_19126	3.5e-54	178.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_123158_1	6087.XP_004210595.1	1.37e-22	98.6	2E589@1|root,2SC2F@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82187_1	247490.KSU1_D0400	8.16e-09	62.8	COG2204@1|root,COG2204@2|Bacteria	247490.KSU1_D0400|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5734_2	1379698.RBG1_1C00001G0884	2.33e-35	136.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
k59_58555_1	1379698.RBG1_1C00001G1724	1.62e-49	170.0	COG0845@1|root,COG0845@2|Bacteria,2NR7K@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_64200_1	1280680.AUJU01000030_gene3638	1.41e-13	73.2	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TT52@1239|Firmicutes,249A9@186801|Clostridia,4BZKF@830|Butyrivibrio	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
k59_64200_2	1121396.KB893054_gene2403	3.54e-42	154.0	COG1055@1|root,COG1055@2|Bacteria,1QUC0@1224|Proteobacteria,43BR6@68525|delta/epsilon subdivisions,2WJVM@28221|Deltaproteobacteria,2MIF3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM sodium sulfate symporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp
k59_22844_2	439235.Dalk_4509	2.7e-33	124.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,434AT@68525|delta/epsilon subdivisions,2X9GM@28221|Deltaproteobacteria,2MNQ4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_111325_1	1191523.MROS_0324	2.87e-24	95.1	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup_1	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_76017_1	7217.FBpp0123329	1.74e-35	147.0	KOG1121@1|root,KOG1121@2759|Eukaryota,396MR@33154|Opisthokonta,3CB0A@33208|Metazoa,3DS8R@33213|Bilateria,4284I@6656|Arthropoda,3SSQH@50557|Insecta,45A9V@7147|Diptera,45YZ4@7214|Drosophilidae	33208|Metazoa	L	hAT family C-terminal dimerisation region	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_76020_1	329726.AM1_2164	1.73e-48	175.0	COG1100@1|root,COG2319@1|root,COG4916@1|root,COG1100@2|Bacteria,COG2319@2|Bacteria,COG4916@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_105119_2	1268635.Loa_01625	4.89e-12	63.2	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1JEIN@118969|Legionellales	118969|Legionellales	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k59_93653_1	448385.sce6651	6.72e-63	206.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,42Z4V@68525|delta/epsilon subdivisions,2WU31@28221|Deltaproteobacteria,2Z2U7@29|Myxococcales	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_35015_1	880073.Calab_3168	0.000133	51.2	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	-
k59_181983_2	981085.XP_010100012.1	8.29e-169	472.0	COG0356@1|root,KOG4665@2759|Eukaryota,37MBD@33090|Viridiplantae,3GH9B@35493|Streptophyta,4JDXB@91835|fabids	35493|Streptophyta	C	it plays a direct role in the translocation of protons across the membrane	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009579,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098807,GO:0099131,GO:0099132,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_181983_3	13333.ERN02618	2.99e-135	426.0	COG0052@1|root,COG0356@1|root,KOG0832@2759|Eukaryota,KOG4665@2759|Eukaryota,38964@33090|Viridiplantae,3GY32@35493|Streptophyta	35493|Streptophyta	J	RNA polymerase Rpb1, domain 5	rpoC2	-	2.7.7.6	ko:K02108,ko:K03046	ko00190,ko00195,ko00230,ko00240,ko01100,ko03020,map00190,map00195,map00230,map00240,map01100,map03020	M00157,M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko00194,ko01000,ko03021,ko03110,ko03400	3.A.2.1	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,Ribosomal_S2
k59_181983_4	4572.TRIUR3_00079-P1	0.0	2237.0	COG0086@1|root,2QPYA@2759|Eukaryota,37HSD@33090|Viridiplantae,3GDVE@35493|Streptophyta,3KV60@4447|Liliopsida,3I5C8@38820|Poales	35493|Streptophyta	K	DNA-directed RNA polymerase	rpoC2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_181983_5	59689.scaffold_201045.1	3.66e-284	827.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,3I0YM@3699|Brassicales	35493|Streptophyta	K	rna polymerase	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_181983_6	29730.Gorai.005G167700.1	1.27e-100	308.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta	35493|Streptophyta	K	rna polymerase	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_181983_7	3702.ATCG00190.1	0.0	1960.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,3I0YM@3699|Brassicales	35493|Streptophyta	K	rna polymerase	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_175636_1	344747.PM8797T_05260	5.82e-23	95.9	COG0344@1|root,COG0344@2|Bacteria,2J0DJ@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	DUF4149,G3P_acyltransf
k59_93668_1	316067.Geob_3374	3.83e-54	187.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k59_29307_1	1254432.SCE1572_23510	3.72e-20	85.1	COG2919@1|root,COG2919@2|Bacteria,1NM5U@1224|Proteobacteria,42X2K@68525|delta/epsilon subdivisions,2WSPM@28221|Deltaproteobacteria,2YW2R@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k59_123189_1	316056.RPC_1791	1.97e-08	60.8	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2U3P9@28211|Alphaproteobacteria,3JRA5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_146759_1	867903.ThesuDRAFT_01803	1.61e-27	117.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
k59_51841_1	880072.Desac_0069	5e-44	163.0	COG2864@1|root,COG2864@2|Bacteria,1N5K7@1224|Proteobacteria,42U9M@68525|delta/epsilon subdivisions,2WQ6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_76069_2	234267.Acid_7670	1.68e-19	91.3	COG0115@1|root,COG0115@2|Bacteria,3Y6HY@57723|Acidobacteria	57723|Acidobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_87941_2	1123242.JH636435_gene1400	7.04e-11	65.5	COG1070@1|root,COG1070@2|Bacteria,2IY9E@203682|Planctomycetes	203682|Planctomycetes	G	MutL protein	-	-	-	-	-	-	-	-	-	-	-	-	MutL
k59_64248_1	517418.Ctha_0317	2.03e-78	263.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_175647_1	6238.CBG27381	1.98e-44	160.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_76093_1	118161.KB235922_gene2455	4.35e-70	213.0	2D6H4@1|root,336JE@2|Bacteria,1GA3G@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76093_2	118161.KB235922_gene2456	1.43e-97	298.0	2C69V@1|root,2Z9DY@2|Bacteria,1G4DI@1117|Cyanobacteria	1117|Cyanobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_29346_1	1297742.A176_07526	6.05e-20	95.9	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WNZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_97931_1	6326.BUX.s00036.28	2.55e-34	131.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_144463_1	1159488.SEQMU2_05290	1.24e-10	70.9	COG5545@1|root,COG5545@2|Bacteria,1V7Z0@1239|Firmicutes,4IU5X@91061|Bacilli,4H1NW@90964|Staphylococcaceae	91061|Bacilli	S	Primase C terminal 1 (PriCT-1)	-	-	-	-	-	-	-	-	-	-	-	-	PriCT_1
k59_144463_2	1095750.HMPREF9970_1021	2.51e-44	163.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia	186801|Clostridia	L	DNA polymerase	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A
k59_168192_1	555779.Dthio_PD3372	4.96e-24	92.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,42U82@68525|delta/epsilon subdivisions,2WQQY@28221|Deltaproteobacteria,2MGN3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
k59_109208_1	1442599.JAAN01000035_gene644	0.000178	45.1	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1X3ST@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrE	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_109208_2	1223521.BBJX01000005_gene1851	2.41e-34	134.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAY8@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_79899_1	563192.HMPREF0179_00273	2.16e-35	134.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
k59_15452_1	1392487.JIAD01000001_gene332	2.53e-26	109.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_9352_1	1151122.AQYD01000004_gene2679	1.82e-13	75.1	2EXVQ@1|root,33R4U@2|Bacteria,2IDZ0@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
k59_168207_1	431943.CKL_0439	1.49e-93	289.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36EK3@31979|Clostridiaceae	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_97954_1	8090.ENSORLP00000003777	7.27e-11	63.5	2E5JP@1|root,2SCCX@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2
k59_121039_1	1307761.L21SP2_2933	2.1e-76	254.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,2J5QV@203691|Spirochaetes	203691|Spirochaetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_27265_1	1232410.KI421412_gene308	0.000233	50.4	COG0823@1|root,COG3303@1|root,COG5492@1|root,COG0823@2|Bacteria,COG3303@2|Bacteria,COG5492@2|Bacteria,1MZ1W@1224|Proteobacteria,43CT4@68525|delta/epsilon subdivisions,2X80N@28221|Deltaproteobacteria,43VYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27265_2	1191523.MROS_1186	1.24e-35	135.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
k59_3541_1	693977.Deipr_1018	5.25e-07	53.1	2AZWC@1|root,31S5X@2|Bacteria,1WIKZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
k59_3541_2	1340493.JNIF01000003_gene4283	1.12e-07	53.5	COG0790@1|root,COG0810@1|root,COG0790@2|Bacteria,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	infB	-	-	ko:K02519,ko:K03832,ko:K07126	-	-	-	-	ko00000,ko02000,ko03012,ko03029	2.C.1.1	-	-	CarbopepD_reg_2,Gram_pos_anchor,HtaA,Sel1,TonB_C,YSIRK_signal,YXWGXW
k59_173508_1	4096.XP_009787759.1	2.04e-120	374.0	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae,3GG2K@35493|Streptophyta,44UC5@71274|asterids	35493|Streptophyta	L	Mitochondrial protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve,zf-CCHC
k59_121044_1	1379270.AUXF01000002_gene1564	7.74e-53	196.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_179935_1	1047013.AQSP01000140_gene2536	6.02e-32	127.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_168225_1	945713.IALB_1993	1.5e-35	132.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_168225_2	880073.Calab_0619	4.19e-05	45.4	COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria	2|Bacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1
k59_144494_2	398720.MED217_13976	1.36e-17	82.4	2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,1I2KM@117743|Flavobacteriia,2XJD9@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_138519_1	3847.GLYMA12G29860.2	3.03e-29	113.0	2CKHQ@1|root,2S5E8@2759|Eukaryota,37WKE@33090|Viridiplantae,3GKNN@35493|Streptophyta	35493|Streptophyta	S	BEST Arabidopsis thaliana protein match is Mitovirus RNA-dependent RNA polymerase (TAIR	-	-	-	-	-	-	-	-	-	-	-	-	Mitovir_RNA_pol
k59_150483_1	243090.RB9488	1.14e-47	171.0	COG2855@1|root,COG2855@2|Bacteria,2IX2B@203682|Planctomycetes	203682|Planctomycetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_121052_1	1214065.BAGV01000100_gene2159	0.00027	48.5	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1S11E@1236|Gammaproteobacteria,283I1@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	N	Flagellar hook-associated protein 2 N-terminus	fliD	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_126960_1	1121428.DESHY_110011___1	2.48e-13	68.6	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_79934_1	41431.PCC8801_2966	4.33e-56	178.0	2D6H4@1|root,336JE@2|Bacteria,1GA3G@1117|Cyanobacteria,3KIVS@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79934_2	43989.cce_5205	2.76e-40	145.0	COG3385@1|root,COG3385@2|Bacteria,1G35A@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_79934_3	43989.cce_5205	6.87e-106	314.0	COG3385@1|root,COG3385@2|Bacteria,1G35A@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_3568_1	7029.ACYPI063934-PA	1.62e-38	141.0	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa,3DKI7@33213|Bilateria,422A5@6656|Arthropoda,3SQP0@50557|Insecta	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_85710_1	158190.SpiGrapes_0858	2.77e-26	108.0	COG3579@1|root,COG3579@2|Bacteria,2J5YK@203691|Spirochaetes	203691|Spirochaetes	E	Peptidase C1-like family	-	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
k59_85710_2	1340493.JNIF01000003_gene1466	4.68e-05	46.6	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	yihX	GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.10,3.1.3.104,3.8.1.2	ko:K01560,ko:K07025,ko:K20866,ko:K21063	ko00010,ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00010,map00361,map00625,map00740,map01100,map01110,map01120	M00125	R00947,R05287,R07280	RC00017,RC00078,RC00697	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
k59_68285_1	880073.Calab_2195	4.58e-17	86.3	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
k59_56463_1	391612.CY0110_12912	1.66e-162	472.0	COG5421@1|root,COG5421@2|Bacteria,1G3YW@1117|Cyanobacteria,3KJGF@43988|Cyanothece	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_9393_1	269799.Gmet_3478	2.01e-31	130.0	COG2202@1|root,COG2770@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,43UFI@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains Cache_1, HAMP, PAS, PAS	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1
k59_103151_2	1379698.RBG1_1C00001G1592	5.84e-46	149.0	COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_103151_3	941449.dsx2_2540	3.04e-51	170.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2M8B7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_38944_1	444158.MmarC6_0171	1.91e-64	217.0	COG4231@1|root,arCOG01609@2157|Archaea,2XUNR@28890|Euryarchaeota,23QNM@183939|Methanococci	183939|Methanococci	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_38944_2	316067.Geob_2795	2.51e-10	59.3	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k59_85726_1	1192034.CAP_5375	4.1e-69	232.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2YU54@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_132684_1	259536.Psyc_1530	4.7e-25	108.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,3NJ00@468|Moraxellaceae	1236|Gammaproteobacteria	M	zinc metalloprotease	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_56486_1	330084.JNYZ01000001_gene3196	5.92e-29	116.0	COG3118@1|root,COG3118@2|Bacteria,2I35R@201174|Actinobacteria	201174|Actinobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
k59_168241_1	8049.ENSGMOP00000009375	4.94e-105	330.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,487FB@7711|Chordata,491IP@7742|Vertebrata,4A56D@7898|Actinopterygii	33208|Metazoa	S	kiaa1586	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_15555_1	438753.AZC_2887	6.67e-72	241.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,3EYWG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_50072_1	6183.Smp_049150.1	9.31e-11	62.8	COG1448@1|root,KOG1412@2759|Eukaryota,39W2P@33154|Opisthokonta,3BE99@33208|Metazoa,3CZIY@33213|Bilateria	33208|Metazoa	E	Aspartate aminotransferase	GOT1	GO:0000323,GO:0003254,GO:0003674,GO:0003824,GO:0004069,GO:0004609,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005764,GO:0005773,GO:0005777,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006082,GO:0006094,GO:0006103,GO:0006106,GO:0006107,GO:0006114,GO:0006520,GO:0006531,GO:0006532,GO:0006533,GO:0006536,GO:0006537,GO:0006538,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009068,GO:0009084,GO:0009605,GO:0009612,GO:0009628,GO:0009719,GO:0009725,GO:0009743,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010646,GO:0010647,GO:0010712,GO:0010713,GO:0014070,GO:0016051,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016831,GO:0017015,GO:0019222,GO:0019318,GO:0019319,GO:0019400,GO:0019401,GO:0019550,GO:0019551,GO:0019725,GO:0019751,GO:0019752,GO:0023051,GO:0023052,GO:0023056,GO:0030003,GO:0030154,GO:0030424,GO:0030511,GO:0031406,GO:0031960,GO:0031974,GO:0031981,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032965,GO:0032966,GO:0033267,GO:0033993,GO:0034637,GO:0035902,GO:0036094,GO:0042221,GO:0042391,GO:0042579,GO:0042592,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043648,GO:0043649,GO:0043650,GO:0043679,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044281,GO:0044282,GO:0044283,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046165,GO:0046173,GO:0046364,GO:0046394,GO:0046395,GO:0046686,GO:0047801,GO:0048518,GO:0048519,GO:0048522,GO:0048545,GO:0048583,GO:0048584,GO:0048869,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051186,GO:0051384,GO:0051480,GO:0051481,GO:0051716,GO:0051881,GO:0051900,GO:0051902,GO:0055065,GO:0055074,GO:0055080,GO:0055081,GO:0055082,GO:0055088,GO:0055089,GO:0060290,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071214,GO:0071260,GO:0071310,GO:0071375,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0072503,GO:0072507,GO:0090092,GO:0090100,GO:0090287,GO:0097458,GO:0098771,GO:0098793,GO:0104004,GO:0120025,GO:0120038,GO:0150034,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901615,GO:1901617,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903844,GO:1903846,GO:1904180,GO:1990267	2.6.1.1	ko:K14454	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00710,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00710,map00950,map00960,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00170,M00171	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007,ko04131,ko04147	-	-	-	Aminotran_1_2
k59_114431_1	3656.XP_008460615.1	5.73e-124	397.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta,4JM10@91835|fabids	35493|Streptophyta	H	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Chromo,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_91469_1	1144275.COCOR_02810	3.46e-124	361.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,43475@68525|delta/epsilon subdivisions,2X27R@28221|Deltaproteobacteria,2YXCB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_33687_1	525373.HMPREF0766_11873	6.73e-34	131.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_56970_1	7897.ENSLACP00000001466	1.09e-37	144.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria,48QHZ@7711|Chordata,497ZU@7742|Vertebrata	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_156352_1	1379698.RBG1_1C00001G0056	3.84e-70	219.0	COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_156352_2	913865.DOT_0288	2.07e-07	54.3	COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,25ZY1@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_162825_1	1321778.HMPREF1982_01071	1.17e-30	124.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_39359_1	177437.HRM2_17170	3.24e-39	144.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2MIEV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_39361_1	880073.Calab_2120	1.23e-61	215.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_44929_1	595593.JREV01000033_gene3379	1.31e-11	68.9	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,1W7R5@1268|Micrococcaceae	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_44929_2	999141.GME_03742	2.01e-10	62.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1XH8C@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_62499_1	1273103.NM10_00824	3.3e-37	135.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4H4UZ@909932|Negativicutes	909932|Negativicutes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_180432_1	1121406.JAEX01000009_gene2653	4.03e-34	121.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria,2MBWV@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_103570_1	945713.IALB_1809	3.05e-86	264.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571,ko:K03497	-	-	-	-	ko00000,ko01000,ko02048,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc,RE_Eco29kI
k59_103570_2	1185652.USDA257_c48560	6.37e-34	134.0	COG3613@1|root,COG3613@2|Bacteria,1PPD1@1224|Proteobacteria,2V472@28211|Alphaproteobacteria,4BIZ5@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80427_2	742818.HMPREF9451_00701	1.4e-130	382.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CUJP@84998|Coriobacteriia	84998|Coriobacteriia	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_121515_1	880073.Calab_0310	1.23e-148	432.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
k59_62531_2	1379698.RBG1_1C00001G0347	3.82e-19	86.3	COG1657@1|root,COG1657@2|Bacteria,2NP7R@2323|unclassified Bacteria	2|Bacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159,Prenyltrans
k59_74418_1	1122603.ATVI01000006_gene440	1.62e-42	160.0	COG1387@1|root,COG1387@2|Bacteria,1R4SE@1224|Proteobacteria,1T1NC@1236|Gammaproteobacteria,1X8P6@135614|Xanthomonadales	135614|Xanthomonadales	E	Histidinol phosphatase and related hydrolases of the PHP family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109693_1	96561.Dole_0366	7.15e-70	214.0	2E5WH@1|root,330KI@2|Bacteria	2|Bacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_68791_2	1541065.JRFE01000014_gene1350	4.82e-12	68.6	28M84@1|root,2ZAMA@2|Bacteria,1G3CX@1117|Cyanobacteria,3VJH1@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62537_1	1123242.JH636436_gene501	7.57e-65	210.0	COG0330@1|root,COG0330@2|Bacteria,2IY12@203682|Planctomycetes	203682|Planctomycetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_86194_1	867845.KI911784_gene2767	8.49e-49	166.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
k59_33385_1	1121377.KB906401_gene3506	9.42e-35	127.0	COG0039@1|root,COG0039@2|Bacteria,1WJHY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_16009_1	439235.Dalk_3678	1.31e-36	137.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2MIY7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_74437_1	1121948.AUAC01000008_gene828	4.56e-23	93.2	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria,43Y00@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
k59_91927_1	266117.Rxyl_2488	1.84e-19	92.8	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
k59_39431_1	1033734.CAET01000024_gene1197	8.53e-16	80.5	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,4HA7V@91061|Bacilli,1ZFYD@1386|Bacillus	91061|Bacilli	S	Prolyl oligopeptidase family	yfhR3	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_180478_1	653733.Selin_2484	7.53e-49	166.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_180478_2	192952.MM_3343	1.91e-72	221.0	COG3335@1|root,arCOG02127@2157|Archaea	2157|Archaea	L	Homeodomain-like domain	-	-	-	ko:K07494,ko:K07499	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
k59_98503_1	1379698.RBG1_1C00001G1053	2.09e-142	413.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_33397_2	1304885.AUEY01000054_gene171	8.57e-23	96.3	COG0632@1|root,COG0632@2|Bacteria,1Q5HB@1224|Proteobacteria,42R4Y@68525|delta/epsilon subdivisions,2WMRB@28221|Deltaproteobacteria,2MJPI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_N
k59_39438_1	941449.dsx2_3393	5.12e-26	107.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria,2M8JK@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_121537_1	1379698.RBG1_1C00001G1089	7.72e-28	113.0	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5,PAS,PAS_3,PAS_9,Response_reg
k59_121537_2	290318.Cvib_1460	8.93e-08	55.1	COG1994@1|root,COG1994@2|Bacteria,1FD7V@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_103612_1	6500.XP_005110414.1	2.11e-79	263.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3E41I@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_27746_1	7029.ACYPI34794-PA	1.78e-57	197.0	28PS4@1|root,2QWEM@2759|Eukaryota,39STS@33154|Opisthokonta,3BM2D@33208|Metazoa,3D4ZE@33213|Bilateria,420QK@6656|Arthropoda,3SNGI@50557|Insecta	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7,Tnp_zf-ribbon_2
k59_68818_1	144197.XP_008300009.1	3.03e-05	49.3	2E9HG@1|root,2SFVC@2759|Eukaryota,3ACQV@33154|Opisthokonta,3BWFP@33208|Metazoa,3DC6N@33213|Bilateria,48HFF@7711|Chordata,49FVI@7742|Vertebrata,4A5QD@7898|Actinopterygii	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4806
k59_168777_1	1382315.JPOI01000001_gene1129	4.85e-112	335.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HD4F@91061|Bacilli,1WGDJ@129337|Geobacillus	91061|Bacilli	E	DegT/DnrJ/EryC1/StrS aminotransferase family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_33416_1	1125863.JAFN01000001_gene2903	2.16e-98	295.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_39971_2	3988.XP_002535856.1	1.02e-13	66.6	2EAFF@1|root,2SGPE@2759|Eukaryota,37XN0@33090|Viridiplantae,3GMKE@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_39971_4	40149.OMERI06G00830.1	1.53e-08	55.5	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta,3M2Z2@4447|Liliopsida,3ID3P@38820|Poales	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	nad7	-	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k59_39971_5	3712.Bo01107s020.1	5.59e-12	65.9	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase (Ubiquinone) iron-sulfur protein	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa
k59_92590_1	1121930.AQXG01000013_gene3302	4.08e-08	54.7	COG4796@1|root,COG4796@2|Bacteria,4NGRG@976|Bacteroidetes,1IRCC@117747|Sphingobacteriia	976|Bacteroidetes	U	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin,Secretin_N
k59_92590_2	1379698.RBG1_1C00001G0236	1.8e-23	95.9	COG2259@1|root,COG2259@2|Bacteria,2NRSH@2323|unclassified Bacteria	2|Bacteria	S	PFAM Methylamine utilisation protein MauE	mauE	-	-	-	-	-	-	-	-	-	-	-	MauE
k59_91555_1	443144.GM21_1427	1.12e-107	324.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria	1224|Proteobacteria	P	Ammonium transporter	-	-	-	ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11.4	-	-	Ammonium_transp
k59_39050_1	1499967.BAYZ01000078_gene971	2.9e-18	84.7	COG2199@1|root,COG3706@2|Bacteria,2NPCY@2323|unclassified Bacteria	2|Bacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
k59_103289_1	1444309.JAQG01000019_gene582	2.98e-07	60.5	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HBXI@91061|Bacilli,274YI@186822|Paenibacillaceae	91061|Bacilli	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
k59_121211_1	3656.XP_008463403.1	1.29e-28	118.0	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta,4JN0G@91835|fabids	35493|Streptophyta	L	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3,rve
k59_114603_1	319225.Plut_1677	1.53e-49	186.0	COG1196@1|root,COG1196@2|Bacteria,1FDPC@1090|Chlorobi	1090|Chlorobi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_27389_1	3847.GLYMA13G04690.2	2.59e-73	221.0	COG0838@1|root,KOG4662@2759|Eukaryota,37UN0@33090|Viridiplantae,3GISB@35493|Streptophyta,4JUVD@91835|fabids	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008137,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
k59_27389_2	4155.Migut.D01428.1.p	1.84e-138	396.0	COG0377@1|root,KOG1687@2759|Eukaryota,37QTD@33090|Viridiplantae,3GHED@35493|Streptophyta,44RGU@71274|asterids	35493|Streptophyta	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	ndhK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3	ko:K05582	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q6
k59_27389_3	4155.Migut.D01427.1.p	2.4e-115	330.0	COG0852@1|root,KOG1713@2759|Eukaryota,37QGD@33090|Viridiplantae,3GGF5@35493|Streptophyta,44PBS@71274|asterids	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	ndhJ	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K05581	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_30kDa
k59_27389_5	4155.Migut.D01426.1.p	1.89e-124	356.0	COG0522@1|root,KOG3301@2759|Eukaryota,37TGK@33090|Viridiplantae,3G7BN@35493|Streptophyta,44PVZ@71274|asterids	35493|Streptophyta	J	Ribosomal protein S4/S9 N-terminal domain	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_27389_6	72664.XP_006404497.1	9.27e-49	157.0	COG0457@1|root,KOG1124@2759|Eukaryota,37TZH@33090|Viridiplantae,3GKZ9@35493|Streptophyta	35493|Streptophyta	S	Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits	ycf3	-	-	-	-	-	-	-	-	-	-	-	TPR_1
k59_27389_7	50452.W0USV0	0.0	1524.0	28JJ8@1|root,2QRYE@2759|Eukaryota,37RH7@33090|Viridiplantae,3GCW8@35493|Streptophyta,3I0SM@3699|Brassicales	35493|Streptophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0009987,GO:0010287,GO:0015979,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02689	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k59_27389_8	4155.Migut.J01360.1.p	0.0	1504.0	28JJ8@1|root,2QRYE@2759|Eukaryota,37QY5@33090|Viridiplantae,3GH5Y@35493|Streptophyta,44Q5F@71274|asterids	35493|Streptophyta	C	Photosystem I psaA/psaB protein	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016168,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k59_27389_9	4155.Migut.J01359.1.p	1.25e-60	187.0	COG0199@1|root,KOG1741@2759|Eukaryota,37VQM@33090|Viridiplantae,3GJZT@35493|Streptophyta	35493|Streptophyta	J	Binds 16S rRNA, required for the assembly of 30S particles	rps14	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_168414_1	1117647.M5M_10885	3.32e-68	224.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,1J5GX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	alsS	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_39080_1	1123288.SOV_2c08330	6.79e-92	281.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,4H2FM@909932|Negativicutes	909932|Negativicutes	E	Glutamate formiminotransferase	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
k59_114621_1	485915.Dret_0454	4.71e-87	285.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1NTJT@1224|Proteobacteria,42NK8@68525|delta/epsilon subdivisions,2WIM0@28221|Deltaproteobacteria,2M8SV@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
k59_85826_1	1379698.RBG1_1C00001G0777	1.11e-81	268.0	COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
