## Sat Jan  4 06:16:22 2025
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA629394/SRR11734698/SRR11734698_p_cluster_rep_seq.fasta --output PRJNA629394_SRR11734698 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k59_224565_1	765913.ThidrDRAFT_1278	7.68e-88	273.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,1WVZB@135613|Chromatiales	135613|Chromatiales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_224565_2	395494.Galf_0076	8.95e-35	132.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,44W4X@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_15637_1	537013.CLOSTMETH_03821	4.04e-21	95.5	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,3WHJG@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-rhamnosidase N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,FIVAR
k59_62106_1	1168034.FH5T_15080	1.85e-50	170.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,2FSAZ@200643|Bacteroidia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_240026_1	1165841.SULAR_06613	1.82e-108	318.0	COG4654@1|root,COG4654@2|Bacteria,1R1K5@1224|Proteobacteria,42WVZ@68525|delta/epsilon subdivisions,2YQRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_240026_2	436114.SYO3AOP1_1768	2.23e-18	80.5	COG2703@1|root,COG2703@2|Bacteria,2G48F@200783|Aquificae	200783|Aquificae	P	TIGRFAM hemerythrin-like metal-binding protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_85281_1	1121933.AUHH01000019_gene2432	3.67e-08	58.9	COG0469@1|root,COG0469@2|Bacteria,2H57R@201174|Actinobacteria	201174|Actinobacteria	G	Pyruvate kinase	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
k59_85281_2	313596.RB2501_10177	3.74e-14	68.9	COG0668@1|root,COG0668@2|Bacteria,4NP36@976|Bacteroidetes,1I1XC@117743|Flavobacteriia	976|Bacteroidetes	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_7932_1	1201293.AKXQ01000004_gene2282	4.62e-60	202.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alkaline phosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_85286_1	411467.BACCAP_04249	2.92e-46	166.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,267Y3@186813|unclassified Clostridiales	186801|Clostridia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k59_38884_1	313596.RB2501_05190	1.32e-61	200.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_100750_2	870187.Thini_1135	5.86e-26	101.0	2CHMD@1|root,330HB@2|Bacteria,1QTRE@1224|Proteobacteria,1SFBW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
k59_147150_1	1028800.RG540_CH23010	2.24e-24	105.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,4B8P1@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_216858_1	765911.Thivi_3136	3.03e-41	146.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales	135613|Chromatiales	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_216858_2	2340.JV46_24750	4.56e-92	277.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k59_31243_1	1355368.JART01000015_gene1942	1.32e-34	137.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2YN67@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD,Prok-TraM
k59_178174_1	1049564.TevJSym_aq00430	1.19e-33	121.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1J6DN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	OSCP
k59_178174_2	2340.JV46_17410	1.53e-35	132.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_170436_1	1047013.AQSP01000114_gene705	6.2e-88	269.0	COG3385@1|root,COG3385@2|Bacteria,2NQNF@2323|unclassified Bacteria	2|Bacteria	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_69822_1	882.DVU_0360	2.44e-79	256.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42MV2@68525|delta/epsilon subdivisions,2WJ7U@28221|Deltaproteobacteria,2M839@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_7938_1	404589.Anae109_0505	4.32e-38	137.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_69823_1	1519464.HY22_07470	4.79e-09	55.5	COG0669@1|root,COG0669@2|Bacteria,1FDW6@1090|Chlorobi	1090|Chlorobi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_69823_2	998674.ATTE01000001_gene2472	8.67e-50	166.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,4602A@72273|Thiotrichales	72273|Thiotrichales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_199_1	550540.Fbal_3033	1.04e-71	229.0	COG0786@1|root,COG0786@2|Bacteria,1MVBC@1224|Proteobacteria,1RP0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
k59_178177_2	1173024.KI912148_gene3276	1.16e-07	50.1	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
k59_100755_1	986075.CathTA2_0420	7.31e-32	127.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_232332_1	1163617.SCD_n00183	1.63e-83	259.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_77521_1	395493.BegalDRAFT_2923	1.01e-183	549.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,461Q7@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_15648_1	1168034.FH5T_03100	2.89e-82	257.0	COG2000@1|root,COG2221@1|root,COG4624@1|root,COG2000@2|Bacteria,COG2221@2|Bacteria,COG4624@2|Bacteria,4NJAS@976|Bacteroidetes,2FMHZ@200643|Bacteroidia	976|Bacteroidetes	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_6
k59_178182_1	1538295.JY96_11020	8.02e-31	113.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_178182_2	1177179.A11A3_12028	7.3e-20	83.6	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria,1XM9P@135619|Oceanospirillales	135619|Oceanospirillales	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
k59_216875_1	1123070.KB899259_gene1978	2.03e-25	110.0	COG0823@1|root,COG0823@2|Bacteria,46TMC@74201|Verrucomicrobia,2IVG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232338_1	2340.JV46_13500	4.71e-38	140.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1J5CM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_232338_2	2340.JV46_13020	6.6e-76	238.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1J5A7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the thiolase family	yqeF	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034308,GO:0034309,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046165,GO:0046395,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:0072329,GO:1901575,GO:1901576,GO:1901615,GO:1901617	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSSON_1240.SSON_3004	Thiolase_C,Thiolase_N
k59_93096_1	1198232.CYCME_0158	2.62e-14	72.4	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,460RQ@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_123895_1	247634.GPB2148_1760	2.83e-90	275.0	2DB8I@1|root,2Z7RY@2|Bacteria,1MY4M@1224|Proteobacteria,1SPR1@1236|Gammaproteobacteria,1JAR1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131737_1	1158345.JNLL01000001_gene1125	5.17e-26	101.0	COG4636@1|root,COG4636@2|Bacteria,2G3YN@200783|Aquificae	200783|Aquificae	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_147163_2	1121015.N789_08325	8.33e-81	251.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1SYRP@1236|Gammaproteobacteria,1XCVH@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_123903_2	1168034.FH5T_11960	1.3e-111	325.0	COG4122@1|root,COG4122@2|Bacteria,4NNYP@976|Bacteroidetes	976|Bacteroidetes	M	tRNA methyltransferase complex GCD14 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
k59_212_1	56780.SYN_00869	3.08e-73	238.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions,2WK7W@28221|Deltaproteobacteria,2MQ9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	MOFRL family	Glyctk	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
k59_201358_1	387093.SUN_0132	2.83e-05	45.4	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_201358_2	1165841.SULAR_10359	3.59e-37	127.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2YP65@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_116250_1	1168034.FH5T_07970	9.18e-177	497.0	28NPZ@1|root,2ZBPQ@2|Bacteria,4NN3K@976|Bacteroidetes,2FPEH@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_15658_1	396588.Tgr7_0109	8.57e-25	99.4	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exodeoxyribonuclease III	crc	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_15658_2	1219375.CM002139_gene3769	4.64e-32	117.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1X3TD@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_54404_1	7425.NV18822-PA	8.49e-11	63.5	COG2801@1|root,KOG0017@2759|Eukaryota,39ZX7@33154|Opisthokonta,3BQ45@33208|Metazoa	33208|Metazoa	H	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_23398_1	1165841.SULAR_05558	1.2e-136	395.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_23398_2	1165841.SULAR_05553	5.34e-89	267.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_93121_1	1219065.VPR01S_04_02900	5.64e-21	87.4	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1XWYF@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_178190_2	1328313.DS2_05260	0.00027	44.3	COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1S8X3@1236|Gammaproteobacteria,4676M@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	epsM	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k59_139591_1	314278.NB231_12259	1.01e-83	275.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_147181_1	2340.JV46_26640	1.51e-82	271.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_116258_1	1255043.TVNIR_0728	8.45e-25	101.0	COG1396@1|root,COG1396@2|Bacteria,1N3RQ@1224|Proteobacteria,1S3WE@1236|Gammaproteobacteria,1X0XP@135613|Chromatiales	135613|Chromatiales	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K13655	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	MqsA_antitoxin
k59_100791_1	1165841.SULAR_01818	3.12e-119	347.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_162645_1	1122179.KB890416_gene2641	2.99e-97	316.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IQBJ@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_216894_1	1406840.Q763_09620	2.38e-12	69.7	COG1167@1|root,COG1167@2|Bacteria,4NGKQ@976|Bacteroidetes,1I02W@117743|Flavobacteriia,2NT2S@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	yjiR	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_209122_1	1118054.CAGW01000010_gene3951	9.43e-40	149.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes	1239|Firmicutes	KT	Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PocR,Sigma54_activat
k59_147201_1	1382359.JIAL01000001_gene1917	1.8e-07	53.5	COG1091@1|root,COG1091@2|Bacteria,3Y3IG@57723|Acidobacteria,2JIEX@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_201363_1	857087.Metme_1705	4.93e-35	122.0	COG4453@1|root,COG4453@2|Bacteria,1PW10@1224|Proteobacteria,1TEV8@1236|Gammaproteobacteria,1XGWH@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
k59_162648_1	56780.SYN_00410	3.51e-12	65.5	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQE7@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_162648_2	56780.SYN_00409	6.36e-38	141.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WKQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_170468_1	794903.OPIT5_28630	1.36e-08	62.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CBM_6,Glyco_hydro_16,VCBS
k59_154993_1	71139.XP_010041504.1	7.7e-22	94.7	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta	35493|Streptophyta	L	DNA RNA polymerases superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Chromo,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_154993_2	4098.XP_009586987.1	1.45e-67	230.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta,44P0E@71274|asterids	35493|Streptophyta	L	DNA RNA polymerases superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,RVT_1,Retrotrans_gag
k59_116267_1	1165841.SULAR_03272	1.11e-114	338.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42QKD@68525|delta/epsilon subdivisions,2YNHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein	sorA	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_131774_1	1265313.HRUBRA_00889	1.61e-26	103.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_131774_2	1265313.HRUBRA_00890	2.38e-45	147.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_240064_1	2340.JV46_06860	8.51e-59	194.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1J58A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0826 Collagenase and related proteases	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_240064_2	768671.ThimaDRAFT_1126	4.86e-25	105.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales	135613|Chromatiales	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
k59_224615_2	247634.GPB2148_462	9.36e-85	264.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1J88Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_77544_1	1165841.SULAR_05708	1.88e-92	277.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2YMRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_151888_1	886377.Murru_1521	3.4e-42	142.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,1I4NU@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB
k59_151888_2	1004149.AFOE01000029_gene2835	2.76e-78	242.0	COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes,1HYV9@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_113273_1	765912.Thimo_3624	6.71e-74	236.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales	135613|Chromatiales	S	PFAM Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_206075_2	1168034.FH5T_04700	1.34e-36	132.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_51300_1	1210884.HG799467_gene13149	6.9e-42	154.0	COG1680@1|root,COG1680@2|Bacteria,2IWSU@203682|Planctomycetes	203682|Planctomycetes	MV	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_43674_2	1036674.A28LD_0585	2.94e-21	89.7	COG0625@1|root,COG0625@2|Bacteria,1RDBD@1224|Proteobacteria,1TDD0@1236|Gammaproteobacteria,2QG7K@267893|Idiomarinaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
k59_5129_1	1123057.P872_12995	5.87e-39	142.0	COG2367@1|root,COG2367@2|Bacteria,4PMKC@976|Bacteroidetes,47JSP@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
k59_74646_1	391615.ABSJ01000042_gene2284	5.49e-21	98.6	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1J4BX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_82318_1	1165841.SULAR_10409	8.02e-176	496.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2YMZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_144676_1	1165841.SULAR_04542	8.56e-87	267.0	COG1538@1|root,COG1538@2|Bacteria,1PBTH@1224|Proteobacteria,42R59@68525|delta/epsilon subdivisions,2YP2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_43677_1	1121440.AUMA01000009_gene593	1.99e-48	176.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2M832@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_82319_1	1168034.FH5T_16715	3.27e-65	206.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,2FPCK@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
k59_229188_1	998674.ATTE01000001_gene4560	4.16e-38	142.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,1RPFC@1236|Gammaproteobacteria,463KS@72273|Thiotrichales	72273|Thiotrichales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_136434_1	1165841.SULAR_09194	3.14e-61	192.0	COG0526@1|root,COG0526@2|Bacteria,1Q2Q0@1224|Proteobacteria,42W2S@68525|delta/epsilon subdivisions,2YQBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_151905_1	555779.Dthio_PD0436	5.72e-42	153.0	COG1373@1|root,COG1373@2|Bacteria,1MWDX@1224|Proteobacteria,42Q61@68525|delta/epsilon subdivisions,2WM4W@28221|Deltaproteobacteria,2MG0J@213115|Desulfovibrionales	555779.Dthio_PD0436|-	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144681_1	1484460.JSWG01000009_gene71	4.16e-16	75.5	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia	976|Bacteroidetes	S	UDP-2,3-diacylglucosamine hydrolase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
k59_144681_2	313596.RB2501_07445	7.73e-88	259.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,1I173@117743|Flavobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_144681_3	1353276.JADR01000002_gene2318	2.39e-13	68.9	COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,1HWUU@117743|Flavobacteriia	976|Bacteroidetes	O	proline hydroxylase	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
k59_237250_2	96561.Dole_1285	3.93e-56	183.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2MJQ5@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	PFAM ABC transporter	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_190798_1	1123276.KB893283_gene5125	7.06e-26	108.0	COG2114@1|root,COG2909@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,4PPRT@976|Bacteroidetes	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_74654_1	1051501.AYTL01000004_gene3773	1.63e-29	115.0	COG5634@1|root,COG5634@2|Bacteria,1UESK@1239|Firmicutes,4HESW@91061|Bacilli,1ZG7X@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2278)	yukJ	-	-	-	-	-	-	-	-	-	-	-	DUF2278
k59_190799_1	1121875.KB907550_gene868	1.11e-74	234.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia	976|Bacteroidetes	EJ	GlutRNAGln amidotransferase subunit D	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_190799_2	1121875.KB907550_gene869	3.52e-85	258.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_167728_1	1165841.SULAR_06223	1.21e-199	573.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_198649_1	2340.JV46_21910	5.27e-48	175.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T216@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
k59_198649_2	1499967.BAYZ01000088_gene5073	2.61e-06	48.9	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	arcB	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07648	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_89994_2	998674.ATTE01000001_gene1059	1.37e-42	149.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,4612H@72273|Thiotrichales	72273|Thiotrichales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_144690_1	1049564.TevJSym_av00520	9.27e-15	74.7	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_105417_1	3880.AES58602	8.54e-37	137.0	COG1005@1|root,COG3344@1|root,KOG4768@2759|Eukaryota,KOG4770@2759|Eukaryota,37KUX@33090|Viridiplantae,3GHBI@35493|Streptophyta,4JTJX@91835|fabids	35493|Streptophyta	A	NADH dehydrogenase (quinone) activity	matR	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2
k59_190800_1	1123355.JHYO01000013_gene1150	9.16e-91	278.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,36X6V@31993|Methylocystaceae	28211|Alphaproteobacteria	F	IMP dehydrogenase / GMP reductase domain	-	-	-	-	-	-	-	-	-	-	-	-	IMPDH
k59_175026_1	266748.HY04_00840	1.42e-56	202.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia,3ZQX9@59732|Chryseobacterium	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_121385_1	481448.Minf_2107	1.64e-07	54.7	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia,37GFD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
k59_121385_2	2340.JV46_23540	8.41e-36	129.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1J6CF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_0125,iPC815.YPO3411,iSDY_1059.SDY_0028	Spermine_synt_N,Spermine_synth
k59_105418_1	880071.Fleli_0341	1.49e-50	178.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47MSQ@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_221629_1	1165841.SULAR_04172	9.05e-108	327.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_43706_1	1165841.SULAR_09654	1.02e-25	99.4	COG5615@1|root,COG5615@2|Bacteria,1Q1KK@1224|Proteobacteria,42TX3@68525|delta/epsilon subdivisions,2YPV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43706_2	1165841.SULAR_09649	4.4e-55	176.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_82333_1	1265503.KB905160_gene2819	3.53e-86	278.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	4.2.2.23	ko:K06972,ko:K18195	-	-	-	-	ko00000,ko01000,ko01002	-	PL4	-	Autotransporter,CBM-like,DUF285,Flg_new,SLH,fn3_3
k59_229205_2	1165841.SULAR_02948	2.27e-81	255.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_175033_1	760192.Halhy_4779	5.95e-07	50.8	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
k59_175033_2	391625.PPSIR1_12348	1.54e-60	189.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2YVK9@29|Myxococcales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_144707_1	313596.RB2501_02320	7.64e-122	368.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_167744_2	1408473.JHXO01000006_gene1315	7.3e-30	112.0	COG0500@1|root,COG2226@2|Bacteria,4PHN8@976|Bacteroidetes,2FVJG@200643|Bacteroidia	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67092_1	156889.Mmc1_0648	2.23e-35	135.0	COG3372@1|root,COG3372@2|Bacteria,1NVX4@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
k59_221638_1	574966.KB898646_gene3214	1.45e-98	318.0	COG5114@1|root,COG5114@2|Bacteria,1QV7J@1224|Proteobacteria,1T3X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	B	positive regulation of histone acetylation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_167747_1	1121921.KB898716_gene9	2.11e-50	166.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,2PNHB@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	K	Uncharacterized ACR, COG1678	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_167747_2	472759.Nhal_0211	1.44e-16	75.1	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1WYAH@135613|Chromatiales	135613|Chromatiales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_36210_1	1197906.CAJQ02000034_gene2807	0.000592	39.3	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UFPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_36210_2	2340.JV46_09700	3.91e-48	162.0	COG3448@1|root,COG3448@2|Bacteria,1QUQ5@1224|Proteobacteria,1T20R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_105445_1	1165841.SULAR_06978	2.16e-103	301.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2YP7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_105445_2	1165841.SULAR_06983	1.56e-106	308.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2YT8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_121412_1	572480.Arnit_0213	1.73e-118	344.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2YM7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
k59_113333_1	4113.PGSC0003DMT400091476	1.68e-20	88.2	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,44TGH@71274|asterids	35493|Streptophyta	J	MatK/TrnK amino terminal region	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_167752_1	1168034.FH5T_08640	1.82e-82	251.0	28NZ3@1|root,2ZBW2@2|Bacteria,4NN5U@976|Bacteroidetes,2FKZ5@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_229210_1	1121022.ABENE_11320	1.85e-32	128.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	ko:K02014,ko:K15721	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.7.2	-	-	Plug,TonB_dep_Rec
k59_145246_3	161156.JQKW01000001_gene1449	3.54e-50	174.0	COG0374@1|root,COG0374@2|Bacteria,2GH4N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_214398_1	1123401.JHYQ01000022_gene1140	2.07e-55	186.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,45ZWE@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_191297_1	436717.AOLE_06685	1.79e-72	228.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,3NIQG@468|Moraxellaceae	1236|Gammaproteobacteria	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K07506,ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k59_20828_1	395493.BegalDRAFT_1423	7.11e-66	211.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,45ZMY@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_129452_1	616991.JPOO01000003_gene1166	2.44e-65	208.0	COG0526@1|root,COG0526@2|Bacteria,4NMNR@976|Bacteroidetes,1IJ9P@117743|Flavobacteriia,23FXF@178469|Arenibacter	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369
k59_129452_2	313603.FB2170_16101	4.57e-18	77.8	2E43R@1|root,32Z02@2|Bacteria,4NVFS@976|Bacteroidetes,1I51B@117743|Flavobacteriia,2PHST@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44225_1	1216967.L100_13879	1.63e-72	228.0	COG3677@1|root,COG3677@2|Bacteria,4NPDE@976|Bacteroidetes,1I5ER@117743|Flavobacteriia	976|Bacteroidetes	L	Protein involved in DNA binding, transposase activity and transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,Transposase_mut
k59_191301_1	857087.Metme_0224	4.25e-80	244.0	COG5285@1|root,COG5285@2|Bacteria,1R9W1@1224|Proteobacteria,1S7VN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k59_105832_1	1121405.dsmv_0430	1.61e-73	229.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_168292_1	1049564.TevJSym_ak00530	4.74e-46	166.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1J5FJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0038 Chloride channel protein EriC	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
k59_145258_2	387093.SUN_1884	1.43e-15	70.5	2DHPI@1|root,300H7@2|Bacteria,1Q6A9@1224|Proteobacteria,432QM@68525|delta/epsilon subdivisions,2YSHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129458_1	1165841.SULAR_05493	8.54e-126	367.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_151991_2	1191523.MROS_0164	9.41e-40	141.0	COG0002@1|root,COG0002@2|Bacteria	2|Bacteria	E	N-acetyl-gamma-glutamyl-phosphate reductase activity	argC	-	1.2.1.38	ko:K00145,ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00028,M00031,M00763,M00845	R03443,R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_221652_1	1274.HX89_02920	3.2e-22	102.0	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria,1ZX6M@145357|Dermacoccaceae	201174|Actinobacteria	L	ATP-dependent helicase C-terminal	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_97938_1	1121957.ATVL01000009_gene867	1.19e-25	110.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,47M3M@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
k59_12664_1	1298867.AUES01000066_gene4685	8.87e-34	133.0	COG1572@1|root,COG1572@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
k59_59145_1	159087.Daro_3903	1.46e-40	137.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2VU3F@28216|Betaproteobacteria,2KXAS@206389|Rhodocyclales	206389|Rhodocyclales	P	Small Multidrug Resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
k59_59147_1	118173.KB235914_gene1400	4.17e-30	124.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k59_144763_1	1168034.FH5T_12715	8.68e-84	266.0	COG0369@1|root,COG0369@2|Bacteria,4NHR8@976|Bacteroidetes,2FR5G@200643|Bacteroidia	976|Bacteroidetes	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
k59_152005_1	1232437.KL661983_gene3538	1.71e-36	135.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,42SGW@68525|delta/epsilon subdivisions,2WPC6@28221|Deltaproteobacteria,2MPZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_206144_1	395493.BegalDRAFT_2820	1.73e-87	287.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_198745_1	520709.F985_00531	1.59e-17	79.3	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,1S654@1236|Gammaproteobacteria,3NN9D@468|Moraxellaceae	1236|Gammaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
k59_167800_1	1111730.ATTM01000005_gene51	5.74e-63	207.0	COG3386@1|root,COG3386@2|Bacteria,4NK29@976|Bacteroidetes,1HZAI@117743|Flavobacteriia,2NT7E@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
k59_190835_1	1165841.SULAR_03093	1.63e-95	286.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_28249_1	483219.LILAB_29010	2.07e-75	235.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42YPS@68525|delta/epsilon subdivisions,2WUKF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_144771_1	387093.SUN_0534	2.02e-09	57.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,42X8C@68525|delta/epsilon subdivisions,2YRQE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TIGRFAM nicotinamide mononucleotide transporter PnuC	-	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
k59_144771_2	387093.SUN_0533	4.82e-33	116.0	COG0011@1|root,COG0011@2|Bacteria,1N8R0@1224|Proteobacteria	1224|Proteobacteria	S	YKOF-related Family	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP,Ykof
k59_183075_1	56110.Oscil6304_2504	1.26e-41	142.0	COG2405@1|root,COG2405@2|Bacteria,1G5DX@1117|Cyanobacteria,1HBC1@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
k59_105479_1	767817.Desgi_0931	1.14e-27	112.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia,26769@186807|Peptococcaceae	186801|Clostridia	P	Similarity to COG0471 Di- and tricarboxylate transporters(Evalue	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_105480_1	247634.GPB2148_1144	1.39e-63	209.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,1J9EK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Carboxyl transferase domain	-	-	6.4.1.5	ko:K13778	ko00281,map00281	-	R03494	RC00367,RC00942	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
k59_105480_2	247634.GPB2148_1206	5.81e-21	91.3	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,1RR9Q@1236|Gammaproteobacteria,1J8D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
k59_43777_1	742823.HMPREF9465_00773	7.86e-21	92.8	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,2VJMM@28216|Betaproteobacteria,4PQBE@995019|Sutterellaceae	28216|Betaproteobacteria	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	-	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
k59_43777_2	167550.EV00_1408	6.24e-31	112.0	COG1694@1|root,COG1694@2|Bacteria,1G25W@1117|Cyanobacteria,1MMRE@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	MazG
k59_90033_1	460265.Mnod_7596	8.12e-159	462.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2U4DT@28211|Alphaproteobacteria,1JQUY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_190836_1	1244869.H261_15205	1.07e-18	84.7	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2U4FT@28211|Alphaproteobacteria,2JVMI@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_51410_1	1353529.M899_3012	6.81e-42	158.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2MSRE@213481|Bdellovibrionales,2WIWJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_20251_1	1385935.N836_05515	5.69e-20	85.1	COG0262@1|root,COG0262@2|Bacteria,1G6JU@1117|Cyanobacteria,1HCBU@1150|Oscillatoriales	1117|Cyanobacteria	H	dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
k59_20251_2	1550091.JROE01000002_gene1071	3.38e-23	95.5	2CXV0@1|root,32T2Q@2|Bacteria,4P4J7@976|Bacteroidetes,1IYHP@117747|Sphingobacteriia	976|Bacteroidetes	G	RbsD / FucU transport protein family	-	-	-	-	-	-	-	-	-	-	-	-	RbsD_FucU
k59_136510_1	358681.BBR47_28930	1.42e-19	94.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_190840_1	313596.RB2501_03090	6.57e-49	167.0	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes,1I0SG@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_128962_2	1123318.KB904595_gene1701	5.45e-09	57.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_5220_1	215803.DB30_7545	1.6e-50	181.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria,2YU2Y@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
k59_43786_1	1121405.dsmv_0665	7.49e-46	165.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_213980_1	1347392.CCEZ01000044_gene633	1.24e-68	222.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,36DMV@31979|Clostridiaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k59_229246_1	439235.Dalk_2552	3.58e-43	161.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,42U8I@68525|delta/epsilon subdivisions,2WQCY@28221|Deltaproteobacteria,2MNWM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_121492_2	1190606.AJYG01000007_gene2417	2.5e-17	76.6	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,1XXXX@135623|Vibrionales	135623|Vibrionales	L	methylated DNA-protein cysteine methyltransferase	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
k59_5225_1	929558.SMGD1_0092	6.76e-59	198.0	COG0390@1|root,COG5607@1|root,COG0390@2|Bacteria,COG5607@2|Bacteria,1MV2N@1224|Proteobacteria,42Q0J@68525|delta/epsilon subdivisions,2YPAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transport system, permease component	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k59_12678_1	387093.SUN_0529	6.51e-85	258.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2YMUY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_213982_2	697282.Mettu_2063	6.77e-25	105.0	COG3293@1|root,2ZJP3@2|Bacteria,1R0G2@1224|Proteobacteria,1T4GQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_90051_1	760192.Halhy_3076	2.51e-20	88.6	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes	976|Bacteroidetes	H	Cytosine-specific methyltransferase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_175111_1	313596.RB2501_08955	1.08e-68	222.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1HX8K@117743|Flavobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_160332_1	395493.BegalDRAFT_0275	5.58e-94	280.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,460FZ@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_20984_1	1249627.D779_4223	5.64e-76	237.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales	135613|Chromatiales	K	LysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_28856_1	28072.Nos7524_4000	4.86e-37	128.0	2C3PV@1|root,3307H@2|Bacteria,1GB76@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2834)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2834
k59_28856_2	983545.Glaag_1670	1.19e-40	135.0	COG2944@1|root,COG2944@2|Bacteria,1N0M9@1224|Proteobacteria,1T0CA@1236|Gammaproteobacteria,46D0N@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	MqsA_antitoxin
k59_75391_1	243090.RB3933	3.27e-50	164.0	COG0848@1|root,COG0848@2|Bacteria,2J0CP@203682|Planctomycetes	203682|Planctomycetes	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_67733_1	1165841.SULAR_09074	1.92e-151	436.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_59765_1	395493.BegalDRAFT_1750	4.54e-98	313.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,461RZ@72273|Thiotrichales	72273|Thiotrichales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_121915_1	10224.XP_006815462.1	1.53e-05	52.0	KOG4731@1|root,KOG4731@2759|Eukaryota,39880@33154|Opisthokonta,3BIZD@33208|Metazoa,3CZ8K@33213|Bilateria	33208|Metazoa	D	Electron transfer DM13	-	GO:0000226,GO:0003674,GO:0003824,GO:0004497,GO:0004500,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005700,GO:0006584,GO:0006725,GO:0006807,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0008150,GO:0008152,GO:0009712,GO:0009987,GO:0016043,GO:0016491,GO:0016705,GO:0016715,GO:0018958,GO:0022402,GO:0022607,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044237,GO:0044424,GO:0044464,GO:0051225,GO:0055114,GO:0070925,GO:0071704,GO:0071840,GO:1901360,GO:1901564,GO:1901615	-	-	-	-	-	-	-	-	-	-	DM13,DOMON
k59_5730_1	998674.ATTE01000001_gene3984	3.88e-59	186.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,460Q7@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_137109_1	1168034.FH5T_07770	9.91e-42	139.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,2FT27@200643|Bacteroidia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_137109_2	1168034.FH5T_07775	2.76e-09	57.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
k59_183716_1	2340.JV46_17280	1.02e-69	215.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria,1J5S4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_28866_1	1165841.SULAR_09139	2.45e-115	332.0	2BM55@1|root,32FNN@2|Bacteria,1Q0P6@1224|Proteobacteria,42SB7@68525|delta/epsilon subdivisions,2YPGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA replication regulator	hobA	-	-	-	-	-	-	-	-	-	-	-	HobA
k59_28870_1	1185876.BN8_03026	3.94e-63	218.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y7H@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	-	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_90656_1	1121405.dsmv_2856	2.14e-49	174.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105970_1	498211.CJA_0167	2.67e-65	212.0	COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,1RNBM@1236|Gammaproteobacteria,1FG9D@10|Cellvibrio	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	ybdG	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0016020,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0071944,GO:0104004	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
k59_229845_1	2340.JV46_14380	1.03e-91	276.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1J55A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Arabinose 5-phosphate isomerase	kdsD	GO:0003674,GO:0003824,GO:0016853,GO:0016860,GO:0016861,GO:0019146	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_145410_1	1165841.SULAR_06558	3.67e-126	367.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2YMCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipid a biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_175733_1	1469607.KK073768_gene871	1.78e-12	72.4	COG0399@1|root,COG0500@1|root,COG0399@2|Bacteria,COG0500@2|Bacteria,1GDC5@1117|Cyanobacteria	1117|Cyanobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1,Methyltransf_11
k59_168408_1	228399.appser1_21210	8.67e-89	272.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1Y71Q@135625|Pasteurellales	135625|Pasteurellales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_44333_2	596154.Alide2_1021	1.26e-32	126.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VH34@28216|Betaproteobacteria,4ABJA@80864|Comamonadaceae	28216|Betaproteobacteria	EH	PFAM Thiamine pyrophosphate	ilvX	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
k59_245480_1	457570.Nther_1631	1.96e-85	272.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
k59_160348_1	4533.OB11G23960.1	1.93e-22	98.6	COG2801@1|root,KOG4658@1|root,KOG0017@2759|Eukaryota,KOG4658@2759|Eukaryota,38226@33090|Viridiplantae,3GV16@35493|Streptophyta,3M2YJ@4447|Liliopsida,3IKZD@38820|Poales	35493|Streptophyta	T	disease resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,PAH
k59_222388_1	314275.MADE_1014610	6.42e-59	208.0	COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria	1224|Proteobacteria	NU	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
k59_82861_1	313596.RB2501_13729	1.38e-42	147.0	COG0790@1|root,COG0790@2|Bacteria,4NGW3@976|Bacteroidetes,1HY27@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
k59_82861_2	313596.RB2501_13734	2.65e-17	80.5	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_116437_1	1127673.GLIP_3974	1.92e-69	225.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,465EF@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Na H antiporter	mleN	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_77713_1	314230.DSM3645_23146	4.76e-16	79.0	COG2827@1|root,COG4294@1|root,COG2827@2|Bacteria,COG4294@2|Bacteria,2IY4V@203682|Planctomycetes	203682|Planctomycetes	L	UV-endonuclease UvdE	uvsE	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG,UvdE
k59_201517_1	1537917.JU82_07305	1.71e-51	183.0	COG2202@1|root,COG4191@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,1PFGC@1224|Proteobacteria,42Z6H@68525|delta/epsilon subdivisions,2YRF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,PAS_9
k59_155135_1	2340.JV46_26100	1.62e-73	233.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1J555@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_155135_2	2340.JV46_29220	2.54e-07	51.6	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1J4QH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Permease	perM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
k59_201520_1	1123326.JFBL01000003_gene1848	2.52e-35	123.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2YNWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_201520_2	387093.SUN_2329	2.47e-30	107.0	COG0255@1|root,COG0255@2|Bacteria,1Q5ZI@1224|Proteobacteria,42VCR@68525|delta/epsilon subdivisions,2YQ6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_201520_3	1165841.SULAR_07985	1.81e-27	100.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2YPV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_23545_1	1123236.KB899379_gene1487	2.77e-64	209.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,464CA@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124058_1	762984.HMPREF9445_03238	3.57e-79	259.0	COG1431@1|root,COG1431@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Piwi,SIR2_2
k59_155140_1	378806.STAUR_6538	8.55e-67	219.0	COG0304@1|root,COG0304@2|Bacteria,1Q3B2@1224|Proteobacteria,43927@68525|delta/epsilon subdivisions,2X47V@28221|Deltaproteobacteria,2YYFV@29|Myxococcales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_46775_1	1443111.JASG01000004_gene525	5.68e-42	156.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,3ZW7K@60136|Sulfitobacter	28211|Alphaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_46778_1	1168034.FH5T_11415	2.66e-107	321.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,2FN4X@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_139726_1	1168034.FH5T_21155	6.17e-51	178.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_139726_2	743722.Sph21_3740	5.68e-08	54.7	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_46784_1	319224.Sputcn32_0104	1.07e-19	97.1	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q984@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_405_1	298653.Franean1_3063	1.6e-40	153.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4ERC2@85013|Frankiales	201174|Actinobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_31478_2	1461577.CCMH01000011_gene1772	4.43e-58	195.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1I0PW@117743|Flavobacteriia	976|Bacteroidetes	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_23549_1	477974.Daud_0695	4.81e-27	111.0	COG0840@1|root,COG3039@1|root,COG0840@2|Bacteria,COG3039@2|Bacteria,1TS6Q@1239|Firmicutes,24B6I@186801|Clostridia,260JJ@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_406_1	533240.CRC_03300	7.24e-25	105.0	2DBFF@1|root,2Z8YA@2|Bacteria,1G2KB@1117|Cyanobacteria,1HPNV@1161|Nostocales	1117|Cyanobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_15811_1	1384056.N787_07265	8.04e-48	161.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1X4Q1@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_15811_2	298386.PBPRA3232	1.23e-14	72.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XTQ9@135623|Vibrionales	135623|Vibrionales	O	stringent starvation protein A	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N,GST_N_3
k59_62288_1	234267.Acid_3964	6.54e-06	54.3	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y7IX@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HAMP,Pkinase
k59_193760_1	1168034.FH5T_20930	7.14e-100	308.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_100959_1	1165841.SULAR_03512	8.63e-109	321.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42PQE@68525|delta/epsilon subdivisions,2YNTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_100959_2	1165841.SULAR_03517	4.34e-12	63.9	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,433JY@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_162814_1	29730.Gorai.001G160200.1	4.3e-202	575.0	COG1138@1|root,2QQ5D@2759|Eukaryota,37KAN@33090|Viridiplantae,3G7VB@35493|Streptophyta	35493|Streptophyta	O	cytochrome c	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0017004,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_224736_1	754477.Q7C_1837	8.25e-28	117.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,460GN@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23
k59_78256_2	546414.Deide_15440	1.09e-25	100.0	COG0824@1|root,COG0824@2|Bacteria,1WKEF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
k59_155646_1	1168034.FH5T_13065	2.86e-08	60.1	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia	976|Bacteroidetes	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
k59_62800_1	1192034.CAP_5829	6.94e-26	105.0	COG0278@1|root,COG0316@1|root,COG0607@1|root,COG0278@2|Bacteria,COG0316@2|Bacteria,COG0607@2|Bacteria,1MZ4V@1224|Proteobacteria,43154@68525|delta/epsilon subdivisions,2WWCI@28221|Deltaproteobacteria,2YVCT@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin,Rhodanese
k59_178872_1	4565.Traes_2AL_A313D8886.1	1.13e-110	321.0	29XCM@1|root,2RXRI@2759|Eukaryota,37U8V@33090|Viridiplantae,3GHWM@35493|Streptophyta,3KZGB@4447|Liliopsida,3IHE6@38820|Poales	35493|Streptophyta	S	ATP synthase protein YMF19	atp8	GO:0000276,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005773,GO:0009507,GO:0009536,GO:0016020,GO:0016469,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033177,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045259,GO:0045263,GO:0046872,GO:0046914,GO:0050897,GO:0098796,GO:0098798,GO:0098800	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	DUF1082,YMF19
k59_132362_1	398527.Bphyt_3565	1.46e-32	122.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,1JZUI@119060|Burkholderiaceae	28216|Betaproteobacteria	V	ABC transporter	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_132362_2	472759.Nhal_1310	1.08e-16	78.6	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,1RS93@1236|Gammaproteobacteria,1X0KC@135613|Chromatiales	135613|Chromatiales	I	Squalene phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
k59_16320_1	1550091.JROE01000005_gene2256	1.14e-15	75.5	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1INXZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k59_16320_2	1385515.N791_08305	5.8e-35	138.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X4HY@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_39666_1	2340.JV46_24180	4.02e-61	191.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1J50E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_39666_2	2340.JV46_24170	5.24e-53	178.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1J5A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k59_178901_1	143224.JQMD01000002_gene3521	2.21e-21	98.2	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_78277_2	1165841.SULAR_10039	3.45e-143	408.0	COG2010@1|root,COG2010@2|Bacteria,1PDTK@1224|Proteobacteria,42N5Z@68525|delta/epsilon subdivisions,2YMTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_209735_1	395493.BegalDRAFT_2179	1.61e-102	315.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,45ZPN@72273|Thiotrichales	72273|Thiotrichales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_140297_1	1175654.A0A0S0N897_9CAUD	2.55e-87	278.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae	10699|Siphoviridae	S	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_155660_1	195522.BD01_1491	2.14e-12	74.3	COG0438@1|root,arCOG01411@2157|Archaea,2Y8B0@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_155661_1	1286106.MPL1_12261	6.68e-84	255.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,4609Y@72273|Thiotrichales	72273|Thiotrichales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_155662_1	395493.BegalDRAFT_2372	6.91e-54	182.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,1QWW7@1224|Proteobacteria,1T4BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_70479_2	1121124.JNIX01000015_gene1992	9.2e-18	87.4	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,2KFRU@204458|Caulobacterales	204458|Caulobacterales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_178915_1	313596.RB2501_05865	1.81e-127	378.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NH2P@976|Bacteroidetes,1HXG7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132381_1	1235803.C825_04967	6.35e-120	363.0	COG0436@1|root,COG0436@2|Bacteria,4NHP7@976|Bacteroidetes,2FN3D@200643|Bacteroidia,22XCE@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminotransferase	alaC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_124640_1	596320.NEIFL0001_0622	5.49e-40	145.0	COG1960@1|root,COG1960@2|Bacteria,1NDQ8@1224|Proteobacteria,2WGB5@28216|Betaproteobacteria,2KU3Z@206351|Neisseriales	206351|Neisseriales	I	Acyl-CoA dehydrogenase, N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
k59_31997_1	903818.KI912268_gene2884	3.2e-15	74.7	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	napG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
k59_31997_2	699218.HMPREF0889_0633	2.37e-22	98.6	COG1448@1|root,COG1448@2|Bacteria,1TRJV@1239|Firmicutes,4H2HE@909932|Negativicutes	909932|Negativicutes	E	Aminotransferase, class I	-	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_117041_1	1165841.SULAR_00670	9.36e-32	116.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2YN88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_117041_2	1165841.SULAR_00675	4.29e-57	183.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MUK@68525|delta/epsilon subdivisions,2YNN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ABC transporter superfamily	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00190,M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
k59_16329_1	1165841.SULAR_08719	6.07e-110	327.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42YXJ@68525|delta/epsilon subdivisions,2YR3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
k59_140312_1	1122132.AQYH01000002_gene1283	3.47e-70	230.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,4BAGU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_16332_1	1168034.FH5T_02645	4.16e-119	350.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,2FMUU@200643|Bacteroidia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	wcfX	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_70492_1	557598.LHK_00973	3.69e-57	185.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KQEE@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_209739_1	179408.Osc7112_4792	2.54e-54	200.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3452@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3452@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,Response_reg
k59_217624_1	717773.Thicy_1540	7.08e-44	145.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,460XU@72273|Thiotrichales	72273|Thiotrichales	E	PFAM phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
k59_8683_1	1168034.FH5T_11585	1.79e-31	118.0	COG5383@1|root,COG5383@2|Bacteria,4NGFT@976|Bacteroidetes	976|Bacteroidetes	S	DUF1338	-	-	-	-	-	-	-	-	-	-	-	-	DUF1338
k59_8683_2	99598.Cal7507_0098	1.6e-26	105.0	COG2326@1|root,COG2326@2|Bacteria,1G34U@1117|Cyanobacteria,1HP25@1161|Nostocales	1117|Cyanobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_178916_2	1249627.D779_4108	2.11e-40	138.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1WYD4@135613|Chromatiales	135613|Chromatiales	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_55158_1	1168034.FH5T_06120	1.23e-95	301.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_233119_1	903818.KI912268_gene2066	4.44e-87	272.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
k59_89144_2	2340.JV46_04170	1.56e-38	134.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1J6XQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_27332_2	926556.Echvi_0925	1.58e-16	79.3	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47TYC@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_213004_1	754476.Q7A_2576	8.26e-28	107.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,460NH@72273|Thiotrichales	72273|Thiotrichales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
k59_96947_1	1165841.SULAR_06148	3.01e-40	137.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2YNXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_96947_2	1165841.SULAR_06143	2.84e-60	194.0	COG2404@1|root,COG2404@2|Bacteria,1NHB1@1224|Proteobacteria,42NB0@68525|delta/epsilon subdivisions,2YMQ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
k59_104546_1	1165841.SULAR_01035	4.57e-91	290.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	2|Bacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_19341_1	631362.Thi970DRAFT_03595	3.55e-19	86.3	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales	135613|Chromatiales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
k59_19341_2	395493.BegalDRAFT_0858	2.07e-17	75.1	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,1SH40@1236|Gammaproteobacteria,461GH@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
k59_73753_1	1452718.JBOY01000021_gene715	1.71e-16	79.7	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_4367_1	395493.BegalDRAFT_1288	2.63e-98	288.0	COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1SZTK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Conserved hypothetical ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_1
k59_158859_1	313596.RB2501_06860	1.56e-57	197.0	COG2133@1|root,COG2133@2|Bacteria,4PKAZ@976|Bacteroidetes,1IJ63@117743|Flavobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_158859_2	1120966.AUBU01000003_gene1306	2.36e-10	60.1	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,47MT0@768503|Cytophagia	976|Bacteroidetes	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_112514_1	156889.Mmc1_1816	2.89e-25	103.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,2U11A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k59_11904_2	9940.ENSOARP00000001970	7.32e-10	59.7	COG0457@1|root,KOG1840@2759|Eukaryota,38CFM@33154|Opisthokonta,3BC82@33208|Metazoa,3CWNT@33213|Bilateria,483PC@7711|Chordata,48V59@7742|Vertebrata,3J868@40674|Mammalia,4IZSC@91561|Cetartiodactyla	33208|Metazoa	Z	Kinesin light chain 1	KLC1	GO:0000003,GO:0000226,GO:0000280,GO:0000902,GO:0000904,GO:0000910,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005829,GO:0005856,GO:0005871,GO:0005875,GO:0005929,GO:0006810,GO:0006886,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007097,GO:0007143,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007399,GO:0007409,GO:0008088,GO:0008092,GO:0008104,GO:0008150,GO:0009653,GO:0009791,GO:0009888,GO:0009987,GO:0010927,GO:0010970,GO:0012505,GO:0015031,GO:0015630,GO:0015631,GO:0015833,GO:0016020,GO:0016043,GO:0016049,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016938,GO:0017111,GO:0019894,GO:0019953,GO:0022008,GO:0022402,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0030030,GO:0030154,GO:0030182,GO:0030424,GO:0030426,GO:0030427,GO:0030473,GO:0030703,GO:0030705,GO:0030707,GO:0030855,GO:0031175,GO:0031410,GO:0031967,GO:0031975,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0032984,GO:0032988,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033206,GO:0033267,GO:0034613,GO:0035253,GO:0035418,GO:0035617,GO:0036477,GO:0040007,GO:0040011,GO:0040038,GO:0042886,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045184,GO:0046843,GO:0046907,GO:0048285,GO:0048468,GO:0048477,GO:0048489,GO:0048588,GO:0048589,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048675,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0051179,GO:0051234,GO:0051293,GO:0051295,GO:0051301,GO:0051321,GO:0051640,GO:0051641,GO:0051647,GO:0051648,GO:0051649,GO:0051650,GO:0051653,GO:0051656,GO:0051704,GO:0060429,GO:0060560,GO:0061564,GO:0061640,GO:0070727,GO:0071702,GO:0071705,GO:0071826,GO:0071840,GO:0072384,GO:0097458,GO:0097479,GO:0097480,GO:0097708,GO:0099003,GO:0099111,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140013,GO:0150034,GO:1903008,GO:1903046,GO:1990138	-	ko:K10407	ko05132,map05132	-	-	-	ko00000,ko00001,ko03019,ko04812	-	-	-	DUF2315,TPR_10,TPR_12,TPR_7,TPR_8
k59_104557_1	395493.BegalDRAFT_0278	1.84e-174	501.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_11913_1	452637.Oter_0108	1.16e-56	189.0	COG2382@1|root,COG2382@2|Bacteria,46UMK@74201|Verrucomicrobia,3K8H2@414999|Opitutae	2|Bacteria	P	Belongs to the glycosyl hydrolase 13 family	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Barstar,CBM_48,Esterase
k59_120295_1	156889.Mmc1_3637	1.83e-104	322.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,2UCZG@28211|Alphaproteobacteria	1224|Proteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_143574_1	401053.AciPR4_1875	2.24e-53	183.0	COG0621@1|root,COG0621@2|Bacteria,3Y2GT@57723|Acidobacteria,2JIEP@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_158872_1	2340.JV46_23640	1.51e-174	530.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_42821_1	637389.Acaty_c2233	1.23e-42	144.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,2NBS8@225057|Acidithiobacillales	225057|Acidithiobacillales	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
k59_35664_2	1117318.PRUB_22856	9.98e-18	77.8	2BI4W@1|root,32AFP@2|Bacteria,1RKZI@1224|Proteobacteria,1S6WU@1236|Gammaproteobacteria,2Q4TM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k59_35664_3	342113.DM82_3470	7.3e-11	60.1	2CU57@1|root,32SUP@2|Bacteria,1N68C@1224|Proteobacteria,2WFCX@28216|Betaproteobacteria,1KDVX@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_244309_1	1123399.AQVE01000026_gene3014	3.32e-21	94.4	COG0834@1|root,COG2010@1|root,COG0834@2|Bacteria,COG2010@2|Bacteria,1MWWZ@1224|Proteobacteria,1S2ZV@1236|Gammaproteobacteria,462HI@72273|Thiotrichales	72273|Thiotrichales	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k59_244309_2	1190606.AJYG01000051_gene1292	3.02e-09	57.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1Y0DT@135623|Vibrionales	135623|Vibrionales	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
k59_228771_1	326297.Sama_2272	8.17e-33	118.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,2QAKC@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM CheW domain protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_58603_1	2340.JV46_05320	6.48e-50	173.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,1S0H0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_58603_2	84531.JMTZ01000022_gene4160	3.91e-05	49.3	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X787@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	cycM	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_89545_1	395493.BegalDRAFT_3090	4.82e-73	229.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,460ZA@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_81910_2	1165841.SULAR_00620	1.87e-35	134.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,42MQU@68525|delta/epsilon subdivisions,2YMC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_50847_1	1168034.FH5T_11715	1.93e-27	108.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FP4D@200643|Bacteroidia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_50847_2	1392486.JIAF01000004_gene1357	2.27e-15	77.8	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,2FKYE@200643|Bacteroidia	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
k59_12245_1	870187.Thini_4228	2.4e-66	222.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,461MH@72273|Thiotrichales	72273|Thiotrichales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_128516_1	313603.FB2170_06550	3.53e-34	124.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,1HXD6@117743|Flavobacteriia,2PG3H@252356|Maribacter	976|Bacteroidetes	L	RNase H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
k59_128516_2	411479.BACUNI_00991	2.89e-25	99.8	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,2FPNN@200643|Bacteroidia,4ANFT@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_167209_1	1168034.FH5T_10815	3.23e-122	357.0	COG0204@1|root,COG0204@2|Bacteria,4NGR9@976|Bacteroidetes,2FM79@200643|Bacteroidia	976|Bacteroidetes	I	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_50854_1	985054.JQEZ01000001_gene2869	1.09e-21	94.7	COG2114@1|root,COG4753@1|root,COG2114@2|Bacteria,COG4753@2|Bacteria,1PYP4@1224|Proteobacteria,2TVEP@28211|Alphaproteobacteria,4NCYJ@97050|Ruegeria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
k59_159265_1	1280001.BAOA01000138_gene1985	6.54e-47	170.0	COG3659@1|root,COG3659@2|Bacteria,1R8TI@1224|Proteobacteria,1S21B@1236|Gammaproteobacteria,1XVR4@135623|Vibrionales	135623|Vibrionales	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
k59_89553_1	298386.PBPRA1243	4.79e-10	62.0	COG3187@1|root,COG3895@1|root,COG4461@1|root,COG3187@2|Bacteria,COG3895@2|Bacteria,COG4461@2|Bacteria,1PF0Q@1224|Proteobacteria,1TBDV@1236|Gammaproteobacteria,1XWBZ@135623|Vibrionales	135623|Vibrionales	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
k59_89553_2	314285.KT71_06252	1.32e-21	95.1	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S876@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_228779_1	1250278.JQNQ01000001_gene1687	3.22e-17	87.4	COG2911@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,SprB
k59_19786_1	1168034.FH5T_02495	8.08e-41	148.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
k59_97435_2	395493.BegalDRAFT_1181	1.75e-152	436.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,4606E@72273|Thiotrichales	72273|Thiotrichales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
k59_74189_1	240016.ABIZ01000001_gene99	1.1e-42	155.0	COG2939@1|root,COG2939@2|Bacteria,46UB7@74201|Verrucomicrobia,2IVCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_136050_1	991905.SL003B_1504	5.38e-31	119.0	COG2223@1|root,COG2223@2|Bacteria,1MW71@1224|Proteobacteria,2TWVJ@28211|Alphaproteobacteria,4BP5M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_221296_1	665956.HMPREF1032_00553	1.13e-35	130.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,3WGTY@541000|Ruminococcaceae	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_221296_2	234267.Acid_5232	1.96e-07	55.5	COG1972@1|root,COG1972@2|Bacteria,3Y2KI@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_244332_1	1385515.N791_09155	3.64e-67	220.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1X3UC@135614|Xanthomonadales	135614|Xanthomonadales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_236746_1	1168034.FH5T_08955	2.35e-48	159.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,2FPCJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_182626_1	3988.XP_002535312.1	7.69e-133	396.0	COG0197@1|root,KOG3422@2759|Eukaryota,38965@33090|Viridiplantae,3GY34@35493|Streptophyta,4JV2J@91835|fabids	35493|Streptophyta	J	RIBOSOMAL protein	-	-	-	ko:K02878,ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16,Ribosomal_S3_C
k59_228792_1	1114959.SZMC14600_21391	6.73e-62	202.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4DYEK@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_221304_1	1396141.BATP01000003_gene5164	8.28e-62	205.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia,2IV14@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_143980_1	1286631.X805_37510	1.68e-53	182.0	COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,2VMRJ@28216|Betaproteobacteria,1KKIA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
k59_213450_1	29760.VIT_09s0054g00520.t01	6.4e-140	424.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	ycf1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	-	-	-	-	-	-	-	-	-	Ycf1
k59_136066_1	313603.FB2170_06830	4.68e-18	79.7	COG2340@1|root,COG2340@2|Bacteria,4NNKS@976|Bacteroidetes,1I1XU@117743|Flavobacteriia,2PHFF@252356|Maribacter	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
k59_136066_2	313596.RB2501_07695	4.04e-55	175.0	COG1917@1|root,COG1917@2|Bacteria,4PKJ0@976|Bacteroidetes,1IJAI@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
k59_89557_1	1168065.DOK_09881	3.15e-105	310.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1J56X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_213458_1	1541065.JRFE01000073_gene3320	7.35e-56	188.0	COG3464@1|root,COG3464@2|Bacteria,1G42D@1117|Cyanobacteria,3VMW4@52604|Pleurocapsales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_43283_1	1047013.AQSP01000142_gene222	3.65e-15	83.2	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_128546_2	2340.JV46_13550	1.67e-38	130.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1J6YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
k59_43289_1	717772.THIAE_03645	1.48e-58	204.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_167256_1	1206558.I7K2T5_9CAUD	7.22e-06	54.3	4QBG4@10239|Viruses,4QUZA@35237|dsDNA viruses  no RNA stage,4QRSK@28883|Caudovirales,4QJW4@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136072_1	1469245.JFBG01000052_gene2154	6.68e-13	67.4	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1WWRX@135613|Chromatiales	135613|Chromatiales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_136072_2	1123366.TH3_14994	4.85e-37	139.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2U0EN@28211|Alphaproteobacteria,2JPP3@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_228808_1	4565.Traes_2AL_4FD0AE093.1	6.18e-162	455.0	28P22@1|root,2QVNI@2759|Eukaryota,37SGH@33090|Viridiplantae,3GFX8@35493|Streptophyta,3M2WZ@4447|Liliopsida,3I54V@38820|Poales	35493|Streptophyta	S	30S ribosomal protein S4, chloroplastic	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
k59_151401_2	880071.Fleli_3454	4.56e-63	218.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,47KK6@768503|Cytophagia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_143995_1	886377.Murru_2082	3.22e-44	154.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_143995_2	313596.RB2501_02485	6.46e-38	136.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1I0Z6@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_198211_1	1165841.SULAR_01445	1.33e-120	357.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DEAD DEAH box helicase	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_201316_1	590409.Dd586_2073	5.21e-15	75.1	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,2JDTZ@204037|Dickeya	1236|Gammaproteobacteria	S	Haloacid dehalogenase domain protein hydrolase type 3	yedP	-	2.7.1.31,3.1.3.70	ko:K07026,ko:K15918	ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200	M00532	R01514,R05790	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3,S6PP
k59_147126_1	1536773.R70331_03260	2.63e-34	137.0	COG5002@1|root,COG5002@2|Bacteria,1UJ5U@1239|Firmicutes,4HG8M@91061|Bacilli,26S07@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA
k59_100723_1	470145.BACCOP_02166	3.3e-24	97.4	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,4AKU6@815|Bacteroidaceae	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_131709_1	1123489.AUAN01000005_gene1633	3.29e-08	57.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4H21I@909932|Negativicutes	909932|Negativicutes	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_131709_2	1168034.FH5T_11910	5.19e-97	291.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,2FMND@200643|Bacteroidia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_69795_1	1121459.AQXE01000006_gene81	1.62e-70	226.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42N2K@68525|delta/epsilon subdivisions,2WJ5D@28221|Deltaproteobacteria,2M8TA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	DAO,FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
k59_170410_1	512565.AMIS_1810	3.33e-51	184.0	COG0745@1|root,COG1511@1|root,COG2770@1|root,COG4251@1|root,COG0745@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG4251@2|Bacteria,2GKQX@201174|Actinobacteria,4D9S8@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_209058_1	545243.BAEV01000007_gene1388	3.05e-18	83.6	COG0437@1|root,COG0437@2|Bacteria,1USMM@1239|Firmicutes,24G7X@186801|Clostridia,36KDI@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_4,Fer4_7
k59_7911_1	1165841.SULAR_07585	2.74e-142	424.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_170411_1	1121930.AQXG01000002_gene1931	7.38e-100	301.0	COG0701@1|root,COG0701@2|Bacteria,4NI2E@976|Bacteroidetes	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_54362_1	1089545.KB913037_gene7359	2.02e-09	61.6	COG2706@1|root,COG2706@2|Bacteria,2I6SW@201174|Actinobacteria	201174|Actinobacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
k59_31622_1	251221.35212497	3.86e-29	119.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,1GC0D@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_170787_1	1123228.AUIH01000092_gene552	1.7e-72	236.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162990_1	870187.Thini_1858	2.56e-84	275.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0753 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2309
k59_232742_1	1397528.Q671_16990	1.06e-74	231.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,1RY10@1236|Gammaproteobacteria,1XNMD@135619|Oceanospirillales	135619|Oceanospirillales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_33
k59_108852_1	385682.AFSL01000035_gene2906	5.1e-32	125.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae	976|Bacteroidetes	O	Trypsin	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
k59_108852_2	1168034.FH5T_20500	1.16e-08	54.3	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,2FNYZ@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_147517_1	243231.GSU0716	1.64e-45	157.0	COG4249@1|root,COG4249@2|Bacteria,1R45G@1224|Proteobacteria	1224|Proteobacteria	S	PFAM peptidase C14, caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Peptidase_C14,Peptidase_M15_3
k59_23719_1	2340.JV46_03400	7.49e-59	186.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1J4HC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_15991_1	1123392.AQWL01000009_gene1082	2.85e-62	193.0	COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria,2W0BB@28216|Betaproteobacteria,1KSHR@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4
k59_15991_2	765912.Thimo_1219	1.76e-56	191.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_170793_1	1232683.ADIMK_1046	8.4e-14	71.2	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,467AA@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG4968 Tfp pilus assembly protein PilE	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
k59_163006_1	1168034.FH5T_14460	2.3e-28	112.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
k59_163006_2	509635.N824_21705	1.59e-08	54.7	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,1ISCN@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_147529_1	686578.AFFX01000005_gene4334	5.62e-55	183.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_147529_2	716928.AJQT01000011_gene5052	2.28e-21	89.4	COG4665@1|root,COG4665@2|Bacteria,1RDYM@1224|Proteobacteria,2TVMY@28211|Alphaproteobacteria,4BEUU@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_39281_1	595460.RRSWK_00180	1.94e-131	387.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Fucosidase_C
k59_178579_1	69328.PVLB_26362	5.33e-11	70.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,NIT,TarH
k59_224919_2	649764.HMPREF0762_01871	1e-19	88.2	COG2314@1|root,COG2314@2|Bacteria,2HVAB@201174|Actinobacteria,4CWJH@84998|Coriobacteriia	84998|Coriobacteriia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
k59_101145_1	1198452.Jab_2c06630	0.000385	45.1	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2WBNE@28216|Betaproteobacteria,4765K@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_101145_2	309807.SRU_2845	3.86e-06	51.2	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1FIS9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3 domain protein	-	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_85706_1	550540.Fbal_3477	4.32e-12	70.9	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	type II and III secretion system protein	mshL	-	-	ko:K12282	-	-	-	-	ko00000,ko02044	-	-	-	STN,Secretin,Secretin_N_2
k59_31636_1	1589733.A0A0C5AAX2_9CAUD	2.19e-21	100.0	4QEE7@10239|Viruses,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201711_1	749222.Nitsa_0866	1.82e-37	140.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_8337_1	313596.RB2501_03340	2.88e-103	312.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1IJBB@117743|Flavobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_132068_1	483219.LILAB_21700	6.07e-19	90.9	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
k59_54795_1	945713.IALB_3192	7.96e-80	266.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13,2.1.1.245,2.1.1.258	ko:K00197,ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00357,M00377,M00422	R00946,R02289,R09096,R09365,R10219,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_15998_1	270374.MELB17_22535	6.59e-137	403.0	COG4467@1|root,COG4467@2|Bacteria,1QW8C@1224|Proteobacteria,1S2JX@1236|Gammaproteobacteria,46BUT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_224923_1	1168034.FH5T_07320	7.85e-40	146.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,2FN8J@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase family M3	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_224923_2	1168034.FH5T_07325	9.91e-87	258.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,2FMUN@200643|Bacteroidia	976|Bacteroidetes	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_108868_1	1178540.BA70_06940	8.02e-55	194.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_93516_1	1165841.SULAR_07595	3.39e-121	352.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_31642_1	387093.SUN_2396	3.01e-58	181.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2YPWS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
k59_23747_1	247633.GP2143_03014	5.41e-76	242.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1JBW8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_170816_1	1161401.ASJA01000020_gene572	2.5e-18	79.3	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,43Y02@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_170816_2	1123518.ARWI01000001_gene571	4.55e-38	143.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,45ZVJ@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_147534_1	38654.XP_006016886.1	6.25e-13	72.8	COG1960@1|root,KOG0137@2759|Eukaryota,38HSX@33154|Opisthokonta,3BG8S@33208|Metazoa,3D29E@33213|Bilateria,4816U@7711|Chordata,48Y8M@7742|Vertebrata	33208|Metazoa	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
k59_124279_1	318464.IO99_12275	1.36e-22	101.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,36DJB@31979|Clostridiaceae	186801|Clostridia	C	iron hydrogenase, small subunit	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS07205	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3
k59_224932_1	1123514.KB905899_gene981	2.37e-72	223.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,460TE@72273|Thiotrichales	72273|Thiotrichales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k59_16011_1	396588.Tgr7_2694	6.92e-34	130.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_23751_1	879212.DespoDRAFT_00665	4.7e-51	173.0	COG3385@1|root,COG3385@2|Bacteria,1REZ3@1224|Proteobacteria,42RPA@68525|delta/epsilon subdivisions,2WNFF@28221|Deltaproteobacteria,2MPI9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_8346_1	762376.AXYL_04318	8.28e-46	163.0	28KBW@1|root,2Z9YU@2|Bacteria,1R668@1224|Proteobacteria,2VIT0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2955)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2955
k59_139951_1	641526.ADIWIN_3252	5.22e-51	181.0	COG2211@1|root,COG5309@1|root,COG2211@2|Bacteria,COG5309@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia	976|Bacteroidetes	G	COG2211 Na melibiose symporter and related	uidB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
k59_186277_1	796606.BMMGA3_03470	8.76e-28	117.0	COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus	91061|Bacilli	N	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_240359_2	1270196.JCKI01000008_gene1365	1.24e-28	104.0	2BI4W@1|root,330YN@2|Bacteria,4P48H@976|Bacteroidetes	976|Bacteroidetes	S	Antirepresssor protein RebB	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k59_217309_1	314275.MADE_1014600	4.06e-65	213.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
k59_201727_1	927677.ALVU02000001_gene3063	1.01e-28	117.0	COG3240@1|root,COG3240@2|Bacteria,1FZV1@1117|Cyanobacteria	1117|Cyanobacteria	I	Phospholipase lecithinase hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
k59_139953_1	944547.ABLL_0193	6.39e-120	347.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42T87@68525|delta/epsilon subdivisions,2YMZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_47029_1	1042377.AFPJ01000051_gene87	5.84e-60	199.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,46DHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_47029_2	1298867.AUES01000059_gene4749	8.67e-09	56.2	COG4313@1|root,COG4313@2|Bacteria,1PXJ3@1224|Proteobacteria,2UAPJ@28211|Alphaproteobacteria,3K39K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_116676_1	1168034.FH5T_10945	5.1e-109	333.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,2FM68@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_198498_1	1249627.D779_4054	4.86e-102	312.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alkaline phosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_190648_1	1165841.SULAR_00350	2.31e-91	277.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2YMEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_20078_2	2340.JV46_17520	2.02e-115	338.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,1J8D6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	ThiI,tRNA_Me_trans
k59_144458_1	1168034.FH5T_11905	2.57e-67	218.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,2FM93@200643|Bacteroidia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_144458_2	1168034.FH5T_11900	1.42e-29	115.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,2FP0X@200643|Bacteroidia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_183379_1	1168034.FH5T_08780	1.17e-78	244.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,2FPCQ@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_12952_1	998674.ATTE01000001_gene274	6.62e-25	101.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,1S185@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0685 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_12952_2	366394.Smed_1782	3.16e-41	141.0	COG0685@1|root,COG0685@2|Bacteria,1RHDY@1224|Proteobacteria,2U4I0@28211|Alphaproteobacteria,4B784@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_237494_1	290315.Clim_0789	1.06e-19	86.3	28IYQ@1|root,2Z8WB@2|Bacteria	2|Bacteria	S	Type II restriction endonuclease EcoO109I	-	-	-	-	-	-	-	-	-	-	-	-	RE_EcoO109I
k59_237494_2	290317.Cpha266_1517	9.47e-26	102.0	28IYQ@1|root,2Z8WB@2|Bacteria	2|Bacteria	S	Type II restriction endonuclease EcoO109I	-	-	-	-	-	-	-	-	-	-	-	-	RE_EcoO109I
k59_229489_1	710243.XP_007602032.1	0.000616	43.1	COG4297@1|root,2R1TU@2759|Eukaryota,39TIY@33154|Opisthokonta,3NXS1@4751|Fungi,3QKX9@4890|Ascomycota,2195J@147550|Sordariomycetes,1F1Y3@1028384|Glomerellales	4751|Fungi	S	Flavin-containing superfamily Amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
k59_229489_2	639283.Snov_2622	1.53e-24	100.0	COG0031@1|root,COG0031@2|Bacteria,1MUR6@1224|Proteobacteria,2TRHT@28211|Alphaproteobacteria,3EZ2E@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_82556_1	522373.Smlt4562	6.78e-05	46.2	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,1X5EV@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_20562_1	118168.MC7420_4451	7.83e-62	216.0	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG3850@1|root,COG4191@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHXQ@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_175351_1	349521.HCH_00067	1.18e-50	174.0	COG0330@1|root,COG0330@2|Bacteria,1R93I@1224|Proteobacteria,1RPTI@1236|Gammaproteobacteria,1XINU@135619|Oceanospirillales	135619|Oceanospirillales	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_113581_1	2340.JV46_06570	5.23e-110	340.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_75041_1	395493.BegalDRAFT_0413	4.97e-213	613.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,45ZTI@72273|Thiotrichales	72273|Thiotrichales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_44041_1	765910.MARPU_08130	1.17e-16	73.9	2E7X9@1|root,332BU@2|Bacteria,1N7MD@1224|Proteobacteria,1SDFK@1236|Gammaproteobacteria,1WZ93@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44041_2	7213.XP_004528652.1	1.11e-18	84.3	COG0289@1|root,2S0IY@2759|Eukaryota,3AEPI@33154|Opisthokonta,3BYU3@33208|Metazoa,3DERJ@33213|Bilateria,4224G@6656|Arthropoda,3SP5D@50557|Insecta	33208|Metazoa	E	Dihydrodipicolinate reductase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DapB_C,DapB_N
k59_145056_1	485914.Hmuk_2921	1.27e-09	65.1	COG3979@1|root,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PKD
k59_214235_1	1165841.SULAR_06468	1.24e-122	359.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2YMKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_12968_2	977880.RALTA_B0768	2.86e-31	122.0	COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2VNZS@28216|Betaproteobacteria,1K0M2@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_136751_1	243265.plu2670	2.18e-39	152.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_206339_2	1397284.AYMN01000002_gene2281	8.13e-07	50.1	2DN5T@1|root,32VQG@2|Bacteria,1N6A1@1224|Proteobacteria,1SB7Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160048_1	395493.BegalDRAFT_0928	1.2e-89	278.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZTS@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_51678_1	387093.SUN_1164	1.38e-74	249.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_136757_1	391598.FBBAL38_10672	7.44e-70	231.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_206349_1	1168034.FH5T_10370	2.62e-24	100.0	2EUVH@1|root,33NAZ@2|Bacteria,4NXNT@976|Bacteroidetes,2FZE7@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_121646_1	1408321.JNJD01000006_gene1264	3.32e-10	62.4	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27QTS@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,Hpt,MASE3,Response_reg
k59_113599_1	95619.PM1_0229060	2.97e-30	109.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_113599_2	1472716.KBK24_0127865	9.66e-07	53.9	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1K3JW@119060|Burkholderiaceae	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_82564_1	1235802.C823_00633	1.84e-07	51.6	COG3041@1|root,COG3041@2|Bacteria,1VCQT@1239|Firmicutes,25D4U@186801|Clostridia	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
k59_82564_2	102232.GLO73106DRAFT_00036060	5.37e-07	50.4	COG0639@1|root,COG0639@2|Bacteria,1GEP2@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
k59_51690_1	1192034.CAP_7468	2.84e-20	95.5	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_75043_2	2340.JV46_22190	3.18e-33	117.0	COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1J6Y6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	YcgL domain-containing protein	ycgL	-	-	ko:K09902	-	-	-	-	ko00000	-	-	-	YcgL
k59_183395_1	929558.SMGD1_2862	1.06e-70	234.0	COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_183397_1	1122599.AUGR01000001_gene392	1.36e-36	135.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1XHX0@135619|Oceanospirillales	135619|Oceanospirillales	C	lysine 2,3-aminomutase	epmB	-	-	ko:K19810	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_105644_1	391615.ABSJ01000037_gene932	3.32e-43	142.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
k59_105644_2	715451.ambt_21960	8.79e-61	187.0	COG4680@1|root,COG4680@2|Bacteria,1N036@1224|Proteobacteria,1S6VU@1236|Gammaproteobacteria,46831@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
k59_183407_1	1165841.SULAR_10584	5.16e-102	297.0	COG0790@1|root,COG0790@2|Bacteria,1NPMK@1224|Proteobacteria,42XBW@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF1566
k59_82567_1	1029823.AFIE01000001_gene2103	2.68e-130	384.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,3NJ0S@468|Moraxellaceae	1236|Gammaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_237520_1	1120965.AUBV01000004_gene1037	3.57e-78	261.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_121655_1	1288826.MSNKSG1_03510	3.44e-41	142.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_229509_1	1046724.KB889882_gene1831	3.15e-79	241.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,465C4@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG4149 ABC-type molybdate transport system, permease component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_82570_1	1123518.ARWI01000001_gene236	4.66e-31	121.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,45ZN9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_82570_2	387093.SUN_0195	1.97e-44	155.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,430CZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_113611_1	999419.HMPREF1077_00781	2.48e-31	126.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia,22W01@171551|Porphyromonadaceae	976|Bacteroidetes	GKT	Pyruvate phosphate dikinase, PEP pyruvate binding domain	ppsA	-	-	-	-	-	-	-	-	-	-	-	PPDK_N,Response_reg
k59_245129_1	1168034.FH5T_10840	3.04e-33	119.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,2FM8T@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
k59_245129_2	1123234.AUKI01000018_gene296	7.95e-34	127.0	COG0563@1|root,COG0634@1|root,COG0563@2|Bacteria,COG0634@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
k59_75060_1	215803.DB30_5190	1.42e-38	143.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,437GH@68525|delta/epsilon subdivisions,2X2P4@28221|Deltaproteobacteria,2YU9N@29|Myxococcales	28221|Deltaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_222030_1	765913.ThidrDRAFT_2043	1.35e-74	241.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_75071_1	313596.RB2501_14964	1.74e-89	276.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_5471_1	306281.AJLK01000042_gene5266	1.24e-36	144.0	COG0784@1|root,COG3437@1|root,COG5000@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG5000@2|Bacteria,1GHJE@1117|Cyanobacteria,1JI33@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_36555_1	1123401.JHYQ01000022_gene1090	2.39e-88	271.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,461WN@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_214256_1	2340.JV46_06270	1.21e-105	315.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1J4VY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0568 DNA-directed RNA polymerase, sigma subunit	rpoS	GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_51718_1	1249997.JHZW01000001_gene4160	7.95e-64	202.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia,2PH3R@252356|Maribacter	976|Bacteroidetes	I	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_51718_2	313596.RB2501_12362	5.7e-27	106.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1HWXZ@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_28572_1	1282876.BAOK01000002_gene450	6.98e-16	77.4	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,4BPP4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_67422_1	3880.AES61811	7.49e-08	53.9	2E724@1|root,2SDQ0@2759|Eukaryota,37XK8@33090|Viridiplantae,3GMV1@35493|Streptophyta	3880.AES61811|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67422_2	3880.AES58569	4.35e-12	65.1	2E724@1|root,2SDQ0@2759|Eukaryota,37XK8@33090|Viridiplantae,3GMV1@35493|Streptophyta	3880.AES58569|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67422_3	3847.GLYMA0973S200.1	1.26e-27	103.0	2EZXM@1|root,2T167@2759|Eukaryota,3823B@33090|Viridiplantae,3GS09@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67422_4	4577.GRMZM5G870438_P01	2.93e-20	84.7	2F0VK@1|root,2T1YX@2759|Eukaryota,382TZ@33090|Viridiplantae,3GS2P@35493|Streptophyta,3M9UW@4447|Liliopsida,3IQFD@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67422_5	3649.evm.model.supercontig_155.2	1.11e-07	49.7	2F0VK@1|root,2T1YX@2759|Eukaryota,382TZ@33090|Viridiplantae,3GS2P@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214259_1	1049564.TevJSym_as00140	2.16e-170	484.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1J53B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Aminotransferase	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUMNK88_1353.UMNK88_158	Aminotran_3
k59_63096_2	2340.JV46_05620	8.29e-61	189.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S7F0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_148136_1	1168034.FH5T_04030	9.12e-104	308.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,2FPE1@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_55392_2	234267.Acid_1957	6.78e-14	73.6	COG0457@1|root,COG0760@1|root,COG0457@2|Bacteria,COG0760@2|Bacteria,3Y67U@57723|Acidobacteria	57723|Acidobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_148140_1	1121396.KB893068_gene1476	5.09e-12	62.0	COG4802@1|root,COG4802@2|Bacteria,1RI70@1224|Proteobacteria,42SXJ@68525|delta/epsilon subdivisions,2WP19@28221|Deltaproteobacteria,2MKJ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
k59_148140_2	1121405.dsmv_3379	2.54e-46	150.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
k59_70754_1	572477.Alvin_1488	8.09e-18	93.2	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_55393_1	177437.HRM2_46500	2.36e-37	139.0	COG0457@1|root,COG1944@1|root,COG0457@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42N4B@68525|delta/epsilon subdivisions,2WJ34@28221|Deltaproteobacteria,2MHRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,YcaO
k59_124994_1	631362.Thi970DRAFT_03628	5.58e-33	127.0	COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,1RQAX@1236|Gammaproteobacteria,1WWP5@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1232_1	1165841.SULAR_02753	1.34e-22	94.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YN8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0191	Fer2_3,Fer4_8
k59_1232_2	1165841.SULAR_02758	4.8e-104	306.0	COG2048@1|root,COG2048@2|Bacteria,1RFWK@1224|Proteobacteria,43B86@68525|delta/epsilon subdivisions,2YT6P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Heterodisulfide reductase subunit B	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
k59_94156_1	1217718.ALOU01000112_gene4316	1.27e-37	136.0	COG1075@1|root,COG1075@2|Bacteria,1NSK3@1224|Proteobacteria,2WG1G@28216|Betaproteobacteria,1KI8H@119060|Burkholderiaceae	28216|Betaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94156_2	740709.A10D4_09904	8.91e-24	99.4	COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,1RS2M@1236|Gammaproteobacteria,2QEWV@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	AbgT putative transporter family	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
k59_32426_2	1121943.KB899990_gene3768	4.16e-48	164.0	COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,1SYVW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k59_86339_1	1168034.FH5T_05205	2.2e-60	191.0	COG3439@1|root,COG3439@2|Bacteria,4PB0E@976|Bacteroidetes,2FY5F@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_140525_1	179408.Osc7112_1054	6.46e-68	219.0	COG3335@1|root,COG3335@2|Bacteria,1GQVS@1117|Cyanobacteria,1HC3Z@1150|Oscillatoriales	2|Bacteria	L	Rhodopirellula transposase family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_16623_1	1242864.D187_001007	2.06e-12	72.4	2DB8Y@1|root,2Z7TF@2|Bacteria,1NCMY@1224|Proteobacteria,43B9S@68525|delta/epsilon subdivisions,2X6NX@28221|Deltaproteobacteria,2Z3BY@29|Myxococcales	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
k59_40016_1	1460634.JCM19037_4055	2.67e-08	59.7	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HDUW@91061|Bacilli	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18349	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_55414_1	983545.Glaag_0584	1.32e-26	114.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
k59_40021_1	1149133.ppKF707_3943	9.41e-66	213.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1YEND@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	OU	Peptidase family S49 N-terminal	sohB	GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0019538,GO:0043170,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901564	-	ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49,Peptidase_S49_N
k59_125009_1	525897.Dbac_1048	4.22e-31	123.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2M7Y6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
k59_24364_1	1121875.KB907553_gene18	2.45e-13	72.4	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,1HZYC@117743|Flavobacteriia	976|Bacteroidetes	M	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_240949_1	1216976.AX27061_3626	5.58e-89	273.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,3T1US@506|Alcaligenaceae	28216|Betaproteobacteria	M	Cyclopropane fatty acid synthase and related methyltransferases	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_47697_1	1177179.A11A3_07935	3.86e-119	349.0	COG3950@1|root,COG3950@2|Bacteria,1MUE0@1224|Proteobacteria,1RZ7D@1236|Gammaproteobacteria,1XMHI@135619|Oceanospirillales	135619|Oceanospirillales	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
k59_210036_1	1121405.dsmv_1445	4.01e-77	247.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MI6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_101815_1	765912.Thimo_3542	4.05e-76	239.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,1WYA3@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_163689_2	1049564.TevJSym_ac00030	6.37e-107	314.0	COG2863@1|root,COG2863@2|Bacteria,1RBXV@1224|Proteobacteria,1SEAS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_32437_1	330214.NIDE3635	6.44e-104	320.0	COG4108@1|root,COG4108@2|Bacteria,3J0WP@40117|Nitrospirae	40117|Nitrospirae	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
k59_55427_2	589865.DaAHT2_2431	2.18e-104	322.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MPFP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_109538_1	1163409.UUA_12770	1.06e-35	130.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,1X3E7@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78612_2	589865.DaAHT2_0671	1.93e-17	77.0	COG2197@1|root,COG2197@2|Bacteria,1N4GT@1224|Proteobacteria,42TY6@68525|delta/epsilon subdivisions,2WQVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_217928_2	242527.Q6V7M7_9CAUD	1.28e-12	68.2	4QDZP@10239|Viruses,4R039@35237|dsDNA viruses  no RNA stage,4QSG5@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194615_1	388467.A19Y_1634	2.72e-13	71.2	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HAEN@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding
k59_194615_2	1319815.HMPREF0202_02518	2.23e-06	48.5	COG0733@1|root,COG0733@2|Bacteria,378ZP@32066|Fusobacteria	32066|Fusobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_55447_2	1033810.HLPCO_000763	4.37e-05	47.4	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,Peptidase_MA_2
k59_233495_1	1230343.CANP01000005_gene438	1.89e-15	76.6	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,1T34W@1236|Gammaproteobacteria,1JCF4@118969|Legionellales	118969|Legionellales	C	Phosphate acetyl/butaryl transferase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas,PTA_PTB
k59_202411_1	1168034.FH5T_14745	1.11e-143	423.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FMX8@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_78619_1	439235.Dalk_4801	4.52e-76	239.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_186888_2	1027273.GZ77_18120	1.73e-23	92.4	COG2026@1|root,COG2026@2|Bacteria,1QDRS@1224|Proteobacteria,1T80W@1236|Gammaproteobacteria,1XQUV@135619|Oceanospirillales	135619|Oceanospirillales	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_186888_3	395493.BegalDRAFT_3542	6.83e-67	221.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NMT1,PAS,PAS_9,Response_reg
k59_217940_1	73044.JNXP01000002_gene1895	0.000452	43.5	COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG5297@2|Bacteria,2I2VY@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase family 5	celA	-	3.2.1.4	ko:K01179,ko:K20628	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase,fn3
k59_109546_1	2340.JV46_15090	1.11e-116	345.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1J4X6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
k59_217941_1	313628.LNTAR_13282	8.34e-105	315.0	COG2871@1|root,COG2871@2|Bacteria	2|Bacteria	C	sodium ion transport	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_155916_1	1249627.D779_2755	4.56e-90	273.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,1WW82@135613|Chromatiales	135613|Chromatiales	E	PFAM Pyruvate carboxyltransferase	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_163705_1	933262.AXAM01000030_gene794	4.4e-60	203.0	COG1208@1|root,COG4857@1|root,COG1208@2|Bacteria,COG4857@2|Bacteria,1R1X2@1224|Proteobacteria,43DC4@68525|delta/epsilon subdivisions,2WVQJ@28221|Deltaproteobacteria,2MPP2@213118|Desulfobacterales	28221|Deltaproteobacteria	JM	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,NTP_transferase