k59_50245_1	1122137.AQXF01000005_gene1189	3.01e-05	51.6	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2TQSU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_98220_1	6412.HelroP172394	3.79e-58	204.0	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa,3E5DG@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98225_1	614083.AWQR01000023_gene157	1.22e-54	183.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,4ABTQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_39119_1	1232410.KI421424_gene1673	1.43e-56	197.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43RZ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_185482_1	1123234.AUKI01000023_gene2024	1.14e-09	65.1	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_44618_1	765911.Thivi_3566	5.06e-48	162.0	28JYD@1|root,2Z9NN@2|Bacteria,1MV9T@1224|Proteobacteria,1S18H@1236|Gammaproteobacteria,1WWSD@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156116_1	126957.SMAR012277-PA	5.11e-14	75.9	2FAI9@1|root,2TBR2@2759|Eukaryota,3971J@33154|Opisthokonta,3CBCP@33208|Metazoa,3DSMV@33213|Bilateria,423UW@6656|Arthropoda	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_185489_1	536233.CLO_3152	7.48e-09	60.5	COG1309@1|root,COG1309@2|Bacteria,1V9BD@1239|Firmicutes,24G2B@186801|Clostridia,36IJG@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_68486_1	397287.C807_04007	2.37e-29	123.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,27JNW@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
k59_74120_1	96561.Dole_1980	5.77e-47	162.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,2MIPV@213118|Desulfobacterales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_121280_1	1121445.ATUZ01000011_gene871	3.63e-15	77.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_44636_1	7070.TC003734-PA	1.54e-34	140.0	2CY95@1|root,2S2X3@2759|Eukaryota,3A4AR@33154|Opisthokonta,3BRVC@33208|Metazoa,3D8TC@33213|Bilateria,422C0@6656|Arthropoda,3SR3A@50557|Insecta	33208|Metazoa	S	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
k59_132838_1	1379698.RBG1_1C00001G0777	5.64e-39	145.0	COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
k59_150710_1	7668.SPU_016030-tr	2.45e-52	188.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3BPSU@33208|Metazoa,3E41R@33213|Bilateria	33208|Metazoa	IQ	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_98250_1	1379698.RBG1_1C00001G0069	2.24e-58	206.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CHU_C,FlgD_ig,PKD,Peptidase_S8
k59_109456_1	158190.SpiGrapes_2787	1.03e-200	567.0	COG1129@1|root,COG1129@2|Bacteria,2J5EN@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K10441,ko:K10542,ko:K10548,ko:K17215	ko02010,map02010	M00212,M00214,M00216,M00221,M00593	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3,3.A.1.2.5	-	-	ABC_tran
k59_3805_1	118161.KB235920_gene6006	8.16e-45	150.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	tnpR	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
k59_150716_2	517418.Ctha_1164	7.87e-94	305.0	COG0841@1|root,COG0841@2|Bacteria,1FDHA@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_15777_1	7029.ACYPI46593-PA	9.96e-11	66.2	2D3M8@1|root,2SS02@2759|Eukaryota,3ANR4@33154|Opisthokonta,3C1MX@33208|Metazoa,3DH7H@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15777_2	13249.RPRC004498-PA	2.21e-227	643.0	2CNBX@1|root,2QV3V@2759|Eukaryota,39W09@33154|Opisthokonta,3BH5J@33208|Metazoa,3E62V@33213|Bilateria,42B7K@6656|Arthropoda,3T0MX@50557|Insecta,3EEBZ@33342|Paraneoptera	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_87075_2	642492.Clole_2082	3.29e-27	109.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_57769_1	530564.Psta_2541	1.37e-44	158.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_103803_1	1379698.RBG1_1C00001G1819	3.94e-36	144.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_21390_1	3218.PP1S440_11V6.1	1.37e-11	72.0	COG0749@1|root,KOG0950@2759|Eukaryota,37KZP@33090|Viridiplantae,3G7AS@35493|Streptophyta	35493|Streptophyta	A	Helicase and polymerase-containing protein	-	GO:0000018,GO:0000724,GO:0000725,GO:0000726,GO:0002200,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002566,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006282,GO:0006284,GO:0006302,GO:0006303,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007275,GO:0008094,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009314,GO:0009416,GO:0009628,GO:0009639,GO:0009640,GO:0009653,GO:0009791,GO:0009888,GO:0009892,GO:0009933,GO:0009987,GO:0010468,GO:0010564,GO:0010569,GO:0010605,GO:0016043,GO:0016445,GO:0016446,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016829,GO:0016835,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045738,GO:0045910,GO:0045934,GO:0046483,GO:0048507,GO:0048519,GO:0048523,GO:0048532,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051239,GO:0051259,GO:0051260,GO:0051301,GO:0051575,GO:0051716,GO:0051726,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0097681,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901987,GO:1902749,GO:1990067,GO:2000011,GO:2000026,GO:2000042,GO:2000779,GO:2000780,GO:2001020,GO:2001021	2.7.7.7	ko:K02349	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DNA_pol_A,Helicase_C
k59_145305_2	1349767.GJA_804	4.55e-32	127.0	COG1639@1|root,COG1639@2|Bacteria,1RASR@1224|Proteobacteria,2VR0D@28216|Betaproteobacteria,474B9@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_145305_3	575615.HMPREF0670_02182	1.81e-13	73.6	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG2207@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,PEPcase,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
k59_57225_1	448385.sce6188	1.83e-83	256.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_115114_1	7897.ENSLACP00000003032	1e-52	174.0	KOG1075@1|root,KOG1075@2759|Eukaryota,38Y7H@33154|Opisthokonta,3C5TR@33208|Metazoa,3DG8G@33213|Bilateria	33208|Metazoa	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103806_2	446469.Sked_14830	2.32e-06	52.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
k59_27906_1	768671.ThimaDRAFT_0100	2.36e-29	121.0	COG2864@1|root,COG2864@2|Bacteria,1QXP0@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_cB
k59_10099_1	215358.XP_010742932.1	4.07e-11	69.3	2CWBH@1|root,2RU3X@2759|Eukaryota,39UDV@33154|Opisthokonta,3BM7I@33208|Metazoa,3D3MF@33213|Bilateria,48DIG@7711|Chordata,49ACQ@7742|Vertebrata,49TID@7898|Actinopterygii	33208|Metazoa	L	Si ch73-382f3.1	-	-	-	-	-	-	-	-	-	-	-	-	THAP,Tnp_P_element
k59_133363_1	518766.Rmar_0238	1.81e-29	124.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,1FIYK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_186148_1	1379698.RBG1_1C00001G0688	6e-186	536.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k59_92210_1	1517681.HW45_22000	5.5e-21	94.4	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,1T34W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Phosphate	-	-	2.3.1.19,2.3.1.8	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921,R01174	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
k59_21418_1	686340.Metal_2049	4.57e-81	242.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1XFE6@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_74717_1	448385.sce3403	7.56e-14	70.9	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42QTE@68525|delta/epsilon subdivisions,2WN61@28221|Deltaproteobacteria,2YUPI@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_50598_1	7029.ACYPI29654-PA	7.41e-25	114.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A278@33154|Opisthokonta,3C5WU@33208|Metazoa,3DG3H@33213|Bilateria,422D9@6656|Arthropoda,3SR1F@50557|Insecta	33154|Opisthokonta	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	ko:K10443	-	-	-	-	ko00000,ko04121	-	-	-	Exo_endo_phos_2,RNase_H,RVT_1
k59_98771_1	1123073.KB899241_gene3211	8.03e-44	157.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1X3BK@135614|Xanthomonadales	135614|Xanthomonadales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_62844_1	1267533.KB906734_gene4016	1.5e-15	72.0	COG1695@1|root,COG1695@2|Bacteria,3Y8CC@57723|Acidobacteria,2JP3G@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
k59_62844_2	65071.PYU1_T011594	1.01e-32	126.0	COG0042@1|root,KOG2335@2759|Eukaryota,1MFAE@121069|Pythiales	121069|Pythiales	J	TRNA-dihydrouridine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_80719_1	504472.Slin_0858	8.96e-38	143.0	COG0535@1|root,COG0535@2|Bacteria,4NVQS@976|Bacteroidetes	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169010_2	29760.VIT_01s0146g00390.t01	3.67e-106	306.0	29XCM@1|root,2RXRI@2759|Eukaryota,37U8V@33090|Viridiplantae,3GHWM@35493|Streptophyta	35493|Streptophyta	S	ATP synthase protein YMF19	-	GO:0000276,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005773,GO:0009507,GO:0009536,GO:0016020,GO:0016469,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033177,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045259,GO:0045263,GO:0046872,GO:0046914,GO:0050897,GO:0098796,GO:0098798,GO:0098800	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	DUF1082,YMF19
k59_74726_1	1499967.BAYZ01000118_gene3290	6.18e-127	394.0	COG0058@1|root,COG0058@2|Bacteria,2NNZS@2323|unclassified Bacteria	2|Bacteria	G	Carbohydrate phosphorylase	malP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
k59_4401_1	1191523.MROS_0518	8.17e-11	67.8	COG1404@1|root,COG4677@1|root,COG1404@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,Pectate_lyase_3,fn3
k59_109986_1	1122599.AUGR01000014_gene618	7.38e-08	58.9	COG2165@1|root,COG2165@2|Bacteria,1NABA@1224|Proteobacteria,1SG2S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_50615_1	469383.Cwoe_3016	6.33e-21	92.8	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CPG8@84995|Rubrobacteria	84995|Rubrobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_50615_2	97139.C824_02223	3.47e-76	241.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,36UI2@31979|Clostridiaceae	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_10127_1	65672.G4TXN3	3.8e-12	73.6	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3NVKU@4751|Fungi,3UXZ9@5204|Basidiomycota,22CAJ@155619|Agaricomycetes,3H7KV@355688|Agaricomycetes incertae sedis	4751|Fungi	L	Retrotransposable element tf2 155 kda protein type 1-like	-	GO:0003674,GO:0003824,GO:0003964,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006278,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	Chromo,Peptidase_A2E,RVP_2,RVT_1,Retrotrans_gag,gag-asp_proteas,rve,zf-CCHC
k59_80741_2	981223.AIED01000082_gene2300	3.09e-08	54.7	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,3NKT2@468|Moraxellaceae	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans	slyD	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_121835_1	96561.Dole_3240	7.87e-54	174.0	COG1586@1|root,COG1586@2|Bacteria,1REQP@1224|Proteobacteria,42RVE@68525|delta/epsilon subdivisions,2WNJ5@28221|Deltaproteobacteria,2MJVH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	S-adenosylmethionine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	AdoMet_dc
k59_156696_1	1541065.JRFE01000050_gene2958	1.29e-126	375.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1G4U8@1117|Cyanobacteria,3VN9D@52604|Pleurocapsales	1117|Cyanobacteria	LV	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,HNH,RVT_1
k59_62864_2	2880.D8LJR7	2.96e-63	202.0	COG2131@1|root,KOG3127@2759|Eukaryota	2759|Eukaryota	F	dCMP deaminase activity	DCTD	GO:0003674,GO:0003824,GO:0004132,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046078,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_121837_1	644966.Tmar_2172	2.02e-28	111.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3WCEH@538999|Clostridiales incertae sedis	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_16323_1	400682.PAC_15711671	9.1e-51	182.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa	2759|Eukaryota	S	zinc finger, MYM-type	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_103854_1	126957.SMAR003178-PA	1.78e-11	70.1	2EMJ6@1|root,2SR73@2759|Eukaryota,38YZM@33154|Opisthokonta,3C1WR@33208|Metazoa,3DCHZ@33213|Bilateria	33208|Metazoa	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	PRE_C2HC
k59_133422_1	411469.EUBHAL_00379	1.11e-14	76.6	COG3437@1|root,COG3437@2|Bacteria,1UHZZ@1239|Firmicutes,25E8P@186801|Clostridia,25ZUA@186806|Eubacteriaceae	186801|Clostridia	KT	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_121842_2	48698.ENSPFOP00000020326	8.62e-90	286.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria,48QHZ@7711|Chordata,497ZU@7742|Vertebrata,4A5U1@7898|Actinopterygii	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_74741_3	1869.MB27_16260	0.000299	44.7	COG1876@1|root,COG1876@2|Bacteria,2IJGR@201174|Actinobacteria,4DEQ7@85008|Micromonosporales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	-	-	-	-	-	-	-	-	-	-	VanY
k59_145410_2	1121904.ARBP01000009_gene4192	0.000336	47.4	COG0526@1|root,COG0526@2|Bacteria,4NT1R@976|Bacteroidetes	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_180847_1	396588.Tgr7_2684	9.05e-82	253.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_110036_1	573413.Spirs_0161	1.88e-21	89.4	COG0745@1|root,COG0745@2|Bacteria,2J89I@203691|Spirochaetes	203691|Spirochaetes	T	response regulator	cheY-2	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_62874_1	1122179.KB890413_gene4948	1.31e-29	110.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_62874_2	1379698.RBG1_1C00001G1502	3.72e-179	510.0	COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_62874_3	1499967.BAYZ01000182_gene4428	2.52e-15	71.2	COG0599@1|root,COG0599@2|Bacteria,2NRHA@2323|unclassified Bacteria	2|Bacteria	O	Carboxymuconolactone decarboxylase family	rnhA	-	3.1.26.4,4.1.1.44	ko:K01607,ko:K03469	ko00362,ko01100,ko01120,ko01220,ko03030,map00362,map01100,map01120,map01220,map03030	-	R03470	RC00938	ko00000,ko00001,ko01000,ko03032	-	-	-	CMD
k59_69104_1	981085.XP_010100011.1	9.98e-66	205.0	COG0636@1|root,KOG0232@2759|Eukaryota	2759|Eukaryota	C	ATP hydrolysis coupled proton transport	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02155,ko:K02919	ko00190,ko00195,ko01100,ko03010,ko04142,ko04145,ko04721,ko04966,ko05110,ko05120,ko05152,ko05323,map00190,map00195,map01100,map03010,map04142,map04145,map04721,map04966,map05110,map05120,map05152,map05323	M00157,M00160,M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00194,ko03011	3.A.2.1,3.A.2.2	-	-	ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_69104_2	4572.TRIUR3_00082-P1	0.0	906.0	COG0056@1|root,KOG1353@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit alpha	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_115214_1	1340434.AXVA01000012_gene2957	2.08e-06	52.4	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_104464_1	649638.Trad_0621	1.87e-13	70.5	COG0329@1|root,COG0329@2|Bacteria,1WIBA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
k59_57926_1	1499967.BAYZ01000119_gene3214	4.81e-75	234.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
k59_169751_1	231434.JQJH01000002_gene2599	8.14e-14	75.9	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2TT31@28211|Alphaproteobacteria,3N9T2@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	4Fe-4S single cluster domain	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
k59_104480_1	631362.Thi970DRAFT_04260	0.000146	48.1	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1WYEK@135613|Chromatiales	135613|Chromatiales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_99465_1	1254432.SCE1572_44870	7.87e-65	214.0	COG3104@1|root,COG3104@2|Bacteria,1P6K2@1224|Proteobacteria	1224|Proteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_63550_1	7955.ENSDARP00000106282	7.85e-67	226.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria,48DPU@7711|Chordata,49A9G@7742|Vertebrata	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_40098_1	13249.RPRC008993-PA	8.44e-13	66.6	2D16C@1|root,2SGW5@2759|Eukaryota,3ANBW@33154|Opisthokonta,3C1V9@33208|Metazoa,3DBZC@33213|Bilateria,421H1@6656|Arthropoda,3SQ5H@50557|Insecta,3EE7N@33342|Paraneoptera	33208|Metazoa	S	hAT family C-terminal dimerisation region	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_40101_1	990285.RGCCGE502_20275	4.74e-101	299.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TUSA@28211|Alphaproteobacteria,4B809@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_40101_2	390874.Tpet_1740	3.12e-66	204.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_115677_1	342113.DM82_1686	7.88e-06	53.1	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K04784,ko:K04786	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,TauD,Thioesterase
k59_128219_1	7897.ENSLACP00000001098	1.27e-29	119.0	2CNDJ@1|root,2QVFB@2759|Eukaryota,39MN8@33154|Opisthokonta,3CP8H@33208|Metazoa,3E5D2@33213|Bilateria,48RT0@7711|Chordata,49N6G@7742|Vertebrata	33208|Metazoa	S	Transposase IS4	-	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0016604,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0070013	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_69611_1	485913.Krac_2962	1.28e-71	230.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
k59_69615_1	416591.Tlet_1847	3.51e-83	269.0	COG0495@1|root,COG0495@2|Bacteria,2GC3Z@200918|Thermotogae	200918|Thermotogae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_128228_2	1453505.JASY01000008_gene613	7.02e-19	87.4	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,1I19Q@117743|Flavobacteriia,2NTJJ@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_10645_1	1379698.RBG1_1C00001G0360	6.45e-21	90.1	COG2928@1|root,COG2928@2|Bacteria,2NR55@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_10645_2	1408422.JHYF01000003_gene819	1.4e-14	77.4	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,36KWH@31979|Clostridiaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_81209_1	330214.NIDE0204	7.85e-35	127.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,3J13F@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_81209_2	251221.35212389	6e-67	209.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_110482_1	517418.Ctha_0112	2.68e-21	94.4	COG1629@1|root,COG4771@2|Bacteria,1FEX4@1090|Chlorobi	1090|Chlorobi	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
k59_110482_2	72228.T5AHY6	7.59e-11	65.9	KOG0266@1|root,KOG0272@1|root,KOG0266@2759|Eukaryota,KOG0272@2759|Eukaryota,38B6D@33154|Opisthokonta,3NYUK@4751|Fungi,3QKYQ@4890|Ascomycota,21RM6@147550|Sordariomycetes,3TUQU@5125|Hypocreales	4751|Fungi	S	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,PNP_UDP_1,WD40
k59_10653_1	1255043.TVNIR_2220	1.18e-146	434.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_87038_1	1379698.RBG1_1C00001G1332	2.62e-27	105.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
k59_87038_2	1121396.KB893112_gene2019	0.000229	48.1	COG2208@1|root,COG3850@1|root,COG2208@2|Bacteria,COG3850@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MIMK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	5TM-5TMR_LYT,Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2
k59_115714_1	518766.Rmar_1197	7.25e-23	98.6	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1FJWR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_115714_2	1156937.MFUM_70018	7.77e-22	89.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia,37GYP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_115714_3	243233.MCA1501	8.17e-13	70.9	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XEHZ@135618|Methylococcales	135618|Methylococcales	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_163720_1	946483.Cenrod_0792	4.03e-32	127.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,4AA5A@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
k59_10663_2	717231.Flexsi_2164	5.03e-15	70.9	COG1188@1|root,COG1188@2|Bacteria,2GFZA@200930|Deferribacteres	200930|Deferribacteres	J	S4 RNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	S4
k59_10663_3	317013.NY99_02035	0.000277	49.3	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1X4BU@135614|Xanthomonadales	135614|Xanthomonadales	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_57737_1	1348635.BBJY01000026_gene2281	5.84e-66	211.0	COG1887@1|root,COG1887@2|Bacteria,1P3NC@1224|Proteobacteria,1SPGX@1236|Gammaproteobacteria,1XWIT@135623|Vibrionales	135623|Vibrionales	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115715_1	1165841.SULAR_09619	3.54e-58	186.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,42TT9@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k59_4901_1	1379270.AUXF01000003_gene3362	2.59e-22	94.4	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	nhaR	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_4901_2	522306.CAP2UW1_2179	4.54e-24	95.5	COG1544@1|root,COG1544@2|Bacteria,1N8CQ@1224|Proteobacteria,2VVX7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
k59_45787_1	1191523.MROS_0571	1.5e-170	485.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	yajO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_115716_1	1047013.AQSP01000138_gene1045	2.99e-10	64.7	COG0613@1|root,COG0613@2|Bacteria,2NPWD@2323|unclassified Bacteria	2|Bacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
k59_45788_1	1232410.KI421417_gene2752	2.98e-36	135.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,43S30@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glycosyltransferase family 20	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
k59_45788_2	278963.ATWD01000002_gene558	4.17e-18	82.8	COG1877@1|root,COG1877@2|Bacteria	2|Bacteria	G	trehalose biosynthetic process	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
k59_181179_1	1121481.AUAS01000001_gene4650	5.62e-22	101.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,47JZB@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_115724_2	526227.Mesil_2566	1.86e-64	213.0	COG0232@1|root,COG0232@2|Bacteria,1WI39@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the dGTPase family. Type 2 subfamily	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_87055_1	106582.XP_004561507.1	8.21e-08	57.4	2E1A2@1|root,2S8MX@2759|Eukaryota,3A99F@33154|Opisthokonta,3BV65@33208|Metazoa,3DBZ5@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4806
k59_110508_1	1379698.RBG1_1C00001G1744	1.71e-70	216.0	COG2018@1|root,COG2018@2|Bacteria,2NQXH@2323|unclassified Bacteria	2|Bacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
k59_110508_2	1379698.RBG1_1C00001G1743	5.29e-99	306.0	COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_28472_1	244582.JQAK01000002_gene463	2.16e-83	263.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2TRPW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_57764_1	760568.Desku_3291	2.64e-87	270.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_5403_1	292459.STH404	6.58e-18	85.9	COG0702@1|root,COG0702@2|Bacteria,1VEC8@1239|Firmicutes,25BCI@186801|Clostridia	186801|Clostridia	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
k59_46331_2	400682.PAC_15711671	4.37e-75	258.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa	2759|Eukaryota	S	zinc finger, MYM-type	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_11164_1	118161.KB235922_gene1001	1.68e-76	243.0	COG3039@1|root,COG3039@2|Bacteria,1G3IA@1117|Cyanobacteria,3VMBS@52604|Pleurocapsales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_11164_2	118161.KB235922_gene1002	2.02e-43	144.0	2D6H4@1|root,32TM8@2|Bacteria,1G875@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_116189_1	6669.EFX81166	6.37e-09	63.9	2AENI@1|root,2RYW1@2759|Eukaryota,39ZI9@33154|Opisthokonta,3BQBS@33208|Metazoa,3D2GS@33213|Bilateria,41TJ8@6656|Arthropoda	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46332_1	1177154.Y5S_02582	0.000708	48.1	COG3266@1|root,COG5492@1|root,COG3266@2|Bacteria,COG5492@2|Bacteria,1R8Z4@1224|Proteobacteria,1S0IR@1236|Gammaproteobacteria,1XMN8@135619|Oceanospirillales	135619|Oceanospirillales	N	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_5414_1	667014.Thein_0405	1.47e-51	176.0	COG2221@1|root,COG2221@2|Bacteria,2GGYD@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR
k59_15852_1	1158338.JNLJ01000001_gene332	1.43e-05	44.7	COG1837@1|root,COG1837@2|Bacteria,2G4BD@200783|Aquificae	200783|Aquificae	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_68598_1	118168.MC7420_384	9.82e-68	216.0	COG0171@1|root,COG0171@2|Bacteria	2|Bacteria	H	NAD+ synthase (glutamine-hydrolyzing) activity	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
k59_185655_2	1397666.RS24_00788	2.09e-65	209.0	294XI@1|root,2ZSAH@2|Bacteria,1RDZH@1224|Proteobacteria,2UJKD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
k59_98325_1	7029.ACYPI47154-PA	0.000464	47.8	KOG1121@1|root,KOG1121@2759|Eukaryota,39TTD@33154|Opisthokonta,3BCXB@33208|Metazoa,3CYBV@33213|Bilateria,421ZD@6656|Arthropoda,3SQPW@50557|Insecta	33208|Metazoa	L	RNA polymerase II regulatory region DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_27530_1	675817.VDA_003391	1.47e-37	140.0	COG0475@1|root,COG0475@2|Bacteria,1NRVM@1224|Proteobacteria	1224|Proteobacteria	P	glutathione-regulated potassium exporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80287_1	378806.STAUR_0336	5.01e-46	163.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42R6X@68525|delta/epsilon subdivisions,2WMY9@28221|Deltaproteobacteria,2Z18Z@29|Myxococcales	28221|Deltaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_115303_1	762376.AXYL_05107	2.52e-46	150.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,2VSZH@28216|Betaproteobacteria,3T4FT@506|Alcaligenaceae	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_39818_1	1158607.UAU_00923	7.58e-14	71.6	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HTTR@91061|Bacilli,4B4J7@81852|Enterococcaceae	91061|Bacilli	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
k59_39818_2	1196083.SALWKB12_1844	2.03e-08	58.5	COG1053@1|root,COG1902@1|root,COG1053@2|Bacteria,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,2KR8Y@206351|Neisseriales	206351|Neisseriales	C	Oxidoreductase, FAD FMN-binding protein	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_FMN
k59_62986_1	1123023.JIAI01000001_gene7025	2.98e-48	174.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4DYMP@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_16492_2	744872.Spica_1935	7.94e-13	69.3	COG0697@1|root,COG0697@2|Bacteria,2JA9I@203691|Spirochaetes	203691|Spirochaetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_28072_1	926550.CLDAP_02040	2.76e-142	419.0	COG3385@1|root,COG3385@2|Bacteria,2G7UE@200795|Chloroflexi	200795|Chloroflexi	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_151361_1	1203554.HMPREF1476_01470	2.96e-31	129.0	COG4690@1|root,COG4690@2|Bacteria,1QDV9@1224|Proteobacteria,2W18X@28216|Betaproteobacteria,4PR0B@995019|Sutterellaceae	28216|Betaproteobacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
k59_33734_1	3880.AES88255	1.59e-72	219.0	COG0197@1|root,KOG3422@2759|Eukaryota,37UTS@33090|Viridiplantae,3GIPW@35493|Streptophyta,4JU72@91835|fabids	35493|Streptophyta	J	50S ribosomal protein	rpl16	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_33734_2	13333.ERM96122	5.57e-72	217.0	COG0093@1|root,KOG0901@2759|Eukaryota,37UWF@33090|Viridiplantae,3GIPC@35493|Streptophyta	35493|Streptophyta	J	Belongs to the universal ribosomal protein uL14 family	rpl14	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0008150,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0015934,GO:0019843,GO:0031974,GO:0031976,GO:0031984,GO:0032991,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0070013,GO:0070180,GO:0097159,GO:0098798,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_33734_3	4155.Migut.D01328.1.p	7.77e-71	215.0	COG0096@1|root,KOG1754@2759|Eukaryota,37UMN@33090|Viridiplantae,3GIWP@35493|Streptophyta,44TEK@71274|asterids	35493|Streptophyta	J	Ribosomal protein S8	rps8	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14,Ribosomal_L16,Ribosomal_S8
k59_33734_5	13333.ERM96121	9.67e-81	240.0	COG0100@1|root,KOG0408@2759|Eukaryota,37UVR@33090|Viridiplantae,3GJ9B@35493|Streptophyta	35493|Streptophyta	J	Belongs to the universal ribosomal protein uS11 family	rps11	GO:0000028,GO:0000313,GO:0000314,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0031974,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070013,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0098798,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_33734_6	4113.PGSC0003DMT400036532	3.19e-196	549.0	COG0202@1|root,2QRS7@2759|Eukaryota,37QVG@33090|Viridiplantae,3GHDB@35493|Streptophyta,44N87@71274|asterids	35493|Streptophyta	K	Bacterial RNA polymerase, alpha chain C terminal domain	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0031976,GO:0031984,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_33734_7	4155.Migut.D01433.1.p	4.34e-106	307.0	COG1290@1|root,KOG4663@2759|Eukaryota,37NKU@33090|Viridiplantae,3G85T@35493|Streptophyta,44QX6@71274|asterids	35493|Streptophyta	C	Cytochrome b(C-terminal)/b6/petD	petD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02637	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B_C