k59_217942_1	701176.VIBRN418_18413	5.72e-43	149.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,1S9F3@1236|Gammaproteobacteria,1XSID@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_132755_1	1267535.KB906767_gene4464	5.11e-68	213.0	COG0250@1|root,COG0250@2|Bacteria,3Y3ZR@57723|Acidobacteria,2JHU8@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_240966_1	1168034.FH5T_10545	2.37e-75	243.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_94181_2	1123399.AQVE01000003_gene2230	2.97e-35	130.0	COG3381@1|root,COG3381@2|Bacteria,1NBZG@1224|Proteobacteria,1SD7S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM cytoplasmic chaperone TorD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_94189_1	1165841.SULAR_08729	5.07e-111	320.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2YTQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_70778_1	1121875.KB907549_gene1874	1.08e-105	318.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_16641_1	439235.Dalk_1463	2.91e-177	501.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_117354_1	331869.BAL199_14437	1.21e-15	76.6	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,2U3UR@28211|Alphaproteobacteria,4BR6M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_101835_1	4098.XP_009605876.1	2.96e-16	79.3	COG2801@1|root,KOG0017@2759|Eukaryota,38889@33090|Viridiplantae,3GZ32@35493|Streptophyta,44TWH@71274|asterids	35493|Streptophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_3
k59_225609_2	996637.SGM_0524	4.8e-35	126.0	COG1522@1|root,COG1522@2|Bacteria,2GMSR@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_233521_1	743722.Sph21_2313	3.78e-53	184.0	COG3408@1|root,COG3408@2|Bacteria,4NGV6@976|Bacteroidetes,1IVWJ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
k59_194639_1	2340.JV46_03050	3.73e-86	276.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1J4SW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_156151_2	195105.CN97_06140	4.21e-07	55.5	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_117521_1	1502851.FG93_04163	5.54e-26	109.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,3JZ7W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_1533_1	1165841.SULAR_09904	2.69e-130	379.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_78838_1	367737.Abu_0453	7.37e-10	64.3	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2YTJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9,Response_reg
k59_236876_1	102125.Xen7305DRAFT_00040220	1.01e-46	157.0	COG4467@1|root,COG4467@2|Bacteria,1GQ99@1117|Cyanobacteria	1117|Cyanobacteria	S	Involved in initiation control of chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144123_1	713586.KB900536_gene1801	3.01e-44	154.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1WWRE@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k59_213624_1	68199.JNZO01000037_gene2101	1.18e-63	220.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN
k59_190378_1	1089550.ATTH01000001_gene1830	1.49e-16	78.2	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_213627_2	1165841.SULAR_02433	2.83e-67	212.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_58750_1	1122176.KB903548_gene1184	7.65e-50	178.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S binding domain protein	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
k59_136185_1	349521.HCH_03234	8.06e-73	224.0	COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria,1XN13@135619|Oceanospirillales	135619|Oceanospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_50989_1	1296416.JACB01000001_gene3282	0.000486	50.1	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia,2YKBW@290174|Aquimarina	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
k59_213628_1	1165841.SULAR_03312	3.16e-89	271.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	-	-	-	-	-	-	-	-	-	YceG
k59_236886_1	225937.HP15_1324	2.63e-91	280.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,4640Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k59_113025_2	1395587.P364_0103030	3.07e-07	56.6	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4IUSZ@91061|Bacilli,277RG@186822|Paenibacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_66568_1	1480694.DC28_12185	1.8e-18	85.9	COG0518@1|root,COG0518@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	guaA1	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k59_228925_1	395493.BegalDRAFT_3542	8.7e-69	227.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NMT1,PAS,PAS_9,Response_reg
k59_182701_1	580332.Slit_2551	4.84e-98	298.0	COG1156@1|root,COG1156@2|Bacteria,1QUQE@1224|Proteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab
k59_228926_1	1165841.SULAR_09464	1.02e-90	272.0	COG0583@1|root,COG0583@2|Bacteria,1R8CE@1224|Proteobacteria,42PKW@68525|delta/epsilon subdivisions,2YNJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_228926_2	1165841.SULAR_09459	1.28e-05	45.8	2AMMX@1|root,31CI0@2|Bacteria,1Q8WA@1224|Proteobacteria,42UGB@68525|delta/epsilon subdivisions,2YPW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105055_1	2340.JV46_04130	1.01e-107	321.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1J4KY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	iPC815.YPO2896,iYL1228.KPN_02862	Aminotran_5
k59_244467_1	1168034.FH5T_05355	3.48e-97	305.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_19901_1	2340.JV46_03460	1.89e-88	291.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_19901_2	102129.Lepto7375DRAFT_5078	7.54e-05	45.4	COG0845@1|root,COG0845@2|Bacteria,1G01U@1117|Cyanobacteria,1H98V@1150|Oscillatoriales	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_167381_1	1165841.SULAR_01085	8.72e-127	377.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_213638_1	1168034.FH5T_09800	4.95e-40	134.0	2ASAT@1|root,31HQ0@2|Bacteria,4PEUH@976|Bacteroidetes,2G01X@200643|Bacteroidia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
k59_213638_2	1168034.FH5T_09805	4.5e-28	108.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,2FX9N@200643|Bacteroidia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
k59_205845_1	1122179.KB890427_gene3877	1.73e-21	100.0	COG3385@1|root,COG3385@2|Bacteria,4P2A1@976|Bacteroidetes,1IZU1@117747|Sphingobacteriia	976|Bacteroidetes	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Tnp_DNA_bind
k59_182704_1	1217705.F900_02724	8.53e-18	82.0	COG2865@1|root,COG2865@2|Bacteria,1MXG1@1224|Proteobacteria,1RY9W@1236|Gammaproteobacteria,3NJWR@468|Moraxellaceae	1236|Gammaproteobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
k59_151537_1	1168034.FH5T_08730	2e-135	394.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,2FP2F@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
k59_27897_1	1004149.AFOE01000042_gene2771	2.05e-78	251.0	COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,1HZWZ@117743|Flavobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_221424_1	1165841.SULAR_00565	6.6e-110	329.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42Z72@68525|delta/epsilon subdivisions,2YRGJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_221424_2	387093.SUN_0830	4.03e-60	195.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42RRD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	L,D-transpeptidase catalytic domain	yafK	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_4918_1	1341181.FLJC2902T_21690	7.82e-11	62.8	COG0745@1|root,COG0745@2|Bacteria,4NGI5@976|Bacteroidetes,1HZWI@117743|Flavobacteriia,2NS62@237|Flavobacterium	976|Bacteroidetes	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_4918_2	187272.Mlg_0737	1.84e-49	170.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_82061_1	1236541.BALL01000038_gene3720	2.02e-34	123.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,2QBY4@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM thioesterase superfamily protein	ybgC	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_0747,iSDY_1059.SDY_0684	4HBT
k59_82061_2	1046724.KB889892_gene664	6.72e-31	117.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,464S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_89664_1	163908.KB235896_gene3938	2.76e-45	169.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_151548_1	387093.SUN_1173	1.06e-89	269.0	COG1752@1|root,COG1752@2|Bacteria,1Q43H@1224|Proteobacteria,42Y72@68525|delta/epsilon subdivisions,2YR75@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_244485_2	1168034.FH5T_12460	2.36e-88	274.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NEXG@976|Bacteroidetes,2G2WR@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_221427_1	1278307.KB907072_gene2701	3.26e-128	371.0	COG1637@1|root,COG1637@2|Bacteria	2|Bacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
k59_167394_2	396588.Tgr7_0319	2.45e-59	192.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1WX0V@135613|Chromatiales	135613|Chromatiales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_136210_1	1318628.MARLIPOL_12944	1e-30	125.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
k59_58781_1	288000.BBta_0206	8.53e-65	219.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JQNW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
k59_167395_1	283942.IL2343	1e-23	104.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QGMB@267893|Idiomarinaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_35875_1	1165841.SULAR_06738	1.56e-31	121.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42Z4X@68525|delta/epsilon subdivisions,2YRD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_35875_2	1165841.SULAR_06733	5.33e-51	176.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_105071_1	1335757.SPICUR_01585	8.52e-163	469.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1WWX1@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_198358_1	886379.AEWI01000013_gene2129	3.15e-85	258.0	COG0863@1|root,COG0863@2|Bacteria,4NID2@976|Bacteroidetes,2FV9W@200643|Bacteroidia	976|Bacteroidetes	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_27910_1	1082933.MEA186_00736	5.82e-24	104.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,2UEEB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_205868_1	395493.BegalDRAFT_0529	3.03e-24	98.2	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria	1224|Proteobacteria	U	general secretion pathway protein G	gspG2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_205868_2	494416.AYXN01000017_gene1361	7.57e-12	66.2	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,3NN5T@468|Moraxellaceae	1236|Gammaproteobacteria	U	general secretion pathway protein	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_58782_1	1165841.SULAR_05673	1.76e-101	306.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_58782_2	1165841.SULAR_05678	2.04e-66	206.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_174791_1	1122917.KB899660_gene1997	3.35e-43	159.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,26TZM@186822|Paenibacillaceae	91061|Bacilli	E	oligoendopeptidase F	yjbG	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_136214_1	1525715.IX54_12045	1.27e-165	488.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,2PVP8@265|Paracoccus	28211|Alphaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.7.2.3	ko:K07812,ko:K08351	ko00780,ko01100,map00780,map01100	-	R10127	RC03056	ko00000,ko00001,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding
k59_144172_1	935863.AWZR01000005_gene2427	2.42e-37	139.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1X3X9@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_198365_1	1123261.AXDW01000010_gene292	8.92e-54	187.0	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,1RNZA@1236|Gammaproteobacteria,1X9PU@135614|Xanthomonadales	135614|Xanthomonadales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74592_1	89187.ISM_11105	3.17e-25	103.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2TRJ3@28211|Alphaproteobacteria,46P4M@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0687 Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_244765_1	1165841.SULAR_04808	2.16e-27	104.0	2ENG1@1|root,33G3G@2|Bacteria,1NPIZ@1224|Proteobacteria,42ZV2@68525|delta/epsilon subdivisions,2YRT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_244765_2	1165841.SULAR_04803	8.56e-147	415.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,42MG5@68525|delta/epsilon subdivisions,2YN7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k59_198555_1	977880.RALTA_A2260	6.36e-26	102.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,1K11F@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_198555_2	349124.Hhal_1659	2.78e-13	70.1	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1WW40@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_28146_1	706587.Desti_0274	1.11e-17	87.4	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MR2Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_174947_1	945713.IALB_0798	5.29e-08	57.4	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
k59_151837_1	565045.NOR51B_2532	2.44e-72	224.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	ACP_PD
k59_159636_2	493475.GARC_0183	2.85e-19	85.1	COG4232@1|root,COG4232@2|Bacteria,1QWZ3@1224|Proteobacteria,1T30Q@1236|Gammaproteobacteria,46BSV@72275|Alteromonadaceae	1236|Gammaproteobacteria	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_151838_1	1165841.SULAR_00410	2.07e-19	81.6	COG3030@1|root,COG3030@2|Bacteria	2|Bacteria	S	protein affecting phage T7 exclusion by the F plasmid	fxsA	-	2.3.3.13	ko:K01649,ko:K07113	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	FxsA
k59_151838_2	1165841.SULAR_00405	2.19e-90	278.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_15161_1	1026882.MAMP_00247	1.36e-88	275.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales	72273|Thiotrichales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_139103_1	1232437.KL662067_gene2494	6.18e-42	139.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42TQU@68525|delta/epsilon subdivisions,2WQ3A@28221|Deltaproteobacteria,2MNQM@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PPIC-type PPIASE domain	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SseB
k59_139106_1	655815.ZPR_2447	2.48e-51	183.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_84898_1	1237149.C900_03021	1.4e-123	369.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_239828_1	232346.JHQL01000002_gene1086	7.26e-21	98.2	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XICX@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_23146_1	313596.RB2501_11032	3.39e-83	254.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1HXPA@117743|Flavobacteriia	976|Bacteroidetes	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_139108_1	243277.VC_A0483	3.87e-62	197.0	2BY42@1|root,32R2K@2|Bacteria,1MZU9@1224|Proteobacteria,1S84F@1236|Gammaproteobacteria,1Y1MJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_216512_1	765913.ThidrDRAFT_2339	3.79e-86	270.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_216512_2	1195236.CTER_3367	1.25e-05	50.4	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
k59_231767_1	1165841.SULAR_04567	1.75e-64	212.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,42PHS@68525|delta/epsilon subdivisions,2YQ45@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Paraquat-inducible protein B	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
k59_231767_2	1165841.SULAR_04562	3.7e-34	122.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	MA20_38065	-	-	ko:K02067,ko:K09857,ko:K18480	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27,3.A.1.27.1	-	-	ABC_trans_aux,MlaD
k59_46351_1	323261.Noc_2921	4.58e-104	317.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales	135613|Chromatiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_154579_1	1192868.CAIU01000033_gene4184	1.57e-44	150.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VFYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_231768_1	387093.SUN_0014	2.82e-25	103.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_231768_2	1499683.CCFF01000017_gene2259	1.21e-15	77.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_154580_1	48698.ENSPFOP00000030735	1.08e-22	103.0	COG2103@1|root,2QS2J@2759|Eukaryota,38ECQ@33154|Opisthokonta,3BF6B@33208|Metazoa,3CZ2P@33213|Bilateria,489SP@7711|Chordata,496D1@7742|Vertebrata,49VCS@7898|Actinopterygii	33208|Metazoa	S	Glucokinase (hexokinase 4) regulator	GCKR	GO:0000060,GO:0001678,GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006109,GO:0006110,GO:0006140,GO:0006606,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008150,GO:0008152,GO:0009593,GO:0009730,GO:0009732,GO:0009743,GO:0009746,GO:0009749,GO:0009750,GO:0009889,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010033,GO:0010562,GO:0010563,GO:0010675,GO:0010676,GO:0010677,GO:0010906,GO:0015031,GO:0015833,GO:0017038,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019725,GO:0019899,GO:0019904,GO:0030234,GO:0030246,GO:0030808,GO:0030811,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031329,GO:0031974,GO:0031981,GO:0033036,GO:0033131,GO:0033132,GO:0033133,GO:0033365,GO:0033500,GO:0033673,GO:0033674,GO:0034284,GO:0034287,GO:0034504,GO:0034613,GO:0034641,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042592,GO:0042593,GO:0042886,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043467,GO:0043470,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045912,GO:0045913,GO:0045936,GO:0045937,GO:0046415,GO:0046483,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051169,GO:0051170,GO:0051171,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051234,GO:0051338,GO:0051347,GO:0051348,GO:0051594,GO:0051606,GO:0051641,GO:0051649,GO:0055082,GO:0055088,GO:0055090,GO:0062012,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070095,GO:0070328,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0072521,GO:0072594,GO:0080090,GO:0097367,GO:0098772,GO:1900371,GO:1900542,GO:1901360,GO:1901564,GO:1901700,GO:1903299,GO:1903300,GO:1903301,GO:1903578,GO:2001169	-	-	-	-	-	-	-	-	-	-	-
k59_216518_1	1165841.SULAR_09364	1e-105	326.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_84908_1	904296.HMPREF9124_0899	2.18e-08	61.2	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,2PR0I@265975|Oribacterium	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_23154_1	1265505.ATUG01000001_gene4109	4.8e-57	185.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria,2MIQE@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_139118_1	111781.Lepto7376_2297	8.19e-78	249.0	COG0069@1|root,COG2146@1|root,COG0069@2|Bacteria,COG2146@2|Bacteria,1G0XM@1117|Cyanobacteria,1H8GB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_231778_1	1500893.JQNB01000001_gene1545	1.93e-43	153.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,1RXYM@1236|Gammaproteobacteria,1X3GY@135614|Xanthomonadales	135614|Xanthomonadales	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
k59_162474_1	1168034.FH5T_17615	2.38e-08	55.1	28H5M@1|root,2Z7I7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162474_2	643867.Ftrac_0468	1.12e-34	124.0	COG1846@1|root,COG1846@2|Bacteria,4NQUD@976|Bacteroidetes,47QAI@768503|Cytophagia	976|Bacteroidetes	K	PFAM MarR family	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_15196_1	28377.ENSACAP00000014400	1.4e-13	77.0	28HX2@1|root,2QQ7Z@2759|Eukaryota,38DFP@33154|Opisthokonta,3BGZ5@33208|Metazoa,3CUDF@33213|Bilateria,483BS@7711|Chordata,496VF@7742|Vertebrata	33208|Metazoa	T	Pregnancy-associated plasma protein-A	PAPPA2	GO:0001558,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009987,GO:0016787,GO:0019538,GO:0040008,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051128,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.24.79	ko:K07762,ko:K08647	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF4215,Laminin_G_3,Notch,Peptidase_M43,Sushi
k59_15204_1	458233.MCCL_1192	1.59e-10	65.5	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,4GXW8@90964|Staphylococcaceae	91061|Bacilli	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
k59_139126_1	768671.ThimaDRAFT_3239	2.26e-29	118.0	COG2244@1|root,COG2244@2|Bacteria,1PF64@1224|Proteobacteria,1TKCZ@1236|Gammaproteobacteria,1X1Y8@135613|Chromatiales	135613|Chromatiales	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_139132_1	1165841.SULAR_08442	1.86e-07	52.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_139132_2	1165841.SULAR_08437	3.24e-67	204.0	COG0011@1|root,COG0011@2|Bacteria,1N0UT@1224|Proteobacteria,43B8R@68525|delta/epsilon subdivisions,2YT6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_216541_1	1168034.FH5T_14750	4.31e-91	280.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
k59_92717_1	909613.UO65_5325	3.91e-52	185.0	COG0318@1|root,COG0318@2|Bacteria,2IBJ8@201174|Actinobacteria,4EA9B@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_216546_2	1042209.HK44_006705	2.36e-19	88.6	COG2267@1|root,COG2267@2|Bacteria,1QXQT@1224|Proteobacteria	1224|Proteobacteria	I	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
k59_139155_1	860228.Ccan_03930	0.000617	43.9	COG0741@1|root,COG0741@2|Bacteria,4NMIF@976|Bacteroidetes,1I1GE@117743|Flavobacteriia,1ER84@1016|Capnocytophaga	976|Bacteroidetes	M	Peptidoglycan-binding protein LysM	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108168_1	395493.BegalDRAFT_1992	4.34e-36	137.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Type I restriction-modification system methyltransferase subunit	hsdM	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_84949_1	2340.JV46_12710	3.07e-85	278.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1J4Y8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_15256_1	1165841.SULAR_04477	3.48e-18	85.1	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,HD_5,Hpt,Response_reg
k59_15256_2	1165841.SULAR_04472	8.55e-95	282.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_46394_1	316275.VSAL_I2775	7.33e-56	188.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XU48@135623|Vibrionales	135623|Vibrionales	O	HflC and HflK could encode or regulate a protease	hflK	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_116056_2	1168034.FH5T_09440	6.83e-74	223.0	COG0346@1|root,COG0346@2|Bacteria,4NQQA@976|Bacteroidetes	976|Bacteroidetes	E	glyoxalase	gloA	-	4.4.1.5	ko:K01759,ko:K03827	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Glyoxalase,Glyoxalase_4
k59_116056_3	485918.Cpin_6614	4.02e-05	45.1	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1IR7H@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k59_216582_1	713586.KB900536_gene609	1.61e-47	166.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales	135613|Chromatiales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
k59_15262_1	2340.JV46_09930	4.68e-115	338.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1J4PY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	iYL1228.KPN_03597,ic_1306.c3945	polyprenyl_synt
k59_23181_1	1125863.JAFN01000001_gene3368	3.45e-119	359.0	COG2414@1|root,COG2414@2|Bacteria,1R5AG@1224|Proteobacteria,42NHF@68525|delta/epsilon subdivisions,2WK3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	bamB-1	-	1.2.7.5	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	M00309,M00541	R08571,R10961	RC00242,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_46406_1	765911.Thivi_1082	1.09e-39	139.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1S81I@1236|Gammaproteobacteria,1WYKH@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_177866_1	1458275.AZ34_11340	3.68e-62	212.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1
k59_177867_1	348780.NP_2656A	2.04e-21	98.6	COG0642@1|root,arCOG02354@1|root,arCOG02376@1|root,arCOG02389@1|root,arCOG06796@1|root,arCOG02354@2157|Archaea,arCOG02376@2157|Archaea,arCOG02389@2157|Archaea,arCOG06408@2157|Archaea,arCOG06796@2157|Archaea,2Y7UQ@28890|Euryarchaeota	28890|Euryarchaeota	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
k59_46413_1	553217.ENHAE0001_0744	1.54e-05	47.8	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,3NJAC@468|Moraxellaceae	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280	Aldedh
k59_46413_2	1286631.X805_01850	1.51e-07	57.4	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,1KJ0R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k59_23193_1	765914.ThisiDRAFT_2587	4.94e-33	115.0	28IGK@1|root,2Z8I1@2|Bacteria,1RAH7@1224|Proteobacteria,1RPTY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_23193_2	279714.FuraDRAFT_0233	2.48e-18	84.7	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,2KQ8G@206351|Neisseriales	206351|Neisseriales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_84972_1	1123284.KB899043_gene142	1.1e-62	219.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26NIH@186821|Sporolactobacillaceae	91061|Bacilli	L	Single-strand DNA-specific exonuclease, C terminal domain	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
k59_15269_1	794846.AJQU01000089_gene837	6.95e-24	105.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BCMT@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16
k59_108183_1	713587.THITH_01400	6.86e-109	323.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_46417_1	1519464.HY22_07245	1.96e-74	230.0	COG4783@1|root,COG4783@2|Bacteria,1FFG5@1090|Chlorobi	1090|Chlorobi	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_23198_1	1123057.P872_08485	3.06e-09	61.2	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47MUU@768503|Cytophagia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_162700_1	927677.ALVU02000001_gene4534	6.39e-42	149.0	COG4632@1|root,COG4632@2|Bacteria,1G25D@1117|Cyanobacteria	1117|Cyanobacteria	G	periplasmic protein (DUF2233)	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
k59_46665_1	1168034.FH5T_21945	8.05e-41	142.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46665_2	1168034.FH5T_21940	6.33e-38	133.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,2FMM4@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_15746_1	398720.MED217_08590	2.83e-17	86.7	COG0419@1|root,COG3291@1|root,COG0419@2|Bacteria,COG3291@2|Bacteria,4NI5F@976|Bacteroidetes,1I1KV@117743|Flavobacteriia	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,PKD
k59_100894_1	384676.PSEEN0254	1.1e-67	218.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RNEQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate	wecE	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	iE2348C_1286.E2348C_4092,iEC55989_1330.EC55989_4263,iECIAI1_1343.ECIAI1_3978,iECIAI39_1322.ECIAI39_2996,iECO103_1326.ECO103_4373,iECO111_1330.ECO111_4617,iECO26_1355.ECO26_4795,iECUMN_1333.ECUMN_4316,iECW_1372.ECW_m4089,iEKO11_1354.EKO11_4565,iSSON_1240.SSON_3963,iWFL_1372.ECW_m4089	DegT_DnrJ_EryC1
k59_15749_1	933262.AXAM01000052_gene1988	1.22e-175	496.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_155054_1	876044.IMCC3088_1003	1.2e-19	88.6	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1J4VG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1509 Lysine 2,3-aminomutase	epmB	GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569	Fer4_12,Fer4_14,Radical_SAM
k59_123971_1	1117647.M5M_12180	6.81e-91	280.0	28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,1J92F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100899_1	1279019.ARQK01000039_gene457	4.64e-87	270.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales	135613|Chromatiales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_77631_1	1122179.KB890443_gene1182	8.11e-18	87.8	COG0702@1|root,COG0702@2|Bacteria,4NEDB@976|Bacteroidetes,1IRMH@117747|Sphingobacteriia	976|Bacteroidetes	GM	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_216988_1	563040.Saut_1275	2.62e-29	120.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_224683_1	7668.SPU_017953-tr	8e-54	191.0	2CMGD@1|root,2QQ9V@2759|Eukaryota,39B3J@33154|Opisthokonta,3BKG5@33208|Metazoa,3CTR5@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2
k59_178268_1	1453501.JELR01000001_gene2871	9.39e-08	54.3	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,1RQAT@1236|Gammaproteobacteria,464CR@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_193720_1	247634.GPB2148_1066	7.83e-99	310.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1J4T4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_26724_1	572477.Alvin_1118	5.15e-54	181.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_65373_1	1163745.HCD_08330	2.65e-61	205.0	COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,42U0V@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k59_166151_1	1242864.D187_001081	0.000134	50.1	COG3170@1|root,COG3170@2|Bacteria,1R2XT@1224|Proteobacteria,43DHQ@68525|delta/epsilon subdivisions,2X8PG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
k59_204654_1	28229.ND2E_0958	1.78e-44	149.0	COG0789@1|root,COG0789@2|Bacteria,1MWN0@1224|Proteobacteria,1RQA6@1236|Gammaproteobacteria,2Q83T@267889|Colwelliaceae	1236|Gammaproteobacteria	K	helix_turn_helix, mercury resistance	mta_1	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
k59_204654_2	1288826.MSNKSG1_11608	4.25e-07	51.6	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,4641J@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG3118 Thioredoxin domain-containing protein	ybbN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_220278_1	706587.Desti_3166	3.81e-61	196.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJIS@28221|Deltaproteobacteria,2MRGF@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_220278_2	706587.Desti_3167	1.43e-16	77.8	COG4177@1|root,COG4177@2|Bacteria,1NNMV@1224|Proteobacteria,42PQV@68525|delta/epsilon subdivisions,2WJDV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_34653_1	1168034.FH5T_04170	1.45e-163	496.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_166162_1	880073.Calab_0050	7.19e-05	51.6	COG1332@1|root,COG1332@2|Bacteria,2NRMG@2323|unclassified Bacteria	2|Bacteria	L	RAMP superfamily	-	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k59_189205_1	1347392.CCEZ01000020_gene918	9.01e-14	73.6	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,36DGG@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_80993_1	1401067.HMPREF0872_03140	8.24e-32	123.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,4H28W@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_80993_2	1121920.AUAU01000022_gene2455	4.39e-91	280.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria	57723|Acidobacteria	J	PFAM tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_57577_1	1165841.SULAR_10364	3.64e-146	451.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_80994_1	1121904.ARBP01000011_gene1465	1.27e-143	435.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_220289_1	983545.Glaag_3204	2.28e-70	235.0	28HYP@1|root,2Z842@2|Bacteria,1N96P@1224|Proteobacteria,1RQCQ@1236|Gammaproteobacteria,4659S@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49850_1	1173026.Glo7428_1436	1.11e-05	53.5	COG0110@1|root,COG2203@1|root,COG0110@2|Bacteria,COG2203@2|Bacteria,1G2PV@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_34664_1	1278073.MYSTI_01750	9.9e-23	102.0	COG0308@1|root,COG0308@2|Bacteria,1PTWJ@1224|Proteobacteria,42YQD@68525|delta/epsilon subdivisions,2WU66@28221|Deltaproteobacteria,2YXEH@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_42267_1	1165841.SULAR_05648	7.77e-127	375.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	glnL	-	-	ko:K07719	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,TPR_16,TPR_19,TPR_8,YcbB
k59_227800_1	452637.Oter_0823	1.61e-37	146.0	COG4191@1|root,COG4191@2|Bacteria,46TZW@74201|Verrucomicrobia,3K9EP@414999|Opitutae	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4
k59_173721_1	709032.Sulku_1827	1.26e-06	47.0	2EH74@1|root,33AYY@2|Bacteria,1P07W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49862_1	761193.Runsl_4865	3.58e-70	227.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,47JGD@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k59_57586_1	1353531.AZNX01000005_gene3261	4.97e-76	256.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_119705_1	420662.Mpe_A0243	1.94e-17	86.3	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,1KJV8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_119705_2	2340.JV46_22790	2.2e-42	149.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1J5SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	ramA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_227818_1	1229755.K7R2J6_9CAUD	1.28e-25	112.0	4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses  no RNA stage,4QQ4N@28883|Caudovirales	28883|Caudovirales	S	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_227818_2	509191.AEDB02000035_gene2202	8.91e-05	45.4	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WHXU@541000|Ruminococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_119713_1	1463887.KL589991_gene1228	5.58e-35	136.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria	201174|Actinobacteria	KLT	Serine threonine protein kinase	pksC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_57594_1	765914.ThisiDRAFT_1082	9.43e-12	63.9	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_57594_2	1407650.BAUB01000007_gene1568	7.68e-24	98.6	COG0264@1|root,COG0264@2|Bacteria,1G00T@1117|Cyanobacteria,1GYCT@1129|Synechococcus	1117|Cyanobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_112000_1	1168034.FH5T_09165	1.35e-83	255.0	COG0668@1|root,COG0668@2|Bacteria,4NFX6@976|Bacteroidetes,2FR5Q@200643|Bacteroidia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_112000_2	1168034.FH5T_09170	5.04e-05	43.5	COG3613@1|root,COG3613@2|Bacteria	2|Bacteria	F	nucleoside 2-deoxyribosyltransferase	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
k59_204676_1	264402.Cagra.0259s0017.1.p	1.98e-22	93.2	2CKHQ@1|root,2S5E8@2759|Eukaryota,37WKE@33090|Viridiplantae,3GKNN@35493|Streptophyta	35493|Streptophyta	S	BEST Arabidopsis thaliana protein match is Mitovirus RNA-dependent RNA polymerase (TAIR	-	-	-	-	-	-	-	-	-	-	-	-	Mitovir_RNA_pol
k59_212454_1	1250232.JQNJ01000001_gene226	1.87e-58	190.0	COG1215@1|root,COG1215@2|Bacteria,4NFUA@976|Bacteroidetes,1HY1H@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_11356_1	2340.JV46_16810	5.5e-40	149.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1J4R4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_227823_1	1165841.SULAR_06588	2.32e-30	117.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YMGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_57929_1	402881.Plav_0362	1.63e-16	81.6	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2U7YI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
k59_135342_1	317936.Nos7107_4775	1.62e-22	102.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1G027@1117|Cyanobacteria,1HN0K@1161|Nostocales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg,Trans_reg_C
k59_127829_1	756067.MicvaDRAFT_3749	1.26e-25	107.0	COG1215@1|root,COG1215@2|Bacteria,1G8C4@1117|Cyanobacteria,1HHUN@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_189544_1	1122599.AUGR01000011_gene4080	1.12e-121	367.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XHBT@135619|Oceanospirillales	135619|Oceanospirillales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_88937_1	1121931.AUHG01000010_gene820	3.88e-47	167.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_4106_1	1123247.AUIJ01000001_gene1731	2.21e-113	333.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_57933_1	3880.AES93933	3.01e-24	102.0	COG5272@1|root,KOG2381@1|root,KOG0001@2759|Eukaryota,KOG2381@2759|Eukaryota,37RMX@33090|Viridiplantae,3G9F1@35493|Streptophyta,4JGUX@91835|fabids	35493|Streptophyta	OT	Phosphatidylinositol 4-kinase gamma 2-like	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0009651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase,ubiquitin
k59_73462_1	314285.KT71_12215	2.91e-32	132.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
k59_65705_1	497964.CfE428DRAFT_5438	5.66e-31	119.0	COG0657@1|root,COG0657@2|Bacteria,46U1I@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_120042_1	1168034.FH5T_04235	3.64e-32	112.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_135348_1	935567.JAES01000020_gene552	7.66e-33	114.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1X7FD@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_135348_2	1121116.KB894768_gene2028	1.63e-16	75.5	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,4ADG9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_50199_1	1296415.JACC01000035_gene1254	1.95e-18	88.6	COG1361@1|root,COG1361@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG
k59_73466_1	1195246.AGRI_12781	7.14e-52	186.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4645Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_220618_2	1120985.AUMI01000001_gene2158	1.1e-31	125.0	COG3299@1|root,COG3299@2|Bacteria,1TQXP@1239|Firmicutes,4H5RU@909932|Negativicutes	909932|Negativicutes	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_181957_1	244447.XP_008335319.1	3.25e-45	153.0	COG0317@1|root,KOG1157@2759|Eukaryota,39Y6C@33154|Opisthokonta,3BNBB@33208|Metazoa,3CWZI@33213|Bilateria,4816Y@7711|Chordata,497H9@7742|Vertebrata,49QKW@7898|Actinopterygii	33208|Metazoa	T	HD domain containing 3	HDDC3	GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008893,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009154,GO:0009164,GO:0009166,GO:0009259,GO:0009261,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0015971,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0031667,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034035,GO:0034037,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.7.2	ko:K21138	ko00230,map00230	-	R00336	RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
k59_181957_2	1121930.AQXG01000009_gene279	1.5e-22	97.8	COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes	976|Bacteroidetes	E	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k59_120050_1	768671.ThimaDRAFT_3019	1e-30	115.0	2BZBC@1|root,32R4Q@2|Bacteria,1RICW@1224|Proteobacteria,1SQD2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_158590_1	1165841.SULAR_08247	1.37e-49	176.0	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11676_1	94122.Shewana3_2005	3.1e-08	60.1	COG1922@1|root,COG2148@1|root,COG1922@2|Bacteria,COG2148@2|Bacteria,1N1HD@1224|Proteobacteria,1RP6P@1236|Gammaproteobacteria,2QAQA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TIGRFAM glycosyl transferase, WecB TagA CpsF family	gumM	-	2.4.1.187	ko:K05946,ko:K13660	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Bac_transf,Glyco_tran_WecB
k59_96721_2	2340.JV46_07970	3.34e-56	187.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1J4E0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k59_35012_2	749222.Nitsa_0520	6.57e-114	339.0	28K4S@1|root,2Z9TM@2|Bacteria,1N4AQ@1224|Proteobacteria,42PSN@68525|delta/epsilon subdivisions,2YMP7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_35012_3	749222.Nitsa_0519	9.41e-17	77.4	COG1136@1|root,COG1136@2|Bacteria,1NVQS@1224|Proteobacteria,43AKA@68525|delta/epsilon subdivisions,2YM7X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_146833_2	1165841.SULAR_09099	1.4e-145	412.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,42NNI@68525|delta/epsilon subdivisions,2YNBH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,Methyltransf_31
k59_192740_1	857087.Metme_4085	3.35e-89	270.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1XE5V@135618|Methylococcales	135618|Methylococcales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_146838_1	768706.Desor_1103	2.49e-29	121.0	COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,25E5Z@186801|Clostridia,2613F@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	lytS	-	2.7.13.3	ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase
k59_200588_1	1168034.FH5T_07830	1.17e-87	286.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,2FXCC@200643|Bacteroidia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_45617_1	1004149.AFOE01000018_gene591	3.59e-123	363.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
k59_45618_1	1168034.FH5T_09560	2.09e-88	282.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,2FN6Z@200643|Bacteroidia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_76747_1	34506.g2089	3.02e-39	147.0	COG2933@1|root,2S28J@2759|Eukaryota,3AQB8@33154|Opisthokonta,3BXJX@33208|Metazoa,3DF58@33213|Bilateria	33208|Metazoa	J	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	FtsJ,HTH_1,LysR_substrate
k59_61150_1	688270.Celal_1844	7.68e-15	72.8	COG0457@1|root,COG0457@2|Bacteria,4NM69@976|Bacteroidetes,1I0UE@117743|Flavobacteriia,1F8JR@104264|Cellulophaga	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61150_2	1463936.JOJI01000017_gene7577	0.000124	46.2	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria	201174|Actinobacteria	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_153897_1	1408324.JNJK01000009_gene2342	4.58e-05	47.8	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,27I5A@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_100035_1	1121939.L861_22545	1.19e-43	164.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XNJ7@135619|Oceanospirillales	135619|Oceanospirillales	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
k59_45625_1	1165841.SULAR_04517	6.91e-43	148.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,42S9D@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_208099_2	118168.MC7420_1011	3.2e-33	126.0	COG0642@1|root,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1H7ER@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_130885_1	1168034.FH5T_12535	6.29e-96	288.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,2FNMC@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_215788_1	511062.GU3_10950	2.02e-73	224.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1Y3RW@135624|Aeromonadales	135624|Aeromonadales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_223711_1	1165841.SULAR_05873	2.11e-141	400.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2YN8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_223711_2	387093.SUN_1812	1.64e-29	113.0	COG3869@1|root,COG3869@2|Bacteria,1R4ST@1224|Proteobacteria,42MP2@68525|delta/epsilon subdivisions,2YNUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP:guanido phosphotransferase, N-terminal domain	-	-	2.7.3.2,2.7.3.3	ko:K00933,ko:K00934	ko00330,ko01100,map00330,map01100	M00047	R00554,R01881	RC00002,RC00203	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ATP-gua_Ptrans,ATP-gua_PtransN
k59_246736_1	225937.HP15_1324	4.63e-101	304.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,4640Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k59_231053_1	1165841.SULAR_03632	1.58e-131	380.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_107351_1	1408473.JHXO01000001_gene1977	7.97e-06	54.7	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_7083_1	485918.Cpin_5230	7.56e-18	80.5	COG3279@1|root,COG3279@2|Bacteria,4NFZT@976|Bacteroidetes,1IRIX@117747|Sphingobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_7083_2	1380384.JADN01000007_gene1657	7.72e-36	134.0	COG2972@1|root,COG2972@2|Bacteria,4NDU5@976|Bacteroidetes,1HZB6@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_61170_1	411463.EUBVEN_00392	1.67e-06	55.8	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25WEQ@186806|Eubacteriaceae	186801|Clostridia	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
k59_185006_1	1168034.FH5T_11850	2.33e-100	308.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,2FM3Y@200643|Bacteroidia	976|Bacteroidetes	F	Class II glutamine amidotransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
k59_76753_1	519989.ECTPHS_04334	6.23e-101	307.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_45636_1	1449347.JQLN01000005_gene3718	4.08e-12	68.9	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,2M1WH@2063|Kitasatospora	201174|Actinobacteria	HP	ThiF family	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_30325_1	1165841.SULAR_09089	1.36e-53	179.0	COG0642@1|root,COG2205@2|Bacteria,1QZF7@1224|Proteobacteria,43CIH@68525|delta/epsilon subdivisions,2YTD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_30325_2	1165841.SULAR_09094	4.65e-182	514.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_146847_2	1121935.AQXX01000099_gene1223	1.79e-80	248.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.5	ko:K07025,ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_107370_1	929558.SMGD1_1328	1.21e-86	275.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2YNIK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,dCache_1
k59_153912_1	765910.MARPU_15380	8.82e-21	100.0	COG0651@1|root,COG0651@2|Bacteria,1N6BY@1224|Proteobacteria,1RR4C@1236|Gammaproteobacteria,1WWFY@135613|Chromatiales	135613|Chromatiales	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Proton_antipo_M
k59_100039_1	436114.SYO3AOP1_1757	2.4e-90	278.0	COG0677@1|root,COG0677@2|Bacteria,2G4GH@200783|Aquificae	200783|Aquificae	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_45640_1	272568.GDI1811	7.92e-22	94.4	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,2JPJW@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_247135_2	1168034.FH5T_19050	3.27e-30	110.0	COG3118@1|root,COG3118@2|Bacteria,4NWFX@976|Bacteroidetes,2FUZC@200643|Bacteroidia	976|Bacteroidetes	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_131352_1	187272.Mlg_1097	2.29e-71	236.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WW1G@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_92332_1	1442599.JAAN01000047_gene2928	1.65e-70	229.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1X497@135614|Xanthomonadales	135614|Xanthomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_201041_1	1120950.KB892762_gene5508	4.79e-07	49.3	COG4274@1|root,COG4274@2|Bacteria,2HWQ8@201174|Actinobacteria,4DW30@85009|Propionibacteriales	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
k59_239583_1	395493.BegalDRAFT_2346	1.08e-50	182.0	COG0784@1|root,COG4251@1|root,COG0784@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
k59_216191_2	714943.Mucpa_3589	4.16e-23	98.2	COG1835@1|root,COG1835@2|Bacteria,4NIVR@976|Bacteroidetes,1ITNG@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_208527_1	1198452.Jab_2c02510	6.59e-30	114.0	2EMEM@1|root,33F3F@2|Bacteria,1NK08@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_30763_1	1123517.JOMR01000001_gene862	3.29e-79	255.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,45ZT6@72273|Thiotrichales	72273|Thiotrichales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_193157_1	1047013.AQSP01000122_gene2249	1.27e-88	279.0	28NDD@1|root,2ZBG6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_185447_1	96561.Dole_2580	1.21e-50	174.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MHY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k59_185447_2	36874.HQ34_02000	1.02e-46	164.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,2FMVE@200643|Bacteroidia,22W9U@171551|Porphyromonadaceae	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_208531_1	1565129.JSFF01000023_gene2781	2.37e-56	185.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,2QA1E@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	GO:0000150,GO:0000976,GO:0000984,GO:0000985,GO:0000988,GO:0000990,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006310,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009009,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031421,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2001141	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k59_177448_1	387093.SUN_1511	1.36e-51	177.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42YPX@68525|delta/epsilon subdivisions,2YRHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_177448_2	387093.SUN_1512	4.47e-39	138.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2YQN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_131360_1	690597.JH730985_gene871	1.57e-93	291.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1YMQ7@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	GMC family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_61581_1	1392498.JQLH01000001_gene2319	4.49e-69	228.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia,2PGH2@252356|Maribacter	976|Bacteroidetes	L	AAA ATPase domain	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_115705_1	506534.Rhein_2924	0.000332	41.2	2EHRX@1|root,33BHN@2|Bacteria,1NG91@1224|Proteobacteria,1SGIP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115705_2	1278309.KB907100_gene2194	6.37e-31	122.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales	135619|Oceanospirillales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_7556_1	313596.RB2501_07485	1.66e-66	226.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_30773_1	2340.JV46_03170	9.39e-66	214.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,1J9P0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_162126_1	1165841.SULAR_09149	1.06e-104	303.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,42RGH@68525|delta/epsilon subdivisions,2YP5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_208537_1	2340.JV46_20620	5.84e-34	131.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1J4HS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
k59_208537_2	981336.F944_02457	7.08e-09	57.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,3NJKS@468|Moraxellaceae	1236|Gammaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_224116_1	1117318.PRUB_08145	7.65e-146	423.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,2PZNU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	involved in the control of DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_77271_1	926562.Oweho_3134	1.28e-78	260.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PBJJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_201055_1	1123399.AQVE01000052_gene330	1.32e-21	95.1	COG1432@1|root,COG1432@2|Bacteria,1RFW3@1224|Proteobacteria,1S0QM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k59_193171_1	1121129.KB903359_gene1566	7.34e-10	65.5	COG3137@1|root,COG3137@2|Bacteria,4NRXD@976|Bacteroidetes,2FNZ5@200643|Bacteroidia,22XMW@171551|Porphyromonadaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_154344_1	1499967.BAYZ01000184_gene4583	3.78e-102	306.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k59_185465_1	1183377.Py04_0089	5.1e-09	61.6	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,242VX@183968|Thermococci	183968|Thermococci	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	ubiA	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
k59_77274_1	1280949.HAD_00355	2.02e-77	254.0	COG0668@1|root,COG2823@1|root,COG0668@2|Bacteria,COG2823@2|Bacteria,1MW1F@1224|Proteobacteria,2TTVC@28211|Alphaproteobacteria,43X5A@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,MS_channel
k59_53798_1	1134474.O59_004307	1.15e-41	152.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RZ3X@1236|Gammaproteobacteria,1FHSJ@10|Cellvibrio	1236|Gammaproteobacteria	S	protein and some similarities with VgrG protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k59_53798_2	1134474.O59_004308	2.57e-29	108.0	COG3157@1|root,COG3157@2|Bacteria,1R9GB@1224|Proteobacteria,1RYJ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hemolysin-coregulated protein	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
k59_138852_1	411479.BACUNI_02479	1.48e-15	79.7	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,2FMR0@200643|Bacteroidia,4AMZU@815|Bacteroidaceae	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_242793_1	1168034.FH5T_10630	1.12e-94	285.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_196546_1	1095769.CAHF01000022_gene432	1.07e-49	186.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_126903_1	270374.MELB17_01135	4.6e-51	170.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,465E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_64853_1	1165841.SULAR_01788	6.23e-66	216.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_41710_1	1165841.SULAR_05948	1.61e-112	345.0	28N8G@1|root,2ZBCV@2|Bacteria,1NMB1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_18237_1	497964.CfE428DRAFT_6041	3.88e-08	56.6	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,46UMD@74201|Verrucomicrobia	2|Bacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
k59_103467_1	1123487.KB892835_gene3299	2.56e-08	55.5	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2VJR1@28216|Betaproteobacteria,2KW7X@206389|Rhodocyclales	206389|Rhodocyclales	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
k59_49327_1	561229.Dd1591_1467	8.63e-34	135.0	COG1205@1|root,COG1205@2|Bacteria,1QTSR@1224|Proteobacteria,1T1FX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF1998,Helicase_C
k59_196549_1	1049564.TevJSym_ad00630	1.2e-88	271.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,1RNPV@1236|Gammaproteobacteria,1J4JU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	iSDY_1059.SDY_2242,iSF_1195.SF2059,iSFxv_1172.SFxv_2293,iS_1188.S2169	DBI_PRT
k59_103468_1	927658.AJUM01000043_gene771	8e-75	229.0	COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,2G1HP@200643|Bacteroidia,3XKV6@558415|Marinilabiliaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_235230_1	1165841.SULAR_00120	8.69e-118	367.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_211837_1	504472.Slin_5532	3.68e-23	93.6	COG4634@1|root,COG4634@2|Bacteria,4NYP1@976|Bacteroidetes,47WBN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_211837_2	1237149.C900_04828	2.22e-19	80.9	COG2442@1|root,COG2442@2|Bacteria,4NVK1@976|Bacteroidetes,47SGW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
k59_111289_1	1165841.SULAR_07108	3.97e-123	361.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
k59_157680_1	1255043.TVNIR_3085	2.42e-119	357.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1WVVJ@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_41712_2	395493.BegalDRAFT_2907	5.13e-85	261.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,46048@72273|Thiotrichales	72273|Thiotrichales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_149891_1	1168034.FH5T_05160	2.1e-92	296.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_219683_1	1441930.Z042_06045	1.37e-20	89.0	2E72W@1|root,331MG@2|Bacteria,1NAVS@1224|Proteobacteria,1SGAE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41717_1	1528106.JRJE01000009_gene1755	1.22e-166	479.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2JQ2W@204441|Rhodospirillales	204441|Rhodospirillales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_227236_2	700598.Niako_3870	1.06e-13	74.7	2EFSM@1|root,339IM@2|Bacteria,4NZ0M@976|Bacteroidetes,1IZWE@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4238
k59_134426_1	768671.ThimaDRAFT_2471	2.49e-43	152.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria,1X08U@135613|Chromatiales	135613|Chromatiales	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_134426_2	1085623.GNIT_1254	2.07e-58	189.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,467TG@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_34207_1	68194.JNXR01000021_gene806	2.43e-11	69.3	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_57043_1	1168034.FH5T_02905	2.21e-39	144.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,2FMQC@200643|Bacteroidia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_111295_1	1168034.FH5T_06485	4.87e-35	134.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NGJJ@976|Bacteroidetes,2FRXF@200643|Bacteroidia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149896_2	640513.Entas_3965	1.65e-05	51.6	COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria,3X3YT@547|Enterobacter	1236|Gammaproteobacteria	S	TIGRFAM Phage portal protein, HK97	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
k59_149899_1	387093.SUN_1363	6.24e-57	196.0	COG1752@1|root,COG1752@2|Bacteria,1NCAA@1224|Proteobacteria,430CE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_103473_1	1168034.FH5T_16910	6.86e-89	267.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,2FVWA@200643|Bacteroidia	976|Bacteroidetes	H	4Fe-4S single cluster domain	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_227572_1	1165841.SULAR_04567	2.15e-98	301.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,42PHS@68525|delta/epsilon subdivisions,2YQ45@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Paraquat-inducible protein B	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
k59_111705_1	1304885.AUEY01000011_gene1720	2.34e-09	65.1	COG2304@1|root,COG2304@2|Bacteria,1NDGA@1224|Proteobacteria,43DCN@68525|delta/epsilon subdivisions,2WRRD@28221|Deltaproteobacteria,2MME4@213118|Desulfobacterales	28221|Deltaproteobacteria	G	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_212228_2	1089551.KE386572_gene1869	7.25e-30	117.0	COG5530@1|root,COG5530@2|Bacteria,1RC90@1224|Proteobacteria,2VG7B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
k59_26502_1	1565314.OA34_09005	8.2e-22	93.6	COG0671@1|root,COG2453@1|root,COG0671@2|Bacteria,COG2453@2|Bacteria,1QSUD@1224|Proteobacteria,42TZH@68525|delta/epsilon subdivisions,2YPTC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IT	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc,PAP2_3
k59_26502_2	1565314.OA34_09000	2.1e-62	207.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2YMPA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_72852_1	1121405.dsmv_0346	1.07e-58	187.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MHNG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_72852_2	247490.KSU1_B0541	4.25e-19	82.8	COG1238@1|root,COG1238@2|Bacteria,2J05B@203682|Planctomycetes	203682|Planctomycetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_189008_1	1415779.JOMH01000001_gene3171	2.58e-57	180.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1X3ZK@135614|Xanthomonadales	135614|Xanthomonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_235544_1	755178.Cyan10605_1017	8.38e-82	256.0	COG3385@1|root,COG3385@2|Bacteria,1G27F@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_134820_1	1049564.TevJSym_ac00060	2.74e-107	316.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	abc transporter atp-binding protein	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_165960_1	387093.SUN_1196	8.63e-115	344.0	COG0665@1|root,COG0665@2|Bacteria,1QV9J@1224|Proteobacteria,42PP0@68525|delta/epsilon subdivisions,2YNBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_42006_1	402777.KB235903_gene774	1.48e-90	296.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
k59_80750_1	1227266.HMPREF1551_00356	3.04e-124	360.0	COG3039@1|root,COG3039@2|Bacteria,4NGY9@976|Bacteroidetes,1I0T1@117743|Flavobacteriia,1ESPR@1016|Capnocytophaga	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
k59_88393_1	388467.A19Y_3870	2.75e-38	147.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,NAD_binding_4,PP-binding,Thioesterase
k59_127215_1	631362.Thi970DRAFT_02285	7.78e-44	153.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria	1224|Proteobacteria	O	Peptidase M48	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_49664_1	395493.BegalDRAFT_0232	2e-57	190.0	COG4651@1|root,COG4651@2|Bacteria,1QUQS@1224|Proteobacteria,1T21E@1236|Gammaproteobacteria,461MK@72273|Thiotrichales	72273|Thiotrichales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_49664_2	1121374.KB891576_gene693	4.3e-11	63.5	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA	hda	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
k59_220075_1	1165841.SULAR_08242	5.01e-156	457.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_127223_1	1280706.AUJE01000004_gene2465	9.18e-26	110.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4H3A9@909932|Negativicutes	909932|Negativicutes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_165971_1	1168034.FH5T_19415	3e-40	149.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,2FQ61@200643|Bacteroidia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
k59_158079_1	1165841.SULAR_05933	3.22e-15	74.3	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2YMUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_158079_2	1165841.SULAR_05928	2.8e-69	218.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42QFD@68525|delta/epsilon subdivisions,2YND7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Ppx GppA	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_42024_2	1300345.LF41_2490	5.14e-08	52.0	2CD1J@1|root,301IK@2|Bacteria,1QD6I@1224|Proteobacteria,1T932@1236|Gammaproteobacteria,1XBM0@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103776_1	1168034.FH5T_12305	1.28e-31	120.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,2FNAX@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_212262_1	1265503.KB905160_gene2986	1.09e-38	139.0	2DNBN@1|root,32WN2@2|Bacteria,1N5BF@1224|Proteobacteria,1S7CH@1236|Gammaproteobacteria,2Q7BI@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
k59_34502_2	1269813.ATUL01000001_gene996	2.79e-61	200.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_243138_1	187272.Mlg_0516	2.21e-23	97.1	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1WWGF@135613|Chromatiales	135613|Chromatiales	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_243138_2	395493.BegalDRAFT_1351	3.85e-55	175.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,460YN@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
k59_204465_1	439235.Dalk_5089	7.71e-122	365.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_150257_1	1499967.BAYZ01000182_gene4433	9.22e-32	124.0	297CM@1|root,2ZUK5@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
k59_134853_1	344747.PM8797T_07799	9.4e-79	246.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_18566_2	2340.JV46_18360	4.63e-120	347.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1J54R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
k59_235569_1	313596.RB2501_14479	2.64e-83	250.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1I253@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49690_1	1265313.HRUBRA_01203	1.36e-83	252.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
k59_88416_1	2340.JV46_04250	1.77e-44	153.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,1JC06@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_88416_2	1121918.ARWE01000001_gene1721	1.26e-11	70.5	28JVP@1|root,2Z9KK@2|Bacteria,1R4DG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123662_1	697282.Mettu_3282	6.27e-111	332.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XEVC@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4478)	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
k59_193083_1	1168034.FH5T_20515	2.68e-45	157.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,2FVV3@200643|Bacteroidia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_61493_1	3880.AES58534	2.44e-16	78.6	COG2801@1|root,KOG0017@2759|Eukaryota,37TAQ@33090|Viridiplantae,3GDDG@35493|Streptophyta,4JUJN@91835|fabids	35493|Streptophyta	L	cytochrome c biogenesis	ccmFc	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	CcmF_C
k59_7476_1	1165841.SULAR_05888	4.55e-34	117.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,42WCY@68525|delta/epsilon subdivisions,2YSK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
k59_7476_2	1121288.AULL01000012_gene286	8.62e-23	88.6	2DNXG@1|root,32ZNF@2|Bacteria,4NV9Z@976|Bacteroidetes,1I563@117743|Flavobacteriia,3ZTY7@59732|Chryseobacterium	976|Bacteroidetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
k59_239525_1	159087.Daro_2223	2.96e-203	571.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,2VMP0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_22733_1	626887.J057_16740	7.81e-42	151.0	28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131289_1	1249627.D779_1731	5.09e-91	285.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,1X0A2@135613|Chromatiales	135613|Chromatiales	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_162061_1	395493.BegalDRAFT_2430	3.77e-228	650.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales	72273|Thiotrichales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_200985_1	396588.Tgr7_3022	1.55e-48	176.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_131292_1	1168034.FH5T_09990	1.33e-13	69.3	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,2FNEC@200643|Bacteroidia	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_131292_2	1168034.FH5T_09985	2.22e-67	205.0	COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes,2FSGK@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_247085_2	1168034.FH5T_18320	4.52e-48	166.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,2FNIY@200643|Bacteroidia	976|Bacteroidetes	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k59_23198_2	1408473.JHXO01000006_gene1236	2.76e-21	92.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FPEP@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
k59_15275_2	1123228.AUIH01000002_gene1522	5.72e-51	170.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1XH75@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_231853_1	652103.Rpdx1_3642	8.23e-41	150.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,2U7SC@28211|Alphaproteobacteria,3K57D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_84984_1	1313421.JHBV01000143_gene1146	7.83e-31	127.0	COG0433@1|root,COG0433@2|Bacteria,4NVJM@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
k59_231855_1	1250006.JHZZ01000001_gene2549	1.53e-30	121.0	2E3AK@1|root,32VD2@2|Bacteria,4NS79@976|Bacteroidetes,1I3S9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_92784_1	566466.NOR53_2790	2.92e-23	98.2	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J8WZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Sigma-54 interaction domain	cbrB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k59_216594_1	435908.IDSA_03440	1.96e-119	352.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,2QF4C@267893|Idiomarinaceae	1236|Gammaproteobacteria	K	RNA polymerase sigma	rpoS	GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_54155_1	760192.Halhy_4206	1.19e-36	141.0	COG2203@1|root,COG2972@1|root,COG2203@2|Bacteria,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_216595_1	1144312.PMI09_05605	8.72e-82	250.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
k59_231883_1	1122179.KB890459_gene985	8.16e-41	150.0	COG0642@1|root,COG2205@2|Bacteria,4NGAS@976|Bacteroidetes,1IUW2@117747|Sphingobacteriia	976|Bacteroidetes	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,TPR_8
k59_139214_2	87626.PTD2_18150	1.07e-11	67.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,2Q112@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG2925 Exonuclease I	sbcB	GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k59_15302_1	743719.PaelaDRAFT_4069	1.73e-05	54.7	COG0265@1|root,COG2010@1|root,COG4409@1|root,COG0265@2|Bacteria,COG2010@2|Bacteria,COG4409@2|Bacteria,1TQRX@1239|Firmicutes,4HEUW@91061|Bacilli	91061|Bacilli	G	An automated process has identified a potential problem with this gene model	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Laminin_G_3,Sialidase,YSIRK_signal
k59_216610_1	749222.Nitsa_1476	1.42e-50	169.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,42Q0J@68525|delta/epsilon subdivisions,2YPAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transport system, permease component	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k59_15305_1	313596.RB2501_08360	2.87e-63	212.0	COG1807@1|root,COG1807@2|Bacteria,4NEU7@976|Bacteroidetes,1HZQP@117743|Flavobacteriia	976|Bacteroidetes	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_108234_1	928724.SacglDRAFT_00579	3.65e-32	124.0	COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,4DZ49@85010|Pseudonocardiales	201174|Actinobacteria	L	Exodeoxyribonuclease III xth	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_216623_1	1165841.SULAR_05968	1.3e-90	275.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,43BHX@68525|delta/epsilon subdivisions,2YMEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_216635_1	1305836.AXVE01000003_gene2239	4.82e-23	103.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,26GI9@186818|Planococcaceae	91061|Bacilli	E	Fungalysin/Thermolysin Propeptide Motif	gelE	-	3.4.24.28,3.4.24.30	ko:K01400,ko:K08605	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
k59_154699_1	457398.HMPREF0326_03019	3.1e-45	164.0	COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,42UU6@68525|delta/epsilon subdivisions,2X85I@28221|Deltaproteobacteria,2MCJ2@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85057_1	762903.Pedsa_2239	7.66e-58	190.0	COG2267@1|root,COG2267@2|Bacteria,4NIGT@976|Bacteroidetes,1IUJU@117747|Sphingobacteriia	976|Bacteroidetes	I	COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily)	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hydrolase_4
k59_139233_1	926692.AZYG01000039_gene1662	2.19e-39	139.0	COG1752@1|root,COG1752@2|Bacteria,1UXU1@1239|Firmicutes,2598B@186801|Clostridia,3WB86@53433|Halanaerobiales	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_15341_1	313596.RB2501_11902	1.11e-53	177.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,1HYJ8@117743|Flavobacteriia	976|Bacteroidetes	K	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
k59_85068_1	1168034.FH5T_06685	1.07e-96	291.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,2FNVF@200643|Bacteroidia	976|Bacteroidetes	L	COG NOG11654 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
k59_108276_1	1179778.PMM47T1_13183	4.49e-85	263.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_139248_1	1165841.SULAR_04417	2.99e-75	241.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_139252_1	631362.Thi970DRAFT_02472	2.09e-86	263.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1WWID@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_139252_2	1207063.P24_02151	0.000676	44.3	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JQ4Z@204441|Rhodospirillales	204441|Rhodospirillales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K13896	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k59_15371_1	589865.DaAHT2_0933	9.06e-29	115.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2MJ1I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_108313_1	1038862.KB893805_gene4213	5.89e-19	91.7	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1
k59_85086_1	387093.SUN_0045	5.35e-24	99.0	COG3439@1|root,COG3439@2|Bacteria,1REDZ@1224|Proteobacteria,42T1V@68525|delta/epsilon subdivisions,2YPRR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_85086_2	90814.KL370892_gene2033	7.32e-16	77.4	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,46071@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_108315_1	1211114.ALIP01000101_gene1306	2.33e-15	70.1	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1X7EK@135614|Xanthomonadales	135614|Xanthomonadales	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_108315_2	1165841.SULAR_06833	1.22e-106	321.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_232008_1	1142394.PSMK_18670	1.69e-52	185.0	COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_15390_1	1168034.FH5T_21810	4.49e-28	109.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_15390_2	1168034.FH5T_21805	5.84e-95	288.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_232073_1	1168034.FH5T_21200	6.51e-69	215.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,2FSSJ@200643|Bacteroidia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k59_232092_1	573413.Spirs_2756	3.44e-22	99.8	COG0156@1|root,COG0156@2|Bacteria,2J7F0@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_232102_1	1168034.FH5T_11550	2.35e-73	228.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_232112_1	313596.RB2501_03535	2.7e-41	141.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_232112_2	1121875.KB907550_gene935	8.05e-103	309.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_46791_1	933262.AXAM01000010_gene1407	1.12e-78	246.0	COG1662@1|root,COG1662@2|Bacteria,1Q56I@1224|Proteobacteria,430ND@68525|delta/epsilon subdivisions,2WVQF@28221|Deltaproteobacteria,2MNPZ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IS1 transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_8177_1	395493.BegalDRAFT_1926	0.000761	43.9	COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,463G0@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_5
k59_8177_2	1255043.TVNIR_0227	2.28e-30	108.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales	135613|Chromatiales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_209277_1	1121459.AQXE01000004_gene1823	2.17e-37	140.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_170648_2	1046724.KB889877_gene1543	3.49e-49	164.0	COG0395@1|root,COG0395@2|Bacteria,1MVRG@1224|Proteobacteria,1RSNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type sugar transport system, permease component	ugpE	-	-	ko:K17323	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	BPD_transp_1
k59_39062_1	519989.ECTPHS_02129	4.16e-64	208.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales	135613|Chromatiales	GM	NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_46801_1	754476.Q7A_594	1.82e-53	178.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,4608R@72273|Thiotrichales	72273|Thiotrichales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_201554_1	472759.Nhal_1407	2.98e-14	76.6	COG0642@1|root,COG5001@1|root,COG2205@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WWRT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,EAL,GGDEF,HATPase_c,HisKA,Hpt,Response_reg
k59_240205_1	1165841.SULAR_06038	6.48e-84	265.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_70001_1	118005.AWNK01000008_gene492	5.15e-107	316.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
k59_70001_2	761193.Runsl_0008	1.38e-17	81.3	COG5464@1|root,COG5464@2|Bacteria,4NJT2@976|Bacteroidetes,47K3M@768503|Cytophagia	976|Bacteroidetes	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
k59_77742_1	768671.ThimaDRAFT_4355	5.63e-77	250.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,1SKFJ@1236|Gammaproteobacteria,1X099@135613|Chromatiales	135613|Chromatiales	L	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_240207_1	1392488.JHZY01000004_gene2361	2.33e-30	120.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,1I0SZ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_240207_2	641524.ADICYQ_5870	2.52e-29	115.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47M8T@768503|Cytophagia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_57184_1	717231.Flexsi_0602	5.48e-20	93.2	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_242920_1	713586.KB900536_gene1043	5.35e-41	140.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1WW37@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_242920_2	642227.HA49_09315	2.09e-10	65.1	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,4BUK9@82986|Tatumella	1236|Gammaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
k59_157873_1	406817.XNC1_2394	2.23e-15	71.2	COG3335@1|root,COG3335@2|Bacteria,1N1J6@1224|Proteobacteria,1S9ZQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_157873_2	395493.BegalDRAFT_1928	9.02e-131	398.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46039@72273|Thiotrichales	72273|Thiotrichales	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
k59_227366_1	1237149.C900_01919	1.04e-12	73.2	COG1028@1|root,COG2898@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2898@2|Bacteria,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,47XYI@768503|Cytophagia	976|Bacteroidetes	Q	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase,DUF2156,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_204270_1	1197477.IA57_11080	1.27e-18	91.7	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_142468_1	90813.JQMT01000001_gene170	2.66e-83	274.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4609J@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_242928_1	886377.Murru_0685	3.58e-121	376.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_72659_1	1165841.SULAR_00805	2.32e-72	217.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,42TUY@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
k59_72659_2	1165841.SULAR_00800	1.37e-125	369.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YTMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	COG4232 Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbD,Thioredoxin_2
k59_57192_1	999549.KI421514_gene304	2.11e-57	185.0	COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria,2829Z@191028|Leisingera	28211|Alphaproteobacteria	S	Alkylhydroperoxidase AhpD family core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_57192_2	1121104.AQXH01000002_gene569	1.41e-87	270.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,1IYDA@117747|Sphingobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_26314_1	34373.CCU80370	0.000617	48.5	2CNC5@1|root,2QV54@2759|Eukaryota,39S8X@33154|Opisthokonta,3NW2N@4751|Fungi,3QMXN@4890|Ascomycota,210WS@147548|Leotiomycetes	4751|Fungi	G	Pectate lyase superfamily protein	-	-	3.2.1.58	ko:K01210	ko00500,map00500	-	R00308,R03115	RC00467	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase_3
k59_235392_1	1386969.AWTB01000032_gene2216	2.29e-10	66.6	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4GB0Y@85026|Gordoniaceae	201174|Actinobacteria	Q	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_173296_2	1168034.FH5T_04330	9.49e-57	183.0	COG3022@1|root,COG3022@2|Bacteria,4NFP2@976|Bacteroidetes,2FNHM@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the UPF0246 family	yaaA	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_211951_1	102107.XP_008224000.1	0.0	1523.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta,4JREA@91835|fabids	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	ycf1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	-	-	-	-	-	-	-	-	-	Ycf1
k59_211951_2	59689.Al_scaffold_0009_187	5.67e-34	119.0	COG0184@1|root,KOG2815@2759|Eukaryota,37W6V@33090|Viridiplantae,3GKIP@35493|Streptophyta	35493|Streptophyta	J	30S ribosomal protein S15	rps15	GO:0000312,GO:0000313,GO:0000314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0009507,GO:0009532,GO:0009536,GO:0009547,GO:0009570,GO:0015935,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_211951_3	59689.scaffold_900034.1	3.15e-276	756.0	COG0649@1|root,KOG2870@2759|Eukaryota,37KKG@33090|Viridiplantae,3GDNP@35493|Streptophyta,3I15P@3699|Brassicales	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhH	GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0015979,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0019866,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0055035,GO:0055114,GO:0070469,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05572,ko:K05579	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_49kDa,NADHdh
k59_211951_4	4155.Migut.D01248.1.p	1.62e-102	310.0	COG0649@1|root,COG1005@1|root,KOG2870@2759|Eukaryota,KOG4770@2759|Eukaryota,383XN@33090|Viridiplantae,3GWT5@35493|Streptophyta,44QAB@71274|asterids	35493|Streptophyta	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K03878,ko:K05572	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_211951_5	4155.Migut.D01250.1.p	5.88e-102	296.0	COG1143@1|root,KOG3256@2759|Eukaryota,37YQF@33090|Viridiplantae,3GCUY@35493|Streptophyta,44RDM@71274|asterids	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhI	GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0055114	1.6.5.3	ko:K05580	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
k59_211951_6	4155.Migut.D01251.1.p	9.68e-108	312.0	COG0839@1|root,2QQHR@2759|Eukaryota,37N23@33090|Viridiplantae,3GCEY@35493|Streptophyta,44PRZ@71274|asterids	35493|Streptophyta	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	ndhG	GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0044237	1.6.5.3	ko:K05578	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q3
k59_211951_7	4155.Migut.D01252.1.p	5.47e-60	185.0	KOG4669@1|root,KOG4669@2759|Eukaryota,37V63@33090|Viridiplantae,3GJK7@35493|Streptophyta,44TJB@71274|asterids	35493|Streptophyta	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008137,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042180,GO:0042181,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050136,GO:0051186,GO:0051188,GO:0055035,GO:0055114,GO:0071704,GO:0098796,GO:1901576,GO:1901661,GO:1901663,GO:1902494	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
k59_211951_8	3075.A0A023HHU3	2.36e-36	124.0	COG1145@1|root,2S26M@2759|Eukaryota,37VAY@33090|Viridiplantae,34IB8@3041|Chlorophyta	3041|Chlorophyta	C	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn	psaC	-	-	ko:K02691	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Fer4
k59_211951_9	3827.XP_004516946.1	5.33e-299	827.0	COG1008@1|root,KOG4845@2759|Eukaryota,37QQT@33090|Viridiplantae,3G7MJ@35493|Streptophyta,4JSGR@91835|fabids	35493|Streptophyta	C	NAD(P)H-quinone oxidoreductase chain 4	ndhD	-	1.6.5.3	ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M
k59_211951_10	29760.VIT_00s0246g00170.t01	2.95e-166	473.0	COG0755@1|root,2QU0T@2759|Eukaryota,37NBU@33090|Viridiplantae,3GH1G@35493|Streptophyta	35493|Streptophyta	O	Cytochrome c biogenesis protein CcsA	ccsA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0008152,GO:0009536,GO:0015886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:1901678	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_211951_11	102107.XP_008223735.1	0.0	1065.0	COG1007@1|root,KOG4668@2759|Eukaryota,37P90@33090|Viridiplantae,3GBJ3@35493|Streptophyta,4JRH7@91835|fabids	35493|Streptophyta	C	A subunit of NADH dehydrogenase	ndhF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_80521_1	143224.JQMD01000002_gene2490	2.08e-25	109.0	COG0457@1|root,COG4977@1|root,COG5616@1|root,COG0457@2|Bacteria,COG4977@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
k59_72668_1	754476.Q7A_1045	2.12e-08	57.0	293CN@1|root,2Z9VJ@2|Bacteria,1MXNG@1224|Proteobacteria,1RZCQ@1236|Gammaproteobacteria,463I1@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_72668_2	1348657.M622_14765	3.65e-05	45.1	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,2VU50@28216|Betaproteobacteria,2KWXY@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_150009_1	502025.Hoch_1576	3.35e-39	139.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_173298_1	1123008.KB905706_gene883	2.09e-27	115.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
k59_119296_1	1121875.KB907547_gene3464	2.28e-76	238.0	29MQ2@1|root,308MT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_204288_1	768671.ThimaDRAFT_1762	3.31e-40	149.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,1RN9X@1236|Gammaproteobacteria,1X2V4@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2
k59_119299_1	1499683.CCFF01000014_gene4058	3.14e-33	130.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,36DFC@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_3309_1	96561.Dole_3250	7.51e-97	296.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_242948_1	156889.Mmc1_2505	1.29e-91	277.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2TTE2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
k59_3313_1	1165841.SULAR_03712	6.55e-50	169.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2YMKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_3313_2	1165841.SULAR_03717	5.35e-34	122.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,42RDD@68525|delta/epsilon subdivisions,2YSXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k59_111451_1	658187.LDG_6461	1.05e-66	226.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1JD02@118969|Legionellales	118969|Legionellales	M	Penicillin-binding protein OB-like domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_49505_1	395493.BegalDRAFT_2059	3.91e-50	180.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,45ZWK@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_65012_1	1129374.AJE_09419	1.78e-23	93.2	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,46851@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_65012_2	573370.DMR_p1_00220	9.16e-152	450.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,42NX3@68525|delta/epsilon subdivisions,2WME4@28221|Deltaproteobacteria,2M98A@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_26334_1	395493.BegalDRAFT_0207	1.18e-78	261.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T4BF@1236|Gammaproteobacteria	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	chiS	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg,Y_Y_Y
k59_96001_2	319224.Sputcn32_2432	3.9e-31	123.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,1SYM5@1236|Gammaproteobacteria,2Q8MR@267890|Shewanellaceae	1236|Gammaproteobacteria	C	fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
k59_127076_1	998674.ATTE01000001_gene1044	5.24e-60	187.0	COG4190@1|root,COG4190@2|Bacteria,1RDM2@1224|Proteobacteria,1SA4D@1236|Gammaproteobacteria,463CP@72273|Thiotrichales	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_127076_2	998674.ATTE01000001_gene1043	2.6e-58	182.0	COG5652@1|root,COG5652@2|Bacteria,1RDK4@1224|Proteobacteria,1SA6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135069_1	1165841.SULAR_09059	8.05e-125	365.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_135071_2	883.DvMF_1860	2.92e-51	180.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2M85Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_150407_1	261292.Nit79A3_1075	1.31e-123	369.0	COG3385@1|root,COG3385@2|Bacteria,1R807@1224|Proteobacteria,2W0D8@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_34689_1	153721.MYP_485	1.93e-62	223.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k59_96412_1	395961.Cyan7425_0791	1.38e-38	149.0	COG0515@1|root,COG0642@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,3KHHW@43988|Cyanothece	1117|Cyanobacteria	T	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_119724_1	1168034.FH5T_02790	3.74e-122	353.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,2FP6C@200643|Bacteroidia	976|Bacteroidetes	E	Shikimate	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
k59_173745_1	331113.SNE_A18650	1.4e-72	229.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2JG90@204428|Chlamydiae	204428|Chlamydiae	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_33
k59_220316_1	1123508.JH636440_gene2322	2.47e-86	269.0	COG0402@1|root,COG0402@2|Bacteria,2J1ZA@203682|Planctomycetes	203682|Planctomycetes	F	MGS-like domain	-	-	-	-	-	-	-	-	-	-	-	-	MGS
k59_119726_1	767029.HMPREF9154_2663	3.48e-15	80.1	COG1067@1|root,COG1067@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	-	-	3.4.21.53	ko:K04076,ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_16,Lon_C
k59_88607_1	3659.XP_004151701.1	1.68e-21	94.0	COG1970@1|root,2S7M9@2759|Eukaryota	2759|Eukaryota	M	Mortierella verticillata NRRL 6337	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL,zf-BED
k59_142973_1	1192034.CAP_4580	6.26e-07	53.9	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1MX27@1224|Proteobacteria	1224|Proteobacteria	TV	ABC-type multidrug transport system ATPase component	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
k59_49883_1	998674.ATTE01000001_gene1821	1.01e-71	219.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,460IN@72273|Thiotrichales	72273|Thiotrichales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_96431_1	1168034.FH5T_09240	1.95e-99	302.0	COG1262@1|root,COG3005@1|root,COG1262@2|Bacteria,COG3005@2|Bacteria,4NEUZ@976|Bacteroidetes,2FQ5J@200643|Bacteroidia	976|Bacteroidetes	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
k59_212482_1	1120965.AUBV01000003_gene408	9.6e-118	369.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1
k59_96434_1	1165841.SULAR_09414	2.6e-129	382.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2YM9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_212484_1	247634.GPB2148_2198	8.6e-93	284.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1J4Z9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_142975_1	765911.Thivi_2592	4.16e-162	464.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1WW2C@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_227842_1	1268072.PSAB_12030	1.82e-91	281.0	COG0008@1|root,COG0008@2|Bacteria,1TVW7@1239|Firmicutes,4HEN5@91061|Bacilli,26SH7@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_227842_2	1150469.RSPPHO_02924	2.69e-36	136.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2TTSC@28211|Alphaproteobacteria,2JQZJ@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional accessory protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_18774_1	1121937.AUHJ01000008_gene2037	5.93e-87	267.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,465CG@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_150422_1	1168034.FH5T_15315	1.29e-84	268.0	COG2866@1|root,COG2866@2|Bacteria,4NHBS@976|Bacteroidetes	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_37565_1	1121296.JONJ01000004_gene1007	0.000109	44.7	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,21Z1B@1506553|Lachnoclostridium	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_200021_1	1267535.KB906767_gene4444	1.03e-09	61.6	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_146158_1	1168034.FH5T_11885	2.93e-80	258.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,2FM0U@200643|Bacteroidia	976|Bacteroidetes	M	Penicillin-binding protein, transpeptidase domain protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_146159_1	749222.Nitsa_1024	4.09e-13	70.1	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_146159_2	1165841.SULAR_01215	6.22e-15	74.3	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions,2YR4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_114673_1	1112217.PPL19_23227	3.8e-69	235.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_137719_1	550540.Fbal_2545	1.35e-76	236.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exodeoxyribonuclease III	xthA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_246126_1	1168034.FH5T_16285	1.46e-10	62.8	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,SLH,SprB,VCBS
k59_246126_2	1267211.KI669560_gene634	7.27e-10	59.3	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1IS2R@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
k59_60500_1	1116472.MGMO_93c00040	5.07e-12	71.6	COG2351@1|root,COG3409@1|root,COG2351@2|Bacteria,COG3409@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria,1XG68@135618|Methylococcales	135618|Methylococcales	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_153265_2	1437882.AZRU01000002_gene2345	4.44e-35	125.0	2CDSP@1|root,32RYD@2|Bacteria,1N213@1224|Proteobacteria,1S7BM@1236|Gammaproteobacteria,1YJJU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169260_1	1346330.M472_18100	2.72e-12	68.9	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1IRZ6@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_215225_1	425104.Ssed_2865	3.1e-20	94.7	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QACP@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_161093_1	926550.CLDAP_40030	3.93e-59	204.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_68365_1	1121875.KB907546_gene2237	2.16e-56	181.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1HZJ2@117743|Flavobacteriia	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_68365_2	1121875.KB907546_gene2236	4.17e-10	60.1	2C2AI@1|root,32RA3@2|Bacteria,4NQ4M@976|Bacteroidetes,1I2Q3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184459_1	1168034.FH5T_14050	6.13e-95	290.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,2FMEZ@200643|Bacteroidia	976|Bacteroidetes	S	gliding motility-associated protein GldE	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_169263_1	1115515.EV102420_07_01380	4.91e-24	102.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,3XNMZ@561|Escherichia	1236|Gammaproteobacteria	P	potassium ion transport	yfbS	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_169263_2	28229.ND2E_2093	6.47e-22	92.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,2Q8F8@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_230542_1	1114964.L485_10185	6.99e-10	62.0	COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,2TREE@28211|Alphaproteobacteria,2JZZE@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
k59_223114_2	2340.JV46_10700	5.77e-32	116.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,1J616@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
k59_200039_1	331869.BAL199_13368	1.25e-06	50.8	COG2314@1|root,COG2314@2|Bacteria,1N8Y8@1224|Proteobacteria,2UFKT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
k59_52682_1	3750.XP_008351905.1	6.64e-13	70.9	COG2801@1|root,KOG0017@2759|Eukaryota,382BQ@33090|Viridiplantae	33090|Viridiplantae	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k59_137739_1	1453505.JASY01000001_gene3270	2.61e-10	60.5	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2NSCX@237|Flavobacterium	976|Bacteroidetes	GM	dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_29722_1	1479237.JMLY01000001_gene2011	7.12e-133	394.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,4659U@72275|Alteromonadaceae	1236|Gammaproteobacteria	CI	COG5016 Pyruvate oxaloacetate carboxyltransferase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_13959_1	1341181.FLJC2902T_17060	1.97e-21	96.3	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia,2NTJM@237|Flavobacterium	976|Bacteroidetes	S	peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_83620_1	78346.BRUM_0185	1.05e-14	79.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CZCW@85004|Bifidobacteriales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_223121_2	760154.Sulba_1194	2.62e-14	71.2	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,42S7K@68525|delta/epsilon subdivisions,2YPB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dtw domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DTW
k59_192153_1	1297742.A176_01374	3.21e-11	63.5	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2YZI7@29|Myxococcales	28221|Deltaproteobacteria	IQ	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k59_200431_1	1265507.KB899637_gene506	5.18e-50	181.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1Y4J1@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_192553_1	1165841.SULAR_06858	3.6e-143	410.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,TPR_8,VWA_2
k59_192553_2	1165841.SULAR_06863	2.46e-39	138.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP1P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_107154_1	398720.MED217_07071	2.42e-82	256.0	COG0701@1|root,COG0701@2|Bacteria,4NI2E@976|Bacteroidetes,1HX5I@117743|Flavobacteriia,2XK1M@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_6833_1	693986.MOC_3768	1.89e-76	246.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,1JR3K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_215597_1	395493.BegalDRAFT_3501	1.36e-74	250.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9
k59_91715_1	1343739.PAP_08585	8.12e-29	112.0	COG4902@1|root,arCOG03957@2157|Archaea,2XX05@28890|Euryarchaeota,243QP@183968|Thermococci	183968|Thermococci	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
k59_238962_1	1165841.SULAR_10059	5.19e-47	159.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42NNF@68525|delta/epsilon subdivisions,2YMDJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_123094_1	118173.KB235910_gene4512	4.45e-18	83.2	COG3497@1|root,COG3497@2|Bacteria,1G41S@1117|Cyanobacteria,1H9RA@1150|Oscillatoriales	1117|Cyanobacteria	S	Phage tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_123094_2	1168034.FH5T_17450	1.76e-37	135.0	2C8RB@1|root,32RMP@2|Bacteria,4NTVV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76527_1	83406.HDN1F_16400	7.28e-24	102.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,1J6ZA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
k59_60939_1	1236514.BAKL01000038_gene3084	1.16e-44	158.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia,4AKYN@815|Bacteroidaceae	976|Bacteroidetes	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_184830_1	1165841.SULAR_00690	1.94e-104	329.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_107164_1	1397528.Q671_03275	4.4e-42	152.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XHB6@135619|Oceanospirillales	135619|Oceanospirillales	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
k59_107164_2	316057.RPD_0190	0.000142	47.4	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,3JT7J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_45416_1	1232410.KI421422_gene2049	4.38e-189	536.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,43S0H@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_53121_1	1121875.KB907546_gene2199	3.79e-79	253.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_184832_1	1165841.SULAR_07540	1.41e-114	330.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,42RFD@68525|delta/epsilon subdivisions,2YP9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_45418_1	1121405.dsmv_3709	1.54e-55	182.0	COG0535@1|root,COG0535@2|Bacteria,1R4SH@1224|Proteobacteria,42NZR@68525|delta/epsilon subdivisions,2WKQA@28221|Deltaproteobacteria,2MHSP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k59_45418_2	933262.AXAM01000008_gene1945	7.69e-59	186.0	COG0664@1|root,COG0664@2|Bacteria,1QHKB@1224|Proteobacteria,42RR8@68525|delta/epsilon subdivisions,2WN8W@28221|Deltaproteobacteria,2MJUH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_37977_2	1177181.T9A_01149	7.71e-46	165.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1XI15@135619|Oceanospirillales	135619|Oceanospirillales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_91721_1	32057.KB217478_gene6530	1.33e-16	85.1	COG0515@1|root,COG5635@1|root,COG0515@2|Bacteria,COG5635@2|Bacteria,1G0B6@1117|Cyanobacteria,1HKBS@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	pknD	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_68753_1	743720.Psefu_3383	8.93e-28	117.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,1YVZD@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_246535_1	2340.JV46_16250	1.43e-56	196.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1J5FN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_45425_1	1226994.AMZB01000124_gene2974	1.56e-24	99.8	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1YG59@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	gag-polyprotein putative aspartyl protease	orf	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
k59_200458_1	1122207.MUS1_01340	1.22e-34	126.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,1S32X@1236|Gammaproteobacteria,1XJ8I@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
k59_200458_2	323261.Noc_0588	1.54e-26	104.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria,1X0PI@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_215616_2	1123236.KB899383_gene2694	9.75e-35	137.0	COG3405@1|root,COG3405@2|Bacteria,1MW17@1224|Proteobacteria,1RNEU@1236|Gammaproteobacteria,46CUC@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 8	bcsZ	-	3.2.1.4	ko:K01179,ko:K20542	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH8,GH9	-	Glyco_hydro_8
k59_674_1	65393.PCC7424_2981	3.48e-20	95.5	COG3568@1|root,COG3568@2|Bacteria,1G09C@1117|Cyanobacteria,3KJ78@43988|Cyanothece	1117|Cyanobacteria	S	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_93602_1	713586.KB900536_gene2104	6.3e-26	100.0	COG2920@1|root,COG2920@2|Bacteria,1N6BZ@1224|Proteobacteria,1S8YA@1236|Gammaproteobacteria,1WYWH@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_93602_2	1238186.AOCN01000010_gene1528	1.45e-12	67.8	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4FQIE@85023|Microbacteriaceae	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_108970_1	369723.Strop_0360	1.32e-38	146.0	COG2374@1|root,COG2374@2|Bacteria,2HTX5@201174|Actinobacteria,4D99T@85008|Micromonosporales	201174|Actinobacteria	S	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
k59_108970_2	378806.STAUR_2846	3.46e-34	125.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,430UE@68525|delta/epsilon subdivisions,2WW3W@28221|Deltaproteobacteria,2YV1I@29|Myxococcales	28221|Deltaproteobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
k59_132160_1	870187.Thini_0804	8.07e-61	187.0	COG0633@1|root,COG0633@2|Bacteria,1MZW3@1224|Proteobacteria,1SAM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_132160_2	870187.Thini_0805	3.08e-62	192.0	COG0633@1|root,COG0633@2|Bacteria,1N22M@1224|Proteobacteria,1S5ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_186353_2	395493.BegalDRAFT_2146	6.55e-50	169.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,460TP@72273|Thiotrichales	72273|Thiotrichales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k59_85806_1	102125.Xen7305DRAFT_00020060	2.93e-13	74.7	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
k59_116801_1	1168034.FH5T_16650	2.25e-14	70.9	COG1051@1|root,COG1051@2|Bacteria,4NIBP@976|Bacteroidetes,2FNT4@200643|Bacteroidia	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_116801_2	1408473.JHXO01000005_gene1492	9.01e-51	166.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,2FP0F@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_116809_1	765913.ThidrDRAFT_2175	9.17e-61	206.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WW39@135613|Chromatiales	135613|Chromatiales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_240449_1	1056820.KB900657_gene4173	4.45e-37	141.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,2PMGK@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	MviN-like protein	murJ	GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	iECO103_1326.ECO103_1114	MVIN
k59_124389_1	582899.Hden_0696	4.9e-68	209.0	COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,2UAPN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glycine cleavage H-protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_78034_1	439235.Dalk_5087	3.37e-119	352.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_8441_1	1168034.FH5T_07730	1.55e-91	292.0	COG0745@1|root,COG1879@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1879@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FWSR@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Peripla_BP_4,Reg_prop,Response_reg,Y_Y_Y
k59_194046_1	616991.JPOO01000001_gene3623	5.28e-85	277.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,23GQQ@178469|Arenibacter	976|Bacteroidetes	G	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
k59_16097_1	2340.JV46_29190	4.35e-95	295.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_178716_1	1116472.MGMO_12c00020	2.96e-137	402.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1XDQT@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_695_1	1168034.FH5T_08245	2.4e-30	115.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes,2G14T@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_695_2	1168034.FH5T_15220	6.11e-49	167.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,2FP2A@200643|Bacteroidia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
k59_39410_1	1165841.SULAR_00135	1.73e-119	362.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_240456_1	272560.BPSS1103	2.91e-37	141.0	COG1653@1|root,COG1653@2|Bacteria,1P3FA@1224|Proteobacteria,2WE2K@28216|Betaproteobacteria,1KBH0@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Mannan-binding protein	-	-	2.5.1.2	ko:K10811	ko00730,map00730	-	R02863	RC00224,RC00795	ko00000,ko00001,ko01000	-	-	-	MVL
k59_201809_1	63737.Npun_F3778	2.11e-93	308.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase
k59_85828_1	387093.SUN_1510	5.6e-71	231.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_240458_1	1117108.PAALTS15_12122	6.01e-56	198.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K15667	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_140069_1	309798.COPRO5265_1132	3.08e-41	145.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,42F5R@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_140069_2	1342299.Z947_708	1.85e-10	62.8	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,3ZV72@60136|Sulfitobacter	28211|Alphaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_16103_1	1416760.AYMS01000051_gene190	1.08e-68	221.0	COG3547@1|root,COG3547@2|Bacteria,4NIKY@976|Bacteroidetes,1HZCU@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_163173_1	1121405.dsmv_2856	8.73e-118	357.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_47147_1	187272.Mlg_2834	2.2e-114	331.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1WX9I@135613|Chromatiales	135613|Chromatiales	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_31749_1	1101190.ARWB01000001_gene744	3.48e-83	257.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2TRA6@28211|Alphaproteobacteria,370BJ@31993|Methylocystaceae	28211|Alphaproteobacteria	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_140070_1	765913.ThidrDRAFT_4330	5.51e-63	218.0	COG0823@1|root,COG1572@1|root,COG4870@1|root,COG0823@2|Bacteria,COG1572@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,LRR_5,Peptidase_C1,SLH
k59_240460_1	1168034.FH5T_12315	4.14e-121	365.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
k59_116825_1	1165841.SULAR_05718	5.96e-78	236.0	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_8455_1	3983.cassava4.1_004580m	1.44e-75	246.0	COG0807@1|root,KOG1284@2759|Eukaryota,37KWS@33090|Viridiplantae,3GB0Y@35493|Streptophyta,4JGCD@91835|fabids	35493|Streptophyta	H	riboflavin biosynthesis protein	-	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_93619_1	1121875.KB907546_gene2453	1.35e-54	192.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
k59_116826_1	998674.ATTE01000001_gene2040	5.44e-56	188.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,1S6C7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Esterase PHB depolymerase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
k59_23880_1	313596.RB2501_10035	3.08e-69	211.0	2AHD2@1|root,317Q0@2|Bacteria,4NQE4@976|Bacteroidetes,1I319@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_217400_1	2340.JV46_12120	1.71e-108	324.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1J4E0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_23882_1	395493.BegalDRAFT_1435	4.1e-82	259.0	COG2114@1|root,COG2199@1|root,COG2114@2|Bacteria,COG3706@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	cyaB	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,MASE2
k59_155478_1	1121870.AUAA01000035_gene121	1.31e-59	195.0	COG1294@1|root,COG1294@2|Bacteria,4NHZU@976|Bacteroidetes	976|Bacteroidetes	C	cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_201824_1	1168034.FH5T_15145	7.97e-63	210.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,2FRYR@200643|Bacteroidia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_225056_1	387093.SUN_1506	2.24e-51	177.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_225056_2	1165841.SULAR_04497	6.7e-40	136.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2YNXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP0618	ADK
k59_194072_1	1249627.D779_2025	4.14e-43	153.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1WWVU@135613|Chromatiales	135613|Chromatiales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_194072_2	1454004.AW11_01509	9.5e-38	133.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,1KQZZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_186382_1	1165841.SULAR_00565	2.31e-66	215.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42Z72@68525|delta/epsilon subdivisions,2YRGJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_170959_2	867900.Celly_1135	2.43e-18	85.1	COG2865@1|root,COG2865@2|Bacteria,4NEF5@976|Bacteroidetes,1HYUG@117743|Flavobacteriia,1F81H@104264|Cellulophaga	976|Bacteroidetes	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
k59_217409_1	1380380.JIAX01000012_gene390	8.29e-45	168.0	COG3505@1|root,COG3505@2|Bacteria,1MV1G@1224|Proteobacteria,2TR6N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Type IV secretory pathway VirD4	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
k59_31769_2	305900.GV64_21015	4.54e-123	357.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1XIYJ@135619|Oceanospirillales	135619|Oceanospirillales	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_108996_3	351348.Maqu_3772	2.3e-127	417.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_39429_1	1165841.SULAR_03657	8.61e-80	260.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_116844_1	429009.Adeg_0841	4.67e-26	107.0	COG1403@1|root,COG1403@2|Bacteria,1TPT3@1239|Firmicutes,249PQ@186801|Clostridia	186801|Clostridia	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,RRXRR
k59_217417_1	63737.Npun_F6505	3.28e-62	202.0	2A1HJ@1|root,30PR9@2|Bacteria,1G62Z@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of Unknown Function with PDB structure (DUF3865)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3865
k59_140088_1	290397.Adeh_4049	1.8e-19	92.4	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_23897_1	1121937.AUHJ01000036_gene2807	1.78e-120	353.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,4640P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_140091_1	1250278.JQNQ01000001_gene2429	1.22e-10	61.6	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
k59_731_1	1165841.SULAR_03757	2.64e-68	220.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_731_2	1033837.WANG_0966	4.48e-13	71.2	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,3F3PP@33958|Lactobacillaceae	91061|Bacilli	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_70297_1	1165841.SULAR_10424	1.97e-117	348.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_54967_1	1279038.KB907342_gene2626	1.38e-25	105.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,2JRR1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_85867_1	45596.XP_006690050.1	2.12e-19	88.6	COG0624@1|root,KOG2275@2759|Eukaryota,38BH3@33154|Opisthokonta,3NUCZ@4751|Fungi,3QJN0@4890|Ascomycota,3RTB4@4891|Saccharomycetes,47CGX@766764|Debaryomycetaceae	4751|Fungi	E	Peptidase dimerisation domain	-	GO:0003674,GO:0003824,GO:0006508,GO:0006518,GO:0006575,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009636,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0042219,GO:0042221,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0070011,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1990748	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_735_1	3880.AES99444	0.000338	41.2	2EPPS@1|root,2SSV1@2759|Eukaryota,380Z0@33090|Viridiplantae,3GQGG@35493|Streptophyta	3880.AES99444|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78082_1	1121013.P873_03605	5.23e-06	46.6	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1X41Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_60141_3	208439.AJAP_30130	3.6e-05	48.5	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
k59_168878_1	2340.JV46_04090	7.78e-56	191.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k59_214923_2	1123367.C666_07485	1.96e-41	142.0	COG3909@1|root,COG3909@2|Bacteria,1PT42@1224|Proteobacteria,2WADQ@28216|Betaproteobacteria,2KWK2@206389|Rhodocyclales	206389|Rhodocyclales	C	(sprot CYCP_CHRVI). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
k59_60148_1	1165841.SULAR_03118	3e-41	144.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2YR6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ecdysteroid kinase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_60148_2	1165841.SULAR_03123	1.78e-49	166.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,42RT7@68525|delta/epsilon subdivisions,2YRF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_238173_2	313596.RB2501_12352	4.86e-124	358.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_90986_1	522306.CAP2UW1_2536	2.2e-81	254.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KQBU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_90986_2	2340.JV46_05860	7.07e-50	166.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1J54F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	anr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_52379_1	7425.NV11546-PA	1.2e-05	48.1	COG4631@1|root,KOG0430@2759|Eukaryota,38GEI@33154|Opisthokonta,3BC8Q@33208|Metazoa,3CXMB@33213|Bilateria,41USP@6656|Arthropoda,3SGUI@50557|Insecta,46EKS@7399|Hymenoptera	33208|Metazoa	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	XDH	GO:0000166,GO:0000302,GO:0001932,GO:0001933,GO:0001934,GO:0001936,GO:0001937,GO:0002197,GO:0002237,GO:0003674,GO:0003824,GO:0004031,GO:0004854,GO:0004855,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005783,GO:0005829,GO:0006082,GO:0006091,GO:0006139,GO:0006144,GO:0006145,GO:0006150,GO:0006163,GO:0006195,GO:0006206,GO:0006520,GO:0006525,GO:0006568,GO:0006576,GO:0006586,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006805,GO:0006807,GO:0006810,GO:0006919,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007589,GO:0007595,GO:0008150,GO:0008152,GO:0008285,GO:0008340,GO:0009055,GO:0009056,GO:0009058,GO:0009064,GO:0009072,GO:0009112,GO:0009114,GO:0009115,GO:0009117,GO:0009166,GO:0009266,GO:0009308,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010044,GO:0010259,GO:0010468,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012505,GO:0016491,GO:0016528,GO:0016529,GO:0016623,GO:0016661,GO:0016662,GO:0016725,GO:0016726,GO:0016727,GO:0016903,GO:0017144,GO:0018130,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019752,GO:0022603,GO:0022900,GO:0023051,GO:0023056,GO:0023057,GO:0030151,GO:0030162,GO:0030856,GO:0030857,GO:0030879,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032268,GO:0032269,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032872,GO:0032874,GO:0032991,GO:0033993,GO:0034097,GO:0034404,GO:0034418,GO:0034465,GO:0034612,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042430,GO:0042493,GO:0042542,GO:0042579,GO:0042802,GO:0042803,GO:0042816,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043280,GO:0043281,GO:0043408,GO:0043410,GO:0043436,GO:0043473,GO:0043546,GO:0044093,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045471,GO:0045595,GO:0045596,GO:0045601,GO:0045602,GO:0045862,GO:0045936,GO:0045937,GO:0046100,GO:0046110,GO:0046113,GO:0046415,GO:0046434,GO:0046483,GO:0046486,GO:0046677,GO:0046700,GO:0046872,GO:0046903,GO:0046914,GO:0046983,GO:0048037,GO:0048066,GO:0048069,GO:0048072,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0050250,GO:0050421,GO:0050660,GO:0050662,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050878,GO:0050896,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051336,GO:0051345,GO:0051536,GO:0051537,GO:0051540,GO:0051704,GO:0051707,GO:0051716,GO:0051896,GO:0051898,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070302,GO:0070304,GO:0070555,GO:0070674,GO:0070887,GO:0071310,GO:0071345,GO:0071347,GO:0071356,GO:0071466,GO:0071704,GO:0071949,GO:0072521,GO:0072522,GO:0072523,GO:0072524,GO:0072527,GO:0080090,GO:0080134,GO:0080135,GO:0090287,GO:0090288,GO:0097159,GO:0097184,GO:0097305,GO:0098809,GO:1900744,GO:1900745,GO:1900746,GO:1900747,GO:1901265,GO:1901292,GO:1901342,GO:1901343,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901698,GO:1901700,GO:1902494,GO:1902531,GO:1902532,GO:1902533,GO:1902547,GO:1902548,GO:2000026,GO:2000116,GO:2000181,GO:2000377,GO:2000379,GO:2001056,GO:2001212,GO:2001213	1.17.1.4,1.17.3.2,1.2.3.1	ko:K00106,ko:K00157	ko00230,ko00232,ko00280,ko00350,ko00380,ko00750,ko00760,ko00830,ko00982,ko00983,ko01100,ko01110,ko01120,ko04146,ko04630,map00230,map00232,map00280,map00350,map00380,map00750,map00760,map00830,map00982,map00983,map01100,map01110,map01120,map04146,map04630	M00546	R01709,R01768,R01769,R02103,R02107,R02125,R02657,R03871,R04085,R04904,R07942,R07977,R07978,R07979,R08235,R08349,R08384,R08408	RC00075,RC00080,RC00143,RC00218,RC00242,RC01073,RC01074,RC02017,RC02199	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k59_52379_2	391937.NA2_17916	4.9e-28	105.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,43KDS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
k59_52379_3	883078.HMPREF9695_00104	7.02e-28	107.0	COG3832@1|root,COG3832@2|Bacteria,1RI3S@1224|Proteobacteria,2UB60@28211|Alphaproteobacteria,3JXJH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_21424_1	522306.CAP2UW1_3983	2.3e-56	188.0	COG4591@1|root,COG4591@2|Bacteria,1QVSQ@1224|Proteobacteria,2VMFB@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_98992_1	1122599.AUGR01000014_gene657	3.16e-57	188.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1S5U0@1236|Gammaproteobacteria,1XPB0@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_37213_1	948565.AFFP02000001_gene854	1.75e-49	161.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1Y8IF@135625|Pasteurellales	135625|Pasteurellales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_68099_1	143224.JQMD01000002_gene2083	5.23e-16	85.1	COG1511@1|root,COG2931@1|root,COG3210@1|root,COG5644@1|root,COG1511@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5644@2|Bacteria,4PKI0@976|Bacteroidetes,1HYWF@117743|Flavobacteriia	976|Bacteroidetes	U	PFAM Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
k59_122329_1	349520.PPE_01349	2.24e-21	95.1	COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,26R5N@186822|Paenibacillaceae	91061|Bacilli	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	odhA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_122329_2	335543.Sfum_3548	9.46e-16	77.4	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2MRUP@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_145873_1	1165841.SULAR_05808	6.97e-95	287.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_114328_1	1282356.H045_08265	3.26e-09	57.4	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1YSX9@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR2	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_114328_2	1209072.ALBT01000046_gene2555	2.66e-35	128.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1S7F5@1236|Gammaproteobacteria,1FH8G@10|Cellvibrio	1236|Gammaproteobacteria	NT	Two component signalling adaptor domain	cheW3	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_145876_1	392499.Swit_1374	4.14e-48	162.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria,2K42C@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_98998_1	903818.KI912269_gene470	8.21e-50	181.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448,ko:K02172	ko01501,ko01503,map01501,map01503	M00627,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1
k59_191813_1	870187.Thini_0482	8.65e-38	139.0	COG1100@1|root,COG1100@2|Bacteria,1R1W9@1224|Proteobacteria,1SK3H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
k59_191813_2	998674.ATTE01000001_gene589	3.43e-46	164.0	COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	50S ribosome-binding GTPase	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
k59_245815_1	713586.KB900536_gene1150	7.73e-34	127.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales	135613|Chromatiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_245815_2	443152.MDG893_13709	3.12e-16	70.5	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,4693X@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
k59_245815_3	2340.JV46_07160	2.13e-65	200.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1J67P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_245815_4	95619.PM1_0200745	2.67e-71	216.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_245815_5	2340.JV46_07140	2.07e-119	344.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1J4KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_245815_6	768066.HELO_1261	4.96e-101	303.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales	135619|Oceanospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_129990_1	1165841.SULAR_08829	1.84e-13	68.9	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,42NVN@68525|delta/epsilon subdivisions,2YMH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129990_3	1165841.SULAR_08839	1.17e-73	221.0	COG0735@1|root,COG0735@2|Bacteria,1NCW6@1224|Proteobacteria,42VHY@68525|delta/epsilon subdivisions,2YQK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_207144_2	329726.AM1_3688	1.21e-86	258.0	COG4675@1|root,COG4675@2|Bacteria,1G7MZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k59_207144_3	644076.SCH4B_3711	6.73e-57	179.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria,4NDIY@97050|Ruegeria	28211|Alphaproteobacteria	S	Phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k59_122334_1	1266909.AUAG01000063_gene1806	3.72e-108	324.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1WZPM@135613|Chromatiales	135613|Chromatiales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_199682_1	391612.CY0110_25486	9.7e-26	113.0	COG0642@1|root,COG2202@1|root,COG3899@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1GD97@1117|Cyanobacteria,3KHHW@43988|Cyanothece	1117|Cyanobacteria	T	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_9,Response_reg
k59_245821_1	562970.Btus_1013	6.5e-62	207.0	COG1078@1|root,COG1078@2|Bacteria	2|Bacteria	S	dGTPase activity	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_145879_1	1448139.AI20_09780	2.76e-50	173.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1Y3E6@135624|Aeromonadales	135624|Aeromonadales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k59_207153_1	1163617.SCD_n01433	7.01e-15	73.6	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_207153_2	983545.Glaag_4211	1.82e-12	68.6	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	ATPase with chaperone activity	comM	GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_222750_1	1120965.AUBV01000004_gene819	1.7e-16	84.0	COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes,47Y3I@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_130005_2	1165841.SULAR_09894	5.94e-103	301.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_83241_1	1168034.FH5T_14635	1.7e-64	206.0	COG1609@1|root,COG1609@2|Bacteria,4NKD4@976|Bacteroidetes,2FP0W@200643|Bacteroidia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
k59_222755_2	526222.Desal_2832	6.97e-26	106.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_160756_1	592027.CLG_B0569	4.96e-68	213.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24JC8@186801|Clostridia,36RET@31979|Clostridiaceae	186801|Clostridia	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214949_1	545694.TREPR_3511	2.19e-67	223.0	COG3604@1|root,COG3604@2|Bacteria,2J5TK@203691|Spirochaetes	203691|Spirochaetes	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k59_29338_1	349521.HCH_07028	9.26e-78	261.0	COG2373@1|root,COG3755@1|root,COG2373@2|Bacteria,COG3755@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,LprI,MG1
k59_122346_1	1208321.D104_08765	6.34e-29	110.0	COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria,1S2H9@1236|Gammaproteobacteria,1XJMX@135619|Oceanospirillales	135619|Oceanospirillales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_160760_1	485917.Phep_2695	3.07e-07	53.5	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IREG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
k59_37233_1	207954.MED92_02269	1.52e-55	181.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_37233_2	2340.JV46_27560	2.21e-19	81.6	COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	VV0993	-	-	-	-	-	-	-	-	-	-	-	-
k59_130007_1	445688.E3SNS2_9CAUD	7.03e-49	167.0	4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses  no RNA stage,4QPJE@28883|Caudovirales,4QI9Y@10662|Myoviridae	10662|Myoviridae	S	ATPase family associated with various cellular activities (AAA)	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_223348_2	865937.Gilli_3271	1.7e-32	120.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1I2BI@117743|Flavobacteriia	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146405_1	1134474.O59_004078	6.04e-47	164.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Type VI secretion	vasA	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k59_146405_2	377629.TERTU_1652	5.69e-41	139.0	COG3518@1|root,COG3518@2|Bacteria,1RG8W@1224|Proteobacteria,1S50E@1236|Gammaproteobacteria,2PP7S@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
k59_246403_1	765911.Thivi_2455	8e-22	99.4	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1WXVP@135613|Chromatiales	135613|Chromatiales	P	PFAM von Willebrand factor type A	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
k59_200254_1	376733.IT41_11225	3.65e-09	57.4	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,2PVKP@265|Paracoccus	28211|Alphaproteobacteria	G	C4-dicarboxylate ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_200254_2	864051.BurJ1DRAFT_4434	5.18e-66	207.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2VJXA@28216|Betaproteobacteria,1KK4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
k59_176643_1	2340.JV46_09790	6.09e-106	317.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1J50W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iSF_1195.SF3294	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_223351_1	1004785.AMBLS11_03095	5.66e-07	57.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,466HH@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_29939_1	1379701.JPJC01000258_gene2697	6.08e-16	84.7	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,2JZWN@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_29939_2	2340.JV46_26370	1.16e-06	49.7	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1J4CG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	iECO103_1326.ECO103_1114	MVIN
k59_52965_3	1380387.JADM01000014_gene4069	3.12e-06	49.7	COG0300@1|root,COG3320@1|root,COG0300@2|Bacteria,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1XMDW@135619|Oceanospirillales	135619|Oceanospirillales	M	dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
k59_45259_1	243090.RB6873	3.9e-36	135.0	COG3119@1|root,COG3119@2|Bacteria,2J2I9@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_45259_2	243090.RB2707	3.83e-18	84.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
k59_14153_1	395493.BegalDRAFT_0874	1.3e-93	281.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,460YZ@72273|Thiotrichales	72273|Thiotrichales	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_14153_2	1150398.JIBJ01000012_gene2154	1.71e-15	75.1	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,HTH_5,LMWPc
k59_177067_1	111780.Sta7437_2983	4.32e-05	47.4	28HH1@1|root,2Z7SS@2|Bacteria,1G3TR@1117|Cyanobacteria,3VMEX@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_177067_2	1123399.AQVE01000042_gene1324	1.04e-46	162.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_30408_1	1175654.A0A0S0N897_9CAUD	2.28e-65	218.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae	10699|Siphoviridae	S	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_84278_1	1291050.JAGE01000001_gene867	9.29e-50	178.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_76843_1	757424.Hsero_2164	2.06e-38	146.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,475YA@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	methyl-accepting chemotaxis	-	-	-	ko:K03406,ko:K03776,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,sCache_2
k59_115393_1	1479237.JMLY01000001_gene1390	2.76e-51	172.0	COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,1RRSG@1236|Gammaproteobacteria,469PD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Phenylacetic acid catabolic protein	paaC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_1526,iECO111_1330.ECO111_1784,iECSE_1348.ECSE_1475,iECW_1372.ECW_m1524,iEKO11_1354.EKO11_2423,iWFL_1372.ECW_m1524	PaaA_PaaC
k59_208182_2	1123399.AQVE01000010_gene3256	2.62e-51	170.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,4603P@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_69012_1	2340.JV46_15810	1.54e-93	286.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1J4RF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_30413_1	745310.G432_16050	6.71e-05	47.4	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K130@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
k59_30413_2	997884.HMPREF1068_02749	1.63e-30	122.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,2FNIM@200643|Bacteroidia,4AMAP@815|Bacteroidaceae	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_200689_1	1121875.KB907548_gene1319	2.72e-85	274.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
k59_231126_1	234267.Acid_7805	3.25e-17	77.4	COG2346@1|root,COG2346@2|Bacteria,3Y8WS@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_231126_2	366602.Caul_3842	2.08e-29	114.0	COG0583@1|root,COG0583@2|Bacteria,1R8PH@1224|Proteobacteria,2UEM8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_45708_1	1278307.KB906969_gene2215	2.71e-102	309.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_92005_1	888059.HMPREF9071_2432	2.8e-77	238.0	COG1662@1|root,COG3677@1|root,COG1662@2|Bacteria,COG3677@2|Bacteria,4NQ2X@976|Bacteroidetes,1I2SR@117743|Flavobacteriia,1ES1K@1016|Capnocytophaga	976|Bacteroidetes	L	Protein involved in DNA binding, transposase activity and transposition, DNA-mediated	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1,HTH_Tnp_IS1,Zn_Tnp_IS1
k59_138461_1	626887.J057_22745	1.22e-36	130.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,465RQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG0811 Biopolymer transport proteins	aglR	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_138461_2	864051.BurJ1DRAFT_1737	4.71e-20	86.7	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,2W2ZB@28216|Betaproteobacteria,1KNMZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_14647_1	349124.Hhal_2215	1.66e-07	50.8	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1WY2R@135613|Chromatiales	135613|Chromatiales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k59_14647_2	395493.BegalDRAFT_1945	1.58e-53	176.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,460DQ@72273|Thiotrichales	72273|Thiotrichales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_239276_1	378806.STAUR_4886	3.73e-65	210.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2X5I0@28221|Deltaproteobacteria,2YXYN@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_84281_2	445696.E3SST5_9CAUD	2.61e-35	146.0	4QIJU@10662|Myoviridae	10662|Myoviridae	S	virus tail assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_138472_1	1168034.FH5T_03215	9.16e-61	202.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,2FMMA@200643|Bacteroidia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_231133_1	1165841.SULAR_07660	2.66e-06	48.5	COG0745@1|root,COG0745@2|Bacteria,1QZNH@1224|Proteobacteria,42SJZ@68525|delta/epsilon subdivisions,2YPIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_231133_2	1165841.SULAR_07655	1.63e-57	194.0	COG0642@1|root,COG0642@2|Bacteria,1RGPU@1224|Proteobacteria,42RPY@68525|delta/epsilon subdivisions,2YPD9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_123399_1	706434.HMPREF9429_00841	1.31e-32	119.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,4H443@909932|Negativicutes	909932|Negativicutes	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_200701_1	395493.BegalDRAFT_2616	2.21e-19	80.5	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,461CG@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_200701_2	395493.BegalDRAFT_2615	7.34e-41	136.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,4613R@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_92022_1	1220535.IMCC14465_09170	2.3e-35	137.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_231135_1	1165841.SULAR_09944	4.46e-139	409.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_69029_1	1168034.FH5T_18350	2.28e-85	265.0	COG0438@1|root,COG0438@2|Bacteria,4P01C@976|Bacteroidetes	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_76862_1	95619.PM1_0208150	1.52e-13	72.4	COG2885@1|root,COG2885@2|Bacteria,1RENP@1224|Proteobacteria,1S4IW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	oprF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
k59_76862_2	880073.Calab_1666	1.96e-18	85.5	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	potE	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
k59_154000_1	1049564.TevJSym_ai00970	5.36e-16	78.6	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1J53A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475	ACT_4,HD_4,RelA_SpoT,TGS
k59_30426_1	1165841.SULAR_03317	1.8e-143	428.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_107480_1	314230.DSM3645_20627	6.11e-68	221.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_223825_1	335543.Sfum_1919	6.27e-43	161.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2MR6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_138479_2	765910.MARPU_08845	2.33e-28	107.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1WZ4Z@135613|Chromatiales	135613|Chromatiales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_192869_1	1123073.KB899241_gene2109	2.99e-07	57.8	COG1879@1|root,COG2374@1|root,COG1879@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,LTD
k59_131012_1	1121948.AUAC01000004_gene5	7.45e-51	174.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,43WUZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_131012_2	714943.Mucpa_2520	7.47e-59	196.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IP5K@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_115421_1	553385.JEMF01000074_gene1321	1.17e-33	124.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1XHC4@135619|Oceanospirillales	135619|Oceanospirillales	G	catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_115421_2	713587.THITH_15935	2.3e-36	135.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales	135613|Chromatiales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_208215_1	1442598.JABW01000031_gene1276	2.88e-16	79.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,42QR0@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_208215_2	1442598.JABW01000031_gene1279	9.47e-24	93.6	COG2963@1|root,COG2963@2|Bacteria,1QWYW@1224|Proteobacteria,432XW@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Protein of unknown function (DUF2805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2805
k59_53442_1	838561.P344_05775	1.62e-10	68.9	COG0515@1|root,COG0515@2|Bacteria,3WT4P@544448|Tenericutes	544448|Tenericutes	KLT	serine threonine protein kinase	pknB	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_192877_1	1165841.SULAR_00045	7.26e-30	119.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_76880_1	382464.ABSI01000002_gene4381	1.83e-102	327.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,46U8Z@74201|Verrucomicrobia,2ITGR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EI	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_185134_1	46234.ANA_C11024	1.08e-43	162.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HMC1@1161|Nostocales	1117|Cyanobacteria	Q	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_38756_2	1117319.PSPO_10764	1.19e-71	225.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,2Q148@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NU	Twitching motility protein PilT	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_185774_2	457421.CBFG_03968	2.21e-26	111.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,268NF@186813|unclassified Clostridiales	186801|Clostridia	E	Glutamate synthase central domain	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_139399_1	313606.M23134_04461	1.26e-71	224.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,47JB0@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_232178_1	406818.XBJ1_3700	8.8e-51	185.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,AAA_30,UvrD_C_2
k59_147044_1	1479237.JMLY01000001_gene1921	7.45e-74	236.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RV50@1236|Gammaproteobacteria,464N2@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_61999_1	1219080.VEZ01S_38_00230	1.1e-50	182.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1XUTH@135623|Vibrionales	135623|Vibrionales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_154827_1	445971.ANASTE_00818	2.94e-51	176.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,25UQG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
k59_31096_1	1121011.AUCB01000005_gene2314	6.1e-45	164.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia,23GFA@178469|Arenibacter	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_208987_1	765912.Thimo_2945	1.08e-176	508.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,1WWYA@135613|Chromatiales	135613|Chromatiales	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_201254_2	1453505.JASY01000010_gene4008	6.69e-07	54.7	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia,2NS9E@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_116117_1	237368.SCABRO_03996	2.98e-12	66.6	COG1012@1|root,COG1012@2|Bacteria,2IX0I@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_171444_1	472759.Nhal_2414	3.05e-79	249.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_210011_1	1165841.SULAR_04122	1.07e-62	193.0	COG2010@1|root,COG2010@2|Bacteria,1Q2E5@1224|Proteobacteria,42VHQ@68525|delta/epsilon subdivisions,2YQ7N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_210011_2	1165841.SULAR_04127	7.09e-75	230.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2YM9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_240909_1	2340.JV46_13970	1.83e-104	315.0	COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,1RQ44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_9055_1	1165841.SULAR_10674	2.89e-41	137.0	2DDD8@1|root,2ZHK8@2|Bacteria,1Q56G@1224|Proteobacteria,42V7B@68525|delta/epsilon subdivisions,2YQI8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_9055_2	1165841.SULAR_10679	8.42e-46	150.0	COG5501@1|root,COG5501@2|Bacteria	2|Bacteria	-	-	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
k59_32383_1	118005.AWNK01000005_gene1686	2.32e-129	383.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016866,GO:0016869,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0050368,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	4.3.1.23,4.3.1.24,4.3.1.3,5.4.3.6	ko:K01745,ko:K10774,ko:K10775,ko:K21181	ko00340,ko00350,ko00360,ko00940,ko01059,ko01100,ko01110,ko01130,map00340,map00350,map00360,map00940,map01059,map01100,map01110,map01130	M00039,M00045,M00137,M00350,M00827,M00828	R00697,R00737,R01168,R11366	RC00361,RC00366	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_171448_1	313596.RB2501_09705	2.8e-181	533.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_233428_1	1249997.JHZW01000003_gene3601	4.45e-16	76.6	28HM7@1|root,2Z7VU@2|Bacteria,4NGV1@976|Bacteroidetes,1HXYU@117743|Flavobacteriia,2PID4@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_233428_2	1492737.FEM08_33520	6.39e-18	82.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia,2NTHK@237|Flavobacterium	976|Bacteroidetes	O	Molecular chaperone, HSP90	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_32386_1	1165841.SULAR_01753	3.37e-11	59.3	2BQIT@1|root,32JEK@2|Bacteria,1Q29V@1224|Proteobacteria,42V8T@68525|delta/epsilon subdivisions,2YQEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_32386_2	1165841.SULAR_01758	2.42e-119	360.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_171450_1	1123228.AUIH01000131_gene2866	1.31e-135	404.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1XS1N@135619|Oceanospirillales	135619|Oceanospirillales	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_171450_2	1122211.JMLW01000022_gene2550	1.84e-09	55.5	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,1XM0E@135619|Oceanospirillales	135619|Oceanospirillales	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_155874_1	1165841.SULAR_09679	4.25e-200	572.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_32390_1	319236.JCM19294_335	3.48e-34	126.0	COG4783@1|root,COG4783@2|Bacteria,4NEF9@976|Bacteroidetes,1HZ36@117743|Flavobacteriia,3HM26@363408|Nonlabens	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_117304_1	748449.Halha_2425	4.44e-33	125.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,24EGS@186801|Clostridia,3WAIK@53433|Halanaerobiales	186801|Clostridia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_117304_2	1002804.HBZC1_12860	1.61e-09	58.5	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2YP5R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_101757_1	1408428.JNJP01000004_gene2881	1.41e-63	207.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
k59_101757_2	1035193.HMPREF9073_01061	3.36e-14	73.2	COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,4NGR1@976|Bacteroidetes,1HY3E@117743|Flavobacteriia,1ER8E@1016|Capnocytophaga	976|Bacteroidetes	G	Psort location Cytoplasmic, score 9.97	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
k59_117307_1	1430440.MGMSRv2_0014	1.61e-32	119.0	COG3415@1|root,COG3415@2|Bacteria,1NEVE@1224|Proteobacteria	1224|Proteobacteria	L	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_Tnp_IS630
k59_101763_1	930166.CD58_26705	8.51e-88	287.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_32396_1	1168034.FH5T_04800	3.96e-41	139.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,2FT42@200643|Bacteroidia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
k59_32396_2	1168034.FH5T_04805	8.06e-20	89.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_78570_1	1121377.KB906410_gene623	8.11e-37	133.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ybaJ	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_148101_1	1506583.JQJY01000004_gene3070	2.23e-42	150.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia,2NSUB@237|Flavobacterium	976|Bacteroidetes	E	Cystathionine beta-lyase	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_171460_1	395493.BegalDRAFT_3280	4.12e-31	119.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,45ZVI@72273|Thiotrichales	72273|Thiotrichales	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_225545_1	264730.PSPPH_0860	7.81e-30	118.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1Z5MS@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k59_155879_1	454957.IA64_16195	6.58e-44	167.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X4ZC@135614|Xanthomonadales	135614|Xanthomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_40002_1	1165841.SULAR_01698	3.65e-70	221.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_40002_3	1165841.SULAR_01708	6.16e-106	313.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_140510_1	1165841.SULAR_08242	2.4e-109	335.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_210025_1	63418.F2Q3T5	5.22e-53	181.0	COG0418@1|root,KOG2902@2759|Eukaryota,38HVG@33154|Opisthokonta,3NU7X@4751|Fungi,3QPB2@4890|Ascomycota,20AD8@147545|Eurotiomycetes,3AZX6@33183|Onygenales,3FS8J@34384|Arthrodermataceae	4751|Fungi	F	Amidohydrolase	URA4	GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019856,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YLR420W,iND750.YLR420W	Amidohydro_1,Amidohydro_2
k59_86317_1	1122603.ATVI01000005_gene3433	3.65e-41	156.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1X4ST@135614|Xanthomonadales	135614|Xanthomonadales	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_155883_1	1165841.SULAR_09839	3.14e-107	329.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_240934_1	1165841.SULAR_00905	1.32e-132	397.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_240934_2	598659.NAMH_1591	2.38e-15	75.5	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_140520_1	313596.RB2501_02040	7.03e-68	225.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
k59_63086_1	1165841.SULAR_10424	2.49e-94	287.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_132695_1	1265310.CCBD010000015_gene3700	4.6e-67	225.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GKFE@201174|Actinobacteria,233TJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	acoB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_9076_1	1165841.SULAR_09394	5.49e-39	140.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_9076_2	1165841.SULAR_09389	3.63e-77	246.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2YRID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13,SPOR
k59_233461_1	396588.Tgr7_0944	1.47e-160	459.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1WXTC@135613|Chromatiales	135613|Chromatiales	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_86333_1	1158292.JPOE01000002_gene1473	1.51e-05	51.6	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,1KIT6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_9082_1	713586.KB900536_gene1317	7.66e-83	255.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1WZYG@135613|Chromatiales	135613|Chromatiales	G	Fructose-bisphosphate aldolase class-I	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
k59_133121_1	1242864.D187_006788	9.48e-31	119.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2X5I0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_133121_2	215803.DB30_8910	9.28e-33	122.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2X5HZ@28221|Deltaproteobacteria,2YYH5@29|Myxococcales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_1737_1	243233.MCA1432	3.67e-53	180.0	COG0438@1|root,COG0438@2|Bacteria,1P8MT@1224|Proteobacteria,1S8IY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_218345_1	204773.HEAR2762	2.38e-35	125.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,4743E@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_218345_2	857087.Metme_1744	1.2e-84	262.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1XEJ4@135618|Methylococcales	135618|Methylococcales	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_187274_3	1168034.FH5T_11030	4.45e-60	186.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,2FTJ4@200643|Bacteroidia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
k59_226005_1	2340.JV46_06240	5.13e-89	268.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1J68C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Fructosamine kinase	yniA	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_233901_1	563040.Saut_1320	1.82e-18	82.0	COG0845@1|root,COG0845@2|Bacteria,1QE6S@1224|Proteobacteria,42QGG@68525|delta/epsilon subdivisions,2YNSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cmeE	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_233901_2	1165841.SULAR_04532	9.24e-78	255.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_140991_1	998674.ATTE01000001_gene424	6.12e-129	378.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,461TD@72273|Thiotrichales	72273|Thiotrichales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_164090_1	65393.PCC7424_3245	2.42e-48	174.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
k59_40463_1	1165841.SULAR_09704	1.32e-141	405.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_24862_1	313628.LNTAR_15142	2.08e-29	124.0	COG1205@1|root,COG1205@2|Bacteria	2|Bacteria	L	dead DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
k59_110000_1	1121373.KB903635_gene877	5.89e-42	153.0	COG1672@1|root,COG1672@2|Bacteria,4NSII@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,AAA_35
k59_1754_1	1242864.D187_009246	1.83e-12	75.9	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X83K@28221|Deltaproteobacteria,2YUDP@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_187286_1	387093.SUN_0825	1.02e-90	270.0	296U5@1|root,2ZU34@2|Bacteria,1Q4NP@1224|Proteobacteria,42ZIJ@68525|delta/epsilon subdivisions,2YRP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_233911_1	1005395.CSV86_13200	4.39e-16	77.4	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1YWGB@136845|Pseudomonas putida group	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_233911_2	243233.MCA1911	2.53e-104	331.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RS9N@1236|Gammaproteobacteria,1XG44@135618|Methylococcales	135618|Methylococcales	P	heavy metal translocating P-type ATPase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_226020_1	1165841.SULAR_03637	3.14e-87	265.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_229856_1	1122599.AUGR01000020_gene1538	2.79e-89	283.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1XI15@135619|Oceanospirillales	135619|Oceanospirillales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_59802_1	305700.B447_09123	4.24e-08	53.9	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,2KV91@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_59802_2	2340.JV46_03540	1.08e-81	249.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4IE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
k59_113930_1	1123236.KB899384_gene2377	3.27e-56	184.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,465KQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG1064 Zn-dependent alcohol dehydrogenases	yahK	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_113932_1	7029.ACYPI071932-PA	2.09e-18	90.1	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1758,DUF1759,Peptidase_A17,rve
k59_191416_2	545695.TREAZ_3501	8.93e-28	114.0	COG1947@1|root,COG1947@2|Bacteria,2J7N4@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_237821_1	1165841.SULAR_00080	4.87e-135	396.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_206770_1	1286106.MPL1_07348	1.09e-63	202.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,46069@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
k59_206770_2	561229.Dd1591_2375	5.99e-44	145.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,2JEID@204037|Dickeya	1236|Gammaproteobacteria	S	Belongs to the UPF0145 family	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
k59_206770_3	465515.Mlut_04610	9.75e-10	59.7	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,1W80X@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
k59_175750_1	631362.Thi970DRAFT_04114	1.64e-37	142.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,1RQ8X@1236|Gammaproteobacteria,1WW6F@135613|Chromatiales	135613|Chromatiales	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_137142_1	156889.Mmc1_0394	4.5e-28	119.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,2TRJE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	MA20_16190	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_5761_1	1408473.JHXO01000001_gene2385	5.38e-79	259.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia	976|Bacteroidetes	G	alpha-glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
k59_90666_1	395963.Bind_2820	3.16e-35	140.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2U0ZY@28211|Alphaproteobacteria,3NAVP@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_90666_2	489825.LYNGBM3L_07370	4.13e-09	57.4	COG0626@1|root,COG0626@2|Bacteria,1G43Q@1117|Cyanobacteria,1HHPF@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_175754_1	292415.Tbd_0872	1.83e-38	142.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria,1KS3F@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FAD binding domain	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k59_175754_2	1541065.JRFE01000016_gene535	8.37e-25	94.0	COG5450@1|root,COG5450@2|Bacteria,1GAQ0@1117|Cyanobacteria,3VNAY@52604|Pleurocapsales	1117|Cyanobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
k59_245486_1	345341.KUTG_08936	8.83e-85	270.0	COG1032@1|root,COG1032@2|Bacteria,2HGPR@201174|Actinobacteria,4E1SE@85010|Pseudonocardiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_222407_1	105559.Nwat_2745	1.08e-72	238.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1WW2F@135613|Chromatiales	135613|Chromatiales	P	Chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
k59_160377_1	1198452.Jab_2c00030	9.02e-52	187.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,473K1@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Linear gramicidin synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_13300_1	641147.HMPREF9021_00797	5.22e-105	308.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,2VKSI@28216|Betaproteobacteria,2KQ3J@206351|Neisseriales	206351|Neisseriales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_113949_1	1165841.SULAR_03452	1.81e-102	308.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_152605_1	272123.Anacy_1717	9.48e-62	211.0	COG0145@1|root,COG0145@2|Bacteria,1G02W@1117|Cyanobacteria,1HIH3@1161|Nostocales	1117|Cyanobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_52044_1	313595.P700755_001746	4.71e-45	162.0	COG4372@1|root,COG4372@2|Bacteria,4PM9B@976|Bacteroidetes,1HZDB@117743|Flavobacteriia	976|Bacteroidetes	S	Transposase C of IS166 homeodomain	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_21020_1	2340.JV46_18710	1.28e-37	128.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1J6QE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_106005_1	1197951.I6R0Z0_9CAUD	4.8e-32	123.0	4QGZN@10239|Viruses,4R0FF@35237|dsDNA viruses  no RNA stage,4QTUK@28883|Caudovirales	28883|Caudovirales	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_90673_2	1255043.TVNIR_2247	4.53e-57	189.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1WWRP@135613|Chromatiales	135613|Chromatiales	C	Isocitrate lyase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k59_129626_1	1168034.FH5T_05020	1.68e-72	242.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
k59_199344_1	876044.IMCC3088_2031	6.18e-47	166.0	COG2866@1|root,COG2866@2|Bacteria,1N6CX@1224|Proteobacteria,1RZAW@1236|Gammaproteobacteria,1J9GJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
k59_113972_1	3649.evm.model.supercontig_263.25	2.52e-72	218.0	COG0099@1|root,KOG3311@2759|Eukaryota,37VU7@33090|Viridiplantae,3GIU9@35493|Streptophyta	35493|Streptophyta	J	Ribosomal protein S13	rps13	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_44363_1	1165841.SULAR_05518	1.29e-89	280.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_67784_1	1286632.P278_08280	6.67e-45	160.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,1HYMG@117743|Flavobacteriia	976|Bacteroidetes	E	Glycine D-amino acid	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_21031_1	754477.Q7C_1315	8.65e-30	116.0	COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,463VW@72273|Thiotrichales	72273|Thiotrichales	S	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_21031_2	1266909.AUAG01000010_gene2668	5.05e-20	89.4	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_129630_1	2340.JV46_16490	1.63e-154	437.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J69M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_113978_1	349521.HCH_01801	1e-59	196.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XHGU@135619|Oceanospirillales	135619|Oceanospirillales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_13312_1	398580.Dshi_1541	8.75e-23	97.1	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_137652_6	194699.Q774Z7_BPBPP	2.12e-23	92.0	4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses  no RNA stage,4QPH6@28883|Caudovirales,4QNEM@10744|Podoviridae	10744|Podoviridae	S	Protein of unknwon function (DUF3310)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160990_2	867900.Celly_0996	1.46e-11	65.9	COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160997_1	717774.Marme_0865	2.48e-30	126.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1XMIT@135619|Oceanospirillales	135619|Oceanospirillales	M	Salmonella virulence plasmid 65kDa B protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB
k59_153192_2	2340.JV46_27400	4.85e-49	157.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S6HX@1236|Gammaproteobacteria,1JBUQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pnaB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
k59_153192_3	1049564.TevJSym_bl00090	1.42e-43	154.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1J5AS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_230464_1	909663.KI867150_gene2465	2.9e-122	375.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,42PRE@68525|delta/epsilon subdivisions,2WJRD@28221|Deltaproteobacteria,2MRGT@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_184375_1	1005048.CFU_3401	2.15e-06	55.1	COG1629@1|root,COG4771@2|Bacteria,1QURZ@1224|Proteobacteria,2VS53@28216|Betaproteobacteria,476RM@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_29622_1	234267.Acid_3964	1.62e-38	148.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y7IX@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HAMP,Pkinase
k59_114590_1	1121937.AUHJ01000005_gene2298	5.22e-76	254.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_207378_1	313596.RB2501_08405	4.85e-73	224.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_230472_2	1165841.SULAR_01315	3.81e-98	292.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2YMHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_68329_1	1384066.JAGT01000001_gene158	5.17e-21	104.0	COG5184@1|root,COG5184@2|Bacteria,1TS5I@1239|Firmicutes,24A8Z@186801|Clostridia,3WRHH@541000|Ruminococcaceae	186801|Clostridia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2,SLH
k59_114595_1	485913.Krac_4417	1.78e-49	170.0	COG2159@1|root,COG2159@2|Bacteria,2G8UX@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
k59_6412_1	1165841.SULAR_06798	1.72e-64	206.0	COG0618@1|root,COG0618@2|Bacteria,1RAUQ@1224|Proteobacteria,42RKG@68525|delta/epsilon subdivisions,2YNXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_6412_2	1165841.SULAR_06793	4.16e-13	68.9	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_83506_1	1255043.TVNIR_3819	3.11e-101	314.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1WW1J@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_60440_1	1121937.AUHJ01000001_gene488	1.32e-103	306.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,464FD@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_223046_1	1165841.SULAR_00295	1.79e-117	346.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_230482_1	1168034.FH5T_14145	2.3e-96	288.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,2FN4I@200643|Bacteroidia	976|Bacteroidetes	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
k59_184396_1	1165841.SULAR_01085	1.05e-44	159.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_215169_1	1116472.MGMO_94c00120	6.44e-171	518.0	COG1215@1|root,COG1216@1|root,COG2227@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria,1XDIU@135618|Methylococcales	135618|Methylococcales	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
k59_63745_1	105559.Nwat_1203	5.86e-92	283.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,1RS93@1236|Gammaproteobacteria,1X0KC@135613|Chromatiales	135613|Chromatiales	I	Squalene phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
k59_63745_2	1123257.AUFV01000002_gene2530	1.54e-25	99.4	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1X709@135614|Xanthomonadales	135614|Xanthomonadales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_9735_1	246197.MXAN_5941	6.76e-28	107.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
k59_9735_2	105559.Nwat_1726	3.85e-20	87.4	COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,1WXZX@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_125712_1	1123508.JH636467_gene6897	5.73e-39	141.0	COG3385@1|root,COG3385@2|Bacteria,2J4PY@203682|Planctomycetes	203682|Planctomycetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_187506_2	1049564.TevJSym_al00690	1.57e-08	57.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1J7D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	narX	GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	2.7.13.3	ko:K07673,ko:K07674	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
k59_203015_1	880072.Desac_0257	5.76e-83	264.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42RS1@68525|delta/epsilon subdivisions,2WNR1@28221|Deltaproteobacteria,2MQVG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_17263_1	395493.BegalDRAFT_3092	4.78e-20	89.4	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,460A8@72273|Thiotrichales	72273|Thiotrichales	NU	Secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_210682_1	243090.RB11084	2.52e-75	251.0	COG0457@1|root,COG0795@1|root,COG0457@2|Bacteria,COG0795@2|Bacteria,2IXP3@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_16
k59_55996_1	1303518.CCALI_01024	2.32e-15	73.9	COG0603@1|root,COG0603@2|Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
k59_55996_2	555778.Hneap_0538	1.51e-45	156.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1WW37@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_141201_1	313596.RB2501_03615	7.35e-90	294.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_187518_1	1121875.KB907556_gene572	3.6e-66	211.0	COG0823@1|root,COG0823@2|Bacteria,4NM2C@976|Bacteroidetes,1I7Q6@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_187520_1	880071.Fleli_1746	3.36e-19	91.7	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,47JV8@768503|Cytophagia	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_125735_1	1387312.BAUS01000007_gene2533	4.19e-57	200.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KKK3@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_117998_2	1046724.KB889875_gene1761	2.99e-21	94.7	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RQH7@1236|Gammaproteobacteria,469IK@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_234148_1	439235.Dalk_0586	1.71e-58	201.0	28HQ2@1|root,2Z7XV@2|Bacteria,1P4Z7@1224|Proteobacteria,42NSG@68525|delta/epsilon subdivisions,2WJ6K@28221|Deltaproteobacteria,2MJCF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_172109_1	465817.ETA_22510	2.86e-28	112.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,3X59R@551|Erwinia	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_133296_1	1196095.GAPWK_0470	9.11e-12	66.6	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Threonine synthase	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
k59_133296_2	1168034.FH5T_13815	1.26e-27	107.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FWAQ@200643|Bacteroidia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_226180_1	159087.Daro_0729	2.94e-33	132.0	COG0840@1|root,COG3829@1|root,COG5000@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
k59_79347_1	313596.RB2501_07560	1.12e-114	338.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_195298_1	926550.CLDAP_00560	3.21e-70	242.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
k59_33129_1	1168034.FH5T_06025	1e-34	125.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,2FN7D@200643|Bacteroidia	976|Bacteroidetes	G	Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
k59_33129_2	385682.AFSL01000014_gene2734	6.72e-28	108.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,2FN90@200643|Bacteroidia,3XJUJ@558415|Marinilabiliaceae	976|Bacteroidetes	H	Pantoate-beta-alanine ligase	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_149099_1	1235803.C825_02951	1.87e-06	58.2	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FWSR@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_203375_1	314230.DSM3645_09082	7.04e-25	97.1	COG1544@1|root,COG1544@2|Bacteria,2J1IM@203682|Planctomycetes	203682|Planctomycetes	J	modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_195665_1	926566.Terro_2751	2.55e-48	175.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria,2JI1K@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_118393_1	1122176.KB903544_gene718	7.71e-11	65.9	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1IQCU@117747|Sphingobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_118393_2	391625.PPSIR1_10315	3e-20	90.5	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_149105_1	986075.CathTA2_1600	1.89e-73	247.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_226490_1	690585.JNNU01000024_gene3936	2.12e-15	83.2	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,4B7KE@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
k59_203376_1	1168034.FH5T_17355	4.19e-95	298.0	COG0457@1|root,COG0457@2|Bacteria,4NFFS@976|Bacteroidetes,2FMYG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
k59_133679_1	1122603.ATVI01000011_gene1951	4.83e-19	79.3	2EK16@1|root,33DRP@2|Bacteria,1NMM2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_133679_2	1279009.ADICEAN_02365	2.43e-12	65.1	COG3668@1|root,COG3668@2|Bacteria,4NYUH@976|Bacteroidetes,47T6T@768503|Cytophagia	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_79631_1	395493.BegalDRAFT_1058	2.12e-66	227.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
k59_180243_1	1479238.JQMZ01000001_gene806	5.38e-10	61.6	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,43XE2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_187939_2	555779.Dthio_PD1485	3.66e-11	59.3	2EQIX@1|root,33I4Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
k59_110550_1	1537917.JU82_01990	1.58e-50	163.0	COG1144@1|root,COG1144@2|Bacteria,1NM08@1224|Proteobacteria,42SV1@68525|delta/epsilon subdivisions,2YPG8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_21
k59_110550_2	273121.WS2130	1.77e-41	146.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_33456_1	1168034.FH5T_14400	3.17e-91	276.0	COG4213@1|root,COG4213@2|Bacteria,4NNBW@976|Bacteroidetes,2FWT8@200643|Bacteroidia	976|Bacteroidetes	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
k59_226495_1	479433.Caci_6413	5.54e-17	82.8	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k59_226495_2	314345.SPV1_01767	3.3e-14	70.5	COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria	1224|Proteobacteria	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
k59_241995_2	768671.ThimaDRAFT_0084	3.05e-14	70.9	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1WYGC@135613|Chromatiales	135613|Chromatiales	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	-
k59_2356_1	1168034.FH5T_12605	3.4e-66	222.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia	976|Bacteroidetes	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_242000_1	234267.Acid_1536	6.15e-38	144.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_118394_1	335543.Sfum_1768	6.02e-48	176.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,42UA0@68525|delta/epsilon subdivisions,2WS4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
k59_234489_1	10224.XP_006826129.1	1.1e-181	564.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k59_87235_1	1499967.BAYZ01000154_gene1533	1.08e-70	221.0	COG0084@1|root,COG0084@2|Bacteria,2NP9H@2323|unclassified Bacteria	2|Bacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_218895_1	322710.Avin_01370	2.02e-09	58.2	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,1RNYE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_218895_3	377629.TERTU_0343	4.74e-11	62.8	28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,1RNYB@1236|Gammaproteobacteria,2PPP1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	H	Dinitrogenase reductase ADP-ribosyltransferase (DRAT)	draT	-	2.4.2.37	ko:K05951	-	-	-	-	ko00000,ko01000	-	-	-	DRAT
k59_234492_1	1123399.AQVE01000012_gene2964	1.16e-54	182.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,1SN1M@1236|Gammaproteobacteria,4639S@72273|Thiotrichales	72273|Thiotrichales	E	Homocysteine S-methyltransferase	-	-	2.1.1.5	ko:K00544	ko00260,ko00270,ko01100,map00260,map00270,map01100	-	R02821	RC00035,RC00496	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
k59_242020_1	266264.Rmet_0321	8.92e-27	109.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,2VP7Z@28216|Betaproteobacteria,1K505@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,HTH_Tnp_Mu_1,Mu-transpos_C,rve
k59_218902_1	768671.ThimaDRAFT_2651	1.65e-24	102.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_218902_2	768671.ThimaDRAFT_3358	1.84e-55	188.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1WXFT@135613|Chromatiales	135613|Chromatiales	M	D-Ala-D-Ala carboxypeptidase	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k59_17580_1	1515746.HR45_08965	6.78e-30	117.0	COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,2Q9G2@267890|Shewanellaceae	1236|Gammaproteobacteria	S	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:0090499,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	iBWG_1329.BWG_3103,iECBD_1354.ECBD_0333,iECDH10B_1368.ECDH10B_3587,iECDH1ME8569_1439.ECDH1ME8569_3291,iETEC_1333.ETEC_3662,iEcDH1_1363.EcDH1_0301,iJO1366.b3412,iY75_1357.Y75_RS20155	Abhydrolase_1,Abhydrolase_6
k59_79651_1	314230.DSM3645_11212	8.05e-41	155.0	COG1352@1|root,COG2201@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,2IWSR@203682|Planctomycetes	203682|Planctomycetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,PAS_9,Response_reg
k59_17581_1	1517416.IDAT_12995	5.14e-48	154.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S9EI@1236|Gammaproteobacteria,2QGI2@267893|Idiomarinaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_17581_2	1123236.KB899382_gene2308	8.51e-135	388.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,466E0@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_203396_1	644282.Deba_0734	1.37e-65	214.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_218910_1	1122599.AUGR01000006_gene3908	8.14e-22	99.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XIWX@135619|Oceanospirillales	135619|Oceanospirillales	K	membrane	rbn-1	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_172480_1	2340.JV46_16230	1.93e-95	286.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1J4D2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665	Pribosyl_synth,Pribosyltran_N
k59_10111_1	991905.SL003B_2679	9.45e-28	112.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,4BQFW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_79655_1	1565129.JSFF01000001_gene1164	9.63e-43	150.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RPVZ@1236|Gammaproteobacteria,2Q93D@267890|Shewanellaceae	1236|Gammaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_234504_1	387093.SUN_0016	4.11e-51	169.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_82740_1	1168034.FH5T_21935	2.38e-126	384.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,2FM76@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_237671_1	1547437.LL06_24935	3.21e-10	65.1	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2U2G6@28211|Alphaproteobacteria,43RDW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_113811_1	387093.SUN_0355	2.53e-38	140.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_113811_2	749222.Nitsa_0695	6.48e-70	214.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_245311_1	1123400.KB904746_gene1179	9.51e-27	106.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,45ZP8@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_75248_1	1122226.AUHX01000007_gene2672	2.27e-92	286.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_44207_1	1265505.ATUG01000002_gene1916	2.03e-68	213.0	2F8H0@1|root,340VU@2|Bacteria,1NZ5R@1224|Proteobacteria,430V9@68525|delta/epsilon subdivisions,2WW2K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_28703_2	1211819.CALK01000009_gene2799	3.29e-25	103.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,3VQK7@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_245317_1	1117314.PCIT_07407	9.06e-36	142.0	COG2304@1|root,COG2982@1|root,COG3637@1|root,COG4625@1|root,COG5492@1|root,COG2304@2|Bacteria,COG2982@2|Bacteria,COG3637@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,1QU09@1224|Proteobacteria,1T39R@1236|Gammaproteobacteria,2Q5JH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
k59_222236_1	1121405.dsmv_1598	1.19e-112	337.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WJVC@28221|Deltaproteobacteria,2MINJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_67593_1	1165841.SULAR_10089	1.36e-147	429.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_136955_1	159749.K0S7S3	6.23e-08	58.9	COG0793@1|root,2QSWI@2759|Eukaryota,2XA86@2836|Bacillariophyta	2836|Bacillariophyta	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41
k59_129435_1	1430440.MGMSRv2_1629	8.61e-44	162.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,2JR5R@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	6.3.2.14	ko:K02364	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
k59_152417_1	1379698.RBG1_1C00001G1818	0.000826	46.2	COG2067@1|root,COG2067@2|Bacteria,2NR34@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36729_1	5061.CADANGAP00007673	1.2e-17	83.2	COG1524@1|root,KOG2126@2759|Eukaryota,38C76@33154|Opisthokonta,3NU7J@4751|Fungi,3QMZ8@4890|Ascomycota,20DM0@147545|Eurotiomycetes,3S4I0@5042|Eurotiales	4751|Fungi	T	Phosphoethanolamine N-methyltransferase	GPI13	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009247,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0019538,GO:0019637,GO:0031224,GO:0031984,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0051377,GO:0071704,GO:0090407,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	-	ko:K05288	ko00563,ko01100,map00563,map01100	-	R05923,R08107	RC00017	ko00000,ko00001	-	-	-	Phosphodiest
k59_222244_1	1165841.SULAR_00080	5.34e-95	291.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_28714_1	1417296.U879_10575	4.81e-12	64.3	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_145246_1	1158182.KB905023_gene1453	5.08e-34	122.0	COG1487@1|root,COG1487@2|Bacteria,1N44Q@1224|Proteobacteria,1SD4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_68029_1	1384056.N787_08845	4.41e-17	88.2	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1X36S@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	xpsE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_13559_1	1165841.SULAR_01225	2.76e-118	344.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2YR33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_83156_1	1121920.AUAU01000022_gene2455	1.8e-85	265.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria	57723|Acidobacteria	J	PFAM tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_114264_1	502025.Hoch_1780	9.83e-121	371.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_230134_1	387093.SUN_1501	4.38e-24	101.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2YNPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_230134_2	1165841.SULAR_01370	1.81e-87	258.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2YPBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL,UPF0547
k59_199606_1	1129794.C427_4693	4.1e-60	193.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,469JR@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_75743_1	998674.ATTE01000001_gene272	4.78e-70	231.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,1SB7T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_184013_1	1121875.KB907553_gene59	3.72e-72	229.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_68030_1	1408433.JHXV01000008_gene58	8.56e-54	171.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,1I3D1@117743|Flavobacteriia,2PBSB@246874|Cryomorphaceae	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_145720_1	1168034.FH5T_18290	5.8e-114	337.0	COG3875@1|root,COG3875@2|Bacteria,4NI4Z@976|Bacteroidetes,2FQM8@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
k59_83159_1	396588.Tgr7_3218	5.39e-36	127.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans	fkpB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_83159_2	754477.Q7C_467	7.38e-12	63.2	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,460TI@72273|Thiotrichales	72273|Thiotrichales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_207078_2	879630.E1A287_9CAUD	1.81e-14	75.5	4QCR0@10239|Viruses,4QVAV@35237|dsDNA viruses  no RNA stage,4QPFK@28883|Caudovirales,4QI4N@10662|Myoviridae	10662|Myoviridae	S	cell wall macromolecule catabolic process	-	GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0016787,GO:0016798,GO:0019012,GO:0022607,GO:0033922,GO:0042802,GO:0043933,GO:0044085,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0051259,GO:0051260,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0061783,GO:0065003,GO:0070206,GO:0070207,GO:0071840,GO:0085027,GO:0098015,GO:0098025	-	-	-	-	-	-	-	-	-	-	-
k59_214854_1	395493.BegalDRAFT_1334	6.68e-78	244.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,45ZYQ@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_29218_3	439235.Dalk_3968	7.26e-20	89.4	COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
k59_191678_1	1304885.AUEY01000019_gene1184	6.14e-63	219.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,1RJUD@1224|Proteobacteria,42P27@68525|delta/epsilon subdivisions,2WK9Y@28221|Deltaproteobacteria,2MJZE@213118|Desulfobacterales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_8,TonB_dep_Rec,zinc_ribbon_4
k59_29222_1	1348583.ATLH01000005_gene924	4.34e-13	69.3	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_29222_2	313596.RB2501_10507	2.49e-64	201.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HYCK@117743|Flavobacteriia	976|Bacteroidetes	H	gtp cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_13561_1	765912.Thimo_2782	2.94e-30	114.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales	135613|Chromatiales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_6012_2	1340493.JNIF01000003_gene2732	6.64e-30	115.0	COG2096@1|root,COG2096@2|Bacteria,3Y83S@57723|Acidobacteria	57723|Acidobacteria	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
k59_29223_2	1165841.SULAR_04437	2.87e-63	197.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065	OstA
k59_129890_1	90675.XP_010470739.1	7.62e-123	379.0	COG2801@1|root,KOG1121@1|root,KOG0017@2759|Eukaryota,KOG1121@2759|Eukaryota	2759|Eukaryota	E	protein dimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4413,Dimer_Tnp_hAT,zf-BED
k59_191686_1	1082932.ATCR1_08239	2.74e-30	115.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,4BBRE@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Two component transcriptional regulator	-	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_83167_1	1165841.SULAR_07430	2.13e-110	328.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2YMA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_230150_1	1144275.COCOR_00403	7.44e-14	76.3	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2Z33Y@29|Myxococcales	28221|Deltaproteobacteria	M	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_160647_1	502025.Hoch_0458	2.96e-47	170.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,438QJ@68525|delta/epsilon subdivisions,2X3XW@28221|Deltaproteobacteria,2YXIE@29|Myxococcales	28221|Deltaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
k59_90923_1	313596.RB2501_09170	1.72e-86	262.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_90928_1	629265.PMA4326_29130	2.57e-05	46.2	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1Z5G6@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	I	Malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
k59_90928_2	1268635.Loa_02153	1.15e-39	132.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1JF0M@118969|Legionellales	118969|Legionellales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_137404_1	259536.Psyc_0382	1.59e-06	51.6	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria,3NJ8C@468|Moraxellaceae	1236|Gammaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
k59_137404_2	471223.GWCH70_1582	1.63e-40	139.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1WG4V@129337|Geobacillus	91061|Bacilli	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	dfrA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
k59_129902_1	247490.KSU1_C1449	1.31e-71	228.0	28HMZ@1|root,2Z7WD@2|Bacteria,2J2EK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_114287_2	1229781.C272_00905	3.37e-08	54.7	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4F91E@85019|Brevibacteriaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_207096_1	1123057.P872_14770	3.43e-31	124.0	2BUK2@1|root,32PWK@2|Bacteria,4NKNA@976|Bacteroidetes,47NMG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_90934_1	2340.JV46_26640	9.14e-143	438.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_114288_1	153948.NAL212_1046	7.71e-07	57.4	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	chiS	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GGDEF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_160659_2	46234.ANA_C20118	1.39e-27	119.0	COG0683@1|root,COG1672@1|root,COG0683@2|Bacteria,COG1672@2|Bacteria,1G4E9@1117|Cyanobacteria	1117|Cyanobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	AAA_16,Peripla_BP_6
k59_214886_1	387093.SUN_1164	1.08e-95	308.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_152922_1	314292.VAS14_06843	1.66e-34	138.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,1XT7J@135623|Vibrionales	135623|Vibrionales	L	COG0419 ATPase involved in DNA repair	sbcC	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006260,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
k59_6054_1	1353529.M899_0620	2.24e-17	84.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2MT5M@213481|Bdellovibrionales,2WJE1@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_6054_2	909613.UO65_5456	7.66e-55	190.0	COG0318@1|root,COG0318@2|Bacteria,2IBJ8@201174|Actinobacteria,4EA9B@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_83198_1	1278307.KB907000_gene328	4.25e-31	114.0	2EH8A@1|root,33B04@2|Bacteria,1NXJT@1224|Proteobacteria,1SPRU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_106379_2	1168034.FH5T_10410	6.95e-82	270.0	COG0841@1|root,COG1131@1|root,COG0841@2|Bacteria,COG1131@2|Bacteria,4NF8M@976|Bacteroidetes,2FQY7@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ACR_tran
k59_114294_1	1397527.Q670_05460	1.84e-68	218.0	COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1XHP1@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_164035_1	926556.Echvi_2076	3.23e-97	290.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,47MD1@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_233831_1	519989.ECTPHS_11350	4.91e-74	230.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1WXGF@135613|Chromatiales	135613|Chromatiales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_171808_1	1168034.FH5T_16475	1.66e-43	146.0	2ER78@1|root,33ISU@2|Bacteria,4NZKM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_171808_2	997884.HMPREF1068_01925	1.85e-12	66.6	COG1595@1|root,COG1595@2|Bacteria,4NS8T@976|Bacteroidetes,2FRUY@200643|Bacteroidia,4APDC@815|Bacteroidaceae	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_48060_1	1279009.ADICEAN_00003	1.67e-65	218.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_125436_1	1190606.AJYG01000016_gene3419	6.11e-16	82.8	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1QXXY@1224|Proteobacteria,1T5JT@1236|Gammaproteobacteria,1XYJ1@135623|Vibrionales	135623|Vibrionales	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k59_55782_1	3880.AES61810	2.71e-16	79.7	28VD5@1|root,2R24N@2759|Eukaryota,38A1H@33090|Viridiplantae,3GR50@35493|Streptophyta	3880.AES61810|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79018_1	2340.JV46_17220	7.27e-121	354.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1J50Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	related to Ser Thr protein kinases	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_71135_1	397945.Aave_4518	4.06e-85	267.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2VHTR@28216|Betaproteobacteria,4AB3G@80864|Comamonadaceae	28216|Betaproteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_133073_1	1121859.KB890759_gene1894	0.000913	42.7	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,47KP1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_109922_1	754477.Q7C_1950	6.69e-75	239.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,45ZMM@72273|Thiotrichales	72273|Thiotrichales	F	TIGRFAM dihydroorotase, multifunctional complex type	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_148477_1	1165841.SULAR_01883	7.14e-35	122.0	COG4276@1|root,COG4276@2|Bacteria,1N2Z3@1224|Proteobacteria,42THP@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_140908_1	472759.Nhal_3674	5.26e-10	63.5	COG3551@1|root,COG3551@2|Bacteria,1MYJC@1224|Proteobacteria,1S8FM@1236|Gammaproteobacteria,1X1UW@135613|Chromatiales	135613|Chromatiales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_48509_1	1122194.AUHU01000003_gene2334	0.000376	44.7	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4642R@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_48509_2	566466.NOR53_3370	2.48e-33	119.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1JARD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_226345_1	247634.GPB2148_3209	3.28e-71	237.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1J4CD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_87118_1	866536.Belba_1195	5.57e-64	204.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF1906,PG_binding_1,Peptidase_M15_4
k59_87118_2	1049564.TevJSym_ab01040	2.22e-07	52.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1J4DR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_164591_1	519989.ECTPHS_02901	2.16e-20	91.3	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	ygaU	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0030955,GO:0031420,GO:0035864,GO:0040008,GO:0040009,GO:0040010,GO:0042221,GO:0043167,GO:0043169,GO:0045927,GO:0046872,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007	-	ko:K21687,ko:K21688,ko:K21689,ko:K21690,ko:K21691	-	-	-	-	ko00000	-	GH23	-	LysM,Peptidase_M23,Transglycosylas
k59_9922_1	591001.Acfer_1389	2.33e-11	68.9	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H2JV@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_187741_1	1304883.KI912532_gene38	2.3e-37	141.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,2KUDS@206389|Rhodocyclales	206389|Rhodocyclales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_63927_1	1144275.COCOR_05003	2.23e-68	219.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_102489_1	1278307.KB907070_gene2698	3.16e-15	79.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transposase, IS801 IS1294	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_102489_2	243277.VC_A0388	2.78e-07	54.7	2C5W3@1|root,2ZIHN@2|Bacteria,1PAFZ@1224|Proteobacteria,1SUZR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40846_1	1165841.SULAR_06748	1.44e-44	150.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2YN11@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_40846_2	1165841.SULAR_06743	9.19e-40	142.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2YMBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_180066_2	994479.GL877878_gene2063	1.16e-06	51.2	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4E1BI@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Ketoacyl-synt_C,Methyltransf_12,Methyltransf_23,Nitroreductase,PP-binding,Thioesterase,ketoacyl-synt
k59_102501_1	1165841.SULAR_10684	3.06e-147	425.0	COG3245@1|root,COG3258@1|root,COG3245@2|Bacteria,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,42WAQ@68525|delta/epsilon subdivisions,2YTG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
k59_187749_3	1357714.A0A067XR07_9CAUD	7.67e-14	73.6	4QBKS@10239|Viruses,4QV8M@35237|dsDNA viruses  no RNA stage,4QPK5@28883|Caudovirales,4QIYJ@10662|Myoviridae	10662|Myoviridae	S	Base plate wedge protein 53	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_203193_1	1168034.FH5T_05290	2e-46	164.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,2FPVW@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
k59_203193_3	1168034.FH5T_05325	6.98e-57	183.0	28PU4@1|root,2ZCF6@2|Bacteria,4NTXA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40852_2	313624.NSP_14380	5.93e-27	100.0	COG2886@1|root,COG2886@2|Bacteria,1G8FV@1117|Cyanobacteria,1HPCD@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
k59_141327_1	530564.Psta_3907	6.66e-90	275.0	COG0448@1|root,COG0448@2|Bacteria,2IWRQ@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_164605_1	980584.AFPB01000171_gene1528	2.77e-40	154.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,406X3@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_17463_1	1165841.SULAR_01360	1.08e-96	309.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_203195_1	1168034.FH5T_13790	8.5e-57	179.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,2FNTB@200643|Bacteroidia	976|Bacteroidetes	O	AhpC Tsa family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_203195_2	1168034.FH5T_13795	5.65e-63	201.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,2FN5D@200643|Bacteroidia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_172292_1	1209072.ALBT01000011_gene3204	8.23e-77	239.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1FGZ3@10|Cellvibrio	1236|Gammaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_9933_1	1165841.SULAR_09739	7.07e-78	239.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42QPW@68525|delta/epsilon subdivisions,2YP0Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2190_1	1117319.PSPO_20376	3.51e-08	63.5	COG3343@1|root,COG5183@1|root,COG3343@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,2Q202@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	AK	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
k59_195502_1	497965.Cyan7822_1520	4.31e-12	67.0	COG2146@1|root,COG2146@2|Bacteria,1G6WX@1117|Cyanobacteria,3KI7W@43988|Cyanothece	1117|Cyanobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
k59_40855_1	1165841.SULAR_01813	1.99e-102	302.0	COG0715@1|root,COG0715@2|Bacteria,1MVRA@1224|Proteobacteria,42M17@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	NMT1/THI5 like	thi	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
k59_40855_2	1165841.SULAR_01808	4.69e-84	252.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42TAK@68525|delta/epsilon subdivisions,2YPP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_133512_1	2340.JV46_05750	5.19e-130	385.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1J523@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_63936_1	136993.KB900626_gene1229	2.13e-63	201.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_25291_2	465541.ATCJ01000001_gene460	2.98e-11	67.0	COG1028@1|root,COG1028@2|Bacteria,2GKE1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_226357_2	3880.AES58577	3.36e-305	861.0	COG0056@1|root,COG0356@1|root,COG1622@1|root,KOG1353@2759|Eukaryota,KOG4665@2759|Eukaryota,KOG4767@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta,4JSJY@91835|fabids	35493|Streptophyta	C	ATP synthase	atp1	-	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,COX2_TM