k59_33734_9	981085.XP_010089870.1	9.05e-111	321.0	COG1290@1|root,KOG4663@2759|Eukaryota,37QS7@33090|Viridiplantae,3GHBB@35493|Streptophyta,4JPQB@91835|fabids	35493|Streptophyta	C	cytochrome b6	petB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02635,ko:K02704	ko00195,ko01100,map00195,map01100	M00161,M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_33734_10	29730.Gorai.010G031500.1	2.14e-42	139.0	2E1MV@1|root,2S8Y7@2759|Eukaryota,37WT7@33090|Viridiplantae,3GKK7@35493|Streptophyta	35493|Streptophyta	S	One of the components of the core complex of photosystem II (PSII), required for its stability and or assembly. PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbH	-	-	ko:K02709	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbH
k59_121986_1	264732.Moth_0731	9.73e-21	91.7	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,24AHX@186801|Clostridia,42FZR@68295|Thermoanaerobacterales	186801|Clostridia	S	Zn-dependent hydrolases of the	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_121986_2	243164.DET0822	4.77e-16	75.9	COG1371@1|root,COG1371@2|Bacteria,2G7BQ@200795|Chloroflexi,34DDY@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
k59_39848_1	1379698.RBG1_1C00001G1262	2.24e-18	82.4	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02458,ko:K02671	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	N_methyl
k59_103971_1	926692.AZYG01000040_gene1543	4.67e-50	182.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WA9Z@53433|Halanaerobiales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_110176_1	13735.ENSPSIP00000001008	4.24e-25	101.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A35Z@33154|Opisthokonta,3BQYF@33208|Metazoa,3D7GC@33213|Bilateria,48EZY@7711|Chordata,49BMJ@7742|Vertebrata	33208|Metazoa	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_80897_1	59374.Fisuc_0722	2.85e-14	77.8	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_21678_1	500635.MITSMUL_03985	8.59e-56	192.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4H32B@909932|Negativicutes	909932|Negativicutes	H	Belongs to the precorrin methyltransferase family	cobA	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_127941_1	106370.Francci3_4185	2.33e-20	95.5	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Cu_amine_oxidN1,NHL,Pkinase
k59_110188_1	416269.APL_0771	2.2e-52	184.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1Y76S@135625|Pasteurellales	135625|Pasteurellales	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_57416_1	7029.ACYPI003540-PA	3e-111	359.0	28M7P@1|root,2QTQS@2759|Eukaryota,39Z9X@33154|Opisthokonta,3BNGS@33208|Metazoa,3D442@33213|Bilateria	33208|Metazoa	S	cellular response to interferon-beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF4806
k59_28131_1	102107.XP_008244832.1	6.71e-53	169.0	2C63X@1|root,2S2ZC@2759|Eukaryota,37VFD@33090|Viridiplantae,3GJPI@35493|Streptophyta,4JW29@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_28131_2	3649.evm.TU.contig_32646.1	1.06e-189	526.0	COG1845@1|root,KOG4664@2759|Eukaryota,37QER@33090|Viridiplantae,3G8C5@35493|Streptophyta,3HY38@3699|Brassicales	35493|Streptophyta	C	cytochrome c oxidase subunit 3	cox3	-	-	ko:K02262	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX3
k59_86737_1	13037.EHJ73827	8.56e-38	149.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,420TT@6656|Arthropoda,3SQX5@50557|Insecta,449FF@7088|Lepidoptera	33208|Metazoa	J	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.3.1.15,2.4.2.29	ko:K13506,ko:K15407	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R03789,R09380,R10209	RC00004,RC00039,RC00041,RC00063	ko00000,ko00001,ko00002,ko01000,ko01004,ko03016	-	-	-	Exo_endo_phos_2,RVT_1
k59_133596_1	1123288.SOV_1c00540	9.05e-10	65.5	COG1629@1|root,COG4771@2|Bacteria,1UK28@1239|Firmicutes,4H9AZ@909932|Negativicutes	909932|Negativicutes	P	TonB-dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_74922_1	575540.Isop_1103	1.23e-22	100.0	COG3808@1|root,COG3808@2|Bacteria,2IXUH@203682|Planctomycetes	203682|Planctomycetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K01507,ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_122041_1	1304888.ATWF01000001_gene2187	2.04e-43	158.0	COG0143@1|root,COG0143@2|Bacteria,2GF31@200930|Deferribacteres	200930|Deferribacteres	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_104005_1	63737.Npun_F6362	1.7e-05	52.4	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HKMC@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11354	ko02020,map02020	M00510	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4
k59_28143_1	713586.KB900536_gene2158	1.14e-13	77.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RY0I@1236|Gammaproteobacteria,1X2IT@135613|Chromatiales	135613|Chromatiales	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_86745_1	497964.CfE428DRAFT_0041	0.000124	44.3	COG0330@1|root,COG0330@2|Bacteria,46TVK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_80929_1	27923.ML398337a-PA	7.27e-12	75.5	2CYA3@1|root,2S348@2759|Eukaryota,3A598@33154|Opisthokonta,3BS6R@33208|Metazoa	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371
k59_35336_1	871963.Desdi_1588	9.11e-17	84.3	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,260WC@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_82273_1	633697.EubceDRAFT1_0280	2.51e-11	68.9	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VZS@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_17692_1	1111479.AXAR01000001_gene118	1.31e-20	95.9	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli	91061|Bacilli	K	Transcriptional	rbsR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_135136_1	362976.HQ_1313A	2.04e-54	188.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_129265_1	979556.MTES_2195	8.29e-11	67.4	COG0438@1|root,COG0438@2|Bacteria,2IA7N@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_135140_1	926566.Terro_0192	4.2e-40	147.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria,2JI94@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_135140_2	748727.CLJU_c18100	5.36e-08	55.5	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,36ETV@31979|Clostridiaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_164515_1	7668.SPU_009092-tr	5.03e-08	61.2	2EZB0@1|root,2T0NS@2759|Eukaryota	7668.SPU_009092-tr|-	S	SCAN domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111656_1	1379698.RBG1_1C00001G0350	8.19e-48	175.0	COG1196@1|root,COG1196@2|Bacteria,2NNSS@2323|unclassified Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146892_1	936573.HMPREF1147_2280	6.89e-65	214.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H25Q@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_164523_1	6412.HelroP165647	4.11e-50	177.0	2CY9X@1|root,2S32T@2759|Eukaryota,3A52K@33154|Opisthokonta,3BS0M@33208|Metazoa,3D96Q@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_182074_1	4572.TRIUR3_00337-P1	1.82e-95	279.0	COG0049@1|root,KOG3291@2759|Eukaryota,37YX8@33090|Viridiplantae,3GNS6@35493|Streptophyta,3KTYP@4447|Liliopsida,3IAPX@38820|Poales	35493|Streptophyta	J	ribosomal protein S7	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S7
k59_182074_2	3880.AES69829	4.81e-179	523.0	COG0048@1|root,COG0049@1|root,COG1007@1|root,KOG1750@2759|Eukaryota,KOG3291@2759|Eukaryota,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,4JNJF@91835|fabids	35493|Streptophyta	C	NAD(P)H-quinone oxidoreductase subunit 2	ndhB	-	1.6.5.3	ko:K02992,ko:K05573	ko00190,ko01100,ko03010,map00190,map01100,map03010	M00145,M00178,M00179	R11945	RC00061	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	Proton_antipo_M
k59_182074_3	3880.AES69829	2.68e-164	484.0	COG0048@1|root,COG0049@1|root,COG1007@1|root,KOG1750@2759|Eukaryota,KOG3291@2759|Eukaryota,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,4JNJF@91835|fabids	35493|Streptophyta	C	NAD(P)H-quinone oxidoreductase subunit 2	ndhB	-	1.6.5.3	ko:K02992,ko:K05573	ko00190,ko01100,ko03010,map00190,map01100,map03010	M00145,M00178,M00179	R11945	RC00061	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	Proton_antipo_M
k59_182074_5	3712.Bo5g098620.1	1e-16	75.5	2E7CP@1|root,2R1P8@2759|Eukaryota,383D7@33090|Viridiplantae,3GWXB@35493|Streptophyta,3I19M@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105831_1	400682.PAC_15705505	2.38e-42	157.0	28MXD@1|root,2QUFX@2759|Eukaryota,38TCJ@33154|Opisthokonta,3BIIF@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76479_1	593750.Metfor_0459	1.95e-17	87.4	COG3635@1|root,arCOG01696@2157|Archaea,2XTE8@28890|Euryarchaeota,2NAHE@224756|Methanomicrobia	224756|Methanomicrobia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
k59_152744_1	1499967.BAYZ01000050_gene2877	1.16e-35	128.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
k59_152744_2	1304885.AUEY01000001_gene3202	1.67e-24	95.5	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2MJU4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_132_1	1288963.ADIS_4384	5.11e-51	178.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,47M2W@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
k59_29484_1	90675.XP_010462540.1	2.87e-64	222.0	28HC0@1|root,2QPQD@2759|Eukaryota,37QN4@33090|Viridiplantae,3GHQQ@35493|Streptophyta	35493|Streptophyta	S	Zinc finger MYM-type protein 1-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_158659_1	1304885.AUEY01000009_gene1949	4.93e-109	325.0	COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,43CQR@68525|delta/epsilon subdivisions,2X7Y7@28221|Deltaproteobacteria,2MPPF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_141024_1	938288.HG326224_gene1448	1.27e-05	52.4	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,268YA@186813|unclassified Clostridiales	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k59_141024_2	331869.BAL199_04109	0.000343	45.1	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,4BR84@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_99957_1	1379281.AVAG01000021_gene1080	1.12e-63	207.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,2MERM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,SHOCT,zinc_ribbon_2
k59_158666_1	756272.Plabr_3381	1.24e-83	259.0	28MEN@1|root,2ZASA@2|Bacteria,2IZ1H@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_17720_3	344747.PM8797T_14219	2.63e-13	75.5	COG1381@1|root,COG1381@2|Bacteria,2IZU9@203682|Planctomycetes	203682|Planctomycetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_17720_4	517417.Cpar_0022	2.57e-21	92.4	COG0423@1|root,COG0423@2|Bacteria,1FDA0@1090|Chlorobi	1090|Chlorobi	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_29507_1	7029.ACYPI061343-PA	2.42e-20	89.4	29K1R@1|root,2RTAM@2759|Eukaryota,39YR1@33154|Opisthokonta,3BPA4@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11894_1	67315.JOBD01000012_gene608	3.03e-07	53.9	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GKQG@201174|Actinobacteria	201174|Actinobacteria	DT	Forkhead associated domain	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
k59_11894_2	985255.APHJ01000035_gene40	3.64e-29	115.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HWXA@117743|Flavobacteriia,2P77F@244698|Gillisia	976|Bacteroidetes	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_35385_1	1499967.BAYZ01000060_gene6006	1.75e-38	137.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,2NPJ5@2323|unclassified Bacteria	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
k59_35394_1	330214.NIDE4168	7.86e-34	134.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,3J0Y7@40117|Nitrospirae	40117|Nitrospirae	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_6056_1	1191523.MROS_1635	5.37e-164	484.0	COG0046@1|root,COG0046@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_182128_1	448385.sce7837	1.16e-86	277.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria,4340K@68525|delta/epsilon subdivisions,2X4FG@28221|Deltaproteobacteria,2YYX6@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
k59_117562_1	1279009.ADICEAN_00454	8.4e-57	195.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_88270_1	1278307.KB907057_gene2644	1.44e-81	255.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,2QJ5B@267894|Psychromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_135202_1	1392489.JPOL01000002_gene523	5.28e-13	75.1	COG0457@1|root,COG1506@1|root,COG0457@2|Bacteria,COG1506@2|Bacteria,4PMMI@976|Bacteroidetes,1IKUM@117743|Flavobacteriia	976|Bacteroidetes	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6081_2	592015.HMPREF1705_02152	2.36e-23	104.0	COG0457@1|root,COG3359@1|root,COG0457@2|Bacteria,COG3359@2|Bacteria,3TATQ@508458|Synergistetes	508458|Synergistetes	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
k59_105920_1	764299.STRIC_2423	2.14e-21	97.8	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,4HFI7@91061|Bacilli	91061|Bacilli	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
k59_41290_1	1254432.SCE1572_47065	2.82e-92	286.0	COG3507@1|root,COG3507@2|Bacteria,1QS8P@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_35455_1	1232410.KI421424_gene1792	2.43e-79	255.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,43TW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_164604_1	56780.SYN_00568	2.2e-68	228.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_105931_1	1121406.JAEX01000005_gene3125	8.71e-76	244.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2M8CP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_88285_1	1565129.JSFF01000004_gene3234	2.36e-34	126.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,2QBRC@267890|Shewanellaceae	1236|Gammaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_88285_2	28229.ND2E_3091	1.78e-23	92.0	2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,2Q7AG@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
k59_182153_1	1379698.RBG1_1C00001G1742	2.8e-121	355.0	COG2805@1|root,COG2805@2|Bacteria,2NNR7@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_88286_2	159749.K0S6X5	1.05e-25	113.0	COG0024@1|root,KOG2738@2759|Eukaryota,2XF99@2836|Bacillariophyta	2836|Bacillariophyta	O	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_6117_1	7029.ACYPI21748-PA	1.37e-49	193.0	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa	7029.ACYPI21748-PA|-	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_164619_2	926569.ANT_26040	9.78e-31	116.0	COG5433@1|root,COG5433@2|Bacteria,2G91G@200795|Chloroflexi	200795|Chloroflexi	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
k59_46969_1	203119.Cthe_0484	6.88e-68	220.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia,3WI89@541000|Ruminococcaceae	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
k59_46969_2	1528098.NOVO_01015	9.39e-18	84.7	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria,47EYS@766|Rickettsiales	766|Rickettsiales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_88073_2	1415778.JQMM01000001_gene1282	1.42e-05	47.8	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1J5MY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2206 HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_117419_1	450851.PHZ_p0142	4.25e-41	154.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,2KJGW@204458|Caulobacterales	204458|Caulobacterales	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	-	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k59_146778_1	675806.VII_003496	2.46e-21	99.4	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1THG0@1236|Gammaproteobacteria,1XVI6@135623|Vibrionales	135623|Vibrionales	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_105694_1	643562.Daes_0386	4.66e-46	164.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,42M93@68525|delta/epsilon subdivisions,2WK5I@28221|Deltaproteobacteria,2MBEI@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_52843_1	7897.ENSLACP00000005873	4.35e-139	423.0	2BUCY@1|root,2S232@2759|Eukaryota,3A3U2@33154|Opisthokonta,3BSU1@33208|Metazoa,3D598@33213|Bilateria,48J86@7711|Chordata,49FDD@7742|Vertebrata	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_82207_1	7897.ENSLACP00000003088	1.08e-35	133.0	29Q9H@1|root,2RX81@2759|Eukaryota,39ZQJ@33154|Opisthokonta,3BNMR@33208|Metazoa,3D7EF@33213|Bilateria	33208|Metazoa	-	-	-	-	-	ko:K20283	-	-	-	-	ko00000,ko04131	-	-	-	-
k59_41116_1	768671.ThimaDRAFT_3018	1.68e-41	150.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,1RYKV@1236|Gammaproteobacteria,1X06D@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_41116_2	497321.C664_05611	1.37e-27	105.0	2BZBC@1|root,32R4Q@2|Bacteria,1RICW@1224|Proteobacteria,2VY1H@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5892_1	767817.Desgi_1148	1.24e-10	67.4	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_105714_1	7029.ACYPI068226-PA	2.18e-06	55.5	2CYPK@1|root,2S5GH@2759|Eukaryota,3A5FF@33154|Opisthokonta,3BRJC@33208|Metazoa,3D8HY@33213|Bilateria,42044@6656|Arthropoda,3SPJR@50557|Insecta	2759|Eukaryota	S	Transposase protein	-	-	-	-	-	-	-	-	-	-	-	-	THAP,Tnp_P_element,Tnp_P_element_C
k59_146794_1	575540.Isop_0439	1.5e-16	77.8	COG0479@1|root,COG0479@2|Bacteria,2IX7J@203682|Planctomycetes	203682|Planctomycetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
k59_64601_2	8081.XP_008425483.1	6.35e-111	347.0	29YJV@1|root,2RXU5@2759|Eukaryota,3A0FB@33154|Opisthokonta,3BPYT@33208|Metazoa,3D6GB@33213|Bilateria,48G4U@7711|Chordata,49D4K@7742|Vertebrata,4A7F2@7898|Actinopterygii	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135044_1	10224.XP_002739538.2	1.6e-49	171.0	2CYJA@1|root,2S4S7@2759|Eukaryota,3A62Z@33154|Opisthokonta,3BTAY@33208|Metazoa,3E403@33213|Bilateria	33208|Metazoa	S	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	FLYWCH,MULE
k59_88101_2	8153.XP_005930955.1	4.69e-10	63.5	KOG3545@1|root,KOG4193@1|root,KOG4729@1|root,KOG3545@2759|Eukaryota,KOG4193@2759|Eukaryota,KOG4729@2759|Eukaryota,38D0U@33154|Opisthokonta,3BCMA@33208|Metazoa,3CRTM@33213|Bilateria,484Y4@7711|Chordata,48YXP@7742|Vertebrata,49R9Z@7898|Actinopterygii	33208|Metazoa	T	Belongs to the G-protein coupled receptor 2 family	LPHN3	GO:0001764,GO:0003674,GO:0004888,GO:0004930,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005911,GO:0006928,GO:0007154,GO:0007155,GO:0007165,GO:0007186,GO:0007275,GO:0007399,GO:0007416,GO:0007417,GO:0007420,GO:0007610,GO:0007626,GO:0008150,GO:0009410,GO:0009987,GO:0010033,GO:0010243,GO:0014070,GO:0016020,GO:0016021,GO:0016043,GO:0016477,GO:0022008,GO:0022607,GO:0022610,GO:0023052,GO:0030054,GO:0030154,GO:0030424,GO:0031224,GO:0031226,GO:0031987,GO:0032501,GO:0032502,GO:0038023,GO:0040011,GO:0042220,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0043279,GO:0044085,GO:0044087,GO:0044089,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048513,GO:0048518,GO:0048522,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051239,GO:0051240,GO:0051674,GO:0051716,GO:0051960,GO:0051962,GO:0051963,GO:0051965,GO:0060089,GO:0060322,GO:0060359,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0072347,GO:0097458,GO:0098609,GO:0098742,GO:0120025,GO:1901698,GO:1901700,GO:2000026	-	ko:K04593,ko:K04594	-	-	-	-	ko00000,ko04030	-	-	-	7tm_2,GAIN,GPS,Gal_Lectin,HRM,Latrophilin,OLF
k59_64608_1	439235.Dalk_2188	5.6e-35	131.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_152663_1	349521.HCH_04555	1.25e-41	154.0	COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria,1XIN9@135619|Oceanospirillales	135619|Oceanospirillales	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
k59_5908_1	316056.RPC_4607	0.000114	50.1	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_11781_1	861299.J421_1776	1.52e-13	69.3	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_11781_2	1501391.LG35_00650	5.24e-25	106.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,2FMJ3@200643|Bacteroidia,22UVJ@171550|Rikenellaceae	976|Bacteroidetes	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_52860_2	1219049.SP5_040_00440	3.24e-10	59.7	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2K0R5@204457|Sphingomonadales	204457|Sphingomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_29392_1	7029.ACYPI47019-PA	2.44e-72	255.0	28IIP@1|root,2QQVP@2759|Eukaryota,39TA7@33154|Opisthokonta,3CNWS@33208|Metazoa,3D3DK@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_88131_1	1408442.JADE01000007_gene821	7.65e-07	50.4	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2YPMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	Cj0420	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_35258_1	1317122.ATO12_24585	1.43e-41	142.0	COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,1I2P2@117743|Flavobacteriia,2YIQT@290174|Aquimarina	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_135064_1	7029.ACYPI48175-PA	2.34e-16	89.4	28IIP@1|root,2QQVP@2759|Eukaryota,39TA7@33154|Opisthokonta,3CNWS@33208|Metazoa,3D3DK@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_158564_1	344747.PM8797T_19632	1.51e-68	228.0	COG0367@1|root,COG0367@2|Bacteria,2IXAI@203682|Planctomycetes	203682|Planctomycetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_99844_1	96561.Dole_1347	2.72e-125	382.0	COG0471@1|root,COG2204@1|root,COG0471@2|Bacteria,COG2204@2|Bacteria,1MUSA@1224|Proteobacteria,42QBN@68525|delta/epsilon subdivisions,2WK9R@28221|Deltaproteobacteria,2MJF9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp
k59_82236_1	1254432.SCE1572_33325	3.45e-25	108.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
k59_117478_1	1379698.RBG1_1C00001G1808	1.9e-12	63.2	COG1828@1|root,COG1828@2|Bacteria,2NQ45@2323|unclassified Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
k59_117478_2	1307759.JOMJ01000003_gene457	1.57e-31	122.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2M8CV@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_41157_2	933262.AXAM01000030_gene823	1.67e-14	77.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WP0E@28221|Deltaproteobacteria,2MJVK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_47017_1	509635.N824_01490	1.22e-24	108.0	COG0526@1|root,COG0526@2|Bacteria,4NK4G@976|Bacteroidetes,1IQJW@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
k59_99874_1	7091.BGIBMGA001644-TA	3.05e-54	194.0	COG5193@1|root,KOG2590@2759|Eukaryota,38EPU@33154|Opisthokonta,3B9XE@33208|Metazoa,3CTZE@33213|Bilateria,41XZC@6656|Arthropoda,3SIJ0@50557|Insecta,446CB@7088|Lepidoptera	33208|Metazoa	JO	Domain in the RNA-binding Lupus La protein; unknown function	LARP1B	GO:0000001,GO:0000003,GO:0000212,GO:0000226,GO:0000278,GO:0000280,GO:0000339,GO:0000932,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007005,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007053,GO:0007140,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0008150,GO:0008152,GO:0008187,GO:0008190,GO:0008266,GO:0008283,GO:0008494,GO:0009058,GO:0009059,GO:0009605,GO:0009719,GO:0009790,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010494,GO:0010506,GO:0010508,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0014070,GO:0016043,GO:0016239,GO:0016241,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031331,GO:0031369,GO:0031667,GO:0031929,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033301,GO:0034046,GO:0034248,GO:0034249,GO:0034250,GO:0034641,GO:0034645,GO:0035186,GO:0035556,GO:0035690,GO:0035770,GO:0036464,GO:0038202,GO:0042221,GO:0042493,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043487,GO:0043488,GO:0043489,GO:0043603,GO:0043604,GO:0043900,GO:0043902,GO:0043903,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045069,GO:0045070,GO:0045182,GO:0045448,GO:0045472,GO:0045727,GO:0045934,GO:0046677,GO:0048027,GO:0048232,GO:0048255,GO:0048285,GO:0048308,GO:0048311,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048609,GO:0048856,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051225,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051321,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051716,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0070717,GO:0070887,GO:0070925,GO:0071236,GO:0071310,GO:0071362,GO:0071407,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0072752,GO:0080090,GO:0090079,GO:0090306,GO:0097159,GO:0097305,GO:0097306,GO:0097327,GO:0140013,GO:1901355,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902369,GO:1902373,GO:1903046,GO:1903311,GO:1903312,GO:1903900,GO:1903902,GO:1990904,GO:1990928,GO:2000112,GO:2000113	-	ko:K18757	-	-	-	-	ko00000,ko03019	-	-	-	La
k59_17670_1	1122197.ATWI01000013_gene2311	8.52e-33	129.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,464WA@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1519 3-deoxy-D-manno-octulosonic-acid transferase	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
k59_111634_1	745014.OMB55_00006990	4.43e-13	72.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1J9ZU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
k59_135094_1	1121405.dsmv_2374	2.13e-100	300.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MJHX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_123376_2	314230.DSM3645_27598	1.4e-159	459.0	COG3328@1|root,COG3328@2|Bacteria,2J0T4@203682|Planctomycetes	203682|Planctomycetes	L	COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_164467_1	6412.HelroP163959	3.07e-25	112.0	2CZ63@1|root,2S8NK@2759|Eukaryota,39HPZ@33154|Opisthokonta,3CMHR@33208|Metazoa,3DJ85@33213|Bilateria	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas,zf-C2H2,zf-CCHC,zf-H2C2_5
k59_140989_1	349521.HCH_05270	1.35e-09	60.8	COG1887@1|root,COG1887@2|Bacteria,1N67C@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140989_2	1121289.JHVL01000007_gene2805	2.13e-49	176.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,36VW7@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_47038_1	1355374.JARU01000011_gene2252	2.26e-99	301.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2YN6H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalase	katA	GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016999,GO:0017001,GO:0017144,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0051186,GO:0051187,GO:0072593	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
k59_153056_1	706587.Desti_3039	9.15e-34	122.0	COG1013@1|root,COG1013@2|Bacteria,1N0HY@1224|Proteobacteria,42MTM@68525|delta/epsilon subdivisions,2WJS6@28221|Deltaproteobacteria,2MQAS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_78277_1	565655.ECBG_03140	1.41e-50	179.0	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,4AZX7@81852|Enterococcaceae	91061|Bacilli	E	Oligopeptidase F	pepF2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_183784_1	879212.DespoDRAFT_00855	3.2e-48	166.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MJE6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_25776_1	933262.AXAM01000028_gene3342	1.72e-64	209.0	COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,42WFU@68525|delta/epsilon subdivisions,2WS4T@28221|Deltaproteobacteria,2MKX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_160872_1	398767.Glov_2340	2.96e-27	120.0	COG3055@1|root,COG3055@2|Bacteria,1NZ4C@1224|Proteobacteria,430DQ@68525|delta/epsilon subdivisions,2WVRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase C10 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C10
k59_154598_1	867903.ThesuDRAFT_01451	6.04e-15	74.3	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WCD3@538999|Clostridiales incertae sedis	186801|Clostridia	H	Riboflavin biosynthesis protein RibD	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_84221_1	323259.Mhun_1562	2.43e-19	85.1	COG4912@1|root,arCOG05122@2157|Archaea,2XWYV@28890|Euryarchaeota,2N9IE@224756|Methanomicrobia	224756|Methanomicrobia	L	PFAM DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_84221_2	1535422.ND16A_3930	4.41e-17	83.2	COG0823@1|root,COG0823@2|Bacteria,1R8X1@1224|Proteobacteria,1RZDN@1236|Gammaproteobacteria,2Q7XQ@267889|Colwelliaceae	1236|Gammaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_160874_1	1379698.RBG1_1C00001G1061	1.92e-25	106.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_160874_2	290397.Adeh_1557	7.96e-12	61.6	COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k59_7922_2	680198.SCAB_25821	7.84e-32	117.0	2AQME@1|root,31FUG@2|Bacteria,2GJ2E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_113311_1	98439.AJLL01000012_gene2071	3.27e-37	137.0	COG0404@1|root,COG0404@2|Bacteria,1G0GR@1117|Cyanobacteria,1JHWU@1189|Stigonemataceae	1117|Cyanobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_113311_2	572479.Hprae_1602	2.95e-06	53.5	COG2045@1|root,COG2045@2|Bacteria,1V56I@1239|Firmicutes,248U8@186801|Clostridia,3WAYY@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
k59_25789_1	686340.Metal_1537	2.57e-22	95.5	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XE1C@135618|Methylococcales	135618|Methylococcales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_160878_1	1278073.MYSTI_07743	3.02e-27	112.0	COG0845@1|root,COG0845@2|Bacteria,1R50D@1224|Proteobacteria,438S0@68525|delta/epsilon subdivisions,2X3YT@28221|Deltaproteobacteria,2YXMR@29|Myxococcales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_7929_1	1195236.CTER_2368	1.6e-66	213.0	COG0438@1|root,COG0438@2|Bacteria,1U9Z2@1239|Firmicutes,2494K@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_25,TPR_8
k59_183807_2	452637.Oter_2413	3.79e-07	55.1	COG2091@1|root,COG2091@2|Bacteria,46VE0@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_60717_1	7029.ACYPI45590-PA	3.45e-46	176.0	COG2801@1|root,KOG0017@2759|Eukaryota,3ASUJ@33154|Opisthokonta,3C44B@33208|Metazoa,3DK2V@33213|Bilateria	7029.ACYPI45590-PA|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154615_1	1267535.KB906767_gene628	4.99e-23	101.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria,2JHXU@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_66679_1	926550.CLDAP_35030	4.57e-37	138.0	COG0042@1|root,COG0042@2|Bacteria,2G6XB@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_96306_1	1511.CLOST_0290	1.58e-17	87.8	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_137258_1	7029.ACYPI50013-PA	3.42e-06	50.4	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CZSS@33213|Bilateria,4225E@6656|Arthropoda,3SQX6@50557|Insecta,3ECZ1@33342|Paraneoptera	33208|Metazoa	L	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	MULE,RVT_1,gag-asp_proteas,rve
k59_96313_1	400682.PAC_15711609	1.54e-24	111.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3C1BS@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_66692_1	391625.PPSIR1_40415	2.16e-55	189.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_131200_1	1158318.ATXC01000001_gene193	0.000759	41.6	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	vorC	-	1.2.7.3,1.6.5.3	ko:K00176,ko:K00338	ko00020,ko00190,ko00720,ko01100,ko01120,ko01200,map00020,map00190,map00720,map01100,map01120,map01200	M00009,M00011,M00144,M00173,M00620	R01197,R11945	RC00004,RC00061,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4,Fer4_7
k59_131200_2	1232410.KI421421_gene3444	6e-58	191.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,43TQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
k59_13836_1	247639.MGP2080_11663	1.26e-08	56.6	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1J4ZW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_37549_1	1123400.KB904767_gene3412	1.15e-38	132.0	COG3293@1|root,COG3293@2|Bacteria,1N1CW@1224|Proteobacteria,1S8XR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k59_37549_2	321332.CYB_2663	6.55e-42	143.0	COG3385@1|root,COG3385@2|Bacteria,1GA65@1117|Cyanobacteria,1H3BD@1129|Synechococcus	2|Bacteria	L	hmm pf01609	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k59_96334_1	128390.XP_009465681.1	1.03e-10	67.8	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria,48SP6@7711|Chordata,49P6W@7742|Vertebrata,4GVS9@8782|Aves	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_60750_1	101162.XP_007693977.1	2.02e-96	288.0	2C400@1|root,2S2UT@2759|Eukaryota,3ACV6@33154|Opisthokonta,3P8T1@4751|Fungi,3QZWF@4890|Ascomycota	4751|Fungi	L	RNA folding	-	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006310,GO:0006314,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0034337,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1,NUMOD1
k59_96337_1	29730.Gorai.007G165300.1	2.37e-37	140.0	COG0134@1|root,KOG4201@2759|Eukaryota,37PA6@33090|Viridiplantae,3GDJN@35493|Streptophyta	35493|Streptophyta	E	indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_19245_1	644282.Deba_1764	5.21e-18	82.8	28NQ4@1|root,2ZBPU@2|Bacteria,1RCN1@1224|Proteobacteria,42QPC@68525|delta/epsilon subdivisions,2WMVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_178430_1	717231.Flexsi_0440	3.8e-60	196.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_13849_1	13735.ENSPSIP00000001653	5.6e-16	82.4	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_66713_1	1499967.BAYZ01000022_gene254	1.02e-62	206.0	COG4591@1|root,COG4591@2|Bacteria,2NQKW@2323|unclassified Bacteria	2|Bacteria	M	MacB-like periplasmic core domain	VPA0558	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_90069_1	69014.TK1178	2.35e-14	77.0	COG1913@1|root,arCOG00458@2157|Archaea,2XSVV@28890|Euryarchaeota,243DU@183968|Thermococci	183968|Thermococci	S	zinc metalloprotease whose natural substrate is	amzA	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
k59_183858_1	192952.MM_1093	1.56e-11	71.2	arCOG02353@1|root,arCOG05183@1|root,arCOG02353@2157|Archaea,arCOG05183@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HATPase_c,HisKA_2,HisKA_7TM,MCPsignal,PAS,PAS_8,PAS_9,PocR
k59_13854_2	5147.XP_003342374.1	2.34e-20	89.7	2CYQU@1|root,2S4PK@2759|Eukaryota,3A39A@33154|Opisthokonta,3P3IH@4751|Fungi	4751|Fungi	S	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
k59_78367_1	99598.Cal7507_2386	6.7e-24	93.6	COG0713@1|root,COG0713@2|Bacteria,1G6KK@1117|Cyanobacteria,1HNV1@1161|Nostocales	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
k59_13866_1	926569.ANT_26040	2.3e-20	92.8	COG5433@1|root,COG5433@2|Bacteria,2G91G@200795|Chloroflexi	200795|Chloroflexi	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
k59_19268_1	1123371.ATXH01000007_gene575	3.02e-80	254.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2GHHW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_37578_1	466038.KI421440_gene1453	5.11e-114	339.0	COG3842@1|root,COG3842@2|Bacteria,1QU06@1224|Proteobacteria,2TWIE@28211|Alphaproteobacteria,4BTES@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K17324	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	ABC_tran,TOBE_2
k59_101769_1	1121918.ARWE01000001_gene1028	2.41e-21	100.0	COG3941@1|root,COG3941@2|Bacteria,1MZWI@1224|Proteobacteria,42RRK@68525|delta/epsilon subdivisions,2WT71@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mu-like prophage protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13879_1	411471.SUBVAR_07152	3.97e-62	202.0	COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,249T2@186801|Clostridia,3WIMB@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_78393_1	1189620.AJXL01000217_gene3135	0.000292	51.6	COG3385@1|root,COG3385@2|Bacteria,4NIN4@976|Bacteroidetes,1IIBH@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_119602_1	227086.JGI_V11_69065	1.36e-41	154.0	COG2265@1|root,KOG2187@2759|Eukaryota	2759|Eukaryota	J	S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	TRAM,tRNA_U5-meth_tr
k59_38285_1	10224.XP_006825930.1	2.22e-32	138.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_32355_1	683083.C414_000090021	1.43e-40	153.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_164631_1	997353.HMPREF9144_1553	5.68e-72	243.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_105971_1	643562.Daes_3035	4.6e-19	86.7	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2M8ZH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM sulfate adenylyltransferase	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k59_105971_2	1121423.JONT01000001_gene2038	1.83e-77	233.0	COG1146@1|root,COG1146@2|Bacteria,1V59C@1239|Firmicutes,24J64@186801|Clostridia,261U8@186807|Peptococcaceae	186801|Clostridia	C	reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_7,Fer4_9
k59_105971_3	1121428.DESHY_20174___1	8.68e-24	99.4	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,25ZZD@186807|Peptococcaceae	186801|Clostridia	C	reductase alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_17814_1	1487953.JMKF01000054_gene1580	5.5e-07	57.4	COG0642@1|root,COG4191@1|root,COG0642@2|Bacteria,COG4191@2|Bacteria,1G1CF@1117|Cyanobacteria,1HH4T@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,Response_reg
k59_123596_1	1265505.ATUG01000001_gene3096	1.04e-30	113.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42QS2@68525|delta/epsilon subdivisions,2WMXG@28221|Deltaproteobacteria,2MJMH@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_123596_2	1265505.ATUG01000002_gene1392	1.06e-42	161.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MHZP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_23720_1	639030.JHVA01000001_gene2205	1.24e-96	306.0	COG1520@1|root,COG3568@1|root,COG1520@2|Bacteria,COG3568@2|Bacteria,3Y9DD@57723|Acidobacteria,2JK32@204432|Acidobacteriia	204432|Acidobacteriia	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
k59_129445_1	690850.Desaf_1576	9.21e-43	159.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2M8RM@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k59_17826_1	523845.AQXV01000026_gene1469	1.07e-36	144.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
k59_129457_1	679926.Mpet_2732	3.32e-20	94.4	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_82400_1	589865.DaAHT2_1468	1.89e-10	60.5	COG1150@1|root,COG2181@1|root,COG1150@2|Bacteria,COG2181@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2MHSC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
k59_82404_1	7029.ACYPI53951-PA	9.5e-58	197.0	29Q9H@1|root,2RX81@2759|Eukaryota,39ZQJ@33154|Opisthokonta,3BNMR@33208|Metazoa,3D7EF@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_58955_1	742817.HMPREF9449_01390	9.46e-14	72.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FMX8@200643|Bacteroidia,22W1Q@171551|Porphyromonadaceae	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_170472_1	3711.Bra033309.1-P	0.000202	43.5	COG5239@1|root,KOG2338@2759|Eukaryota,37IN7@33090|Viridiplantae,3GF1E@35493|Streptophyta,3HX4U@3699|Brassicales	35493|Streptophyta	K	calcium-binding	-	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0050896	-	ko:K21777	-	-	-	-	ko00000,ko03032,ko03036	-	-	-	EF-hand_8,Exo_endo_phos
k59_64837_1	1150474.JQJI01000015_gene612	7.46e-30	119.0	COG3481@1|root,COG3481@2|Bacteria,2GC74@200918|Thermotogae	200918|Thermotogae	S	nucleic acid binding OB-fold tRNA helicase-type	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
k59_6164_1	945713.IALB_2460	2.08e-15	74.3	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	wbpB	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_6164_2	1321778.HMPREF1982_00469	2.22e-12	68.9	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_11992_1	335543.Sfum_0998	8.4e-36	130.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,2MQI0@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_88342_1	1114964.L485_19120	7.43e-55	181.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TVFK@28211|Alphaproteobacteria,2JZZ5@204457|Sphingomonadales	204457|Sphingomonadales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
k59_88342_2	1121396.KB893096_gene3545	1.33e-09	62.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,42QHS@68525|delta/epsilon subdivisions,2WKSJ@28221|Deltaproteobacteria,2MIVG@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,DUF4388
k59_70719_1	1379698.RBG1_1C00001G0845	3.12e-06	56.2	COG2706@1|root,COG2706@2|Bacteria,2NR81@2323|unclassified Bacteria	2|Bacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,HemolysinCabind,VCBS
k59_35543_1	1125863.JAFN01000001_gene3129	5.23e-74	246.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_64850_2	1236959.BAMT01000004_gene822	2.84e-30	110.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,2KN6T@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
k59_6179_1	303518.XP_005755538.1	9.79e-47	173.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3C0YC@33208|Metazoa,3DH14@33213|Bilateria,48RUJ@7711|Chordata,49N81@7742|Vertebrata,4A97P@7898|Actinopterygii	33208|Metazoa	S	RNA-directed DNA polymerase from mobile element jockey-like	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_11994_1	10224.XP_006819135.1	1.12e-44	164.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_311_1	886293.Sinac_4507	2.72e-55	186.0	COG0330@1|root,COG0330@2|Bacteria,2IY12@203682|Planctomycetes	203682|Planctomycetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_105992_1	1121456.ATVA01000011_gene1345	5.11e-36	140.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_105992_2	765911.Thivi_0648	1.45e-06	59.3	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WWRT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
k59_141187_1	1121918.ARWE01000001_gene2372	3.32e-20	92.4	COG5002@1|root,COG5002@2|Bacteria,1QXTS@1224|Proteobacteria,42QK0@68525|delta/epsilon subdivisions,2WJKM@28221|Deltaproteobacteria,43UJ5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_152852_2	29730.Gorai.001G165500.1	5.46e-09	57.0	2D40E@1|root,2STF1@2759|Eukaryota,381GT@33090|Viridiplantae,3GQJZ@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152852_7	3988.XP_002534719.1	0.0	1196.0	COG3344@1|root,KOG4768@2759|Eukaryota,37KUX@33090|Viridiplantae,3GHBI@35493|Streptophyta,4JTJX@91835|fabids	35493|Streptophyta	A	NADH dehydrogenase (quinone) activity	matR	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2
k59_152852_8	4081.Solyc11g056320.1.1	4.33e-42	140.0	2E3CF@1|root,2SAFZ@2759|Eukaryota,37X5G@33090|Viridiplantae,3GM6T@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123677_1	797114.C475_01966	1.92e-40	150.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUW2@28890|Euryarchaeota,23UD5@183963|Halobacteria	183963|Halobacteria	M	COG0668 Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_17873_1	398580.Dshi_3007	2.08e-56	200.0	COG0383@1|root,COG0383@2|Bacteria,1R3Q8@1224|Proteobacteria,2TTPY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Alpha mannosidase, middle domain	mngB	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
k59_53125_1	1219049.SP5_045_00050	1.21e-30	122.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,2K00X@204457|Sphingomonadales	204457|Sphingomonadales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_323_1	7668.SPU_026086-tr	4.38e-33	140.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta	33154|Opisthokonta	I	queuine tRNA-ribosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_135328_1	102107.XP_008223402.1	1.09e-07	59.3	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta,4JM10@91835|fabids	35493|Streptophyta	H	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVP_2,RVT_1,Retrotrans_gag,rve,zf-CCHC
k59_111794_1	31234.CRE14091	1.2e-67	244.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_6228_1	449447.MAE_30320	7.82e-73	235.0	COG5421@1|root,COG5421@2|Bacteria,1G3YW@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_182249_1	1500281.JQKZ01000003_gene1718	8.91e-08	62.8	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,1I01F@117743|Flavobacteriia,3ZUGQ@59732|Chryseobacterium	976|Bacteroidetes	S	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_141197_1	1134413.ANNK01000091_gene16	4.7e-16	82.8	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,1ZAWH@1386|Bacillus	91061|Bacilli	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	spsI	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_141197_2	909663.KI867150_gene943	1.26e-50	172.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MQ9B@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_141199_1	448385.sce6414	7.49e-39	145.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_70768_1	7897.ENSLACP00000003121	1.12e-31	129.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria,48QHZ@7711|Chordata,497ZU@7742|Vertebrata	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_17889_1	7668.SPU_021180-tr	2.34e-38	155.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,RVT_1
k59_18503_1	694431.DESACE_07195	2.48e-27	103.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2789,iNRG857_1313.NRG857_06920	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_18503_2	760568.Desku_3485	7.89e-55	172.0	COG2920@1|root,COG2920@2|Bacteria,1V6WF@1239|Firmicutes,24JRH@186801|Clostridia,262IF@186807|Peptococcaceae	186801|Clostridia	P	sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_35024_40	1075090.GOAMR_69_00780	4.32e-10	58.2	COG3609@1|root,COG3609@2|Bacteria	2|Bacteria	K	positive regulation of growth	parD1	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
k59_35024_49	1291050.JAGE01000001_gene1622	9.53e-113	381.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae	186801|Clostridia	KL	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
k59_35024_69	1131813.AQVT01000001_gene3270	6.56e-90	294.0	COG4676@1|root,COG4676@2|Bacteria,1NATM@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105433_1	398512.JQKC01000004_gene5231	0.000799	47.8	COG0526@1|root,COG0652@1|root,COG0526@2|Bacteria,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3WNAW@541000|Ruminococcaceae	186801|Clostridia	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Cu_amine_oxidN1,Pro_isomerase
k59_52195_1	6087.XP_004209490.1	2.48e-14	78.2	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa	33208|Metazoa	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_187692_1	402777.KB235898_gene4943	2.46e-08	61.2	COG3210@1|root,COG3266@1|root,COG4995@1|root,COG5624@1|root,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4995@2|Bacteria,COG5624@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act
k59_158280_2	1355374.JARU01000001_gene566	3.69e-30	119.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RCNJ@1224|Proteobacteria,43AF2@68525|delta/epsilon subdivisions,2YT2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	cadF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
k59_35042_1	1220583.GOACH_04_05320	9.59e-11	69.7	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4GECQ@85026|Gordoniaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_158304_1	945713.IALB_1150	7.94e-62	207.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01704,ko:K01705	ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_158304_2	1047013.AQSP01000140_gene2449	3.07e-11	61.6	COG1418@1|root,COG1418@2|Bacteria,2NPXI@2323|unclassified Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
k59_52270_1	1122983.BAJY01000002_gene323	3.77e-44	157.0	COG3177@1|root,COG3177@2|Bacteria,4NFBY@976|Bacteroidetes	976|Bacteroidetes	K	Pfam Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_DeoR
k59_52281_1	886293.Sinac_4362	5.26e-72	228.0	COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes	203682|Planctomycetes	P	COG0798 Arsenite efflux pump ACR3 and related	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_23268_1	1502851.FG93_05995	3.21e-36	137.0	COG1171@1|root,COG1171@2|Bacteria,1QVNS@1224|Proteobacteria,2TUHW@28211|Alphaproteobacteria,3K6FK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Diaminopropionate ammonia-lyase	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
k59_35084_1	903818.KI912269_gene180	7.14e-26	107.0	28K30@1|root,3359X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_116839_1	85643.Tmz1t_3892	2.14e-08	64.7	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VZHX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_35099_1	4081.Solyc11g062200.1.1	2.78e-100	321.0	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae,3GG2K@35493|Streptophyta,44UC5@71274|asterids	35493|Streptophyta	L	Mitochondrial protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve,zf-CCHC
k59_35104_1	573063.Metin_1123	1.64e-06	49.7	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota,23R2D@183939|Methanococci	183939|Methanococci	S	PFAM Roadblock LC7 family protein	-	GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
k59_35104_2	1313304.CALK_0312	2.2e-74	238.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
k59_158375_1	1218108.KB908308_gene199	4.49e-32	130.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_116857_1	448385.sce1086	4.88e-132	399.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2YW51@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
k59_116858_1	335543.Sfum_1227	6.89e-62	204.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MQWA@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_52354_1	555088.DealDRAFT_0254	7.8e-35	133.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,248TA@186801|Clostridia	186801|Clostridia	CP	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_105536_1	640511.BC1002_6823	1.34e-36	126.0	COG2963@1|root,COG2963@2|Bacteria,1N8Y3@1224|Proteobacteria,2VY0M@28216|Betaproteobacteria,1KAA0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_176100_1	1122176.KB903565_gene3244	1.54e-05	51.6	COG1629@1|root,COG1629@2|Bacteria,4PPDE@976|Bacteroidetes,1IYC1@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_158401_1	909663.KI867150_gene2278	2.88e-19	81.3	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k59_158401_2	1223542.GM1_025_00610	3.71e-15	77.4	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4GD6W@85026|Gordoniaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_105550_1	1122185.N792_04450	2.69e-31	126.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X5ET@135614|Xanthomonadales	135614|Xanthomonadales	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_35153_1	706587.Desti_4421	3.72e-118	354.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MQ8K@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM MgsA AAA ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_52405_1	551789.ATVJ01000001_gene2200	1.85e-18	84.3	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,43W91@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	NAD(P)H-binding	-	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_52405_2	1210884.HG799464_gene10720	6.87e-27	103.0	COG1898@1|root,COG1898@2|Bacteria,2J35V@203682|Planctomycetes	203682|Planctomycetes	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	dTDP_sugar_isom
k59_116895_2	1385521.N803_15025	2.94e-10	60.8	COG3682@1|root,COG3682@2|Bacteria,2IIIT@201174|Actinobacteria,4FHMJ@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	blaI	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_158462_1	879212.DespoDRAFT_02520	3.2e-110	332.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_116919_1	1521187.JPIM01000087_gene3320	3.22e-38	144.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi,3750E@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
k59_35200_1	986075.CathTA2_2990	1.77e-61	202.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli	91061|Bacilli	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_17892_1	906968.Trebr_0705	3.42e-08	58.5	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,2J6UE@203691|Spirochaetes	203691|Spirochaetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
k59_147069_1	1047013.AQSP01000142_gene189	2.7e-53	182.0	COG3051@1|root,COG3051@2|Bacteria,2NP8D@2323|unclassified Bacteria	2|Bacteria	C	Citrate lyase, alpha subunit (CitF)	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
k59_147069_2	439481.Aboo_1327	2.43e-14	74.7	COG1514@1|root,arCOG01736@2157|Archaea,2XZ2M@28890|Euryarchaeota,3F2TR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k59_176491_1	31234.CRE23042	2.45e-47	171.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_116558_1	56780.SYN_02628	2.76e-63	211.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Glycosyl transferase, family 20	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
k59_5845_2	632518.Calow_2066	3.64e-06	47.8	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia,42F76@68295|Thermoanaerobacterales	186801|Clostridia	N	Flagellar basal body rod protein	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_40954_1	1121889.AUDM01000011_gene2768	1.02e-81	264.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
k59_93750_1	1096756.ATKN01000022_gene1622	1.15e-20	98.6	arCOG08054@1|root,2Z8AD@2|Bacteria,2GKIT@201174|Actinobacteria,1WAKQ@1268|Micrococcaceae	201174|Actinobacteria	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	-	-	-	-	-	-	-	-	-	-	-	Cthe_2159
k59_140598_1	1192034.CAP_1865	6.49e-95	296.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,43CJE@68525|delta/epsilon subdivisions,2X7TT@28221|Deltaproteobacteria,2Z3N4@29|Myxococcales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_76135_1	1047013.AQSP01000134_gene1338	1.87e-61	206.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k59_134882_1	742725.HMPREF9450_01487	0.000294	42.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,2FPHH@200643|Bacteroidia,22U1K@171550|Rikenellaceae	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_134882_2	1379698.RBG1_1C00001G1489	6.21e-61	208.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_123263_1	1121405.dsmv_1974	1.29e-102	330.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MHRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_87991_1	1047013.AQSP01000114_gene684	2.08e-74	244.0	COG1629@1|root,COG2304@1|root,COG1629@2|Bacteria,COG2304@2|Bacteria,2NQ3W@2323|unclassified Bacteria	2|Bacteria	P	von Willebrand factor type A domain	yfbK	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,Plug,VWA,vWF_A
k59_93763_1	448385.sce2882	9.23e-116	344.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,2YY78@29|Myxococcales	28221|Deltaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_46776_1	1089447.RHAA1_09491	1.48e-45	164.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1Y6QT@135625|Pasteurellales	135625|Pasteurellales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_123268_1	584708.Apau_2405	3.35e-52	171.0	COG2110@1|root,COG2110@2|Bacteria,3TB5Z@508458|Synergistetes	508458|Synergistetes	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_46779_1	1449126.JQKL01000006_gene809	1.06e-10	68.6	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_40983_1	935948.KE386494_gene373	2.02e-102	312.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,42FJB@68295|Thermoanaerobacterales	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_40988_1	6087.XP_004209230.1	6.18e-06	50.4	2CQK3@1|root,2S458@2759|Eukaryota,3A7MN@33154|Opisthokonta,3BSRK@33208|Metazoa	33208|Metazoa	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4,THAP
k59_158037_1	96561.Dole_1813	1.69e-70	224.0	COG1373@1|root,COG1373@2|Bacteria,1NQGE@1224|Proteobacteria,42R19@68525|delta/epsilon subdivisions,2WMNW@28221|Deltaproteobacteria,2MMR8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
k59_105253_1	990073.ATHU01000001_gene849	1.94e-66	215.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42PR5@68525|delta/epsilon subdivisions,2YSZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_140640_1	1167006.UWK_01018	1.24e-30	124.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MPI2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
k59_46800_1	161156.JQKW01000014_gene214	4.72e-14	68.6	arCOG10385@1|root,32SEM@2|Bacteria,2GHUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46800_2	335543.Sfum_1149	4.56e-111	328.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MQSD@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k59_46801_1	1463887.KL590085_gene537	3.06e-10	65.9	COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,VCBS
k59_41015_1	1519464.HY22_14450	6.11e-40	150.0	COG0205@1|root,COG2905@1|root,COG0205@2|Bacteria,COG2905@2|Bacteria,1FERT@1090|Chlorobi	1090|Chlorobi	GT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PFK,cNMP_binding
k59_105270_1	7029.ACYPI43222-PA	7.43e-12	72.4	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa,3DKI7@33213|Bilateria	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_11610_1	439235.Dalk_5087	4.69e-148	427.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_93825_1	665952.HMPREF1015_02296	3.38e-16	82.8	COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4HEAJ@91061|Bacilli,1ZR9S@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
k59_88037_1	10224.XP_006819133.1	6.19e-61	217.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_175771_2	398720.MED217_00935	9.55e-23	93.2	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia,2XIK9@283735|Leeuwenhoekiella	976|Bacteroidetes	K	Transcription elongation factor, N-terminal	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_93844_1	340177.Cag_1220	2.5e-28	112.0	COG0703@1|root,COG0703@2|Bacteria,1FDXE@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_93844_2	1123227.KB899333_gene526	2.18e-38	147.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2JP8I@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
k59_46842_1	1121405.dsmv_3691	4.6e-73	231.0	COG3547@1|root,COG3547@2|Bacteria,1NP2U@1224|Proteobacteria,43A5Q@68525|delta/epsilon subdivisions,2X2AM@28221|Deltaproteobacteria,2MPDW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46843_1	1121928.AUHE01000010_gene2681	5.67e-07	52.4	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4GD47@85026|Gordoniaceae	201174|Actinobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_46843_2	118163.Ple7327_1304	0.000339	47.4	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3290@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,3VJG3@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_3,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
k59_23043_1	1265505.ATUG01000002_gene1874	2.6e-70	227.0	COG4191@1|root,COG4191@2|Bacteria,1R6WR@1224|Proteobacteria,42PFK@68525|delta/epsilon subdivisions,2WJSP@28221|Deltaproteobacteria,2MHRP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_93858_1	1123035.ARLA01000028_gene2514	4.54e-06	57.4	COG3209@1|root,COG3209@2|Bacteria,4NW4C@976|Bacteroidetes,1I5Z5@117743|Flavobacteriia,4C4D8@83612|Psychroflexus	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_52051_1	702113.PP1Y_Mpl2050	1.94e-12	73.6	COG1474@1|root,COG3206@1|root,COG1474@2|Bacteria,COG3206@2|Bacteria,1R6DE@1224|Proteobacteria	1224|Proteobacteria	LO	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_23062_1	1242864.D187_007363	3.56e-45	164.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111546_1	760117.JN27_10735	1.6e-15	80.9	2DBPG@1|root,2ZA96@2|Bacteria,1QVNF@1224|Proteobacteria,2VP5D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
k59_158134_2	1033743.CAES01000036_gene1228	7.22e-37	140.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,26RNW@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_47692_1	6087.XP_002160733.2	1.36e-127	409.0	COG1131@1|root,KOG0061@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	-	-	ko:K05681	ko01523,ko02010,ko04976,map01523,map02010,map04976	-	-	-	ko00000,ko00001,ko02000,ko04090,ko04147	3.A.1.204	-	-	ABC2_membrane,ABC_tran
k59_182673_1	1206732.BAGD01000046_gene1590	1.75e-31	120.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4FUJZ@85025|Nocardiaceae	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