k59_110370_2	1238182.C882_2346	3.35e-06	50.4	COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,2TUC6@28211|Alphaproteobacteria,2JRHR@204441|Rhodospirillales	204441|Rhodospirillales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_79512_1	1165841.SULAR_00090	1.31e-14	71.6	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2YN1Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_79512_2	1165841.SULAR_00095	1.09e-102	313.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_118266_1	246195.DNO_0154	1.15e-06	53.5	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_133520_1	1382359.JIAL01000001_gene2922	7.3e-56	199.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_218741_1	261292.Nit79A3_0465	4.59e-42	149.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,372EJ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_79518_2	411490.ANACAC_01183	4.36e-30	114.0	COG4925@1|root,COG4925@2|Bacteria,1V9AI@1239|Firmicutes,24PAJ@186801|Clostridia	186801|Clostridia	I	sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclophil_like
k59_40881_1	1268635.Loa_00363	5.69e-17	80.1	COG0262@1|root,COG1995@1|root,COG0262@2|Bacteria,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1JCGN@118969|Legionellales	118969|Legionellales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_40881_2	2340.JV46_11630	1.45e-74	224.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1J6BH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_56209_2	572477.Alvin_3302	8.86e-14	74.3	COG5527@1|root,COG5527@2|Bacteria,1R7A6@1224|Proteobacteria,1RQMU@1236|Gammaproteobacteria,1X0XK@135613|Chromatiales	135613|Chromatiales	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
k59_156719_2	5786.XP_003285768.1	6.5e-12	68.2	COG1748@1|root,KOG0172@2759|Eukaryota,3XCSB@554915|Amoebozoa	554915|Amoebozoa	E	Saccharopine dehydrogenase C-terminal domain	-	GO:0003674,GO:0003824,GO:0004753,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_9949_1	378806.STAUR_4207	1.6e-32	130.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUE5@29|Myxococcales	28221|Deltaproteobacteria	D	HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
k59_195517_2	102107.XP_008244832.1	4.06e-62	192.0	2C63X@1|root,2S2ZC@2759|Eukaryota,37VFD@33090|Viridiplantae,3GJPI@35493|Streptophyta,4JW29@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_195517_3	4537.OPUNC12G12590.1	1.41e-103	310.0	COG1845@1|root,KOG4664@2759|Eukaryota,37QER@33090|Viridiplantae,3G8C5@35493|Streptophyta,3M3PB@4447|Liliopsida,3ICZ5@38820|Poales	35493|Streptophyta	C	cytochrome c oxidase subunit 3	cox3	-	-	ko:K02262	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX3,Mt_ATP-synt_B
k59_218754_1	1121875.KB907547_gene3502	1.54e-85	263.0	COG5571@1|root,COG5571@2|Bacteria,4NMTM@976|Bacteroidetes,1I1Q2@117743|Flavobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
k59_210922_1	1122201.AUAZ01000014_gene217	1.95e-19	90.1	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,465A2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	nucleoside-diphosphate sugar epimerase	yfcH	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_210922_2	1121948.AUAC01000002_gene1079	7.34e-24	99.8	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,2TSHW@28211|Alphaproteobacteria,43WIU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
k59_126020_2	1041930.Mtc_1044	1.49e-31	120.0	COG0524@1|root,arCOG00014@2157|Archaea	2157|Archaea	G	Belongs to the carbohydrate kinase PfkB family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704	2.7.1.15,2.7.1.213	ko:K00852,ko:K21057	ko00030,ko00240,map00030,map00240	-	R00513,R00964,R01051,R01666,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_207030_1	69014.TK1334	3.71e-17	82.4	COG0237@1|root,arCOG01045@2157|Archaea,2XWNJ@28890|Euryarchaeota,2433T@183968|Thermococci	183968|Thermococci	H	Belongs to the UPF0200 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17
k59_52282_1	316274.Haur_3607	3.09e-15	72.8	COG4392@1|root,COG4392@2|Bacteria	2|Bacteria	E	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
k59_207031_1	948870.I7HXL0_9CAUD	1.06e-09	60.1	4QDCQ@10239|Viruses,4QVJW@35237|dsDNA viruses  no RNA stage,4QPZZ@28883|Caudovirales,4QICG@10662|Myoviridae	10662|Myoviridae	S	Domain of unknown function (DUF1768)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_122517_1	1348583.ATLH01000005_gene947	1.45e-77	259.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia,1F7TZ@104264|Cellulophaga	976|Bacteroidetes	KT	PFAM Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
k59_199892_1	4572.TRIUR3_00079-P1	8.59e-131	410.0	COG0086@1|root,2QPYA@2759|Eukaryota,37HSD@33090|Viridiplantae,3GDVE@35493|Streptophyta,3KV60@4447|Liliopsida,3I5C8@38820|Poales	35493|Streptophyta	K	DNA-directed RNA polymerase	rpoC2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_246009_1	313596.RB2501_05000	1.5e-100	309.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
k59_76045_1	483219.LILAB_10245	3.51e-43	151.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2YZEX@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_60387_1	768671.ThimaDRAFT_3239	1.35e-38	146.0	COG2244@1|root,COG2244@2|Bacteria,1PF64@1224|Proteobacteria,1TKCZ@1236|Gammaproteobacteria,1X1Y8@135613|Chromatiales	135613|Chromatiales	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_238396_1	718252.FP2_22550	2.81e-09	62.8	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_83455_1	1165841.SULAR_01345	2.05e-101	318.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_122518_1	1173027.Mic7113_1195	1.88e-42	167.0	COG0784@1|root,COG3437@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_122518_2	1173024.KI912151_gene1538	2.07e-81	270.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JJEC@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_184308_1	1121355.KB903379_gene760	2.89e-05	45.4	COG2510@1|root,COG2510@2|Bacteria,2HW2B@201174|Actinobacteria,22Q8K@1653|Corynebacteriaceae	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
k59_114531_1	933262.AXAM01000005_gene2500	5e-29	105.0	2E4K0@1|root,32ZEZ@2|Bacteria,1NEXM@1224|Proteobacteria,42W2R@68525|delta/epsilon subdivisions,2WRPN@28221|Deltaproteobacteria,2MNZH@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114531_2	879212.DespoDRAFT_01111	2.83e-31	112.0	arCOG07672@1|root,31TNR@2|Bacteria,1NYF2@1224|Proteobacteria,430G1@68525|delta/epsilon subdivisions,2WVYV@28221|Deltaproteobacteria,2MNKZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
k59_153148_1	1565129.JSFF01000006_gene2557	1.71e-06	48.9	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,2QAZB@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	caiC	GO:0003674,GO:0003824,GO:0016405,GO:0016874,GO:0016877,GO:0016879,GO:0016881,GO:0051108,GO:0051109	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	iECSE_1348.ECSE_0038,iNRG857_1313.NRG857_00195	AMP-binding,AMP-binding_C
k59_153148_2	1565129.JSFF01000006_gene2558	1.05e-82	246.0	COG2030@1|root,COG2030@2|Bacteria,1REMU@1224|Proteobacteria,1SZIU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_76051_1	313596.RB2501_02670	1.91e-38	137.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_76051_2	886377.Murru_2047	1.48e-74	234.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_52566_2	395493.BegalDRAFT_0379	8.78e-29	106.0	COG2456@1|root,COG2456@2|Bacteria,1R3JB@1224|Proteobacteria,1T68R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
k59_230422_1	1123393.KB891316_gene1365	7.65e-87	273.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,1KS0Q@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_215135_1	1165841.SULAR_01783	4.26e-131	377.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2YMPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_222984_1	1894.JOER01000019_gene4205	1.32e-09	62.4	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_3
k59_13839_1	1116472.MGMO_91c00070	3.45e-26	109.0	COG2370@1|root,COG4206@1|root,COG2370@2|Bacteria,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,1RPBH@1236|Gammaproteobacteria,1XH1C@135618|Methylococcales	135618|Methylococcales	HO	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ,Plug,TonB_dep_Rec
k59_207338_1	1168034.FH5T_04710	1.38e-84	256.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase, S54 family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
k59_52569_1	2340.JV46_26640	4.46e-105	334.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_6362_1	1168034.FH5T_05580	2.1e-88	276.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,2FNK9@200643|Bacteroidia	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_238401_1	1051646.VITU9109_08296	4.48e-06	46.2	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1XWXC@135623|Vibrionales	135623|Vibrionales	J	translation initiation inhibitor, yjgF family	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_114538_1	1122201.AUAZ01000015_gene729	3.74e-25	104.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,46AEQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II/IV secretion system protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_29592_2	1267534.KB906757_gene1063	6.39e-11	62.8	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_6368_1	395493.BegalDRAFT_0428	1.05e-14	72.8	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4608W@72273|Thiotrichales	72273|Thiotrichales	M	Lytic murein transglycosylase B	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_6368_2	566466.NOR53_2788	4.42e-17	82.8	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1J8K3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_160961_1	1165841.SULAR_03267	2.41e-58	185.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2YMH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_153158_1	317025.Tcr_0935	8.59e-103	308.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,460RS@72273|Thiotrichales	72273|Thiotrichales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k59_192002_1	1125700.HMPREF9195_00236	7.44e-19	94.0	COG1199@1|root,COG1199@2|Bacteria,2J626@203691|Spirochaetes	203691|Spirochaetes	L	Helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RadC,ResIII
k59_114548_1	1565314.OA34_02480	1.08e-19	87.8	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,42QZE@68525|delta/epsilon subdivisions,2YSAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TPM domain	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
k59_29600_1	1056820.KB900640_gene273	1.19e-41	156.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,2PQ0B@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_160962_1	1430440.MGMSRv2_1304	2.36e-45	159.0	COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales	204441|Rhodospirillales	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_52582_1	448385.sce4077	2.69e-89	298.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2X7WN@28221|Deltaproteobacteria,2YXQ6@29|Myxococcales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_13867_1	1279019.ARQK01000012_gene147	1.66e-66	216.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,1WVZB@135613|Chromatiales	135613|Chromatiales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_13867_2	1046714.AMRX01000008_gene896	4.41e-19	85.5	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,466CP@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_184333_1	396588.Tgr7_0514	5e-139	400.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1WW91@135613|Chromatiales	135613|Chromatiales	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_83474_1	765910.MARPU_03755	3.18e-62	192.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1WY6U@135613|Chromatiales	135613|Chromatiales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_83474_2	2340.JV46_07290	5.24e-24	92.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1J6WB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_83474_3	765913.ThidrDRAFT_1746	1.08e-37	128.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1WZA0@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_207354_1	1336245.JAGO01000010_gene678	8.32e-30	110.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1XM4S@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_184344_1	395493.BegalDRAFT_0744	2.93e-78	261.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	395493.BegalDRAFT_0744|-	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_29602_1	1123236.KB899394_gene3154	2.58e-51	182.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,468ST@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_130192_1	1165841.SULAR_07555	6.09e-21	91.3	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_130192_2	1165841.SULAR_07550	3.06e-88	273.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_106670_1	1408473.JHXO01000006_gene1215	1.19e-06	57.8	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,2FMUF@200643|Bacteroidia	976|Bacteroidetes	CP	ABC transporter permease	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_21642_1	1117315.AHCA01000001_gene2216	7.91e-171	502.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,2Q03M@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_91262_1	1535422.ND16A_3395	1.65e-10	67.0	COG1506@1|root,COG1506@2|Bacteria,1MWFI@1224|Proteobacteria,1RPJD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
k59_246047_1	234267.Acid_4092	2.98e-23	96.3	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_184352_1	472759.Nhal_3933	1.51e-17	87.8	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1X0CU@135613|Chromatiales	135613|Chromatiales	H	HemY domain protein	-	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
k59_76083_1	2340.JV46_03470	3.66e-81	253.0	COG0845@1|root,COG0845@2|Bacteria,1MWZ9@1224|Proteobacteria,1RM91@1236|Gammaproteobacteria,1JBVB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_91265_1	1224136.AMFN01000003_gene3477	1.04e-114	337.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,282UH@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47,4.2.1.22	ko:K01697,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2444	PALP
k59_83488_1	1165841.SULAR_09069	1.12e-49	173.0	COG3087@1|root,COG3087@2|Bacteria	2|Bacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K03591	-	-	-	-	ko00000,ko03036	-	-	-	NYN,SPOR
k59_184359_2	1265313.HRUBRA_00004	9.76e-24	91.7	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1J6MB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_184359_3	472759.Nhal_3499	2.04e-29	107.0	COG0724@1|root,COG0724@2|Bacteria,1NDEM@1224|Proteobacteria,1SFDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_160977_1	665942.HMPREF1022_02940	1.52e-57	229.0	COG0553@1|root,COG0827@1|root,COG1040@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG4646@2|Bacteria,1PGZG@1224|Proteobacteria,42NYW@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	COG0827 Adenine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,Helicase_C,N6_Mtase,ResIII,SNF2_N
k59_37486_1	696747.NIES39_A01590	2.47e-23	102.0	COG0826@1|root,COG0826@2|Bacteria,1G1AA@1117|Cyanobacteria,1HA5Y@1150|Oscillatoriales	1117|Cyanobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_83495_1	546414.Deide_14270	2.7e-06	48.9	COG0521@1|root,COG0521@2|Bacteria,1WIRM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Molybdenum cofactor biosynthesis protein B	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_83495_2	392500.Swoo_3262	4.08e-25	107.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2QB6M@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_153180_1	3659.XP_004154167.1	3.46e-153	436.0	COG0843@1|root,2S5UM@2759|Eukaryota	2759|Eukaryota	C	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
k59_37494_1	1123057.P872_11715	2.18e-62	215.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
k59_91281_1	1472716.KBK24_0137140	1.73e-67	220.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,1K0ER@119060|Burkholderiaceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
k59_153182_1	1190603.AJYD01000015_gene912	5.65e-59	184.0	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,1S8YM@1236|Gammaproteobacteria,1XY2Z@135623|Vibrionales	135623|Vibrionales	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_223016_1	207559.Dde_0865	2.38e-33	138.0	COG1203@1|root,COG1203@2|Bacteria,1MX99@1224|Proteobacteria,42NPE@68525|delta/epsilon subdivisions,2WJKI@28221|Deltaproteobacteria,2MAX5@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	helicase Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
k59_146079_1	886377.Murru_1808	2.09e-36	127.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1HYCZ@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_146079_2	1121875.KB907550_gene872	5.18e-102	296.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,1I1CY@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_146079_3	1121875.KB907550_gene873	2.18e-18	82.4	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_192031_1	2340.JV46_10170	4.69e-165	467.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1J545@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iJN746.PP_4253	Cytochrome_CBB3,FixP_N
k59_226869_1	395493.BegalDRAFT_0800	7.32e-57	181.0	2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141842_1	1120966.AUBU01000016_gene3070	1.3e-110	367.0	COG1361@1|root,COG2911@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,4PPBJ@976|Bacteroidetes,47TYA@768503|Cytophagia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95493_1	670307.HYPDE_24348	6.53e-12	70.9	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,3N65N@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_72148_1	1283076.M1I7U4_9CAUD	4.85e-20	94.0	4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses  no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage T4-like capsid assembly protein (Gp20)	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_41388_1	1165841.SULAR_07585	1.83e-112	347.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_103085_2	585.DR95_2741	9.36e-17	80.1	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,3Z1BT@583|Proteus	1236|Gammaproteobacteria	P	Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K( ) H( ) antiport	kefB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	iB21_1397.B21_03153,iEC55989_1330.EC55989_3754,iECBD_1354.ECBD_0398,iECB_1328.ECB_03201,iECD_1391.ECD_03201,iECO26_1355.ECO26_4439,iECSE_1348.ECSE_3612,iECW_1372.ECW_m3606,iEKO11_1354.EKO11_0394,iEcHS_1320.EcHS_A3547,iSFV_1184.SFV_3356,iSSON_1240.SSON_3481,iWFL_1372.ECW_m3606,iYL1228.KPN_03736	Na_H_Exchanger,TrkA_N
k59_157280_1	713586.KB900536_gene2937	4.16e-77	248.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1WXDW@135613|Chromatiales	135613|Chromatiales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_25793_1	387093.SUN_0573	6.63e-134	384.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2YN8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fumarate hydratase	ttdA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
k59_141849_1	2340.JV46_27550	6.49e-56	181.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_141849_2	2340.JV46_27560	2.03e-53	170.0	COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	VV0993	-	-	-	-	-	-	-	-	-	-	-	-
k59_110868_1	1117647.M5M_02195	1.29e-40	146.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1J4FK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NT	COG0835 Chemotaxis signal transduction protein	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_226880_1	1506583.JQJY01000010_gene1174	2.05e-22	99.4	COG0457@1|root,COG0457@2|Bacteria,4NH2F@976|Bacteroidetes,1HZ6Z@117743|Flavobacteriia,2NZXQ@237|Flavobacterium	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_10515_1	1353529.M899_2030	2.02e-95	300.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42NDG@68525|delta/epsilon subdivisions,2MSS8@213481|Bdellovibrionales,2WKYU@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_87639_2	1128427.KB904821_gene4236	1.48e-29	124.0	COG0464@1|root,COG0464@2|Bacteria,1G2M7@1117|Cyanobacteria,1HE1K@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_41405_1	1165841.SULAR_01180	2.29e-100	292.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM SEC-C motif domain protein	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_41405_2	387093.SUN_1474	1.18e-40	140.0	COG1853@1|root,COG1853@2|Bacteria,1PD46@1224|Proteobacteria,42T15@68525|delta/epsilon subdivisions,2YPFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_180665_1	1265505.ATUG01000002_gene1874	2.41e-82	258.0	COG4191@1|root,COG4191@2|Bacteria,1R6WR@1224|Proteobacteria,42PFK@68525|delta/epsilon subdivisions,2WJSP@28221|Deltaproteobacteria,2MHRP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_33827_1	313596.RB2501_04060	1.45e-52	171.0	28JKT@1|root,2Z9DG@2|Bacteria,4NJJK@976|Bacteroidetes,1HYPI@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
k59_172797_1	388413.ALPR1_02205	7.13e-25	108.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_41419_1	240016.ABIZ01000001_gene460	4.73e-09	57.8	COG2755@1|root,COG2755@2|Bacteria,46Z4E@74201|Verrucomicrobia,2IU1Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
k59_95504_1	4555.Si020883m	4.32e-20	80.5	2C8JW@1|root,2SBI8@2759|Eukaryota,37XIV@33090|Viridiplantae,3GMK0@35493|Streptophyta,3M8NW@4447|Liliopsida	35493|Streptophyta	S	Photosystem II protein J	psbJ	-	-	ko:K02711	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbJ
k59_95504_2	4565.EPlTAEP00000010029	1.48e-21	84.0	2E87T@1|root,2SEUE@2759|Eukaryota,37XI9@33090|Viridiplantae,3GMTY@35493|Streptophyta,3M1DX@4447|Liliopsida	35493|Streptophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02708	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559
k59_95504_3	13333.ERN02869	5.52e-54	171.0	2CHYC@1|root,2S3QA@2759|Eukaryota,37V66@33090|Viridiplantae,3GJP6@35493|Streptophyta	35493|Streptophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbE	-	-	ko:K02707,ko:K02713	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559,Cytochrom_B559a,PsbL
k59_95504_4	4081.Solyc01g067760.1.1	1.32e-24	93.2	2DZSX@1|root,2S79R@2759|Eukaryota,37WT4@33090|Viridiplantae,3GUGA@35493|Streptophyta,44UJ2@71274|asterids	35493|Streptophyta	C	Photosystem I reaction center subunit IX	-	-	-	ko:K02697	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PSI_PsaJ
k59_95504_5	29730.Gorai.010G129700.1	4.86e-54	170.0	KOG3162@1|root,KOG3162@2759|Eukaryota,37WM8@33090|Viridiplantae,3GJCQ@35493|Streptophyta	35493|Streptophyta	J	30S ribosomal protein S18, chloroplastic	rps18	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_95504_6	4081.Solyc01g007470.1.1	1.77e-75	227.0	COG0292@1|root,KOG4707@2759|Eukaryota,37VVT@33090|Viridiplantae,3GJCY@35493|Streptophyta	35493|Streptophyta	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rpl20	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0031967,GO:0031975,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_95504_7	59689.fgenesh1_pm.C_scaffold_2000590	2.94e-41	139.0	COG0740@1|root,KOG0840@2759|Eukaryota,37U4N@33090|Viridiplantae,3GICU@35493|Streptophyta	35493|Streptophyta	O	ATP-dependent Clp protease proteolytic subunit	clpP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_95504_8	57918.XP_004309412.1	1.39e-75	227.0	COG0740@1|root,KOG0840@2759|Eukaryota,37U4N@33090|Viridiplantae,3GICU@35493|Streptophyta,4JUJ9@91835|fabids	35493|Streptophyta	O	ATP-dependent Clp protease proteolytic	clpP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_95504_9	3880.AES88252	1.84e-36	135.0	COG1290@1|root,KOG4663@2759|Eukaryota,37QS7@33090|Viridiplantae,3GHBB@35493|Streptophyta,4JPQB@91835|fabids	35493|Streptophyta	C	cytochrome b6	petB	-	-	ko:K02635,ko:K02704	ko00195,ko01100,map00195,map01100	M00161,M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_10529_1	526222.Desal_2606	1.8e-116	347.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2M8U2@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_64498_1	338966.Ppro_1493	3.98e-104	315.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2WJPR@28221|Deltaproteobacteria,43U0K@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_188347_1	395019.Bmul_1229	2.13e-23	98.6	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,1K38Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k59_188347_2	1238450.VIBNISOn1_1160108	8.3e-26	105.0	COG1396@1|root,COG1396@2|Bacteria,1R3Z8@1224|Proteobacteria,1RRMV@1236|Gammaproteobacteria,1XVVD@135623|Vibrionales	135623|Vibrionales	K	Protein of unknown function (DUF3612)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3612,HTH_3,Peptidase_M78
k59_103104_1	313596.RB2501_05265	9.58e-88	271.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1HXKA@117743|Flavobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_110881_1	1168034.FH5T_06775	1.37e-96	285.0	COG1917@1|root,COG1917@2|Bacteria,4NMER@976|Bacteroidetes,2G0DI@200643|Bacteroidia	976|Bacteroidetes	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
k59_56683_1	351348.Maqu_4228	3.55e-133	382.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,4679W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_56683_2	1255043.TVNIR_0911	7.42e-60	198.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1WYPQ@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_2728_1	2340.JV46_26060	1.93e-98	298.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1J4S7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_234884_1	876044.IMCC3088_2206	2.31e-23	97.4	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_234884_2	272624.lpg2421	1.73e-39	140.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,1JFMM@118969|Legionellales	118969|Legionellales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_172815_1	1283300.ATXB01000001_gene1193	2.64e-05	46.6	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_172815_2	675814.VIC_004508	6.31e-06	50.4	2DM7V@1|root,323W3@2|Bacteria,1NPYM@1224|Proteobacteria,1SJ13@1236|Gammaproteobacteria,1XY2N@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
k59_141874_1	1250232.JQNJ01000001_gene1965	9.96e-35	123.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1HYRH@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_141874_3	313596.RB2501_03840	7.88e-32	124.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_242447_1	1249627.D779_1971	1.09e-13	70.1	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_157322_1	1121937.AUHJ01000010_gene1660	4.65e-64	202.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,4655B@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_110883_1	685035.ADAE01000020_gene1469	9.09e-49	175.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,2K1DA@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_141878_1	395493.BegalDRAFT_3104	9.32e-142	415.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,45ZY1@72273|Thiotrichales	72273|Thiotrichales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_188356_1	1168034.FH5T_17985	3.06e-93	293.0	COG2207@1|root,COG3063@1|root,COG5616@1|root,COG2207@2|Bacteria,COG3063@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
k59_10555_1	1385513.N780_10620	2.26e-58	188.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,2YAAA@289201|Pontibacillus	91061|Bacilli	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15560	Pribosyltran
k59_219276_1	2340.JV46_19780	4.95e-109	330.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1J4YI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease YjgP/YjgQ family	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_196176_1	504472.Slin_2494	3.93e-55	184.0	COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_25834_1	398578.Daci_3799	4.78e-16	87.8	COG1672@1|root,COG1672@2|Bacteria,1NIID@1224|Proteobacteria,2W5ZH@28216|Betaproteobacteria,4AIPY@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_211451_1	1279009.ADICEAN_03711	2.89e-69	220.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149554_1	338966.Ppro_0219	6.72e-62	199.0	COG2378@1|root,COG2378@2|Bacteria,1R65H@1224|Proteobacteria,42PYW@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
k59_56699_2	3847.GLYMA0405S00215.1	3.46e-33	121.0	COG0199@1|root,KOG1741@2759|Eukaryota,3896F@33090|Viridiplantae,3GY3H@35493|Streptophyta,4JWAW@91835|fabids	35493|Streptophyta	J	Ribosomal protein S14p/S29e	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S14
k59_234888_1	1165841.SULAR_03098	1.76e-117	353.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_227251_1	716541.ECL_01383	1.48e-40	144.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,1RRDM@1236|Gammaproteobacteria,3X329@547|Enterobacter	1236|Gammaproteobacteria	S	Belongs to the UPF0149 family	yecA	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
k59_18257_1	472759.Nhal_0882	4.42e-65	201.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1WYAR@135613|Chromatiales	135613|Chromatiales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_72537_1	1123250.KB908390_gene142	7.32e-29	119.0	COG3914@1|root,COG3914@2|Bacteria,1TT2Q@1239|Firmicutes,4H8WB@909932|Negativicutes	909932|Negativicutes	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
k59_111306_1	1047013.AQSP01000058_gene2026	5.58e-07	53.1	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
k59_95873_1	1168034.FH5T_13830	4.48e-37	139.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
k59_64875_1	1121468.AUBR01000044_gene1844	3.06e-12	63.9	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,42G80@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_64875_2	1165841.SULAR_07940	4.72e-71	216.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2YP4I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_64875_3	1165841.SULAR_07935	1.72e-47	162.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2YMUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_214625_1	1165841.SULAR_04572	8.9e-109	316.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2YQ46@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_90715_1	925409.KI911562_gene2749	1.13e-14	73.6	COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,1IXRU@117747|Sphingobacteriia	976|Bacteroidetes	S	Guanylyl transferase CofC like	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
k59_106077_1	395493.BegalDRAFT_3277	1.02e-70	230.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CZB,EAL,GAF_2,GGDEF,NMT1,PAS,PAS_3,PAS_9,Phosphonate-bd,SBP_bac_3
k59_206867_1	1165841.SULAR_08247	2.12e-82	274.0	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_222489_1	269084.syc2278_d	4.82e-25	112.0	COG0642@1|root,COG2199@1|root,COG5000@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,COG5000@2|Bacteria,1G13T@1117|Cyanobacteria,1H42E@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,Response_reg
k59_90718_1	243159.AFE_0746	1.27e-59	188.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,2NCRQ@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_137225_1	886377.Murru_3059	1.85e-68	214.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_137225_2	411154.GFO_0513	1.22e-06	49.7	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_75535_1	395493.BegalDRAFT_2558	5.09e-68	226.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,460CP@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_152672_1	313624.NSP_910	8.88e-101	309.0	COG0863@1|root,COG0863@2|Bacteria,1G1WV@1117|Cyanobacteria,1HRCG@1161|Nostocales	1117|Cyanobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_106080_1	2340.JV46_15460	3.31e-86	259.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,1RYZ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_59900_1	283699.D172_2441	5.09e-60	196.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,2PZIJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0382	AIRS,AIRS_C
k59_13401_1	340099.Teth39_0807	1.68e-29	119.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,42FD0@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_13401_2	96561.Dole_2792	7.84e-06	49.3	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2MHKD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_191513_1	1165841.SULAR_01963	1.22e-88	269.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2YNY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_191513_2	1165841.SULAR_01968	6.56e-79	240.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,43AMB@68525|delta/epsilon subdivisions,2YT1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_183842_1	1298865.H978DRAFT_2292	2.35e-20	95.9	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria,46979@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_21112_1	1355374.JARU01000013_gene66	1.43e-42	155.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_129681_2	1323663.AROI01000006_gene2828	1.41e-07	50.8	2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria	1224|Proteobacteria	S	TIGRFAM TIGR02449 family protein	VL23_04670	-	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	-
k59_245591_2	156889.Mmc1_1819	2.89e-39	140.0	COG3221@1|root,COG3221@2|Bacteria,1MX7I@1224|Proteobacteria	1224|Proteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_191521_1	2340.JV46_28080	1.97e-10	59.3	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1J4TT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_191521_2	493475.GARC_3963	4.23e-35	130.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,464XT@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_13405_1	1121015.N789_08390	9.32e-102	305.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RXZ5@1236|Gammaproteobacteria,1X4RH@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	rbcR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_183845_1	247490.KSU1_B0459	2.88e-12	67.8	COG0363@1|root,COG0363@2|Bacteria,2J0I5@203682|Planctomycetes	203682|Planctomycetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_183845_2	396588.Tgr7_0233	1.07e-11	64.7	COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria,1SGHM@1236|Gammaproteobacteria,1X2M7@135613|Chromatiales	135613|Chromatiales	NU	Type II secretion system (T2SS), protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
k59_59903_1	95619.PM1_0219430	1.68e-79	266.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	lhr	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
k59_168578_1	553385.JEMF01000003_gene2809	1.54e-59	199.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1XNYZ@135619|Oceanospirillales	135619|Oceanospirillales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_13410_1	631362.Thi970DRAFT_04046	0.000355	44.7	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1WWSN@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_21124_1	1165841.SULAR_03108	1.66e-09	57.4	COG0561@1|root,COG0561@2|Bacteria,1Q5G6@1224|Proteobacteria,42R7D@68525|delta/epsilon subdivisions,2YP2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_21124_2	1123070.KB899249_gene350	8.79e-85	269.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_145531_1	1328313.DS2_00015	1.29e-51	186.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,4661S@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_160499_1	1168034.FH5T_07860	8.21e-99	300.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,2FP2X@200643|Bacteroidia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_152684_1	1168034.FH5T_12060	2.19e-133	392.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,2FNB6@200643|Bacteroidia	976|Bacteroidetes	P	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_152689_1	1408444.JHYC01000058_gene1012	2.73e-59	195.0	COG3385@1|root,COG3385@2|Bacteria,1NIWM@1224|Proteobacteria,1S5FT@1236|Gammaproteobacteria,1JF06@118969|Legionellales	118969|Legionellales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_44480_1	1173029.JH980292_gene1949	1.8e-39	151.0	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1G3J0@1117|Cyanobacteria,1H9JS@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k59_98698_2	314607.KB13_1291	1.08e-12	67.4	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,1KPNY@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_52166_1	765910.MARPU_13715	6.26e-32	114.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,1WYK5@135613|Chromatiales	135613|Chromatiales	S	PFAM Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_52166_2	2340.JV46_24690	6.08e-111	325.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1J7ZS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	soxA	-	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_106115_1	1165841.SULAR_04267	1.56e-30	118.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_106115_2	387093.SUN_1137	1.16e-42	140.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_67870_1	7668.SPU_027267-tr	9.36e-68	232.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_5847_1	243233.MCA2390	3.16e-19	85.5	COG0682@1|root,COG0682@2|Bacteria,1MVRP@1224|Proteobacteria,1SDME@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
k59_5847_2	159087.Daro_0409	3.11e-58	192.0	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,2VPAH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k59_175902_1	402626.Rpic_4172	1.78e-13	73.2	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_175902_2	247634.GPB2148_1460	9.47e-09	55.1	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RQJX@1236|Gammaproteobacteria,1J8RS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k59_222523_1	247633.GP2143_10667	1.04e-23	101.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1J6FU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k59_13420_1	395493.BegalDRAFT_0114	3.53e-97	295.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,461W9@72273|Thiotrichales	72273|Thiotrichales	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_152692_1	1123279.ATUS01000001_gene1569	1.15e-81	268.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1J87N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	IV02_11925	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_191540_1	313596.RB2501_01880	9.59e-32	121.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia	976|Bacteroidetes	C	dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_191540_2	313596.RB2501_01885	4.73e-71	218.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1HY9T@117743|Flavobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_222530_1	1165841.SULAR_02393	4.07e-89	274.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2YMKD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_44491_1	395493.BegalDRAFT_1364	2.32e-25	109.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,45ZZC@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_152699_1	313596.RB2501_01011	1.44e-55	193.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_222531_1	349521.HCH_05230	1.35e-29	112.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,1S70H@1236|Gammaproteobacteria,1XKFQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Invasion gene expression up-regulator	-	-	-	-	-	-	-	-	-	-	-	-	SirB
k59_99111_2	946077.W5A_12876	7.91e-33	125.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1HX8A@117743|Flavobacteriia	976|Bacteroidetes	S	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
k59_130071_1	387093.SUN_1172	1.91e-89	269.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,42NM9@68525|delta/epsilon subdivisions,2YNQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_130071_2	1165841.SULAR_02608	1.5e-68	210.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2YN8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Molybdenum cofactor biosynthesis protein	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_207222_1	1165841.SULAR_08382	2.56e-166	483.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2YMJN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
k59_13697_1	395493.BegalDRAFT_1364	3.74e-66	221.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,45ZZC@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_153050_1	387093.SUN_0562	1.06e-32	120.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23
k59_13703_1	504472.Slin_1532	7.9e-73	232.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JXM@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_44813_1	1168034.FH5T_10075	2.48e-16	74.3	COG1438@1|root,COG1438@2|Bacteria,4NSSS@976|Bacteroidetes,2FR3Q@200643|Bacteroidia	976|Bacteroidetes	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
k59_44813_2	1168034.FH5T_10070	2.16e-63	199.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,2G07D@200643|Bacteroidia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_191888_2	489825.LYNGBM3L_40810	1.86e-35	130.0	COG0581@1|root,COG0581@2|Bacteria,1G1S1@1117|Cyanobacteria,1H8Y3@1150|Oscillatoriales	1117|Cyanobacteria	P	COG0581 ABC-type phosphate transport system permease component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_75947_1	143224.JQMD01000002_gene3309	3.09e-67	226.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_10,TPR_12,TPR_7,TPR_8
k59_176198_1	745014.OMB55_00021930	7.8e-85	279.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RS1Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_83326_1	187272.Mlg_1944	6.46e-64	214.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_122408_1	1042375.AFPL01000008_gene3243	2.32e-66	212.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,468IU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_230343_1	292415.Tbd_0873	6.75e-74	223.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,2W1W6@28216|Betaproteobacteria,1KSRH@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
k59_86567_1	1123401.JHYQ01000047_gene162	3.96e-77	235.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1S8DJ@1236|Gammaproteobacteria,463PP@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
k59_132910_1	1165841.SULAR_00905	3.77e-111	340.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_70972_1	2340.JV46_18500	8.12e-95	299.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J57P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k59_47884_1	1165841.SULAR_04207	8.9e-101	300.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2,CW_binding_1,DUF5011,PG_binding_1,YkuD
k59_47884_2	1165841.SULAR_04212	1.11e-10	62.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55621_1	395493.BegalDRAFT_0921	1.83e-63	214.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,45ZVK@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_132915_1	1168034.FH5T_09785	2.88e-37	133.0	COG1999@1|root,COG1999@2|Bacteria,4NU1J@976|Bacteroidetes,2FXFP@200643|Bacteroidia	976|Bacteroidetes	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_218138_1	2340.JV46_27820	2.4e-101	306.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1J4J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_218138_2	545264.KB898744_gene1949	5.84e-26	99.0	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,1SD0H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_47893_1	292415.Tbd_2658	1e-23	93.2	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2WC4Z@28216|Betaproteobacteria,1KT6F@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrC like protein	-	-	-	-	-	-	-	-	-	-	-	-	DsrC
k59_156113_1	1442598.JABW01000020_gene1960	1.94e-64	203.0	COG3677@1|root,COG3677@2|Bacteria,1RBA7@1224|Proteobacteria,4304X@68525|delta/epsilon subdivisions,2YRUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_218142_1	1165841.SULAR_08889	1e-93	275.0	2994D@1|root,2ZW7V@2|Bacteria,1Q2D1@1224|Proteobacteria,42VGB@68525|delta/epsilon subdivisions,2YQM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40244_1	1123296.JQKE01000011_gene249	1.72e-23	102.0	COG4916@1|root,COG4916@2|Bacteria,1MXWM@1224|Proteobacteria,2WEG3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
k59_210207_1	1049564.TevJSym_bc00380	4.08e-99	300.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1JBG6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	dgcB	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
k59_70983_1	3067.XP_002945838.1	2.06e-21	94.0	COG0696@1|root,KOG4513@2759|Eukaryota,37INC@33090|Viridiplantae,34JTN@3041|Chlorophyta	3041|Chlorophyta	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_1516_1	929562.Emtol_0629	4.58e-61	197.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_32656_1	349521.HCH_03070	1.82e-98	296.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1XIG5@135619|Oceanospirillales	135619|Oceanospirillales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86588_1	1216966.BAUC01000017_gene736	0.000111	49.3	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C peroxidase	yhjA	GO:0000302,GO:0003674,GO:0003824,GO:0004130,GO:0004601,GO:0005488,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009061,GO:0009636,GO:0009987,GO:0010035,GO:0015980,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0042221,GO:0042493,GO:0042542,GO:0042743,GO:0044237,GO:0045333,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
k59_132935_1	572480.Arnit_0212	9.1e-109	330.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM Alpha amylase, catalytic	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_163895_2	635013.TherJR_0119	0.000125	48.9	COG3391@1|root,COG3391@2|Bacteria,1UW22@1239|Firmicutes,24W73@186801|Clostridia,266DU@186807|Peptococcaceae	186801|Clostridia	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
k59_194828_1	994479.GL877882_gene6849	8.46e-08	56.6	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4EA6V@85010|Pseudonocardiales	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k59_47909_1	1121035.AUCH01000012_gene3022	2.17e-85	281.0	COG1352@1|root,COG5001@1|root,COG1352@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVWQ@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4
k59_163897_1	1168034.FH5T_16745	5.97e-87	263.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,2FM13@200643|Bacteroidia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_163897_2	1168034.FH5T_16750	8.22e-35	120.0	COG1366@1|root,COG1366@2|Bacteria,4NTAB@976|Bacteroidetes,2FYPE@200643|Bacteroidia	976|Bacteroidetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
k59_63321_1	160488.PP_1866	1.44e-105	320.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1YV8C@136845|Pseudomonas putida group	1236|Gammaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
k59_171714_1	1499967.BAYZ01000068_gene1962	5.21e-62	204.0	COG4972@1|root,COG4972@2|Bacteria,2NPF6@2323|unclassified Bacteria	2|Bacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_32670_1	398720.MED217_15515	9.81e-33	119.0	COG5642@1|root,COG5642@2|Bacteria,4NN76@976|Bacteroidetes,1I1NV@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
k59_63324_1	400668.Mmwyl1_2615	2.49e-41	150.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1XHZM@135619|Oceanospirillales	135619|Oceanospirillales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_225814_1	1392498.JQLH01000001_gene848	4.01e-92	272.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1HXHF@117743|Flavobacteriia,2PGAT@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_225814_2	1004149.AFOE01000042_gene2778	4.52e-05	44.3	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,1HXZA@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_156139_1	391587.KAOT1_21642	3.99e-43	142.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1I3ZI@117743|Flavobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_71003_1	1168034.FH5T_20685	1.52e-85	273.0	COG5640@1|root,COG5640@2|Bacteria,4PKEW@976|Bacteroidetes,2FRKU@200643|Bacteroidia	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
k59_55646_1	1168034.FH5T_01715	2.91e-100	305.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia	976|Bacteroidetes	E	Xaa-His dipeptidase	pepD_1	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1529_1	1443665.JACA01000006_gene66	5.82e-07	57.4	COG2972@1|root,COG2972@2|Bacteria,4NMNB@976|Bacteroidetes,1I1WI@117743|Flavobacteriia,2YGPK@290174|Aquimarina	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_32679_1	313596.RB2501_04470	1.08e-34	122.0	COG4103@1|root,COG4103@2|Bacteria,4NWM3@976|Bacteroidetes,1I5QJ@117743|Flavobacteriia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_179471_1	1117318.PRUB_00230	1.79e-07	54.3	COG1776@1|root,COG2204@1|root,COG1776@2|Bacteria,COG2204@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,2PZSU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG0784 FOG CheY-like receiver	cheC	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_179471_2	658086.HMPREF0994_04296	9.07e-28	119.0	COG2972@1|root,COG2972@2|Bacteria,1TRD8@1239|Firmicutes,24BXA@186801|Clostridia,27RV8@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
k59_132957_1	1165841.SULAR_07198	8.65e-77	241.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2YMAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycolate oxidase subunit	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_132957_2	1165841.SULAR_07203	5.28e-33	122.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2YMVQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ribonuclease BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_210230_1	1168034.FH5T_07080	1.55e-151	444.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,2FKZS@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_17345_1	1120968.AUBX01000013_gene3474	9.19e-09	57.8	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,47KKI@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_17345_2	1094508.Tsac_1866	6.97e-18	77.8	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,24QIM@186801|Clostridia,42GUT@68295|Thermoanaerobacterales	186801|Clostridia	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k59_87016_1	2340.JV46_19230	1.79e-26	112.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1J58Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_87016_2	479432.Sros_6505	1.99e-15	77.8	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria,4EQQX@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_172186_1	1168034.FH5T_12915	1.43e-195	550.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_148817_1	1408473.JHXO01000004_gene180	4.02e-17	79.0	28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,2FY4J@200643|Bacteroidia	976|Bacteroidetes	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
k59_148817_2	240016.ABIZ01000001_gene807	1.48e-07	57.0	2DW1W@1|root,33Y5Q@2|Bacteria,46VIP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_148817_3	1168034.FH5T_04825	3.47e-49	169.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia	976|Bacteroidetes	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_48417_1	1123070.KB899249_gene350	1.39e-178	516.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_48417_2	1500259.JQLD01000008_gene1985	3.66e-21	86.7	COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,2U1SQ@28211|Alphaproteobacteria,4BAX2@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_33230_1	1165841.SULAR_04182	2.49e-70	214.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,42V9F@68525|delta/epsilon subdivisions,2YQRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_33230_2	1165841.SULAR_04187	8.55e-37	127.0	COG4807@1|root,COG4807@2|Bacteria,1N991@1224|Proteobacteria,43BD5@68525|delta/epsilon subdivisions,2YQNH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1456)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
k59_25146_1	1165841.SULAR_01310	4.53e-74	233.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YQ1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_125807_1	765913.ThidrDRAFT_2299	4.39e-65	223.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WXAA@135613|Chromatiales	135613|Chromatiales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_40729_1	563040.Saut_1715	1.07e-42	147.0	COG0745@1|root,COG0745@2|Bacteria,1Q6G8@1224|Proteobacteria,42T3T@68525|delta/epsilon subdivisions,2YPQK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_9851_1	1408473.JHXO01000001_gene2411	1.38e-117	342.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel family protein	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_133399_1	1254432.SCE1572_00310	7.91e-39	150.0	COG0402@1|root,COG2374@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria,2YUGP@29|Myxococcales	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,DUF4215,LTD,TSP_3
k59_125819_1	519989.ECTPHS_03197	1.07e-98	310.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales	135613|Chromatiales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_25162_1	247490.KSU1_C0452	4.46e-33	133.0	COG1629@1|root,COG4771@2|Bacteria,2J2B7@203682|Planctomycetes	203682|Planctomycetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_40733_1	1121904.ARBP01000005_gene4823	8.77e-34	126.0	28MAS@1|root,2ZAPE@2|Bacteria,4NJ31@976|Bacteroidetes,47TP8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
k59_187621_1	641526.ADIWIN_1973	2.72e-57	196.0	COG3119@1|root,COG3119@2|Bacteria,4NETT@976|Bacteroidetes,1HX4V@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_144197_1	2340.JV46_29080	3.73e-115	346.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1J4EF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1519 3-deoxy-D-manno-octulosonic-acid transferase	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
k59_190455_1	1165841.SULAR_00340	1.12e-130	379.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_182743_1	616991.JPOO01000003_gene18	1.93e-80	247.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1HYUA@117743|Flavobacteriia,23H44@178469|Arenibacter	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_97642_1	1121937.AUHJ01000005_gene2214	6.75e-58	192.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0456 Acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_144203_1	391587.KAOT1_20017	3.96e-75	234.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HXDJ@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
k59_236941_2	935948.KE386495_gene1099	2.06e-14	70.1	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,42GW8@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_58810_1	1297742.A176_02101	6.52e-10	64.7	COG0515@1|root,COG0515@2|Bacteria,1PEIZ@1224|Proteobacteria,433VS@68525|delta/epsilon subdivisions,2X3Q2@28221|Deltaproteobacteria,2YWTJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PDZ_2,Pkinase
k59_66651_1	573413.Spirs_2764	9.19e-73	232.0	COG4948@1|root,COG4948@2|Bacteria,2J7EX@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k59_167448_1	1168034.FH5T_06020	4.08e-82	258.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes,2FW0F@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
k59_35939_1	1123368.AUIS01000003_gene1816	8.53e-41	143.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,2NBV2@225057|Acidithiobacillales	1236|Gammaproteobacteria	O	Peptidase family M48	htpX	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_89714_1	85643.Tmz1t_2792	2.33e-25	106.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KUIC@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
k59_128709_1	1168034.FH5T_09865	8.38e-83	253.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,2FPBF@200643|Bacteroidia	976|Bacteroidetes	S	TIGR00255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_89715_1	118005.AWNK01000005_gene1671	1.27e-09	63.9	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K18563	ko00332,ko01130,map00332,map01130	-	R10737	RC03265	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
k59_190483_1	335543.Sfum_1622	2.08e-47	173.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C554
k59_167465_1	114615.BRADO6238	7.76e-92	301.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,3JSNT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_4957_1	882378.RBRH_03139	1.82e-06	51.6	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria,1K1E7@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_4957_2	1123073.KB899241_gene2999	2.96e-58	185.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,1T1KA@1236|Gammaproteobacteria,1X38R@135614|Xanthomonadales	135614|Xanthomonadales	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_89724_1	1396141.BATP01000007_gene5608	1.35e-18	84.3	COG0745@1|root,COG0745@2|Bacteria,46UVZ@74201|Verrucomicrobia,2IVDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_229006_1	1049564.TevJSym_at00260	1.37e-100	306.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1J4GC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_3895,iJN746.PP_5056	Metalloenzyme,Phosphodiest,iPGM_N
k59_182773_1	1120966.AUBU01000008_gene2383	1.21e-17	91.7	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_19958_1	1121927.GOHSU_12_00470	1.1e-10	74.3	COG0515@1|root,COG5184@1|root,COG0515@2|Bacteria,COG5184@2|Bacteria,2IG31@201174|Actinobacteria,4GCNZ@85026|Gordoniaceae	201174|Actinobacteria	DKLTZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Flg_new,Pkinase,RCC1,RCC1_2
k59_58814_1	1168034.FH5T_05740	5.79e-92	295.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,2FN0V@200643|Bacteroidia	976|Bacteroidetes	G	Glycoside hydrolase family 3	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_151623_1	511.JT27_20035	2.1e-83	258.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2VM0Z@28216|Betaproteobacteria,3T6CK@506|Alcaligenaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_159436_1	525897.Dbac_2288	3.94e-100	306.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria,2M8IR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_167475_1	2340.JV46_07560	1.94e-83	256.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1J5KW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	yhdH	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0043957,GO:0055114	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_28001_1	997829.HMPREF1121_00696	1.38e-92	284.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,2FNHU@200643|Bacteroidia,22XBJ@171551|Porphyromonadaceae	976|Bacteroidetes	E	LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_175111_2	1250232.JQNJ01000001_gene775	3.02e-09	53.5	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1I3WW@117743|Flavobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_183116_1	1168034.FH5T_04775	6.3e-117	344.0	COG0436@1|root,COG0436@2|Bacteria,4NFWS@976|Bacteroidetes,2FMMU@200643|Bacteroidia	976|Bacteroidetes	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_59206_1	1168034.FH5T_10550	6.17e-62	195.0	COG0546@1|root,COG0546@2|Bacteria,4NMPP@976|Bacteroidetes,2FS95@200643|Bacteroidia	976|Bacteroidetes	S	HAD hydrolase, family IA, variant	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_152062_1	1441930.Z042_21960	6.76e-25	98.6	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,401GX@613|Serratia	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF882)	ycbK	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
k59_152062_2	631362.Thi970DRAFT_04866	7.42e-87	278.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1WXK8@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_12693_1	1499967.BAYZ01000182_gene4433	1.87e-09	60.1	297CM@1|root,2ZUK5@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
k59_237310_1	1168034.FH5T_10910	1.77e-111	331.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,2FMTV@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_20287_1	497964.CfE428DRAFT_0593	1.53e-49	171.0	COG3666@1|root,COG3666@2|Bacteria,46S8M@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_175116_1	2340.JV46_03300	9.44e-93	278.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,1J5RQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yedI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_51435_1	1300345.LF41_505	0.000125	43.5	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1SKNI@1236|Gammaproteobacteria,1X5G2@135614|Xanthomonadales	135614|Xanthomonadales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_51435_2	1293048.CBMB010000004_gene2186	1.2e-39	137.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_51435_3	743299.Acife_1209	3.46e-20	91.7	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,2NCSK@225057|Acidithiobacillales	225057|Acidithiobacillales	Q	Prolyl oligopeptidase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH,Peptidase_S9
k59_74761_1	32049.SYNPCC7002_A0819	8.41e-07	48.9	COG1569@1|root,COG1569@2|Bacteria,1G7ZZ@1117|Cyanobacteria,1H17D@1129|Synechococcus	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_229257_1	547144.HydHO_0404	7.68e-15	80.1	COG1337@1|root,COG1337@2|Bacteria	2|Bacteria	L	defense response to virus	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
k59_12697_1	1121930.AQXG01000005_gene709	1.86e-15	84.7	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
k59_67168_1	768671.ThimaDRAFT_0609	1.04e-68	213.0	2BZD1@1|root,32XYD@2|Bacteria,1N516@1224|Proteobacteria,1S961@1236|Gammaproteobacteria,1X1EP@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67168_2	768671.ThimaDRAFT_0610	6.7e-41	136.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k59_59218_1	4155.Migut.D01328.1.p	1.66e-55	175.0	COG0096@1|root,KOG1754@2759|Eukaryota,37UMN@33090|Viridiplantae,3GIWP@35493|Streptophyta,44TEK@71274|asterids	35493|Streptophyta	J	Ribosomal protein S8	rps8	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14,Ribosomal_L16,Ribosomal_S8
k59_59218_2	3649.evm.model.supercontig_0.195	3.65e-52	169.0	COG0093@1|root,COG0197@1|root,KOG0901@2759|Eukaryota,KOG3422@2759|Eukaryota,383TF@33090|Viridiplantae,3GWN0@35493|Streptophyta,3I06C@3699|Brassicales	35493|Streptophyta	J	Ribosomal protein L16p/L10e	-	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14,Ribosomal_L16
k59_144829_1	395493.BegalDRAFT_2299	9.34e-144	418.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_237316_1	388413.ALPR1_11965	2.46e-106	328.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47TP1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_36279_1	1278073.MYSTI_04285	1.14e-75	240.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,42MA1@68525|delta/epsilon subdivisions,2WPWQ@28221|Deltaproteobacteria,2Z1GV@29|Myxococcales	28221|Deltaproteobacteria	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_74763_1	72658.Bostr.21524s0001.1.p	7.47e-55	173.0	COG1007@1|root,KOG4668@2759|Eukaryota,37WKT@33090|Viridiplantae,3GKHT@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_198805_1	1049564.TevJSym_ap00690	5.01e-104	305.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1J4TW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_198805_2	283942.IL0975	5.19e-07	50.8	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,2QFEQ@267893|Idiomarinaceae	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_20294_1	1168034.FH5T_08365	1.85e-136	392.0	2BVTQ@1|root,2Z7J9@2|Bacteria,4NGSY@976|Bacteroidetes,2FWJ5@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k59_152076_1	1168034.FH5T_19090	2.05e-118	362.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,2FMCP@200643|Bacteroidia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_144831_1	1168034.FH5T_05140	7.14e-95	282.0	COG4912@1|root,COG4912@2|Bacteria,4NUAZ@976|Bacteroidetes,2FQ8F@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_74764_1	313596.RB2501_05935	2.06e-34	120.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k59_74764_2	886377.Murru_1467	5.98e-58	180.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
k59_98013_1	1165841.SULAR_05483	4.84e-134	396.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_144834_1	1168034.FH5T_19455	2.48e-46	168.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_183138_1	314285.KT71_08620	5.97e-151	433.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1J9WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_67172_1	370438.PTH_0149	7.87e-33	132.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,261KM@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_51445_1	2340.JV46_25130	4.64e-114	338.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1J5VQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_98015_1	870187.Thini_4336	3.63e-94	296.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RS9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_214008_1	1384054.N790_07215	5.68e-39	146.0	COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,1X4T5@135614|Xanthomonadales	135614|Xanthomonadales	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
k59_5262_1	1165841.SULAR_02698	1.06e-85	273.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2YRC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_74777_1	395493.BegalDRAFT_3004	1.87e-62	197.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,460X4@72273|Thiotrichales	72273|Thiotrichales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_240095_2	387093.SUN_1686	5.74e-29	105.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria	1224|Proteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_2
k59_292_1	1541065.JRFE01000058_gene5625	2.85e-06	58.5	COG0749@1|root,COG0749@2|Bacteria,1G4PE@1117|Cyanobacteria,3VM16@52604|Pleurocapsales	1117|Cyanobacteria	L	DNA polymerase A domain	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
k59_62177_1	1187848.AJYQ01000003_gene410	1.99e-123	365.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_8025_1	1168034.FH5T_10390	5.19e-111	333.0	COG1538@1|root,COG1538@2|Bacteria,4NGIX@976|Bacteroidetes,2FM9H@200643|Bacteroidia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_8026_1	1121861.KB899951_gene2303	8.03e-29	120.0	COG3209@1|root,COG3209@2|Bacteria,1PHC1@1224|Proteobacteria,2V8X0@28211|Alphaproteobacteria,2JXWU@204441|Rhodospirillales	204441|Rhodospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_131825_1	395493.BegalDRAFT_1778	3.15e-39	143.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,460WJ@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM DNA polymerase III, delta	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k59_108612_2	1499967.BAYZ01000026_gene1637	6.08e-34	123.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	marR9	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
k59_8030_1	95619.PM1_0209255	1.49e-24	101.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_178238_1	1121937.AUHJ01000005_gene2293	1.94e-68	214.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,464V9@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
k59_178238_2	305700.B447_16874	1.32e-18	84.0	COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,2VN5U@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_224650_1	1173022.Cri9333_0384	9.73e-68	207.0	COG3865@1|root,COG3865@2|Bacteria,1G38J@1117|Cyanobacteria,1H8CW@1150|Oscillatoriales	1117|Cyanobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
k59_224650_2	930169.B5T_01273	4.65e-36	128.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1S04F@1236|Gammaproteobacteria,1XP23@135619|Oceanospirillales	135619|Oceanospirillales	J	Metallopeptidase family M24	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_8032_1	247490.KSU1_B0387	2.73e-56	194.0	COG1109@1|root,COG1109@2|Bacteria,2IXRS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_8032_2	1054217.TALC_01288	1.16e-34	135.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT5C@28890|Euryarchaeota,241N2@183967|Thermoplasmata	183967|Thermoplasmata	C	FAD binding domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_77597_1	1168034.FH5T_11365	1.63e-43	146.0	2AISX@1|root,3199U@2|Bacteria,4NQ7A@976|Bacteroidetes,2FVPS@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_240116_1	1165841.SULAR_05623	2.02e-104	306.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2YMS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the TtcA family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_62182_1	1165841.SULAR_05438	1.37e-109	326.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_54457_1	765698.Mesci_0534	8.08e-56	182.0	29CEM@1|root,2ZZD2@2|Bacteria,1RE7K@1224|Proteobacteria,2U91P@28211|Alphaproteobacteria,43JT0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_209178_1	1168034.FH5T_21830	1.38e-163	465.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_131838_2	709991.Odosp_2756	1.84e-19	88.6	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,2FNAU@200643|Bacteroidia,22W8Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Penicillin-binding Protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_93212_2	1250232.JQNJ01000001_gene2994	2.74e-108	327.0	COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes,1HXAS@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
k59_139642_1	1121875.KB907551_gene1147	1.41e-36	129.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,1I26T@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	paiA	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_139642_2	1443665.JACA01000026_gene3613	3.04e-13	70.1	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,1HYBE@117743|Flavobacteriia,2YHKK@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_155043_1	1122599.AUGR01000010_gene950	9.21e-39	145.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1XKC6@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_216967_1	1165841.SULAR_09699	1.03e-129	377.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_224663_1	1121937.AUHJ01000011_gene2959	4.13e-130	380.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,46537@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iSF_1195.SF3294	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_209185_1	768706.Desor_2211	2e-15	77.8	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,26128@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_312_1	3880.AES87793	1.94e-34	128.0	COG0090@1|root,COG0185@1|root,KOG0438@2759|Eukaryota,KOG0899@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,4JTF7@91835|fabids	35493|Streptophyta	J	50S ribosomal protein	rpl2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C,Ribosomal_S19
k59_312_2	4081.Solyc01g007610.2.1	7.34e-66	211.0	COG0091@1|root,KOG1711@2759|Eukaryota,3842X@33090|Viridiplantae,3GW7N@35493|Streptophyta,44TSR@71274|asterids	35493|Streptophyta	J	Ribosomal protein L22p/L17e	-	GO:0000313,GO:0000315,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_312_3	3983.cassava4.1_020914m	9.11e-132	376.0	COG0092@1|root,2QV63@2759|Eukaryota,37ITR@33090|Viridiplantae,3GH7T@35493|Streptophyta,4JSQ4@91835|fabids	35493|Streptophyta	J	Belongs to the universal ribosomal protein uS3 family	rps3	GO:0002181,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3_C
k59_216976_1	1168034.FH5T_10695	3.02e-145	419.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FNZ2@200643|Bacteroidia	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_54830_1	1004149.AFOE01000004_gene2287	1.72e-40	149.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,1HZGP@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Fucosidase_C
k59_23781_1	317025.Tcr_0033	1.35e-103	310.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RYYZ@1236|Gammaproteobacteria,461TG@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
k59_178623_2	1165841.SULAR_00480	3.92e-43	149.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2YMYR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_224968_1	1122604.JONR01000006_gene2641	5.87e-10	66.2	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1X4TB@135614|Xanthomonadales	135614|Xanthomonadales	M	(Lipo)protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_16040_1	1236959.BAMT01000006_gene438	2.59e-106	318.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,2KM6F@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_47056_1	880073.Calab_3335	5.21e-43	150.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
k59_47058_1	323261.Noc_0717	3.14e-70	222.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1WXGI@135613|Chromatiales	135613|Chromatiales	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	SPOR,YkuD
k59_93550_1	714943.Mucpa_4717	2.76e-31	116.0	COG3335@1|root,COG3335@2|Bacteria,4PNWI@976|Bacteroidetes,1IZ7Q@117747|Sphingobacteriia	976|Bacteroidetes	L	SPTR Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_93550_2	1283300.ATXB01000001_gene2341	9.02e-69	214.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_139977_1	243231.GSU2262	3.84e-73	231.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	gnnB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2351	DegT_DnrJ_EryC1
k59_101184_1	396588.Tgr7_3083	1.88e-62	199.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1SZ87@1236|Gammaproteobacteria,1X2J8@135613|Chromatiales	135613|Chromatiales	P	PFAM ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_101184_2	1123514.KB905899_gene1360	2.12e-94	281.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1RR9A@1236|Gammaproteobacteria,46233@72273|Thiotrichales	72273|Thiotrichales	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
k59_85733_1	414684.RC1_2722	0.000688	48.5	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TQU3@28211|Alphaproteobacteria,2JQSX@204441|Rhodospirillales	204441|Rhodospirillales	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9
k59_108914_1	313596.RB2501_09980	1.48e-79	239.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1HWWF@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_39343_2	930166.CD58_27060	1.95e-11	66.6	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
k59_224973_1	1165841.SULAR_04507	7.64e-100	297.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2YQN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_201751_1	1163617.SCD_n00406	4.34e-28	111.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_201751_2	1049564.TevJSym_bd00190	9.02e-44	149.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1JBV7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulatory protein, C terminal	ompR	GO:0000156,GO:0000160,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0035556,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_186328_1	384765.SIAM614_02581	1.19e-84	267.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_139987_2	1397528.Q671_14960	3.4e-37	138.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales	135619|Oceanospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_240389_1	160488.PP_5105	2.88e-19	80.9	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1SGCU@1236|Gammaproteobacteria,1YVN2@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_240389_2	105559.Nwat_1991	1.08e-35	129.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales	135613|Chromatiales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_209473_1	2340.JV46_17600	4.5e-35	127.0	COG3151@1|root,COG3151@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1249)	yqiB	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
k59_201755_1	314230.DSM3645_05675	1.22e-115	337.0	COG0657@1|root,COG0657@2|Bacteria,2IWRZ@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
k59_186330_1	1168034.FH5T_07085	1.1e-09	58.9	28UTG@1|root,2ZGXN@2|Bacteria,4P80G@976|Bacteroidetes,2FZFM@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_170859_1	272943.RSP_3134	7.3e-06	52.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,2TS3G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_116711_1	702450.CUW_1472	8.85e-40	147.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,3VP0U@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_201757_1	395493.BegalDRAFT_0599	1.23e-84	261.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,461WN@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_108928_1	1446473.JHWH01000008_gene182	3.78e-51	175.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2PW5X@265|Paracoccus	28211|Alphaproteobacteria	P	TOBE domain	-	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
k59_155393_1	1168034.FH5T_17425	1.18e-110	328.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_108931_1	566466.NOR53_2312	4.84e-91	272.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_31686_1	864565.HMPREF0379_0586	1.53e-09	63.5	COG4249@1|root,COG4249@2|Bacteria,1V3F2@1239|Firmicutes,24G71@186801|Clostridia	186801|Clostridia	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
k59_16057_1	929558.SMGD1_1263	3.28e-44	152.0	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_155395_1	1250232.JQNJ01000001_gene523	1.47e-51	181.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,1I0M4@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_201758_1	749222.Nitsa_0522	9e-38	134.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2YNTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_26519_1	1121939.L861_13700	3.75e-42	149.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RXV9@1236|Gammaproteobacteria,1XJQN@135619|Oceanospirillales	135619|Oceanospirillales	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_N,GST_N_3
k59_57436_1	927658.AJUM01000040_gene855	1.15e-54	179.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia,3XIK5@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein L6	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_18570_1	1121920.AUAU01000003_gene1181	4.4e-13	68.2	COG0515@1|root,COG0515@2|Bacteria,3Y6PF@57723|Acidobacteria	57723|Acidobacteria	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_142722_1	378806.STAUR_4928	5.1e-08	54.7	COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria,1N0QS@1224|Proteobacteria	1224|Proteobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADC,Amino_oxidase,NAD_binding_8
k59_142722_2	1121904.ARBP01000006_gene3776	2.86e-13	72.8	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,Reg_prop,SpoIIE,Y_Y_Y
k59_127246_1	1411123.JQNH01000001_gene1854	3.09e-47	175.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
k59_196968_1	1215092.PA6_009_00300	4.23e-50	172.0	28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P22 coat protein-protein 5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57439_1	387093.SUN_0560	1.5e-06	55.1	COG5049@1|root,COG5049@2|Bacteria,1PFK8@1224|Proteobacteria,42YJI@68525|delta/epsilon subdivisions,2YRCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ADL	5'-3' exoribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34520_1	930166.CD58_02790	5.68e-26	110.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_173563_1	589873.EP13_03470	3.06e-33	130.0	COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,46595@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
k59_103806_1	768706.Desor_2594	1.64e-64	199.0	COG3576@1|root,COG3576@2|Bacteria,1V4U5@1239|Firmicutes,24SBM@186801|Clostridia,262YF@186807|Peptococcaceae	186801|Clostridia	S	PFAM pyridoxamine 5'-phosphate	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_111772_2	1392488.JHZY01000004_gene2718	6.4e-66	210.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1HYA2@117743|Flavobacteriia,2XK60@283735|Leeuwenhoekiella	976|Bacteroidetes	EG	EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_196969_2	743720.Psefu_3451	7.42e-31	113.0	COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1YYUR@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1820)	IV02_29925	-	-	-	-	-	-	-	-	-	-	-	DUF1820
k59_189042_1	1165841.SULAR_03078	2.03e-76	229.0	2BMN0@1|root,32G77@2|Bacteria,1Q0X8@1224|Proteobacteria,42SM0@68525|delta/epsilon subdivisions,2YPGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111786_1	1165841.SULAR_06158	4.41e-108	321.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_65228_1	1265313.HRUBRA_02687	2.67e-08	53.9	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_227637_1	2754.EH55_02555	1.13e-27	117.0	COG0553@1|root,COG0553@2|Bacteria,3TANN@508458|Synergistetes	508458|Synergistetes	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
k59_243172_1	1408473.JHXO01000010_gene3598	2.85e-37	140.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,2FNIX@200643|Bacteroidia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_26541_1	870187.Thini_0271	2.22e-27	107.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,460PT@72273|Thiotrichales	72273|Thiotrichales	P	Eukaryotic-type carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_57728_1	1165841.SULAR_02583	7.37e-88	273.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_220425_1	391587.KAOT1_01579	1.42e-118	360.0	COG1505@1|root,COG1505@2|Bacteria,4NM0V@976|Bacteroidetes,1I0XU@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_112116_1	478801.Ksed_07840	1.83e-55	184.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,1ZVHJ@145357|Dermacoccaceae	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_189351_1	879212.DespoDRAFT_01980	4.99e-21	92.0	COG1230@1|root,COG2259@1|root,COG1230@2|Bacteria,COG2259@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WMDZ@28221|Deltaproteobacteria,2MIR0@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
k59_189351_2	1121405.dsmv_3550	4.84e-48	157.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQGJ@28221|Deltaproteobacteria,2MKF4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_197270_1	317025.Tcr_1590	1.38e-73	248.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_73230_1	340177.Cag_1600	1.72e-15	75.1	COG3950@1|root,COG3950@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
k59_73230_2	101510.RHA1_ro11152	4.02e-53	181.0	COG0732@1|root,COG0732@2|Bacteria,2ICQT@201174|Actinobacteria,4G3F0@85025|Nocardiaceae	201174|Actinobacteria	V	PFAM restriction modification system DNA specificity domain-containing protein	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_3899_1	1173024.KI912151_gene2447	1.07e-43	164.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_189355_1	1167006.UWK_02874	7.28e-28	121.0	COG0784@1|root,COG0834@1|root,COG4191@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_212601_2	1349785.BAUG01000135_gene2872	7.97e-76	233.0	COG3335@1|root,COG3335@2|Bacteria,4NR21@976|Bacteroidetes,1I35Q@117743|Flavobacteriia	976|Bacteroidetes	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_235884_2	1165841.SULAR_00375	1.23e-64	200.0	COG0235@1|root,COG0235@2|Bacteria,1N84G@1224|Proteobacteria,42RVW@68525|delta/epsilon subdivisions,2YP4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k59_197271_2	573063.Metin_1240	1.18e-24	108.0	COG0618@1|root,arCOG01566@2157|Archaea,2XT9H@28890|Euryarchaeota,23Q6S@183939|Methanococci	183939|Methanococci	S	phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1,TrkA_N
k59_3900_1	1484157.PSNIH2_17235	5.62e-100	307.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,3VZZD@53335|Pantoea	1236|Gammaproteobacteria	T	GTP-binding protein TypA	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_11467_1	65093.PCC7418_3630	3.72e-12	62.8	2E9VI@1|root,3341D@2|Bacteria,1GRB3@1117|Cyanobacteria	1117|Cyanobacteria	S	Addiction module component, TIGR02574 family	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
k59_73248_1	1249627.D779_0468	3.84e-78	259.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WXAA@135613|Chromatiales	135613|Chromatiales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_119862_1	2340.JV46_11610	3.75e-61	190.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1JBM2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
k59_119862_2	2340.JV46_11590	1.4e-45	157.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1J4SR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host	djlA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_112142_1	1165841.SULAR_05478	6.33e-58	182.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42R6H@68525|delta/epsilon subdivisions,2YP0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_112142_2	1165841.SULAR_05473	2.92e-37	134.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2YME5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_143113_1	1165841.SULAR_04818	1.28e-50	172.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_143113_2	387093.SUN_1568	4.18e-35	123.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_143113_3	1165841.SULAR_04808	2.14e-21	90.1	2ENG1@1|root,33G3G@2|Bacteria,1NPIZ@1224|Proteobacteria,42ZV2@68525|delta/epsilon subdivisions,2YRT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212606_1	572477.Alvin_0186	4.43e-10	63.9	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales	135613|Chromatiales	CI	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_212606_2	1198232.CYCME_1869	2.63e-57	188.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,460AC@72273|Thiotrichales	72273|Thiotrichales	C	decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_73261_1	742767.HMPREF9456_01507	1.55e-21	94.7	COG5000@1|root,COG5000@2|Bacteria,4NFQN@976|Bacteroidetes,2FQJW@200643|Bacteroidia,22Z6G@171551|Porphyromonadaceae	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_8
k59_50015_1	215803.DB30_8592	4.46e-54	193.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,43BZC@68525|delta/epsilon subdivisions,2X7A3@28221|Deltaproteobacteria,2YWPR@29|Myxococcales	28221|Deltaproteobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt
k59_204819_1	469595.CSAG_03355	1.26e-37	145.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,3WWBT@544|Citrobacter	1236|Gammaproteobacteria	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
k59_42419_1	330214.NIDE0728	9.53e-10	61.2	COG1309@1|root,COG1309@2|Bacteria,3J1CN@40117|Nitrospirae	40117|Nitrospirae	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_42419_2	1408254.T458_23150	1.05e-05	47.8	COG5000@1|root,COG5000@2|Bacteria,1V3DV@1239|Firmicutes,4HGCX@91061|Bacilli,274DD@186822|Paenibacillaceae	91061|Bacilli	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_73267_1	1165841.SULAR_08909	1.54e-08	54.7	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_73267_2	1165841.SULAR_08914	1.54e-67	213.0	COG3301@1|root,COG3301@2|Bacteria,1QSRQ@1224|Proteobacteria,42PAY@68525|delta/epsilon subdivisions,2YN5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_112156_1	1168034.FH5T_12370	4.2e-98	292.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	1.1.1.133	ko:K00067,ko:K03810	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_235894_1	1168034.FH5T_00795	1.03e-24	104.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_143132_1	575540.Isop_1073	6.77e-06	53.9	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2J3AX@203682|Planctomycetes	2|Bacteria	O	COGs COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease	prcA	-	3.4.21.121	ko:K13735,ko:K20276,ko:K20755,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	B_lectin,Calx-beta,P_proprotein,Peptidase_S8
k59_104179_1	32057.KB217478_gene7553	1.1e-71	236.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1HJE5@1161|Nostocales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_18915_1	394503.Ccel_0864	3.59e-43	160.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	ko:K13611,ko:K13614	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_34841_1	395493.BegalDRAFT_2737	1.28e-35	127.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,461G2@72273|Thiotrichales	72273|Thiotrichales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k59_88793_2	1499967.BAYZ01000061_gene5966	2.12e-71	239.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	wspE	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3,2.7.7.65	ko:K03407,ko:K11444,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_220475_1	395493.BegalDRAFT_0272	3.02e-38	135.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,4600Q@72273|Thiotrichales	72273|Thiotrichales	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_220475_2	1283300.ATXB01000001_gene656	0.00024	43.1	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,1T3G5@1236|Gammaproteobacteria,1XH18@135618|Methylococcales	135618|Methylococcales	T	Domain of unknown function (DUF3329)	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA
k59_42438_2	1123487.KB892865_gene1375	7.83e-68	218.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria,2KZJK@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
k59_96585_1	1165841.SULAR_07315	2.22e-129	371.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_206835_1	1136177.KCA1_1151	1.19e-14	82.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae	91061|Bacilli	V	domain protein	XK27_06930	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
k59_98642_1	1049564.TevJSym_am00280	7.95e-36	140.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1J5BI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_82918_1	395493.BegalDRAFT_0680	1.34e-22	99.4	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,4616X@72273|Thiotrichales	72273|Thiotrichales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_59873_1	1165841.SULAR_10069	2.54e-102	302.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,42TVJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iJN746.PP_0110,iSFxv_1172.SFxv_0410	UbiA
k59_222455_1	330084.JNYZ01000003_gene2353	1.59e-40	147.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4DXH9@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32,HTH_33
k59_59878_1	1165841.SULAR_09589	4.35e-124	363.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,42PQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477	ATP-grasp
k59_175844_1	10224.XP_006819135.1	4.96e-55	199.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_44415_1	317025.Tcr_1393	3.24e-39	140.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,45ZQT@72273|Thiotrichales	72273|Thiotrichales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_28952_1	1047013.AQSP01000133_gene2156	1e-138	414.0	COG0445@1|root,COG0445@2|Bacteria,2NNXQ@2323|unclassified Bacteria	2|Bacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_13361_1	1267535.KB906767_gene998	1.85e-06	58.5	COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07680	ko02020,ko02024,map02020,map02024	M00476	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	FHA,GAF,GAF_2,GAF_3,HAMP,HATPase_c_2,SpoIIE
k59_183811_1	2340.JV46_06000	5.95e-48	161.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1J6DD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2863 Cytochrome c553	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_160450_1	598467.BrE312_3420	2.79e-06	54.3	COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,1RZ11@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC transporter	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_13362_1	622637.KE124774_gene3025	4.67e-30	119.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,36XR8@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Cobaltochelatase CobS subunit N terminal	cobS	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C,CobS_N
k59_145497_1	1121459.AQXE01000019_gene1898	9.05e-72	230.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria,2M8PV@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_191490_1	398767.Glov_1587	1.49e-65	227.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
k59_168546_1	1165841.SULAR_05983	4.45e-110	321.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2YNEP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_229933_1	1229205.BUPH_00803	9.39e-20	87.4	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VME6@28216|Betaproteobacteria,1K3H4@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_229933_2	98439.AJLL01000091_gene191	9.52e-31	112.0	COG3251@1|root,COG3251@2|Bacteria	2|Bacteria	P	PFAM MbtH domain protein	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	CBF_beta,MbtH
k59_237909_1	67257.JODR01000007_gene3922	1.46e-42	144.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
k59_106070_1	631362.Thi970DRAFT_03839	6.82e-07	49.7	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,1WYUF@135613|Chromatiales	135613|Chromatiales	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
k59_130007_2	238854.Q5GQL6_BPSYP	1.14e-30	120.0	4QB2Z@10239|Viruses,4QWQN@35237|dsDNA viruses  no RNA stage,4QPYN@28883|Caudovirales	28883|Caudovirales	S	gp45 sliding clamp, C terminal	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_75857_1	179408.Osc7112_1555	7.06e-67	227.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
k59_68129_1	1165841.SULAR_02923	2.13e-64	214.0	COG0068@1|root,COG0068@2|Bacteria,1NS2D@1224|Proteobacteria,42RUP@68525|delta/epsilon subdivisions,2YP7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hydE	-	-	-	-	-	-	-	-	-	-	-	-
k59_184127_2	381666.H16_A3215	5.96e-31	117.0	2C8C4@1|root,34B8I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_145886_1	1239962.C943_04390	1.61e-27	109.0	COG4461@1|root,COG4461@2|Bacteria,4NIBZ@976|Bacteroidetes,47QEU@768503|Cytophagia	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PliI
k59_199702_1	387093.SUN_0311	2.67e-34	129.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_199702_2	1165841.SULAR_09724	1.18e-76	231.0	COG1683@1|root,COG1683@2|Bacteria	2|Bacteria	K	Conserved Protein	ybgA	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_199702_3	1165841.SULAR_09729	1.11e-10	58.9	2ETDC@1|root,33KX5@2|Bacteria,1P8PA@1224|Proteobacteria,42UDD@68525|delta/epsilon subdivisions,2YPXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
k59_114346_1	69781.S8AMR1	7.17e-05	53.1	COG0318@1|root,COG1020@1|root,KOG1176@2759|Eukaryota,KOG1178@2759|Eukaryota,38HAR@33154|Opisthokonta,3NWBA@4751|Fungi,3QME2@4890|Ascomycota,20CXX@147545|Eurotiomycetes,3S540@5042|Eurotiales	4751|Fungi	IQ	nonribosomal peptide	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Condensation,NAD_binding_4,PP-binding
k59_6164_1	396588.Tgr7_2197	6e-63	209.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RR1J@1236|Gammaproteobacteria,1WVZY@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_13640_1	1121403.AUCV01000124_gene2974	8.9e-66	215.0	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2MMJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_168945_1	929558.SMGD1_0410	5.73e-125	382.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,dCache_2
k59_191846_1	247634.GPB2148_797	2.38e-89	270.0	COG0583@1|root,COG0583@2|Bacteria,1RGTE@1224|Proteobacteria,1S543@1236|Gammaproteobacteria,1JA5U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0583 Transcriptional regulator	-	-	-	ko:K21699	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_60207_1	2340.JV46_16140	1.97e-87	259.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1J5V2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_60207_2	1298865.H978DRAFT_3835	2.53e-46	152.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,46787@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_122359_1	765913.ThidrDRAFT_3163	1.61e-40	141.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1WXMB@135613|Chromatiales	135613|Chromatiales	M	Soluble lytic murein transglycosylase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
k59_122359_2	2340.JV46_11220	3.65e-54	180.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria,1J7AU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	DUF218 domain	Z012_07930	GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	DUF218
k59_184141_1	697282.Mettu_0065	2.38e-48	170.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	twitching motility protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_245839_1	693986.MOC_4070	0.000519	45.4	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2TS08@28211|Alphaproteobacteria,1JTA7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_176159_1	1205908.AKXW01000026_gene750	2.6e-05	48.5	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S8DT@1236|Gammaproteobacteria,1XX0Z@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
k59_176159_2	1122194.AUHU01000003_gene1955	1.6e-69	219.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,1S275@1236|Gammaproteobacteria,466SI@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_176159_3	1195246.AGRI_14885	1.16e-06	49.7	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,465IG@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_245840_1	1168034.FH5T_07050	1.64e-75	226.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_245840_2	553171.HMPREF0648_1024	1.87e-06	48.5	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,2FS1V@200643|Bacteroidia	976|Bacteroidetes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_145888_1	592015.HMPREF1705_01710	1.2e-14	68.9	COG1942@1|root,COG1942@2|Bacteria	2|Bacteria	S	isomerase activity	MA20_05500	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_145888_2	1128427.KB904821_gene1786	9.83e-51	172.0	COG4301@1|root,COG4301@2|Bacteria	2|Bacteria	S	dimethylhistidine N-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
k59_99028_1	247634.GPB2148_1516	2.33e-20	88.6	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1J4VY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0568 DNA-directed RNA polymerase, sigma subunit	rpoS	GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_99028_2	314285.KT71_02842	4.91e-54	171.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1SA21@1236|Gammaproteobacteria,1JAEZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
k59_199718_1	1313421.JHBV01000008_gene4397	9.88e-05	50.8	COG4886@1|root,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1IZK8@117747|Sphingobacteriia	976|Bacteroidetes	M	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
k59_214973_1	631362.Thi970DRAFT_04554	6.49e-67	213.0	COG3005@1|root,COG3005@2|Bacteria,1QZ6I@1224|Proteobacteria,1RXZD@1236|Gammaproteobacteria,1X0FD@135613|Chromatiales	135613|Chromatiales	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6176_1	313596.RB2501_05070	3.8e-121	362.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_60223_1	102129.Lepto7375DRAFT_0843	3.93e-22	98.6	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_176165_1	1165841.SULAR_03043	1.95e-52	175.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	PFAM SufBD protein	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
k59_176165_2	1165841.SULAR_03038	8.94e-91	271.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,42PD0@68525|delta/epsilon subdivisions,2YNP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_52422_2	243365.CV_0874	1.73e-25	100.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,2VSPM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_68147_1	762903.Pedsa_2549	2.41e-23	106.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_230280_1	33035.JPJF01000101_gene3279	1.52e-09	66.6	COG2972@1|root,COG2972@2|Bacteria,1TW41@1239|Firmicutes,24AHF@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
k59_6178_1	1121921.KB898713_gene1735	5.43e-16	85.5	COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Transglut_core
k59_145897_1	313596.RB2501_07660	9.36e-131	379.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,1HYAW@117743|Flavobacteriia	976|Bacteroidetes	G	Sugar kinases, ribokinase family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_60226_1	313596.RB2501_13779	3.03e-68	223.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HX7D@117743|Flavobacteriia	976|Bacteroidetes	V	Multidrug transporter MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_99045_1	1461693.ATO10_08257	4.82e-18	84.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2U404@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Auxin efflux carrier family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_99045_2	1123053.AUDG01000009_gene3739	2.85e-12	68.2	COG0457@1|root,COG0457@2|Bacteria,1MZ33@1224|Proteobacteria,1SARA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,TPR_12
k59_222808_2	357276.EL88_23565	1.95e-13	77.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,2FM0Q@200643|Bacteroidia,4ARFR@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
k59_168962_1	396588.Tgr7_0226	1.8e-197	565.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_168962_2	2340.JV46_18890	4.96e-16	77.4	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1J7ED@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG1459 Type II secretory pathway, component PulF	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_99050_1	395493.BegalDRAFT_0437	2.96e-57	198.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,GAF,GAF_2,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,Response_reg
k59_83294_1	220664.PFL_2493	9.37e-20	94.4	2ARNE@1|root,31GZ4@2|Bacteria,1QENI@1224|Proteobacteria,1SIDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75890_1	240015.ACP_3313	1.42e-41	144.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JMQ0@204432|Acidobacteriia	204432|Acidobacteriia	F	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_99061_1	761193.Runsl_5353	5.26e-38	143.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_153017_1	323261.Noc_3022	5.59e-96	298.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales	135613|Chromatiales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_230301_1	1165841.SULAR_06103	1.14e-110	320.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42RFS@68525|delta/epsilon subdivisions,2YP62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_230301_2	1165841.SULAR_06098	3.47e-27	108.0	COG0642@1|root,COG2205@2|Bacteria,1QZNK@1224|Proteobacteria,42R3C@68525|delta/epsilon subdivisions,2YP1R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_21492_1	1283300.ATXB01000001_gene1395	2.99e-84	255.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1XDVR@135618|Methylococcales	135618|Methylococcales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_60233_1	1123401.JHYQ01000024_gene1266	9.76e-86	264.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,461R6@72273|Thiotrichales	72273|Thiotrichales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_29387_1	360094.PXO_04844	4.69e-127	371.0	COG3335@1|root,COG3335@2|Bacteria,1MW8A@1224|Proteobacteria,1RY10@1236|Gammaproteobacteria,1X3VX@135614|Xanthomonadales	135614|Xanthomonadales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k59_222823_1	387093.SUN_0170	1.07e-81	257.0	COG1246@1|root,COG2172@1|root,COG1246@2|Bacteria,COG2172@2|Bacteria,1QZN7@1224|Proteobacteria,43CKZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_145917_1	1296416.JACB01000010_gene1601	7.32e-58	197.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2YKE2@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_191873_1	2340.JV46_09240	6.94e-109	328.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1J503@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k59_241778_1	2340.JV46_17130	6.73e-82	254.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1J4Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_226295_1	387093.SUN_1885	3.88e-103	303.0	COG1376@1|root,COG1376@2|Bacteria,1Q44E@1224|Proteobacteria,42Y80@68525|delta/epsilon subdivisions,2YR1Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_203142_2	439235.Dalk_1742	4.83e-50	181.0	COG0457@1|root,COG0846@1|root,COG1672@1|root,COG0457@2|Bacteria,COG0846@2|Bacteria,COG1672@2|Bacteria,1Q25D@1224|Proteobacteria,437SG@68525|delta/epsilon subdivisions,2WWCB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_148893_1	1165841.SULAR_05103	1.66e-117	348.0	COG0232@1|root,COG0232@2|Bacteria	2|Bacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141296_2	998674.ATTE01000001_gene712	4.11e-22	90.9	COG4113@1|root,COG4113@2|Bacteria,1N9W0@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_2136_2	1165841.SULAR_04587	3.35e-87	268.0	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2YMK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1
k59_241779_1	396588.Tgr7_0992	2.36e-155	461.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_63900_1	1165841.SULAR_05758	5.97e-122	355.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_9898_1	313596.RB2501_02015	1.46e-136	392.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_156663_1	1255043.TVNIR_2014	9.22e-44	156.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_63907_1	1165841.SULAR_00555	3.39e-65	199.0	2AK3E@1|root,31AT6@2|Bacteria,1Q635@1224|Proteobacteria,432B1@68525|delta/epsilon subdivisions,2YSJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63907_2	387093.SUN_0826	5.04e-33	121.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_133470_1	323261.Noc_0598	2.04e-60	198.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales	135613|Chromatiales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
k59_56117_1	215803.DB30_2166	2.32e-36	134.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_118178_1	1236959.BAMT01000002_gene2097	5.26e-30	108.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,2VU3I@28216|Betaproteobacteria,2KN4F@206350|Nitrosomonadales	206350|Nitrosomonadales	J	PFAM ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_79474_1	388413.ALPR1_21088	6.46e-87	294.0	COG1361@1|root,COG3210@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11
k59_2152_1	1165841.SULAR_05728	9.25e-75	226.0	COG0711@1|root,COG0711@2|Bacteria,1Q2G9@1224|Proteobacteria,42VN4@68525|delta/epsilon subdivisions,2YQBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the ATPase B chain family	atpF'	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_187703_1	29581.BW37_02833	4.7e-30	114.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2VSHT@28216|Betaproteobacteria,474EC@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
k59_148916_1	1165841.SULAR_03113	1.97e-26	102.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,42YWZ@68525|delta/epsilon subdivisions,2YRHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_148916_2	1121875.KB907549_gene1918	7.42e-15	74.7	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2158_1	98439.AJLL01000103_gene3617	4.05e-27	108.0	COG2199@1|root,COG3706@2|Bacteria,1G3NI@1117|Cyanobacteria,1JK6B@1189|Stigonemataceae	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_203167_1	981085.XP_010088417.1	2.94e-13	69.3	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta,4JS2T@91835|fabids	35493|Streptophyta	C	Ribulose bisphosphate carboxylase, large chain	rbcL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.1.3.15,4.1.1.39,6.4.1.2	ko:K01601,ko:K01963	ko00061,ko00620,ko00630,ko00640,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00630,map00640,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00165,M00166,M00376,M00532	R00024,R00742,R03140,R04386	RC00040,RC00172,RC00253,RC00367,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_133481_1	1168034.FH5T_17700	1.37e-80	255.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FN98@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_210885_1	3649.evm.model.supercontig_89.21	9.48e-38	130.0	2E3CF@1|root,2R1SP@2759|Eukaryota,383GK@33090|Viridiplantae,3GX0Z@35493|Streptophyta,3I1GY@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210885_2	3880.AES58602	1.45e-30	120.0	COG1005@1|root,COG3344@1|root,KOG4768@2759|Eukaryota,KOG4770@2759|Eukaryota,37KUX@33090|Viridiplantae,3GHBI@35493|Streptophyta,4JTJX@91835|fabids	35493|Streptophyta	A	NADH dehydrogenase (quinone) activity	matR	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2
k59_210885_3	72658.Bostr.12863s0004.1.p	6.53e-167	472.0	2CVK7@1|root,2RS7A@2759|Eukaryota,37RP9@33090|Viridiplantae,3GGMM@35493|Streptophyta	35493|Streptophyta	S	MttB protein	mttB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	-	-	-	-	-	-	-	-	-	TatC
k59_2159_1	1470591.BW41_00023	7.21e-51	175.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,2TR58@28211|Alphaproteobacteria,2K0CK@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_226317_1	870187.Thini_2168	3.63e-156	449.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Iron-sulfur cluster binding protein	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_203168_1	595460.RRSWK_02760	1.15e-17	89.4	COG2268@1|root,COG2268@2|Bacteria,2IXVC@203682|Planctomycetes	203682|Planctomycetes	S	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9910_1	1268240.ATFI01000004_gene4381	1.85e-61	206.0	COG2931@1|root,COG2931@2|Bacteria,4PPPT@976|Bacteroidetes,2G178@200643|Bacteroidia	976|Bacteroidetes	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_17428_1	1049564.TevJSym_aw00060	1.06e-73	233.0	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	dsrS	-	-	-	-	-	-	-	-	-	-	-	-
k59_17428_2	395493.BegalDRAFT_2669	3.75e-13	69.3	COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,1NEBU@1224|Proteobacteria,1RYA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_40829_1	1168034.FH5T_01730	3.37e-122	360.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_180050_1	1408473.JHXO01000012_gene382	2.03e-94	289.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,2FMIU@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
k59_133489_2	291112.PAU_00582	1.01e-37	137.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422	Thymidylat_synt
k59_172251_1	1168034.FH5T_12110	2.22e-49	165.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,2FNES@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_172251_2	1168034.FH5T_12120	7.28e-94	276.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,2FNRJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
k59_33308_1	1333998.M2A_0140	1.38e-78	253.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,4BP7M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_156677_1	1168034.FH5T_05795	4.6e-123	384.0	COG3250@1|root,COG3250@2|Bacteria,4NKZX@976|Bacteroidetes,2FNTC@200643|Bacteroidia	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
k59_187733_1	326297.Sama_2312	3.16e-08	57.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,2Q9ER@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_187733_2	1123279.ATUS01000003_gene440	2.27e-21	90.1	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1J4WA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_164581_1	1121101.HMPREF1532_01995	3.1e-43	163.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMCC@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_94961_1	1165841.SULAR_09504	5.73e-77	235.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2YR7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
k59_2184_1	1165841.SULAR_07300	4.65e-108	330.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_79487_1	1408473.JHXO01000011_gene3144	2.79e-117	356.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,2FNBD@200643|Bacteroidia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_195900_1	234267.Acid_2264	4.54e-87	274.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
k59_95292_3	29730.Gorai.001G160300.1	2.3e-37	135.0	2ESJY@1|root,2SV48@2759|Eukaryota,381J0@33090|Viridiplantae,3GQNG@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118542_1	1121405.dsmv_1764	1.13e-66	220.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MIQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_110673_1	999550.KI421507_gene1327	5.54e-47	167.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_203525_1	395493.BegalDRAFT_1286	1.16e-93	284.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149276_1	1123399.AQVE01000006_gene3553	8.81e-93	279.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,460EX@72273|Thiotrichales	72273|Thiotrichales	KO	TIGRFAM Hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_149276_2	670307.HYPDE_28363	9.56e-10	58.9	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3N7QG@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_95297_1	880073.Calab_1684	5.65e-25	99.4	2EC6I@1|root,33651@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
k59_95297_2	1168034.FH5T_03785	4.66e-12	67.8	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I
k59_211191_1	1056820.KB900663_gene3872	1.79e-11	60.5	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,2PP5G@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	PTS HPr component phosphorylation site	ptsO	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698	-	ko:K08485,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1	-	-	PTS-HPr
k59_211191_2	713587.THITH_14685	5.36e-27	104.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,1WYYD@135613|Chromatiales	135613|Chromatiales	G	system, fructose subfamily IIA component	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
k59_211191_3	765914.ThisiDRAFT_0195	1.86e-73	231.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales	135613|Chromatiales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_79780_2	1165841.SULAR_06308	1.85e-93	273.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42T1B@68525|delta/epsilon subdivisions,2YPHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_234635_1	1121405.dsmv_0420	4.6e-16	77.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria,2MIWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_234635_2	1121405.dsmv_0419	8.52e-99	292.0	COG1309@1|root,COG1309@2|Bacteria,1R4VA@1224|Proteobacteria,42PZX@68525|delta/epsilon subdivisions,2WK4I@28221|Deltaproteobacteria,2MI67@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_25583_2	4641.GSMUA_AchrUn_randomP21780_001	1.25e-153	481.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,3KRI7@4447|Liliopsida	35493|Streptophyta	K	Dna-directed rna polymerase	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_2523_1	751994.AGIG01000035_gene357	2.7e-123	369.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7VQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	soxB	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_149283_1	1165841.SULAR_06793	5.11e-113	336.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_157061_1	316067.Geob_0648	6.96e-06	56.2	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,43TUT@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
k59_137058_1	1121904.ARBP01000006_gene3775	1.24e-80	256.0	COG1797@1|root,COG1797@2|Bacteria,4NF1V@976|Bacteroidetes,47P08@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_105907_1	1165841.SULAR_08197	3.92e-133	392.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_222334_1	290398.Csal_2398	1.28e-64	218.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XIPX@135619|Oceanospirillales	135619|Oceanospirillales	S	mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_206669_1	926692.AZYG01000040_gene1492	6.12e-23	100.0	COG0535@1|root,COG0535@2|Bacteria,1UMP8@1239|Firmicutes,24BXU@186801|Clostridia,3WABZ@53433|Halanaerobiales	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,Fer4_14,PDZ,PDZ_2,Radical_SAM
k59_222335_1	484018.BACPLE_01947	2.35e-13	70.1	COG3086@1|root,COG3086@2|Bacteria,4NV0R@976|Bacteroidetes,2FS4Y@200643|Bacteroidia,4AQM8@815|Bacteroidaceae	976|Bacteroidetes	T	Positive regulator of sigma(E), RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k59_137073_1	1121374.KB891585_gene2264	3.93e-29	112.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
k59_137073_2	1120953.AUBH01000001_gene1150	3.4e-15	74.3	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710	adh_short_C2
k59_67701_1	3659.XP_004162281.1	1.83e-22	93.6	2CHYC@1|root,2S3QA@2759|Eukaryota,37V66@33090|Viridiplantae,3GJP6@35493|Streptophyta,4JUFF@91835|fabids	35493|Streptophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbE	-	-	ko:K02707,ko:K02713	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559,Cytochrom_B559a,PsbL
k59_5687_1	313596.RB2501_03175	2.71e-63	214.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_222342_1	391625.PPSIR1_02461	1.52e-20	94.0	2AB1F@1|root,310F3@2|Bacteria,1R7ZR@1224|Proteobacteria,43579@68525|delta/epsilon subdivisions,2WZI8@28221|Deltaproteobacteria,2Z27G@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
k59_152553_1	521719.ATXQ01000001_gene311	8.24e-21	89.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RMVZ@1236|Gammaproteobacteria,1YGIX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Cysteine-rich domain	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
k59_90607_1	1249627.D779_4009	3.18e-107	321.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,1RQ6N@1236|Gammaproteobacteria,1WWGR@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_222344_1	572477.Alvin_1769	1.18e-65	210.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_237786_2	1000565.METUNv1_01250	2.79e-65	214.0	2E11Z@1|root,32WHR@2|Bacteria,1N6I4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_206689_1	1165841.SULAR_03762	1.01e-106	321.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_145372_1	1385515.N791_03955	1.41e-59	195.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1X34P@135614|Xanthomonadales	135614|Xanthomonadales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_137089_2	1217714.F975_02341	2.97e-47	164.0	COG2865@1|root,COG2865@2|Bacteria,1MXG1@1224|Proteobacteria,1RY9W@1236|Gammaproteobacteria,3NJWR@468|Moraxellaceae	1236|Gammaproteobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
k59_44312_1	1118235.CAJH01000053_gene3144	1.39e-44	164.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1PTWJ@1224|Proteobacteria,1RZH5@1236|Gammaproteobacteria,1X55X@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,Peptidase_M1
k59_90611_1	1089552.KI911559_gene3107	1.14e-42	161.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2JQPJ@204441|Rhodospirillales	204441|Rhodospirillales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k59_82825_1	1165841.SULAR_09964	6.81e-106	306.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,42QP7@68525|delta/epsilon subdivisions,2YNWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
k59_168374_1	1168034.FH5T_22015	4.44e-71	219.0	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,2FMT1@200643|Bacteroidia	976|Bacteroidetes	KT	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_13252_1	395493.BegalDRAFT_0070	0.000222	49.3	COG1361@1|root,COG2706@1|root,COG4409@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria,COG4409@2|Bacteria,1NB7P@1224|Proteobacteria,1SCSF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
k59_52001_2	1121374.KB891586_gene2650	1.12e-71	223.0	2BYAF@1|root,2ZWH8@2|Bacteria,1RBZ8@1224|Proteobacteria,1S3VD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3581)	SO4011	-	-	-	-	-	-	-	-	-	-	-	DUF3581
k59_168376_1	871963.Desdi_1961	3.55e-39	143.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,261D3@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_105941_1	992406.RIA_0629	1.65e-15	81.6	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWKW@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_82828_1	32057.KB217478_gene5843	2.66e-55	189.0	COG1524@1|root,COG3379@1|root,COG1524@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Phosphodiest,TPR_19
k59_168380_1	1101195.Meth11DRAFT_1881	2.47e-16	72.8	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,2KMYK@206350|Nitrosomonadales	206350|Nitrosomonadales	C	TIGRFAM ferredoxin, 2Fe-2S type, ISC system	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
k59_145383_1	1500893.JQNB01000001_gene2627	1.05e-94	313.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_75390_1	880070.Cycma_0161	2.54e-42	157.0	2DBFZ@1|root,2Z91A@2|Bacteria,4PKZZ@976|Bacteroidetes,47YBY@768503|Cytophagia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_5707_1	562743.JH976442_gene678	5.97e-36	133.0	COG2227@1|root,COG2227@2|Bacteria,1UXZZ@1239|Firmicutes,4HG9W@91061|Bacilli	91061|Bacilli	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_13264_1	1173020.Cha6605_2100	3.42e-28	113.0	COG3344@1|root,COG3344@2|Bacteria,1G791@1117|Cyanobacteria	1117|Cyanobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_160327_1	713587.THITH_12095	2.93e-14	70.9	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_160327_2	243233.MCA2627	8.74e-23	99.8	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XDUM@135618|Methylococcales	135618|Methylococcales	S	Competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_191385_1	388413.ALPR1_01110	2.25e-88	287.0	COG4188@1|root,COG4188@2|Bacteria,4NKC2@976|Bacteroidetes,47TN2@768503|Cytophagia	976|Bacteroidetes	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
k59_44315_1	1123400.KB904747_gene615	9.16e-83	258.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,45ZQG@72273|Thiotrichales	72273|Thiotrichales	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k59_98519_1	1335757.SPICUR_09410	4.51e-41	147.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1WWM6@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_230096_1	1118054.CAGW01000072_gene1701	6.82e-10	58.5	2CK5I@1|root,2ZEE3@2|Bacteria,1W4ZH@1239|Firmicutes,4HZTI@91061|Bacilli,2713S@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_199562_1	375286.mma_1283	1.01e-74	239.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,472BS@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_129842_1	243233.MCA2447	1.7e-42	159.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XDRZ@135618|Methylococcales	135618|Methylococcales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_199565_1	1165841.SULAR_09854	1.36e-59	186.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2YPE3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_199565_2	1165841.SULAR_09859	4.14e-27	108.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2YMUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_222618_1	1121937.AUHJ01000009_gene1553	1.36e-119	358.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,1RNS0@1236|Gammaproteobacteria,46ADA@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome D1 heme domain	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_129844_1	1165841.SULAR_01430	5.46e-121	347.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2YNHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_214808_1	1165841.SULAR_05748	5.88e-92	276.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_214808_2	1165841.SULAR_05753	7.93e-34	122.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_52284_1	226186.BT_1217	2.32e-19	85.5	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,2FMT1@200643|Bacteroidia,4AKZZ@815|Bacteroidaceae	976|Bacteroidetes	K	COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_145676_1	1165841.SULAR_09119	1.18e-119	360.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_21314_1	1123517.JOMR01000001_gene145	5.46e-58	196.0	2C8CV@1|root,2Z8NV@2|Bacteria,1MWPM@1224|Proteobacteria,1RQRC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3095)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3095
k59_214814_2	1168034.FH5T_13105	6.58e-34	131.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,2FPXW@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase, S9A B C family, catalytic domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k59_137355_1	2340.JV46_10370	5.85e-109	327.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1J5MK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0498 Threonine synthase	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
k59_222622_1	15368.BRADI3G27278.1	4.38e-162	461.0	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta,3KWKY@4447|Liliopsida,3IN22@38820|Poales	35493|Streptophyta	G	Ribulose bisphosphate carboxylase large chain, N-terminal domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_152814_1	1380355.JNIJ01000006_gene3041	5.66e-36	132.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,3JR1M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_207042_1	1173028.ANKO01000042_gene848	2.91e-20	90.9	COG1192@1|root,COG1192@2|Bacteria,1G2RD@1117|Cyanobacteria,1H9YS@1150|Oscillatoriales	1117|Cyanobacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,HSDR_N_2
k59_207042_2	211165.AJLN01000100_gene4326	1.76e-20	93.6	COG1475@1|root,COG1475@2|Bacteria,1G6Y3@1117|Cyanobacteria,1JKJX@1189|Stigonemataceae	1117|Cyanobacteria	K	DNA binding	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_145677_1	1026882.MAMP_00105	5.3e-86	270.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	ychM	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	iSbBS512_1146.SbBS512_E1370	STAS,Sulfate_transp
k59_199574_1	313596.RB2501_07515	8.77e-78	249.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_37106_1	395493.BegalDRAFT_0440	1.46e-42	142.0	COG3255@1|root,COG3255@2|Bacteria,1RI49@1224|Proteobacteria,1S38T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83116_1	629265.PMA4326_00035	9.2e-13	74.3	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,1Z9AQ@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Pfam:HipA_N	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k59_5976_1	1123020.AUIE01000001_gene2282	2.61e-74	239.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1YDKY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Bacterial regulatory protein, Fis family	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_137356_1	2340.JV46_23660	1.17e-61	211.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1J4BX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_122230_1	1165841.SULAR_00095	5.2e-136	401.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_122230_2	1165841.SULAR_00100	3.63e-07	51.2	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_230110_1	1415778.JQMM01000001_gene1500	4.47e-77	244.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1J4J4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_24406_1	761193.Runsl_3512	2.82e-09	58.2	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47N8Q@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k59_163718_1	153948.NAL212_2326	4.04e-58	190.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,3727J@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Aminotransferase, class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_101850_2	384765.SIAM614_17164	1.7e-100	305.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_24411_1	349521.HCH_05411	2.35e-48	167.0	COG3853@1|root,COG3853@2|Bacteria,1MY18@1224|Proteobacteria,1RZ1H@1236|Gammaproteobacteria,1XMQ5@135619|Oceanospirillales	135619|Oceanospirillales	P	Toxic anion resistance	-	-	-	-	-	-	-	-	-	-	-	-	TelA
k59_70803_1	1385935.N836_32435	3.9e-10	60.5	COG0697@1|root,COG0697@2|Bacteria,1G4U5@1117|Cyanobacteria,1HFB2@1150|Oscillatoriales	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_109573_1	7668.SPU_003319-tr	4.31e-80	270.0	2CMP4@1|root,2QR56@2759|Eukaryota,39VQX@33154|Opisthokonta,3BR69@33208|Metazoa,3E64E@33213|Bilateria	33208|Metazoa	S	Pao retrotransposon peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_125055_1	1123228.AUIH01000121_gene3492	7.25e-23	93.2	COG3436@1|root,COG3436@2|Bacteria,1RGZ6@1224|Proteobacteria,1S3VM@1236|Gammaproteobacteria,1XSA0@135619|Oceanospirillales	135619|Oceanospirillales	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
k59_179258_2	655815.ZPR_3419	7.49e-48	156.0	COG3436@1|root,COG3436@2|Bacteria,4NV0F@976|Bacteroidetes,1I3XN@117743|Flavobacteriia	976|Bacteroidetes	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_186925_2	1237149.C900_00535	1.7e-09	55.8	2CIH2@1|root,2ZTG0@2|Bacteria,4NNM2@976|Bacteroidetes,47VGE@768503|Cytophagia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
k59_171550_3	339670.Bamb_1333	1.77e-24	107.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VP1R@28216|Betaproteobacteria,1K48K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_171550_4	1589733.A0A0C5AIV3_9CAUD	7.66e-42	142.0	4QBKQ@10239|Viruses,4QQM7@28883|Caudovirales,4QIAS@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage translational regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109576_1	1453498.LG45_01370	8.07e-24	101.0	COG3677@1|root,COG3677@2|Bacteria,4NJC5@976|Bacteroidetes,1I0Y5@117743|Flavobacteriia,2NVCC@237|Flavobacterium	976|Bacteroidetes	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_217974_1	1165841.SULAR_05323	3.44e-99	300.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1306_1	69319.XP_008553664.1	5.28e-58	199.0	2CQJ9@1|root,2R501@2759|Eukaryota,39VPP@33154|Opisthokonta,3BH26@33208|Metazoa,3D1HX@33213|Bilateria,41ZNG@6656|Arthropoda,3SQT2@50557|Insecta,46K5B@7399|Hymenoptera	33208|Metazoa	S	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9165_1	706587.Desti_1638	3.15e-26	108.0	COG1028@1|root,COG1545@1|root,COG3255@1|root,COG3425@1|root,COG1028@2|Bacteria,COG1545@2|Bacteria,COG3255@2|Bacteria,COG3425@2|Bacteria,1MXNQ@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_27450	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_9165_2	439235.Dalk_3190	1.65e-38	138.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42NW7@68525|delta/epsilon subdivisions,2WKQD@28221|Deltaproteobacteria,2MJ4I@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_16667_1	1165841.SULAR_09759	1.06e-80	243.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2YNQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_140602_1	314230.DSM3645_11212	1e-66	228.0	COG1352@1|root,COG2201@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,2IWSR@203682|Planctomycetes	203682|Planctomycetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,PAS_9,Response_reg
k59_24426_1	156889.Mmc1_1816	2.06e-140	409.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,2U11A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k59_194670_1	2340.JV46_27250	1.11e-222	641.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1J4N3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164	PBP1_TM,Transgly,Transpeptidase,UB2H
k59_40070_1	765913.ThidrDRAFT_2772	2.03e-65	211.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_40070_2	472759.Nhal_1091	4.03e-77	232.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1WYAE@135613|Chromatiales	135613|Chromatiales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_40070_3	1207076.ALAT01000221_gene3511	1.37e-10	63.5	COG3071@1|root,COG3071@2|Bacteria,1N8NX@1224|Proteobacteria,1SACE@1236|Gammaproteobacteria,1Z0AG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
k59_86410_1	56110.Oscil6304_2591	4.14e-56	196.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria	1117|Cyanobacteria	T	Transmembrane sensor domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc,PAS_4,PAS_9
k59_94225_1	984262.SGRA_2994	2.09e-36	139.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Kelch_1,Malectin,PKD,Peptidase_M6,Peptidase_S8
k59_16674_1	395493.BegalDRAFT_2485	2.34e-48	175.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_63164_1	1168034.FH5T_13830	1.09e-128	389.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
k59_140611_1	477184.KYC_08040	2.61e-35	134.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
k59_101861_2	1123228.AUIH01000007_gene2557	1.92e-24	100.0	COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,1QYI0@1224|Proteobacteria,1S3HY@1236|Gammaproteobacteria,1XP9C@135619|Oceanospirillales	135619|Oceanospirillales	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
k59_140617_1	398720.MED217_06267	6.72e-54	177.0	COG1305@1|root,COG1305@2|Bacteria,4NF4N@976|Bacteroidetes,1I0MX@117743|Flavobacteriia,2XK0A@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_40079_1	7070.TC001495-PA	3.3e-31	126.0	2CMGD@1|root,2QQ9V@2759|Eukaryota,39B3J@33154|Opisthokonta,3BKG5@33208|Metazoa,3CTR5@33213|Bilateria,41V8V@6656|Arthropoda,3SQAF@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2
k59_155969_1	1168034.FH5T_05025	1.49e-33	129.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_32488_2	1168034.FH5T_01705	7.95e-76	236.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia	2|Bacteria	F	Psort location CytoplasmicMembrane, score 10.00	tqsA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_240999_1	1121035.AUCH01000003_gene1401	9.82e-19	85.1	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,2KWAW@206389|Rhodocyclales	206389|Rhodocyclales	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
k59_86419_1	754035.Mesau_00922	2.96e-61	194.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
k59_171569_1	929713.NIASO_20190	1.1e-55	189.0	COG1073@1|root,COG1073@2|Bacteria,4NI6C@976|Bacteroidetes,1INXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyl xylan esterase	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
k59_117400_1	236097.ADG881_278	8.35e-50	166.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria,1XNB9@135619|Oceanospirillales	135619|Oceanospirillales	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
k59_210060_1	1265313.HRUBRA_01558	9.18e-85	261.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria,1J8NX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_55486_1	2340.JV46_27860	7.17e-159	459.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1JBHG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	ArsB,CitMHS
k59_9177_1	1340493.JNIF01000003_gene1600	1.63e-45	158.0	COG4974@1|root,COG4974@2|Bacteria,3Y3D0@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_9177_2	195250.CM001776_gene960	4.12e-45	159.0	COG4974@1|root,COG4974@2|Bacteria,1G4JW@1117|Cyanobacteria,1GZF3@1129|Synechococcus	1117|Cyanobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_179289_1	261292.Nit79A3_0361	6.63e-95	284.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2WGYA@28216|Betaproteobacteria,374QX@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_202457_1	377629.TERTU_1823	2.17e-21	88.2	2EB38@1|root,33540@2|Bacteria,1NBMZ@1224|Proteobacteria,1SFQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_202457_2	1397528.Q671_10585	7.74e-32	122.0	COG3436@1|root,COG3436@2|Bacteria,1MYAC@1224|Proteobacteria,1T2KH@1236|Gammaproteobacteria,1XIK6@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_86430_1	1469613.JT55_12390	7.07e-17	82.8	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2U6G5@28211|Alphaproteobacteria,3FDWV@34008|Rhodovulum	28211|Alphaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA
k59_109604_1	298654.FraEuI1c_7056	7.03e-20	83.6	COG4104@1|root,COG4104@2|Bacteria,2GV8K@201174|Actinobacteria	201174|Actinobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
k59_109604_2	1056820.KB900633_gene2032	8.73e-13	66.6	COG4381@1|root,COG4381@2|Bacteria,1N08Q@1224|Proteobacteria,1SSCY@1236|Gammaproteobacteria,2PQ4E@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Mu-like prophage protein gp46	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_117405_1	1121481.AUAS01000011_gene4980	1.93e-30	115.0	COG3484@1|root,COG3484@2|Bacteria,4NGR7@976|Bacteroidetes,47MX7@768503|Cytophagia	976|Bacteroidetes	O	Proteasome subunit	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
k59_117405_2	357808.RoseRS_3273	3.62e-29	114.0	COG1305@1|root,COG1305@2|Bacteria,2GABB@200795|Chloroflexi,374X3@32061|Chloroflexia	32061|Chloroflexia	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_210065_1	1265313.HRUBRA_01489	4.07e-86	262.0	2DG8R@1|root,2ZUYV@2|Bacteria,1R8VA@1224|Proteobacteria,1T0PJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
k59_9178_1	1128912.GMES_2654	2.47e-09	55.8	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,466WM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_9178_2	1198232.CYCME_0386	6.7e-62	207.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,4607G@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_40089_1	313596.RB2501_03210	9.62e-122	361.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia	976|Bacteroidetes	F	nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_210068_1	565045.NOR51B_448	1.01e-08	57.4	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,1J9AQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	proteins of the AP superfamily	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_187319_1	1123355.JHYO01000031_gene1608	6.59e-73	231.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,371HI@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Reductase C-terminal	thcD	-	1.14.13.111,1.18.1.3	ko:K00529,ko:K16968	ko00071,ko00360,ko00920,ko01120,ko01220,map00071,map00360,map00920,map01120,map01220	M00545	R02000,R06782,R06783,R09513	RC00098,RC02556	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
k59_71213_1	375286.mma_3363	1.71e-35	135.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,4725Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
k59_181823_1	1168034.FH5T_09770	3.49e-81	249.0	COG2010@1|root,COG2010@2|Bacteria,4NV2A@976|Bacteroidetes,2FY82@200643|Bacteroidia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_181823_2	1168034.FH5T_09775	1.2e-103	312.0	COG5557@1|root,COG5557@2|Bacteria,4NF8T@976|Bacteroidetes,2FW4G@200643|Bacteroidia	976|Bacteroidetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_243562_1	1165841.SULAR_01445	1.31e-189	535.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DEAD DEAH box helicase	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_197360_1	1168034.FH5T_11540	2.73e-78	247.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia	976|Bacteroidetes	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_18961_1	313603.FB2170_07055	1.11e-27	116.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia,2PGID@252356|Maribacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_88851_1	84531.JMTZ01000043_gene1236	1.86e-36	138.0	COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,1X3Z6@135614|Xanthomonadales	135614|Xanthomonadales	E	Splits dipeptides with a prolyl residue in the C- terminal position	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_73309_1	648757.Rvan_0586	3.95e-16	77.4	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U1PX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_73309_2	2340.JV46_11950	6.18e-21	85.1	2ESGD@1|root,335Y7@2|Bacteria,1NC37@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_235936_1	1250278.JQNQ01000001_gene3159	1.32e-42	144.0	2CDPK@1|root,32RR8@2|Bacteria,4NSHW@976|Bacteroidetes,1I402@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_235936_2	313596.RB2501_05345	3.54e-26	97.1	COG1476@1|root,COG1476@2|Bacteria,4NV53@976|Bacteroidetes,1I527@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_112197_1	1121035.AUCH01000004_gene351	4.21e-60	191.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2VTUE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_73315_1	1165841.SULAR_06038	3.55e-113	341.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_150625_1	1237149.C900_03945	5.53e-52	177.0	COG4538@1|root,COG4538@2|Bacteria,4PKKQ@976|Bacteroidetes	976|Bacteroidetes	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SnoaL_2
k59_173909_1	1234664.AMRO01000027_gene1269	2.08e-80	253.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1WEH4@129337|Geobacillus	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_220545_1	237368.SCABRO_01651	1.45e-58	187.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_127707_1	387093.SUN_0476	5.7e-60	189.0	COG4951@1|root,COG4951@2|Bacteria,1PC94@1224|Proteobacteria,42NUB@68525|delta/epsilon subdivisions,2YMWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Domain of unknown function (DUF1882)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1882
k59_57836_1	1168034.FH5T_11895	1.11e-132	388.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,2FMC3@200643|Bacteroidia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_135257_1	765912.Thimo_1660	8.56e-42	156.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1WWVT@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M1, membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_81272_1	1168034.FH5T_05690	2.02e-21	94.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,2FMIV@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k59_81272_2	1168034.FH5T_05685	4.3e-35	129.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,2FPVJ@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	porV	-	-	-	-	-	-	-	-	-	-	-	-
k59_104235_2	138119.DSY2769	1.39e-12	69.7	COG2184@1|root,COG2184@2|Bacteria,1TNY6@1239|Firmicutes,249XE@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k59_119945_1	349741.Amuc_1290	9.69e-77	256.0	COG0823@1|root,COG1262@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,46TMC@74201|Verrucomicrobia,2IVG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135275_1	450851.PHZ_c3434	1.52e-23	101.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,2KFRC@204458|Caulobacterales	204458|Caulobacterales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k59_243571_1	1298867.AUES01000059_gene4745	1.24e-66	218.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2TU9Q@28211|Alphaproteobacteria,3JW1M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_11561_1	391625.PPSIR1_00710	3.11e-34	132.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42MPE@68525|delta/epsilon subdivisions,2X630@28221|Deltaproteobacteria,2Z38I@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_158478_1	2340.JV46_14590	9.44e-123	376.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1J4ES@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_158478_2	2340.JV46_14600	1.66e-140	406.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1J587@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
k59_158478_3	1331060.RLDS_09630	0.000442	42.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U3RF@28211|Alphaproteobacteria,2K4KP@204457|Sphingomonadales	204457|Sphingomonadales	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_173921_1	864702.OsccyDRAFT_2545	4.99e-49	178.0	COG0004@1|root,COG0642@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HHZA@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_104239_1	105559.Nwat_1158	1.67e-67	226.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1WWBJ@135613|Chromatiales	135613|Chromatiales	M	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_204893_1	870187.Thini_1156	8.04e-64	213.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,460G5@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
k59_104240_1	1165841.SULAR_02933	6.67e-49	162.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	hydC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_104240_2	1165841.SULAR_02938	9.73e-191	543.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hydB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_228044_1	2340.JV46_27320	3.24e-136	404.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1J4FF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_112226_1	1070319.CAGGBEG34_180129	1.22e-41	156.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_104244_1	387093.SUN_1164	2.26e-86	282.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_104244_2	1165841.SULAR_00815	2.25e-78	238.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2YP9T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
k59_204902_1	1392498.JQLH01000001_gene3241	1.38e-34	129.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia,2PGGP@252356|Maribacter	976|Bacteroidetes	P	Citrate transporter	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_204902_2	1121875.KB907546_gene2181	9.55e-48	158.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1HXWI@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_127746_1	925984.E5AGA3_9CAUD	3.2e-05	48.5	4QFP5@10239|Viruses,4QWU1@35237|dsDNA viruses  no RNA stage,4QSRX@28883|Caudovirales,4QJQA@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212683_1	1142394.PSMK_15730	2.69e-10	68.2	COG0653@1|root,COG0653@2|Bacteria,2IXIT@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_143223_1	396588.Tgr7_0574	5.37e-24	99.4	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_143223_2	765914.ThisiDRAFT_2289	6.38e-37	137.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales	135613|Chromatiales	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,RLAN,RimK
k59_50093_1	385682.AFSL01000026_gene627	2.73e-06	48.9	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,3XINU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_43152_1	4081.Solyc06g060030.1.1	1.92e-120	373.0	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae,3GG2K@35493|Streptophyta,44UC5@71274|asterids	35493|Streptophyta	L	Mitochondrial protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve,zf-CCHC
k59_236643_1	3711.Bra018468.1-P	2.27e-11	70.5	COG4886@1|root,2QVPY@2759|Eukaryota,37JUP@33090|Viridiplantae,3G728@35493|Streptophyta,3HPSV@3699|Brassicales	35493|Streptophyta	T	Belongs to the protein kinase superfamily. Ser Thr protein kinase family	-	GO:0000003,GO:0001653,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0008152,GO:0009791,GO:0009845,GO:0009888,GO:0009960,GO:0009987,GO:0010154,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0022414,GO:0023052,GO:0032501,GO:0032502,GO:0036211,GO:0038023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045087,GO:0046777,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0061458,GO:0065007,GO:0071704,GO:0071944,GO:0090351,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_8,Pkinase
k59_221152_1	1121920.AUAU01000006_gene355	1.22e-13	68.9	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
k59_112776_1	395493.BegalDRAFT_0576	5.5e-68	217.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,45ZNQ@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_19670_1	2340.JV46_27740	1e-132	388.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,1JB8I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_221155_1	998088.B565_1393	9.23e-58	190.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1Y5GI@135624|Aeromonadales	135624|Aeromonadales	P	oligopeptide ABC transporter, ATP-binding protein	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_198055_1	2340.JV46_28520	4.18e-26	104.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1J4CZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	urtC	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_198055_2	1116375.VEJY3_06845	5.27e-54	183.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XUB9@135623|Vibrionales	135623|Vibrionales	E	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_58487_1	2340.JV46_03640	1.49e-74	236.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1J8NJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	mltB	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031402,GO:0031420,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044462,GO:0044464,GO:0046872,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	iECABU_c1320.ECABU_c29710,iNRG857_1313.NRG857_13215	SLT_2
k59_190153_1	985255.APHJ01000039_gene235	1.23e-28	103.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia,2P6YV@244698|Gillisia	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_190153_2	1233950.IW22_15295	9.01e-23	92.0	COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,1II63@117743|Flavobacteriia,3ZS22@59732|Chryseobacterium	976|Bacteroidetes	S	RNA-binding protein	ykfA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_190153_3	1223410.KN050846_gene570	1.33e-06	48.5	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,1I1ZM@117743|Flavobacteriia	976|Bacteroidetes	K	Cold-shock protein	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
k59_97314_2	395493.BegalDRAFT_3076	8.21e-51	161.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	fdxN	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
k59_97314_4	316056.RPC_4315	7.45e-22	89.4	COG1393@1|root,COG1393@2|Bacteria,1MZ7Z@1224|Proteobacteria,2UCXA@28211|Alphaproteobacteria,3JZ0Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_228690_1	1249627.D779_1733	4.24e-10	60.8	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_228690_2	314278.NB231_15228	1.1e-64	197.0	COG0347@1|root,COG0347@2|Bacteria,1RIY4@1224|Proteobacteria,1S67U@1236|Gammaproteobacteria,1WYIZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
k59_58500_2	1280680.AUJU01000010_gene490	3.83e-12	67.4	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,4BWIS@830|Butyrivibrio	186801|Clostridia	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_174557_1	985762.SAGN_01325	4.88e-18	88.2	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,4GY5R@90964|Staphylococcaceae	91061|Bacilli	KLT	Serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_74059_1	391623.TERMP_02214	3.96e-05	52.0	COG0286@1|root,COG1002@1|root,COG2810@1|root,arCOG02632@2157|Archaea,arCOG02635@2157|Archaea,arCOG05724@2157|Archaea,2Y89W@28890|Euryarchaeota,244PR@183968|Thermococci	183968|Thermococci	V	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
k59_66327_1	864051.BurJ1DRAFT_0701	1.44e-26	100.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,1KKVP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Lactoylglutathione lyase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_66327_2	933262.AXAM01000046_gene140	7.64e-40	148.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2MI0S@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
k59_151292_1	1298593.TOL_1324	6.82e-16	85.9	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,1XMP6@135619|Oceanospirillales	135619|Oceanospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_120644_1	1502852.FG94_01649	2.58e-21	90.1	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,4739T@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_120644_2	1121127.JAFA01000090_gene3621	8.06e-41	150.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VNU5@28216|Betaproteobacteria,1K1AA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_12159_1	83219.PM02_00440	4.8e-23	94.7	COG3177@1|root,COG3177@2|Bacteria,1RJSD@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
k59_236668_1	385682.AFSL01000014_gene2731	0.00098	42.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,2FNAU@200643|Bacteroidia,3XIKC@558415|Marinilabiliaceae	976|Bacteroidetes	M	Transglycosylase	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_236668_2	886379.AEWI01000026_gene424	1.83e-21	93.2	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,2FMSF@200643|Bacteroidia,3XINJ@558415|Marinilabiliaceae	976|Bacteroidetes	L	Bacterial DNA topoisomeraes I ATP-binding domain	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_205621_1	1057002.KB905370_gene3155	2.5e-13	75.1	COG2202@1|root,COG3447@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3447@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,4B9N5@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_3,PAS_8,PAS_9
k59_182515_1	1121405.dsmv_2306	2.32e-144	427.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MN0D@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Peptidase family M41	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_221174_1	187272.Mlg_0452	1.35e-139	431.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_185414_1	261292.Nit79A3_1366	3.46e-24	103.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
k59_177395_1	592031.GCWU000322_00071	3.36e-10	61.6	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,25VE1@186806|Eubacteriaceae	186801|Clostridia	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_22778_1	351348.Maqu_2062	3.39e-18	86.7	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,469RS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	transport system, fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_22778_2	1317118.ATO8_03621	8.09e-15	71.2	COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,2UABJ@28211|Alphaproteobacteria,4KMWC@93682|Roseivivax	28211|Alphaproteobacteria	T	Universal stress protein	MA20_08295	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_84603_1	756272.Plabr_2666	1.66e-95	300.0	COG0480@1|root,COG0480@2|Bacteria,2IXUD@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_185419_1	56110.Oscil6304_4466	2.45e-73	235.0	COG5433@1|root,COG5433@2|Bacteria,1G2IT@1117|Cyanobacteria,1HHU1@1150|Oscillatoriales	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_46060_1	1123401.JHYQ01000023_gene1225	1.19e-84	260.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1T9Q0@1236|Gammaproteobacteria,461SP@72273|Thiotrichales	72273|Thiotrichales	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_61544_1	631362.Thi970DRAFT_04114	2.43e-31	122.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,1RQ8X@1236|Gammaproteobacteria,1WW6F@135613|Chromatiales	135613|Chromatiales	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_61544_2	765913.ThidrDRAFT_2898	1.17e-40	145.0	2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,1RZVK@1236|Gammaproteobacteria,1WWI9@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_185427_2	1165841.SULAR_04457	1.33e-67	211.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_193137_1	91464.S7335_298	1.2e-50	176.0	COG0376@1|root,COG0376@2|Bacteria,1G1NM@1117|Cyanobacteria,1GZK3@1129|Synechococcus	1117|Cyanobacteria	H	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_38619_1	646529.Desaci_0288	8.86e-25	108.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,dCache_1
k59_162099_1	999541.bgla_1g18060	6.01e-38	145.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,1K532@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_107816_1	1165841.SULAR_04202	5.34e-94	278.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,42VAD@68525|delta/epsilon subdivisions,2YPP1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,TehB
k59_154309_1	857087.Metme_1801	1.96e-40	142.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1XEKP@135618|Methylococcales	135618|Methylococcales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_154309_2	637389.Acaty_c0783	3.47e-70	225.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,2NBT2@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_201035_1	935863.AWZR01000002_gene1088	5.64e-21	98.6	COG0457@1|root,COG0515@1|root,COG3063@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3063@2|Bacteria,1MVEU@1224|Proteobacteria,1S0IU@1236|Gammaproteobacteria,1X52Q@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
k59_38627_1	358681.BBR47_37630	2.87e-12	68.6	COG4675@1|root,COG4675@2|Bacteria,1V6CH@1239|Firmicutes,4HK20@91061|Bacilli,26YUI@186822|Paenibacillaceae	91061|Bacilli	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k59_123725_1	1454004.AW11_02365	8.63e-156	461.0	COG3385@1|root,COG3385@2|Bacteria,1RA6A@1224|Proteobacteria,2VUMQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_201040_2	1232437.KL662042_gene2011	2.46e-36	130.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,42Y9C@68525|delta/epsilon subdivisions,2WUJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_177434_1	1165841.SULAR_04537	2.2e-98	291.0	COG0845@1|root,COG0845@2|Bacteria,1QE6S@1224|Proteobacteria,42QGG@68525|delta/epsilon subdivisions,2YNSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cmeE	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_247135_1	694427.Palpr_1002	1.75e-34	121.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,2FU46@200643|Bacteroidia,22YSM@171551|Porphyromonadaceae	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_123796_1	1165841.SULAR_05538	1.22e-78	238.0	COG0745@1|root,COG0745@2|Bacteria,1Q5DC@1224|Proteobacteria,42R42@68525|delta/epsilon subdivisions,2YNXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_123796_2	1165841.SULAR_05533	1.7e-20	89.7	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_30966_1	643867.Ftrac_1069	1.69e-30	125.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes,47UGU@768503|Cytophagia	976|Bacteroidetes	V	Protein export membrane protein	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_139287_1	1165841.SULAR_07173	7.26e-28	108.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2YN3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
k59_139287_2	1121943.KB899995_gene847	2.46e-20	88.2	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,1S99N@1236|Gammaproteobacteria,1XKMP@135619|Oceanospirillales	135619|Oceanospirillales	O	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,PPC
k59_139328_1	118168.MC7420_784	7.64e-72	228.0	COG3772@1|root,COG3772@2|Bacteria,1GCAA@1117|Cyanobacteria	1117|Cyanobacteria	S	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131554_1	187272.Mlg_0559	2.46e-36	137.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales	135613|Chromatiales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_170228_1	1298867.AUES01000090_gene2982	1.2e-24	108.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U1YP@28211|Alphaproteobacteria,3JRUE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,VWA,VWA_2
k59_108354_1	395493.BegalDRAFT_3427	2.01e-51	172.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_46428_1	713586.KB900536_gene2882	3.05e-95	286.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WX6I@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_38709_1	545264.KB898760_gene2500	9.62e-93	301.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_38711_1	1250232.JQNJ01000001_gene1333	2.54e-28	110.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1HY3S@117743|Flavobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_38711_2	313596.RB2501_06460	4.4e-24	95.1	2E32X@1|root,32Y35@2|Bacteria,4NUUU@976|Bacteroidetes,1I54Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123809_1	880073.Calab_3356	1.82e-70	239.0	COG0737@1|root,COG1506@1|root,COG2356@1|root,COG4935@1|root,COG0737@2|Bacteria,COG1506@2|Bacteria,COG2356@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.17.18	ko:K05996,ko:K06889,ko:K07214	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CotH,Peptidase_S9,SBP_bac_8,SLH
k59_216669_1	977880.RALTA_B1019	1.21e-97	314.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2VHSN@28216|Betaproteobacteria,1K184@119060|Burkholderiaceae	28216|Betaproteobacteria	O	type VI secretion ATPase, ClpV1 family	clpV	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_139358_1	2340.JV46_11990	2.54e-157	460.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1J4TI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_116080_1	49964.Q94MS4_9CAUD	1.08e-44	163.0	4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses  no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_185731_1	1123261.AXDW01000011_gene490	3.02e-28	107.0	2EA0N@1|root,33462@2|Bacteria,1N9KZ@1224|Proteobacteria,1SR45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_224416_1	29730.Gorai.012G029800.1	0.000983	48.1	2CM8R@1|root,2QPMW@2759|Eukaryota,38A3V@33090|Viridiplantae,3GXG7@35493|Streptophyta	35493|Streptophyta	S	Indole-3-acetic acid-amido synthetase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009526,GO:0009536,GO:0009941,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	ko:K14487	ko04075,map04075	-	-	-	ko00000,ko00001	-	-	-	GH3
k59_38719_1	935548.KI912159_gene1725	1.64e-107	341.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,43ITA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	Efflux pump membrane transporter	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_131565_1	1249975.JQLP01000001_gene3242	1.75e-30	114.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1HX48@117743|Flavobacteriia,2P64M@244698|Gillisia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_131565_2	1286632.P278_28370	9.68e-23	96.3	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,4PKJ5@976|Bacteroidetes,1HY50@117743|Flavobacteriia	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_54200_1	1165841.SULAR_01533	0.000248	42.7	COG2274@1|root,COG2274@2|Bacteria,1MXTI@1224|Proteobacteria	1224|Proteobacteria	V	ABC transporter, (ATP-binding protein)	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_54200_2	1165841.SULAR_07550	2.7e-105	317.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_61962_1	313596.RB2501_09180	1.86e-94	286.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_61974_1	1165841.SULAR_01688	1.89e-72	226.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_61974_2	1165841.SULAR_01693	4.79e-28	105.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2YPJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_7759_1	1121875.KB907549_gene1813	1.2e-71	219.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia	976|Bacteroidetes	FJ	Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
k59_7759_2	313596.RB2501_12849	2.37e-28	113.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_80576_1	754476.Q7A_2833	9.23e-20	89.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_80576_2	572477.Alvin_2862	2.79e-46	161.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_219872_1	1123399.AQVE01000003_gene2017	6.58e-50	168.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,4603B@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_88230_1	2340.JV46_04850	6.64e-63	198.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,1RYDR@1236|Gammaproteobacteria,1J915@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_88230_2	2340.JV46_04860	9.65e-44	153.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,1SYJD@1236|Gammaproteobacteria,1J88Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_134646_1	869213.JCM21142_214	9.21e-33	124.0	COG3025@1|root,COG3025@2|Bacteria,4NM6K@976|Bacteroidetes,47PAH@768503|Cytophagia	976|Bacteroidetes	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
k59_103641_1	1123400.KB904817_gene1462	1.81e-59	184.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,460QJ@72273|Thiotrichales	72273|Thiotrichales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_103641_2	349521.HCH_06231	8.33e-64	205.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XH22@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_204324_1	481448.Minf_0846	2.75e-31	123.0	COG0224@1|root,COG0224@2|Bacteria,46Y59@74201|Verrucomicrobia,37GHH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	ATP synthase	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_212015_1	1458275.AZ34_14495	3.81e-29	115.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VP1R@28216|Betaproteobacteria,4ADBA@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_34380_1	1189612.A33Q_2982	7.31e-67	229.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47U4M@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_57251_1	75379.Tint_1656	8.98e-21	91.3	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	cbbR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_212022_1	1247649.D560_0787	1.1e-53	188.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VPT3@28216|Betaproteobacteria,3T8RH@506|Alcaligenaceae	28216|Betaproteobacteria	V	ABC transporter transmembrane region	sunT	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_65052_1	1313265.JNIE01000003_gene1368	2.38e-89	273.0	COG3329@1|root,COG3329@2|Bacteria,2G4J8@200783|Aquificae	200783|Aquificae	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
k59_88248_1	717231.Flexsi_0631	4.12e-41	145.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_142549_1	1382359.JIAL01000001_gene1313	8.71e-82	254.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	neuC	GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_181286_1	1131269.AQVV01000010_gene2440	2.54e-05	52.4	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_103649_3	4081.Solyc00g021640.2.1	4.74e-77	240.0	28P22@1|root,2QVNI@2759|Eukaryota,37SGH@33090|Viridiplantae,3GFX8@35493|Streptophyta	35493|Streptophyta	S	ribosomal protein S4	-	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
k59_18443_1	1165841.SULAR_04622	5.08e-133	382.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_196796_3	330214.NIDE1391	3.97e-55	181.0	COG0047@1|root,COG0047@2|Bacteria,3J10Q@40117|Nitrospirae	40117|Nitrospirae	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k59_181287_1	1288826.MSNKSG1_00556	1.32e-191	541.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_220358_1	1165841.SULAR_07470	9.66e-137	396.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_158309_1	742727.HMPREF9447_02142	6.43e-25	109.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,2FNIQ@200643|Bacteroidia,4AKE2@815|Bacteroidaceae	976|Bacteroidetes	L	COG COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_135123_1	1415778.JQMM01000001_gene2181	3.77e-88	275.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_189276_2	2340.JV46_09630	2.12e-37	137.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_204754_1	1121405.dsmv_0753	2.47e-22	95.1	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42PEN@68525|delta/epsilon subdivisions,2WJ9F@28221|Deltaproteobacteria,2MIQU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_204754_2	1167006.UWK_03243	3.5e-114	337.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WJYH@28221|Deltaproteobacteria,2MI0A@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_104097_2	234267.Acid_4494	1.56e-46	158.0	COG1595@1|root,COG1595@2|Bacteria,3Y7YB@57723|Acidobacteria	2|Bacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
k59_135128_1	1165841.SULAR_00590	9.95e-100	302.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_112075_2	314285.KT71_02627	2.17e-21	94.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34772_1	118797.XP_007457195.1	2.74e-29	111.0	COG0094@1|root,COG0198@1|root,KOG0398@2759|Eukaryota,KOG1708@2759|Eukaryota,38D2V@33154|Opisthokonta	33154|Opisthokonta	J	ribosomal large subunit assembly	mrpl7	GO:0000027,GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031974,GO:0032543,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_34772_2	519989.ECTPHS_13123	3.96e-44	145.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1WYNJ@135613|Chromatiales	135613|Chromatiales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_34772_3	296591.Bpro_0489	1.27e-10	58.5	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,4ADJT@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_135132_1	1121403.AUCV01000013_gene3916	1.64e-63	211.0	COG2367@1|root,COG2367@2|Bacteria,1R7HB@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
k59_112077_1	485915.Dret_1070	4.83e-88	281.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2MAN7@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_81106_1	195250.CM001776_gene545	4.17e-10	64.3	COG0475@1|root,COG0475@2|Bacteria,1G03Z@1117|Cyanobacteria,1GYNY@1129|Synechococcus	1117|Cyanobacteria	P	COG0475 Kef-type K transport systems, membrane components	nhaS3	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_189294_2	1165841.SULAR_07320	2.06e-88	263.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2YNYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_127566_1	1165841.SULAR_09669	2.84e-50	168.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_127566_2	1165841.SULAR_09674	1.21e-115	340.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2YMJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_57682_1	1123276.KB893260_gene2564	6.93e-05	45.8	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_96488_1	998674.ATTE01000001_gene2740	1.59e-129	382.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales	72273|Thiotrichales	L	Exonuclease C-terminal	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k59_73183_1	985867.AEWF01000008_gene1043	2.36e-16	82.4	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_143039_1	1217710.F969_03677	7.96e-26	105.0	COG3039@1|root,COG3039@2|Bacteria,1MXP1@1224|Proteobacteria,1RSBM@1236|Gammaproteobacteria,3NIY5@468|Moraxellaceae	1236|Gammaproteobacteria	L	There are 9 addittional ORFs identical to this one	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
k59_49954_1	1500894.JQNN01000001_gene4167	3.91e-23	94.7	COG0546@1|root,COG0546@2|Bacteria,1R903@1224|Proteobacteria,2VJVS@28216|Betaproteobacteria,47645@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_49954_3	640081.Dsui_1844	6.76e-07	50.4	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria,2VJ5F@28216|Betaproteobacteria,2KVDV@206389|Rhodocyclales	206389|Rhodocyclales	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_143041_1	1121090.KB894710_gene1455	6.22e-20	93.2	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZM3Z@1386|Bacillus	91061|Bacilli	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_76827_1	247490.KSU1_D0349	2.49e-42	156.0	COG0457@1|root,COG0457@2|Bacteria,2IWTH@203682|Planctomycetes	203682|Planctomycetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_19
k59_14596_1	1121459.AQXE01000002_gene1288	2.57e-23	99.4	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_14596_2	472759.Nhal_2114	3.61e-67	207.0	29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,1S6VD@1236|Gammaproteobacteria,1X0VV@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192818_1	582515.KR51_00009880	2.34e-15	80.1	COG0438@1|root,COG1216@1|root,COG4122@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG4122@2|Bacteria,1G7V8@1117|Cyanobacteria	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_14600_1	697282.Mettu_2763	4.55e-61	197.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1XF15@135618|Methylococcales	135618|Methylococcales	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	-	-	-	-	-	-	-	-	-	-	CheR,CheR_N
k59_68996_1	523791.Kkor_2282	4.2e-111	328.0	COG0482@1|root,COG0482@2|Bacteria,1QV6H@1224|Proteobacteria,1RQSV@1236|Gammaproteobacteria,1XNSX@135619|Oceanospirillales	135619|Oceanospirillales	J	tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_Me_trans
k59_192820_1	1168034.FH5T_06525	3.73e-36	136.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_192820_2	694427.Palpr_1915	6.89e-10	63.2	COG0042@1|root,COG0042@2|Bacteria,4NFRH@976|Bacteroidetes,2FMTW@200643|Bacteroidia,22X5R@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_38252_1	765912.Thimo_1749	1.06e-24	105.0	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76829_1	1165841.SULAR_00360	4.66e-100	305.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_107433_2	1123401.JHYQ01000023_gene1192	1.04e-20	91.7	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,461DX@72273|Thiotrichales	72273|Thiotrichales	I	aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_130976_1	1307436.PBF_16224	2.36e-05	52.4	COG4585@1|root,COG5001@1|root,COG4585@2|Bacteria,COG5001@2|Bacteria,1UI7N@1239|Firmicutes,4ISN0@91061|Bacilli,1ZS9J@1386|Bacillus	91061|Bacilli	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MHYT,PAS,PAS_4,PAS_9
k59_100085_1	365046.Rta_03940	1.34e-50	174.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,1RA75@1224|Proteobacteria,2VQQD@28216|Betaproteobacteria,4ADRH@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_100085_2	1173024.KI912149_gene6090	7.81e-20	87.4	COG0562@1|root,COG0562@2|Bacteria,1GBR1@1117|Cyanobacteria,1JJYM@1189|Stigonemataceae	1117|Cyanobacteria	M	UDP-galactopyranose mutase	-	-	-	-	-	-	-	-	-	-	-	-	GLF,NAD_binding_8
k59_239639_1	1168034.FH5T_17425	9.75e-49	166.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_239639_2	1168034.FH5T_17430	2.95e-66	202.0	COG1993@1|root,COG1993@2|Bacteria,4NX2K@976|Bacteroidetes,2FZ1Q@200643|Bacteroidia	976|Bacteroidetes	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
k59_239639_3	1168034.FH5T_17435	6.4e-36	124.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,2FUP5@200643|Bacteroidia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_208607_1	1198232.CYCME_0494	5.12e-09	57.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,460EZ@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k59_208607_2	1218084.BBJK01000066_gene4884	2.2e-34	122.0	COG3791@1|root,COG3791@2|Bacteria,1N263@1224|Proteobacteria,2VVWM@28216|Betaproteobacteria,1K7X3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating GFA	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_53830_1	1449063.JMLS01000003_gene1947	4.2e-23	97.1	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,4HBXC@91061|Bacilli,26T0J@186822|Paenibacillaceae	91061|Bacilli	C	ferredoxin	porC	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_6,Fer4_7,POR
k59_53830_2	1121121.KB894293_gene1307	5.93e-28	113.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,4HCVY@91061|Bacilli,26R4C@186822|Paenibacillaceae	91061|Bacilli	C	Pyruvate synthase	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
k59_201097_1	313603.FB2170_07744	6.15e-13	67.0	28QB8@1|root,2ZCTU@2|Bacteria,4NP7R@976|Bacteroidetes,1I1M5@117743|Flavobacteriia,2PHF7@252356|Maribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
k59_201097_2	313596.RB2501_08350	9.78e-73	223.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1HWMQ@117743|Flavobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_185490_1	1165841.SULAR_06168	4.04e-83	248.0	COG2406@1|root,COG2406@2|Bacteria,1RE25@1224|Proteobacteria,42PJ1@68525|delta/epsilon subdivisions,2YMUJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ferritin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_185490_2	387093.SUN_1879	1.21e-37	135.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_46154_1	768671.ThimaDRAFT_2628	6.79e-110	323.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1WW8S@135613|Chromatiales	135613|Chromatiales	S	PFAM conserved	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k59_53831_1	313598.MED152_02130	1.16e-91	277.0	2A263@1|root,30QGN@2|Bacteria,4NMYV@976|Bacteroidetes,1I29B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53832_1	998674.ATTE01000001_gene1999	1.92e-76	244.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,4604V@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_216247_1	948106.AWZT01000030_gene4802	1.86e-52	175.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,2VJZI@28216|Betaproteobacteria,1K0UP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_131408_1	589865.DaAHT2_1993	3.77e-23	97.8	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2WK7V@28221|Deltaproteobacteria,2MIDN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
k59_131408_2	443144.GM21_1947	3.54e-78	248.0	COG0280@1|root,COG0280@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
k59_201104_1	857087.Metme_4055	1.64e-25	99.4	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,1XH0F@135618|Methylococcales	135618|Methylococcales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_201104_3	1274524.BSONL12_10986	2.69e-07	50.1	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,4HPCF@91061|Bacilli,1ZIW6@1386|Bacillus	91061|Bacilli	S	homolog of the cytoplasmic domain of flagellar protein FhlB	ylqH	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k59_53834_1	1255043.TVNIR_2693	5.65e-18	82.4	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	heptosyltransferase	rfaF	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	iECH74115_1262.ECH74115_4993,iECSP_1301.ECSP_4617,iECs_1301.ECs4498,iG2583_1286.G2583_4359,iZ_1308.Z5047	Glyco_transf_9
k59_162185_1	586413.CCDL010000002_gene1900	2.29e-19	94.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,23JT9@182709|Oceanobacillus	91061|Bacilli	L	Bacterial DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_247201_1	29730.Gorai.001G164600.1	1.53e-33	126.0	COG1007@1|root,KOG4668@2759|Eukaryota,37KKM@33090|Viridiplantae,3GCSG@35493|Streptophyta	35493|Streptophyta	C	ATP synthesis coupled electron transport	nad2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_247201_2	29730.Gorai.001G164600.1	7.53e-11	65.9	COG1007@1|root,KOG4668@2759|Eukaryota,37KKM@33090|Viridiplantae,3GCSG@35493|Streptophyta	35493|Streptophyta	C	ATP synthesis coupled electron transport	nad2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_154392_1	1123508.JH636449_gene7320	5.01e-11	65.5	COG0515@1|root,COG0515@2|Bacteria,2IX09@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_154392_2	713586.KB900536_gene2578	1.06e-30	117.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
k59_14991_1	1042375.AFPL01000054_gene2133	1.16e-18	85.5	COG0591@1|root,COG0642@1|root,COG4191@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,464E5@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0591 Na proline symporter	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg,SSF
k59_14991_3	497321.C664_09903	1.39e-07	52.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,2KVZ5@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_22918_1	395493.BegalDRAFT_2238	4.47e-105	322.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,45ZSA@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_193218_2	1238450.VIBNISOn1_160017	1.26e-12	65.9	COG1247@1|root,COG1247@2|Bacteria,1QUGY@1224|Proteobacteria,1T1YJ@1236|Gammaproteobacteria,1XVDF@135623|Vibrionales	135623|Vibrionales	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yhhY	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_46159_2	309801.trd_0700	3.13e-08	63.5	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia	189775|Thermomicrobia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_69457_1	713586.KB900536_gene463	1.54e-58	183.0	COG3791@1|root,COG3791@2|Bacteria,1PY7G@1224|Proteobacteria,1SXYP@1236|Gammaproteobacteria,1X1WI@135613|Chromatiales	135613|Chromatiales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_115736_1	1168034.FH5T_05150	8.6e-76	237.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia	976|Bacteroidetes	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_30828_1	1122604.JONR01000006_gene2533	3.55e-48	163.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1X4DA@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_84690_1	1121875.KB907547_gene3261	4.06e-77	257.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1HXWA@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_224172_1	1328313.DS2_15314	1.74e-29	119.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4655Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_231562_1	983544.Lacal_2806	5.18e-54	179.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_84693_1	265072.Mfla_1708	9.21e-45	155.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,2KKKM@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_239654_1	313596.RB2501_00906	1.33e-83	275.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_69463_1	1452718.JBOY01000021_gene719	1.94e-49	182.0	COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Psort location Cytoplasmic, score	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	Prim-Pol,Toprim_3,Toprim_4
k59_22929_1	765913.ThidrDRAFT_3454	2.78e-129	378.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1WVWD@135613|Chromatiales	135613|Chromatiales	C	PFAM malic	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_61678_2	1382359.JIAL01000001_gene1744	1.42e-55	194.0	COG1524@1|root,COG1524@2|Bacteria,3Y3RC@57723|Acidobacteria,2JHTZ@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
k59_138910_2	1165841.SULAR_00435	4.37e-30	109.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42SQX@68525|delta/epsilon subdivisions,2YPH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_231565_1	909663.KI867150_gene365	5.86e-79	242.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_15005_1	388467.A19Y_2223	7.56e-61	212.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	mcyA	-	-	ko:K16130	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,McyA_C,Methyltransf_12,PP-binding,PilZ
k59_115755_1	1121405.dsmv_3755	7.59e-43	144.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2MJW2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_239660_1	414684.RC1_2263	2.09e-13	72.8	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2JR48@204441|Rhodospirillales	204441|Rhodospirillales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_239660_2	313606.M23134_07937	1.34e-08	57.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_53853_1	639282.DEFDS_0510	2.02e-30	123.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GF0N@200930|Deferribacteres	200930|Deferribacteres	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_46175_2	745411.B3C1_17662	2.07e-48	164.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1J68Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_15006_1	398512.JQKC01000023_gene3346	5.01e-94	286.0	COG0012@1|root,COG0012@2|Bacteria,1UIBA@1239|Firmicutes,24DM9@186801|Clostridia	186801|Clostridia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131427_1	1158762.KB898046_gene547	1.7e-89	270.0	COG1116@1|root,COG1116@2|Bacteria,1R8N0@1224|Proteobacteria,1RYBX@1236|Gammaproteobacteria,1WY77@135613|Chromatiales	135613|Chromatiales	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_193239_1	1519464.HY22_06225	1.51e-19	87.0	2DBYH@1|root,2ZBV5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154410_1	1296416.JACB01000013_gene4391	3.8e-108	339.0	COG1680@1|root,COG1680@2|Bacteria,4NG6Z@976|Bacteroidetes,1HZ72@117743|Flavobacteriia,2YJIU@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,CBM9_1
k59_30850_1	156889.Mmc1_2438	5.63e-70	231.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2TRF9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Na phosphate symporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k59_165585_2	1268237.G114_08532	4.82e-12	66.2	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1Y4KI@135624|Aeromonadales	135624|Aeromonadales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
k59_142229_1	1121875.KB907548_gene1546	1.27e-106	328.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_41678_1	631362.Thi970DRAFT_03988	9e-19	90.1	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1WWK5@135613|Chromatiales	135613|Chromatiales	O	FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_157647_1	1165841.SULAR_02458	6.79e-07	50.4	COG2133@1|root,COG2133@2|Bacteria,1R0BJ@1224|Proteobacteria	1224|Proteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_157647_3	1165841.SULAR_02448	7.4e-43	142.0	2CBEP@1|root,32RT7@2|Bacteria,1MZXD@1224|Proteobacteria,42VUE@68525|delta/epsilon subdivisions,2YQCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_219630_1	504472.Slin_0653	3.84e-72	235.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,47MY3@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k59_3108_2	1165841.SULAR_02803	1.42e-108	315.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_188635_1	2340.JV46_02700	8.51e-61	199.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1J7KN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3	ko:K00113,ko:K11473	ko00564,ko00630,ko01100,ko01110,ko01120,ko01130,map00564,map00630,map01100,map01110,map01120,map01130	-	R00475,R00848	RC00029,RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
k59_26541_2	1166016.W5S_3103	5.33e-44	156.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1MR0Z@122277|Pectobacterium	1236|Gammaproteobacteria	H	DNA photolyase	phrB	GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0018298,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_65239_1	313596.RB2501_03420	5.53e-124	360.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_127279_1	1280001.BAOA01000077_gene3069	1.29e-45	169.0	COG1361@1|root,COG2304@1|root,COG2931@1|root,COG2982@1|root,COG3121@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3121@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XSBS@135623|Vibrionales	135623|Vibrionales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind,VWA_2
k59_26550_1	1165841.SULAR_02348	7.53e-83	251.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2YMKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	fecE	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k59_26550_2	1165841.SULAR_02343	1.51e-36	130.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2YMMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Abc transporter	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_227643_1	762968.HMPREF9441_00866	3.45e-122	365.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,2FNGK@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_103839_1	1165841.SULAR_06038	4.25e-18	83.2	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_103839_2	1165841.SULAR_06043	2.52e-112	340.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_3535_1	207954.MED92_10954	9.64e-100	305.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XHB9@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_80811_1	1123401.JHYQ01000008_gene419	2.94e-103	305.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,4609Y@72273|Thiotrichales	72273|Thiotrichales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_111832_1	998674.ATTE01000001_gene2233	5.26e-55	192.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,461TY@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase HrpB	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_3544_1	520709.F985_02564	8.4e-72	227.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RS16@1236|Gammaproteobacteria,3NSN8@468|Moraxellaceae	1236|Gammaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	lys	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
k59_34528_1	215803.DB30_3844	2.43e-68	231.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,438QJ@68525|delta/epsilon subdivisions,2X3XW@28221|Deltaproteobacteria,2YXIE@29|Myxococcales	28221|Deltaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
k59_18583_1	395493.BegalDRAFT_2200	7.95e-57	194.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,45ZWJ@72273|Thiotrichales	72273|Thiotrichales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_88453_1	983545.Glaag_1423	2.36e-28	109.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,464IP@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
k59_88453_2	631362.Thi970DRAFT_04134	4.34e-82	253.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1WXZ1@135613|Chromatiales	135613|Chromatiales	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
k59_72905_2	313596.RB2501_10462	2.33e-37	130.0	2DSID@1|root,32UT8@2|Bacteria,4NTWM@976|Bacteroidetes,1I4NX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_96253_1	1165841.SULAR_08040	3.52e-120	352.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_142784_2	1150474.JQJI01000004_gene418	7.54e-14	67.4	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
k59_111860_1	1190606.AJYG01000016_gene3371	1.13e-06	56.2	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XVA6@135623|Vibrionales	135623|Vibrionales	I	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
k59_88459_1	1123401.JHYQ01000019_gene1454	1.42e-48	176.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,46124@72273|Thiotrichales	72273|Thiotrichales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_111863_1	2340.JV46_04520	2.56e-39	140.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1JA45@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_3562_1	1226994.AMZB01000110_gene2007	1.93e-23	103.0	COG3712@1|root,COG3712@2|Bacteria,1RA2H@1224|Proteobacteria,1S794@1236|Gammaproteobacteria,1YKTZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	PT	Domain of unknown function (DUF4974)	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
k59_49755_1	1168034.FH5T_04225	1.15e-47	154.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,2FTZJ@200643|Bacteroidia	976|Bacteroidetes	J	ribosomal subunit interface protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_49755_2	1408473.JHXO01000006_gene1407	3.78e-40	140.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,2FNFK@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_142794_1	706587.Desti_3118	4.46e-27	115.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MQA8@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_235613_1	1415780.JPOG01000001_gene3152	3.09e-79	248.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,1RNDU@1236|Gammaproteobacteria,1XABV@135614|Xanthomonadales	135614|Xanthomonadales	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_57472_1	345341.KUTG_05610	3.88e-52	183.0	COG0476@1|root,COG0476@2|Bacteria,2GNQE@201174|Actinobacteria,4E98S@85010|Pseudonocardiales	201174|Actinobacteria	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_150300_1	583345.Mmol_0425	2.9e-33	134.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,2VMKQ@28216|Betaproteobacteria,2KKYJ@206350|Nitrosomonadales	206350|Nitrosomonadales	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_204556_1	998674.ATTE01000001_gene2168	2.35e-49	176.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,45ZN8@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_80858_1	1168034.FH5T_07815	3.22e-13	68.6	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,2FMA5@200643|Bacteroidia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_80858_2	1168034.FH5T_07810	1.23e-79	239.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,2FPJ4@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_18605_1	1166018.FAES_3079	5.46e-12	70.9	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47KW1@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
k59_34545_1	768671.ThimaDRAFT_3242	5.27e-57	192.0	COG0438@1|root,COG0438@2|Bacteria,1P8MT@1224|Proteobacteria,1S8IY@1236|Gammaproteobacteria,1X1IR@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_42104_1	1165841.SULAR_01873	1.64e-41	140.0	COG1853@1|root,COG1853@2|Bacteria,1RAIQ@1224|Proteobacteria,42QXX@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Flavin reductase like domain	flr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_42104_2	1165841.SULAR_09239	7.6e-41	141.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42UAY@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE1	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
k59_212343_1	1168034.FH5T_05690	1.89e-106	340.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,2FMIV@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k59_134915_1	233412.HD_1716	7.73e-75	234.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1Y6ZF@135625|Pasteurellales	135625|Pasteurellales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_34548_1	371042.NG99_07580	2.27e-47	167.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,3X5QI@551|Erwinia	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_49764_1	205918.Psyr_3556	2.47e-59	206.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1Z6D0@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_103882_1	395493.BegalDRAFT_0269	6.34e-53	180.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,1T4BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,Response_reg
k59_127336_2	1133850.SHJG_5895	9.25e-21	94.4	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
k59_127336_3	2340.JV46_26050	2.62e-106	313.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1J9IK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_26592_2	1217810.I7EWB7_9CAUD	1.78e-27	108.0	4QEFP@10239|Viruses,4QZ30@35237|dsDNA viruses  no RNA stage,4QS4Z@28883|Caudovirales,4QP1I@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119618_1	1122194.AUHU01000002_gene2481	2.64e-14	67.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,468RS@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	cspD	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_134927_1	1121011.AUCB01000056_gene4039	2.06e-78	249.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,23HR7@178469|Arenibacter	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_150307_1	237368.SCABRO_01744	1.06e-11	70.1	COG3666@1|root,COG3666@2|Bacteria,2J1Y1@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_88478_1	522306.CAP2UW1_3090	1.64e-31	117.0	COG0514@1|root,COG0514@2|Bacteria,1P06D@1224|Proteobacteria	1224|Proteobacteria	L	HRDC domain	-	-	-	-	-	-	-	-	-	-	-	-	HRDC
k59_220175_1	118173.KB235914_gene2616	2.66e-45	166.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_134930_1	261292.Nit79A3_1885	2.94e-17	85.9	COG0240@1|root,COG0240@2|Bacteria,1RED0@1224|Proteobacteria,2W2AD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_235618_1	1249627.D779_0911	2.95e-80	247.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales	135613|Chromatiales	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_235618_2	2340.JV46_16980	3.41e-21	86.3	COG3118@1|root,COG3118@2|Bacteria,1RI6E@1224|Proteobacteria,1S8B4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	Thioredoxin
k59_42122_1	443144.GM21_0720	2.71e-09	58.9	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,43THJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
k59_150311_1	318161.Sden_3303	1.8e-71	233.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,2QA9J@267890|Shewanellaceae	1236|Gammaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_142824_1	1165841.SULAR_05413	1.64e-53	174.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2YM8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_142824_2	1165841.SULAR_01528	4.69e-14	71.6	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_142825_1	879212.DespoDRAFT_01215	3.4e-109	325.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_96298_2	768671.ThimaDRAFT_3337	3.46e-44	163.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1WZIA@135613|Chromatiales	135613|Chromatiales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_204581_2	340177.Cag_0707	1.05e-18	79.3	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_246477_1	96561.Dole_0550	2.85e-77	247.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_69054_2	1165841.SULAR_02808	3.76e-62	207.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_7197_1	1172188.KB911826_gene243	0.000404	48.1	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_138499_1	1121937.AUHJ01000005_gene2191	4.52e-42	156.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,4657X@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k59_69055_1	1038869.AXAN01000006_gene823	4.46e-14	70.9	COG1637@1|root,COG1637@2|Bacteria,1N0QI@1224|Proteobacteria,2W483@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146926_1	118168.MC7420_1241	3.58e-34	135.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1H9WN@1150|Oscillatoriales	1117|Cyanobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