k59_30132_1	3988.XP_002534684.1	6.07e-75	230.0	2E43Y@1|root,2SB2A@2759|Eukaryota,37X2E@33090|Viridiplantae,3GKUQ@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_30132_2	59689.fgenesh1_pm.C_scaffold_3002392	2.89e-86	267.0	COG1008@1|root,KOG4845@2759|Eukaryota,37TUR@33090|Viridiplantae,3GI7Y@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_30132_3	3880.AES58516	2.6e-09	60.1	COG1008@1|root,KOG4845@2759|Eukaryota,37TUR@33090|Viridiplantae,3GI7Y@35493|Streptophyta,4JUXR@91835|fabids	35493|Streptophyta	C	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_159382_7	871585.BDGL_000495	6.5e-18	77.4	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,3NQ0R@468|Moraxellaceae	1236|Gammaproteobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_159382_19	716928.AJQT01000109_gene1217	1.02e-44	150.0	2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94800_1	1047013.AQSP01000114_gene696	1.25e-08	58.9	COG5276@1|root,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,LVIVD
k59_883_1	7029.ACYPI38677-PA	8.42e-63	219.0	2BXPG@1|root,2S2FM@2759|Eukaryota,3A3WK@33154|Opisthokonta,3BRCR@33208|Metazoa,3D8NG@33213|Bilateria,4225N@6656|Arthropoda,3SQ9G@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_177070_1	760142.Hipma_0827	2.41e-45	162.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_887_1	7029.ACYPI52783-PA	9.56e-15	75.1	28MXD@1|root,2QUFX@2759|Eukaryota,38TCJ@33154|Opisthokonta,3BIIF@33208|Metazoa,3D2PH@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_53807_1	1231241.Mc24_03348	8e-47	160.0	COG0745@1|root,COG0745@2|Bacteria,2GCK6@200918|Thermotogae	200918|Thermotogae	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_165524_1	96561.Dole_2062	9.92e-35	127.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WIWA@28221|Deltaproteobacteria,2MIT5@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_165524_2	313628.LNTAR_05091	2.44e-10	60.5	COG1492@1|root,COG1492@2|Bacteria	2|Bacteria	H	cobalamin biosynthetic process	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_03184	AAA_26,Aminotran_1_2,CbiA,GATase_3
k59_83086_1	28072.Nos7524_1372	1.08e-09	65.5	COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G1WI@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin,Calx-beta,PPC
k59_118313_1	7897.ENSLACP00000006482	9.81e-20	92.8	2CYKY@1|root,2S52Z@2759|Eukaryota,39VMN@33154|Opisthokonta,3CNG8@33208|Metazoa,3E4M0@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT
k59_89013_1	1379698.RBG1_1C00001G1092	7.94e-44	168.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
k59_30291_1	7070.TC011483-PA	1.58e-14	83.6	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_130085_1	880073.Calab_0123	1.54e-09	59.3	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_legB,NB-ARC,TIR_2,WD40
k59_141820_1	113355.CM001775_gene3188	4.34e-30	107.0	2DNQR@1|root,32YKU@2|Bacteria,1G9K3@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141820_2	1123230.ARQJ01000001_gene1096	2.65e-15	71.2	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4GZG2@90964|Staphylococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_59614_2	861299.J421_1827	7.72e-19	88.6	COG0515@1|root,COG0515@2|Bacteria,1ZUHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
k59_30297_1	243231.GSU0613	3.86e-10	64.3	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,43SZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_911_1	1379698.RBG1_1C00001G0733	3.87e-36	142.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_59615_1	449447.MAE_12400	8.86e-36	141.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	bhp	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	B_lectin,Big_3_2,Big_5,Calx-beta,DUF4347,HemolysinCabind
k59_30302_1	290317.Cpha266_1674	1.06e-94	287.0	COG0462@1|root,COG0462@2|Bacteria,1FD7M@1090|Chlorobi	1090|Chlorobi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_47889_2	767817.Desgi_4179	1.33e-60	205.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,1TQM4@1239|Firmicutes,2495Q@186801|Clostridia,2619Z@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
k59_182836_1	742740.HMPREF9474_02505	3.03e-26	111.0	28JNG@1|root,2Z9ES@2|Bacteria,1V9K6@1239|Firmicutes,24H64@186801|Clostridia,2226N@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_71346_1	525257.HMPREF0204_11070	3.3e-57	199.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,1HXJI@117743|Flavobacteriia,3ZNJT@59732|Chryseobacterium	976|Bacteroidetes	P	Putative metal-binding domain of cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_71348_1	6412.HelroP163959	6.99e-14	78.6	2CZ63@1|root,2S8NK@2759|Eukaryota,39HPZ@33154|Opisthokonta,3CMHR@33208|Metazoa,3DJ85@33213|Bilateria	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas,zf-C2H2,zf-CCHC,zf-H2C2_5
k59_118376_1	9606.ENSP00000423550	3.95e-47	171.0	COG0553@1|root,KOG0387@2759|Eukaryota,38BYH@33154|Opisthokonta,3BB1V@33208|Metazoa,3CTYM@33213|Bilateria,484BU@7711|Chordata,48XVI@7742|Vertebrata,3JCN1@40674|Mammalia,35IEU@314146|Euarchontoglires,4MBCW@9443|Primates,4N20K@9604|Hominidae	33208|Metazoa	K	transcription elongation from RNA polymerase I promoter	ERCC6	GO:0000166,GO:0001932,GO:0001934,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006284,GO:0006289,GO:0006351,GO:0006355,GO:0006366,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008022,GO:0008023,GO:0008047,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019207,GO:0019209,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019887,GO:0019899,GO:0030234,GO:0030295,GO:0030296,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032147,GO:0032268,GO:0032270,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032784,GO:0032786,GO:0032991,GO:0033554,GO:0033674,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040029,GO:0042325,GO:0042327,GO:0042623,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045815,GO:0045859,GO:0045860,GO:0045893,GO:0045935,GO:0045937,GO:0046483,GO:0047485,GO:0048518,GO:0048522,GO:0050730,GO:0050731,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051338,GO:0051347,GO:0051716,GO:0060255,GO:0061097,GO:0061098,GO:0065007,GO:0065009,GO:0070013,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0098772,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K10841	ko03420,map03420	-	-	-	ko00000,ko00001,ko03036,ko03400	-	-	-	Helicase_C,SNF2_N
k59_938_1	368407.Memar_0689	0.000766	44.3	COG1541@1|root,arCOG02624@2157|Archaea,2XW5Z@28890|Euryarchaeota	28890|Euryarchaeota	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_939_1	156889.Mmc1_2410	1.93e-69	225.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_47912_1	240292.Ava_4702	1.35e-20	93.2	COG0745@1|root,COG4585@1|root,COG0745@2|Bacteria,COG4585@2|Bacteria,1GQQ8@1117|Cyanobacteria,1HJPF@1161|Nostocales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_47912_2	1000565.METUNv1_00467	1.51e-09	60.8	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2VJ2N@28216|Betaproteobacteria,2KVGG@206389|Rhodocyclales	206389|Rhodocyclales	S	synthesis repressor, PhaR	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
k59_177146_1	6500.XP_005107990.1	9.22e-27	110.0	2EMJ6@1|root,2SR73@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRE_C2HC,WW
k59_171414_1	273371.XP_003866674.1	1.96e-07	55.5	COG0406@1|root,KOG0234@2759|Eukaryota,3A7E1@33154|Opisthokonta,3P6IB@4751|Fungi,3QYEM@4890|Ascomycota,3RVA5@4891|Saccharomycetes,47C70@766764|Debaryomycetaceae	4751|Fungi	G	6-phosphofructo-2-kinase	-	-	2.7.1.105	ko:K00900	ko00051,map00051	-	R02732	RC00002,RC00152	ko00000,ko00001,ko01000	-	-	-	6PF2K
k59_65631_1	7091.BGIBMGA006564-TA	2.66e-25	103.0	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89541_1	996637.SGM_1941	3.17e-21	93.2	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria	201174|Actinobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_89541_2	529818.AMSG_06857T0	4.54e-12	68.6	COG0304@1|root,KOG1394@2759|Eukaryota	2759|Eukaryota	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	OXSM	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0016043,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046459,GO:0046483,GO:0051186,GO:0051790,GO:0051791,GO:0051792,GO:0055086,GO:0061024,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576	2.3.1.179	ko:K09458,ko:K17255	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_54451_1	7070.TC012970-PA	7.14e-93	299.0	28R8K@1|root,2QXXP@2759|Eukaryota,39Y7E@33154|Opisthokonta,3BNIR@33208|Metazoa,3D4BA@33213|Bilateria,41YTH@6656|Arthropoda,3SM2H@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_107245_1	1255043.TVNIR_1400	1.02e-27	118.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RY7B@1236|Gammaproteobacteria,1X2AS@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	NHL,RHS_repeat
k59_158907_4	1161931.J7FA60_9CAUD	1.83e-144	449.0	4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses  no RNA stage,4QPTT@28883|Caudovirales,4QJD7@10662|Myoviridae	10662|Myoviridae	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_158907_7	744980.TRICHSKD4_2275	1.03e-21	98.2	COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,2UE4W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolases of HD superfamily	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	-
k59_123806_1	981085.XP_010089869.1	2.45e-104	317.0	28JG1@1|root,2QRV6@2759|Eukaryota,37HEX@33090|Viridiplantae,3GE8P@35493|Streptophyta	35493|Streptophyta	S	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0010207,GO:0010287,GO:0015979,GO:0016020,GO:0016043,GO:0019684,GO:0022607,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0065003,GO:0071840	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_454_3	3880.AES58520	2.93e-09	57.8	2EY1V@1|root,2SZM9@2759|Eukaryota,382EN@33090|Viridiplantae,3GMWC@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70885_1	313606.M23134_05227	3.45e-30	128.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
k59_176583_1	635013.TherJR_0655	2.88e-36	138.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
k59_41524_1	1519464.HY22_13440	2.37e-58	186.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
k59_47366_1	246197.MXAN_6293	3.76e-63	207.0	COG5659@1|root,COG5659@2|Bacteria,1MXSV@1224|Proteobacteria,42UR2@68525|delta/epsilon subdivisions,2WQER@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_76777_1	1046627.BZARG_919	2.22e-19	94.4	COG1566@1|root,COG1566@2|Bacteria,4NF6F@976|Bacteroidetes,1HZS5@117743|Flavobacteriia	976|Bacteroidetes	V	COG0845 Membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,OEP
k59_18001_1	7668.SPU_002135-tr	1.76e-57	195.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3BSEH@33208|Metazoa,3D91U@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_47384_1	1123274.KB899407_gene138	5.53e-95	293.0	COG2309@1|root,COG2309@2|Bacteria,2J6N5@203691|Spirochaetes	203691|Spirochaetes	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k59_82585_1	879212.DespoDRAFT_02040	4.76e-35	131.0	COG0484@1|root,COG0705@1|root,COG0484@2|Bacteria,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2MI6P@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
k59_82585_2	526222.Desal_0725	3.24e-10	59.7	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2M8C0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	malic protein domain protein	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
k59_135477_1	6412.HelroP172394	7.74e-44	158.0	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa,3E5DG@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_29830_1	32024.JMTI01000006_gene63	1.75e-45	157.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2YM8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_472_1	926569.ANT_17280	2.22e-34	127.0	COG1028@1|root,COG1028@2|Bacteria,2G8P1@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_135479_1	1121468.AUBR01000030_gene1226	2.72e-77	244.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_135481_1	90675.XP_010451516.1	6.74e-43	159.0	COG2801@1|root,KOG0017@2759|Eukaryota,37SNQ@33090|Viridiplantae,3GHRQ@35493|Streptophyta,3HVU8@3699|Brassicales	35493|Streptophyta	L	GAG-pre-integrase domain	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,gag_pre-integrs,rve,zf-CCHC
k59_18010_1	459349.CLOAM1867	3.97e-05	45.4	COG4412@1|root,COG4412@2|Bacteria,2NRKS@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_4,CHU_C,CarboxypepD_reg,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,MAM,Peptidase_C25,Peptidase_M6,Peptidase_S8,Propeptide_C25,SLH,W_rich_C,fn3
k59_18010_2	1191523.MROS_2237	7.03e-21	98.2	COG0823@1|root,COG4733@1|root,COG0823@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201,ko:K13669	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000,ko01003	-	GH30,GT87	-	CBM_6,GT87,PD40
k59_100228_1	1121406.JAEX01000001_gene321	6.17e-35	130.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2M85A@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_100228_2	1283299.AUKG01000001_gene1869	3.24e-17	86.7	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GK3B@201174|Actinobacteria,4CPJJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_6360_1	1410624.JNKK01000044_gene564	7.55e-23	101.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,27IQB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
k59_176596_1	7029.ACYPI007702-PA	5.76e-73	255.0	COG2801@1|root,KOG0017@2759|Eukaryota,3ABZJ@33154|Opisthokonta,3CPEU@33208|Metazoa,3E5JW@33213|Bilateria,42AMJ@6656|Arthropoda	7029.ACYPI007702-PA|-	L	Domain of unknown function (DUF4806)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12125_2	706587.Desti_5326	8.26e-36	134.0	COG3852@1|root,COG3852@2|Bacteria,1R1JU@1224|Proteobacteria,43DA4@68525|delta/epsilon subdivisions,2X8GR@28221|Deltaproteobacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	regM	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_70905_1	653733.Selin_2484	1.35e-39	145.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_53325_1	1380380.JIAX01000008_gene2083	1.41e-87	287.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
k59_158948_1	404589.Anae109_4384	3.95e-50	174.0	COG0006@1|root,COG0006@2|Bacteria,1NS4T@1224|Proteobacteria,439D0@68525|delta/epsilon subdivisions,2X4MK@28221|Deltaproteobacteria,2Z068@29|Myxococcales	28221|Deltaproteobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
k59_65049_1	8049.ENSGMOP00000009375	2.41e-76	249.0	28TCR@1|root,2R035@2759|Eukaryota,39TI0@33154|Opisthokonta,3BAFE@33208|Metazoa,3D17K@33213|Bilateria,487FB@7711|Chordata,491IP@7742|Vertebrata,4A56D@7898|Actinopterygii	33208|Metazoa	S	kiaa1586	KIAA1586	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_141365_1	1429851.X548_04955	4.76e-44	155.0	COG4709@1|root,COG4709@2|Bacteria,1NX5K@1224|Proteobacteria,1SPS6@1236|Gammaproteobacteria,1X34I@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
k59_123828_1	1408436.JHXY01000016_gene1046	2.38e-06	53.5	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,25VSN@186806|Eubacteriaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_158970_1	3880.AES88228	4.74e-23	97.4	COG0052@1|root,COG0356@1|root,COG0636@1|root,KOG0232@2759|Eukaryota,KOG0832@2759|Eukaryota,KOG4665@2759|Eukaryota,37S1B@33090|Viridiplantae,3GHIA@35493|Streptophyta	35493|Streptophyta	J	ribosomal protein S2	rps2	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_158970_2	218851.Aquca_038_00147.1	1.59e-43	142.0	COG0636@1|root,KOG0232@2759|Eukaryota,37W5A@33090|Viridiplantae,3GK4X@35493|Streptophyta	35493|Streptophyta	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_12162_1	1385510.N781_11790	9.55e-12	71.2	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,2Y8XH@289201|Pontibacillus	91061|Bacilli	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_117844_1	29540.C481_13554	3.69e-60	201.0	COG1012@1|root,arCOG01252@2157|Archaea,2XT1Y@28890|Euryarchaeota,23RYR@183963|Halobacteria	183963|Halobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_94339_1	497964.CfE428DRAFT_6305	4.29e-59	204.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia	74201|Verrucomicrobia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k59_82613_1	400682.PAC_15705889	8.77e-20	96.7	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3C0YC@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_135500_2	1379698.RBG1_1C00001G0565	2.46e-30	116.0	COG2834@1|root,COG2834@2|Bacteria,2NQJ8@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,DUF4367,LolA_like
k59_170720_1	997830.HMPREF1124_0560	3.59e-50	174.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,43F4M@68892|Streptococcus infantis	91061|Bacilli	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_182396_1	1437824.BN940_13546	1.66e-72	239.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,3T2RD@506|Alcaligenaceae	28216|Betaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	zraR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_182396_2	1379698.RBG1_1C00001G1865	2.61e-37	144.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_82623_1	207954.MED92_01304	2.56e-42	155.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1XIZU@135619|Oceanospirillales	135619|Oceanospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_6395_1	1120999.JONM01000007_gene1877	1.01e-45	164.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,2VIT3@28216|Betaproteobacteria,2KSS3@206351|Neisseriales	206351|Neisseriales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
k59_111960_1	525367.HMPREF0556_12233	4.11e-24	105.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,26IU3@186820|Listeriaceae	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08420	GlutR_N,GlutR_dimer,Shikimate_DH
k59_76822_1	1379698.RBG1_1C00001G1787	2.57e-21	97.8	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
k59_89171_2	1123371.ATXH01000040_gene1169	2.33e-23	101.0	COG1022@1|root,COG1022@2|Bacteria,2GIQW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_141940_8	3847.GLYMA08G41240.2	0.000201	44.7	2CKHQ@1|root,2S5E8@2759|Eukaryota,37WKE@33090|Viridiplantae,3GKNN@35493|Streptophyta,4JVAD@91835|fabids	35493|Streptophyta	S	Mitovirus RNA-dependent RNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Mitovir_RNA_pol
k59_50474_13	72664.XP_006409508.1	6.09e-137	388.0	COG0852@1|root,KOG1713@2759|Eukaryota,37SXR@33090|Viridiplantae,3GGAU@35493|Streptophyta,3HWPR@3699|Brassicales	35493|Streptophyta	C	Belongs to the complex I 30 kDa subunit family	nad9	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3,1.6.99.3	ko:K03936	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_30kDa
k59_50474_19	3988.XP_002535295.1	3.07e-14	70.1	2CZGP@1|root,2SAB4@2759|Eukaryota,37WZW@33090|Viridiplantae,3GKSR@35493|Streptophyta	35493|Streptophyta	-	-	-	-	1.6.5.3	ko:K03878	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_50474_20	3988.XP_002540128.1	2.19e-53	171.0	COG1005@1|root,KOG4770@2759|Eukaryota,37XCB@33090|Viridiplantae,3GMDS@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
k59_115008_1	696281.Desru_0598	1.58e-46	172.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,263ZP@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_62669_1	1499967.BAYZ01000017_gene6261	2.64e-35	133.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
k59_98623_1	1068978.AMETH_0337	6.02e-17	84.3	COG4870@1|root,COG4870@2|Bacteria,2ICZT@201174|Actinobacteria	201174|Actinobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
k59_174124_1	742733.HMPREF9469_03286	2.14e-51	179.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,21XPS@1506553|Lachnoclostridium	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k59_186030_1	7918.ENSLOCP00000019782	4.55e-46	179.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,487I3@7711|Chordata,4962T@7742|Vertebrata,4A7TP@7898|Actinopterygii	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_21291_1	1379698.RBG1_1C00001G0736	4.15e-122	361.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_163002_1	6087.XP_004212272.1	2.19e-27	118.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F2S@33154|Opisthokonta,3BI3C@33208|Metazoa	33208|Metazoa	L	Gypsy retrotransposon integrase-like protein	GIN1	-	-	-	-	-	-	-	-	-	-	-	SCAN,THAP,rve,zf-CCHC,zf-H2C2
k59_80591_1	867845.KI911784_gene1685	1.49e-42	152.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_80592_1	552811.Dehly_0649	2.06e-90	288.0	COG3039@1|root,COG4198@1|root,COG3039@2|Bacteria,COG4198@2|Bacteria,2G9US@200795|Chloroflexi,34D8F@301297|Dehalococcoidia	2|Bacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF1015,DUF772
k59_151114_1	933262.AXAM01000027_gene2104	5.66e-130	378.0	COG2391@1|root,COG2391@2|Bacteria,1NCH7@1224|Proteobacteria,42NKG@68525|delta/epsilon subdivisions,2WJFC@28221|Deltaproteobacteria,2MHNY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_168899_1	7918.ENSLOCP00000022184	0.000309	45.8	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3B9WN@33208|Metazoa,3D1S8@33213|Bilateria,48C1W@7711|Chordata,49N8J@7742|Vertebrata,4A94B@7898|Actinopterygii	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_86397_1	997296.PB1_14084	7.17e-56	189.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_10010_1	8479.XP_005305226.1	1.31e-123	369.0	28HC0@1|root,2QPQD@2759|Eukaryota,39S4C@33154|Opisthokonta,3BMKF@33208|Metazoa,3D63M@33213|Bilateria,48BPK@7711|Chordata,495JJ@7742|Vertebrata,4CMFM@8459|Testudines	33208|Metazoa	S	ZnF_TTF	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_45173_1	56780.SYN_00411	4.07e-24	100.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2MQXR@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_45173_2	1278306.KB906913_gene1007	3.31e-11	62.8	COG1120@1|root,COG1120@2|Bacteria,379B8@32066|Fusobacteria	32066|Fusobacteria	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_180616_1	880072.Desac_2201	4.48e-10	67.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,42TY9@68525|delta/epsilon subdivisions,2WQH3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
k59_33536_1	1379698.RBG1_1C00001G0428	5.01e-25	106.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS
k59_163024_2	1379698.RBG1_1C00001G0457	1.14e-16	78.6	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	GlpG	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	Rhomboid
k59_62741_1	404380.Gbem_3999	3.02e-11	71.2	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
k59_127659_2	1122217.KB899594_gene1328	1.53e-14	72.4	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4H1XK@909932|Negativicutes	909932|Negativicutes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_45202_1	1379698.RBG1_1C00001G1089	1.01e-10	63.5	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5,PAS,PAS_3,PAS_9,Response_reg
k59_16207_1	102107.XP_008224000.1	1.21e-291	867.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta,4JREA@91835|fabids	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	ycf1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	-	-	-	-	-	-	-	-	-	Ycf1
k59_103764_1	6334.EFV50733	2.41e-85	291.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,DUF1758,DUF1759,Peptidase_A17,RVT_1,rve
k59_33573_1	1122919.KB905561_gene1546	7.87e-76	249.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26QQ1@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_10060_1	7029.ACYPI073473-PA	7.99e-10	59.3	2EA4H@1|root,2SZ18@2759|Eukaryota,38VIS@33154|Opisthokonta,3C5X1@33208|Metazoa,3DR66@33213|Bilateria,428IV@6656|Arthropoda,3SSBM@50557|Insecta	7029.ACYPI073473-PA|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156624_1	1131812.JQMS01000001_gene279	1.76e-11	70.5	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1HWKX@117743|Flavobacteriia,2P0A1@237|Flavobacterium	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
k59_27889_1	945713.IALB_0301	3.36e-127	374.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_127686_1	43151.ADAC006732-PA	5.18e-07	57.0	KOG0319@1|root,KOG0319@2759|Eukaryota,38BUJ@33154|Opisthokonta,3B9H7@33208|Metazoa,3CT9V@33213|Bilateria,41WW5@6656|Arthropoda,3SGNN@50557|Insecta,4508H@7147|Diptera,45E0I@7148|Nematocera	33208|Metazoa	A	Utp13 specific WD40 associated domain	TBL3	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0030515,GO:0030684,GO:0030686,GO:0031974,GO:0031981,GO:0032040,GO:0032991,GO:0034388,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904	-	ko:K14555	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Utp13,WD40
k59_109919_2	316274.Haur_1687	6.57e-94	283.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi,376EH@32061|Chloroflexia	32061|Chloroflexia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_10074_1	1249627.D779_1354	5.04e-57	195.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_168975_1	1047013.AQSP01000140_gene2447	1.97e-103	311.0	COG3328@1|root,COG3328@2|Bacteria,2NQXQ@2323|unclassified Bacteria	2|Bacteria	L	COGs COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_74682_1	313606.M23134_04015	6.35e-52	190.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_57647_2	4577.GRMZM2G116142_P01	1.9e-06	53.1	28HC0@1|root,2QPQD@2759|Eukaryota,37QN4@33090|Viridiplantae,3GHPB@35493|Streptophyta,3M3XC@4447|Liliopsida,3IB7W@38820|Poales	35493|Streptophyta	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_110418_1	1499967.BAYZ01000119_gene3216	5.49e-82	276.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
k59_133916_1	671143.DAMO_0272	7.39e-20	94.0	COG0859@1|root,COG3307@1|root,COG0859@2|Bacteria,COG3307@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	rfaQ	-	-	ko:K02841,ko:K02843,ko:K02847,ko:K02849,ko:K21003	ko00540,ko01100,ko02025,map00540,map01100,map02025	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	9.B.67.4,9.B.67.5	GT9	-	Glyco_transf_25,Glyco_transf_9,Wzy_C
k59_81170_2	388467.A19Y_1366	5.65e-42	141.0	COG2402@1|root,COG2402@2|Bacteria,1G79E@1117|Cyanobacteria,1HBMU@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_99227_1	338963.Pcar_0570	1.17e-34	129.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43UHV@69541|Desulfuromonadales	28221|Deltaproteobacteria	JKL	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_120929_2	43759.JNWK01000035_gene3291	4.78e-17	76.6	COG1670@1|root,COG1670@2|Bacteria,2IS7Y@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_38807_1	1121481.AUAS01000003_gene3880	6.5e-18	89.0	COG0438@1|root,COG0438@2|Bacteria,4NGU7@976|Bacteroidetes,47NJ9@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_109121_2	1379698.RBG1_1C00001G1112	6.18e-21	86.7	COG1551@1|root,COG1551@2|Bacteria,2NQ31@2323|unclassified Bacteria	2|Bacteria	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563,ko:K13626	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko02035,ko03019	-	-	-	CsrA
k59_109121_3	1163408.UU9_02244	2.47e-06	52.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1X404@135614|Xanthomonadales	135614|Xanthomonadales	N	Belongs to the bacterial flagellin family	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_185165_1	3880.AES58603	1.95e-129	397.0	COG1007@1|root,KOG4668@2759|Eukaryota,37KKM@33090|Viridiplantae,3GCSG@35493|Streptophyta,4JT2P@91835|fabids	35493|Streptophyta	C	Proton-conducting membrane transporter	nad2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_68154_1	7955.ENSDARP00000110408	1.58e-35	150.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,48B0V@7711|Chordata,499U9@7742|Vertebrata,4A6MN@7898|Actinopterygii	33208|Metazoa	L	K02A2.6-like	GIN1	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k59_27163_1	400682.PAC_15725343	9.02e-49	184.0	2D43P@1|root,2STRT@2759|Eukaryota,3AAAX@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_62289_1	1122222.AXWR01000016_gene2531	4.76e-54	192.0	COG3794@1|root,COG3794@2|Bacteria,1WM8A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
k59_114671_2	880073.Calab_0923	1.01e-09	61.2	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
k59_3817_1	72658.Bostr.14216s0004.1.p	5.72e-57	177.0	KOG4669@1|root,KOG4669@2759|Eukaryota,37WZU@33090|Viridiplantae,3GKXW@35493|Streptophyta	35493|Streptophyta	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K03882	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q2
k59_3817_2	4572.TRIUR3_19960-P1	2.31e-06	54.3	COG0197@1|root,COG2801@1|root,KOG0017@2759|Eukaryota,KOG3422@2759|Eukaryota,38965@33090|Viridiplantae,3GY34@35493|Streptophyta,3MB2Z@4447|Liliopsida,3IUMP@38820|Poales	35493|Streptophyta	J	Ribosomal protein L16p/L10e	-	-	-	ko:K02878,ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16,Ribosomal_S3_C
k59_121314_1	652103.Rpdx1_3876	7.68e-05	48.5	COG2199@1|root,COG2703@1|root,COG2703@2|Bacteria,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,2TU9T@28211|Alphaproteobacteria,3JRRT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K07216,ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_121314_2	1082931.KKY_2130	6.92e-09	59.3	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,2U4N2@28211|Alphaproteobacteria,3N7NT@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	EG	EamA-like transporter family	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_39183_1	1121405.dsmv_3289	1.34e-39	148.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_62302_1	626418.bglu_2g05140	4.59e-11	66.6	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2VZH0@28216|Betaproteobacteria,1K0ZC@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
k59_27469_1	754477.Q7C_782	7.87e-34	132.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,45ZN0@72273|Thiotrichales	72273|Thiotrichales	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_132897_1	880073.Calab_0674	3.07e-56	198.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