k59_200733_1	1123037.AUDE01000001_gene1673	2.94e-13	72.4	2E3AK@1|root,32SYY@2|Bacteria,4NSTE@976|Bacteroidetes,1IIAV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200733_2	1178825.ALIH01000007_gene1751	1.59e-15	75.1	2E3AK@1|root,32YA3@2|Bacteria,4PQ2A@976|Bacteroidetes,1IKYT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239308_1	1117647.M5M_12070	4.76e-15	80.5	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,1JA89@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k59_223847_1	387093.SUN_1164	1.72e-113	357.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_154023_2	1298593.TOL_3644	3.82e-52	173.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_246856_1	743722.Sph21_3064	7.5e-13	67.8	COG0500@1|root,COG0500@2|Bacteria,4NGY5@976|Bacteroidetes,1J0S7@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_246856_2	313596.RB2501_10192	6.07e-21	90.9	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215929_1	1408473.JHXO01000014_gene4075	1.76e-136	404.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_7205_1	1168034.FH5T_10400	2.02e-67	228.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes,2FM1V@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_30459_1	1035308.AQYY01000001_gene3294	1.37e-16	79.3	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_7207_1	2340.JV46_07230	4.32e-64	198.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1J6AP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_177122_1	1249997.JHZW01000002_gene896	6.33e-11	65.1	28HKZ@1|root,2Z7VP@2|Bacteria,4NFGM@976|Bacteroidetes,1HWRW@117743|Flavobacteriia,2PIAG@252356|Maribacter	976|Bacteroidetes	S	Protein of unknown function (DUF3050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3050
k59_92050_2	1168034.FH5T_16725	5.28e-30	110.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,2FSR0@200643|Bacteroidia	976|Bacteroidetes	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_231177_1	1165841.SULAR_06888	7.75e-87	266.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_84328_1	33876.JNXY01000039_gene6587	3.05e-09	58.9	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DBM6@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_84328_2	314260.PB2503_05882	3.8e-11	63.9	COG0697@1|root,COG0697@2|Bacteria,1PDMU@1224|Proteobacteria,2U0T9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_200752_1	985255.APHJ01000021_gene1562	1.84e-53	186.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia,2P5MI@244698|Gillisia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_200752_2	1168034.FH5T_18115	1.33e-81	243.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_100174_1	400682.PAC_15705790	5.93e-89	285.0	COG0843@1|root,COG1622@1|root,KOG4767@2759|Eukaryota,KOG4769@2759|Eukaryota,38JQ7@33154|Opisthokonta,3BGCX@33208|Metazoa	33208|Metazoa	C	electron transport coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	COX1,COX2
k59_53482_1	1408164.MOLA814_01179	2.81e-22	95.9	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VNRV@28216|Betaproteobacteria	28216|Betaproteobacteria	I	esterase	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,COesterase
k59_192907_1	1173027.Mic7113_3293	1.05e-57	202.0	COG0642@1|root,COG0784@1|root,COG3437@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG3437@2|Bacteria,1GPYK@1117|Cyanobacteria,1HHZI@1150|Oscillatoriales	1117|Cyanobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_2,PAS_3,PAS_4,PAS_9,PHY,Response_reg,dCache_1
k59_200757_1	1165841.SULAR_04157	2.48e-165	470.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_200757_2	1165841.SULAR_04152	1.96e-117	345.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_69072_1	1049564.TevJSym_ad00660	1.19e-111	324.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,1J5Q7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
k59_69072_2	1366050.N234_09705	1.84e-88	267.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,2VI8R@28216|Betaproteobacteria,1K1PX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cob(II)yrinic acid a,c-diamide reductase	bluB	-	1.13.11.79,2.1.1.107	ko:K02303,ko:K04719	ko00740,ko00860,ko01100,ko01110,ko01120,map00740,map00860,map01100,map01110,map01120	M00121	R03194,R09083	RC00003,RC00435,RC00871,RC02413	ko00000,ko00001,ko00002,ko01000	-	-	-	Nitroreductase
k59_22507_2	29760.VIT_00s0246g00230.t01	6.06e-45	159.0	2C63X@1|root,2S2ZC@2759|Eukaryota,37VFD@33090|Viridiplantae,3GJPI@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_208246_1	1168034.FH5T_02925	1.61e-82	260.0	COG1034@1|root,COG4624@1|root,COG1034@2|Bacteria,COG4624@2|Bacteria,4P26W@976|Bacteroidetes,2FXEU@200643|Bacteroidia	976|Bacteroidetes	C	Iron hydrogenase small subunit	-	-	1.12.1.3	ko:K18332	-	-	-	-	ko00000,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4_9,NADH-G_4Fe-4S_3
k59_84349_1	1408445.JHXP01000016_gene3560	5.24e-85	267.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria,1JCZW@118969|Legionellales	118969|Legionellales	I	Acyl-CoA dehydrogenase, middle domain	aidB	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
k59_246869_1	1385517.N800_11130	4.35e-104	330.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales	135614|Xanthomonadales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_76911_1	522772.Dacet_1102	7.37e-23	97.8	COG0811@1|root,COG0811@2|Bacteria,2GFCQ@200930|Deferribacteres	200930|Deferribacteres	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_107531_2	1265313.HRUBRA_00537	5.03e-56	183.0	28NHW@1|root,2ZBJG@2|Bacteria,1RBJB@1224|Proteobacteria,1S31B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215947_2	742159.HMPREF0004_4712	3.25e-17	78.2	COG3108@1|root,COG3108@2|Bacteria	2|Bacteria	S	Peptidase M15	Z012_12330	-	-	ko:K02395,ko:K03791,ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	GH19	-	Peptidase_M15_3,Peptidase_M15_4
k59_185173_1	6500.XP_005099231.1	1.31e-59	208.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BHR3@33208|Metazoa,3CUIP@33213|Bilateria	33208|Metazoa	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_115466_1	313596.RB2501_06765	1.18e-21	97.8	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,SPOR
k59_146957_1	395493.BegalDRAFT_1310	9.49e-143	412.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,4607F@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_215951_1	156889.Mmc1_3249	3.34e-67	229.0	COG0841@1|root,COG3087@1|root,COG0841@2|Bacteria,COG3087@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_231225_1	391587.KAOT1_17033	9.25e-18	83.2	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_231225_2	1286632.P278_26710	7.61e-73	223.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_215955_1	1165841.SULAR_09129	2.64e-107	319.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_100196_1	1395571.TMS3_0112320	8.02e-42	143.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_100196_2	1247726.MIM_c24020	2.5e-15	74.7	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,3T3J6@506|Alcaligenaceae	28216|Betaproteobacteria	S	HAD-hyrolase-like	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_14690_1	754436.JCM19237_1239	0.000133	47.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,1S6VB@1236|Gammaproteobacteria,1XT6N@135623|Vibrionales	135623|Vibrionales	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_208279_2	1165841.SULAR_09609	6.22e-34	122.0	COG1387@1|root,COG1387@2|Bacteria,1MX8T@1224|Proteobacteria,43BI2@68525|delta/epsilon subdivisions,2YT8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
k59_246880_1	1249627.D779_2154	1.49e-22	96.3	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales	135613|Chromatiales	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_246880_2	2340.JV46_15400	6.14e-95	291.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RR1J@1236|Gammaproteobacteria,1JBRK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	CobB/CobQ-like glutamine amidotransferase domain	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_115470_1	1165841.SULAR_03742	8.72e-198	577.0	COG3387@1|root,COG3387@2|Bacteria,1MXWR@1224|Proteobacteria	1224|Proteobacteria	G	phosphorylase kinase alphabeta	ygeQ	-	-	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_15
k59_92094_1	318161.Sden_0778	6.53e-48	162.0	COG0412@1|root,COG0412@2|Bacteria,1RD65@1224|Proteobacteria	1224|Proteobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_107555_2	1121403.AUCV01000066_gene4154	1.04e-151	440.0	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2X6QW@28221|Deltaproteobacteria,2MN97@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_69097_1	616991.JPOO01000003_gene1065	1.65e-09	64.7	COG5661@1|root,COG5661@2|Bacteria,4PN8B@976|Bacteroidetes	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239351_1	1196083.SALWKB12_0564	5.99e-27	102.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,2KRMV@206351|Neisseriales	206351|Neisseriales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_239351_2	1459636.NTE_02192	5.98e-20	89.7	COG1249@1|root,arCOG01068@2157|Archaea	2157|Archaea	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_30499_1	466088.CL42_12555	8.4e-30	120.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,3NKPX@468|Moraxellaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_22539_1	502025.Hoch_3176	3.44e-15	77.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,42ZX4@68525|delta/epsilon subdivisions,2WVHE@28221|Deltaproteobacteria,2YUT3@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_22539_2	530564.Psta_2699	2.79e-05	47.8	COG1874@1|root,COG2304@1|root,COG1874@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
k59_231250_1	102129.Lepto7375DRAFT_0843	2.94e-23	102.0	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_45801_1	10228.TriadP30101	1.58e-07	55.5	COG0664@1|root,KOG0614@2759|Eukaryota,3AH8Y@33154|Opisthokonta,3BA35@33208|Metazoa	33208|Metazoa	T	cGMP-dependent protein kinase activity	PRKG1	GO:0000166,GO:0001669,GO:0001764,GO:0003008,GO:0003012,GO:0003013,GO:0003018,GO:0003298,GO:0003300,GO:0003301,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004690,GO:0004692,GO:0005246,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0006109,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006928,GO:0006937,GO:0006940,GO:0006996,GO:0007010,GO:0007154,GO:0007162,GO:0007165,GO:0007204,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0008015,GO:0008016,GO:0008150,GO:0008152,GO:0008285,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010543,GO:0010544,GO:0010563,GO:0010565,GO:0010566,GO:0010675,GO:0010677,GO:0010817,GO:0010919,GO:0010920,GO:0010959,GO:0012505,GO:0014048,GO:0014050,GO:0014706,GO:0014896,GO:0014897,GO:0014910,GO:0014912,GO:0016020,GO:0016043,GO:0016049,GO:0016247,GO:0016301,GO:0016310,GO:0016358,GO:0016477,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019001,GO:0019216,GO:0019218,GO:0019220,GO:0019222,GO:0019538,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0019934,GO:0019935,GO:0022008,GO:0022407,GO:0022408,GO:0022898,GO:0023052,GO:0030003,GO:0030029,GO:0030030,GO:0030036,GO:0030141,GO:0030154,GO:0030155,GO:0030182,GO:0030193,GO:0030195,GO:0030334,GO:0030336,GO:0030551,GO:0030553,GO:0030900,GO:0031175,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032101,GO:0032102,GO:0032350,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0032890,GO:0032891,GO:0034110,GO:0034111,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035051,GO:0035150,GO:0035265,GO:0035296,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0042127,GO:0042311,GO:0042592,GO:0042692,GO:0042752,GO:0042753,GO:0042802,GO:0042803,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043271,GO:0043412,GO:0044057,GO:0044070,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044557,GO:0045822,GO:0045912,GO:0045932,GO:0045936,GO:0045986,GO:0046885,GO:0046890,GO:0046983,GO:0048273,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048588,GO:0048589,GO:0048660,GO:0048662,GO:0048666,GO:0048699,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050810,GO:0050818,GO:0050819,GO:0050865,GO:0050866,GO:0050878,GO:0050880,GO:0050896,GO:0051019,GO:0051046,GO:0051048,GO:0051049,GO:0051050,GO:0051051,GO:0051146,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051270,GO:0051271,GO:0051336,GO:0051480,GO:0051674,GO:0051716,GO:0051952,GO:0051953,GO:0051955,GO:0051956,GO:0055001,GO:0055002,GO:0055006,GO:0055007,GO:0055013,GO:0055017,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060087,GO:0060322,GO:0060419,GO:0060537,GO:0061041,GO:0061045,GO:0061049,GO:0061061,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0080090,GO:0080134,GO:0090066,GO:0090075,GO:0090257,GO:0090330,GO:0090331,GO:0097159,GO:0097223,GO:0097367,GO:0097708,GO:0097746,GO:0097755,GO:0098771,GO:0098772,GO:0099106,GO:0099503,GO:0120036,GO:0140096,GO:1900046,GO:1900047,GO:1901016,GO:1901018,GO:1901265,GO:1901363,GO:1901379,GO:1901381,GO:1901564,GO:1902606,GO:1902608,GO:1902930,GO:1902931,GO:1903034,GO:1903035,GO:1903522,GO:1903523,GO:1903530,GO:1903531,GO:1903792,GO:1904062,GO:1904064,GO:1904705,GO:1904706,GO:1904752,GO:1904753,GO:2000145,GO:2000146,GO:2000224,GO:2001257,GO:2001259	2.7.11.12	ko:K07376	ko04022,ko04270,ko04540,ko04611,ko04713,ko04714,ko04730,ko04740,ko04923,ko04970,map04022,map04270,map04540,map04611,map04713,map04714,map04730,map04740,map04923,map04970	M00694	-	-	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	PKcGMP_CC,Pkinase,cNMP_binding
k59_100208_1	1122132.AQYH01000002_gene1283	1.52e-129	385.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,4BAGU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_100210_1	1168034.FH5T_18845	5.93e-59	188.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
k59_231650_1	1123228.AUIH01000102_gene3067	9.39e-171	488.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,1RQQA@1236|Gammaproteobacteria,1XKYJ@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_211098_2	1123400.KB904816_gene1646	3.26e-45	154.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,46088@72273|Thiotrichales	72273|Thiotrichales	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_87281_1	1408473.JHXO01000004_gene141	1.04e-11	64.3	COG2198@1|root,COG2198@2|Bacteria,4NZRF@976|Bacteroidetes,2FZRE@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_87281_2	1408473.JHXO01000004_gene140	5.05e-08	53.5	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,2FPDM@200643|Bacteroidia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_33500_1	1123399.AQVE01000013_gene264	2.74e-76	233.0	COG4636@1|root,COG4636@2|Bacteria,1RH5Y@1224|Proteobacteria,1S823@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_141524_1	867900.Celly_2022	2.05e-40	143.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia,1F8FC@104264|Cellulophaga	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_141524_2	313596.RB2501_02865	1.81e-41	147.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1HWQM@117743|Flavobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_10148_1	1238450.VIBNISOn1_1350038	1.99e-87	262.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,1XXW0@135623|Vibrionales	135623|Vibrionales	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
k59_195767_1	1294273.roselon_01289	5.85e-73	224.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,2TTCR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Protein conserved in bacteria	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF900,Sel1
k59_133749_1	1165841.SULAR_05898	2.55e-114	358.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_172518_1	400668.Mmwyl1_1424	2.26e-24	106.0	COG0591@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XH3H@135619|Oceanospirillales	135619|Oceanospirillales	T	COG0591 Na proline symporter	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF
k59_164823_1	1168034.FH5T_12060	2.39e-43	153.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,2FNB6@200643|Bacteroidia	976|Bacteroidetes	P	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_164823_2	1168034.FH5T_12065	4.27e-19	85.9	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia	976|Bacteroidetes	E	Xaa-His dipeptidase	pepD_2	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_126209_1	1232410.KI421428_gene1170	2.09e-98	302.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,43TYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_149148_3	1292034.OR37_01404	4.39e-52	169.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2KGMZ@204458|Caulobacterales	204458|Caulobacterales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_211105_1	472759.Nhal_3495	5.41e-75	239.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1WZJC@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_164825_1	378753.KRH_10030	3.66e-08	55.5	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,1W7MW@1268|Micrococcaceae	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_156945_1	1128427.KB904821_gene1848	7.98e-19	87.8	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
k59_79695_1	870187.Thini_0186	3.87e-39	135.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,4604J@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
k59_79695_2	870187.Thini_0187	2.26e-79	240.0	COG2878@1|root,COG2878@2|Bacteria,1RE44@1224|Proteobacteria,1S5MU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_79695_3	631362.Thi970DRAFT_03640	2.21e-21	93.2	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWWZ@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
k59_10158_1	1165841.SULAR_07885	5.17e-56	174.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2YPSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Nitrogen fixation protein NifU	-	-	-	-	-	-	-	-	-	-	-	-	NifU
k59_10158_2	387093.SUN_2286	1.06e-37	131.0	2AJZN@1|root,31ANZ@2|Bacteria,1Q5WH@1224|Proteobacteria,42UJ4@68525|delta/epsilon subdivisions,2YPXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41076_1	641526.ADIWIN_2654	6.09e-59	192.0	COG0491@1|root,COG0491@2|Bacteria,4NJZR@976|Bacteroidetes,1HZBW@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_25502_1	1165841.SULAR_10314	3.72e-59	191.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2YMXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_10167_1	2340.JV46_13510	6.54e-60	192.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S9PP@1236|Gammaproteobacteria,1J6J0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_95170_1	1328313.DS2_08605	3.55e-63	221.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465AJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_156965_1	387093.SUN_2219	7.27e-98	298.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_2426_1	396588.Tgr7_0954	8.36e-36	132.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1WXQH@135613|Chromatiales	135613|Chromatiales	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_102781_1	1250005.PHEL85_2141	7.11e-73	240.0	COG0243@1|root,COG0243@2|Bacteria,4PIKC@976|Bacteroidetes,1ICDV@117743|Flavobacteriia,3VXCJ@52959|Polaribacter	976|Bacteroidetes	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_226563_2	313596.RB2501_00131	5.35e-50	166.0	COG1629@1|root,COG1629@2|Bacteria,4PKUT@976|Bacteroidetes,1IJFW@117743|Flavobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_102782_1	1168034.FH5T_08855	1.05e-95	292.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,2FM4A@200643|Bacteroidia	976|Bacteroidetes	MU	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_141571_1	1165841.SULAR_01350	9.72e-133	402.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_71806_1	857087.Metme_3102	9.47e-15	69.3	2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,1S999@1236|Gammaproteobacteria,1XFWV@135618|Methylococcales	135618|Methylococcales	S	May protect the nitrogenase Fe-Mo protein from oxidative damage	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_25516_1	121225.PHUM136490-PA	4.12e-09	63.9	COG0554@1|root,KOG2517@2759|Eukaryota,38DGY@33154|Opisthokonta,3B9PY@33208|Metazoa,3CVSP@33213|Bilateria,41VT7@6656|Arthropoda,3SGKN@50557|Insecta,3EC6C@33342|Paraneoptera	33208|Metazoa	G	FGGY family of carbohydrate kinases, C-terminal domain	GK	GO:0003674,GO:0003824,GO:0004370,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0005975,GO:0006066,GO:0006071,GO:0006072,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009636,GO:0009987,GO:0010033,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019400,GO:0019432,GO:0019637,GO:0019751,GO:0019867,GO:0031090,GO:0031323,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0033500,GO:0042221,GO:0042393,GO:0042493,GO:0042592,GO:0042593,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0045471,GO:0046167,GO:0046460,GO:0046463,GO:0046486,GO:0046677,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0052646,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090407,GO:0097305,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901576,GO:1901615,GO:1901700	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_203440_1	1198232.CYCME_1039	1.41e-47	172.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,4624G@72273|Thiotrichales	72273|Thiotrichales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014,ko:K16089,ko:K19611	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	1.B.14,1.B.14.1,1.B.14.1.22,1.B.14.1.3,1.B.14.1.5,1.B.14.10	-	-	Plug,TonB_dep_Rec
k59_195789_2	562970.Btus_1636	9.11e-26	104.0	COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,2785R@186823|Alicyclobacillaceae	91061|Bacilli	Q	homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
k59_180325_1	1121920.AUAU01000002_gene2032	2.31e-68	225.0	COG2256@1|root,COG2256@2|Bacteria,3Y3F7@57723|Acidobacteria	57723|Acidobacteria	L	AAA ATPase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_17608_2	4572.TRIUR3_00337-P1	2.4e-100	291.0	COG0049@1|root,KOG3291@2759|Eukaryota,37YX8@33090|Viridiplantae,3GNS6@35493|Streptophyta,3KTYP@4447|Liliopsida,3IAPX@38820|Poales	35493|Streptophyta	J	ribosomal protein S7	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S7
k59_17608_3	4155.Migut.F01470.1.p	8.91e-217	598.0	COG1007@1|root,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,44UT6@71274|asterids	35493|Streptophyta	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K05573	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M
k59_17608_4	3880.AES69829	3.57e-109	338.0	COG0048@1|root,COG0049@1|root,COG1007@1|root,KOG1750@2759|Eukaryota,KOG3291@2759|Eukaryota,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,4JNJF@91835|fabids	35493|Streptophyta	C	NAD(P)H-quinone oxidoreductase subunit 2	ndhB	-	1.6.5.3	ko:K02992,ko:K05573	ko00190,ko01100,ko03010,map00190,map01100,map03010	M00145,M00178,M00179	R11945	RC00061	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	Proton_antipo_M
k59_149173_1	1300345.LF41_2649	3.08e-25	110.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales	135614|Xanthomonadales	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_126228_2	263358.VAB18032_06195	1.66e-09	62.4	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,4DAU0@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigL	GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_156977_1	981085.XP_010096025.1	1.06e-10	61.2	COG2940@1|root,KOG1082@2759|Eukaryota,37IV0@33090|Viridiplantae,3G9R9@35493|Streptophyta,4JMDI@91835|fabids	35493|Streptophyta	B	histone-lysine N-methyltransferase, H3 lysine-9 specific	-	GO:0000166,GO:0000775,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006325,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008327,GO:0008757,GO:0009987,GO:0010216,GO:0010385,GO:0010428,GO:0010429,GO:0016043,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0034641,GO:0034968,GO:0036094,GO:0036211,GO:0042054,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046974,GO:0051276,GO:0051567,GO:0061647,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0098687,GO:0140096,GO:1901265,GO:1901360,GO:1901363,GO:1901564	2.1.1.43	ko:K11420	ko00310,ko04211,map00310,map04211	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	Pre-SET,SAD_SRA,SET
k59_87308_1	485918.Cpin_5191	1.13e-47	176.0	COG1020@1|root,COG1020@2|Bacteria,4NGU4@976|Bacteroidetes,1J06C@117747|Sphingobacteriia	976|Bacteroidetes	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_102795_1	2340.JV46_11980	4.18e-96	295.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1J4Q1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_41106_1	1165841.SULAR_05588	9.1e-53	181.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_149175_1	1151292.QEW_1837	3.79e-39	150.0	COG0450@1|root,COG3325@1|root,COG0450@2|Bacteria,COG3325@2|Bacteria,1UPJ7@1239|Firmicutes,24D95@186801|Clostridia,25UFM@186804|Peptostreptococcaceae	186801|Clostridia	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	1-cysPrx_C,AhpC-TSA,Dockerin_1,Glyco_hydro_18
k59_41107_1	270374.MELB17_23670	3e-29	118.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,465H4@72275|Alteromonadaceae	1236|Gammaproteobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_188031_2	1168034.FH5T_19605	4.37e-75	234.0	2C57D@1|root,2Z7RS@2|Bacteria,4NEKN@976|Bacteroidetes,2FR8H@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
k59_41108_1	1168034.FH5T_12470	3.06e-55	193.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,2FMM3@200643|Bacteroidia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
k59_149181_1	1279019.ARQK01000031_gene1201	3.85e-25	108.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_218991_1	1380394.JADL01000006_gene5258	7.11e-32	121.0	28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,2JXPF@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56429_1	314275.MADE_000001022525	2.43e-26	119.0	COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Psort location Cytoplasmic, score	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	Prim-Pol,Toprim_3,Toprim_4
k59_110858_1	85929.N1QNH3	1.39e-19	96.7	COG0688@1|root,KOG1032@1|root,KOG1032@2759|Eukaryota,KOG2419@2759|Eukaryota,38CUE@33154|Opisthokonta,3NVAR@4751|Fungi,3QMR5@4890|Ascomycota,1ZXGI@147541|Dothideomycetes,3MHGN@451867|Dothideomycetidae	4751|Fungi	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine	PSD2	GO:0000139,GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003674,GO:0003824,GO:0004609,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005773,GO:0005774,GO:0005794,GO:0006575,GO:0006629,GO:0006644,GO:0006646,GO:0006650,GO:0006656,GO:0006658,GO:0006659,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0012505,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0019637,GO:0030447,GO:0031090,GO:0031410,GO:0031667,GO:0031982,GO:0031984,GO:0036170,GO:0036171,GO:0036180,GO:0040007,GO:0042221,GO:0042398,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046337,GO:0046470,GO:0046474,GO:0046486,GO:0050896,GO:0071704,GO:0090407,GO:0097164,GO:0097708,GO:0098588,GO:0098791,GO:0098805,GO:0098852,GO:1901564,GO:1901566,GO:1901576	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	C2,PS_Dcarbxylase
k59_242413_1	1121875.KB907551_gene1175	9.23e-73	231.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HZHR@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_165187_1	395493.BegalDRAFT_2006	9.78e-99	299.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,45ZT0@72273|Thiotrichales	72273|Thiotrichales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_95492_1	313596.RB2501_02685	3.33e-167	478.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,1HWX3@117743|Flavobacteriia	976|Bacteroidetes	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_2691_1	1168034.FH5T_01435	4.04e-97	288.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_221568_1	1168034.FH5T_10515	2.18e-113	346.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_190728_1	1026882.MAMP_00785	5.77e-06	52.4	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales	72273|Thiotrichales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_159643_1	1122915.AUGY01000205_gene1111	5.4e-13	75.5	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
k59_121295_1	90814.KL370892_gene2146	6.82e-46	167.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales	72273|Thiotrichales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_66979_1	1304885.AUEY01000009_gene1949	1.7e-111	332.0	COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,43CQR@68525|delta/epsilon subdivisions,2X7Y7@28221|Deltaproteobacteria,2MPPF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_97819_1	439481.Aboo_0621	2.37e-104	318.0	COG0436@1|root,arCOG01130@2157|Archaea,2Y6Z4@28890|Euryarchaeota,3F2YP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	PFAM Aminotransferase class I and II	-	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_213861_1	981383.AEWH01000050_gene116	9.35e-14	71.2	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHGJ@91061|Bacilli	91061|Bacilli	T	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_174958_2	673835.D2IZE0_9CAUD	2.67e-18	85.1	4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses  no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae	10699|Siphoviridae	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_190738_1	1123057.P872_13075	6.7e-27	105.0	COG4122@1|root,COG4122@2|Bacteria,4PBU1@976|Bacteroidetes,47WBZ@768503|Cytophagia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
k59_190738_2	388413.ALPR1_18048	4.96e-09	57.4	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_213867_2	595460.RRSWK_01592	4.39e-29	109.0	COG3296@1|root,COG3296@2|Bacteria,2J145@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870,SHOCT
k59_121305_1	1046724.KB889886_gene536	8.68e-05	43.5	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,1S4EZ@1236|Gammaproteobacteria,46B1C@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	paaI	GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_1225,iEC55989_1330.EC55989_1532,iECDH10B_1368.ECDH10B_1521,iECDH1ME8569_1439.EcDH1_2249,iECIAI1_1343.ECIAI1_1396,iECO103_1326.ECO103_1533,iECO111_1330.ECO111_1790,iECO26_1355.ECO26_2000,iECSE_1348.ECSE_1481,iEKO11_1354.EKO11_2417,iETEC_1333.ETEC_1471,iEcDH1_1363.EcDH1_2249,iEcE24377_1341.EcE24377A_1581,iEcHS_1320.EcHS_A1483,iEcolC_1368.EcolC_2259,iUMNK88_1353.UMNK88_1803,iY75_1357.Y75_RS07340	4HBT
k59_121305_2	693444.D782_2322	1.91e-61	201.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0047475,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iECIAI1_1343.ECIAI1_1398,iECO111_1330.ECO111_1792,iECO26_1355.ECO26_2002,iECSE_1348.ECSE_1483,iECW_1372.ECW_m1532,iEKO11_1354.EKO11_2415,iEcE24377_1341.EcE24377A_1584,iWFL_1372.ECW_m1532	AMP-binding,AMP-binding_C_2
k59_198584_2	944547.ABLL_2828	3.43e-50	166.0	COG3907@1|root,COG3907@2|Bacteria,1MY7B@1224|Proteobacteria,42RAC@68525|delta/epsilon subdivisions,2YRS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_82290_2	1121937.AUHJ01000005_gene2262	6.82e-66	219.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4647U@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_121312_1	1165841.SULAR_03317	7.26e-95	301.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_97837_1	762376.AXYL_04134	3.33e-16	72.4	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,3T4GC@506|Alcaligenaceae	28216|Betaproteobacteria	K	cold-shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_97837_2	2340.JV46_14480	4.2e-53	178.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1J4Z7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Isocitrate	icd	GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
k59_174974_1	1123401.JHYQ01000024_gene1298	6.53e-76	238.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,461RJ@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_159666_1	1196028.ALEF01000006_gene3214	0.000103	43.5	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,4C4ID@84406|Virgibacillus	91061|Bacilli	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_159666_2	1403313.AXBR01000021_gene3084	2.31e-49	171.0	COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus	91061|Bacilli	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_20153_2	710686.Mycsm_01635	1.31e-79	256.0	COG0346@1|root,COG0346@2|Bacteria,2IP2W@201174|Actinobacteria,23B6D@1762|Mycobacteriaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4,Polyketide_cyc2
k59_5091_1	870187.Thini_3579	1.5e-25	99.4	COG3385@1|root,COG3385@2|Bacteria,1NIWM@1224|Proteobacteria,1S5FT@1236|Gammaproteobacteria,462IG@72273|Thiotrichales	72273|Thiotrichales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_105363_2	1165841.SULAR_06113	4.55e-58	180.0	COG1605@1|root,COG1605@2|Bacteria,1N6UE@1224|Proteobacteria,42UUU@68525|delta/epsilon subdivisions,2YQ49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
k59_113240_1	448385.sce7823	3.65e-19	87.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42R0K@68525|delta/epsilon subdivisions,2WMTU@28221|Deltaproteobacteria,2Z309@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_5094_1	251229.Chro_3030	7.8e-37	145.0	COG0515@1|root,COG0642@1|root,COG0784@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,3VI2Q@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_206050_1	243090.RB3967	7.97e-50	175.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_190759_1	395493.BegalDRAFT_2469	3.4e-103	323.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_174979_1	754477.Q7C_464	2.51e-83	259.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46046@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_82299_2	1540097.A0A0A0YRP0_9CAUD	9.59e-23	98.6	4QEFX@10239|Viruses,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_51265_1	335543.Sfum_2600	2.48e-95	292.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_182961_1	385682.AFSL01000072_gene1345	3.76e-45	163.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4N@976|Bacteroidetes,2G2S8@200643|Bacteroidia	976|Bacteroidetes	C	K00162 pyruvate dehydrogenase E1 component subunit beta	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_182961_2	351627.Csac_0873	3.27e-19	88.2	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,42EWF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_206053_1	1333998.M2A_1527	2.35e-74	226.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,4BQ9X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_167700_1	395493.BegalDRAFT_0091	1.75e-114	350.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_113252_1	1123368.AUIS01000007_gene2681	4.88e-101	318.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,2NCDM@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_51268_1	1165841.SULAR_04267	1.75e-103	311.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_159688_1	1297742.A176_02133	7.23e-34	132.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,437G4@68525|delta/epsilon subdivisions,2X2NQ@28221|Deltaproteobacteria,2YUKF@29|Myxococcales	28221|Deltaproteobacteria	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
k59_12604_1	1165841.SULAR_00230	3.96e-23	100.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_12604_2	1165841.SULAR_00225	2.57e-08	53.1	COG0212@1|root,COG0212@2|Bacteria,1RDZJ@1224|Proteobacteria,42SXM@68525|delta/epsilon subdivisions,2YPJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_74633_1	1123393.KB891316_gene1430	4.55e-119	357.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria,1KSNX@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_74633_2	2340.JV46_06990	3.65e-08	53.5	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1J8NG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k59_20169_1	240015.ACP_1196	1.08e-198	564.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_36137_1	377629.TERTU_1671	2.8e-19	83.6	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,2PPX7@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_36137_2	377629.TERTU_1672	6.19e-35	125.0	COG0848@1|root,COG0848@2|Bacteria,1NXRD@1224|Proteobacteria,1SQ9G@1236|Gammaproteobacteria,2PPMK@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_128881_1	313595.P700755_002781	8.96e-76	251.0	COG3385@1|root,COG3385@2|Bacteria,4NKTU@976|Bacteroidetes,1I7NH@117743|Flavobacteriia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_121353_1	1042163.BRLA_c025650	1.26e-30	128.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K15662	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_67036_1	1121405.dsmv_3645	2.79e-67	229.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_20442_1	1121405.dsmv_0406	1.17e-28	110.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MIAE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_20442_2	439235.Dalk_2649	3.22e-30	116.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHW4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_59387_1	1042163.BRLA_c034120	6.57e-11	67.4	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,26QE7@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
k59_82499_1	1168034.FH5T_16520	7.58e-104	313.0	COG3547@1|root,COG3547@2|Bacteria,4NHYP@976|Bacteroidetes,2FKYS@200643|Bacteroidia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_67303_1	1026882.MAMP_00066	1.8e-31	117.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,4619W@72273|Thiotrichales	72273|Thiotrichales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k59_67303_2	161934.XP_010675785.1	5.18e-20	88.6	COG0129@1|root,KOG2448@2759|Eukaryota,37R9I@33090|Viridiplantae,3GBHF@35493|Streptophyta	35493|Streptophyta	E	Dihydroxy-acid dehydratase	-	GO:0003674,GO:0003824,GO:0004160,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009507,GO:0009532,GO:0009536,GO:0009553,GO:0009555,GO:0009570,GO:0009628,GO:0009651,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0022622,GO:0032501,GO:0032502,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0050896,GO:0071704,GO:0099402,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_237420_1	1260251.SPISAL_04745	2.52e-36	125.0	COG3093@1|root,COG3093@2|Bacteria,1N2BD@1224|Proteobacteria,1S8Z4@1236|Gammaproteobacteria,1WZ50@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k59_237420_2	1537994.JQFW01000007_gene2865	4.09e-43	142.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,1S9CP@1236|Gammaproteobacteria,467U0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
k59_183304_1	247634.GPB2148_2770	8.99e-118	358.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_214160_1	1192034.CAP_0448	2.65e-11	72.0	COG0457@1|root,COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YU18@29|Myxococcales	28221|Deltaproteobacteria	KLT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,Pkinase
k59_28439_1	1049564.TevJSym_ai00070	2.11e-71	234.0	COG3291@1|root,COG3291@2|Bacteria,1R5MQ@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c5530 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152207_1	525897.Dbac_2636	1.58e-25	109.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2WJGZ@28221|Deltaproteobacteria,2M9Y5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_90183_1	1165841.SULAR_02488	1.78e-27	108.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42USK@68525|delta/epsilon subdivisions,2YPZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_90183_2	1165841.SULAR_02493	1.59e-19	85.1	2AK26@1|root,31ART@2|Bacteria,1Q60M@1224|Proteobacteria,432MI@68525|delta/epsilon subdivisions,2YSKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_77646_1	748658.KB907318_gene1012	1.84e-30	119.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RYYZ@1236|Gammaproteobacteria,1WZQD@135613|Chromatiales	135613|Chromatiales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
k59_77646_2	1026882.MAMP_02916	1.73e-34	129.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,4610E@72273|Thiotrichales	72273|Thiotrichales	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_93241_2	1165841.SULAR_02333	2.8e-54	187.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GGDEF,PAS_9,dCache_3
k59_54513_1	1150398.JIBJ01000002_gene1344	9.81e-84	267.0	COG1080@1|root,COG1080@2|Bacteria,2IA7T@201174|Actinobacteria,1WAG8@1268|Micrococcaceae	201174|Actinobacteria	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_201460_1	1509403.GW12_00720	4.29e-06	55.1	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S0WX@1236|Gammaproteobacteria,3NK4C@468|Moraxellaceae	1236|Gammaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
k59_131849_1	1168034.FH5T_12310	2.38e-103	319.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,2FMC9@200643|Bacteroidia	976|Bacteroidetes	S	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_8090_1	1296416.JACB01000060_gene5303	6.14e-85	261.0	COG2819@1|root,COG2819@2|Bacteria,4NI0I@976|Bacteroidetes,1IA3U@117743|Flavobacteriia,2YK55@290174|Aquimarina	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Esterase
k59_155063_1	1385515.N791_13720	1.4e-46	162.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S2K0@1236|Gammaproteobacteria,1X321@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_155063_2	648885.KB316282_gene1880	1.75e-19	86.7	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,1JVBU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN2	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k59_31417_1	999141.GME_08244	8.72e-90	280.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XHYA@135619|Oceanospirillales	135619|Oceanospirillales	K	containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_232434_2	3641.EOY05821	1.83e-11	68.2	KOG1075@1|root,KOG1075@2759|Eukaryota,37ZQ4@33090|Viridiplantae,3GK8S@35493|Streptophyta	35493|Streptophyta	S	Domain of unknown function (DUF4283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,zf-CCHC_4
k59_46697_1	155515.JP36_05145	3.28e-08	58.9	COG3676@1|root,COG3676@2|Bacteria,1R7ZF@1224|Proteobacteria,1S6YQ@1236|Gammaproteobacteria,1Y7XM@135625|Pasteurellales	135625|Pasteurellales	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
k59_240148_1	1283300.ATXB01000001_gene2477	1.85e-56	181.0	COG3415@1|root,COG3415@2|Bacteria,1QVAE@1224|Proteobacteria,1T533@1236|Gammaproteobacteria,1XGNF@135618|Methylococcales	135618|Methylococcales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_240148_2	1283300.ATXB01000001_gene2476	2.77e-110	322.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_201466_2	1116472.MGMO_92c00370	2.03e-11	65.1	COG0642@1|root,COG2205@2|Bacteria,1QVTG@1224|Proteobacteria,1T4N1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
k59_8096_1	1265505.ATUG01000002_gene1684	1.29e-11	63.9	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42Q4I@68525|delta/epsilon subdivisions,2WIX3@28221|Deltaproteobacteria,2MIWV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-III	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_8096_2	1282361.ABAC402_18500	1e-27	112.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2TRAK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_77650_1	313596.RB2501_08040	7.88e-111	327.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1HX6M@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_217000_1	768671.ThimaDRAFT_2890	6.96e-109	336.0	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales	135613|Chromatiales	M	HAD-superfamily hydrolase, subfamily IIB	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
k59_131855_1	1097668.BYI23_A013890	6.62e-16	75.9	COG0179@1|root,COG0179@2|Bacteria,1QUQP@1224|Proteobacteria,2VQEI@28216|Betaproteobacteria,1K1V4@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
k59_116365_1	314278.NB231_13276	3.59e-51	172.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_116365_2	1268635.Loa_02269	7.71e-10	59.7	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1JCV7@118969|Legionellales	118969|Legionellales	NU	Type II/IV secretion system protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_85440_1	1167006.UWK_01314	1.2e-63	208.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,42M4U@68525|delta/epsilon subdivisions,2WJAG@28221|Deltaproteobacteria,2MQ1H@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Permease family	-	-	-	ko:K03458,ko:K16345	-	-	-	-	ko00000,ko02000	2.A.40,2.A.40.4.2	-	-	Xan_ur_permease
k59_178291_1	697282.Mettu_0993	1.47e-156	450.0	COG3385@1|root,COG3385@2|Bacteria,1NIWM@1224|Proteobacteria,1S5FT@1236|Gammaproteobacteria,1XFX0@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_139678_1	396014.BF93_09160	4.81e-24	100.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FBUG@85020|Dermabacteraceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	aldA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K00138,ko:K18370	ko00010,ko00620,ko00640,ko01100,ko01110,ko01120,map00010,map00620,map00640,map01100,map01110,map01120	-	R00711,R10703	RC00047,RC00545	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_31426_2	1173029.JH980292_gene1155	1.32e-08	53.5	COG1487@1|root,COG1487@2|Bacteria,1G6RD@1117|Cyanobacteria,1HBT9@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
k59_100923_1	104623.Ser39006_01580	4.32e-24	106.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,402EW@613|Serratia	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_193721_1	28072.Nos7524_1682	7.63e-30	125.0	COG2303@1|root,COG2303@2|Bacteria,1G5DG@1117|Cyanobacteria,1HRGW@1161|Nostocales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_240152_2	1288079.AUKN01000010_gene2065	2.34e-11	63.5	COG0331@1|root,COG2070@1|root,COG3321@1|root,COG0331@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,2GR80@201174|Actinobacteria	201174|Actinobacteria	I	2-nitropropane dioxygenase	-	-	-	ko:K15329	-	-	-	-	ko00000,ko01008	-	-	-	Acyl_transf_1,NMO
k59_186016_1	555779.Dthio_PD2605	6.86e-35	137.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_100924_1	2340.JV46_24540	1.84e-21	92.4	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1J4ZG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iJN746.PP_0110	UbiA
k59_240156_1	566466.NOR53_3227	1.18e-63	210.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,1J804@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_93277_1	977880.RALTA_A2587	1.59e-10	61.2	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,1JZW6@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_93277_2	706191.PANA_3128	6.31e-20	89.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,3VZIR@53335|Pantoea	1236|Gammaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_170593_1	1165841.SULAR_09059	1.34e-132	385.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_116381_1	2340.JV46_06250	1.76e-30	112.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1J60R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
k59_116381_2	1384056.N787_01450	3.59e-29	110.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1X631@135614|Xanthomonadales	135614|Xanthomonadales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k59_162752_1	232346.JHQL01000001_gene2054	1.11e-78	255.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XI30@135619|Oceanospirillales	135619|Oceanospirillales	I	Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_116384_1	1165841.SULAR_03657	2.52e-88	281.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_232458_1	861299.J421_0276	7.76e-43	157.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_8
k59_155106_1	1165841.SULAR_09039	5.25e-107	317.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_155106_2	1165841.SULAR_09044	3.73e-101	298.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42Y2B@68525|delta/epsilon subdivisions,2YT6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane protein, required for colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_155106_3	1165841.SULAR_09049	1.32e-29	108.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2YPGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	fur	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_147293_1	1163617.SCD_n00574	3.33e-27	114.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria	28216|Betaproteobacteria	U	AAA domain	exeA1	-	-	-	-	-	-	-	-	-	-	-	AAA_22,SPOR
k59_8126_1	349124.Hhal_1259	2.6e-55	181.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1WWNN@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	-	-	2.4.2.28,2.4.2.44	ko:K00772,ko:K19696	ko00270,ko01100,map00270,map01100	M00034	R01402,R09668	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_178784_1	314230.DSM3645_16345	2.67e-51	178.0	COG0168@1|root,COG0168@2|Bacteria,2IYFA@203682|Planctomycetes	203682|Planctomycetes	P	COG0168 Trk-type K transport systems, membrane components	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_155539_1	760192.Halhy_3230	1.95e-32	127.0	COG3039@1|root,COG3039@2|Bacteria,4NI06@976|Bacteroidetes,1IT64@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_47228_1	1122931.AUAE01000001_gene619	2.27e-87	266.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
k59_85911_1	709032.Sulku_1756	2.08e-50	182.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_62650_1	234267.Acid_7040	3.02e-20	92.4	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria	57723|Acidobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_101366_1	573.JG24_12135	2.42e-124	367.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1S0KW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Molecular chaperone GroES	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_240543_1	1168034.FH5T_07860	9.41e-106	318.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,2FP2X@200643|Bacteroidia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_101367_1	1123326.JFBL01000012_gene102	1.08e-88	270.0	COG0687@1|root,COG0687@2|Bacteria,1MU12@1224|Proteobacteria,42NHM@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	extracellular solute-binding protein, family 1	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k59_140156_1	1165841.SULAR_06578	9.55e-103	315.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_147749_1	388413.ALPR1_21088	1.63e-69	239.0	COG1361@1|root,COG3210@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11
k59_194135_1	313596.RB2501_06520	4.4e-08	54.7	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	-	-	-	ko:K08309,ko:K11935,ko:K20543	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01011,ko02000	1.B.55.3	GH23	-	BCSC_C,TPR_12,TPR_16,TPR_19,TPR_6,TPR_8
k59_194135_2	1416760.AYMS01000002_gene1856	1.08e-60	190.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia,47I5C@76831|Myroides	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_23955_1	316058.RPB_2356	0.000998	47.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQTN@28211|Alphaproteobacteria,3JRHF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	MA20_35625	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8
k59_47251_1	1122201.AUAZ01000014_gene214	7.28e-34	124.0	COG0546@1|root,COG0546@2|Bacteria,1RHAA@1224|Proteobacteria,1S67H@1236|Gammaproteobacteria,46DH9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
k59_55026_1	572477.Alvin_0495	9.93e-158	454.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1WWNX@135613|Chromatiales	135613|Chromatiales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_31861_2	435908.IDSA_11345	2.56e-35	135.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QGPX@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_3,PAS_4
k59_116909_1	575540.Isop_1175	2.22e-96	290.0	2C3PP@1|root,2Z954@2|Bacteria,2J2AE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194145_1	387093.SUN_2408	1.5e-13	72.4	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2YNPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_163265_1	765911.Thivi_1899	1.99e-46	163.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1WWE4@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23
k59_78138_1	1165841.SULAR_02428	1.47e-45	152.0	COG4902@1|root,COG4902@2|Bacteria	2|Bacteria	-	-	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	DUF2202
k59_19103_1	2340.JV46_07090	3.58e-117	348.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1J4IG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_19103_2	555778.Hneap_1244	4.73e-25	102.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_243683_1	1121405.dsmv_2856	5.25e-186	540.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11689_2	1049564.TevJSym_ab01990	1.41e-35	126.0	COG0636@1|root,COG0636@2|Bacteria,1REA9@1224|Proteobacteria,1S51I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
k59_104334_1	373994.Riv7116_1317	0.000122	43.9	COG2072@1|root,COG2072@2|Bacteria,1G4SA@1117|Cyanobacteria,1HRUV@1161|Nostocales	1117|Cyanobacteria	P	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
k59_120061_1	1168034.FH5T_17085	6.49e-83	257.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,2FS1D@200643|Bacteroidia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_57961_1	349521.HCH_00974	3.08e-73	231.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XI6J@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_88966_1	1177179.A11A3_17167	3.09e-120	350.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1XNN8@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_158605_1	156889.Mmc1_2882	2.06e-56	207.0	COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,2U67V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	TIGRFAM phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_135374_1	1165841.SULAR_09114	1.69e-94	281.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_96733_1	385682.AFSL01000041_gene300	4.2e-23	92.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,2FN4T@200643|Bacteroidia,3XJBJ@558415|Marinilabiliaceae	976|Bacteroidetes	P	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_96733_2	1168034.FH5T_12095	3.01e-45	162.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,2FMEE@200643|Bacteroidia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_243691_1	1168034.FH5T_12915	7.89e-49	167.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_243691_2	1168034.FH5T_12920	2.36e-42	138.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,2FTSU@200643|Bacteroidia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_158615_1	426114.THI_3653	9.78e-75	231.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VIXS@28216|Betaproteobacteria,1KNH5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28	ko:K00034,ko:K00046,ko:K00059,ko:K00216	ko00030,ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01120,map01130,map01200,map01212	M00083,M00572	R01505,R01520,R01521,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117,RC00534	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_88972_1	1165841.SULAR_08232	1.69e-142	413.0	COG3203@1|root,COG3203@2|Bacteria,1R1K3@1224|Proteobacteria,43DCJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_65741_1	1165841.SULAR_01683	4.06e-100	291.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2YNVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1038	DHquinase_II
k59_65741_2	1165841.SULAR_01688	1.81e-21	90.9	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_104349_1	1280946.HY29_15930	1.64e-30	118.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,43WQ9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Cysteine synthase	cysB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_65743_1	391587.KAOT1_06162	1.48e-64	212.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_181992_1	768671.ThimaDRAFT_3757	9.47e-46	164.0	COG0421@1|root,COG0421@2|Bacteria,1QZ2Z@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_158618_1	318167.Sfri_1239	1.14e-37	144.0	COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_65754_2	670292.JH26_14980	7.04e-12	71.2	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria,1JSWQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_158621_2	1041826.FCOL_13515	1.73e-71	222.0	COG3335@1|root,COG3335@2|Bacteria,4NR21@976|Bacteroidetes,1I35Q@117743|Flavobacteriia	976|Bacteroidetes	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_120085_1	1168034.FH5T_03850	2.1e-80	262.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_127883_1	535289.Dtpsy_0058	7.66e-47	152.0	COG3512@1|root,COG3512@2|Bacteria,1N08B@1224|Proteobacteria,2VTET@28216|Betaproteobacteria,4AHR8@80864|Comamonadaceae	28216|Betaproteobacteria	L	CRISPR associated protein Cas2	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
k59_127883_2	535289.Dtpsy_0059	9.15e-62	199.0	COG1518@1|root,COG1518@2|Bacteria,1MX9W@1224|Proteobacteria,2VNWK@28216|Betaproteobacteria,4ACAR@80864|Comamonadaceae	28216|Betaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k59_50250_1	90814.KL370891_gene1084	5.48e-40	136.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,46162@72273|Thiotrichales	72273|Thiotrichales	P	arsenate reductase	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_151146_1	402777.KB235898_gene5728	8.72e-91	297.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HEH0@1150|Oscillatoriales	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_35368_1	519989.ECTPHS_12515	8.96e-23	97.8	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales	135613|Chromatiales	I	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_35368_2	454957.IA64_13370	1.63e-24	103.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1X486@135614|Xanthomonadales	135614|Xanthomonadales	I	3-hydroxyacyl-coa dehydrogenase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_35369_1	869213.JCM21142_93870	1.69e-27	115.0	COG1470@1|root,COG1470@2|Bacteria,4NGFF@976|Bacteroidetes,47T30@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_236458_1	646529.Desaci_2454	1.18e-08	63.5	COG3039@1|root,COG3039@2|Bacteria,1TS6Q@1239|Firmicutes,24B6I@186801|Clostridia,260JJ@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_81709_1	1165841.SULAR_02023	9.22e-68	207.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,42TC4@68525|delta/epsilon subdivisions,2YPRJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_89277_1	1165841.SULAR_07500	2.03e-36	135.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_89277_2	1165841.SULAR_07505	1.11e-26	99.4	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42VNG@68525|delta/epsilon subdivisions,2YQ9F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_81712_1	1168034.FH5T_04105	2.54e-97	290.0	COG0697@1|root,COG0697@2|Bacteria,4NIBF@976|Bacteroidetes,2FR06@200643|Bacteroidia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_66174_1	1396141.BATP01000058_gene1994	9.04e-52	179.0	COG0740@1|root,COG0740@2|Bacteria,46TG6@74201|Verrucomicrobia,2IVJV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	OU	Clp protease	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
k59_166969_1	935863.AWZR01000005_gene2439	1.02e-64	214.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Activates fatty acids by binding to coenzyme A	rpfB	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_189982_1	3641.EOX92755	2.05e-13	70.1	COG2801@1|root,KOG0017@2759|Eukaryota,37ZQQ@33090|Viridiplantae,3GPET@35493|Streptophyta	35493|Streptophyta	L	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2
k59_189982_2	225117.XP_009335215.1	1.48e-60	210.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae,3GBWZ@35493|Streptophyta,4JT11@91835|fabids	35493|Streptophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve
k59_189982_3	225117.XP_009335215.1	3.13e-21	94.7	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae,3GBWZ@35493|Streptophyta,4JT11@91835|fabids	35493|Streptophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve
k59_19492_1	87626.PTD2_18160	8.22e-97	293.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,2PZF7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_66177_1	555088.DealDRAFT_2804	7.32e-82	267.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia	186801|Clostridia	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_228544_1	983544.Lacal_2170	2.87e-54	172.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_166975_1	203122.Sde_2049	2.35e-13	77.0	COG5184@1|root,COG5276@1|root,COG5644@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5644@2|Bacteria,1QX03@1224|Proteobacteria,1T31Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
k59_19497_1	1121382.JQKG01000011_gene575	5.08e-57	197.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1WJ6X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
k59_81715_1	1454004.AW11_00918	1.35e-70	225.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VMDU@28216|Betaproteobacteria	28216|Betaproteobacteria	L	RNA-directed DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_112647_1	376733.IT41_19665	2.63e-55	186.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,2PXXE@265|Paracoccus	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_19499_1	243231.GSU1950	4.7e-59	197.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria,43VMS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glycos_transf_2
k59_58341_1	713586.KB900536_gene2920	1.16e-64	204.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1WWK4@135613|Chromatiales	135613|Chromatiales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_220959_1	95619.PM1_0222460	2.09e-32	125.0	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_81728_2	218851.Aquca_023_00075.1	2.67e-83	260.0	COG1008@1|root,KOG4845@2759|Eukaryota,37KP8@33090|Viridiplantae,3GEAS@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	nad4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03881	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_153119_2	661478.OP10G_1239	4.62e-26	101.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
k59_106614_1	572480.Arnit_2925	9.17e-77	240.0	COG2605@1|root,COG2605@2|Bacteria,1QW1A@1224|Proteobacteria,42N0X@68525|delta/epsilon subdivisions,2YTQP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_60347_1	1165841.SULAR_00490	4.31e-85	267.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_60347_2	1165841.SULAR_00495	8.5e-50	170.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_215103_1	1168034.FH5T_17020	1.39e-91	280.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,2FMY9@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_52532_1	435591.BDI_3785	2.6e-88	274.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,2FNPT@200643|Bacteroidia,22W5A@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
k59_176284_1	716928.AJQT01000025_gene4005	1.9e-26	107.0	COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,4BG95@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glycosyl hydrolase 108	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_1,PG_binding_3
k59_245976_1	1123401.JHYQ01000038_gene1579	2.02e-05	53.1	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	DUF11,SdrD_B
k59_130131_1	1173027.Mic7113_5049	1.81e-23	106.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_10,TPR_12,TPR_7,TPR_8
k59_106623_1	631362.Thi970DRAFT_03474	1.22e-14	74.3	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_106623_2	765914.ThisiDRAFT_0776	5.46e-68	213.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1WX04@135613|Chromatiales	135613|Chromatiales	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_6331_2	911239.CF149_06714	1.09e-19	89.7	2ETQP@1|root,33M8C@2|Bacteria,1QX2A@1224|Proteobacteria,1T34R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0259
k59_207320_1	498211.CJA_0702	1.5e-118	344.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1FGBD@10|Cellvibrio	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_169079_1	313606.M23134_03333	9.31e-24	106.0	COG3209@1|root,COG3209@2|Bacteria,4NKQ5@976|Bacteroidetes,47SE0@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83425_1	1168034.FH5T_06525	3.75e-175	515.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_106627_1	350688.Clos_2492	1.18e-28	113.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25930@186801|Clostridia,36DVP@31979|Clostridiaceae	186801|Clostridia	EH	Aminotransferase class IV	ilvE2	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_160935_1	55601.VANGNB10_cI1846c	7.17e-35	128.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XTI7@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd1	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_160935_2	2340.JV46_26430	1.53e-08	58.2	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1J4F9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM,TPR_19
k59_137597_1	1168034.FH5T_10135	2.15e-157	471.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_13818_1	1286632.P278_26240	1.17e-86	261.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_13818_2	411154.GFO_3410	5.49e-29	111.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_215121_1	91604.ID47_08260	5.22e-44	146.0	COG3293@1|root,32RFK@2|Bacteria,1RI8T@1224|Proteobacteria,2UXPF@28211|Alphaproteobacteria,47GMW@766|Rickettsiales	766|Rickettsiales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
k59_215121_2	1385420.FRA_34c05850	2.11e-46	155.0	COG1234@1|root,COG1234@2|Bacteria,1MZ04@1224|Proteobacteria,1SF4J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_4
k59_245987_1	1168034.FH5T_14055	2.04e-31	117.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,2FT5G@200643|Bacteroidia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_83434_2	1384054.N790_00920	1.71e-37	139.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1X3VI@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_83437_1	408672.NBCG_03735	2.02e-29	122.0	COG0642@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,2GKQX@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_91213_1	1454004.AW11_01265	9.58e-113	340.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2VPFR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_83439_1	1163409.UUA_11613	4.63e-50	170.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,1RRNV@1236|Gammaproteobacteria,1X6MJ@135614|Xanthomonadales	135614|Xanthomonadales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k59_99202_1	1120983.KB894570_gene1400	2.29e-07	57.0	COG2730@1|root,COG2730@2|Bacteria,1QU12@1224|Proteobacteria	1224|Proteobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,Calx-beta,Cellulase
k59_106633_1	1132855.KB913035_gene1252	7.78e-11	61.6	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,2KKDJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_106633_2	743720.Psefu_2247	9.02e-114	330.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1YWG3@136845|Pseudomonas putida group	1236|Gammaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_160938_1	1123073.KB899242_gene1177	1.26e-85	272.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1X2Y0@135614|Xanthomonadales	135614|Xanthomonadales	CP	NADH ubiquinone oxidoreductase subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_184296_2	1298593.TOL_1220	4.54e-38	130.0	2DDZ3@1|root,2ZJWW@2|Bacteria,1P7I9@1224|Proteobacteria,1SUKX@1236|Gammaproteobacteria,1XQB4@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_238390_1	234267.Acid_3820	8.34e-33	130.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,3Y6V8@57723|Acidobacteria	57723|Acidobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16
k59_29557_1	1165841.SULAR_00535	1.5e-08	55.5	COG3384@1|root,COG3384@2|Bacteria,1RB6Z@1224|Proteobacteria,43ACS@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_29557_2	1165841.SULAR_03862	3.35e-40	146.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42YPF@68525|delta/epsilon subdivisions,2YRMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_52873_2	929558.SMGD1_0338	1.48e-29	105.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2YPX8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Cold-shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_153455_1	563040.Saut_1310	6.25e-78	255.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_91558_1	240015.ACP_1882	4.99e-18	86.3	COG0469@1|root,COG0469@2|Bacteria,3Y36V@57723|Acidobacteria,2JHY5@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_91558_2	1379270.AUXF01000002_gene1177	0.000793	43.9	COG2204@1|root,COG2204@2|Bacteria,1ZUNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_146347_1	1168034.FH5T_21240	1.29e-44	148.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,2FSSS@200643|Bacteroidia	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_68538_1	1380387.JADM01000021_gene1656	3.79e-06	51.6	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XIW5@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM,TPR_19
k59_68538_2	765911.Thivi_0919	1.94e-47	159.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1WX2M@135613|Chromatiales	135613|Chromatiales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_200198_1	1165841.SULAR_09779	1.04e-57	179.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2YPES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the thioredoxin family	trx2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_200198_2	1165841.SULAR_09774	1.34e-37	133.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2YN1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_60691_1	1168034.FH5T_11400	1.47e-97	293.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,2FRWR@200643|Bacteroidia	976|Bacteroidetes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_122823_2	1242864.D187_006544	2.06e-26	111.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_215388_1	1168034.FH5T_06120	1.26e-50	177.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_230690_1	323261.Noc_2259	4.28e-08	52.8	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1WY0M@135613|Chromatiales	135613|Chromatiales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_230690_2	1049564.TevJSym_aa01660	1.92e-41	137.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1J6MP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_52896_1	1049564.TevJSym_al00310	1.63e-96	300.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1J5CY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_68545_2	1165841.SULAR_03317	2.69e-08	54.3	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_215395_1	1162668.LFE_0748	1.12e-26	108.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
k59_6667_1	1158612.I580_01575	3.75e-59	204.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,4AZDD@81852|Enterococcaceae	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
k59_161305_1	909663.KI867150_gene610	6.44e-30	122.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MQAI@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_114911_2	1384054.N790_07720	9.07e-70	221.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1X3Y4@135614|Xanthomonadales	135614|Xanthomonadales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_246367_1	1123399.AQVE01000017_gene3690	4.58e-10	59.7	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,46040@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_146376_1	1165841.SULAR_08157	5.4e-32	115.0	COG2259@1|root,COG2259@2|Bacteria,1RKEE@1224|Proteobacteria,42SF5@68525|delta/epsilon subdivisions,2YPGK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_207658_1	1165841.SULAR_06808	4.24e-156	443.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2YMDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_114914_1	472759.Nhal_1446	1.8e-69	211.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1TJD2@1236|Gammaproteobacteria,1WYEP@135613|Chromatiales	135613|Chromatiales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_223333_1	1168034.FH5T_16570	1.11e-129	400.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_207661_1	1165841.SULAR_00950	1.18e-85	269.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_246373_1	313596.RB2501_12537	8.22e-121	362.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_161316_1	1192034.CAP_2901	2.35e-91	278.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YU40@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_153482_1	1117319.PSPO_00822	9.47e-25	100.0	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_153482_2	493475.GARC_2205	1.54e-19	87.4	COG3637@1|root,COG3637@2|Bacteria,1QXK4@1224|Proteobacteria,1T3DI@1236|Gammaproteobacteria,46752@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,SH3_3,SH3_4
k59_148683_1	313596.RB2501_08730	1.55e-133	392.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,1HYWP@117743|Flavobacteriia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase domain protein	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
k59_102290_1	395493.BegalDRAFT_2479	6.89e-75	232.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,461ZM@72273|Thiotrichales	72273|Thiotrichales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_234079_1	378806.STAUR_4159	1.63e-18	90.9	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WNBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K13611	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_218481_1	309801.trd_0408	2.16e-06	50.4	COG2847@1|root,COG2847@2|Bacteria,2G757@200795|Chloroflexi,27Z9Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Pfam:DUF461	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
k59_33031_1	1165841.SULAR_06418	3.29e-47	162.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2YMQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_48294_1	1168034.FH5T_12335	1.17e-96	290.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,2FYAQ@200643|Bacteroidia	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_234082_3	1173762.S4TT67_9CAUD	4.85e-20	92.8	4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses  no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_187436_1	377629.TERTU_4272	4.04e-50	181.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1S15I@1236|Gammaproteobacteria,2PPC6@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_3,PAS_4
k59_17211_1	314607.KB13_289	1.12e-23	93.6	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1KPXQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Acetolactate synthase I III small subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_17211_2	395493.BegalDRAFT_2551	4e-57	192.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1895_2	2340.JV46_24900	4.62e-65	209.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1J5D4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	O-acetylhomoserine sulfhydrylase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	iJN746.PP_2528	Cys_Met_Meta_PP
k59_55962_1	344747.PM8797T_18936	9.76e-21	97.1	COG0457@1|root,COG0457@2|Bacteria,2IY52@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_79300_1	313596.RB2501_03715	1.13e-181	534.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_17212_1	1211115.ALIQ01000189_gene843	6.95e-26	109.0	COG0477@1|root,COG2814@2|Bacteria,1PD60@1224|Proteobacteria,2TSMZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_234095_1	338966.Ppro_3338	1.52e-07	58.2	COG1032@1|root,COG1216@1|root,COG1032@2|Bacteria,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,42U4I@68525|delta/epsilon subdivisions,2WPIS@28221|Deltaproteobacteria,43V77@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_40602_1	765912.Thimo_1868	1.75e-76	254.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_117926_1	550540.Fbal_0307	5.98e-33	129.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1T236@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_226127_1	1480694.DC28_05190	3.97e-24	99.0	2B4IF@1|root,31XAC@2|Bacteria,2JAJT@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_133246_1	1168034.FH5T_18740	4.17e-55	177.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,2FM08@200643|Bacteroidia	976|Bacteroidetes	G	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_218512_1	1165841.SULAR_09379	1.68e-29	109.0	2AIWB@1|root,319DT@2|Bacteria,1Q2F3@1224|Proteobacteria,42VJD@68525|delta/epsilon subdivisions,2YQCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_218512_2	387093.SUN_0408	7.31e-92	278.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42M54@68525|delta/epsilon subdivisions,2YNPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1917_1	305900.GV64_15310	2.05e-93	299.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1XHGK@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
k59_117929_1	765911.Thivi_1041	3.92e-29	110.0	COG0639@1|root,COG0639@2|Bacteria,1RF21@1224|Proteobacteria,1S4CI@1236|Gammaproteobacteria,1WYEH@135613|Chromatiales	135613|Chromatiales	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
k59_117929_2	768671.ThimaDRAFT_1427	7.97e-20	83.2	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1WY24@135613|Chromatiales	135613|Chromatiales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_63711_1	572480.Arnit_1757	6.9e-52	185.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2YN67@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD,Prok-TraM
k59_164269_1	1415754.JQMK01000002_gene2578	8.31e-59	201.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,46485@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	mshE	-	-	ko:K12276	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	T2SSE,T2SSE_N
k59_110124_1	439235.Dalk_3968	5.07e-37	139.0	COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
k59_63713_1	385682.AFSL01000012_gene2849	7.7e-21	94.4	COG3347@1|root,COG3347@2|Bacteria,4NEM0@976|Bacteroidetes,2FWDE@200643|Bacteroidia	976|Bacteroidetes	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
k59_210632_1	637390.AFOH01000117_gene2803	9.3e-29	112.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,2NC8P@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_164635_1	1165841.SULAR_06288	8.66e-48	164.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_164635_2	1165841.SULAR_06283	2.77e-76	241.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_110426_1	686340.Metal_0305	7.01e-07	49.7	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XFC6@135618|Methylococcales	135618|Methylococcales	S	PFAM Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
k59_110426_2	768671.ThimaDRAFT_0286	2.11e-35	126.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1WYEN@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_63979_1	1123034.JMKP01000011_gene539	2.86e-05	51.6	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,1T1FF@1236|Gammaproteobacteria,3NTSR@468|Moraxellaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	irp	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_2239_1	1434929.X946_4838	1.27e-09	64.3	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K13611	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_63980_2	314230.DSM3645_18186	8.82e-162	466.0	COG5433@1|root,COG5433@2|Bacteria,2J2DN@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_56254_1	388413.ALPR1_16773	2.6e-68	221.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,47MFP@768503|Cytophagia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
k59_25321_1	40559.M7TBM7	7.29e-15	79.3	COG1020@1|root,KOG1178@2759|Eukaryota,39PZ6@33154|Opisthokonta,3Q688@4751|Fungi,3RP6Y@4890|Ascomycota	4751|Fungi	I	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,NAD_binding_4,PP-binding
k59_195548_1	1123226.KB899277_gene1245	5.9e-40	150.0	COG1231@1|root,COG1231@2|Bacteria,1TQW0@1239|Firmicutes,4HDHB@91061|Bacilli,26VTY@186822|Paenibacillaceae	91061|Bacilli	E	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
k59_126056_1	1123247.AUIJ01000012_gene822	4.28e-61	198.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TR8F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_25322_1	1179773.BN6_12200	9.28e-31	125.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4DX3H@85010|Pseudonocardiales	201174|Actinobacteria	L	SNF2 family N-terminal domain	helZ	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
k59_172319_1	1187851.A33M_2079	3.28e-57	184.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,3FCTZ@34008|Rhodovulum	28211|Alphaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_17,Fer4_8
k59_172319_2	1384054.N790_04440	1.69e-35	132.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1X4JC@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_2242_1	1121895.Q765_08615	2.67e-20	90.1	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia,2NU08@237|Flavobacterium	976|Bacteroidetes	S	Cytochrome C oxidase assembly protein	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_17510_2	379731.PST_2975	3.04e-48	162.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1Z1FE@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_187818_1	387093.SUN_0555	2.37e-157	457.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_79547_1	215803.DB30_3574	2.56e-32	129.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,43BZA@68525|delta/epsilon subdivisions,2X7A1@28221|Deltaproteobacteria,2YU9I@29|Myxococcales	28221|Deltaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_63988_1	387093.SUN_2044	3.09e-97	305.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_126065_1	1168289.AJKI01000061_gene3377	5.99e-24	107.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,2FQDN@200643|Bacteroidia,3XKDB@558415|Marinilabiliaceae	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
k59_164657_1	1002339.HMPREF9373_1483	6.41e-112	325.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,1SZQV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
k59_63990_1	684949.ATTJ01000001_gene499	7.69e-81	249.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	qmcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k59_126067_1	930169.B5T_02559	6.76e-36	129.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_71607_1	313596.RB2501_10472	1.83e-147	443.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_102577_1	15368.BRADI3G27332.1	4.29e-08	53.5	2CMAK@1|root,2QPT8@2759|Eukaryota,37MKA@33090|Viridiplantae,3GD5I@35493|Streptophyta,3KY9T@4447|Liliopsida,3IAPE@38820|Poales	35493|Streptophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N
k59_195565_1	247639.MGP2080_12023	5.86e-87	271.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1J57E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_102578_1	305700.B447_00165	1.7e-27	111.0	2EBX9@1|root,335WM@2|Bacteria,1NCDM@1224|Proteobacteria,2VYXB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_187839_1	1165841.SULAR_03322	2.26e-56	184.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_187839_2	1165841.SULAR_03327	3.81e-41	143.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_118299_1	1123518.ARWI01000001_gene1312	3.94e-35	127.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,4606Q@72273|Thiotrichales	72273|Thiotrichales	L	Exodeoxyribonuclease III xth	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_234411_1	1165841.SULAR_09054	4.32e-245	682.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_218788_1	1479238.JQMZ01000001_gene2125	3.28e-08	55.5	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,2TTDU@28211|Alphaproteobacteria,43WQ2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
k59_218788_2	596154.Alide2_0238	1.96e-58	190.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2VI1Z@28216|Betaproteobacteria,4AC77@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Di-haem cytochrome c peroxidase	ccp	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_40921_1	1165841.SULAR_01818	3.11e-113	331.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_187848_1	722419.PH505_ae00020	4.06e-12	70.1	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2Q1Y4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K10937	ko02020,ko02030,ko05111,map02020,map02030,map05111	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_234417_1	553171.HMPREF0648_1352	5.34e-21	96.3	COG2826@1|root,COG2826@2|Bacteria,4NFRA@976|Bacteroidetes,2FRII@200643|Bacteroidia	976|Bacteroidetes	L	Integrase core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_38,rve
k59_218794_1	696281.Desru_3126	0.000341	45.8	COG2199@1|root,COG3706@2|Bacteria,1V469@1239|Firmicutes,25BDA@186801|Clostridia,2625Y@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PilJ
k59_245181_1	3988.XP_002535312.1	1.59e-118	357.0	COG0197@1|root,KOG3422@2759|Eukaryota,38965@33090|Viridiplantae,3GY34@35493|Streptophyta,4JV2J@91835|fabids	35493|Streptophyta	J	RIBOSOMAL protein	-	-	-	ko:K02878,ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16,Ribosomal_S3_C
k59_222080_1	930169.B5T_01273	4.88e-111	324.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1S04F@1236|Gammaproteobacteria,1XP23@135619|Oceanospirillales	135619|Oceanospirillales	J	Metallopeptidase family M24	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_206430_1	1165841.SULAR_04402	4.56e-111	322.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2YMGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_206430_2	1220582.RRU01S_12_01390	0.000129	44.7	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,4B9YG@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_113670_1	387093.SUN_2375	3.75e-96	296.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2YRQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_168147_1	387093.SUN_1008	9.73e-193	539.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2YMJB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_136834_1	1165841.SULAR_01160	7.74e-171	484.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,42PT0@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_206434_1	1165841.SULAR_05378	1.6e-140	400.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2YMSS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k59_206434_2	1165841.SULAR_05383	4.09e-62	199.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2YM8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_129318_1	1165841.SULAR_02748	1.15e-97	300.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_129319_1	1116472.MGMO_18c00110	1.42e-18	87.4	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XDWK@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_129319_2	40148.OGLUM01G10730.1	1.13e-09	60.1	COG0142@1|root,KOG0776@2759|Eukaryota,37N02@33090|Viridiplantae,3GDQS@35493|Streptophyta,3KPIN@4447|Liliopsida,3IBQK@38820|Poales	35493|Streptophyta	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_199094_1	1168034.FH5T_04805	4.17e-11	62.4	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_199094_2	1216967.L100_03611	1.52e-08	58.2	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia,34Q84@308865|Elizabethkingia	976|Bacteroidetes	E	Chorismate mutase type II	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
k59_5506_1	1366050.N234_15805	2.75e-120	371.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria,1K2M0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_168156_1	1123277.KB893177_gene3495	1.94e-07	54.7	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_168156_2	385682.AFSL01000053_gene487	6.95e-54	181.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,2FMKB@200643|Bacteroidia,3XITR@558415|Marinilabiliaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_222100_1	1141663.OOC_05727	1.33e-31	123.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,3Z7VE@586|Providencia	1236|Gammaproteobacteria	D	Reduces the stability of FtsZ polymers in the presence of ATP	zapE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
k59_222100_2	1198232.CYCME_0949	7.81e-10	59.3	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,460FM@72273|Thiotrichales	72273|Thiotrichales	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k59_13312_2	935845.JADQ01000027_gene517	9.79e-16	79.3	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,26QT8@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_36905_1	118161.KB235922_gene4072	0.000201	50.1	COG3210@1|root,COG3210@2|Bacteria,1G0EK@1117|Cyanobacteria	1117|Cyanobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
k59_245514_1	314275.MADE_000001022515	9.35e-20	92.0	COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ORF located using Glimmer RBSfinder	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A,DNA_pol_A_exo1
k59_191447_1	358681.BBR47_28930	1.39e-122	400.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_36912_1	1168034.FH5T_07860	1.08e-18	84.7	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,2FP2X@200643|Bacteroidia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_36912_2	1168034.FH5T_07855	2.44e-71	217.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k59_28905_1	555779.Dthio_PD1848	6.9e-150	450.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,430KD@68525|delta/epsilon subdivisions,2WVSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind
k59_129635_1	1165841.SULAR_01385	1.98e-86	259.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2YMW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_206802_1	262768.PAM_250	4.7e-13	68.2	2B9ZZ@1|root,323DM@2|Bacteria,3WUUY@544448|Tenericutes	2|Bacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_206802_2	1232449.BAHV02000026_gene945	1.94e-07	50.8	2DQE0@1|root,33689@2|Bacteria,1VH8J@1239|Firmicutes,24WJ6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152623_1	159087.Daro_0234	1.89e-29	115.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,2KYH4@206389|Rhodocyclales	206389|Rhodocyclales	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
k59_152623_2	765913.ThidrDRAFT_1677	1.62e-45	156.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1WXWI@135613|Chromatiales	135613|Chromatiales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_168471_1	1168034.FH5T_17760	4.78e-169	492.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,4NF2R@976|Bacteroidetes,2FQYA@200643|Bacteroidia	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
k59_129636_1	1121374.KB891575_gene963	1.97e-97	288.0	COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria,1T2JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
k59_28911_1	2340.JV46_04280	7.04e-20	88.6	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,1RQ0R@1236|Gammaproteobacteria,1JAMG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnD	GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896	-	ko:K13014	ko00520,ko01503,map00520,map01503	M00721,M00761	R07662	RC00323,RC01575	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iB21_1397.B21_02141,iBWG_1329.BWG_2029,iEC042_1314.EC042_2499,iECBD_1354.ECBD_1403,iECB_1328.ECB_02182,iECDH10B_1368.ECDH10B_2416,iECDH1ME8569_1439.ECDH1ME8569_2192,iECD_1391.ECD_02182,iECO103_1326.ECO103_2722,iECO111_1330.ECO111_3006,iECO26_1355.ECO26_3246,iECUMN_1333.ECUMN_2597,iECW_1372.ECW_m2447,iEKO11_1354.EKO11_1508,iETEC_1333.ETEC_2390,iEcDH1_1363.EcDH1_1402,iEcHS_1320.EcHS_A2401,iEcolC_1368.EcolC_1393,iJO1366.b2256,iSFV_1184.SFV_2326,iSSON_1240.SSON_2317,iUMNK88_1353.UMNK88_2808,iWFL_1372.ECW_m2447,iY75_1357.Y75_RS11830	Polysacc_deac_1
k59_28911_2	379731.PST_1238	7.98e-12	64.7	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,1Z19H@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_206804_2	1284708.HMPREF1634_03340	6.34e-37	150.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WCF4@538999|Clostridiales incertae sedis	186801|Clostridia	L	Helix-hairpin-helix motif	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_13323_1	237368.SCABRO_00343	1.23e-11	69.7	COG1413@1|root,COG2010@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,2IXPN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_67793_1	189753.AXAS01000075_gene6010	9.27e-86	268.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria,3JVHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_67796_1	445686.E3SL91_9CAUD	6.55e-08	60.5	4QCGC@10239|Viruses,4QZFA@35237|dsDNA viruses  no RNA stage,4QTZH@28883|Caudovirales,4QJ8J@10662|Myoviridae	10662|Myoviridae	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_168477_2	1121875.KB907548_gene1637	2.99e-47	154.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_13328_1	575540.Isop_2441	1.37e-35	127.0	2CEI6@1|root,2ZED5@2|Bacteria,2J3S1@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF669)	-	-	-	-	-	-	-	-	-	-	-	-	DUF669
k59_90688_1	1165841.SULAR_06118	1.05e-124	367.0	COG4775@1|root,COG4775@2|Bacteria,1R536@1224|Proteobacteria	1224|Proteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_121982_1	450851.PHZ_c0453	3.96e-18	87.4	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,2KFM8@204458|Caulobacterales	204458|Caulobacterales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_121982_2	324925.Ppha_1279	6.98e-45	152.0	COG1136@1|root,COG1136@2|Bacteria,1FENX@1090|Chlorobi	1090|Chlorobi	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_229899_1	760192.Halhy_5289	2.78e-24	104.0	COG3552@1|root,COG3552@2|Bacteria,4NK40@976|Bacteroidetes,1IWRV@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_67800_1	1129794.C427_4640	1.08e-66	214.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1SZHG@1236|Gammaproteobacteria,46CVU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_44387_2	1232410.KI421416_gene2592	6.82e-06	50.1	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_67801_1	1381123.AYOD01000052_gene120	5.41e-18	84.3	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2TT0E@28211|Alphaproteobacteria,43HE0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_129639_2	2340.JV46_03620	3.26e-62	205.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1J4Z9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_168488_1	314315.LCA_1604	1.63e-17	88.2	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae	91061|Bacilli	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_36930_1	1267535.KB906767_gene3442	4.69e-29	119.0	COG2801@1|root,COG2801@2|Bacteria,3Y50C@57723|Acidobacteria,2JN2X@204432|Acidobacteriia	204432|Acidobacteriia	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k59_229905_1	1101190.ARWB01000001_gene3394	1.2e-64	217.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,36XN5@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Domain of unknown function (DUF3333)	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_199368_1	754477.Q7C_858	7.68e-93	286.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,45ZZ3@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_121988_1	857087.Metme_2049	8.19e-12	66.6	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1R5T1@1224|Proteobacteria,1S1D6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_8
k59_168494_1	247634.GPB2148_940	2.78e-52	186.0	COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSI4@1236|Gammaproteobacteria,1JBTY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
k59_28927_2	1432055.GLUCORHAEAF1_10140	9.87e-29	115.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSAS@28211|Alphaproteobacteria,2JSXT@204441|Rhodospirillales	204441|Rhodospirillales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k59_5788_1	247634.GPB2148_3317	1.36e-52	186.0	COG2198@1|root,COG2198@2|Bacteria,1NQDP@1224|Proteobacteria,1RXD0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_222442_1	1340493.JNIF01000003_gene4513	5.61e-68	216.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_129645_2	870187.Thini_4318	2.39e-54	192.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZNC@72273|Thiotrichales	1236|Gammaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_160422_1	2340.JV46_16150	4.19e-116	336.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1J4Y5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_121994_1	696369.KI912183_gene1818	8.58e-12	70.5	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,260IB@186807|Peptococcaceae	186801|Clostridia	O	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_82910_2	626418.bglu_1g18970	8.92e-13	71.6	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VJJ7@28216|Betaproteobacteria,1K2F0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_206828_1	265072.Mfla_0083	9.37e-05	48.9	2DNAT@1|root,32WH7@2|Bacteria,1N2AT@1224|Proteobacteria,2VV51@28216|Betaproteobacteria,2KMZ2@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_245541_1	1168034.FH5T_17005	2.25e-75	235.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,2FP1T@200643|Bacteroidia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