k59_114681_1	224325.AF_1141	7.41e-63	207.0	COG1960@1|root,arCOG01707@2157|Archaea,2XT5S@28890|Euryarchaeota,245Z3@183980|Archaeoglobi	183980|Archaeoglobi	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_156176_1	27923.ML011739a-PA	1.04e-09	65.1	2CN0N@1|root,2QT5H@2759|Eukaryota,38HD6@33154|Opisthokonta,3BBJ8@33208|Metazoa	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2,Endonuclease_7
k59_15801_2	102107.XP_008223735.1	0.0	1115.0	COG1007@1|root,KOG4668@2759|Eukaryota,37P90@33090|Viridiplantae,3GBJ3@35493|Streptophyta,4JRH7@91835|fabids	35493|Streptophyta	C	A subunit of NADH dehydrogenase	ndhF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_173778_1	6087.XP_004212483.1	2.04e-182	550.0	2CNBH@1|root,2QV0C@2759|Eukaryota,39RJ7@33154|Opisthokonta,3BH5Z@33208|Metazoa	33208|Metazoa	S	Zinc finger MYM-type protein 1-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_9620_2	517418.Ctha_1563	8.42e-35	132.0	COG1003@1|root,COG1003@2|Bacteria,1FDEN@1090|Chlorobi	1090|Chlorobi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_50330_2	1117314.PCIT_12829	9.58e-37	139.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	infB	-	-	ko:K02519,ko:K03832	-	-	-	-	ko00000,ko02000,ko03012,ko03029	2.C.1.1	-	-	CarbopepD_reg_2,Gram_pos_anchor,HtaA,TonB_C,YSIRK_signal,YXWGXW
k59_50333_1	1379698.RBG1_1C00001G1858	3.97e-07	57.8	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
k59_50333_2	880073.Calab_2502	3.66e-35	137.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
k59_85917_1	439235.Dalk_2243	2.73e-130	393.0	COG1055@1|root,COG1055@2|Bacteria,1QUC0@1224|Proteobacteria,43BR6@68525|delta/epsilon subdivisions,2WJVM@28221|Deltaproteobacteria,2MIF3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM sodium sulfate symporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp
k59_173787_1	880073.Calab_3318	1.1e-25	110.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_180249_2	1379698.RBG1_1C00001G0202	3.4e-39	138.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_85923_1	1185766.DL1_01875	0.000191	46.6	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2XMGS@285107|Thioclava	28211|Alphaproteobacteria	KT	diguanylate cyclase	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_138845_1	1232437.KL662077_gene1941	2.17e-122	364.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43BQX@68525|delta/epsilon subdivisions,2X71W@28221|Deltaproteobacteria,2MIFV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_180256_1	1125863.JAFN01000001_gene71	2.46e-77	261.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k59_85926_1	644282.Deba_2109	2.49e-39	152.0	COG4775@1|root,COG5616@1|root,COG4775@2|Bacteria,COG5616@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_144858_1	316067.Geob_0469	1.45e-99	301.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_168552_2	886379.AEWI01000030_gene306	7.37e-94	290.0	COG0212@1|root,COG0388@1|root,COG0212@2|Bacteria,COG0388@2|Bacteria,4NQRG@976|Bacteroidetes,2FQQB@200643|Bacteroidia,3XJW7@558415|Marinilabiliaceae	976|Bacteroidetes	H	5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_33180_1	1132442.KB889752_gene3426	2.66e-49	170.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,1ZBJU@1386|Bacillus	91061|Bacilli	E	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity	mcsB	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
k59_144868_1	7070.TC004268-PA	4.68e-26	110.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,41WI3@6656|Arthropoda,3SIRK@50557|Insecta	33208|Metazoa	O	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Baculo_F,RVT_1,rve,zf-H2C2
k59_185622_1	999550.KI421507_gene2650	6.94e-16	86.3	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR1S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
k59_21013_1	1187851.A33M_1701	5.07e-36	146.0	COG1345@1|root,COG1511@1|root,COG1345@2|Bacteria,COG1511@2|Bacteria,1QW8I@1224|Proteobacteria,2TU4X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	TMP_2
k59_21013_5	311402.Avi_6190	1.13e-19	87.0	2E1AD@1|root,32WQE@2|Bacteria,1N38M@1224|Proteobacteria,2UDR6@28211|Alphaproteobacteria,4BG8C@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacteriophage HK97-gp10, putative tail-component	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
k59_21013_8	1123242.JH636434_gene5645	1.44e-09	63.5	2CK39@1|root,32SBG@2|Bacteria,2J1K8@203682|Planctomycetes	203682|Planctomycetes	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
k59_21013_9	765698.Mesci_6262	1.13e-55	186.0	COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,43JIY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_138872_2	871968.DESME_14470	0.0008	42.7	COG5017@1|root,COG5017@2|Bacteria,1V2RT@1239|Firmicutes,24NVB@186801|Clostridia	186801|Clostridia	M	D-glucuronyl C5-epimerase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	C5-epim_C
k59_185629_1	997352.HMPREF9419_1377	4.63e-53	185.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,2FNRE@200643|Bacteroidia	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	lktB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_121361_1	1000565.METUNv1_00538	1.72e-06	55.1	COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2VN8K@28216|Betaproteobacteria,2KXMM@206389|Rhodocyclales	206389|Rhodocyclales	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
k59_91721_1	1121943.KB899997_gene1767	1.39e-10	60.8	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,1XJGW@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_91721_2	1121878.AUGL01000002_gene2422	1.93e-33	120.0	COG3324@1|root,COG3324@2|Bacteria,1N9ZV@1224|Proteobacteria,1SEWQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
k59_56835_1	1158762.KB898045_gene454	2.87e-29	106.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,1SDQ0@1236|Gammaproteobacteria,1WZ3Y@135613|Chromatiales	135613|Chromatiales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k59_56835_2	1304275.C41B8_09221	3.14e-49	157.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S99Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Addiction module toxin, Txe YoeB	yoeB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006379,GO:0006401,GO:0006402,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016458,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017148,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0042710,GO:0043021,GO:0043024,GO:0043170,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044764,GO:0044877,GO:0045947,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0098795,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:2000112,GO:2000113	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k59_114732_1	330214.NIDE4314	1.36e-15	77.8	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114732_2	1379698.RBG1_1C00001G1249	3.52e-45	155.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_91733_1	459495.SPLC1_S080700	7.1e-17	84.3	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_132961_1	32051.SynWH7803_1358	7.68e-07	51.2	COG1853@1|root,COG1853@2|Bacteria,1G2RV@1117|Cyanobacteria,1GYSV@1129|Synechococcus	1117|Cyanobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_93367_1	1469607.KK073768_gene3163	4.28e-30	115.0	COG4804@1|root,COG4804@2|Bacteria,1G1QU@1117|Cyanobacteria,1HM6D@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
k59_93367_2	1392486.JIAF01000004_gene1606	1.74e-21	92.8	COG4804@1|root,COG4804@2|Bacteria,4NE0Q@976|Bacteroidetes,2FM2V@200643|Bacteroidia	976|Bacteroidetes	S	cog cog4804	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
k59_170043_1	7668.SPU_009264-tr	1.2e-109	357.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,RVT_1
k59_128964_1	261292.Nit79A3_3318	9.42e-19	90.9	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VMY9@28216|Betaproteobacteria,371V4@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Insecticidal toxin complex protein TcaC	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
k59_122919_1	880073.Calab_1323	1.16e-31	123.0	COG0330@1|root,COG0330@2|Bacteria,2NP2X@2323|unclassified Bacteria	2|Bacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_70235_1	880072.Desac_1320	2e-38	136.0	COG0517@1|root,COG0517@2|Bacteria,1NKW9@1224|Proteobacteria,42XMW@68525|delta/epsilon subdivisions,2WT24@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_17598_1	314230.DSM3645_28962	2.32e-07	60.5	COG0591@1|root,COG0591@2|Bacteria,2J22E@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_58341_1	10224.XP_002739487.1	1.32e-34	143.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3BPSU@33208|Metazoa,3E41R@33213|Bilateria	33208|Metazoa	IQ	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_170049_1	1379698.RBG1_1C00001G0987	8.23e-115	347.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_70242_1	1385511.N783_02190	1.58e-53	173.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4HHA1@91061|Bacilli,2YABR@289201|Pontibacillus	91061|Bacilli	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_175348_1	126957.SMAR011345-PA	1.08e-30	124.0	2D8P2@1|root,2TAZI@2759|Eukaryota,39620@33154|Opisthokonta,3CMWM@33208|Metazoa,3DJYK@33213|Bilateria,423KU@6656|Arthropoda	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175360_2	1120966.AUBU01000014_gene652	2.13e-11	63.9	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,47QW9@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_175360_3	500635.MITSMUL_03268	8.95e-26	102.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4H3YJ@909932|Negativicutes	909932|Negativicutes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_81931_1	252305.OB2597_16030	0.000118	51.6	COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1QW4H@1224|Proteobacteria	1224|Proteobacteria	M	Rhs Family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Big_3_2,Big_3_5,DUF4082,DUF4347,He_PIG
k59_40634_1	56780.SYN_00535	2.93e-72	223.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2MS0Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_40634_2	56780.SYN_03783	4.03e-12	62.0	2FA5F@1|root,33ZQN@2|Bacteria,1NXGX@1224|Proteobacteria,430AQ@68525|delta/epsilon subdivisions,2WW50@28221|Deltaproteobacteria,2MS2H@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_181796_1	401526.TcarDRAFT_0275	8.14e-26	111.0	COG2199@1|root,COG3706@2|Bacteria,1V469@1239|Firmicutes,4H4YE@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,PAS_9
k59_157679_1	7955.ENSDARP00000110408	1.45e-27	117.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,48B0V@7711|Chordata,499U9@7742|Vertebrata,4A6MN@7898|Actinopterygii	33208|Metazoa	L	K02A2.6-like	GIN1	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k59_81944_1	3649.evm.model.supercontig_0.66	2.21e-06	46.2	2CYIR@1|root,2S4NT@2759|Eukaryota,37W8S@33090|Viridiplantae,3GKMR@35493|Streptophyta,3I1J5@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11230_2	526222.Desal_2316	1.14e-62	205.0	COG0515@1|root,COG0515@2|Bacteria,1MVPF@1224|Proteobacteria,42PCV@68525|delta/epsilon subdivisions,2WJHA@28221|Deltaproteobacteria,2M8MX@213115|Desulfovibrionales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_157682_1	56780.SYN_00606	3.01e-149	435.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_46421_1	1191523.MROS_0516	1.11e-16	87.0	COG0265@1|root,COG3209@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,DUF1565,PDZ_2,Trypsin_2
k59_187326_1	118005.AWNK01000009_gene222	1.44e-05	54.3	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
k59_164327_1	6669.EFX64418	2e-09	63.9	2CZKJ@1|root,2SATZ@2759|Eukaryota	2759|Eukaryota	S	RNase H	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H
k59_152462_1	574087.Acear_1434	4.46e-26	114.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WAHY@53433|Halanaerobiales	186801|Clostridia	T	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_22665_2	565655.ECBG_03140	3.46e-13	69.7	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,4AZX7@81852|Enterococcaceae	91061|Bacilli	E	Oligopeptidase F	pepF2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_29086_2	1550091.JROE01000001_gene4121	1.18e-20	87.4	2ETMH@1|root,33M58@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_116281_2	1280390.CBQR020000144_gene3599	4.81e-14	75.9	COG1309@1|root,COG1309@2|Bacteria,1V9XJ@1239|Firmicutes	1239|Firmicutes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
k59_46450_1	1120998.AUFC01000003_gene1534	5.47e-10	65.1	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,3WD7E@538999|Clostridiales incertae sedis	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_122954_1	44251.PDUR_02625	5.91e-06	45.8	COG0599@1|root,COG0599@2|Bacteria,1VWSB@1239|Firmicutes,4HJ1V@91061|Bacilli,276HN@186822|Paenibacillaceae	91061|Bacilli	S	Carboxymuconolactone decarboxylase family	yphJ	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
k59_122954_2	338969.Rfer_2440	4.41e-24	97.4	COG0702@1|root,COG0702@2|Bacteria,1MVBE@1224|Proteobacteria,2VQZH@28216|Betaproteobacteria,4AEN3@80864|Comamonadaceae	28216|Betaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
k59_134589_2	1121378.KB899739_gene3789	1.18e-09	65.9	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_181831_1	880073.Calab_0513	4.49e-31	124.0	2C3GN@1|root,31EWU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175410_1	7029.ACYPI20122-PA	0.000162	43.9	29K2B@1|root,2RTB8@2759|Eukaryota,3ATQK@33154|Opisthokonta,3C4XH@33208|Metazoa,3DJZB@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
k59_40677_1	1379698.RBG1_1C00001G1076	6.24e-81	266.0	COG3696@1|root,COG3696@2|Bacteria,2NP07@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_104886_1	479433.Caci_6865	1.53e-52	187.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	CBM_20,CBM_6,DUF5110,Glyco_hydro_31
k59_111134_1	7029.ACYPI21914-PA	3.45e-59	209.0	2EM9Q@1|root,2SQZT@2759|Eukaryota,3APBT@33154|Opisthokonta,3C1E7@33208|Metazoa,3DHIP@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371
k59_170127_2	1166018.FAES_1629	1.4e-28	114.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
k59_157715_1	288000.BBta_6814	2.1e-154	492.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,3JQV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_75843_1	1382306.JNIM01000001_gene787	2.73e-67	214.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
k59_75846_1	485913.Krac_2407	1.16e-30	120.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_N
k59_134620_1	1397528.Q671_08895	9.59e-41	145.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,1RNRG@1236|Gammaproteobacteria,1XQYS@135619|Oceanospirillales	135619|Oceanospirillales	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_70310_1	1254432.SCE1572_02785	1.15e-131	405.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,42QDJ@68525|delta/epsilon subdivisions,2WIJ9@28221|Deltaproteobacteria,2Z2XS@29|Myxococcales	28221|Deltaproteobacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
k59_81994_2	6500.XP_005109035.1	9.69e-166	490.0	28PUT@1|root,2QWHD@2759|Eukaryota,38EA4@33154|Opisthokonta,3BMU4@33208|Metazoa,3CZSB@33213|Bilateria	33208|Metazoa	S	Transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7,Tnp_zf-ribbon_2
k59_93456_2	338966.Ppro_1442	3.14e-11	64.7	COG0778@1|root,COG0778@2|Bacteria,1RA6E@1224|Proteobacteria,42XB2@68525|delta/epsilon subdivisions,2WT59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_187408_1	7897.ENSLACP00000005054	7.47e-172	516.0	28HC0@1|root,2QPQD@2759|Eukaryota,392P6@33154|Opisthokonta,3BH6I@33208|Metazoa,3D0QV@33213|Bilateria,48CBX@7711|Chordata	33208|Metazoa	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_76323_1	406817.XNC1_4455	2.86e-88	260.0	COG3293@1|root,COG3293@2|Bacteria,1RBFK@1224|Proteobacteria,1S22S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Pfam Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k59_36663_1	118168.MC7420_6652	1.04e-40	154.0	COG2885@1|root,COG2885@2|Bacteria,1G1ET@1117|Cyanobacteria,1H9C7@1150|Oscillatoriales	1117|Cyanobacteria	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009522,GO:0009579,GO:0016020,GO:0030075,GO:0030094,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02689	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k59_112721_1	8479.XP_008168787.1	2.51e-60	201.0	2CMVD@1|root,2QS6T@2759|Eukaryota,38ITZ@33154|Opisthokonta,3BGFP@33208|Metazoa,3D162@33213|Bilateria,482X8@7711|Chordata,493ZA@7742|Vertebrata,4CHPK@8459|Testudines	33208|Metazoa	S	Domain of unknown function (DUF4371)	GTF2IRD2	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0007275,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0014733,GO:0014883,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043502,GO:0044057,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0048583,GO:0048856,GO:0050789,GO:0050794,GO:0051171,GO:0051239,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0090257,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,GTF2I
k59_48190_1	1379698.RBG1_1C00001G1218	8.36e-40	152.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
k59_71632_1	1379698.RBG1_1C00001G1787	1.78e-51	186.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
k59_106875_1	439235.Dalk_1272	4.33e-14	71.6	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MHKE@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_95274_1	1121382.JQKG01000013_gene499	4.4e-55	181.0	COG0667@1|root,COG0667@2|Bacteria,1WJ87@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_95274_2	1192034.CAP_4236	3.05e-07	52.8	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159906_1	483219.LILAB_26730	7.31e-59	199.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,2YU0X@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_136363_1	1499967.BAYZ01000028_gene1333	1.99e-61	205.0	COG3829@1|root,COG3829@2|Bacteria,2NQNU@2323|unclassified Bacteria	2|Bacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_71634_1	1536773.R70331_04335	9.04e-05	53.5	COG2304@1|root,COG2304@2|Bacteria,1V01Q@1239|Firmicutes,4HE4F@91061|Bacilli,26TQZ@186822|Paenibacillaceae	91061|Bacilli	S	Von Willebrand factor	vWFA2	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_148036_1	1121430.JMLG01000006_gene1765	6.54e-57	184.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,261GH@186807|Peptococcaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
k59_148036_2	945713.IALB_2192	1.63e-08	55.1	COG0540@1|root,COG0540@2|Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
k59_106885_2	1379698.RBG1_1C00001G0447	8.12e-38	134.0	COG3880@1|root,COG3880@2|Bacteria,2NRIE@2323|unclassified Bacteria	2|Bacteria	S	UvrB/uvrC motif	CP_0046	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	GSu_C4xC__C2xCH,UVR
k59_7222_1	1227352.C173_15359	1.04e-13	68.2	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_7222_2	545243.BAEV01000030_gene445	3.2e-05	47.4	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,36DQW@31979|Clostridiaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_112736_1	880073.Calab_2742	4.43e-32	128.0	COG0383@1|root,COG0383@2|Bacteria,2NNPD@2323|unclassified Bacteria	2|Bacteria	G	Glycoside hydrolase family 38 central region	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
k59_112737_1	411467.BACCAP_00058	1.04e-05	48.1	COG1132@1|root,COG1132@2|Bacteria,1UHQP@1239|Firmicutes,25E4H@186801|Clostridia,2686U@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter transmembrane region	cydC	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_83467_2	861299.J421_2400	2.51e-31	123.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_7241_1	34740.HMEL002884-PA	6.4e-61	219.0	KOG1075@1|root,KOG4338@1|root,KOG1075@2759|Eukaryota,KOG4338@2759|Eukaryota,38D8A@33154|Opisthokonta,3BCAR@33208|Metazoa,3CYWB@33213|Bilateria,41XU6@6656|Arthropoda,3SJX5@50557|Insecta,442MC@7088|Lepidoptera	33208|Metazoa	I	von Willebrand factor (vWF) type D domain	-	GO:0003674,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015850,GO:0015918,GO:0016020,GO:0032368,GO:0032370,GO:0032879,GO:0033036,GO:0034196,GO:0044421,GO:0044464,GO:0045178,GO:0048518,GO:0050789,GO:0051049,GO:0051050,GO:0051179,GO:0051234,GO:0065007,GO:0070325,GO:0071702,GO:0071944,GO:1905952,GO:1905954	-	-	-	-	-	-	-	-	-	-	C8,DUF1081,DUF1943,VWD,Vitellogenin_N
k59_142086_1	7668.SPU_016473-tr	2.61e-18	84.0	28MXD@1|root,2QUFX@2759|Eukaryota,38TCJ@33154|Opisthokonta,3BIIF@33208|Metazoa,3D2PH@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142086_2	7739.XP_002606696.1	1.32e-73	257.0	2D18H@1|root,2SH4Q@2759|Eukaryota,3AJ24@33154|Opisthokonta,3BYE1@33208|Metazoa,3DD8X@33213|Bilateria,48R8R@7711|Chordata	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60006_1	85681.XP_006440907.1	8.64e-39	152.0	28PQ2@1|root,2QWCA@2759|Eukaryota,37NA7@33090|Viridiplantae,3GAAP@35493|Streptophyta	35493|Streptophyta	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_60006_2	3750.XP_008386065.1	8.9e-28	124.0	COG2801@1|root,KOG0017@2759|Eukaryota,37R0H@33090|Viridiplantae	33090|Viridiplantae	L	Zinc finger MYM-type protein 1-like	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124687_1	903818.KI912268_gene1030	8.27e-25	109.0	COG0643@1|root,COG0643@2|Bacteria,3Y40G@57723|Acidobacteria	57723|Acidobacteria	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_24917_1	880073.Calab_0626	1.83e-72	229.0	COG1250@1|root,COG1250@2|Bacteria,2NQAW@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd2	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_159946_1	7029.ACYPI38704-PA	2e-20	98.6	28PAK@1|root,2QVXX@2759|Eukaryota,39Z25@33154|Opisthokonta,3BNRK@33208|Metazoa	33208|Metazoa	S	nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,MULE,SWIM
k59_42504_1	880073.Calab_3099	4.75e-106	325.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_48234_1	1278073.MYSTI_03474	3.27e-15	81.6	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1MVIW@1224|Proteobacteria,43C2N@68525|delta/epsilon subdivisions,2X7D8@28221|Deltaproteobacteria,2YVWI@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_8
k59_60015_1	7897.ENSLACP00000012647	7.42e-09	62.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3E42K@33213|Bilateria,48QQV@7711|Chordata,49MAI@7742|Vertebrata	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_159954_1	1333856.L686_11030	2.06e-37	139.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RYNH@1236|Gammaproteobacteria,1Z0Q9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_106934_1	1121479.AUBS01000003_gene4152	9.8e-12	67.4	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2TV8R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	phosphatidylethanolamine N-methyltransferase	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_18738_1	326424.FRAAL2344	5.56e-42	156.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4ES90@85013|Frankiales	201174|Actinobacteria	I	Carbamoyl-phosphate synthase L chain	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_18738_2	1121935.AQXX01000122_gene5656	2.37e-06	48.9	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1XHW2@135619|Oceanospirillales	135619|Oceanospirillales	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_118905_1	518766.Rmar_0586	9.37e-60	196.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,1FIUJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_153886_1	1041147.AUFB01000050_gene4052	2.17e-25	107.0	COG3385@1|root,COG3385@2|Bacteria,1PHKQ@1224|Proteobacteria,2VGVZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_89318_1	706587.Desti_4208	8.06e-34	133.0	COG3852@1|root,COG5000@1|root,COG3852@2|Bacteria,COG5000@2|Bacteria,1R1JU@1224|Proteobacteria,43DA4@68525|delta/epsilon subdivisions,2X8GR@28221|Deltaproteobacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	regM	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_83515_2	1246626.BleG1_3837	2.32e-17	79.3	2AQ3S@1|root,31F91@2|Bacteria,1U9YV@1239|Firmicutes,4IK6S@91061|Bacilli,1ZGG3@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_153888_1	13735.ENSPSIP00000000456	3.51e-22	97.4	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,48B0V@7711|Chordata,499U9@7742|Vertebrata,4CK8P@8459|Testudines	33208|Metazoa	L	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k59_60039_1	706587.Desti_0283	8.78e-32	116.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_60039_2	1408428.JNJP01000001_gene3251	5.84e-35	135.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_54229_1	998674.ATTE01000001_gene748	9.5e-24	108.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,462HB@72273|Thiotrichales	72273|Thiotrichales	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_13140_1	7668.SPU_000714-tr	5.9e-103	337.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_154585_1	323848.Nmul_A1531	6.68e-06	50.4	COG1396@1|root,COG1396@2|Bacteria,1NK58@1224|Proteobacteria,2W57Q@28216|Betaproteobacteria,373EU@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_63406_1	244447.XP_008333619.1	8.56e-114	371.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3B9WN@33208|Metazoa,3D1S8@33213|Bilateria,48C1W@7711|Chordata,49N8J@7742|Vertebrata,4A94B@7898|Actinopterygii	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_174899_1	459349.CLOAM1866	3.14e-05	52.4	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_10807_1	696747.NIES39_L05690	2.75e-05	47.4	COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_10807_2	96561.Dole_1931	5.93e-27	110.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2MI1J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
k59_57846_1	941449.dsx2_0270	4.95e-14	73.9	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,2M843@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Cation transporter	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_57846_2	1211035.CD30_02545	3.29e-07	52.4	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,3IW91@400634|Lysinibacillus	91061|Bacilli	P	Potassium transporter Trk	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_63418_1	431943.CKL_3571	1.11e-54	193.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_17055_1	1121935.AQXX01000142_gene2305	1.84e-52	184.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XH7K@135619|Oceanospirillales	135619|Oceanospirillales	C	NADH-quinone oxidoreductase subunit F	-	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
k59_151839_1	1125863.JAFN01000001_gene556	2.93e-18	87.4	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k59_57857_1	633147.Olsu_1000	1.85e-28	115.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CUJN@84998|Coriobacteriia	84998|Coriobacteriia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
k59_63426_1	257363.RT0546	5.92e-06	55.1	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,47GDR@766|Rickettsiales	766|Rickettsiales	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
k59_34165_1	1120973.AQXL01000129_gene2404	2.99e-69	231.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,2788R@186823|Alicyclobacillaceae	91061|Bacilli	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_17060_1	1205680.CAKO01000027_gene4699	6.66e-08	62.8	COG3210@1|root,COG4625@1|root,COG4934@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4934@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Big_3_2,CAP,Calx-beta,DUF11,DUF4347,Exo_endo_phos,He_PIG,fn3
k59_75380_1	1379698.RBG1_1C00001G0521	7.12e-134	391.0	COG1071@1|root,COG1071@2|Bacteria,2NPBB@2323|unclassified Bacteria	2|Bacteria	C	Dehydrogenase E1 component	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_57863_1	1379698.RBG1_1C00001G1765	2.13e-75	236.0	COG0438@1|root,COG0438@2|Bacteria,2NNTN@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_122490_1	1379698.RBG1_1C00001G0595	6.43e-31	121.0	COG1874@1|root,COG1874@2|Bacteria,2NRR5@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_35,Glyco_hydro_42,Glyco_hydro_42M,Sulfotransfer_2
k59_122490_2	880073.Calab_0648	2.54e-15	76.3	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
k59_115805_1	1121472.AQWN01000009_gene433	6.74e-20	90.1	COG1413@1|root,COG1413@2|Bacteria,1VFIG@1239|Firmicutes,24STM@186801|Clostridia	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_EZ
k59_57875_1	880073.Calab_0988	8.73e-54	188.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2NPAA@2323|unclassified Bacteria	2|Bacteria	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
k59_34194_1	1132442.KB889752_gene2198	6.72e-74	232.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_169696_1	7668.SPU_007351-tr	4.05e-20	92.8	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_81407_1	926561.KB900619_gene2505	1.4e-08	61.6	COG4796@1|root,COG4796@2|Bacteria,1UK31@1239|Firmicutes,24Z85@186801|Clostridia,3WBE3@53433|Halanaerobiales	186801|Clostridia	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