k59_245541_2	1168034.FH5T_17010	6.53e-34	125.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,2FMFQ@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_145484_2	870187.Thini_1609	1.15e-64	209.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_145484_3	1129374.AJE_11354	9.34e-08	53.9	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,469Q9@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG5433 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_145484_4	870187.Thini_3937	1.89e-78	245.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_86189_1	1165841.SULAR_07710	2.36e-146	419.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_163550_1	1165841.SULAR_02953	2.92e-205	582.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_217806_4	1444711.CCJF01000003_gene26	2.22e-48	175.0	COG3566@1|root,COG3566@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2213)	-	-	-	ko:K09960	-	-	-	-	ko00000	-	-	-	DUF2213
k59_171363_1	1397528.Q671_09335	1.74e-34	130.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XI7H@135619|Oceanospirillales	135619|Oceanospirillales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_217808_1	67356.KL575588_gene6951	1.26e-08	60.1	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria	201174|Actinobacteria	K	peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
k59_171368_1	1122201.AUAZ01000014_gene279	2.24e-108	322.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RPA8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_148010_1	1168034.FH5T_08440	1.03e-103	328.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia	976|Bacteroidetes	P	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_101632_1	1056820.KB900663_gene3766	8.46e-09	57.8	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,2PMZI@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	L	DNA Topoisomerase IV	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_101632_2	1026882.MAMP_02587	1.29e-39	139.0	COG2353@1|root,COG2353@2|Bacteria,1MZDI@1224|Proteobacteria,1S9EZ@1236|Gammaproteobacteria,462RX@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_209946_1	1207076.ALAT01000170_gene3809	2.95e-61	202.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RN50@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	release factor H-coupled RctB family protein	rtcB	-	6.5.1.3	ko:K14415,ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	RtcB
k59_225451_1	1452718.JBOY01000021_gene719	2e-52	196.0	COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Psort location Cytoplasmic, score	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	Prim-Pol,Toprim_3,Toprim_4
k59_32269_1	105559.Nwat_2763	2.67e-80	251.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM peptidase	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_62976_1	1041930.Mtc_0310	1.94e-18	89.0	COG1578@1|root,arCOG04410@2157|Archaea,2XWGU@28890|Euryarchaeota,2N97C@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_78468_1	876044.IMCC3088_2206	1.15e-219	609.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_70652_1	765911.Thivi_0537	5.94e-21	91.7	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,1S13M@1236|Gammaproteobacteria,1WWSG@135613|Chromatiales	135613|Chromatiales	S	PFAM Alpha beta hydrolase of	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_194467_1	1165841.SULAR_09864	2.8e-122	358.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_62979_1	998674.ATTE01000001_gene4581	1.84e-80	253.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,45ZTY@72273|Thiotrichales	72273|Thiotrichales	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme	-	-	-	-	-	-	-	-	-	-	-	-	RLAN,RimK
k59_209960_1	1209072.ALBT01000047_gene463	9.85e-40	141.0	2EPTW@1|root,33HED@2|Bacteria,1NK6N@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70653_1	1056820.KB900674_gene2674	1.16e-28	116.0	COG3488@1|root,COG3488@2|Bacteria,1PFIC@1224|Proteobacteria,1SAYQ@1236|Gammaproteobacteria,2PPSX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
k59_70653_2	925775.XVE_3734	2.58e-07	52.4	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1X4CG@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_55276_1	1232437.KL662019_gene628	1.64e-39	141.0	COG3385@1|root,COG3385@2|Bacteria,1NUI6@1224|Proteobacteria,42ZJ8@68525|delta/epsilon subdivisions,2WV27@28221|Deltaproteobacteria,2MND0@213118|Desulfobacterales	28221|Deltaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_163573_1	765913.ThidrDRAFT_3856	2.19e-156	453.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria,1WWDR@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM Nitrogenase cofactor biosynthesis protein NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_186773_1	4572.TRIUR3_00083-P1	2.84e-67	221.0	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,3KWRZ@4447|Liliopsida,3IFBD@38820|Poales	35493|Streptophyta	J	Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_132567_1	349521.HCH_04001	2.29e-34	127.0	COG0834@1|root,COG0834@2|Bacteria,1RBXC@1224|Proteobacteria,1S31V@1236|Gammaproteobacteria,1XPZ1@135619|Oceanospirillales	135619|Oceanospirillales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_132567_2	1120970.AUBZ01000013_gene1872	2.09e-11	64.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,46605@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k59_148044_1	1123399.AQVE01000018_gene3407	5.67e-14	75.9	COG1672@1|root,COG1672@2|Bacteria,1NIID@1224|Proteobacteria	1224|Proteobacteria	E	8-amino-7-oxononanoate synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_194479_1	243233.MCA2737	6.94e-07	48.9	2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SHAU@1236|Gammaproteobacteria,1XFBV@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194479_3	765913.ThidrDRAFT_2212	8.54e-20	87.8	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1WX3F@135613|Chromatiales	135613|Chromatiales	E	Belongs to the peptidase M20A family. ArgE subfamily	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_179044_1	1265313.HRUBRA_00732	0.000682	42.4	COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,1J6EK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	-	-	ko:K13053,ko:K14160	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	RecA,SulA
k59_39885_1	1165841.SULAR_03747	5.28e-131	385.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2YNB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_94040_1	232346.JHQL01000002_gene1013	5.3e-72	227.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1XH60@135619|Oceanospirillales	135619|Oceanospirillales	Q	Fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
k59_202281_1	1165841.SULAR_02268	1.16e-25	108.0	COG2200@1|root,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_16505_1	1254432.SCE1572_44195	6.79e-06	53.1	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WNNQ@28221|Deltaproteobacteria,2YUZI@29|Myxococcales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_217825_1	2340.JV46_14410	3.85e-113	356.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1J4IV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_217825_2	2340.JV46_14400	2.27e-45	158.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1J5TI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
k59_217825_3	1049564.TevJSym_ah00830	5.47e-11	62.4	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1J4U2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_117236_1	768671.ThimaDRAFT_2797	3.97e-60	199.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1WWDW@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_47586_1	1395571.TMS3_0103485	1.85e-38	143.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_16506_1	1165841.SULAR_07800	7.26e-60	195.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,42VG8@68525|delta/epsilon subdivisions,2YR2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
k59_16506_2	1165841.SULAR_07795	8.62e-13	67.4	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_39897_1	314265.R2601_20154	2.57e-67	223.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_24258_1	1235813.JCM10003_1047	1.17e-131	384.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia,4AKYN@815|Bacteroidaceae	976|Bacteroidetes	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_217828_1	1122137.AQXF01000004_gene1751	1.35e-22	95.5	COG2062@1|root,COG2062@2|Bacteria,1QVVF@1224|Proteobacteria,2TX4V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k59_217828_2	1122135.KB893134_gene3391	1.28e-10	59.7	COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alkylhydroperoxidase AhpD family core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_202284_1	1127696.HMPREF9134_01745	3.85e-61	200.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,2FN0B@200643|Bacteroidia,22VXJ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_210421_1	1168034.FH5T_01030	1.93e-152	437.0	COG4806@1|root,COG4806@2|Bacteria,4NHKW@976|Bacteroidetes,2FNVS@200643|Bacteroidia	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	rhaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
k59_48068_1	1408473.JHXO01000009_gene3404	4.46e-38	145.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
k59_179584_1	2340.JV46_05260	1.94e-58	192.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,1J515@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Flavocytochrome c sulphide dehydrogenase, flavin-binding	fccB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_179584_2	383407.XOC_4041	1.6e-29	110.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,1RNQE@1236|Gammaproteobacteria,1X54N@135614|Xanthomonadales	135614|Xanthomonadales	C	NADH dehydrogenase NAD(P)H nitroreductase	-	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_86715_1	554065.XP_005849481.1	4.11e-09	63.2	COG5641@1|root,KOG1601@2759|Eukaryota,388QB@33090|Viridiplantae,34HNR@3041|Chlorophyta	3041|Chlorophyta	K	cheY-homologous receiver domain	-	-	2.3.2.27	ko:K10143,ko:K16240	ko04115,ko04120,ko04712,map04115,map04120,map04712	-	-	-	ko00000,ko00001,ko01000,ko04121	-	-	-	Response_reg,WD40
k59_94524_1	1165841.SULAR_03842	4.03e-117	338.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42SWD@68525|delta/epsilon subdivisions,2YP1S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_24787_1	1047013.AQSP01000142_gene240	3.71e-53	186.0	COG3533@1|root,COG3533@2|Bacteria,2NNW0@2323|unclassified Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
k59_164054_1	1279015.KB908461_gene1763	4.28e-63	207.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1Y3NJ@135624|Aeromonadales	135624|Aeromonadales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_164054_2	2340.JV46_13250	1.5e-07	50.4	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1J6Y3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2927 DNA polymerase III, chi subunit	holC	GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
k59_164055_1	1008459.TASI_1312	2.15e-06	48.1	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,3T1RK@506|Alcaligenaceae	28216|Betaproteobacteria	S	ABC transporter, ATP-binding protein	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k59_164055_2	2340.JV46_09230	5.83e-108	317.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1J5I0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_9504_1	1131553.JIBI01000005_gene2192	1.16e-29	118.0	COG0589@1|root,COG0589@2|Bacteria,1PE08@1224|Proteobacteria,2VNHV@28216|Betaproteobacteria,373RK@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_125451_1	1046714.AMRX01000006_gene3008	4.66e-90	296.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_210438_1	1279019.ARQK01000061_gene1848	6.89e-58	191.0	COG2159@1|root,COG2159@2|Bacteria,1R44U@1224|Proteobacteria,1SZYU@1236|Gammaproteobacteria,1X1U1@135613|Chromatiales	135613|Chromatiales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
k59_40425_1	1165841.SULAR_10564	1.69e-69	221.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2YMBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_19530_1	1132855.KB913035_gene1918	2.26e-17	81.6	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,2KMC2@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_19530_2	292415.Tbd_2059	9.32e-43	153.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2VJUV@28216|Betaproteobacteria	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k59_58404_1	1123277.KB893184_gene3990	1.57e-31	120.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,47R92@768503|Cytophagia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_244136_1	869213.JCM21142_83260	1.46e-15	80.1	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_120499_2	1122226.AUHX01000013_gene1285	2.05e-17	80.1	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_190049_1	582744.Msip34_2622	2.38e-13	70.1	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,2VV7N@28216|Betaproteobacteria,2KMP7@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
k59_244139_1	156578.ATW7_03127	1.54e-26	114.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_19536_1	1123277.KB893243_gene184	1.21e-21	99.0	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,47JHQ@768503|Cytophagia	976|Bacteroidetes	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_12,TPR_7,TPR_8
k59_120500_2	2340.JV46_28910	1.23e-55	175.0	COG0607@1|root,COG0607@2|Bacteria,1QMXA@1224|Proteobacteria,1S6DI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Pfam Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_143768_1	203275.BFO_0193	5.11e-15	73.6	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia,22WAK@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_143768_2	1122973.KB904205_gene1819	4.69e-32	120.0	COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,22WZN@171551|Porphyromonadaceae	976|Bacteroidetes	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_135837_1	1408423.JHYA01000002_gene861	8.15e-16	79.0	COG0688@1|root,COG0688@2|Bacteria	2|Bacteria	I	phosphatidylethanolamine metabolic process	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_167062_1	1165841.SULAR_02748	9.59e-73	233.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_221013_1	1168034.FH5T_05235	1.78e-129	385.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,2G0E2@200643|Bacteroidia	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_128329_1	95619.PM1_0202940	3.08e-23	89.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center	rubA	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
k59_128329_2	349521.HCH_05938	3.01e-44	155.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1XI4K@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_19549_1	1279009.ADICEAN_01017	1.82e-65	223.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_221016_1	1144275.COCOR_02593	4.53e-94	316.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K16416	ko01052,map01052	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_112706_1	1038922.PflQ2_0416	3.09e-26	117.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1YNX1@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Histidine kinase	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_112713_1	1396418.BATQ01000129_gene4842	4.84e-48	165.0	COG2805@1|root,COG2805@2|Bacteria,46SY2@74201|Verrucomicrobia,2ITP5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_120507_1	468059.AUHA01000002_gene928	7.37e-96	301.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1IPE8@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
k59_112714_1	765910.MARPU_15335	8.52e-31	130.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WW9N@135613|Chromatiales	135613|Chromatiales	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_2,sCache_2
k59_27539_1	998674.ATTE01000001_gene589	4.91e-66	221.0	COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	50S ribosome-binding GTPase	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
k59_228631_2	702450.CUW_1434	2.07e-22	100.0	COG4467@1|root,COG4467@2|Bacteria,1VK8R@1239|Firmicutes,3VTNX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_221035_1	666685.R2APBS1_3956	3.4e-29	115.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1X3BM@135614|Xanthomonadales	135614|Xanthomonadales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_221035_2	1255043.TVNIR_3023	5.66e-48	161.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1WX89@135613|Chromatiales	135613|Chromatiales	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_120527_1	1168034.FH5T_21810	8.95e-67	213.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_120527_2	927658.AJUM01000034_gene149	5.76e-19	85.1	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,2FMQM@200643|Bacteroidia,3XIMK@558415|Marinilabiliaceae	976|Bacteroidetes	C	FMN_bind	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
k59_143781_1	1168034.FH5T_02500	1.34e-46	162.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_182456_1	1165841.SULAR_06303	1.48e-86	270.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_135862_1	379066.GAU_0984	1.13e-20	87.4	COG3682@1|root,COG3682@2|Bacteria,1ZV5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_135862_2	509190.Cseg_3535	4.6e-11	71.2	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_M56,Secretin,TonB_C
k59_97216_1	1395571.TMS3_0123475	1.12e-22	90.9	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_97216_2	765912.Thimo_1080	3.07e-18	82.4	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_120538_1	1038869.AXAN01000074_gene4065	1.25e-16	87.8	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,1K5MF@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
k59_135868_1	28072.Nos7524_1936	7.88e-28	116.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HJGC@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_120539_1	489825.LYNGBM3L_26240	7.72e-38	145.0	COG0515@1|root,COG1672@1|root,COG3899@1|root,COG0515@2|Bacteria,COG1672@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase,SpoIIE
k59_4605_1	387093.SUN_0531	1.33e-64	207.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2YNKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_66253_1	266265.Bxe_A3739	6.92e-74	232.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,2VMVE@28216|Betaproteobacteria,1K5SK@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_221057_1	2340.JV46_20160	1.02e-72	239.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J57S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	cation transport ATPase	copA	GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035434,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060003,GO:0061687,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071292,GO:0071944,GO:0090662,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0099131,GO:1902601,GO:1990169	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	iEC55989_1330.EC55989_0497,iECIAI1_1343.ECIAI1_0487,iECO103_1326.ECO103_0460,iECSE_1348.ECSE_0509,iECW_1372.ECW_m0557,iEKO11_1354.EKO11_3363,iWFL_1372.ECW_m0557	E1-E2_ATPase,HMA,Hydrolase
k59_4609_1	1111728.ATYS01000016_gene4619	2.33e-19	84.7	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_0608	CoA_binding,Ligase_CoA
k59_4609_2	3067.XP_002949757.1	9.01e-52	176.0	COG0045@1|root,KOG2799@2759|Eukaryota,37IF6@33090|Viridiplantae,34J5B@3041|Chlorophyta	3041|Chlorophyta	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate- level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	-	-	6.2.1.4,6.2.1.5	ko:K01900	ko00020,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00432,R00727	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iRC1080.CRv4_Au5_s17_g7113_t1	ATP-grasp_2,Ligase_CoA
k59_58418_1	132113.XP_003489930.1	3.68e-07	56.6	COG0515@1|root,KOG0612@2759|Eukaryota,38BFH@33154|Opisthokonta,3BATS@33208|Metazoa,3CXFD@33213|Bilateria,41UXH@6656|Arthropoda,3SJ2Y@50557|Insecta,46DPR@7399|Hymenoptera	33208|Metazoa	T	Rho Binding	ROCK2	GO:0000003,GO:0000022,GO:0000070,GO:0000226,GO:0000278,GO:0000280,GO:0000281,GO:0000819,GO:0000902,GO:0000904,GO:0000910,GO:0000922,GO:0001654,GO:0001700,GO:0001726,GO:0001736,GO:0001737,GO:0001738,GO:0001745,GO:0001775,GO:0001816,GO:0001817,GO:0001819,GO:0001838,GO:0001841,GO:0001843,GO:0001932,GO:0001934,GO:0001952,GO:0001954,GO:0002009,GO:0002064,GO:0002119,GO:0002164,GO:0002165,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003006,GO:0003008,GO:0003012,GO:0003381,GO:0003382,GO:0003383,GO:0003384,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005886,GO:0005911,GO:0005912,GO:0005913,GO:0005938,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006915,GO:0006928,GO:0006936,GO:0006939,GO:0006955,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007059,GO:0007097,GO:0007098,GO:0007143,GO:0007154,GO:0007155,GO:0007159,GO:0007163,GO:0007164,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007186,GO:0007249,GO:0007264,GO:0007265,GO:0007266,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007300,GO:0007302,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007391,GO:0007399,GO:0007423,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008277,GO:0008335,GO:0008360,GO:0008544,GO:0008625,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009886,GO:0009887,GO:0009888,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009913,GO:0009966,GO:0009967,GO:0009987,GO:0009994,GO:0010033,GO:0010171,GO:0010172,GO:0010243,GO:0010468,GO:0010494,GO:0010506,GO:0010508,GO:0010562,GO:0010563,GO:0010564,GO:0010594,GO:0010595,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010632,GO:0010634,GO:0010638,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010810,GO:0010811,GO:0010824,GO:0010825,GO:0010830,GO:0010921,GO:0010923,GO:0010941,GO:0010950,GO:0010952,GO:0010975,GO:0012501,GO:0012505,GO:0014020,GO:0014070,GO:0014742,GO:0014743,GO:0014812,GO:0015630,GO:0016020,GO:0016032,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016331,GO:0016358,GO:0016477,GO:0016525,GO:0016740,GO:0016772,GO:0016773,GO:0017016,GO:0017048,GO:0017049,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019058,GO:0019079,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019953,GO:0021700,GO:0021915,GO:0022008,GO:0022402,GO:0022406,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0022612,GO:0022614,GO:0023051,GO:0023052,GO:0023056,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030048,GO:0030054,GO:0030100,GO:0030111,GO:0030141,GO:0030154,GO:0030155,GO:0030162,GO:0030182,GO:0030261,GO:0030334,GO:0030335,GO:0030855,GO:0030856,GO:0030865,GO:0030866,GO:0031023,GO:0031032,GO:0031175,GO:0031252,GO:0031267,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031330,GO:0031331,GO:0031344,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031532,GO:0031616,GO:0031974,GO:0031982,GO:0031983,GO:0032060,GO:0032065,GO:0032091,GO:0032231,GO:0032233,GO:0032268,GO:0032269,GO:0032270,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032515,GO:0032643,GO:0032723,GO:0032870,GO:0032878,GO:0032879,GO:0032880,GO:0032886,GO:0032940,GO:0032954,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033206,GO:0033574,GO:0033993,GO:0034103,GO:0034105,GO:0034248,GO:0034249,GO:0034250,GO:0034613,GO:0034774,GO:0035107,GO:0035114,GO:0035120,GO:0035148,GO:0035190,GO:0035191,GO:0035220,GO:0035239,GO:0035295,GO:0035303,GO:0035304,GO:0035305,GO:0035308,GO:0035315,GO:0035316,GO:0035317,GO:0035507,GO:0035509,GO:0035556,GO:0035770,GO:0036211,GO:0036230,GO:0036464,GO:0039694,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0040038,GO:0042067,GO:0042119,GO:0042176,GO:0042177,GO:0042221,GO:0042325,GO:0042327,GO:0042752,GO:0042981,GO:0042995,GO:0043009,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043299,GO:0043312,GO:0043393,GO:0043408,GO:0043410,GO:0043412,GO:0043434,GO:0043502,GO:0043523,GO:0043524,GO:0043666,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044291,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044703,GO:0045055,GO:0045123,GO:0045177,GO:0045179,GO:0045184,GO:0045185,GO:0045321,GO:0045595,GO:0045597,GO:0045601,GO:0045604,GO:0045616,GO:0045664,GO:0045682,GO:0045765,GO:0045785,GO:0045787,GO:0045861,GO:0045862,GO:0045936,GO:0045937,GO:0046605,GO:0046607,GO:0046903,GO:0046907,GO:0048010,GO:0048013,GO:0048285,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048565,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048592,GO:0048598,GO:0048599,GO:0048609,GO:0048638,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050767,GO:0050770,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0050900,GO:0050901,GO:0051020,GO:0051043,GO:0051045,GO:0051049,GO:0051093,GO:0051094,GO:0051098,GO:0051100,GO:0051128,GO:0051129,GO:0051130,GO:0051147,GO:0051153,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051231,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051272,GO:0051276,GO:0051298,GO:0051301,GO:0051302,GO:0051321,GO:0051336,GO:0051345,GO:0051346,GO:0051451,GO:0051492,GO:0051493,GO:0051495,GO:0051496,GO:0051640,GO:0051641,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0051726,GO:0051893,GO:0051894,GO:0051960,GO:0052547,GO:0052548,GO:0055123,GO:0060142,GO:0060205,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060465,GO:0060548,GO:0060562,GO:0060606,GO:0060627,GO:0061041,GO:0061640,GO:0061756,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070161,GO:0070167,GO:0070168,GO:0070252,GO:0070507,GO:0070727,GO:0070848,GO:0070887,GO:0071103,GO:0071310,GO:0071363,GO:0071394,GO:0071396,GO:0071407,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071840,GO:0071944,GO:0072175,GO:0072518,GO:0072657,GO:0072659,GO:0080090,GO:0080134,GO:0090068,GO:0090109,GO:0090175,GO:0090257,GO:0090270,GO:0090271,GO:0090303,GO:0090596,GO:0097190,GO:0097191,GO:0097708,GO:0098609,GO:0098693,GO:0098813,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099568,GO:0099738,GO:0106036,GO:0106037,GO:0110020,GO:0110053,GO:0110061,GO:0120025,GO:0120031,GO:0120035,GO:0120036,GO:0120039,GO:0140013,GO:0140014,GO:0140058,GO:0140096,GO:0150031,GO:0150033,GO:1900180,GO:1900182,GO:1900221,GO:1900223,GO:1900242,GO:1901214,GO:1901215,GO:1901342,GO:1901343,GO:1901550,GO:1901564,GO:1901648,GO:1901652,GO:1901654,GO:1901655,GO:1901698,GO:1901700,GO:1901701,GO:1901739,GO:1901888,GO:1901889,GO:1901890,GO:1902003,GO:1902004,GO:1902430,GO:1902531,GO:1902533,GO:1902850,GO:1902903,GO:1902905,GO:1902959,GO:1902961,GO:1902965,GO:1902966,GO:1902991,GO:1902992,GO:1902993,GO:1903034,GO:1903035,GO:1903036,GO:1903046,GO:1903047,GO:1903140,GO:1903347,GO:1903391,GO:1903393,GO:1903421,GO:1903429,GO:1903431,GO:1903827,GO:1903828,GO:1903829,GO:1905203,GO:1905205,GO:1905245,GO:1905247,GO:1905330,GO:1905666,GO:1905668,GO:1905905,GO:1990776,GO:1990778,GO:1990904,GO:2000026,GO:2000027,GO:2000040,GO:2000050,GO:2000095,GO:2000114,GO:2000145,GO:2000147,GO:2000181,GO:2000810	2.7.11.1	ko:K04514,ko:K16307,ko:K17388	ko04022,ko04024,ko04062,ko04071,ko04270,ko04310,ko04350,ko04360,ko04510,ko04530,ko04611,ko04670,ko04810,ko04921,ko05130,ko05131,ko05132,ko05200,ko05205,ko05206,map04022,map04024,map04062,map04071,map04270,map04310,map04350,map04360,map04510,map04530,map04611,map04670,map04810,map04921,map05130,map05131,map05132,map05200,map05205,map05206	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03036	-	-	-	Pkinase,Rho_Binding
k59_28003_1	1165841.SULAR_09994	7.56e-157	450.0	COG0446@1|root,COG0446@2|Bacteria,1PWV7@1224|Proteobacteria,42QCM@68525|delta/epsilon subdivisions,2YND4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1252 NADH dehydrogenase FAD-containing subunit	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_121018_2	631362.Thi970DRAFT_03281	1.77e-11	67.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WX3E@135613|Chromatiales	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_144269_1	1312959.KI914674_gene3398	2.55e-20	96.7	COG3087@1|root,COG3291@1|root,COG3087@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Laminin_G_3,PKD
k59_136261_1	385682.AFSL01000019_gene2277	7.64e-32	125.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,2FRN0@200643|Bacteroidia,3XIRF@558415|Marinilabiliaceae	976|Bacteroidetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_58828_1	1165841.SULAR_00680	1.03e-74	246.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_28004_1	502025.Hoch_0168	1.63e-13	82.4	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
k59_151642_1	99598.Cal7507_0154	4.12e-39	140.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1HKMD@1161|Nostocales	1117|Cyanobacteria	O	TIGRFAM hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_151642_2	1049564.TevJSym_aa02470	3.77e-66	209.0	COG2215@1|root,COG2215@2|Bacteria,1R3QK@1224|Proteobacteria,1SARN@1236|Gammaproteobacteria,1JB4F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2,NicO
k59_43487_1	349521.HCH_02231	4.82e-113	340.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1XJC4@135619|Oceanospirillales	135619|Oceanospirillales	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_19962_1	697282.Mettu_2580	4.45e-110	334.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XEQK@135618|Methylococcales	135618|Methylococcales	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_229009_1	143224.JQMD01000002_gene3749	5.99e-36	135.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_229009_2	143224.JQMD01000002_gene3750	1.16e-35	124.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
k59_182795_1	1168034.FH5T_01195	3.74e-58	186.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,2FSSX@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_28008_1	1165841.SULAR_08512	1.36e-44	148.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928	GTP_cyclohydroI
k59_244593_1	1121405.dsmv_3781	6.12e-128	374.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_236999_1	1120953.AUBH01000008_gene322	5.3e-26	106.0	2EWRZ@1|root,33Q3P@2|Bacteria,1RM3I@1224|Proteobacteria,1S7Q8@1236|Gammaproteobacteria,46AG1@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k59_51074_1	395494.Galf_2325	3.43e-46	158.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,44WHN@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_97695_1	387092.NIS_1638	6.96e-34	125.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YM7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_4971_1	886377.Murru_0456	5.24e-22	92.4	28HPY@1|root,2Z7XS@2|Bacteria,4NJIW@976|Bacteroidetes,1HZBP@117743|Flavobacteriia	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
k59_4971_2	313603.FB2170_00410	2.29e-52	168.0	COG5502@1|root,COG5502@2|Bacteria,4NN8N@976|Bacteroidetes,1I1CJ@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
k59_167500_1	313596.RB2501_00906	1.93e-55	195.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_198408_1	396588.Tgr7_2172	9.7e-24	93.6	COG2932@1|root,COG2932@2|Bacteria,1NBZE@1224|Proteobacteria	1224|Proteobacteria	K	PFAM Peptidase S24 S26A S26B, conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
k59_198408_2	1046714.AMRX01000007_gene2014	5.96e-78	245.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,464H7@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN746.PP_0436	S4,tRNA-synt_1b
k59_144294_1	926560.KE387023_gene2304	5.36e-14	68.6	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
k59_96130_1	1245471.PCA10_20470	3.16e-53	182.0	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,1YCWG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_88322_1	1168065.DOK_13579	3.11e-51	177.0	COG1960@1|root,COG1960@2|Bacteria,1P7WH@1224|Proteobacteria,1RNZQ@1236|Gammaproteobacteria,1J8H3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
k59_11120_2	1122604.JONR01000010_gene3937	3.97e-35	128.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1X61Y@135614|Xanthomonadales	135614|Xanthomonadales	NU	pilus assembly protein pilp	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_227541_2	1165841.SULAR_03632	1.51e-42	147.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_165904_2	517418.Ctha_1186	8.73e-53	178.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
k59_165904_3	237368.SCABRO_01396	7.77e-53	175.0	COG3766@1|root,COG3766@2|Bacteria	2|Bacteria	E	membrane	-	-	-	ko:K08989	-	-	-	-	ko00000	-	-	-	DUF350
k59_103717_1	1123261.AXDW01000004_gene2714	1.1e-45	155.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1XCJT@135614|Xanthomonadales	135614|Xanthomonadales	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_103717_2	1122197.ATWI01000009_gene1442	7.85e-13	68.2	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,464JP@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	yejF	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K13896	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k59_235494_1	1168034.FH5T_11160	1.13e-25	98.6	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,2FPT5@200643|Bacteroidia	976|Bacteroidetes	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
k59_235494_2	1168034.FH5T_11165	3.48e-64	209.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,2FM6E@200643|Bacteroidia	976|Bacteroidetes	G	Phosphoglucosamine mutase	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_26460_1	397945.Aave_0573	2.5e-06	48.9	COG0665@1|root,COG0665@2|Bacteria,1MVG3@1224|Proteobacteria,2VMID@28216|Betaproteobacteria,4AFSS@80864|Comamonadaceae	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_26460_2	509190.Cseg_2581	2.88e-34	134.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2U0ZY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_158019_1	1165841.SULAR_00600	3.21e-42	144.0	28NXH@1|root,2ZBV3@2|Bacteria,1RDDP@1224|Proteobacteria,42ZNQ@68525|delta/epsilon subdivisions,2YRRT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49610_1	243233.MCA2008	1.4e-22	97.1	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1XF3W@135618|Methylococcales	135618|Methylococcales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
k59_227545_1	243090.RB13148	2.23e-15	76.3	COG3119@1|root,COG3119@2|Bacteria,2J1TA@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_227545_2	1168034.FH5T_05790	6.77e-41	143.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,2FPCB@200643|Bacteroidia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_196888_1	1395513.P343_01850	1.65e-17	87.8	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26NJC@186821|Sporolactobacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_127178_1	697282.Mettu_3328	1.77e-110	330.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,1RSFD@1236|Gammaproteobacteria,1XEEZ@135618|Methylococcales	135618|Methylococcales	C	protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_119481_1	291985.CCSI01000007_gene482	2.15e-09	65.9	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,1QU09@1224|Proteobacteria,2TXRZ@28211|Alphaproteobacteria,2KEJA@204457|Sphingomonadales	204457|Sphingomonadales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188963_1	211586.SO_0725	8.17e-87	277.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,2QAHK@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_204405_1	1165841.SULAR_03218	4.57e-107	318.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_150210_2	1165841.SULAR_09109	9.5e-57	184.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_11132_1	1122139.KB907887_gene151	2.28e-49	172.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1XHAR@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k59_127188_1	1165841.SULAR_09924	2.5e-117	342.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2YM8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_235505_1	398767.Glov_2787	1.53e-09	66.6	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
k59_41951_1	1123279.ATUS01000003_gene581	3.03e-68	233.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J4MB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_18515_2	1433126.BN938_2413	1.01e-19	82.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,2FTD1@200643|Bacteroidia,22VHJ@171550|Rikenellaceae	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_119491_1	395493.BegalDRAFT_3501	1.42e-30	125.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9
k59_80708_1	765911.Thivi_0537	5.4e-102	311.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,1S13M@1236|Gammaproteobacteria,1WWSG@135613|Chromatiales	135613|Chromatiales	S	PFAM Alpha beta hydrolase of	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_72822_1	768671.ThimaDRAFT_4552	3.29e-87	273.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_72822_2	396595.TK90_0066	3.1e-61	190.0	2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria,1S4CA@1236|Gammaproteobacteria,1WY9U@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_72822_3	713587.THITH_01425	4.91e-53	171.0	COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,1S2MS@1236|Gammaproteobacteria,1WY6J@135613|Chromatiales	135613|Chromatiales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
k59_41956_1	1165841.SULAR_04217	2.5e-76	238.0	COG0477@1|root,COG2814@2|Bacteria,1R7DW@1224|Proteobacteria,43BJI@68525|delta/epsilon subdivisions,2YT98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_235512_1	991905.SL003B_2157	3.93e-20	87.8	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,4BR8B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	natD	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_235512_2	1297863.APJF01000001_gene2147	2.81e-68	218.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2TU0F@28211|Alphaproteobacteria,3JQNI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_96138_1	313596.RB2501_14609	7.33e-31	119.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
k59_96138_2	313603.FB2170_12016	2.31e-33	118.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1I1YP@117743|Flavobacteriia,2PHE4@252356|Maribacter	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_127190_1	1121459.AQXE01000013_gene2240	3.13e-06	50.1	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2M85X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_127190_2	99598.Cal7507_1681	0.000304	43.5	COG0206@1|root,COG0206@2|Bacteria,1G0AN@1117|Cyanobacteria,1HIWE@1161|Nostocales	1117|Cyanobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000910,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0032153,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_26486_2	1172190.M947_00845	1.22e-41	150.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_111668_1	1296415.JACC01000011_gene532	3.29e-17	87.0	COG0419@1|root,COG2304@1|root,COG0419@2|Bacteria,COG2304@2|Bacteria,4PN9E@976|Bacteroidetes	976|Bacteroidetes	L	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188976_1	1235788.C802_00355	2.03e-05	52.8	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMCC@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_11148_1	29581.BW37_01825	1.18e-14	72.0	COG0454@1|root,COG0456@2|Bacteria,1N79D@1224|Proteobacteria,2VXGY@28216|Betaproteobacteria,47504@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_227559_1	1168034.FH5T_16625	2.33e-65	209.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,2FNS0@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_227559_2	314230.DSM3645_05315	6.69e-06	48.5	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_127194_1	1408473.JHXO01000001_gene2237	3.39e-89	286.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,2FMSF@200643|Bacteroidia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_134780_1	395493.BegalDRAFT_0387	1.39e-20	97.1	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,1MX2X@1224|Proteobacteria,1RY8H@1236|Gammaproteobacteria,4625Z@72273|Thiotrichales	72273|Thiotrichales	Q	methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25
k59_11149_1	648757.Rvan_0984	1.03e-82	271.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2TR2N@28211|Alphaproteobacteria,3N80D@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_96158_1	1121935.AQXX01000112_gene5751	2.7e-34	127.0	COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphoesterase DHHA1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
k59_41980_1	1165841.SULAR_00545	1.52e-55	180.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_111681_1	2340.JV46_13300	3.63e-178	531.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J582@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_41981_1	765912.Thimo_3517	1.11e-93	290.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1WXDW@135613|Chromatiales	135613|Chromatiales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_196923_1	1121875.KB907550_gene727	3.71e-58	182.0	2DDNY@1|root,2ZIRM@2|Bacteria,4P8P6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57386_1	591157.SSLG_06039	1.44e-18	92.8	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	6.3.2.14	ko:K02364	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_103753_1	1123053.AUDG01000079_gene1028	8.98e-76	249.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1P31Y@1224|Proteobacteria,1RQNS@1236|Gammaproteobacteria,1WZWH@135613|Chromatiales	135613|Chromatiales	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_204429_4	316274.Haur_1938	2.18e-42	158.0	COG3385@1|root,COG3385@2|Bacteria,2G7KG@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_18532_1	1121403.AUCV01000124_gene2974	1.21e-162	474.0	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2MMJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_18533_1	1165841.SULAR_07705	9.53e-92	284.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_111686_1	546268.NEISUBOT_04742	3.82e-06	53.9	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KPXZ@206351|Neisseriales	206351|Neisseriales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_212214_1	2340.JV46_17200	1.08e-53	174.0	COG5342@1|root,COG5342@2|Bacteria,1Q3S9@1224|Proteobacteria,1RTRH@1236|Gammaproteobacteria,1JBBR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Invasion associated locus B (IalB) protein	-	-	-	-	-	-	-	-	-	-	-	-	IalB
k59_181395_1	1123263.AUKY01000062_gene2312	1.07e-05	46.6	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,3VPCF@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
k59_173508_1	1121405.dsmv_3558	3.95e-70	221.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2MIBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k59_34474_1	1165841.SULAR_00475	1.95e-124	364.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2YMMP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_212806_1	3702.ATCG00180.1	9.36e-101	310.0	COG0086@1|root,2QPYA@2759|Eukaryota,37HVM@33090|Viridiplantae,3GFWY@35493|Streptophyta	35493|Streptophyta	K	DNA-directed RNA polymerase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009295,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3
k59_212806_2	4155.Migut.D01417.1.p	1.48e-93	296.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,44N3V@71274|asterids	35493|Streptophyta	K	RNA polymerase Rpb2, domain 7	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_189599_1	251229.Chro_3726	2.97e-30	124.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,3VJE8@52604|Pleurocapsales	1117|Cyanobacteria	Q	COGs COG1020 Non-ribosomal peptide synthetase modules and related protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
k59_220654_1	4081.Solyc01g007360.2.1	1.59e-44	148.0	2CNI2@1|root,2QWGG@2759|Eukaryota,37P4I@33090|Viridiplantae,3GGGH@35493|Streptophyta,44MN2@71274|asterids	35493|Streptophyta	S	Ycf4	ycf4	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016043,GO:0019684,GO:0022607,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048564,GO:0051082,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Ycf4
k59_158626_1	1165841.SULAR_06438	1.07e-120	355.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2YMCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_166554_1	338963.Pcar_2426	3.81e-113	356.0	COG5114@1|root,COG5114@2|Bacteria,1QV7J@1224|Proteobacteria	1224|Proteobacteria	B	positive regulation of histone acetylation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27111_1	537970.HCAN_0859	1.02e-43	146.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2YPGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_182006_2	329381.D9ICQ4_9CAUD	1.42e-17	84.3	4QHQV@10239|Viruses,4QX6C@35237|dsDNA viruses  no RNA stage,4QRJ7@28883|Caudovirales,4QIJU@10662|Myoviridae	10662|Myoviridae	S	virus tail assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182007_1	395493.BegalDRAFT_0217	5.34e-115	348.0	COG0747@1|root,COG0747@2|Bacteria,1NQM8@1224|Proteobacteria	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_228169_1	1168034.FH5T_13835	1.23e-35	128.0	2B0HH@1|root,31SV0@2|Bacteria,4NRU4@976|Bacteroidetes,2FTFR@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_235462_2	1499967.BAYZ01000013_gene6445	3.36e-09	58.9	COG1748@1|root,COG1748@2|Bacteria,2NNZ1@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lys2	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
k59_181324_2	1123053.AUDG01000018_gene3021	3.67e-06	50.4	COG2128@1|root,COG2128@2|Bacteria,1N1YR@1224|Proteobacteria,1SBPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41896_1	1165841.SULAR_04222	1.55e-130	372.0	COG0546@1|root,COG0546@2|Bacteria,1NDKE@1224|Proteobacteria,42SW4@68525|delta/epsilon subdivisions,2YPI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_41896_2	1165841.SULAR_04217	4.18e-125	366.0	COG0477@1|root,COG2814@2|Bacteria,1R7DW@1224|Proteobacteria,43BJI@68525|delta/epsilon subdivisions,2YT98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_34414_1	998674.ATTE01000001_gene581	4.12e-45	166.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k59_26399_1	2340.JV46_24650	1.73e-28	114.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1J6FD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
k59_196842_1	1165841.SULAR_06258	2.41e-117	352.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2YMNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_119408_1	572480.Arnit_1226	9.79e-63	204.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2YNPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Abc transporter, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_41899_1	1165841.SULAR_00115	1.85e-99	290.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,42RGX@68525|delta/epsilon subdivisions,2YPA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TIGRFAM DJ-1 family protein	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_243043_1	478741.JAFS01000002_gene87	4.36e-79	246.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_41901_1	1279017.AQYJ01000028_gene2477	2.08e-80	261.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1PYUK@1224|Proteobacteria,1S0VV@1236|Gammaproteobacteria,468XB@72275|Alteromonadaceae	1236|Gammaproteobacteria	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
k59_96088_1	1173029.JH980292_gene1337	1.42e-25	110.0	COG0642@1|root,COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_127154_1	391596.PBAL39_24233	1.28e-09	68.2	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1IRID@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_173440_1	118168.MC7420_2811	8.89e-05	50.4	COG2133@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1G3EW@1117|Cyanobacteria,1HBBU@1150|Oscillatoriales	1117|Cyanobacteria	Q	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8,HemolysinCabind,Laminin_G_3,PKD
k59_173442_1	1121930.AQXG01000016_gene1802	1.19e-14	73.2	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IP88@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_49583_1	1232683.ADIMK_3075	1.8e-98	294.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,464R9@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_119419_1	626887.J057_13161	1.34e-54	189.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,465RW@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_11109_1	443144.GM21_0323	1.44e-28	117.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42NRK@68525|delta/epsilon subdivisions,2WIM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
k59_57304_1	8010.XP_010868546.1	9.07e-32	119.0	COG0302@1|root,KOG2698@2759|Eukaryota,38CYY@33154|Opisthokonta,3BE4R@33208|Metazoa,3CYQZ@33213|Bilateria,483PV@7711|Chordata,48YN8@7742|Vertebrata,49S5J@7898|Actinopterygii	33208|Metazoa	H	GTP cyclohydrolase	-	GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005515,GO:0006066,GO:0006082,GO:0006520,GO:0006570,GO:0006582,GO:0006584,GO:0006585,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009108,GO:0009712,GO:0009713,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0018958,GO:0019238,GO:0019438,GO:0019748,GO:0019751,GO:0019752,GO:0034311,GO:0034312,GO:0034641,GO:0042416,GO:0042417,GO:0042423,GO:0042438,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044550,GO:0046146,GO:0046148,GO:0046165,GO:0046173,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0097164,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_235480_1	272134.KB731325_gene528	9.45e-32	128.0	COG0515@1|root,COG0642@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase,Response_reg,SpoIIE
k59_18486_1	1265505.ATUG01000002_gene2535	3.78e-34	124.0	COG3637@1|root,COG3637@2|Bacteria,1N1ZM@1224|Proteobacteria,42U9G@68525|delta/epsilon subdivisions,2WSVE@28221|Deltaproteobacteria,2MMFF@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
k59_188949_1	1168034.FH5T_11540	4.4e-112	336.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia	976|Bacteroidetes	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_157995_1	203122.Sde_2598	2.26e-46	169.0	COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,466DS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,FG-GAP_2
k59_57308_1	1479237.JMLY01000001_gene904	7.94e-44	161.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465G3@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	mccA	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_111610_2	1473546.CH76_11350	1.74e-16	82.4	COG0654@1|root,COG0654@2|Bacteria,1UZNW@1239|Firmicutes,4IJW7@91061|Bacilli,3IY40@400634|Lysinibacillus	91061|Bacilli	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_80652_1	1123326.JFBL01000010_gene764	3.93e-16	88.2	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF,HD,HD_5,PAS_9,dCache_1
k59_96096_2	411490.ANACAC_00783	1.18e-73	243.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia	186801|Clostridia	S	Phage terminase, large subunit, PBSX family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k59_49590_1	929703.KE386491_gene113	1.01e-24	104.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_57319_1	1121403.AUCV01000003_gene1785	4.82e-48	164.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria	1224|Proteobacteria	D	involved in chromosome partitioning	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_150165_1	742766.HMPREF9455_00522	1.81e-18	84.3	COG5293@1|root,COG5293@2|Bacteria,4P0PX@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised protein conserved in bacteria (DUF2326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2326
k59_150165_2	742766.HMPREF9455_00521	2.63e-22	88.6	2E3PI@1|root,32YMM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150165_3	742766.HMPREF9455_00520	4.83e-11	63.5	COG0457@1|root,COG0457@2|Bacteria,4PNY7@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73290_1	595460.RRSWK_01941	1.45e-120	357.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_119911_1	1122179.KB890415_gene1927	1.98e-06	56.2	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
k59_181803_2	713587.THITH_06955	3.12e-65	209.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WXJB@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_220525_1	314275.MADE_1001145	1.63e-74	239.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,463ZX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_212635_1	686340.Metal_1114	1.19e-48	163.0	COG5464@1|root,COG5464@2|Bacteria,1R8FS@1224|Proteobacteria,1SC36@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
k59_212635_2	765912.Thimo_0462	2.1e-06	50.4	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,1S4QZ@1236|Gammaproteobacteria,1WY2C@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_3966_1	1227739.Hsw_2202	5.17e-05	52.0	COG2989@1|root,COG2989@2|Bacteria,4NI7M@976|Bacteroidetes,47X8Z@768503|Cytophagia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
k59_143179_1	1168034.FH5T_05030	8.7e-74	232.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,2FNJF@200643|Bacteroidia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k59_166374_1	1165841.SULAR_03582	9.66e-89	268.0	COG0589@1|root,COG0589@2|Bacteria,1PDMD@1224|Proteobacteria,43E6X@68525|delta/epsilon subdivisions,2YS51@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_65582_1	96561.Dole_3250	6.37e-69	225.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_189413_1	313596.RB2501_14859	1.83e-123	381.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_18944_1	1034943.BN1094_02853	1.19e-149	428.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1JCS7@118969|Legionellales	118969|Legionellales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_112189_1	1283076.M1IDH2_9CAUD	4e-11	66.2	4QAYA@10239|Viruses,4QVN5@35237|dsDNA viruses  no RNA stage,4QRZE@28883|Caudovirales,4QIAY@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_112189_3	69279.BG36_11075	4.14e-22	93.6	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,43JP8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
k59_112189_5	571.MC52_01580	1.16e-20	92.0	COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,1S2SY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	5'-deoxynucleotidase activity	yfdR	GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897	-	ko:K06952	-	-	-	-	ko00000	-	-	-	-
k59_96624_1	1165841.SULAR_08035	2.04e-65	199.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2YPG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_96624_2	1165841.SULAR_08030	2.88e-119	342.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2YMFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_243555_1	1168034.FH5T_11285	3.29e-96	286.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_73305_1	643867.Ftrac_0365	8.18e-116	362.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47U4M@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_204863_1	2340.JV46_16330	2.01e-48	168.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1J68F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_235935_1	2340.JV46_18560	1.57e-13	68.2	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1J762@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_235935_2	1249627.D779_2258	1.57e-55	181.0	COG0412@1|root,COG0412@2|Bacteria,1RCWF@1224|Proteobacteria,1RY38@1236|Gammaproteobacteria,1WX5X@135613|Chromatiales	135613|Chromatiales	Q	PFAM Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
k59_119925_1	566466.NOR53_2876	1.9e-36	142.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1J546@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ytfN	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_158457_1	1165841.SULAR_00370	5.24e-67	216.0	COG0790@1|root,COG0790@2|Bacteria,1Q4TH@1224|Proteobacteria,42ZV8@68525|delta/epsilon subdivisions,2YRWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60453_2	99158.XP_008881866.1	8.48e-24	98.6	COG1324@1|root,KOG3338@2759|Eukaryota,3YASR@5794|Apicomplexa,3YPHV@5796|Coccidia,3YVJ2@5809|Sarcocystidae	5794|Apicomplexa	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k59_192069_1	1168034.FH5T_12805	3.66e-98	305.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_44964_1	1286093.C266_10129	2.6e-21	94.0	COG4521@1|root,COG4521@2|Bacteria,1MVH2@1224|Proteobacteria,2VINJ@28216|Betaproteobacteria,1JZVK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	taurine ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
k59_76144_1	1121406.JAEX01000002_gene776	2.34e-33	125.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria,2M7XG@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
k59_76144_2	1038859.AXAU01000013_gene6584	4.03e-12	66.6	COG1653@1|root,COG1653@2|Bacteria,1MV8A@1224|Proteobacteria,2TTPV@28211|Alphaproteobacteria,3JT82@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	MA20_44770	-	-	ko:K17321	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	SBP_bac_1,SBP_bac_8
k59_207409_1	1121920.AUAU01000005_gene1008	3.86e-148	442.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_207411_1	714943.Mucpa_3687	1.14e-60	198.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1IS2R@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_83544_1	1165841.SULAR_03587	2.34e-74	246.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_230498_1	349521.HCH_00973	1.76e-61	194.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,1XJP7@135619|Oceanospirillales	135619|Oceanospirillales	K	AsnC family transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k59_230505_1	1165841.SULAR_09659	1.96e-110	341.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_52635_1	1168034.FH5T_04900	1.27e-68	220.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,2FR2H@200643|Bacteroidia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83548_1	1168034.FH5T_14150	2.22e-105	306.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,2FM4M@200643|Bacteroidia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_199999_1	381666.H16_A2693	9.3e-40	145.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VPHG@28216|Betaproteobacteria,1K230@119060|Burkholderiaceae	28216|Betaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
k59_246099_1	472759.Nhal_2889	1.47e-76	237.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1SEYJ@1236|Gammaproteobacteria,1X2JC@135613|Chromatiales	135613|Chromatiales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_238458_1	1042377.AFPJ01000009_gene188	1.11e-79	246.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,1RN43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Choloylglycine hydrolase	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_29672_1	765914.ThisiDRAFT_0666	3.02e-67	229.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_6455_1	765911.Thivi_3423	1.7e-08	61.6	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,1RXGJ@1236|Gammaproteobacteria,1WX7E@135613|Chromatiales	135613|Chromatiales	S	von Willebrand factor, type A	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	VWA_2
k59_238462_2	1429767.W6B150_9CAUD	1.11e-37	142.0	4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses  no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae	10744|Podoviridae	S	host cell wall	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_161055_1	457570.Nther_1888	2.62e-15	77.8	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia	186801|Clostridia	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_192094_1	1229783.C273_07302	0.000292	51.2	COG5384@1|root,COG5644@1|root,COG5384@2|Bacteria,COG5644@2|Bacteria	2|Bacteria	H	endopeptidase inhibitor activity	yddG	-	-	ko:K03201,ko:K13613	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko01004,ko01008,ko02044	3.A.7	-	-	CHU_C,IgGFc_binding,Laminin_G_3
k59_106741_1	768671.ThimaDRAFT_4728	3.13e-75	237.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1WWEJ@135613|Chromatiales	135613|Chromatiales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_106741_2	1249627.D779_1739	2e-23	91.3	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S765@1236|Gammaproteobacteria,1WYIN@135613|Chromatiales	135613|Chromatiales	C	PFAM Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
k59_60487_1	1517681.HW45_16300	2.63e-11	68.2	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XVT3@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_207436_1	1165841.SULAR_03247	1.03e-116	350.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_44986_1	1168034.FH5T_12410	2.66e-70	225.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FPY6@200643|Bacteroidia	976|Bacteroidetes	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
k59_230514_1	1168034.FH5T_07155	2.24e-44	151.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367,LolA,LolA_like
k59_122602_1	1121897.AUGO01000011_gene3102	5.37e-60	200.0	COG0688@1|root,COG0688@2|Bacteria,4NHWY@976|Bacteroidetes,1IIB5@117743|Flavobacteriia	976|Bacteroidetes	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_22086_1	2340.JV46_15520	2.77e-62	201.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_22086_2	2340.JV46_15510	4.02e-30	114.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_246479_2	62928.azo1585	0.000881	41.6	2DT7R@1|root,33J2W@2|Bacteria,1NQ33@1224|Proteobacteria,2VXQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45359_1	1121423.JONT01000040_gene23	2.59e-58	188.0	COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,25E75@186801|Clostridia,261FA@186807|Peptococcaceae	186801|Clostridia	L	PFAM D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
k59_169577_1	487796.Flav2ADRAFT_1109	3.89e-20	85.1	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia	976|Bacteroidetes	J	Methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_169577_2	313596.RB2501_03370	2.63e-36	133.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia	976|Bacteroidetes	FH	Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
k59_192504_1	501479.ACNW01000062_gene2740	1.07e-62	210.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_207859_1	398578.Daci_3799	3.27e-39	152.0	COG1672@1|root,COG1672@2|Bacteria,1NIID@1224|Proteobacteria,2W5ZH@28216|Betaproteobacteria,4AIPY@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_176767_1	2002.JOEQ01000031_gene1609	6.39e-06	54.7	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria,4EMBQ@85012|Streptosporangiales	201174|Actinobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	ppsE	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030312,GO:0032787,GO:0032991,GO:0034081,GO:0042546,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:0072330,GO:1901576	-	ko:K12444	-	-	-	-	ko00000,ko01004	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,MFS_1,PP-binding,Thioesterase,ketoacyl-synt
k59_215554_1	71139.XP_010026055.1	8.75e-09	58.5	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta	35493|Streptophyta	E	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	G-patch,RVT_1,RVT_3,Retrotrans_gag,rve
k59_146553_1	29730.Gorai.001G166300.1	3.57e-137	404.0	COG1008@1|root,KOG4845@2759|Eukaryota,37KP8@33090|Viridiplantae,3GEAS@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	nad4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03881	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_169585_1	387093.SUN_0523	5.71e-173	489.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YMUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_184784_1	247634.GPB2148_990	2.72e-52	185.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_192510_1	1165841.SULAR_06968	9.12e-50	168.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_192510_2	1165841.SULAR_06963	5.1e-198	554.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_6795_1	84531.JMTZ01000039_gene556	3.07e-85	263.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,1RS0F@1236|Gammaproteobacteria,1XA8K@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
k59_99728_1	1168034.FH5T_09960	6.8e-36	132.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,2FPNB@200643|Bacteroidia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
k59_192512_2	1206739.BAGJ01000011_gene3410	6.44e-26	110.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4FTYI@85025|Nocardiaceae	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
k59_115042_1	1502852.FG94_04632	3.5e-19	87.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,474SI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glucose-regulated metallo-peptidase M90	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_60883_1	395493.BegalDRAFT_1762	4.44e-47	166.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,45ZYF@72273|Thiotrichales	72273|Thiotrichales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_176777_1	1229487.AMYW01000002_gene1663	1.75e-10	66.6	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,4NF3Q@976|Bacteroidetes,1ICW9@117743|Flavobacteriia,2NVJJ@237|Flavobacterium	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_146565_1	1165841.SULAR_02943	6.75e-144	413.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_207864_1	2340.JV46_17550	1.57e-126	371.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1J4KI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_223421_1	1165841.SULAR_10629	6.03e-70	213.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2YNVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k59_223421_2	1165841.SULAR_10634	7.69e-59	181.0	COG2921@1|root,COG2921@2|Bacteria,1Q61R@1224|Proteobacteria,43A9V@68525|delta/epsilon subdivisions,2YQV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
k59_238935_1	215803.DB30_6645	5.9e-38	146.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2Z2WC@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_146566_1	1229780.BN381_380002	5.86e-60	200.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k59_246498_2	313612.L8106_04936	9.82e-42	151.0	COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,1G38Q@1117|Cyanobacteria,1HACP@1150|Oscillatoriales	1117|Cyanobacteria	H	Mycolic acid cyclopropane synthetase	sdmt	GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052729,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.1.1.157,2.1.1.161	ko:K13042,ko:K18897	ko00260,map00260	-	R07244,R10061	RC00003,RC00496,RC03040	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11
k59_60886_1	1453496.AT03_06660	2.27e-119	359.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	asparagine synthase, glutamine-hydrolyzing	asnB	GO:0000166,GO:0003674,GO:0003824,GO:0004066,GO:0004071,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006541,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016054,GO:0016211,GO:0016597,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0017076,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	iB21_1397.B21_00622,iECBD_1354.ECBD_2988,iECB_1328.ECB_00631,iECD_1391.ECD_00631,iEcHS_1320.EcHS_A0717,iEcolC_1368.EcolC_2982,iSF_1195.SF0619	Asn_synthase,GATase_7
k59_83977_1	1279017.AQYJ01000029_gene3816	1.55e-48	171.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,466GP@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	lprN	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_123032_2	95619.PM1_0220870	6.15e-40	140.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1S0IN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	IV02_26825	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_184794_1	1236542.BALM01000012_gene3580	1.05e-110	322.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	2-methylcitrate dehydratase	prpD	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0047547,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0072329,GO:1901575	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	iEcolC_1368.EcolC_3291	MmgE_PrpD
k59_83981_1	240016.ABIZ01000001_gene4797	3.31e-46	165.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_234504_2	1165841.SULAR_08577	7.77e-52	169.0	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_133714_1	1408473.JHXO01000007_gene707	2.77e-58	187.0	COG0785@1|root,COG0785@2|Bacteria,4PKGI@976|Bacteroidetes,2G3GF@200643|Bacteroidia	976|Bacteroidetes	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
k59_133714_2	485915.Dret_1783	1.84e-11	65.5	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria,2M8CG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_79664_1	1165841.SULAR_09009	8.24e-08	52.8	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_79664_2	387093.SUN_0490	2.73e-40	138.0	COG1331@1|root,COG1331@2|Bacteria,1QZ2A@1224|Proteobacteria,43CEH@68525|delta/epsilon subdivisions,2YQRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_164795_1	313596.RB2501_05185	2.62e-106	320.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HYK4@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_133719_1	485918.Cpin_3805	7.01e-09	61.6	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,DUF4849
k59_95143_1	530564.Psta_3081	2.63e-11	65.9	COG1520@1|root,COG1520@2|Bacteria,2IWVJ@203682|Planctomycetes	203682|Planctomycetes	S	WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_195728_1	1168034.FH5T_17445	6.95e-22	90.9	2C0BR@1|root,302EW@2|Bacteria,4P9SR@976|Bacteroidetes,2FQUQ@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
k59_79665_1	1123400.KB904770_gene2734	2.86e-30	119.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
k59_87256_1	387093.SUN_0014	2.53e-96	296.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_102715_1	349521.HCH_06182	2.88e-59	190.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1XKC8@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_110585_1	1499689.CCNN01000007_gene923	3.49e-07	53.1	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,24F7N@186801|Clostridia,36FVY@31979|Clostridiaceae	186801|Clostridia	KT	regulator	bltR	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
k59_110585_2	1218074.BAXZ01000014_gene3062	2.81e-45	160.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI85@28216|Betaproteobacteria,1K241@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	dld	-	1.1.2.4,1.1.5.12	ko:K00102,ko:K03777	ko00620,ko01120,map00620,map01120	-	R00197,R00704,R11591	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_211083_1	395493.BegalDRAFT_0703	0.000198	50.4	COG1216@1|root,COG3551@1|root,COG4627@1|root,COG1216@2|Bacteria,COG3551@2|Bacteria,COG4627@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria,46246@72273|Thiotrichales	72273|Thiotrichales	M	glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_187980_1	215803.DB30_7683	8.3e-24	100.0	COG1999@1|root,COG1999@2|Bacteria,1R9EM@1224|Proteobacteria,42N5F@68525|delta/epsilon subdivisions,2WKG7@28221|Deltaproteobacteria,2YV22@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
k59_234507_1	3880.AES58602	3.1e-63	222.0	COG1005@1|root,COG3344@1|root,KOG4768@2759|Eukaryota,KOG4770@2759|Eukaryota,37KUX@33090|Viridiplantae,3GHBI@35493|Streptophyta,4JTJX@91835|fabids	35493|Streptophyta	A	NADH dehydrogenase (quinone) activity	matR	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2
k59_2383_1	289377.HL41_04235	4.39e-09	54.7	COG0828@1|root,COG0828@2|Bacteria,2GI0S@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_2383_2	351348.Maqu_1762	4.83e-05	45.4	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,464B7@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_149130_1	395493.BegalDRAFT_1677	1.47e-63	215.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent Clp protease ATP-binding subunit ClpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_195746_1	795359.TOPB45_0970	2.99e-15	80.1	COG2204@1|root,COG2204@2|Bacteria,2GH04@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_187982_1	1129194.I3PH11_9CAUD	7.03e-21	87.0	4QAVB@10239|Viruses,4QVA0@35237|dsDNA viruses  no RNA stage,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae	10662|Myoviridae	S	defense response to bacterium	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56392_1	266264.Rmet_2562	3.89e-30	117.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,1K0X8@119060|Burkholderiaceae	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	PP2C_2
k59_48685_1	948565.AFFP02000030_gene1189	1.02e-37	129.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1Y8MZ@135625|Pasteurellales	135625|Pasteurellales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_48685_2	396588.Tgr7_2304	2.91e-65	211.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales	135613|Chromatiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_41050_1	903818.KI912268_gene1402	4.81e-91	279.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_234964_2	864702.OsccyDRAFT_4357	7.46e-21	90.1	COG1981@1|root,COG1981@2|Bacteria,1G18U@1117|Cyanobacteria,1H8D3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_56764_1	351348.Maqu_4229	1.81e-91	283.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,468B0@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_172921_2	522772.Dacet_1866	7.99e-11	67.4	COG3328@1|root,COG3328@2|Bacteria,2GGBW@200930|Deferribacteres	2|Bacteria	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_126607_1	521674.Plim_1602	3.34e-21	99.8	COG3209@1|root,COG3209@2|Bacteria,2IY61@203682|Planctomycetes	203682|Planctomycetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_149619_1	78398.KS43_02130	3.9e-07	53.9	COG2334@1|root,COG2334@2|Bacteria,1MXTW@1224|Proteobacteria,1RY9U@1236|Gammaproteobacteria,1MPXB@122277|Pectobacterium	1236|Gammaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_226972_1	395493.BegalDRAFT_3357	1.5e-33	129.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,1RNUW@1236|Gammaproteobacteria,463EF@72273|Thiotrichales	1224|Proteobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
k59_103198_1	387093.SUN_1699	2.41e-66	209.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_33941_1	517417.Cpar_0144	5.07e-46	159.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07340,ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,LprI,NfeD,SDH_sah
k59_196271_1	1165841.SULAR_00235	8.28e-107	310.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2YPAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
k59_33943_1	1238190.AMQY01000023_gene144	1.41e-12	73.2	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XHB0@135619|Oceanospirillales	135619|Oceanospirillales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,AAA_30,UvrD_C_2
k59_95620_1	397945.Aave_3359	3.72e-101	314.0	COG0286@1|root,COG5502@1|root,COG0286@2|Bacteria,COG5502@2|Bacteria,1MW3A@1224|Proteobacteria,2VK6V@28216|Betaproteobacteria,4ABV9@80864|Comamonadaceae	28216|Betaproteobacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_180779_1	264402.Cagra.5120s0021.1.p	2.59e-106	317.0	COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,3GF4E@35493|Streptophyta	35493|Streptophyta	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis	cob	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_196272_1	519989.ECTPHS_01944	1.01e-16	79.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales	135613|Chromatiales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
k59_196272_2	395493.BegalDRAFT_2974	1.38e-44	152.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S364@1236|Gammaproteobacteria,463EC@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_157423_1	1165841.SULAR_00165	2.68e-166	468.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2YMZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_103202_1	1173022.Cri9333_4331	2.25e-71	244.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,Pkinase,Response_reg
k59_80132_1	313603.FB2170_10319	4.79e-71	233.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1I4ES@117743|Flavobacteriia	976|Bacteroidetes	P	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
k59_56784_1	1165841.SULAR_09029	3.66e-49	157.0	COG0721@1|root,COG0721@2|Bacteria,1Q61J@1224|Proteobacteria,42VIQ@68525|delta/epsilon subdivisions,2YQAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_56784_2	1442598.JABW01000005_gene448	1.96e-38	132.0	COG1393@1|root,COG1393@2|Bacteria,1QDI7@1224|Proteobacteria,42U8X@68525|delta/epsilon subdivisions,2YPXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_56784_3	1165841.SULAR_09039	1.42e-35	129.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_196280_1	1123400.KB904746_gene1234	7.16e-39	148.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,45ZW5@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
k59_80136_1	247634.GPB2148_430	1.86e-103	307.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1J4Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_149627_1	395493.BegalDRAFT_2072	1.86e-64	204.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,460GC@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_33952_1	639283.Snov_1999	3.24e-05	46.2	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYZQ@28211|Alphaproteobacteria,3F19F@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,PAS_9,Response_reg
k59_49055_1	551275.KB899546_gene2302	2.79e-55	196.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,2VEV5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_242569_1	207954.MED92_18218	1.59e-41	149.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XH84@135619|Oceanospirillales	135619|Oceanospirillales	E	D-amino acid	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_242569_2	1157708.KB907460_gene1351	9.83e-11	61.6	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,2VVPQ@28216|Betaproteobacteria,4AFBC@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Pilus assembly protein	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k59_172933_1	1249627.D779_0023	1.7e-33	136.0	COG3591@1|root,COG5640@1|root,COG3591@2|Bacteria,COG5640@2|Bacteria,1RFR4@1224|Proteobacteria,1SZFK@1236|Gammaproteobacteria,1X18M@135613|Chromatiales	135613|Chromatiales	EO	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
k59_242573_1	572480.Arnit_1228	5.52e-99	304.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2YTEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_126619_1	1165841.SULAR_00865	4.64e-18	81.3	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,42RPB@68525|delta/epsilon subdivisions,2YP5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_126619_2	1165841.SULAR_00860	8.49e-147	416.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_49067_1	204669.Acid345_1066	1.85e-05	52.0	COG1404@1|root,COG1409@1|root,COG3055@1|root,COG3291@1|root,COG3386@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria,2JMMV@204432|Acidobacteriia	204432|Acidobacteriia	GO	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH
k59_203854_1	97139.C824_04896	2.99e-07	52.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,36DD3@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_203854_2	1168034.FH5T_09710	1.03e-93	296.0	COG1287@1|root,COG1287@2|Bacteria,4NUWQ@976|Bacteroidetes	976|Bacteroidetes	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_226998_1	1165841.SULAR_07630	4.02e-22	94.4	COG2888@1|root,COG2888@2|Bacteria,1MZH3@1224|Proteobacteria,42VBG@68525|delta/epsilon subdivisions,2YR8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_226998_2	1165841.SULAR_07635	1.09e-124	370.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_2865_1	1168034.FH5T_11175	1.39e-22	93.2	2EJIX@1|root,33D9U@2|Bacteria,4NXKW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2865_2	1168034.FH5T_11180	2.18e-100	292.0	COG1595@1|root,COG1595@2|Bacteria,4NETF@976|Bacteroidetes,2FNPY@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_199636_1	420662.Mpe_A1439	3.39e-45	161.0	COG3596@1|root,COG3596@2|Bacteria,1R01T@1224|Proteobacteria,2WHSI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
k59_13591_1	635013.TherJR_1461	1.48e-104	319.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_199639_1	1168034.FH5T_11305	1.62e-34	128.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,2FN2X@200643|Bacteroidia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_199639_2	1168034.FH5T_11310	1.99e-72	224.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_222696_2	497964.CfE428DRAFT_0155	9.79e-25	106.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,46TEA@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116,polyprenyl_synt
k59_214898_1	1379858.N508_02106	2.16e-10	66.6	COG4775@1|root,COG4775@2|Bacteria,2GFAK@200930|Deferribacteres	200930|Deferribacteres	M	surface antigen (D15)	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_29261_1	234267.Acid_5307	4.07e-37	143.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria	57723|Acidobacteria	C	2-oxoglutarate dehydrogenase, E1	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_199642_1	1172190.M947_11250	2.43e-58	188.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42TAC@68525|delta/epsilon subdivisions,2YRI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG2518 Protein-L-isoaspartate carboxylmethyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_60115_1	1254432.SCE1572_26550	7.73e-44	154.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_29264_1	1300345.LF41_881	4.53e-05	50.4	2DKZK@1|root,310GY@2|Bacteria,1NQ6H@1224|Proteobacteria,1SSKG@1236|Gammaproteobacteria,1X6D8@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
k59_13598_1	83406.HDN1F_38000	4.15e-13	69.7	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1J4Z2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
k59_106387_1	1168034.FH5T_10080	4.21e-111	327.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_60124_1	1049564.TevJSym_ae00950	3.43e-37	128.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,1J6VI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulators	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,LMWPc
k59_60124_2	1049564.TevJSym_ae00930	1.31e-17	80.9	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4CK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_37708_2	1122611.KB903952_gene6090	0.000708	43.1	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
k59_137897_1	994573.T472_0212665	6.51e-32	121.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,36DUE@31979|Clostridiaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_146297_1	468059.AUHA01000002_gene107	5.11e-48	172.0	COG0457@1|root,COG4191@1|root,COG0457@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1IQBI@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12
k59_122764_1	936455.KI421499_gene4387	9.29e-43	149.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria,3JV19@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha beta hydrolase	MA20_16655	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DUF676,Hydrolase_4
k59_29861_1	1121875.KB907550_gene701	1.35e-74	232.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1HXMG@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_161246_1	395493.BegalDRAFT_0703	1.41e-67	237.0	COG1216@1|root,COG3551@1|root,COG4627@1|root,COG1216@2|Bacteria,COG3551@2|Bacteria,COG4627@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria,46246@72273|Thiotrichales	72273|Thiotrichales	M	glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_192266_1	387093.SUN_0470	1.12e-70	220.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2YNS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_114867_1	521674.Plim_0823	4e-14	77.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_207595_1	391625.PPSIR1_42124	7.56e-40	147.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_45178_1	714961.BFZC1_22427	5.78e-13	75.1	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3IWSZ@400634|Lysinibacillus	91061|Bacilli	L	ATP-dependent DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_45179_2	1168034.FH5T_04380	3.06e-33	124.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,2FW97@200643|Bacteroidia	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_169385_1	1165841.SULAR_08472	6.54e-87	273.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42ZC0@68525|delta/epsilon subdivisions,2YR4G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_169385_2	387093.SUN_2288	8.31e-23	93.6	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2YMHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_37722_1	156889.Mmc1_3161	4.99e-85	278.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006855,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015238,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015307,GO:0015318,GO:0015672,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902495,GO:1902600,GO:1990281,GO:1990351	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_146304_1	1123400.KB904746_gene1329	7.4e-13	70.1	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,1S4XC@1236|Gammaproteobacteria,462P1@72273|Thiotrichales	72273|Thiotrichales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_146304_2	1123033.ARNF01000047_gene2012	1.13e-14	78.6	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,1RY3G@1236|Gammaproteobacteria,3NM79@468|Moraxellaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF898)	yjgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF898
k59_122769_1	589865.DaAHT2_2376	2.31e-61	206.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MJGB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
k59_230649_1	1165841.SULAR_10249	1.75e-30	112.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2YNU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_230649_2	1165841.SULAR_10244	8.15e-55	175.0	COG1514@1|root,COG1514@2|Bacteria,1Q2AV@1224|Proteobacteria,42VB6@68525|delta/epsilon subdivisions,2YQIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	2'-5' RNA ligase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k59_246314_1	1195246.AGRI_13530	8.63e-30	107.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,468FU@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_246314_2	243233.MCA2992	7.19e-07	49.3	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1XF5X@135618|Methylococcales	135618|Methylococcales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_137917_1	489825.LYNGBM3L_23640	3.5e-50	182.0	28HMZ@1|root,2Z7WD@2|Bacteria,1G31X@1117|Cyanobacteria	2|Bacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_207606_1	1165841.SULAR_01773	9.51e-114	338.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_169391_1	2340.JV46_28000	1.79e-75	233.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1J545@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_169391_2	2340.JV46_27980	2.57e-20	82.8	2EHQ5@1|root,33BFX@2|Bacteria,1NJW1@1224|Proteobacteria,1SHMS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
k59_169391_3	2340.JV46_27920	1.11e-111	325.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_153420_1	1123035.ARLA01000028_gene2142	4.84e-34	134.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1HWWX@117743|Flavobacteriia,4C3HI@83612|Psychroflexus	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
k59_223263_1	395493.BegalDRAFT_1705	7.95e-67	223.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,461IW@72273|Thiotrichales	72273|Thiotrichales	N	Gliding motility protein GldG	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_37725_2	3694.POPTR_0019s08360.1	1.13e-13	72.0	KOG1075@1|root,KOG1075@2759|Eukaryota,37TIF@33090|Viridiplantae,3G9IZ@35493|Streptophyta,4JJZN@91835|fabids	35493|Streptophyta	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,RVT_1,RVT_3,zf-RVT
k59_192288_1	1150599.MPHLEI_02788	2.39e-05	52.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
k59_6638_2	1118054.CAGW01000017_gene4395	7.85e-50	168.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,26TCW@186822|Paenibacillaceae	91061|Bacilli	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_122793_1	1408813.AYMG01000001_gene3747	1.33e-83	269.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQPI@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_223266_1	1165841.SULAR_05733	1.82e-111	327.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_192292_1	1122138.AQUZ01000020_gene8301	1.91e-34	133.0	COG3356@1|root,COG3356@2|Bacteria,2I6IM@201174|Actinobacteria,4DW56@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
k59_184628_1	1168034.FH5T_13840	2.98e-13	65.1	COG0011@1|root,COG0011@2|Bacteria	2|Bacteria	H	TIGRFAM Protein of	M1-594	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_184628_2	1168034.FH5T_01045	3.94e-68	214.0	COG2207@1|root,COG2207@2|Bacteria,4NMFW@976|Bacteroidetes,2G07E@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k59_106929_1	1249627.D779_2665	1.05e-18	84.7	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1WVY7@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_192297_1	313596.RB2501_06440	1.17e-114	336.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_99527_1	338966.Ppro_3331	8.17e-21	100.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,43TUT@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
k59_246330_1	266264.Rmet_2212	0.00077	44.7	COG0589@1|root,COG0589@2|Bacteria,1PUQK@1224|Proteobacteria,2VT3N@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	uspE	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_200169_1	1168034.FH5T_07850	1.39e-38	140.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,2FKYU@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_200169_2	1168034.FH5T_07845	9.91e-37	135.0	COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes,2FS7M@200643|Bacteroidia	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
k59_91545_1	2340.JV46_27870	1.17e-71	220.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1J5PX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
k59_91547_2	1202962.KB907150_gene1942	1.78e-95	282.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_29887_1	716928.AJQT01000068_gene3393	2.03e-62	213.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_169413_1	518766.Rmar_1649	8.46e-91	284.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1FIXE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_91552_1	595460.RRSWK_00866	2.36e-18	88.6	COG0517@1|root,COG0517@2|Bacteria,2J27U@203682|Planctomycetes	203682|Planctomycetes	S	Best DB hits BLAST	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_161263_2	258533.BN977_00748	4.52e-16	79.3	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,234DB@1762|Mycobacteriaceae	201174|Actinobacteria	CG	PFAM UDP-glucuronosyl UDP-glucosyltransferase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	-	-	-	-	-	-	-	-	-	UDPGT
k59_68523_1	1168034.FH5T_05820	4.09e-39	146.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,2FQ2M@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase, M28 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_161264_1	387093.SUN_1801	8.81e-42	145.0	COG2515@1|root,COG2515@2|Bacteria,1R87T@1224|Proteobacteria,42MPC@68525|delta/epsilon subdivisions,2YN3K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	1-aminocyclopropane-1-carboxylate deaminase	acd	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	-
k59_161264_2	1367491.BN865_08710	8.87e-06	46.6	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2YMEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_230669_1	582899.Hden_0689	6.25e-119	343.0	COG1150@1|root,COG1150@2|Bacteria,1R7PH@1224|Proteobacteria,2U2FE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_8
k59_230669_2	717785.HYPMC_2223	0.000163	42.0	COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,2UB97@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_146334_1	3659.XP_004168533.1	2.06e-107	323.0	COG0090@1|root,KOG0438@2759|Eukaryota,37TIQ@33090|Viridiplantae,3GHDG@35493|Streptophyta,4JS8D@91835|fabids	35493|Streptophyta	J	Ribosomal protein L2	-	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L2
k59_2210_1	1168034.FH5T_11970	4.26e-63	199.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,2FMJG@200643|Bacteroidia	976|Bacteroidetes	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_156725_1	1121935.AQXX01000128_gene1845	1.86e-82	263.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1XJG7@135619|Oceanospirillales	135619|Oceanospirillales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_156725_2	1129794.C427_4182	3.2e-11	62.8	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,463Z5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_210930_1	1123401.JHYQ01000003_gene2169	8.55e-81	244.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,460FE@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_203223_1	1168034.FH5T_12670	1.82e-45	159.0	COG3291@1|root,COG3291@2|Bacteria,4NU2U@976|Bacteroidetes,2FNZM@200643|Bacteroidia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_87147_1	742766.HMPREF9455_03537	2.82e-80	248.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,2FN7F@200643|Bacteroidia,22X45@171551|Porphyromonadaceae	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
k59_48539_1	649638.Trad_2691	8.82e-90	280.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_234361_2	1357399.HMPREF2087_01065	3.83e-52	173.0	COG0500@1|root,COG2226@2|Bacteria,1RKTD@1224|Proteobacteria,42N8D@68525|delta/epsilon subdivisions,2YNJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_203231_1	3711.Bra030817.1-P	0.000105	47.8	28KI5@1|root,2QSZG@2759|Eukaryota,37PV7@33090|Viridiplantae,3G7KY@35493|Streptophyta,3HY7W@3699|Brassicales	35493|Streptophyta	S	Tetratricopeptide repeats	-	-	-	ko:K21991	-	-	-	-	ko00000,ko03110	-	-	-	TPR_16,TPR_19,TPR_8
k59_156735_1	313596.RB2501_08590	9.26e-47	159.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HXME@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_156735_2	313596.RB2501_08585	5.98e-50	176.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_56241_1	1469607.KK073768_gene346	1.96e-13	70.5	COG2931@1|root,COG3540@1|root,COG4222@1|root,COG4247@1|root,COG2931@2|Bacteria,COG3540@2|Bacteria,COG4222@2|Bacteria,COG4247@2|Bacteria,1G00S@1117|Cyanobacteria,1HIY4@1161|Nostocales	1117|Cyanobacteria	I	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	-	-	3.1.3.1,3.1.3.8,3.1.4.46	ko:K01083,ko:K01113,ko:K01126	ko00562,ko00564,ko00790,ko01100,ko02020,map00562,map00564,map00790,map01100,map02020	M00126	R01030,R01470,R03371,R04620	RC00017,RC00078,RC00425	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4114,Exo_endo_phos,GDPD,HemolysinCabind,PhoD,PhoD_N,Phytase,Phytase-like,SurE
k59_157149_2	218851.Aquca_013_00240.1	5.21e-19	88.6	KOG0039@1|root,KOG0039@2759|Eukaryota,37IDX@33090|Viridiplantae,3G80X@35493|Streptophyta	35493|Streptophyta	PQ	ferric reduction oxidase	-	GO:0000293,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0015688,GO:0016020,GO:0016491,GO:0016722,GO:0016723,GO:0042592,GO:0043207,GO:0044464,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771,GO:1901678	1.16.1.7	ko:K00521	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_6
k59_219132_2	1286632.P278_19330	2.23e-58	183.0	COG2963@1|root,COG2963@2|Bacteria,4NPRF@976|Bacteroidetes,1I2EZ@117743|Flavobacteriia	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_126390_1	755732.Fluta_0949	5.8e-112	341.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia,2PARA@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_25681_1	768671.ThimaDRAFT_4355	2.61e-49	175.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,1SKFJ@1236|Gammaproteobacteria,1X099@135613|Chromatiales	135613|Chromatiales	L	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_87489_2	1537917.JU82_01000	1.06e-50	181.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_133939_1	1168034.FH5T_12035	1.38e-67	228.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,2FVX6@200643|Bacteroidia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_165018_1	521098.Aaci_0737	1.39e-69	231.0	COG0213@1|root,COG0295@1|root,COG0213@2|Bacteria,COG0295@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,278UM@186823|Alicyclobacillaceae	91061|Bacilli	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k59_219136_1	1121288.AULL01000010_gene1263	8.87e-50	171.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,1I03U@117743|Flavobacteriia,3ZNR0@59732|Chryseobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k59_64352_2	1121405.dsmv_1211	2.01e-31	121.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42NA7@68525|delta/epsilon subdivisions,2WIN5@28221|Deltaproteobacteria,2MJ30@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k59_17732_1	443143.GM18_2493	1.06e-22	99.8	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_17732_2	319224.Sputcn32_3564	1.81e-06	49.7	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,2QBMZ@267890|Shewanellaceae	1236|Gammaproteobacteria	U	TIGRFAM general secretion pathway protein G	gspG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_133946_1	1121937.AUHJ01000012_gene2721	2.65e-91	283.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RSC1@1236|Gammaproteobacteria,469U9@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_242350_1	1117318.PRUB_21822	1.77e-39	149.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,2PZQP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303,ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iPC815.YPO0158	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_64358_1	1123228.AUIH01000007_gene2598	1.56e-50	173.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales	135619|Oceanospirillales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_165040_2	370438.PTH_1843	5.5e-10	58.2	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,261UI@186807|Peptococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_211289_1	1168034.FH5T_10830	1.21e-51	166.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_211289_2	1168034.FH5T_10835	9.44e-36	125.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,2FN5J@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_25696_1	760192.Halhy_1528	0.0004	45.4	COG1487@1|root,COG1487@2|Bacteria,4NV71@976|Bacteroidetes	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_33710_1	1500893.JQNB01000001_gene2540	1.22e-48	174.0	COG3533@1|root,COG3533@2|Bacteria,1MWEN@1224|Proteobacteria,1RSMM@1236|Gammaproteobacteria,1X332@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