k59_146030_1	1454004.AW11_02264	2.61e-104	317.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,2W02U@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_51152_1	1317122.ATO12_02650	1.43e-42	156.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2YIJU@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_87227_2	880073.Calab_2124	6.75e-54	182.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484	-	ko:K02358,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_22191_1	525903.Taci_1363	7.53e-27	105.0	COG1418@1|root,COG1418@2|Bacteria,3TAN7@508458|Synergistetes	508458|Synergistetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_22191_2	1961.JOAK01000016_gene5336	1.07e-10	65.5	COG2274@1|root,COG2274@2|Bacteria,2GMR3@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_92924_1	31234.CRE23042	6.09e-32	124.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_122503_1	690850.Desaf_2573	4.67e-82	257.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,42Q8I@68525|delta/epsilon subdivisions,2X5IX@28221|Deltaproteobacteria,2MA7R@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_63475_1	1415778.JQMM01000001_gene875	2.4e-32	132.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1J56C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_128483_1	338966.Ppro_1321	5.2e-73	231.0	COG3267@1|root,COG3267@2|Bacteria,1Q4DA@1224|Proteobacteria,42YYB@68525|delta/epsilon subdivisions,2WU9J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_17105_1	1255043.TVNIR_3280	2.19e-139	413.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,1RYKV@1236|Gammaproteobacteria,1X06D@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_63477_1	452637.Oter_3717	6.32e-35	136.0	COG1554@1|root,COG1554@2|Bacteria,46U1D@74201|Verrucomicrobia	74201|Verrucomicrobia	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_87240_1	382464.ABSI01000010_gene3476	1.91e-33	130.0	COG0407@1|root,COG5012@1|root,COG0407@2|Bacteria,COG5012@2|Bacteria,46V92@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_87240_2	1191523.MROS_2096	1.28e-14	76.6	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
k59_146051_1	10224.XP_006814613.1	2.05e-31	121.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39MPK@33154|Opisthokonta,3CP9W@33208|Metazoa,3E5EG@33213|Bilateria	33208|Metazoa	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Exo_endo_phos_2
k59_139874_1	3659.XP_004162279.1	2.22e-82	246.0	COG1005@1|root,KOG4770@2759|Eukaryota,37V23@33090|Viridiplantae,3GIN5@35493|Streptophyta	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)	nad1	GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114	1.6.5.3	ko:K03878	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_99408_1	1191523.MROS_2798	1.17e-125	391.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
k59_5061_1	226185.EF_2757	1.55e-18	86.7	COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,4AZJB@81852|Enterococcaceae	91061|Bacilli	S	Uncharacterised protein family (UPF0014)	ybbM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k59_5061_2	1245471.PCA10_40710	0.000503	43.9	COG4175@1|root,COG4176@1|root,COG4175@2|Bacteria,COG4176@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1YCT2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
k59_122557_1	1233950.IW22_22400	1.63e-36	142.0	COG0705@1|root,COG0705@2|Bacteria,4NP9G@976|Bacteroidetes,1I9DW@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k59_146071_1	1348114.OM33_19150	7.9e-18	89.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,2PZMF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_134100_1	3988.XP_002535312.1	0.0	992.0	COG0197@1|root,KOG3422@2759|Eukaryota,38965@33090|Viridiplantae,3GY34@35493|Streptophyta,4JV2J@91835|fabids	35493|Streptophyta	J	RIBOSOMAL protein	-	-	-	ko:K02878,ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16,Ribosomal_S3_C
k59_22232_1	448385.sce5204	9.58e-59	203.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
k59_22240_1	13735.ENSPSIP00000011102	5.61e-45	166.0	2CN11@1|root,2QT83@2759|Eukaryota,38D3X@33154|Opisthokonta,3BDRF@33208|Metazoa,3CX54@33213|Bilateria,482YQ@7711|Chordata,494V4@7742|Vertebrata	33208|Metazoa	S	DNA-binding transcription factor activity, RNA polymerase II-specific	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT
k59_75953_2	7425.NV26111-PA	3.03e-59	219.0	COG2801@1|root,KOG0017@2759|Eukaryota,39MQW@33154|Opisthokonta,3CPAY@33208|Metazoa,3E5FP@33213|Bilateria	33208|Metazoa	L	Transposase protein	-	-	-	-	-	-	-	-	-	-	-	-	THAP,Tnp_P_element
k59_46630_1	984262.SGRA_3671	5.1e-84	279.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_43591_1	1173024.KI912154_gene929	1.22e-22	101.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1JI2C@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k59_2592_1	1179773.BN6_03480	3.11e-06	48.1	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4E03K@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_14529_1	7668.SPU_010087-tr	4.51e-108	345.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_55531_2	1379698.RBG1_1C00001G0988	3.24e-28	120.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
k59_14535_1	13037.EHJ74163	8.56e-10	62.4	2F0VV@1|root,2T1Z5@2759|Eukaryota	13037.EHJ74163|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_32174_1	316274.Haur_4500	1.37e-26	115.0	COG3385@1|root,COG3385@2|Bacteria,2G7KG@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_143615_2	644282.Deba_0179	1.37e-39	141.0	COG0730@1|root,COG0730@2|Bacteria,1PYDH@1224|Proteobacteria,42P28@68525|delta/epsilon subdivisions,2WK6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_8619_2	7897.ENSLACP00000011019	3.41e-98	318.0	2CNDJ@1|root,2QVFB@2759|Eukaryota,39MN8@33154|Opisthokonta,3CP8H@33208|Metazoa,3E5D2@33213|Bilateria,48RT0@7711|Chordata,49N6G@7742|Vertebrata	33208|Metazoa	S	Transposase IS4	-	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0016604,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0070013	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k59_73077_1	76114.ebA145	3.22e-38	136.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2VR7A@28216|Betaproteobacteria,2KWHH@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
k59_137882_1	525263.HMPREF0298_0900	3.87e-16	79.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,22MWE@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,UPF0114
k59_49504_1	7029.ACYPI49381-PA	2.83e-54	209.0	COG0507@1|root,KOG1075@1|root,KOG0987@2759|Eukaryota,KOG1075@2759|Eukaryota,39MXV@33154|Opisthokonta,3CPH8@33208|Metazoa	2759|Eukaryota	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Helitron_like_N,PIF1
k59_126046_1	13037.EHJ67258	2.2e-37	150.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A4K9@33154|Opisthokonta,3BSC4@33208|Metazoa	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_102367_1	1453505.JASY01000007_gene1168	1.95e-47	172.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NTRC@237|Flavobacterium	976|Bacteroidetes	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
k59_61308_1	1203605.HMPREF1531_01642	2.05e-08	52.8	COG0102@1|root,COG0102@2|Bacteria	2|Bacteria	J	mRNA binding	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_61308_2	1229205.BUPH_03524	1.83e-32	118.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,1K751@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_126049_1	1173028.ANKO01000094_gene2601	1.19e-49	177.0	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1H7KQ@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_161571_1	269799.Gmet_2664	5.06e-22	99.8	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_172665_1	768710.DesyoDRAFT_0197	4.3e-69	222.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,260FF@186807|Peptococcaceae	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k59_131801_2	517417.Cpar_1990	1.57e-22	93.6	COG0816@1|root,COG0816@2|Bacteria,1FE4Q@1090|Chlorobi	1090|Chlorobi	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_172672_1	1340493.JNIF01000003_gene2186	5.72e-46	169.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
k59_67397_2	1218084.BBJK01000030_gene2842	1.54e-05	50.4	COG0451@1|root,COG0451@2|Bacteria,1MVPZ@1224|Proteobacteria,2VM2A@28216|Betaproteobacteria,1K0S3@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.135,1.1.1.281	ko:K15856,ko:K22252	ko00051,ko00520,map00051,map00520	-	R03396,R03397,R03398,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_38169_2	97138.C820_00191	5.18e-46	162.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,36ECF@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_2651_1	489825.LYNGBM3L_67160	1.49e-68	234.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase
k59_97072_1	1379698.RBG1_1C00001G1326	3.01e-188	530.0	COG2006@1|root,COG2006@2|Bacteria,2NPTK@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
k59_137914_1	690850.Desaf_3391	1.6e-26	106.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2MB8X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_155271_1	1193181.BN10_470025	7.72e-59	195.0	COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria,4FE3S@85021|Intrasporangiaceae	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
k59_131827_1	1173022.Cri9333_0577	6.39e-99	300.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_161595_1	7668.SPU_009591-tr	3.07e-05	52.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_120210_1	261292.Nit79A3_2501	1.8e-79	247.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHC7@28216|Betaproteobacteria,374M1@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_108407_1	1122915.AUGY01000081_gene3229	5.58e-35	130.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,26S4B@186822|Paenibacillaceae	91061|Bacilli	L	8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
k59_55605_1	272134.KB731325_gene566	3.86e-48	168.0	COG4467@1|root,COG4467@2|Bacteria	2|Bacteria	L	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_126095_1	1349785.BAUG01000027_gene1667	8.79e-07	54.3	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_84969_1	879212.DespoDRAFT_02827	3e-113	350.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,42X93@68525|delta/epsilon subdivisions,2WSXR@28221|Deltaproteobacteria,2MQ06@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_84969_2	882378.RBRH_00455	2.71e-72	229.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VP9S@28216|Betaproteobacteria,1K0PK@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_2683_1	933262.AXAM01000015_gene88	1.35e-20	92.8	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MISR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k59_84970_1	1173701.A0A066XIF8	1.37e-06	57.4	KOG1075@1|root,KOG1075@2759|Eukaryota,39XVS@33154|Opisthokonta,3P0R9@4751|Fungi,3QK2F@4890|Ascomycota,2182H@147550|Sordariomycetes,1F5A7@1028384|Glomerellales	4751|Fungi	S	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_55616_2	7668.SPU_004303-tr	2.04e-20	90.9	COG2801@1|root,KOG0017@2759|Eukaryota,39ZX7@33154|Opisthokonta,3BQ45@33208|Metazoa,3D40D@33213|Bilateria	33208|Metazoa	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Chromo,rve
k59_61339_1	7668.SPU_008007-tr	2.58e-47	175.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_143673_1	7029.ACYPI40907-PA	8.04e-42	152.0	2CXSV@1|root,2RZHU@2759|Eukaryota,3A25F@33154|Opisthokonta,3BP4P@33208|Metazoa,3E4H2@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_161612_1	3656.XP_008460615.1	9.72e-43	156.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta,4JM10@91835|fabids	35493|Streptophyta	H	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Chromo,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_126103_1	443144.GM21_0516	5.45e-57	200.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,43SAV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_14609_1	55952.BU52_02315	1.45e-16	84.3	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_49550_1	7425.NV25352-PA	7.96e-40	152.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria,421Y7@6656|Arthropoda,3SQJP@50557|Insecta,46MX8@7399|Hymenoptera	33208|Metazoa	S	Domain of unknown function (DUF4371)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_38888_1	1379698.RBG1_1C00001G0733	9.66e-55	199.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_168182_1	502025.Hoch_4573	3.46e-09	58.5	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
k59_9337_1	314282.PCNPT3_10365	1.15e-12	72.8	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,2QICU@267894|Psychromonadaceae	1236|Gammaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_27235_1	1089550.ATTH01000001_gene773	5.84e-44	163.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1FIX7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_179904_1	7668.SPU_022563-tr	6.03e-113	361.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39VXI@33154|Opisthokonta,3BY4F@33208|Metazoa,3DDBT@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_38640_1	264462.Bd3249	5.1e-32	126.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42MK8@68525|delta/epsilon subdivisions,2MUPR@213481|Bdellovibrionales,2WMI7@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_38640_2	1536773.R70331_03855	2.71e-11	66.6	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V8VV@1239|Firmicutes,4HVCT@91061|Bacilli,26VC5@186822|Paenibacillaceae	91061|Bacilli	T	cheY-homologous receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
k59_56098_1	56780.SYN_00568	3.61e-51	180.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_61816_1	401053.AciPR4_4057	5.1e-38	143.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_179622_1	7029.ACYPI006246-PA	2.45e-75	245.0	2DFMY@1|root,2S5SM@2759|Eukaryota,3A6U3@33154|Opisthokonta,3BSRM@33208|Metazoa,3E48V@33213|Bilateria,42AAE@6656|Arthropoda	33208|Metazoa	S	BED zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,zf-BED
k59_173273_3	264402.Cagra.21839s0002.1.p	2.88e-144	410.0	COG0755@1|root,2QTE6@2759|Eukaryota,37Q3M@33090|Viridiplantae,3GHFY@35493|Streptophyta	35493|Streptophyta	O	cytochrome c biosynthesis ccmC-like mitochondrial	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_3276_1	1121440.AUMA01000005_gene2728	1.04e-05	53.1	COG0500@1|root,COG2226@2|Bacteria,1RASQ@1224|Proteobacteria,42QTY@68525|delta/epsilon subdivisions,2WMN2@28221|Deltaproteobacteria,2MBR7@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_132397_1	1089550.ATTH01000001_gene1675	9.06e-45	163.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1FIT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_114240_1	69293.ENSGACP00000001805	1.03e-50	164.0	2CY47@1|root,2S1X0@2759|Eukaryota,3A4N9@33154|Opisthokonta,3BQU8@33208|Metazoa,3E42U@33213|Bilateria,48EW0@7711|Chordata,49C1M@7742|Vertebrata,4A7NR@7898|Actinopterygii	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61842_1	87626.PTD2_03861	1.98e-08	54.7	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria,2Q033@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ygfF	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_61842_2	323259.Mhun_3113	7.38e-57	191.0	arCOG09601@1|root,arCOG09601@2157|Archaea	2157|Archaea	S	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
k59_44136_1	756272.Plabr_0864	5.58e-35	134.0	COG1570@1|root,COG1570@2|Bacteria,2IXGG@203682|Planctomycetes	203682|Planctomycetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_61851_1	331678.Cphamn1_1692	2.21e-105	317.0	COG0668@1|root,COG0668@2|Bacteria,1FD89@1090|Chlorobi	1090|Chlorobi	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
k59_27024_2	1192034.CAP_7761	1.98e-33	120.0	COG3436@1|root,COG3436@2|Bacteria,1RHDW@1224|Proteobacteria,4360E@68525|delta/epsilon subdivisions,2X0HX@28221|Deltaproteobacteria,2Z0TS@29|Myxococcales	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_27024_3	159450.NH14_30640	6.67e-24	114.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,2WGG1@28216|Betaproteobacteria,1K2RM@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_162139_1	588726.J7R6R2	4.38e-33	129.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3NVKU@4751|Fungi,3QP1S@4890|Ascomycota,3RRCD@4891|Saccharomycetes,3RZKH@4893|Saccharomycetaceae	4751|Fungi	L	retrotransposon	-	GO:0003674,GO:0003824,GO:0003964,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006278,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	Peptidase_A2E,RVT_1,rve
k59_91191_1	281687.CJA15137	9.21e-21	98.6	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3DKJZ@33213|Bilateria,40GWW@6231|Nematoda,1KZYW@119089|Chromadorea,412EV@6236|Rhabditida	33208|Metazoa	K	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_79704_1	562970.Btus_1006	3.91e-91	280.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,279MM@186823|Alicyclobacillaceae	91061|Bacilli	E	Aminotransferase class-V	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_38692_1	1121930.AQXG01000017_gene3132	7.39e-61	194.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IY1V@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_38692_2	1499967.BAYZ01000022_gene253	6.51e-25	103.0	COG4591@1|root,COG4591@2|Bacteria,2NQAR@2323|unclassified Bacteria	2|Bacteria	M	MacB-like periplasmic core domain	VPA0559	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_9240_1	1379698.RBG1_1C00001G0264	1.77e-63	211.0	COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837,GO:2000112	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_79708_1	1116375.VEJY3_10155	1.28e-83	259.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1XVCY@135623|Vibrionales	135623|Vibrionales	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_9246_1	1123511.KB905872_gene1845	1.35e-63	207.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H53T@909932|Negativicutes	909932|Negativicutes	L	RNA-directed DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_179682_1	63737.Npun_R0801	1.62e-103	315.0	COG3385@1|root,COG3385@2|Bacteria,1GQDD@1117|Cyanobacteria	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68039_1	1379698.RBG1_1C00001G1319	1.69e-81	254.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_97723_1	7897.ENSLACP00000014528	2.21e-121	365.0	KOG1121@1|root,KOG1121@2759|Eukaryota,39WQ2@33154|Opisthokonta,3BJ35@33208|Metazoa,3CVNM@33213|Bilateria,48AHQ@7711|Chordata,49589@7742|Vertebrata	33208|Metazoa	L	protein dimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_hAT,zf-BED
k59_32662_2	1120941.AUBL01000016_gene2525	1.12e-24	94.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D6AF@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_79724_1	525897.Dbac_3407	1.3e-82	267.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_3310_1	1379698.RBG1_1C00001G1194	9.73e-21	104.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
k59_85484_1	909943.HIMB100_00008190	2.9e-64	211.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,4BP7R@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_85484_2	1382303.JPOM01000001_gene2102	1.03e-52	186.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2KFEV@204458|Caulobacterales	204458|Caulobacterales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_38717_1	1088721.NSU_1599	6.61e-11	68.2	COG4774@1|root,COG4774@2|Bacteria,1R5EH@1224|Proteobacteria,2UQHJ@28211|Alphaproteobacteria,2KDTT@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_79727_1	555079.Toce_2133	1.69e-208	606.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_49900_1	714943.Mucpa_6668	1.04e-31	117.0	COG1522@1|root,COG1522@2|Bacteria,4NMPD@976|Bacteroidetes,1ISU0@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_15259_1	502025.Hoch_5203	1.34e-44	165.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,433QQ@68525|delta/epsilon subdivisions,2WY7P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_44218_1	768670.Calni_1853	6.89e-90	290.0	COG4096@1|root,COG4096@2|Bacteria,2GGK0@200930|Deferribacteres	200930|Deferribacteres	L	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
k59_144260_1	941770.GL622178_gene5	1.66e-24	110.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae	91061|Bacilli	E	oligoendopeptidase F	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_185078_1	1209984.BN978_05071	6.29e-12	71.2	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,233WM@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_168012_1	400682.PAC_15700899	1.47e-64	223.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k59_109058_1	400682.PAC_15702057	1.03e-45	168.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,zf-RVT
k59_44231_1	6087.XP_002168266.2	2.43e-50	190.0	28M7P@1|root,2QTQS@2759|Eukaryota,39Z9X@33154|Opisthokonta,3BNGS@33208|Metazoa	33154|Opisthokonta	S	cellular response to interferon-beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120870_1	7425.NV25775-PA	1.11e-13	80.1	29SKP@1|root,2RXE4@2759|Eukaryota,3961W@33154|Opisthokonta,3CAFM@33208|Metazoa,3DRMN@33213|Bilateria,42BYC@6656|Arthropoda,3SQQ5@50557|Insecta,46M58@7399|Hymenoptera	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_20451_1	314278.NB231_00640	1.46e-29	118.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales	135613|Chromatiales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_15278_1	48698.ENSPFOP00000025644	7.76e-11	63.9	KOG1121@1|root,KOG1121@2759|Eukaryota,3A1BV@33154|Opisthokonta,3BQ1H@33208|Metazoa,3D9N1@33213|Bilateria,48GA6@7711|Chordata,49D8D@7742|Vertebrata,4A61R@7898|Actinopterygii	33208|Metazoa	L	BED zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_38750_1	1191523.MROS_2798	2.67e-158	478.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
k59_127414_1	522772.Dacet_2820	2.72e-118	365.0	COG4584@1|root,COG4584@2|Bacteria	2|Bacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_33302_1	1121405.dsmv_0198	6.1e-57	194.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2MHWP@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_173951_1	1122917.KB899680_gene416	1.15e-89	273.0	COG3509@1|root,COG3509@2|Bacteria,1UZE4@1239|Firmicutes,4I68A@91061|Bacilli,26RD5@186822|Paenibacillaceae	91061|Bacilli	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_121471_1	31234.CRE13126	1.94e-49	176.0	KOG4740@1|root,KOG4740@2759|Eukaryota,3A4S6@33154|Opisthokonta,3BUQE@33208|Metazoa,3E551@33213|Bilateria,40FH4@6231|Nematoda,1KYF2@119089|Chromadorea,414KC@6236|Rhabditida	33208|Metazoa	S	proton channel activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,PAX
k59_43168_2	234267.Acid_6347	7.42e-11	59.7	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_19354_1	671143.DAMO_1264	5.33e-29	126.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_13994_1	1033743.CAES01000104_gene3470	5.38e-18	88.6	COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,1TPXH@1239|Firmicutes,4HAKM@91061|Bacilli,26QSE@186822|Paenibacillaceae	91061|Bacilli	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_125584_1	517418.Ctha_2723	3.67e-80	266.0	COG0841@1|root,COG0841@2|Bacteria,1FDQI@1090|Chlorobi	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_101898_1	237368.SCABRO_02014	6.92e-29	118.0	COG2204@1|root,COG2204@2|Bacteria,2IYIG@203682|Planctomycetes	203682|Planctomycetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_101898_2	639282.DEFDS_0186	2e-10	63.5	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_3,PAS,PAS_3,PAS_4,Response_reg
k59_19360_1	400682.PAC_15700744	1.03e-70	229.0	29RJ7@1|root,2RXBE@2759|Eukaryota,39V4K@33154|Opisthokonta,3BJZ7@33208|Metazoa	33208|Metazoa	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4,THAP
k59_101905_2	1192034.CAP_8040	5.09e-26	104.0	2CDCQ@1|root,307SM@2|Bacteria,1QST3@1224|Proteobacteria,4355I@68525|delta/epsilon subdivisions,2WZGF@28221|Deltaproteobacteria,2Z23I@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_72590_1	1313301.AUGC01000005_gene315	1.83e-254	715.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_137424_1	330214.NIDE2491	3.1e-28	112.0	28MYQ@1|root,2ZB5K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_137424_2	459349.CLOAM0027	1.73e-13	68.9	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119700_1	1382359.JIAL01000001_gene1387	1.49e-56	190.0	COG0104@1|root,COG0104@2|Bacteria,3Y2Z9@57723|Acidobacteria,2JIIV@204432|Acidobacteriia	204432|Acidobacteriia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_2146_1	903818.KI912269_gene180	5.55e-24	101.0	28K30@1|root,3359X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184016_1	879212.DespoDRAFT_00289	2.87e-34	132.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_184016_2	1038869.AXAN01000105_gene2883	9.91e-31	115.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria	1224|Proteobacteria	L	PFAM Transposase, Rhodopirellula-type	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_90225_1	7668.SPU_008007-tr	3.66e-77	270.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_26028_1	400682.PAC_15719309	1.88e-68	238.0	KOG1121@1|root,KOG1121@2759|Eukaryota,39RW9@33154|Opisthokonta,3BH13@33208|Metazoa	33208|Metazoa	L	RNA polymerase II regulatory region DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT,zf-BED
k59_55033_1	439292.Bsel_3009	1.93e-30	129.0	COG3780@1|root,COG4626@1|root,COG3780@2|Bacteria,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,26PJM@186821|Sporolactobacillaceae	91061|Bacilli	L	Phage Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
k59_55033_2	755731.Clo1100_1145	7.83e-71	224.0	COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,24CQV@186801|Clostridia,36J76@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_96567_1	697282.Mettu_3710	1.59e-50	183.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1XFZN@135618|Methylococcales	135618|Methylococcales	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_72605_1	269799.Gmet_3477	4.43e-25	108.0	COG2202@1|root,COG3437@1|root,COG3829@1|root,COG3850@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,43UFI@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains Cache_1, HAMP, PAS, PAS	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1
k59_90228_1	7029.ACYPI20089-PA	2.05e-76	246.0	2CN6C@1|root,2QU3U@2759|Eukaryota,38GGN@33154|Opisthokonta,3BC7U@33208|Metazoa,3DKI7@33213|Bilateria,422A5@6656|Arthropoda,3SQP0@50557|Insecta	33208|Metazoa	S	52 kDa repressor of the inhibitor of the protein	Prkrir	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,THAP
k59_113531_1	1122947.FR7_3174	9.19e-86	276.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H2W2@909932|Negativicutes	909932|Negativicutes	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_119713_1	794903.OPIT5_28965	1.88e-09	57.8	COG3682@1|root,COG3682@2|Bacteria,46SZH@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_125633_1	880073.Calab_1878	3.68e-94	290.0	2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78539_1	479433.Caci_5937	1.67e-25	110.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_149057_1	237368.SCABRO_00738	3.59e-34	132.0	COG4467@1|root,COG4467@2|Bacteria,2J4XJ@203682|Planctomycetes	203682|Planctomycetes	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_90236_1	1123236.KB899378_gene1798	1.1e-11	70.9	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,4651Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_119718_1	1379281.AVAG01000009_gene630	5.65e-103	308.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k59_49191_1	41875.XP_007515555.1	7.87e-05	45.4	COG0448@1|root,KOG1504@2759|Eukaryota,37Q6W@33090|Viridiplantae,34H9U@3041|Chlorophyta	3041|Chlorophyta	E	Belongs to the ATCase OTCase family	OTC1	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_37724_2	313625.BL107_06674	2.94e-31	122.0	COG0178@1|root,COG0178@2|Bacteria,1G0KM@1117|Cyanobacteria,1GYXX@1129|Synechococcus	1117|Cyanobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_125636_1	105559.Nwat_1724	9.97e-45	163.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1WWF7@135613|Chromatiales	135613|Chromatiales	H	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_2170_1	378806.STAUR_8051	7.97e-96	298.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YYX2@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_149073_1	252305.OB2597_09304	1.73e-56	195.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,2PCF4@252301|Oceanicola	28211|Alphaproteobacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_90249_1	316055.RPE_0481	1.14e-27	108.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2U5BB@28211|Alphaproteobacteria,3K3YY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_149077_1	227086.JGI_V11_40581	7.03e-33	113.0	2DZEY@1|root,2S6ZB@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154819_1	1379698.RBG1_1C00001G0417	5.29e-49	176.0	COG1198@1|root,COG1198@2|Bacteria,2NNQ3@2323|unclassified Bacteria	2|Bacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_84468_1	568816.Acin_0798	1.22e-17	93.6	COG1629@1|root,COG4771@2|Bacteria,1TQBP@1239|Firmicutes,4H2P2@909932|Negativicutes	909932|Negativicutes	P	TonB-dependent receptor	cirA	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
k59_90265_1	443143.GM18_2882	7.44e-63	209.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria	1224|Proteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k59_101928_3	1122223.KB890702_gene1338	1.1e-19	91.7	COG4322@1|root,COG4322@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF2272
k59_172972_1	985255.APHJ01000030_gene2484	0.000743	47.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.2.1.80,3.4.24.40	ko:K01406,ko:K03332	ko00051,ko01503,map00051,map01503	-	R00879	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_6,F5_F8_type_C,FIVAR,He_PIG,LVIVD,Laminin_G_3,SLH,TSP_3
k59_143345_1	459349.CLOAM0025	1.51e-26	110.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26306_1	318996.AXAZ01000033_gene6428	3.9e-60	201.0	COG1484@1|root,COG4584@1|root,COG1484@2|Bacteria,COG4584@2|Bacteria,1MWQX@1224|Proteobacteria,2TS16@28211|Alphaproteobacteria,3JSGF@41294|Bradyrhizobiaceae	1224|Proteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_96826_1	400682.PAC_15703756	1.92e-64	226.0	COG2801@1|root,KOG0017@2759|Eukaryota,3A0H6@33154|Opisthokonta,3BQ6X@33208|Metazoa	33208|Metazoa	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_184243_1	1379698.RBG1_1C00001G0312	3.14e-70	224.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_31983_1	387631.Asulf_00626	1.06e-17	87.0	COG0475@1|root,arCOG01953@2157|Archaea,2XWTU@28890|Euryarchaeota	28890|Euryarchaeota	P	Kef-type K transport systems, membrane components	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_31983_2	240015.ACP_2713	6.14e-21	91.3	COG1291@1|root,COG1291@2|Bacteria,3Y3Y8@57723|Acidobacteria,2JI9S@204432|Acidobacteriia	204432|Acidobacteriia	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_37985_2	717785.HYPMC_1209	3.23e-22	89.4	2EC8I@1|root,33670@2|Bacteria,1NH09@1224|Proteobacteria,2UKPS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_37985_5	1220589.CD32_00505	2.34e-14	73.6	2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,4HR69@91061|Bacilli	91061|Bacilli	S	YopX protein	-	-	-	-	-	-	-	-	-	-	-	-	YopX
k59_90501_1	1461694.ATO9_11330	3.12e-54	180.0	COG1804@1|root,COG1804@2|Bacteria,1P68A@1224|Proteobacteria,2TR4B@28211|Alphaproteobacteria,2PF6V@252301|Oceanicola	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_90501_2	1156935.QWE_09555	3.48e-26	103.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,4BD58@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_49422_1	1174528.JH992893_gene5951	1.49e-191	608.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
k59_37988_1	7668.SPU_013849-tr	1.11e-75	255.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_149388_1	1173023.KE650771_gene1316	3.33e-10	63.9	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,1GDIN@1117|Cyanobacteria	1117|Cyanobacteria	T	CheW-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,Response_reg
k59_120026_1	1415166.NONO_c22620	5.69e-08	50.1	COG1476@1|root,COG1476@2|Bacteria,2GXMI@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_90503_1	688269.Theth_0169	1.19e-09	60.5	COG0778@1|root,COG1225@1|root,COG0778@2|Bacteria,COG1225@2|Bacteria,2GD2E@200918|Thermotogae	200918|Thermotogae	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Nitroreductase
k59_67177_1	1121022.ABENE_09660	2.41e-44	164.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,2KF7D@204458|Caulobacterales	204458|Caulobacterales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_31996_1	120017.I2FUL9	1.68e-47	172.0	COG0069@1|root,KOG0399@2759|Eukaryota,38E4E@33154|Opisthokonta,3NUMZ@4751|Fungi,3UZFM@5204|Basidiomycota,3N209@452284|Ustilaginomycotina	4751|Fungi	E	Glutamine amidotransferases class-II	GLT1	GO:0001505,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016040,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0017144,GO:0019676,GO:0019740,GO:0019752,GO:0030447,GO:0036267,GO:0040007,GO:0042133,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0065007,GO:0065008,GO:0070783,GO:0071704,GO:0097054,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00264	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,GATase_2,GXGXG,Glu_syn_central,Glu_synthase,Pyr_redox_2
k59_172369_2	344747.PM8797T_19465	2.5e-101	311.0	COG0438@1|root,COG0438@2|Bacteria,2J2RZ@203682|Planctomycetes	203682|Planctomycetes	M	Domain of unknown function (DUF3524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
k59_120033_1	7091.BGIBMGA006564-TA	2.71e-29	112.0	2BNS1@1|root,2S1Q7@2759|Eukaryota,3A48Y@33154|Opisthokonta,3CP8W@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61167_1	1392487.JIAD01000001_gene1488	1.84e-36	140.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,25VPI@186806|Eubacteriaceae	186801|Clostridia	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_61168_1	856793.MICA_276	5.34e-99	309.0	COG0610@1|root,COG0610@2|Bacteria	2|Bacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	Z012_07420	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII,Z1
k59_61168_2	411476.BACOVA_04794	7.52e-20	89.0	COG0863@1|root,COG0863@2|Bacteria,4NF6R@976|Bacteroidetes	976|Bacteroidetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_137677_1	616991.JPOO01000003_gene1995	1.82e-33	132.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,23G9F@178469|Arenibacter	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_19618_2	7029.ACYPI066123-PA	5.8e-161	514.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39MWR@33154|Opisthokonta,3CPGB@33208|Metazoa,3E5ME@33213|Bilateria	2759|Eukaryota	S	Domain of unknown function (DUF4371)	-	-	-	ko:K06515	ko05231,map05231	-	-	-	ko00000,ko00001,ko02000,ko04090	2.A.92.1.1	-	-	Dimer_Tnp_hAT,Exo_endo_phos_2,PRE_C2HC,RVT_1
k59_26341_1	195103.CPF_0474	2.42e-28	121.0	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes,25CRY@186801|Clostridia,36WZU@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_19621_1	517417.Cpar_0386	1.78e-44	157.0	COG1012@1|root,COG1012@2|Bacteria,1FDHS@1090|Chlorobi	1090|Chlorobi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_172402_1	7029.ACYPI41316-PA	1.3e-14	76.3	2CYJA@1|root,2S4S7@2759|Eukaryota,3A62Z@33154|Opisthokonta,3BTAY@33208|Metazoa,3E403@33213|Bilateria	33208|Metazoa	S	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	FLYWCH,MULE
k59_26347_2	526224.Bmur_0881	1.63e-16	80.5	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
k59_120047_1	994573.T472_0215450	4.42e-35	139.0	29DE2@1|root,300BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14391_1	7668.SPU_008679-tr	3.23e-45	166.0	2CMYU@1|root,2QSU3@2759|Eukaryota,38FNT@33154|Opisthokonta,3BK0X@33208|Metazoa,3D503@33213|Bilateria	33208|Metazoa	S	Domain of unknown function (DUF4371)	ZMYM1	GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT,zf-FCS
k59_14396_1	879212.DespoDRAFT_00973	5.53e-56	184.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_184280_1	1379698.RBG1_1C00001G0393	4.99e-100	301.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
k59_184280_2	1419814.V470_06880	1.57e-07	55.1	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli	91061|Bacilli	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_137714_1	309801.trd_1023	4.2e-70	235.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,27XY6@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_2439_1	509635.N824_09565	4.75e-62	210.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
k59_102224_1	324925.Ppha_2533	1.01e-72	235.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_108221_1	7668.SPU_004620-tr	6.22e-26	118.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_172446_1	867903.ThesuDRAFT_01204	1.21e-45	162.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,2495Q@186801|Clostridia,3WD04@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
k59_108238_1	590998.Celf_1537	1.15e-69	238.0	COG3250@1|root,COG5297@1|root,COG3250@2|Bacteria,COG5297@2|Bacteria,2GMQN@201174|Actinobacteria,4F1MZ@85016|Cellulomonadaceae	201174|Actinobacteria	G	PFAM glycoside hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_4_9,CelD_N,Glyco_hydro_9,I-set
k59_167212_1	1379698.RBG1_1C00001G0866	7.79e-96	303.0	COG1674@1|root,COG1674@2|Bacteria,2NNVB@2323|unclassified Bacteria	2|Bacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_32051_1	1121335.Clst_0009	1.5e-53	178.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_67256_2	1123242.JH636436_gene435	2.45e-36	141.0	COG0840@1|root,COG0840@2|Bacteria,2IXQA@203682|Planctomycetes	203682|Planctomycetes	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Globin,HAMP,MCPsignal,PAS_3,PAS_4,PAS_9
k59_131684_1	7668.SPU_017677-tr	3.86e-36	155.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3C1BS@33208|Metazoa,3DJ0V@33213|Bilateria	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_178960_2	411468.CLOSCI_03674	4.76e-35	128.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,21ZVI@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF1949)	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k59_32059_1	7739.XP_002598531.1	4.99e-17	84.3	2DANG@1|root,2TJZW@2759|Eukaryota,39GWZ@33154|Opisthokonta,3CKRG@33208|Metazoa,3DINH@33213|Bilateria	7739.XP_002598531.1|-	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108249_1	290512.Paes_0550	1.48e-18	84.0	COG0205@1|root,COG0205@2|Bacteria,1FEH2@1090|Chlorobi	1090|Chlorobi	G	PFAM phosphofructokinase	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_120693_1	307480.IW16_26445	1.64e-10	68.6	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia,3ZQG3@59732|Chryseobacterium	976|Bacteroidetes	P	Collagen-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_20227_1	768670.Calni_1335	5.08e-14	73.6	COG1580@1|root,COG1580@2|Bacteria,2GFRS@200930|Deferribacteres	200930|Deferribacteres	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_20227_2	522772.Dacet_2850	9.76e-14	71.2	COG1868@1|root,COG1868@2|Bacteria,2GEKC@200930|Deferribacteres	200930|Deferribacteres	N	Flagellar motor switch protein FliM	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_138329_1	1173028.ANKO01000171_gene3836	8.33e-33	132.0	COG0515@1|root,COG2304@1|root,COG0515@2|Bacteria,COG2304@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H7V1@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FGE-sulfatase,Pkinase,TM2,TPR_8,VIT,VWA_3,WD40
k59_120694_2	1123277.KB893177_gene3660	6.54e-30	119.0	COG0726@1|root,COG0726@2|Bacteria,4NKYS@976|Bacteroidetes,47NF6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	pgdA	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_132284_1	4538.ORGLA12G0125000.1	0.000152	42.0	COG0185@1|root,KOG0899@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rps19	GO:0000028,GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006996,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0031974,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0070013,GO:0070925,GO:0071826,GO:0071840,GO:0098798,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22,Ribosomal_L2_C,Ribosomal_S19
k59_161989_1	1121912.AUHD01000026_gene310	3.73e-47	167.0	COG3344@1|root,COG3344@2|Bacteria,4NHMS@976|Bacteroidetes,1HZPH@117743|Flavobacteriia	976|Bacteroidetes	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_161430_2	1415780.JPOG01000001_gene950	7.95e-43	160.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1X78G@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_178980_1	913865.DOT_0731	2.75e-07	59.3	COG0845@1|root,COG0845@2|Bacteria,1UYE5@1239|Firmicutes,24B3X@186801|Clostridia,26017@186807|Peptococcaceae	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_8520_1	935863.AWZR01000002_gene812	8.47e-11	67.4	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,1S0IU@1236|Gammaproteobacteria,1X52Q@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12
k59_120078_1	221109.22778690	1.19e-43	154.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,23JUQ@182709|Oceanobacillus	91061|Bacilli	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k59_155135_1	1121930.AQXG01000005_gene613	3.94e-20	92.4	COG1520@1|root,COG2706@1|root,COG2911@1|root,COG1520@2|Bacteria,COG2706@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	3.1.3.1	ko:K01113,ko:K20274	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	CHU_C,Laminin_G_3,SBBP,VCBS
k59_167249_1	1121459.AQXE01000001_gene2563	2.28e-83	256.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2M8NG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_14466_1	682795.AciX8_2708	0.000107	50.8	COG2972@1|root,COG2972@2|Bacteria,3Y4VK@57723|Acidobacteria,2JP3H@204432|Acidobacteriia	204432|Acidobacteriia	T	histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
k59_67284_1	1173020.Cha6605_5435	3.02e-50	177.0	COG1898@1|root,COG4310@1|root,COG1898@2|Bacteria,COG4310@2|Bacteria,1G39N@1117|Cyanobacteria	1117|Cyanobacteria	M	Domain of unknown function (DUF4910)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
k59_26425_1	330214.NIDE1046	7.09e-50	182.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	barA	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_32091_1	509191.AEDB02000043_gene4764	3.83e-19	85.1	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,3WNBT@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_32091_2	871968.DESME_03400	3.02e-108	325.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_172529_1	1341695.BBOMB_0204	2.04e-33	126.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_8544_1	56780.SYN_02987	1.61e-78	248.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2WQ5S@28221|Deltaproteobacteria,2MRTS@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_2518_1	1123237.Salmuc_02078	1.03e-17	83.6	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2TRPW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_38105_1	224325.AF_0543	3.11e-64	212.0	COG0247@1|root,arCOG00333@2157|Archaea	2157|Archaea	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K18501	-	-	-	-	ko00000	-	-	-	CCG,Fer4_8
k59_38105_2	292459.STH1444	2.06e-43	148.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_38105_3	1121468.AUBR01000038_gene1964	9.81e-10	58.9	COG1280@1|root,COG1280@2|Bacteria,1V725@1239|Firmicutes,24KQ7@186801|Clostridia,42GHE@68295|Thermoanaerobacterales	186801|Clostridia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_2521_1	706587.Desti_1389	5.74e-14	70.1	2DNCW@1|root,32WUD@2|Bacteria,1R39R@1224|Proteobacteria,43DJR@68525|delta/epsilon subdivisions,2X8R0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
k59_143542_1	880072.Desac_1607	1.97e-38	149.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GT	Pyruvate phosphate dikinase PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_113842_1	1237149.C900_02800	1.34e-46	161.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,47K3S@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_2537_1	289376.THEYE_A1789	2.58e-82	263.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
k59_108307_2	1384054.N790_02050	1.09e-10	67.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1X49K@135614|Xanthomonadales	135614|Xanthomonadales	KT	methyl-accepting chemotaxis protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
k59_26446_1	273121.WS0430	6.77e-10	65.9	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_38111_1	585501.HMPREF6123_1859	1.55e-19	90.1	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,2PQSW@265975|Oribacterium	186801|Clostridia	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
k59_84864_1	715226.ABI_39010	5.17e-10	64.7	COG1309@1|root,COG1309@2|Bacteria,1RGCX@1224|Proteobacteria,2UEW7@28211|Alphaproteobacteria,2KI8Q@204458|Caulobacterales	204458|Caulobacterales	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
k59_120125_2	319225.Plut_1089	5.68e-37	139.0	COG0046@1|root,COG0046@2|Bacteria,1FDFR@1090|Chlorobi	1090|Chlorobi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_43566_1	1379698.RBG1_1C00001G0584	6.41e-78	265.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
k59_113846_1	4577.GRMZM2G431033_P01	1.8e-20	96.3	28HC0@1|root,2QPQD@2759|Eukaryota,37QN4@33090|Viridiplantae,3GWPH@35493|Streptophyta,3M32A@4447|Liliopsida,3IKMK@38820|Poales	35493|Streptophyta	S	Zinc finger MYM-type protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4371,Dimer_Tnp_hAT
k59_38114_1	1245471.PCA10_p1450	7.33e-89	268.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1YE8I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	IstB-like ATP binding protein	istB3	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_8590_1	1278073.MYSTI_05251	1.44e-87	266.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_184431_1	706587.Desti_4206	1.4e-20	89.7	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
k59_14515_1	96561.Dole_1480	1.71e-71	233.0	COG1032@1|root,COG1032@2|Bacteria,1RJ9Z@1224|Proteobacteria,42TDD@68525|delta/epsilon subdivisions,2WPHS@28221|Deltaproteobacteria,2MK5Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Radical_SAM
k59_102332_1	589865.DaAHT2_1078	3.01e-48	166.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42UAY@68525|delta/epsilon subdivisions,2X5BX@28221|Deltaproteobacteria,2MQ2T@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
k59_79008_1	246197.MXAN_4473	1.98e-61	197.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
k59_102333_1	1519464.HY22_13970	1.56e-39	142.0	COG1216@1|root,COG1216@2|Bacteria,1FF4F@1090|Chlorobi	1090|Chlorobi	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_167310_1	7029.ACYPI39283-PA	9.59e-28	122.0	2CXYR@1|root,2S0S7@2759|Eukaryota,39ZC1@33154|Opisthokonta,3BG55@33208|Metazoa,3CZ2K@33213|Bilateria,422NS@6656|Arthropoda,3SRBE@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
k59_26472_1	1094980.Mpsy_0036	5.16e-38	133.0	COG2249@1|root,arCOG02577@2157|Archaea,2XT8P@28890|Euryarchaeota,2NARU@224756|Methanomicrobia	224756|Methanomicrobia	H	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
k59_84890_2	1303518.CCALI_02735	1.8e-47	166.0	COG1220@1|root,COG1220@2|Bacteria	2|Bacteria	O	peptidase activity, acting on L-amino acid peptides	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_97013_1	330214.NIDE2490	1.75e-21	94.0	29ZH8@1|root,30MGZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_161529_5	1235788.C802_02967	1.92e-22	93.6	COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes,2FWKI@200643|Bacteroidia	976|Bacteroidetes	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109264_1	1410638.JHXJ01000024_gene810	1.32e-57	199.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WGJP@541000|Ruminococcaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_109264_2	1173025.GEI7407_2130	6.92e-12	63.9	COG1238@1|root,COG1238@2|Bacteria,1G75P@1117|Cyanobacteria,1HFMF@1150|Oscillatoriales	1117|Cyanobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_85736_1	281687.CJA14732	3.6e-13	83.2	KOG1075@1|root,KOG1473@1|root,KOG1075@2759|Eukaryota,KOG1473@2759|Eukaryota,38G7R@33154|Opisthokonta,3BB4Y@33208|Metazoa,3CVMZ@33213|Bilateria,40C8C@6231|Nematoda,1KV55@119089|Chromadorea,40YG5@6236|Rhabditida	33208|Metazoa	K	domain in different transcription and chromosome remodeling factors	BPTF	GO:0000003,GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0002165,GO:0002376,GO:0002520,GO:0002682,GO:0002683,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006325,GO:0006338,GO:0006351,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007283,GO:0007399,GO:0007417,GO:0007420,GO:0008134,GO:0008150,GO:0008152,GO:0008593,GO:0009058,GO:0009059,GO:0009719,GO:0009725,GO:0009755,GO:0009791,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0014070,GO:0016043,GO:0016070,GO:0016589,GO:0016922,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030097,GO:0030154,GO:0030518,GO:0030522,GO:0031010,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031348,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032774,GO:0032870,GO:0032991,GO:0033993,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0035064,GO:0035073,GO:0035075,GO:0035076,GO:0035210,GO:0035257,GO:0036314,GO:0036315,GO:0042221,GO:0042393,GO:0042766,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043401,GO:0043565,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0045088,GO:0045747,GO:0045824,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046425,GO:0046426,GO:0046483,GO:0048232,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051427,GO:0051704,GO:0051716,GO:0060255,GO:0060322,GO:0065007,GO:0070013,GO:0070577,GO:0070603,GO:0070887,GO:0071310,GO:0071383,GO:0071390,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097305,GO:0097306,GO:0097659,GO:0140030,GO:0140033,GO:0140034,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1904892,GO:1904893,GO:1904949,GO:2000112,GO:2000113,GO:2001141	-	ko:K11728	-	-	-	-	ko00000,ko03036	-	-	-	Bromodomain,DDT,PHD,WHIM1,WSD
k59_32887_1	706587.Desti_5255	3.66e-103	338.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MR5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_32887_2	882378.RBRH_01230	9.29e-22	89.7	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2VR2H@28216|Betaproteobacteria,1K79Y@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_96510_1	7668.SPU_008020-tr	1.83e-30	125.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,RVT_1
k59_143048_1	1121035.AUCH01000005_gene11	2.01e-06	55.1	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria	1224|Proteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
k59_43160_1	1121439.dsat_1283	1.88e-53	186.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2MG45@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_84991_1	485915.Dret_2212	3.02e-95	291.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2M86R@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_102438_1	1101190.ARWB01000001_gene2768	0.000313	45.8	COG1595@1|root,COG1595@2|Bacteria,1RKMN@1224|Proteobacteria,2U9GS@28211|Alphaproteobacteria,370J3@31993|Methylocystaceae	28211|Alphaproteobacteria	K	ECF sigma factor	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_131884_1	269799.Gmet_2743	7.91e-18	90.1	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6,Peptidase_S8,TIG
k59_97129_1	1321786.HMPREF1992_00556	5.51e-14	72.8	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4H2V3@909932|Negativicutes	909932|Negativicutes	N	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_97129_2	1125863.JAFN01000001_gene699	1.06e-14	77.4	COG1317@1|root,COG1317@2|Bacteria,1NJAJ@1224|Proteobacteria,42P5I@68525|delta/epsilon subdivisions,2WSGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k59_184538_1	59689.Al_scaffold_0002_964	4.97e-32	112.0	2C06H@1|root,2S7KE@2759|Eukaryota,37X2N@33090|Viridiplantae,3GM7I@35493|Streptophyta	35493|Streptophyta	S	Photosystem II reaction center protein Z	psbZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02724	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	Ycf9
k59_184538_2	4572.TRIUR3_00075-P1	0.0	958.0	28ISP@1|root,2QR3X@2759|Eukaryota,37T53@33090|Viridiplantae,3G7SE@35493|Streptophyta,3KP6W@4447|Liliopsida,3IG0F@38820|Poales	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbC	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_184538_3	3880.AES88236	2.52e-255	717.0	28ISP@1|root,2QR3X@2759|Eukaryota,37T53@33090|Viridiplantae,3G7SE@35493|Streptophyta,4JVU0@91835|fabids	35493|Streptophyta	P	Photosystem II CP43 chlorophyll apoprotein	-	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII,Photo_RC
k59_2717_1	671143.DAMO_2304	2.23e-65	219.0	COG0769@1|root,COG0769@2|Bacteria,2NNZM@2323|unclassified Bacteria	2|Bacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	3.4.16.4,6.3.2.10,6.3.2.13	ko:K01928,ko:K03587,ko:K15792	ko00300,ko00550,ko01501,map00300,map00550,map01501	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iNJ661.Rv2158c,iWFL_1372.ECW_m0084,ic_1306.c0103	DUF1727,Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_179174_1	354242.CJJ81176_0672	8.78e-34	126.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_179174_2	227377.CBU_1982	4.97e-26	106.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1JC5Q@118969|Legionellales	118969|Legionellales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_73148_1	96561.Dole_2516	1.75e-59	212.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2MHTD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_155330_1	373903.Hore_10390	7.51e-25	101.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WAMU@53433|Halanaerobiales	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_155330_2	1122216.AUHW01000038_gene258	7.24e-35	129.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4H4EK@909932|Negativicutes	909932|Negativicutes	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_61380_1	107636.JQNK01000008_gene4069	1.99e-12	63.9	COG4456@1|root,COG4456@2|Bacteria,1N06P@1224|Proteobacteria,2UEZJ@28211|Alphaproteobacteria,370IJ@31993|Methylocystaceae	28211|Alphaproteobacteria	S	SpoVT / AbrB like domain	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
k59_61380_2	1453503.AU05_22330	1e-12	67.0	COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,1SAJG@1236|Gammaproteobacteria,1YKEJ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
k59_137993_1	59374.Fisuc_2776	6.97e-37	135.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,YojJ
k59_38231_1	391037.Sare_0942	5.44e-42	149.0	28HRJ@1|root,2Z7YZ@2|Bacteria,2GKNT@201174|Actinobacteria,4D982@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14653_1	1121403.AUCV01000081_gene3760	1.16e-46	151.0	COG2161@1|root,COG2161@2|Bacteria,1N63R@1224|Proteobacteria,42TVZ@68525|delta/epsilon subdivisions,2WQRE@28221|Deltaproteobacteria,2MKSX@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_14653_2	1047013.AQSP01000142_gene177	2.29e-45	147.0	COG3668@1|root,COG3668@2|Bacteria,2NRM7@2323|unclassified Bacteria	2|Bacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_113931_2	378806.STAUR_1465	0.000344	48.1	COG0454@1|root,COG0456@2|Bacteria,1R7PK@1224|Proteobacteria	1224|Proteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_102456_1	879212.DespoDRAFT_00661	3.73e-52	173.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_167477_1	10224.XP_006815646.1	7.1e-32	121.0	2AHQR@1|root,2RZ2Y@2759|Eukaryota,3A29J@33154|Opisthokonta,3BS9C@33208|Metazoa,3DCSK@33213|Bilateria	33208|Metazoa	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_61401_1	187272.Mlg_0280	1.91e-23	102.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales	135613|Chromatiales	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_61401_2	553178.CAPGI0001_2547	0.000174	47.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,1EQCP@1016|Capnocytophaga	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
k59_43698_1	10224.XP_002731860.1	3.36e-51	177.0	29RJ7@1|root,2RXBE@2759|Eukaryota,39V4K@33154|Opisthokonta,3BJZ7@33208|Metazoa,3D3HW@33213|Bilateria	33208|Metazoa	S	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4,THAP
k59_85039_1	8153.XP_005952760.1	1.13e-32	128.0	KOG1121@1|root,KOG1121@2759|Eukaryota,3AFZ1@33154|Opisthokonta,3BZKR@33208|Metazoa,3DEPD@33213|Bilateria,48IPR@7711|Chordata,49ETW@7742|Vertebrata,4A6D4@7898|Actinopterygii	33208|Metazoa	L	zinc finger BED domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF659,Dimer_Tnp_hAT
k59_97163_1	400682.PAC_15725343	2.86e-50	191.0	2D43P@1|root,2STRT@2759|Eukaryota,3AAAX@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_8749_1	1123372.AUIT01000004_gene1184	2.44e-55	194.0	COG0187@1|root,COG0187@2|Bacteria,2GH3W@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_14670_1	1379698.RBG1_1C00001G1473	1.31e-64	211.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha
k59_161677_1	220664.PFL_2855	3.58e-11	67.4	COG3637@1|root,COG3637@2|Bacteria,1R94P@1224|Proteobacteria,1T0SQ@1236|Gammaproteobacteria,1YQWM@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_161679_1	797299.HALLA_07945	3.69e-26	112.0	COG0534@1|root,arCOG01731@2157|Archaea,2XU54@28890|Euryarchaeota,23SKQ@183963|Halobacteria	183963|Halobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_149754_1	158190.SpiGrapes_0781	1.93e-17	81.3	COG2309@1|root,COG2309@2|Bacteria,2J6N5@203691|Spirochaetes	203691|Spirochaetes	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k59_26611_1	671143.DAMO_1653	1.05e-10	69.7	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_149755_1	1121447.JONL01000013_gene3711	7.77e-18	83.2	COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,42R2Q@68525|delta/epsilon subdivisions,2WP6F@28221|Deltaproteobacteria,2MA79@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k59_131954_1	7668.SPU_028383-tr	1.33e-58	214.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BHS6@33208|Metazoa,3E42R@33213|Bilateria	33208|Metazoa	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve,zf-CCHC
k59_73181_1	573413.Spirs_1593	8.97e-79	253.0	COG0488@1|root,COG0488@2|Bacteria,2J5VJ@203691|Spirochaetes	203691|Spirochaetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_126190_1	1267535.KB906767_gene2215	1.15e-32	128.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_79192_1	1116472.MGMO_74c00110	3.02e-46	152.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_79192_2	933262.AXAM01000020_gene47	3.95e-08	50.4	COG1598@1|root,COG1598@2|Bacteria,1NC35@1224|Proteobacteria,42VAZ@68525|delta/epsilon subdivisions,2WSCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55704_2	744979.R2A130_1182	1.21e-49	172.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_179214_1	742741.HMPREF9475_01259	1e-11	63.5	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,21ZZ0@1506553|Lachnoclostridium	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_61448_3	358681.BBR47_29040	8.47e-26	108.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,4HNK6@91061|Bacilli	91061|Bacilli	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2,Phg_2220_C
k59_131978_2	1237149.C900_01592	8.21e-33	129.0	295M7@1|root,2ZSYM@2|Bacteria,4NNH9@976|Bacteroidetes,47UGS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_90835_2	1379698.RBG1_1C00001G1127	7.28e-27	108.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_102511_1	7029.ACYPI22533-PA	5.87e-06	48.5	KOG3371@1|root,2S78S@2759|Eukaryota,3AAR8@33154|Opisthokonta,3BUXM@33208|Metazoa,3DAVV@33213|Bilateria,422VW@6656|Arthropoda	33208|Metazoa	S	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	THAP,Tnp_P_element
k59_97219_1	243159.AFE_0836	2.16e-51	168.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,1RYKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_43753_1	1379698.RBG1_1C00001G0964	1.44e-23	94.7	COG2050@1|root,COG2050@2|Bacteria,2NQ0Q@2323|unclassified Bacteria	2|Bacteria	Q	Thioesterase superfamily	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
## 2808 queries scanned
## Total time (seconds): 73.4343752861023
## Rate: 38.24 q/s