k59_87501_1	1469607.KK073768_gene3290	4.95e-86	286.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HJVE@1161|Nostocales	1117|Cyanobacteria	Q	COGs COG3321 Polyketide synthase modules and related protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
k59_95413_1	1165841.SULAR_10369	3.93e-184	550.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_157172_2	472759.Nhal_3012	5.34e-23	89.7	COG2442@1|root,COG2442@2|Bacteria,1N96I@1224|Proteobacteria,1SHY0@1236|Gammaproteobacteria,1X23V@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
k59_110778_1	118168.MC7420_4451	1.1e-30	125.0	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG3850@1|root,COG4191@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHXQ@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_10393_1	938709.AUSH02000031_gene1359	2.13e-52	186.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes	976|Bacteroidetes	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_17755_1	1187848.AJYQ01000005_gene345	4.82e-76	238.0	COG0031@1|root,COG0031@2|Bacteria,1MUR6@1224|Proteobacteria,1RMS1@1236|Gammaproteobacteria,1XUZT@135623|Vibrionales	135623|Vibrionales	E	Cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_219163_1	530564.Psta_2654	7.38e-22	98.6	COG2304@1|root,COG2304@2|Bacteria,2IYCF@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_3
k59_64368_1	1198452.Jab_2c09860	7.61e-48	155.0	COG0346@1|root,COG0346@2|Bacteria,1MZQY@1224|Proteobacteria,2VT5S@28216|Betaproteobacteria,477JY@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_48849_1	525898.Sdel_1131	2.81e-24	100.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2YMGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_48849_2	1165841.SULAR_04868	5.83e-84	263.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_149415_2	102125.Xen7305DRAFT_00022690	1.12e-118	345.0	COG1662@1|root,COG3677@1|root,COG1662@2|Bacteria,COG3677@2|Bacteria,1G617@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_41289_1	1165841.SULAR_07645	3.46e-123	363.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,42P2P@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	phosphotransferase system, EIIB	nagE	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0015764,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0090563,GO:0090586,GO:1901264	2.7.1.193	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	iECP_1309.ECP_0691	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k59_141743_1	406817.XNC1_3880	9.19e-51	171.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_141743_2	1073999.BN137_2638	1.1e-10	63.5	COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,1RND9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	UPF0283 membrane protein	ycjF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08990	-	-	-	-	ko00000	-	-	-	DUF697
k59_33727_1	28532.XP_010528252.1	2.12e-40	150.0	COG0265@1|root,KOG1320@2759|Eukaryota,37NI3@33090|Viridiplantae,3G8QG@35493|Streptophyta,3HT3Z@3699|Brassicales	35493|Streptophyta	O	Protease Do-like 1, chloroplastic	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006091,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009719,GO:0009725,GO:0009735,GO:0009765,GO:0009987,GO:0010033,GO:0010206,GO:0015979,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031976,GO:0031977,GO:0031984,GO:0034357,GO:0042221,GO:0042651,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_87522_1	1198232.CYCME_0904	2.28e-66	216.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,460CG@72273|Thiotrichales	72273|Thiotrichales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
k59_234770_1	1121405.dsmv_2856	4.33e-55	191.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_196041_1	1049564.TevJSym_aa02310	1.69e-104	313.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1J4D1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_188261_1	1165841.SULAR_04417	7.64e-111	335.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_180552_1	1165841.SULAR_05663	1.03e-94	284.0	COG1729@1|root,COG1729@2|Bacteria,1NG81@1224|Proteobacteria,42R1Z@68525|delta/epsilon subdivisions,2YNY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	repeat protein	ybgF	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6
k59_56594_1	1122986.KB908331_gene2154	0.00013	44.3	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,2FKYH@200643|Bacteroidia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_25718_1	265072.Mfla_0738	4.37e-17	73.6	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,2KN2F@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_25718_2	857087.Metme_4122	5.71e-69	213.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XF6D@135618|Methylococcales	135618|Methylococcales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_203646_1	416269.APL_0218	1.53e-47	168.0	2DBF1@1|root,2Z8VU@2|Bacteria,1MV31@1224|Proteobacteria,1RSDF@1236|Gammaproteobacteria,1Y8CH@135625|Pasteurellales	135625|Pasteurellales	S	CRISPR-associated protein (Cas_Csy1)	-	-	-	ko:K19127	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csy1
k59_242368_1	876044.IMCC3088_166	2e-43	161.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1J4ZY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional accessory protein	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_95425_1	1131269.AQVV01000013_gene1719	3.12e-67	219.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	AAA_22,Epimerase_2
k59_95425_2	13249.RPRC009321-PA	2.93e-22	101.0	COG0438@1|root,KOG1111@2759|Eukaryota	2759|Eukaryota	M	phosphatidylinositol N-acetylglucosaminyltransferase activity	-	-	2.4.1.198	ko:K03857	ko00563,ko01100,map00563,map01100	M00065	R05916	-	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_95429_2	1318628.MARLIPOL_14655	3.76e-06	50.1	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S1KB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_79967_1	65393.PCC7424_5718	5.29e-95	289.0	COG3385@1|root,COG3385@2|Bacteria,1G27F@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_180562_1	448385.sce8281	1.34e-41	149.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YYIW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_79968_1	1250232.JQNJ01000001_gene2815	1.5e-32	120.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1HXP0@117743|Flavobacteriia	976|Bacteroidetes	Q	Organic solvent ABC transporter ATP-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_79968_2	1121012.AUKX01000003_gene1515	6.48e-31	115.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1HX62@117743|Flavobacteriia,23H53@178469|Arenibacter	976|Bacteroidetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_219182_1	563040.Saut_1715	5.35e-47	158.0	COG0745@1|root,COG0745@2|Bacteria,1Q6G8@1224|Proteobacteria,42T3T@68525|delta/epsilon subdivisions,2YPQK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_196058_1	1347393.HG726021_gene295	1.19e-46	163.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_5,Abhydrolase_6,Hydrolase_4
k59_10422_1	56780.SYN_02257	2.11e-169	492.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,43AEI@68525|delta/epsilon subdivisions,2X5UC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Alpha amylase	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_192031_2	2340.JV46_10180	1.88e-38	130.0	2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,1SGKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76449_1	1046714.AMRX01000006_gene2346	0.000131	53.5	COG2372@1|root,COG5276@1|root,COG2372@2|Bacteria,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria,46D9Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
k59_230795_1	1049564.TevJSym_aa00990	4.88e-06	48.1	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1J55N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NT	Chemotaxis protein histidine kinase	cheA	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
k59_230795_2	395493.BegalDRAFT_1550	4.28e-55	174.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,462JU@72273|Thiotrichales	72273|Thiotrichales	KT	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_169519_1	983544.Lacal_2950	1.49e-38	140.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,4PKKU@976|Bacteroidetes,1IJC1@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
k59_169519_2	1250232.JQNJ01000001_gene3613	8.5e-26	102.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_230796_1	1168034.FH5T_15140	6.91e-133	392.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_184746_1	1121875.KB907546_gene2504	2.09e-150	431.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,1I2DE@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Fn3_assoc,Metallophos,PA14
k59_91644_1	994479.GL877879_gene5027	5.69e-18	90.1	28JCI@1|root,2Z976@2|Bacteria,2GP7M@201174|Actinobacteria,4EA2E@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76455_1	459495.SPLC1_S520210	2.74e-42	157.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_9
k59_60843_1	1565129.JSFF01000005_gene2379	2.16e-84	263.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,2Q8ZN@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	iPC815.YPO3376	Enolase_C,Enolase_N
k59_161414_2	46256.BBIK01000026_gene1849	2.07e-34	131.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,4AWTH@81850|Leuconostocaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	ysdB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_76457_1	1244869.H261_05729	1.62e-77	254.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,2JQ58@204441|Rhodospirillales	204441|Rhodospirillales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_176713_1	323261.Noc_2397	8.42e-69	223.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1WWYU@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_76460_1	1168034.FH5T_19530	1.29e-27	115.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_215510_1	265072.Mfla_0738	1.73e-07	57.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,2KN2F@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_107059_1	1121930.AQXG01000002_gene2403	2.19e-27	109.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1IQ8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_107059_2	458817.Shal_3189	5.66e-29	107.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,2QCB5@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Belongs to the BolA IbaG family	bolA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
k59_192451_1	1165841.SULAR_08864	2.51e-94	277.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42RMF@68525|delta/epsilon subdivisions,2YP6U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_200348_1	46234.ANA_C11804	6.19e-67	237.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_25,PP-binding,Thioesterase
k59_68641_1	472759.Nhal_2290	9.08e-157	462.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1WXXX@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_6766_1	207954.MED92_14028	3.52e-27	108.0	COG0745@1|root,COG0745@2|Bacteria,1MWJG@1224|Proteobacteria,1RPU3@1236|Gammaproteobacteria,1XR8H@135619|Oceanospirillales	135619|Oceanospirillales	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_45339_1	1088868.CIN_13080	8.34e-05	48.9	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_83934_1	1121875.KB907548_gene1206	1.45e-66	214.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1HX45@117743|Flavobacteriia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_115017_1	36874.HQ34_04715	1.15e-23	101.0	COG0545@1|root,COG0545@2|Bacteria,4NP7W@976|Bacteroidetes,2FM5J@200643|Bacteroidia,231KN@171551|Porphyromonadaceae	976|Bacteroidetes	M	peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_146504_1	335541.Swol_2060	4.13e-18	90.5	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia	1239|Firmicutes	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
k59_215525_1	2340.JV46_24170	9.03e-214	599.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1J5A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k59_161431_2	879212.DespoDRAFT_02567	1.43e-92	285.0	COG4006@1|root,COG4006@2|Bacteria,1NYDF@1224|Proteobacteria	1224|Proteobacteria	S	CRISPR-associated protein (Cas_APE2256)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_APE2256
k59_138081_2	177437.HRM2_19280	1.51e-32	121.0	COG3267@1|root,COG3267@2|Bacteria,1Q4DA@1224|Proteobacteria,42YYB@68525|delta/epsilon subdivisions,2WU9J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_238899_1	1168034.FH5T_06485	1.35e-90	289.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NGJJ@976|Bacteroidetes,2FRXF@200643|Bacteroidia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200349_1	395493.BegalDRAFT_1007	1.27e-96	290.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,46075@72273|Thiotrichales	72273|Thiotrichales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k59_138083_1	1168034.FH5T_06895	1.41e-113	333.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,2FPJH@200643|Bacteroidia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_68656_1	1353276.JADR01000002_gene2010	8.8e-36	138.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_53036_1	861299.J421_3718	5.15e-44	152.0	COG3396@1|root,COG3396@2|Bacteria,1ZT9Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_53036_2	109760.SPPG_07026T0	8.44e-28	114.0	COG3186@1|root,KOG3820@2759|Eukaryota,38G6R@33154|Opisthokonta,3NYYK@4751|Fungi	4751|Fungi	E	Biopterin-dependent aromatic amino acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Biopterin_H
k59_169544_1	261292.Nit79A3_3476	6.6e-44	162.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,371TQ@32003|Nitrosomonadales	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_169544_2	1408444.JHYC01000014_gene2318	1.55e-29	120.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1JC9J@118969|Legionellales	118969|Legionellales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_91662_1	1144275.COCOR_00260	3.05e-21	97.4	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_99704_1	85643.Tmz1t_3866	1.61e-38	138.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2VSM1@28216|Betaproteobacteria,2M008@206389|Rhodocyclales	1224|Proteobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_176747_2	1384054.N790_01970	3.51e-46	156.0	COG3917@1|root,COG3917@2|Bacteria,1RJFB@1224|Proteobacteria,1S772@1236|Gammaproteobacteria,1X6G4@135614|Xanthomonadales	135614|Xanthomonadales	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
k59_107080_1	395493.BegalDRAFT_2060	4.43e-96	291.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,4600K@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_138089_1	387093.SUN_1237	5.6e-116	337.0	COG0561@1|root,COG0561@2|Bacteria,1Q5G6@1224|Proteobacteria,42R7D@68525|delta/epsilon subdivisions,2YP2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_169548_1	395493.BegalDRAFT_2017	2.93e-55	184.0	COG0392@1|root,COG0392@2|Bacteria,1PPT2@1224|Proteobacteria,1SS9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
k59_161437_1	1276756.AUEX01000014_gene2953	8.44e-54	171.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,4AE1G@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_161437_2	754476.Q7A_2881	5.84e-82	244.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,46002@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_115029_1	2340.JV46_05960	7.69e-92	296.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
k59_76473_1	204669.Acid345_0550	1.64e-69	223.0	COG1446@1|root,COG1446@2|Bacteria,3Y2YJ@57723|Acidobacteria,2JIZ2@204432|Acidobacteriia	204432|Acidobacteriia	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
k59_122986_1	269799.Gmet_2905	3.74e-100	306.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_215549_1	1049564.TevJSym_ae00930	1.83e-125	364.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4CK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_68671_1	644966.Tmar_2193	5.26e-10	57.4	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_6784_1	1328313.DS2_14534	1.51e-27	118.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465XV@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_53053_1	247634.GPB2148_2838	2.71e-41	143.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0491 Zn-dependent hydrolases, including glyoxylases	blaB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,NUDIX
k59_53053_2	314285.KT71_00075	6.81e-27	108.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1J9GA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_22083_1	883.DvMF_0442	7.13e-07	50.4	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2M81G@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k59_146537_1	1027273.GZ77_10660	2e-11	61.6	COG1943@1|root,COG1943@2|Bacteria,1RC43@1224|Proteobacteria,1S3FI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_153623_1	501479.ACNW01000062_gene2740	1.84e-90	283.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_169574_1	867903.ThesuDRAFT_01105	5.6e-14	76.3	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
k59_107103_1	930169.B5T_03197	4.52e-37	127.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1XK8F@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_107103_2	1385517.N800_10085	9.84e-51	162.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,1X6Y2@135614|Xanthomonadales	135614|Xanthomonadales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_179857_1	1548151.LS70_09600	2.94e-24	93.6	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria	1224|Proteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_179857_2	977880.RALTA_A2067	3.46e-72	231.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,1K0WZ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_203040_1	264732.Moth_1945	6.58e-11	62.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,42EZ9@68295|Thermoanaerobacterales	186801|Clostridia	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_203040_2	313606.M23134_03173	1.23e-25	107.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_48385_1	1122135.KB893151_gene3113	7.98e-109	335.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2U0EN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_133303_1	1517681.HW45_12540	4.02e-33	124.0	COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,1RMJK@1236|Gammaproteobacteria,1XSNP@135623|Vibrionales	135623|Vibrionales	M	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
k59_63789_1	1283300.ATXB01000001_gene1379	9.99e-24	100.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,1XFHT@135618|Methylococcales	135618|Methylococcales	M	PFAM N-acetylneuraminic acid synthase, N-terminal	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
k59_63789_2	1121904.ARBP01000005_gene4705	5.31e-62	201.0	COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,47NJS@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.183,3.2.1.184	ko:K08068,ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
k59_164342_2	525898.Sdel_0392	2.26e-22	99.0	COG2199@1|root,COG3614@1|root,COG3614@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2YMI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,PAS_9
k59_172123_1	504487.JCM19302_2182	4.6e-55	194.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
k59_94840_2	221288.JH992901_gene479	8.01e-32	127.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1JHUP@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
k59_187547_1	4565.Traes_7BS_C08631356.1	7.22e-33	117.0	COG0049@1|root,KOG3291@2759|Eukaryota,37W5M@33090|Viridiplantae,3GKAT@35493|Streptophyta,3M16P@4447|Liliopsida,3IGNB@38820|Poales	2759|Eukaryota	J	Ribosomal protein S7, mitochondrial	RPS7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:1901363	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_125766_1	1452718.JBOY01000137_gene1482	1.45e-23	107.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5067,P22_portal,Pkinase
k59_110206_1	1168034.FH5T_01475	3.74e-73	226.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_40684_1	765910.MARPU_03890	3.94e-36	135.0	COG3203@1|root,COG3203@2|Bacteria,1R49B@1224|Proteobacteria,1RSFN@1236|Gammaproteobacteria,1WWR4@135613|Chromatiales	135613|Chromatiales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40684_2	765914.ThisiDRAFT_0202	1.21e-28	114.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1WXRW@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_86989_1	1094466.KQS_06355	2.9e-05	51.6	COG1752@1|root,COG1752@2|Bacteria,4PIN0@976|Bacteroidetes,1IG40@117743|Flavobacteriia,2NYEB@237|Flavobacterium	976|Bacteroidetes	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_25115_1	1123228.AUIH01000091_gene569	3.18e-52	185.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
k59_141226_1	1123326.JFBL01000001_gene1375	1.36e-13	66.2	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2YPT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_141226_2	1165841.SULAR_06733	1.06e-61	203.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_234177_1	177437.HRM2_25420	7.23e-95	287.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	telA	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_210725_1	102129.Lepto7375DRAFT_7505	2.11e-40	152.0	COG2351@1|root,COG2351@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
k59_17299_1	886293.Sinac_4068	3.09e-73	238.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2IX1D@203682|Planctomycetes	203682|Planctomycetes	H	May be the GTPase, regulating ATP sulfurylase activity	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
k59_2012_1	1123252.ATZF01000003_gene3517	3.59e-16	78.2	COG4589@1|root,COG4589@2|Bacteria,1V05D@1239|Firmicutes,4HDND@91061|Bacilli,27CKS@186824|Thermoactinomycetaceae	91061|Bacilli	S	Cytidylyltransferase family	cdsA3	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_2012_2	1496688.ER33_00560	1.46e-33	122.0	COG0558@1|root,COG0558@2|Bacteria,1GD9W@1117|Cyanobacteria	1117|Cyanobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_234202_1	1165841.SULAR_07148	3.23e-94	281.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2YMER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_234202_2	1165841.SULAR_07153	4.16e-06	47.4	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2YSXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
k59_9812_1	870187.Thini_4345	1.04e-97	293.0	COG1077@1|root,COG1077@2|Bacteria,1PNT2@1224|Proteobacteria	1224|Proteobacteria	D	actin actin family protein	mamK	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_133337_1	223926.28808950	3.74e-15	81.3	COG1345@1|root,COG4412@1|root,COG1345@2|Bacteria,COG4412@2|Bacteria,1RKAD@1224|Proteobacteria,1S8JD@1236|Gammaproteobacteria,1XSHD@135623|Vibrionales	135623|Vibrionales	Q	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
k59_195355_1	1168034.FH5T_04625	3.04e-58	201.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,2FNEV@200643|Bacteroidia	976|Bacteroidetes	M	Phospholipase, patatin family	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k59_164398_1	1165841.SULAR_02918	9e-98	306.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_179896_1	1238182.C882_0307	8.57e-64	225.0	COG0642@1|root,COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JQVJ@204441|Rhodospirillales	204441|Rhodospirillales	T	transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,Response_reg
k59_17313_1	1353276.JADR01000005_gene2411	2.18e-13	72.4	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_2020_1	1179778.PMM47T1_13900	8.33e-47	173.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5067,P22_portal,Pkinase
k59_63803_1	1165841.SULAR_03307	4.88e-70	216.0	COG0500@1|root,COG2226@2|Bacteria,1Q99M@1224|Proteobacteria,43DPI@68525|delta/epsilon subdivisions,2YRRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_125774_1	887898.HMPREF0551_0648	5.3e-42	152.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,1K179@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_79369_1	857087.Metme_2839	3.54e-75	235.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,1XDMJ@135618|Methylococcales	135618|Methylococcales	E	PFAM Aminotransferase, class I	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_79369_2	2340.JV46_27230	9.78e-08	52.4	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1J4Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_102391_1	1206741.BAFX01000103_gene1429	7.64e-07	52.8	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4FU8U@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknJ	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016151,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0032501,GO:0036211,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0046872,GO:0046914,GO:0048871,GO:0050897,GO:0065007,GO:0065008,GO:0071704,GO:0097009,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Peripla_BP_2,Pkinase,PknH_C
k59_110242_1	1250006.JHZZ01000001_gene2646	0.000556	42.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia,3VVBN@52959|Polaribacter	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_234214_1	489825.LYNGBM3L_60080	3.94e-84	253.0	COG0662@1|root,COG0662@2|Bacteria,1GCEU@1117|Cyanobacteria,1HEKR@1150|Oscillatoriales	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_241676_1	861530.ALOZ01000069_gene390	3.78e-53	182.0	COG1062@1|root,COG1062@2|Bacteria,1TP8E@1239|Firmicutes,4HAH9@91061|Bacilli,4GYHQ@90964|Staphylococcaceae	91061|Bacilli	C	Alcohol dehydrogenase GroES-like domain	adhC	-	1.1.1.1,1.1.1.90	ko:K00001,ko:K00055	ko00010,ko00071,ko00350,ko00360,ko00622,ko00623,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00360,map00622,map00623,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00537,M00538	R00623,R00754,R01763,R02124,R02611,R04304,R04805,R04880,R05233,R05234,R05282,R05347,R05348,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_172171_1	714943.Mucpa_3155	8.05e-47	160.0	COG1028@1|root,COG1028@2|Bacteria,4P0BT@976|Bacteroidetes,1IWK3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_164417_1	313596.RB2501_07370	4.26e-77	241.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia	976|Bacteroidetes	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_164417_2	411154.GFO_3344	9.88e-34	119.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1I1AS@117743|Flavobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_156587_1	1165841.SULAR_09684	2.41e-114	333.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2YMKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_2026_1	472759.Nhal_0647	2.64e-20	91.7	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1WW6H@135613|Chromatiales	135613|Chromatiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_87009_1	313596.RB2501_07840	6.21e-108	320.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
k59_110253_1	384765.SIAM614_22772	9.49e-72	231.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2TYKR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	hydrogenase large subunit	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_156590_1	90813.JQMT01000001_gene1595	4.35e-77	256.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,45ZRH@72273|Thiotrichales	72273|Thiotrichales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_164429_2	501479.ACNW01000062_gene2740	2.13e-51	178.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_148801_1	406817.XNC1_2038	5.81e-30	122.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_25136_1	214092.YPO3133	3.55e-82	270.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,41DGC@629|Yersinia	1236|Gammaproteobacteria	U	Efflux pump membrane transporter	acrB	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_17340_1	1207063.P24_09561	4.28e-86	276.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2JQPF@204441|Rhodospirillales	204441|Rhodospirillales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_9831_1	313596.RB2501_05150	5.8e-143	424.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_17342_1	1165841.SULAR_06768	1.37e-126	385.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_17344_1	313596.RB2501_12964	2.23e-09	57.8	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_17344_2	313596.RB2501_12959	4.37e-32	114.0	2E3JI@1|root,32YHX@2|Bacteria,4NUTH@976|Bacteroidetes,1I59V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79391_1	1165841.SULAR_02803	9.09e-26	100.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_87014_1	402881.Plav_0365	1.2e-28	111.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_16345	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_234517_1	1004785.AMBLS11_18845	3.31e-40	149.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	ko:K16076,ko:K18093	ko01501,ko02020,map01501,map02020	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.1.4,1.B.1.1.5,1.B.25.1.1	-	-	OprD,Porin_4
k59_226529_1	690850.Desaf_3621	7.21e-73	244.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_10126_1	223926.28805499	6.09e-84	259.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XTZ8@135623|Vibrionales	135623|Vibrionales	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_211095_1	1026882.MAMP_00044	5.11e-71	224.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,45ZR9@72273|Thiotrichales	72273|Thiotrichales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k59_211095_2	1288298.rosmuc_02142	9.26e-28	108.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria,46NWR@74030|Roseovarius	28211|Alphaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
k59_64152_1	395493.BegalDRAFT_1422	8.71e-76	252.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_211098_1	395493.BegalDRAFT_0562	5.75e-19	86.3	COG0438@1|root,COG0438@2|Bacteria,1MVB4@1224|Proteobacteria,1RNYM@1236|Gammaproteobacteria,4611R@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferases group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_113538_1	1168065.DOK_19160	3.43e-52	176.0	COG3547@1|root,COG3547@2|Bacteria,1RBIF@1224|Proteobacteria,1SDAR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_121603_1	351348.Maqu_4128	1.38e-21	95.5	COG2771@1|root,COG4584@1|root,COG2771@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,46A5W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
k59_82519_1	1122197.ATWI01000012_gene746	1.03e-25	100.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,466UU@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_82519_2	2340.JV46_23830	3.06e-32	117.0	2DMN0@1|root,32SKB@2|Bacteria,1N2XU@1224|Proteobacteria,1T0A7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
k59_105586_1	1165841.SULAR_05113	1.96e-140	402.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2YMPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_74975_1	1111732.AZOD01000004_gene984	3e-33	124.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1X4Z7@135614|Xanthomonadales	135614|Xanthomonadales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_74975_2	414684.RC1_0578	0.000398	43.1	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VAG8@28211|Alphaproteobacteria,2JRZ9@204441|Rhodospirillales	204441|Rhodospirillales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_183313_1	1165841.SULAR_04622	5e-60	192.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_183313_2	1165841.SULAR_04627	2.09e-69	211.0	COG0607@1|root,COG0607@2|Bacteria,1R70B@1224|Proteobacteria,42UX5@68525|delta/epsilon subdivisions,2YPT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_183313_3	929558.SMGD1_1143	4.16e-25	100.0	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,42R2I@68525|delta/epsilon subdivisions,2YP1Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_20471_1	563040.Saut_1309	6.57e-94	291.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_221948_1	313596.RB2501_07360	7.16e-120	349.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1HX72@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_67333_1	243277.VC_0473	5.42e-160	467.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XSX1@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	GO:0003674,GO:0003824,GO:0004802,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_121605_1	1165841.SULAR_08482	4.72e-15	73.9	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_121605_2	1165841.SULAR_08487	2.26e-41	145.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_206324_1	1121459.AQXE01000001_gene2715	2.03e-13	71.2	COG1633@1|root,COG1633@2|Bacteria,1N997@1224|Proteobacteria,42VKE@68525|delta/epsilon subdivisions,2WRKQ@28221|Deltaproteobacteria,2MC42@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_59407_1	1165841.SULAR_06033	5.15e-116	337.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_98191_1	882.DVU_0271	4.74e-19	89.0	COG2204@1|root,COG4192@1|root,COG2204@2|Bacteria,COG4192@2|Bacteria,1R9WW@1224|Proteobacteria,42R68@68525|delta/epsilon subdivisions,2WMSV@28221|Deltaproteobacteria,2M9QN@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_98191_2	1380394.JADL01000004_gene5843	9.22e-13	68.2	COG0745@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,1QWDW@1224|Proteobacteria,2UH6A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_113566_1	1121448.DGI_1686	1.49e-09	62.4	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2M7W6@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3,VWA,VWA_2
k59_145028_1	243090.RB9966	3.2e-62	208.0	COG0535@1|root,COG0535@2|Bacteria,2IX8N@203682|Planctomycetes	203682|Planctomycetes	S	enzyme of the MoaA nifB pqqE family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_145036_1	156889.Mmc1_2481	4.87e-67	223.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2TWW3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
k59_168044_1	1168034.FH5T_02635	7.38e-155	438.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,2FM2X@200643|Bacteroidia	976|Bacteroidetes	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_90242_1	1205753.A989_07697	3.02e-07	51.2	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1X4U3@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k59_90242_2	292415.Tbd_1060	1.71e-35	125.0	2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,2W8F1@28216|Betaproteobacteria,1KT4D@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75006_1	1049564.TevJSym_ak00550	1.77e-20	84.3	COG1918@1|root,COG1918@2|Bacteria,1NBG2@1224|Proteobacteria,1SE39@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Pfam FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_75006_2	631362.Thi970DRAFT_04564	3.52e-70	215.0	COG1553@1|root,COG1553@2|Bacteria,1RJB0@1224|Proteobacteria,1SIZR@1236|Gammaproteobacteria,1WZQ7@135613|Chromatiales	135613|Chromatiales	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_36485_1	555778.Hneap_1445	7.28e-06	49.3	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1X2GE@135613|Chromatiales	135613|Chromatiales	M	Belongs to the skp family	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_129201_1	585543.HMPREF0969_02049	9.32e-45	161.0	COG1231@1|root,COG1231@2|Bacteria,4PMAQ@976|Bacteroidetes,2FQ7W@200643|Bacteroidia,4AVU8@815|Bacteroidaceae	976|Bacteroidetes	E	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
k59_183337_1	1121012.AUKX01000014_gene2771	6.09e-51	171.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia,23FNC@178469|Arenibacter	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_183337_2	1250232.JQNJ01000001_gene2362	1.78e-20	82.4	COG1983@1|root,COG1983@2|Bacteria,4NSQE@976|Bacteroidetes,1I55A@117743|Flavobacteriia	976|Bacteroidetes	KT	PspC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_51637_1	69395.JQLZ01000002_gene1140	1.51e-14	79.3	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,2TSP2@28211|Alphaproteobacteria,2KG7N@204458|Caulobacterales	204458|Caulobacterales	P	TonB-dependent heme hemoglobin receptor family protein	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_198964_1	269799.Gmet_0910	5.77e-16	80.5	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,42VEM@68525|delta/epsilon subdivisions,2WRGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160018_1	1165841.SULAR_00980	1.45e-49	163.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	forD	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	CO_dh,PBP_like_2
k59_168052_1	395493.BegalDRAFT_2503	1.28e-146	440.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,45ZRC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_237484_1	1439940.BAY1663_00855	2.45e-10	58.2	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_237484_2	525904.Tter_0991	1.29e-09	62.4	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria	2|Bacteria	G	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_67349_1	1205908.AKXW01000109_gene1472	1.47e-118	363.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1XUZN@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	3.5.1.81,3.5.1.82	ko:K01461,ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
k59_67351_1	450851.PHZ_c2932	4.55e-27	111.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,2KGAW@204458|Caulobacterales	204458|Caulobacterales	S	PFAM GumN family protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_121628_1	879630.E1A2A8_9CAUD	1.45e-64	220.0	4QHDM@10239|Viruses,4QYV6@35237|dsDNA viruses  no RNA stage,4QRD0@28883|Caudovirales,4QI2W@10662|Myoviridae	10662|Myoviridae	S	Terminase-like family	-	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949	-	-	-	-	-	-	-	-	-	-	-
k59_206337_1	1168034.FH5T_04925	2.32e-11	62.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	fpr	GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004324,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0016043,GO:0016052,GO:0016226,GO:0016491,GO:0016730,GO:0016731,GO:0019318,GO:0019320,GO:0022607,GO:0031163,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901700	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	iECIAI39_1322.ECIAI39_3072,iEcSMS35_1347.EcSMS35_4364,iYL1228.KPN_04002	FAD_binding_6,NAD_binding_1
k59_206337_2	1168034.FH5T_04920	6.13e-125	358.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_75020_1	382245.ASA_1043	3.77e-78	253.0	COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,1RV69@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_29,HTH_Tnp_Mu_2,Mu-transpos_C,rve
k59_28506_1	1049564.TevJSym_ac01310	7.33e-107	322.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1J5IR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_245083_1	1163409.UUA_02186	9.25e-85	270.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,1X4EX@135614|Xanthomonadales	135614|Xanthomonadales	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
k59_183372_1	1173028.ANKO01000112_gene4859	1.71e-10	57.4	2DRDY@1|root,33BC0@2|Bacteria,1G9R7@1117|Cyanobacteria,1HCUI@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
k59_183372_2	373994.Riv7116_5508	1.39e-47	157.0	2BN1K@1|root,32GMS@2|Bacteria,1GKE8@1117|Cyanobacteria,1HT1Y@1161|Nostocales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
k59_75026_1	1165841.SULAR_07375	5.98e-17	73.2	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2YPX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_75026_2	1165841.SULAR_07380	1.34e-89	281.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,42PUG@68525|delta/epsilon subdivisions,2YN09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB-dependent copper receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_44025_1	1165841.SULAR_01973	5.58e-127	365.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_245087_1	391625.PPSIR1_13080	1.1e-72	244.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,438QJ@68525|delta/epsilon subdivisions,2X3XW@28221|Deltaproteobacteria,2YXIE@29|Myxococcales	28221|Deltaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
k59_59429_1	1192034.CAP_1232	4.64e-67	218.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2WNNB@28221|Deltaproteobacteria,2YUAE@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_106070_2	631362.Thi970DRAFT_03838	1.37e-74	234.0	COG2232@1|root,COG2232@2|Bacteria	2|Bacteria	V	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_183822_1	378753.KRH_17510	5.62e-12	65.5	COG0026@1|root,COG0041@1|root,COG0026@2|Bacteria,COG0041@2|Bacteria,2GJCU@201174|Actinobacteria,1W7U7@1268|Micrococcaceae	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_183822_2	2340.JV46_26640	2.65e-97	312.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_44426_1	933262.AXAM01000039_gene1171	2.59e-80	257.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,42NQY@68525|delta/epsilon subdivisions,2WISG@28221|Deltaproteobacteria,2MIXC@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k59_90709_2	289376.THEYE_A1962	1.95e-07	54.7	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria	2|Bacteria	S	AAA domain	gntK	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944	2.7.1.12	ko:K00851,ko:K07028	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_33,APH
k59_183827_1	1165841.SULAR_08242	8.23e-145	427.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_168556_1	1121875.KB907546_gene2212	7.82e-60	198.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,4PFTI@976|Bacteroidetes,1IA7V@117743|Flavobacteriia	976|Bacteroidetes	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
k59_106075_1	1121116.KB894769_gene1329	6.23e-23	95.1	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,4A9YK@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_168557_1	926550.CLDAP_00560	3.32e-87	292.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
k59_214623_1	1307761.L21SP2_2067	1.17e-51	176.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,Mu-transpos_C,rve
k59_82947_1	1500259.JQLD01000016_gene2225	2.35e-75	237.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2U0A4@28211|Alphaproteobacteria,4B7MY@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Cyclopropane fatty acid synthase and related methyltransferases	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_101695_2	335543.Sfum_1614	7.5e-61	202.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MR3A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_132618_1	283942.IL2139	5.95e-25	100.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,2QG8Z@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
k59_94072_1	313603.FB2170_15996	2.81e-59	204.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXSZ@117743|Flavobacteriia,2PH2E@252356|Maribacter	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_39930_1	1165841.SULAR_09439	1.74e-74	223.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,42VNC@68525|delta/epsilon subdivisions,2YQ9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
k59_186804_1	658612.MD26_13715	2.77e-35	130.0	2CABH@1|root,33RHN@2|Bacteria,1NT7G@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_16536_1	326297.Sama_1004	3.13e-144	419.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,2Q9R5@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_163615_1	796620.VIBC2010_13431	2.17e-16	80.5	COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1XYT2@135623|Vibrionales	135623|Vibrionales	S	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
k59_163615_2	1218084.BBJK01000075_gene5239	3.73e-21	94.4	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,2VXDK@28216|Betaproteobacteria,1K5E1@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
k59_140443_1	1236541.BALL01000003_gene543	8.53e-10	58.9	2BU8D@1|root,32PHV@2|Bacteria,1NANB@1224|Proteobacteria,1SFYJ@1236|Gammaproteobacteria,2QCGZ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
k59_140443_2	1123274.KB899417_gene2124	2.23e-05	46.6	COG0745@1|root,COG0745@2|Bacteria,2J86T@203691|Spirochaetes	203691|Spirochaetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_233401_1	1396418.BATQ01000012_gene4451	6.93e-29	115.0	COG1300@1|root,COG1300@2|Bacteria,46SIF@74201|Verrucomicrobia,2IUXK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
k59_233401_2	497964.CfE428DRAFT_2659	2.68e-50	174.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_94082_1	338963.Pcar_2230	1.12e-58	187.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria,43SG8@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	AIR carboxylase	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_101713_1	1168034.FH5T_01590	2.08e-84	260.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,2FYBB@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_101713_2	1168034.FH5T_01585	4.64e-29	110.0	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,2FMT1@200643|Bacteroidia	976|Bacteroidetes	KT	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_155840_2	557598.LHK_00855	8.53e-28	110.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,2KPK6@206351|Neisseriales	206351|Neisseriales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_233403_1	1168034.FH5T_10610	7.25e-98	293.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_171410_1	1034943.BN1094_00290	8.96e-54	194.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1JFDY@118969|Legionellales	118969|Legionellales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	rtxA2_1	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind
k59_32350_2	387093.SUN_0365	1.56e-30	113.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42N4V@68525|delta/epsilon subdivisions,2YN04@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	rluA	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_63032_1	472759.Nhal_2320	7.43e-49	160.0	COG0288@1|root,COG0288@2|Bacteria,1R979@1224|Proteobacteria,1RS85@1236|Gammaproteobacteria,1X075@135613|Chromatiales	135613|Chromatiales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_63032_2	261292.Nit79A3_1856	9.14e-12	62.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_47612_2	1165841.SULAR_00955	7.95e-78	234.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_117274_1	477184.KYC_03902	4.08e-27	115.0	COG3266@1|root,COG3501@1|root,COG3266@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria,3T2DD@506|Alcaligenaceae	28216|Betaproteobacteria	U	protein conserved in bacteria	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
k59_140448_1	502025.Hoch_3156	4.34e-33	124.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148056_1	3656.XP_008460615.1	0.0	1158.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta,4JM10@91835|fabids	35493|Streptophyta	H	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Chromo,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_217861_1	370438.PTH_2123	9.8e-12	64.3	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,2616G@186807|Peptococcaceae	186801|Clostridia	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_217861_2	1122970.AUHC01000030_gene2468	2.04e-15	74.7	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,2V4HA@28211|Alphaproteobacteria,2KBV7@204457|Sphingomonadales	204457|Sphingomonadales	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
k59_47614_1	1189620.AJXL01000065_gene3630	3.52e-47	158.0	COG2335@1|root,COG2335@2|Bacteria,4NVI8@976|Bacteroidetes,1I598@117743|Flavobacteriia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_70706_2	886377.Murru_1268	2.45e-127	372.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia	976|Bacteroidetes	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_240887_1	313596.RB2501_10692	3.32e-89	279.0	COG2936@1|root,COG2936@2|Bacteria,4NHGT@976|Bacteroidetes,1HYGE@117743|Flavobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
k59_55337_1	591158.SSMG_03148	2.81e-43	166.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_63037_1	243233.MCA0072	2.69e-60	194.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1XEER@135618|Methylococcales	135618|Methylococcales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_78522_1	592029.DDD_1384	1.47e-25	107.0	COG4206@1|root,COG4206@2|Bacteria,4NGBJ@976|Bacteroidetes,1HZCD@117743|Flavobacteriia,3HJKZ@363408|Nonlabens	976|Bacteroidetes	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_78522_2	1168034.FH5T_09395	4.14e-61	201.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,2FMVJ@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_202331_1	330214.NIDE2236	3.94e-51	181.0	COG2375@1|root,COG2375@2|Bacteria	2|Bacteria	P	cellular response to nickel ion	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,FAD_binding_9,SIP
k59_202331_2	1215092.PA6_046_00070	8.39e-34	130.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,1RYUN@1236|Gammaproteobacteria,1YHYE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_163646_1	156889.Mmc1_0230	1.13e-35	135.0	COG0639@1|root,COG0639@2|Bacteria,1R5DR@1224|Proteobacteria	1224|Proteobacteria	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_55352_1	1238182.C882_0340	6.57e-109	328.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2JQEC@204441|Rhodospirillales	204441|Rhodospirillales	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_179100_2	1049564.TevJSym_bd00270	1.75e-47	154.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria,1J9YX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_148074_1	1121439.dsat_2222	3.04e-66	209.0	COG1961@1|root,COG1961@2|Bacteria,1RI7A@1224|Proteobacteria,42XNV@68525|delta/epsilon subdivisions,2WSW3@28221|Deltaproteobacteria,2MCEF@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
k59_32617_1	395493.BegalDRAFT_3390	9.33e-17	80.9	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,4609I@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_32617_2	870187.Thini_4345	2.41e-18	82.8	COG1077@1|root,COG1077@2|Bacteria,1PNT2@1224|Proteobacteria	1224|Proteobacteria	D	actin actin family protein	mamK	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_63281_1	1121890.AUDO01000005_gene1553	5.12e-05	47.8	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2NVDD@237|Flavobacterium	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_63281_2	1340493.JNIF01000003_gene1977	1.32e-06	52.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_40222_1	105559.Nwat_0248	1.58e-37	138.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1WWTZ@135613|Chromatiales	135613|Chromatiales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_156068_1	296587.XP_002507372.1	0.000491	50.1	COG5184@1|root,KOG1426@2759|Eukaryota	2759|Eukaryota	DZ	guanyl-nucleotide exchange factor activity	RCCD1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
k59_16786_2	391625.PPSIR1_13855	5.55e-10	61.2	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42UVV@68525|delta/epsilon subdivisions,2WUTB@28221|Deltaproteobacteria,2YUY6@29|Myxococcales	28221|Deltaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_109736_1	1165841.SULAR_02653	2.22e-107	326.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_1491_1	1121937.AUHJ01000007_gene1829	4.34e-112	328.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,1RZDH@1236|Gammaproteobacteria,469MJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_94319_1	1121875.KB907547_gene3446	5.96e-40	147.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
k59_94319_2	1121875.KB907549_gene1749	1.44e-18	81.3	COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,1IINH@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_9337_2	1188252.AJYK01000031_gene1121	3.37e-37	141.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1XSUD@135623|Vibrionales	135623|Vibrionales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_109744_1	1415754.JQMK01000010_gene1376	9.75e-29	119.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,465AY@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_32632_1	1173263.Syn7502_00366	1.47e-44	151.0	COG0377@1|root,COG0377@2|Bacteria,1G04A@1117|Cyanobacteria,1GZ0X@1129|Synechococcus	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhK	-	1.6.5.3	ko:K05582	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ndhK	Oxidored_q6
k59_32632_2	1165841.SULAR_09779	1.79e-18	78.2	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2YPES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the thioredoxin family	trx2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_179433_1	891968.Anamo_1289	2.14e-68	223.0	COG1012@1|root,COG1012@2|Bacteria,3TARM@508458|Synergistetes	508458|Synergistetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.81	ko:K15515	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
k59_78787_1	1123008.KB905693_gene1306	2.35e-27	107.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,2FWW8@200643|Bacteroidia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
k59_233672_2	10228.TriadP23787	0.000845	45.8	KOG1334@1|root,KOG1334@2759|Eukaryota,38CK9@33154|Opisthokonta,3BEGM@33208|Metazoa	33208|Metazoa	S	protein modification by small protein conjugation	DCAF8	GO:0000151,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031461,GO:0031974,GO:0031981,GO:0032991,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0080008,GO:1901564,GO:1902494,GO:1990234	-	ko:K11804	-	-	-	-	ko00000,ko04121	-	-	-	WD40
k59_194804_1	1123399.AQVE01000003_gene2050	2.5e-18	83.6	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,46008@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_194804_2	998674.ATTE01000001_gene4275	1.11e-102	329.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_241157_1	42256.RradSPS_0425	1.35e-66	227.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_151158_1	1173028.ANKO01000065_gene5652	7.32e-41	158.0	COG0531@1|root,COG4191@1|root,COG0531@2|Bacteria,COG4191@2|Bacteria,1G5E0@1117|Cyanobacteria,1HAEY@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_228569_2	1265313.HRUBRA_02570	1.79e-36	134.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1J50W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iSF_1195.SF3294	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_58355_1	580332.Slit_2273	8.35e-31	113.0	2DS8H@1|root,32USH@2|Bacteria,1RCDN@1224|Proteobacteria,2W06A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k59_58355_2	648757.Rvan_2645	2.61e-20	89.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,3N69T@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_236483_1	396588.Tgr7_1308	4.23e-108	318.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,1WXY5@135613|Chromatiales	135613|Chromatiales	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_174396_1	439235.Dalk_4310	3.57e-59	194.0	COG0636@1|root,COG0636@2|Bacteria,1MZ0M@1224|Proteobacteria,42T8K@68525|delta/epsilon subdivisions,2WPRA@28221|Deltaproteobacteria,2MMV3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_C
k59_19507_1	1123242.JH636434_gene3183	5.04e-22	100.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2IYQE@203682|Planctomycetes	203682|Planctomycetes	IQ	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
k59_19508_1	592029.DDD_3211	1.18e-14	70.1	2CWZM@1|root,32T0R@2|Bacteria,4NSUM@976|Bacteroidetes,1I4Q2@117743|Flavobacteriia,3HKPT@363408|Nonlabens	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
k59_19508_2	313596.RB2501_04475	7.65e-68	207.0	COG3651@1|root,COG3651@2|Bacteria,4NQDE@976|Bacteroidetes,1I2UH@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
k59_19508_3	1121875.KB907546_gene2732	3.1e-70	216.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1HX32@117743|Flavobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_4540_1	1026882.MAMP_01487	1.69e-49	167.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,45ZSB@72273|Thiotrichales	72273|Thiotrichales	M	Arabinose 5-phosphate isomerase	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_4540_2	395493.BegalDRAFT_1138	4.18e-88	275.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,45ZXV@72273|Thiotrichales	72273|Thiotrichales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_135801_1	1144305.PMI02_00672	2.52e-49	167.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Esterase,SGL
k59_4542_1	484770.UFO1_0838	3.7e-12	71.2	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4H3ET@909932|Negativicutes	909932|Negativicutes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_159020_1	1245471.PCA10_02720	1.25e-57	189.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1S26N@1236|Gammaproteobacteria,1YKH0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k59_27495_1	694431.DESACE_02240	6.32e-46	159.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria,2M6WV@213113|Desulfurellales	28221|Deltaproteobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k59_135806_1	247639.MGP2080_08861	3.67e-68	220.0	COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,1SVEG@1236|Gammaproteobacteria,1JC1B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
k59_159026_1	1461693.ATO10_11967	3.26e-13	74.7	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,2U473@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
k59_213165_1	1250278.JQNQ01000001_gene3414	7.34e-49	172.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_244077_1	1042163.BRLA_c015020	1.11e-38	146.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,26T6P@186822|Paenibacillaceae	91061|Bacilli	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_135807_2	566466.NOR53_2668	3.59e-49	159.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,1S45S@1236|Gammaproteobacteria,1J9AS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0020037,GO:0030003,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0097577,GO:0098771,GO:1901363	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_112663_1	1245471.PCA10_52980	3.75e-94	284.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1YE85@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_104714_1	1168034.FH5T_09490	3.51e-50	170.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,2FMQV@200643|Bacteroidia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_104714_2	1123325.JHUV01000013_gene1600	3.29e-07	52.4	COG0746@1|root,COG0746@2|Bacteria,2G4CA@200783|Aquificae	200783|Aquificae	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_66200_1	1165841.SULAR_00570	2.58e-45	150.0	2EKI4@1|root,33E83@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128270_1	1168034.FH5T_00235	5.56e-123	361.0	COG0176@1|root,COG0176@2|Bacteria,4P1X0@976|Bacteroidetes,2FX3H@200643|Bacteroidia	976|Bacteroidetes	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_120460_2	1249627.D779_0313	4.51e-82	247.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1WY5Q@135613|Chromatiales	135613|Chromatiales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_120460_3	546274.EIKCOROL_01800	2.21e-37	131.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KR3W@206351|Neisseriales	206351|Neisseriales	S	Macro domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_112666_1	1165841.SULAR_03742	5.79e-83	273.0	COG3387@1|root,COG3387@2|Bacteria,1MXWR@1224|Proteobacteria	1224|Proteobacteria	G	phosphorylase kinase alphabeta	ygeQ	-	-	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_15
k59_19521_1	1384056.N787_05670	5.59e-10	62.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1X394@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
k59_19521_2	709032.Sulku_0647	2.95e-07	53.5	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_213177_1	1121403.AUCV01000054_gene2597	5.19e-12	71.2	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1RCM9@1224|Proteobacteria,42PJE@68525|delta/epsilon subdivisions,2WKQ8@28221|Deltaproteobacteria,2MPRP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg,dCache_2
k59_190006_1	563040.Saut_1310	7.72e-64	216.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_58380_1	1165841.SULAR_00300	2.93e-97	289.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2YP35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	hemK	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_27514_1	4081.Solyc01g007640.2.1	6.33e-32	124.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_244086_1	768671.ThimaDRAFT_3515	3.85e-58	195.0	COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RSQ7@1236|Gammaproteobacteria,1WXN3@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k59_143753_1	498211.CJA_2661	3.1e-32	122.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1FGC1@10|Cellvibrio	1236|Gammaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0421	Glycos_trans_3N,Glycos_transf_3
k59_128694_1	395493.BegalDRAFT_1363	1.24e-57	190.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,460RY@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_12387_1	444860.E3SJ48_9CAUD	5.94e-53	183.0	4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses  no RNA stage,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae	10662|Myoviridae	S	DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159403_1	765912.Thimo_1491	2.08e-43	159.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,1RQRW@1236|Gammaproteobacteria,1WWNC@135613|Chromatiales	135613|Chromatiales	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
k59_174797_1	1165841.SULAR_02653	5.61e-120	358.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_182724_1	1123405.AUMM01000033_gene1830	3.08e-12	67.8	COG3547@1|root,COG3547@2|Bacteria,1TRSB@1239|Firmicutes,4HDPK@91061|Bacilli	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_213679_1	1168034.FH5T_18485	2.03e-93	294.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,2FKYN@200643|Bacteroidia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_205879_2	1168034.FH5T_16650	1.34e-41	143.0	COG1051@1|root,COG1051@2|Bacteria,4NIBP@976|Bacteroidetes,2FNT4@200643|Bacteroidia	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_236917_1	1165841.SULAR_00830	1.57e-97	291.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_120918_1	1430331.EP10_00115	7.73e-46	161.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1WEAR@129337|Geobacillus	91061|Bacilli	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	mtnU	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_159411_1	722419.PH505_ag00130	3.55e-38	143.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,2Q13B@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	(Glycogen) synthase	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008194,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iSFV_1184.SFV_3438	Glyco_transf_5,Glycos_transf_1
k59_19935_1	686340.Metal_1404	1.18e-56	189.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XDTH@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_58798_1	697282.Mettu_2397	3.13e-103	315.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XENG@135618|Methylococcales	135618|Methylococcales	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_12393_1	313596.RB2501_11842	2.1e-77	237.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1HXBH@117743|Flavobacteriia	976|Bacteroidetes	I	Phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
k59_213687_1	1406840.Q763_06015	2.05e-22	97.4	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NSF4@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_213687_2	313595.P700755_003043	7.59e-61	198.0	2DBJ5@1|root,2Z9IG@2|Bacteria,4NI72@976|Bacteroidetes,1I06W@117743|Flavobacteriia,4C4A8@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144186_2	27923.ML120721a-PA	1.34e-48	172.0	COG1816@1|root,KOG1097@2759|Eukaryota,38HSH@33154|Opisthokonta,3BBAE@33208|Metazoa	33208|Metazoa	F	adenosine deaminase	-	-	-	-	-	-	-	-	-	-	-	-	A_deaminase
k59_27928_1	572477.Alvin_1508	1.59e-55	175.0	COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria,1WYQ6@135613|Chromatiales	135613|Chromatiales	P	Part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_27928_2	1121439.dsat_0751	2.04e-23	97.1	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,2M9NY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_190445_1	1000565.METUNv1_03632	4.4e-54	182.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,2KUAS@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_128701_1	485913.Krac_12005	1.95e-89	278.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_27930_1	387093.SUN_0194	8.09e-78	241.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2YTPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_12395_1	349521.HCH_02792	2.64e-41	149.0	COG0436@1|root,COG0436@2|Bacteria,1QG11@1224|Proteobacteria,1SMUT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_205895_1	506534.Rhein_3756	0.000246	50.8	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1WW7V@135613|Chromatiales	135613|Chromatiales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_167428_1	96561.Dole_1509	3.96e-38	135.0	COG1102@1|root,COG1102@2|Bacteria,1R82J@1224|Proteobacteria,42M5Z@68525|delta/epsilon subdivisions,2WMEJ@28221|Deltaproteobacteria,2MI55@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_76382_2	1121012.AUKX01000034_gene640	3.91e-08	58.5	COG1073@1|root,COG1073@2|Bacteria,4NGDK@976|Bacteroidetes,1HX6H@117743|Flavobacteriia,23FT2@178469|Arenibacter	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
k59_52940_1	292415.Tbd_2653	7.2e-19	85.1	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,2VJGQ@28216|Betaproteobacteria,1KSEQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_52940_2	314278.NB231_15218	2.16e-42	148.0	2E08B@1|root,32VW1@2|Bacteria,1N4XX@1224|Proteobacteria,1S67B@1236|Gammaproteobacteria,1X0TY@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_176619_1	1437824.BN940_10176	2.45e-18	90.5	COG5002@1|root,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,2WGQF@28216|Betaproteobacteria,3T9JY@506|Alcaligenaceae	28216|Betaproteobacteria	T	Member of a two-component regulatory system	copS	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_230707_1	1218352.B597_001270	1.18e-38	144.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,1Z04Z@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	HP	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
k59_21969_1	1278309.KB907101_gene627	1e-58	199.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XI2V@135619|Oceanospirillales	135619|Oceanospirillales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_122837_2	472759.Nhal_3802	5.21e-31	121.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1WXCY@135613|Chromatiales	135613|Chromatiales	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_238796_1	1268635.Loa_01510	1.67e-62	211.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1JCH1@118969|Legionellales	118969|Legionellales	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	yfcX	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_238797_1	395493.BegalDRAFT_1676	3.39e-09	57.0	COG3439@1|root,COG3439@2|Bacteria,1NFEI@1224|Proteobacteria,1SCZP@1236|Gammaproteobacteria,463FR@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_238797_2	388399.SSE37_03230	7.79e-19	85.9	COG5501@1|root,COG5501@2|Bacteria,1PB0I@1224|Proteobacteria,2TR7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidation protein SoxZ	MA20_34470	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
k59_169455_1	525244.HMPREF0023_3268	2.26e-60	201.0	COG1502@1|root,COG1502@2|Bacteria,1MXA6@1224|Proteobacteria,1RZZ7@1236|Gammaproteobacteria,3NJBG@468|Moraxellaceae	1236|Gammaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
k59_169455_2	330214.NIDE0413	1.68e-12	68.6	2DQ3Q@1|root,334KX@2|Bacteria	2|Bacteria	S	Proto-chlorophyllide reductase 57 kd subunit	bchB	-	-	-	-	-	-	-	-	-	-	-	PCP_red
k59_130527_1	641524.ADICYQ_2687	1.71e-64	213.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_207679_1	523841.HFX_1588	3.15e-11	71.6	COG3119@1|root,arCOG02785@2157|Archaea,2XV54@28890|Euryarchaeota,23UWR@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_184685_2	203119.Cthe_1107	3.07e-18	87.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WGDE@541000|Ruminococcaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_176634_1	398767.Glov_3574	1.6e-65	209.0	COG1714@1|root,COG1714@2|Bacteria,1N5RK@1224|Proteobacteria,42UX9@68525|delta/epsilon subdivisions,2WQ68@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_76385_1	1168034.FH5T_12580	6.12e-44	158.0	COG2067@1|root,COG2067@2|Bacteria,4NKM1@976|Bacteroidetes,2FPD4@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OMP_b-brl
k59_122857_1	1165841.SULAR_02368	1.69e-66	213.0	COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,42RQH@68525|delta/epsilon subdivisions,2YRCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
k59_184697_1	247634.GPB2148_2794	1.45e-63	204.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,1RQYQ@1236|Gammaproteobacteria,1J5B4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_184697_2	566466.NOR53_177	1.55e-14	71.6	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,1SKH6@1236|Gammaproteobacteria,1J7J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_91602_1	679937.Bcop_0638	6.69e-14	76.6	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,2G2TX@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
k59_6706_1	100226.SCO3450	5.91e-26	105.0	COG1595@1|root,COG1595@2|Bacteria,2GJG2@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_76392_1	1168034.FH5T_16670	1.41e-94	283.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,2FMU4@200643|Bacteroidia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_122859_1	292459.STH1647	2.07e-62	210.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_223336_1	1200792.AKYF01000010_gene2139	3.73e-10	64.7	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_21970_1	1335757.SPICUR_00050	1.1e-09	58.2	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_21970_2	686340.Metal_3962	2.84e-74	236.0	COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,1XDUV@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k59_122863_1	243230.DR_1927	1.05e-54	175.0	COG1943@1|root,COG1943@2|Bacteria,1WMSP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	COGs COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_14138_1	1235794.C811_00853	2e-07	53.1	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CVD3@84998|Coriobacteriia	84998|Coriobacteriia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_14138_2	1552758.NC00_15005	3.33e-55	182.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1X3ZJ@135614|Xanthomonadales	135614|Xanthomonadales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_83871_1	349520.PPE_03685	1.88e-46	155.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,26RHP@186822|Paenibacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_68582_1	1168034.FH5T_07940	9.56e-115	342.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,2FMT8@200643|Bacteroidia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_200253_1	2340.JV46_28180	1.32e-57	186.0	COG5456@1|root,COG5456@2|Bacteria,1MYXM@1224|Proteobacteria,1S6WF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
k59_238808_1	387092.NIS_1827	1.3e-60	206.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	ko:K16076,ko:K18093	ko01501,ko02020,map01501,map02020	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.1.4,1.B.1.1.5,1.B.25.1.1	-	-	OprD,Porin_4
k59_223348_1	1168034.FH5T_15015	7.2e-11	58.5	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,2G0ZE@200643|Bacteroidia	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
k59_153840_2	1165841.SULAR_08627	2.15e-38	132.0	2AKA4@1|root,31B0R@2|Bacteria,1Q6NQ@1224|Proteobacteria,433FV@68525|delta/epsilon subdivisions,2YSK0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45594_1	67352.JODS01000001_gene186	1.43e-22	97.4	COG2183@1|root,COG2183@2|Bacteria,2GKCI@201174|Actinobacteria	201174|Actinobacteria	K	accessory protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_192724_1	948106.AWZT01000064_gene1762	2.53e-22	103.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,2WI28@28216|Betaproteobacteria,1KG96@119060|Burkholderiaceae	28216|Betaproteobacteria	M	hydroxyisourate hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200572_1	2340.JV46_12300	1.91e-155	454.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1J4W7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
k59_22320_1	436308.Nmar_0413	1.02e-20	94.4	COG0674@1|root,arCOG01606@2157|Archaea,41S60@651137|Thaumarchaeota	651137|Thaumarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_161683_1	314275.MADE_1010045	1.72e-09	58.2	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,466DR@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
k59_161683_2	2340.JV46_14640	1.82e-72	220.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1J619@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
k59_215766_1	395493.BegalDRAFT_1798	9.93e-52	177.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,460FI@72273|Thiotrichales	72273|Thiotrichales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
k59_246705_1	314262.MED193_06494	3.5e-36	129.0	COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,2TSU5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
k59_246705_2	314265.R2601_03288	1.27e-56	183.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	kduD	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_153851_1	187272.Mlg_0004	2.03e-85	273.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_184978_1	1165841.SULAR_02543	4.42e-141	408.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_53285_1	1382359.JIAL01000001_gene2059	5.66e-115	342.0	COG1060@1|root,COG1060@2|Bacteria,3Y677@57723|Acidobacteria,2JKTA@204432|Acidobacteriia	204432|Acidobacteriia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_91882_1	2340.JV46_25230	5.72e-41	148.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_91882_2	572477.Alvin_0173	6.46e-45	151.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1WWM4@135613|Chromatiales	135613|Chromatiales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
k59_184981_1	1340493.JNIF01000003_gene2184	2.5e-19	88.2	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
k59_22347_1	1380387.JADM01000009_gene3257	0.000291	44.3	COG3339@1|root,COG3339@2|Bacteria,1N9BI@1224|Proteobacteria,1SC8Z@1236|Gammaproteobacteria,1XQM9@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k59_22347_2	56780.SYN_01406	1.77e-39	135.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42WCF@68525|delta/epsilon subdivisions,2WRES@28221|Deltaproteobacteria,2MQP9@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
k59_208068_1	1051632.TPY_0918	9.37e-17	83.6	COG0654@1|root,COG0654@2|Bacteria,1V6WA@1239|Firmicutes	1239|Firmicutes	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_146820_1	396588.Tgr7_2184	3.33e-58	191.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales	135613|Chromatiales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
k59_215769_1	870187.Thini_0505	1.02e-106	333.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,45ZXY@72273|Thiotrichales	72273|Thiotrichales	K	Tex-like protein N-terminal domain	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_169789_1	7159.AAEL011346-PA	1.13e-08	61.2	COG0737@1|root,KOG4419@2759|Eukaryota,38EWB@33154|Opisthokonta,3B980@33208|Metazoa,3CSMV@33213|Bilateria,41VFG@6656|Arthropoda,3SIHJ@50557|Insecta,451HK@7147|Diptera,45JUF@7148|Nematocera	33208|Metazoa	F	Belongs to the 5'-nucleotidase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0017111	3.1.3.5	ko:K01081,ko:K19970	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko00537,ko01000,ko04090	-	-	-	5_nucleotid_C,Metallophos
k59_91903_1	765910.MARPU_08540	5.99e-67	230.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WX0W@135613|Chromatiales	135613|Chromatiales	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_161700_1	387093.SUN_1787	7.64e-84	251.0	COG0476@1|root,COG0476@2|Bacteria,1P1FY@1224|Proteobacteria,42PK6@68525|delta/epsilon subdivisions,2YNCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_61118_2	1121374.KB891586_gene2464	6.2e-60	197.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478	LpxB
k59_91908_1	1165841.SULAR_08267	1.72e-104	309.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_130866_1	1162668.LFE_0875	1e-78	263.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_61124_1	1211114.ALIP01000012_gene1405	2.48e-61	201.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,1X5H9@135614|Xanthomonadales	135614|Xanthomonadales	S	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_13
k59_115290_1	1168034.FH5T_05385	1.59e-68	211.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_107320_1	1168034.FH5T_04080	8.43e-143	434.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_246713_1	1242864.D187_004215	3.7e-07	58.2	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2YUG9@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
k59_61126_1	1198232.CYCME_1995	5.66e-15	73.9	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,45ZYD@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_61126_2	765912.Thimo_1892	4.09e-21	94.4	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_239159_1	1165841.SULAR_03048	7.25e-152	438.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_208084_1	1246448.ANAZ01000014_gene1487	1.27e-24	101.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4EFV0@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_107322_1	395493.BegalDRAFT_2433	2.62e-23	103.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	iap	-	3.5.1.104,3.5.1.28	ko:K01448,ko:K08307,ko:K19223,ko:K22278	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	CBM50	-	Glyco_hydro_25,LysM,NLPC_P60,Polysacc_deac_1,SH3_3,SLT
k59_192734_1	1134474.O59_004065	2.8e-100	317.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,1FGUJ@10|Cellvibrio	1236|Gammaproteobacteria	KLT	Protein kinase domain	stk1	-	2.7.11.1	ko:K08282,ko:K11916,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,Pkinase
k59_17511_1	56780.SYN_01026	1.53e-21	94.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2MQTG@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k59_17511_2	1268635.Loa_01849	2.04e-20	85.1	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1JEYC@118969|Legionellales	118969|Legionellales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_164677_1	1168034.FH5T_08605	1.22e-79	239.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,2FU39@200643|Bacteroidia	976|Bacteroidetes	S	Acetyltransferase, gnat family	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k59_79569_1	1408433.JHXV01000001_gene763	5.63e-56	186.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1HXVP@117743|Flavobacteriia,2PAYZ@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_87161_1	400682.PAC_15710479	8.94e-06	58.9	29RY4@1|root,2RXCD@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	REJ,Tetraspannin
k59_180165_1	1266925.JHVX01000010_gene1382	4.49e-26	108.0	COG1216@1|root,COG1216@2|Bacteria,1MXMZ@1224|Proteobacteria,2VMGC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_2_3,Glycos_transf_2
k59_210964_1	1267535.KB906767_gene4738	7.06e-05	50.1	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_210964_2	1121105.ATXL01000004_gene1300	0.000786	43.9	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,4B34E@81852|Enterococcaceae	91061|Bacilli	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_79573_1	167542.P9515_00521	6.09e-49	175.0	COG1166@1|root,COG1166@2|Bacteria,1G1C4@1117|Cyanobacteria,1MKZB@1212|Prochloraceae	1117|Cyanobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
k59_203300_1	1304885.AUEY01000036_gene2262	4.56e-60	204.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,2MJ3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_241882_1	387093.SUN_1796	2.45e-153	456.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_203303_1	1165841.SULAR_05573	2.83e-91	287.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_79575_1	1001585.MDS_1870	0.000207	41.6	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,1YFTG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	KT	Response regulator receiver domain	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_79575_2	187272.Mlg_0985	8.63e-70	219.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1WXKN@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_48573_1	398720.MED217_15300	3.75e-52	169.0	COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,1I172@117743|Flavobacteriia,2XIMK@283735|Leeuwenhoekiella	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_210969_1	1182590.BN5_03605	1.88e-05	51.2	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1YHYS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_156810_1	1168034.FH5T_06085	1.32e-95	283.0	COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,2FSUD@200643|Bacteroidia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_187880_1	1248232.BANQ01000015_gene1396	7.49e-15	70.5	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,1XYSR@135623|Vibrionales	135623|Vibrionales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
k59_187880_2	75379.Tint_0080	3.29e-32	121.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,1KK1T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_48582_2	485918.Cpin_3426	1.05e-53	186.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,1IP8X@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_79585_1	1232410.KI421418_gene2364	9.48e-21	93.2	28MC7@1|root,2ZBGF@2|Bacteria,1R7M9@1224|Proteobacteria	1224|Proteobacteria	S	DpnII restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DpnII
k59_79585_2	1282360.ABAC460_16755	5.27e-19	85.5	COG3392@1|root,COG3392@2|Bacteria,1QYMW@1224|Proteobacteria,2U3VQ@28211|Alphaproteobacteria,2KJI9@204458|Caulobacterales	204458|Caulobacterales	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MethyltransfD12
k59_110493_1	1165841.SULAR_03093	2.12e-83	254.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_226423_1	1190606.AJYG01000100_gene994	2.4e-19	85.9	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XT1H@135623|Vibrionales	135623|Vibrionales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_226423_2	2340.JV46_17920	1.86e-18	79.7	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1J6Z2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_195595_1	2340.JV46_18500	4.4e-120	366.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J57P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k59_156823_1	1347392.CCEZ01000049_gene1560	5.21e-23	100.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia,36FNU@31979|Clostridiaceae	186801|Clostridia	E	agmatine deiminase	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
k59_40949_1	1168034.FH5T_11410	2.65e-99	301.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,2FMYJ@200643|Bacteroidia	976|Bacteroidetes	S	RmuC domain protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_126091_1	1165841.SULAR_10549	1.48e-82	256.0	COG0475@1|root,COG0475@2|Bacteria,1RFKE@1224|Proteobacteria,43B2P@68525|delta/epsilon subdivisions,2YT5F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_226768_1	1007103.AFHW01000007_gene4345	2.51e-21	90.1	COG3415@1|root,COG3415@2|Bacteria,1VHWW@1239|Firmicutes,4I7ZS@91061|Bacilli,26YD3@186822|Paenibacillaceae	91061|Bacilli	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_226768_2	102129.Lepto7375DRAFT_0248	3.27e-126	363.0	COG3335@1|root,COG3335@2|Bacteria,1G5W5@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_126459_1	232346.JHQL01000005_gene3238	8.62e-19	91.3	arCOG04928@1|root,2Z880@2|Bacteria,1NBNZ@1224|Proteobacteria,1RQGK@1236|Gammaproteobacteria,1XIHY@135619|Oceanospirillales	135619|Oceanospirillales	S	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
k59_17797_1	1165841.SULAR_10394	1.72e-05	45.1	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2YMJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_17797_2	1165841.SULAR_10409	0.000174	42.7	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2YMZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_172727_1	244581.IM40_04345	2.97e-57	199.0	COG2114@1|root,COG2114@2|Bacteria,1RBTC@1224|Proteobacteria,2TV5V@28211|Alphaproteobacteria,47F19@766|Rickettsiales	766|Rickettsiales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,dCache_1
k59_64427_1	1441629.PCH70_06170	1.75e-18	90.1	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1Z6PM@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_211351_1	1168065.DOK_10682	4.36e-85	270.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1J5D6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-associated, metal-dependent hydrolase	eptA	-	2.7.8.43	ko:K03760,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_118671_1	56107.Cylst_0597	1.59e-24	108.0	COG0642@1|root,COG0784@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1HKT0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_95446_1	1165841.SULAR_01808	1.69e-57	183.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42TAK@68525|delta/epsilon subdivisions,2YPP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_95446_2	1165841.SULAR_01803	9.43e-56	181.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2YP5A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_219200_1	754477.Q7C_126	7.65e-24	91.7	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,462VS@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1244)	-	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
k59_219200_2	558884.JRGM01000149_gene3613	3.67e-10	66.6	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1Y448@135624|Aeromonadales	135624|Aeromonadales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
k59_180593_1	1384056.N787_09330	2.82e-10	66.2	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1X3FJ@135614|Xanthomonadales	135614|Xanthomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_25751_1	1168034.FH5T_20220	2.86e-59	184.0	COG1433@1|root,COG1433@2|Bacteria,4NUWC@976|Bacteroidetes,2FUKC@200643|Bacteroidia	976|Bacteroidetes	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k59_25751_2	385682.AFSL01000085_gene1060	4.83e-08	53.5	COG1149@1|root,COG1149@2|Bacteria,4NJZ1@976|Bacteroidetes,2FSE5@200643|Bacteroidia,3XJ76@558415|Marinilabiliaceae	976|Bacteroidetes	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k59_203693_1	313596.RB2501_05640	1.09e-43	153.0	COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,1HYIN@117743|Flavobacteriia	976|Bacteroidetes	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_180599_1	1122975.AQVC01000012_gene819	1.12e-18	92.4	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2G3E0@200643|Bacteroidia,22WAV@171551|Porphyromonadaceae	976|Bacteroidetes	M	Outer membrane protein, OMP85 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_234805_1	998674.ATTE01000001_gene564	9.48e-57	194.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,1RQ9P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glycos_transf_2,PilZ
k59_157224_1	639282.DEFDS_2114	4.49e-92	291.0	COG0443@1|root,COG0443@2|Bacteria,2GEXS@200930|Deferribacteres	200930|Deferribacteres	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_48883_1	1123399.AQVE01000033_gene1883	1.3e-227	649.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	poly(R)-hydroxyalkanoic acid synthase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
k59_234807_1	2340.JV46_04470	1.03e-115	348.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1J7D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3
k59_180602_1	349521.HCH_06798	2.13e-75	244.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales	135619|Oceanospirillales	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_126471_1	1125863.JAFN01000001_gene1088	5.15e-28	115.0	COG1639@1|root,COG1639@2|Bacteria,1R8H3@1224|Proteobacteria,42PER@68525|delta/epsilon subdivisions,2WP0J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_165141_1	1120956.JHZK01000001_gene3286	3.48e-90	289.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JN4S@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_126474_1	929558.SMGD1_1328	3.05e-71	235.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2YNIK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,dCache_1
k59_219203_1	765912.Thimo_0116	4.41e-37	138.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1WXT8@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_25765_1	395493.BegalDRAFT_1403	2.68e-59	204.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,463KB@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k59_126478_1	1231190.NA8A_09704	2.39e-11	59.7	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,2UAPG@28211|Alphaproteobacteria,43K09@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	MA20_43515	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_126478_2	1279017.AQYJ01000028_gene2022	9.85e-60	189.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,466DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2818 3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_10454_1	563040.Saut_1909	1.83e-134	400.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_87592_1	1239962.C943_03564	4.43e-72	231.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,47XBR@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_226807_1	1165841.SULAR_02663	6.82e-91	281.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_95470_2	1198114.AciX9_0388	1.52e-13	71.6	2EPZB@1|root,33HJW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95470_3	1000565.METUNv1_00218	1.53e-14	70.9	2BN1D@1|root,32GMI@2|Bacteria,1NQ8P@1224|Proteobacteria,2W55E@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82245_1	598659.NAMH_0345	9.85e-64	211.0	COG2340@1|root,COG2340@2|Bacteria,1NAW3@1224|Proteobacteria,42PNS@68525|delta/epsilon subdivisions,2YN4B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
k59_51203_1	598659.NAMH_0970	7.36e-149	437.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_159611_1	118168.MC7420_435	0.000811	41.2	2C5EZ@1|root,32YI6@2|Bacteria,1G9I0@1117|Cyanobacteria,1HD0H@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159611_2	1125699.HMPREF9194_01606	2.07e-18	81.3	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_159611_3	631362.Thi970DRAFT_03240	1.93e-20	84.3	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
k59_167658_1	1120963.KB894496_gene2705	1.7e-25	106.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,2PZIF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_190692_1	886377.Murru_2405	5.01e-25	97.8	COG1595@1|root,COG1595@2|Bacteria,4NFXX@976|Bacteroidetes,1HZT5@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_190692_2	1121012.AUKX01000011_gene2378	5.6e-23	95.1	2BAFY@1|root,323WE@2|Bacteria,4NQ3E@976|Bacteroidetes,1I30F@117743|Flavobacteriia,23HCR@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82249_1	1267535.KB906767_gene2200	3.16e-48	170.0	COG0473@1|root,COG0473@2|Bacteria,3Y3BC@57723|Acidobacteria,2JKC7@204432|Acidobacteriia	204432|Acidobacteriia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_213848_1	1117314.PCIT_10444	1.42e-11	60.1	2DRC8@1|root,33B6W@2|Bacteria,1PAVY@1224|Proteobacteria,1SVUJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213848_2	305900.GV64_00395	1.11e-05	46.2	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XHZW@135619|Oceanospirillales	135619|Oceanospirillales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_144536_1	521719.ATXQ01000005_gene1528	2.63e-27	104.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1YEPB@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3360	YgbB
k59_144536_2	2340.JV46_20990	2.17e-95	283.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1J4T2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7,3.1.26.4	ko:K02342,ko:K14159	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_H,RNase_T
k59_244760_1	243090.RB9109	5.03e-129	393.0	COG0187@1|root,COG0187@2|Bacteria,2IXF8@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_12554_2	760011.Spico_0520	9.76e-42	149.0	COG0571@1|root,COG0571@2|Bacteria,2J6UI@203691|Spirochaetes	203691|Spirochaetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_151825_1	756272.Plabr_3936	2.82e-72	234.0	COG3119@1|root,COG3119@2|Bacteria,2IXIE@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
k59_97796_1	2340.JV46_24740	1.62e-73	232.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_82253_1	392500.Swoo_0810	2.64e-23	98.6	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1RPJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k59_28139_2	344747.PM8797T_29118	8.67e-34	123.0	COG0231@1|root,COG0231@2|Bacteria,2IZ4X@203682|Planctomycetes	203682|Planctomycetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_237192_1	395493.BegalDRAFT_0895	1.36e-87	270.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,460DY@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_74586_1	566466.NOR53_791	6.87e-100	298.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria,1J5BP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_3433	Glyoxalase,Glyoxalase_5
k59_144547_1	1134474.O59_004296	3.8e-36	134.0	2CI9I@1|root,30JUG@2|Bacteria,1P7MP@1224|Proteobacteria,1SUE3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2931)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2931
k59_175395_2	1165841.SULAR_09179	2.26e-171	501.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07648,ko:K07679	ko02020,ko02026,ko05133,map02020,map02026,map05133	M00456,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF_2,HATPase_c,HisKA,Hpt,PAS,Response_reg
k59_105669_1	488538.SAR116_0987	5.32e-32	130.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2U6XU@28211|Alphaproteobacteria,4BR86@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_129268_1	313596.RB2501_11177	2.59e-15	72.8	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_129268_2	1137281.D778_00484	8.13e-37	132.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1I2WA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
k59_129268_3	688270.Celal_0376	1.5e-37	136.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HY87@117743|Flavobacteriia,1F8DA@104264|Cellulophaga	976|Bacteroidetes	E	COGs COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_12993_1	102129.Lepto7375DRAFT_8225	1.45e-29	120.0	COG2114@1|root,COG2114@2|Bacteria,1G11G@1117|Cyanobacteria,1H9NK@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_44064_1	2340.JV46_15900	2.22e-93	292.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1J9M8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PBP_dimer,Transpeptidase
k59_75086_1	216595.PFLU_5213	3.98e-15	82.4	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1YMAE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_206404_1	1165841.SULAR_01828	3.56e-110	329.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_175400_1	1392498.JQLH01000001_gene2545	5.52e-23	100.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1HZ1W@117743|Flavobacteriia,2PHTE@252356|Maribacter	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_51737_1	1121875.KB907549_gene2134	5.67e-10	54.3	2E359@1|root,32Y58@2|Bacteria,4NV78@976|Bacteroidetes,1I50N@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
k59_51737_2	313596.RB2501_01845	2.98e-55	181.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_113648_1	1165841.SULAR_01080	2.62e-57	200.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,42ZJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_206408_1	1165841.SULAR_10684	8.08e-88	270.0	COG3245@1|root,COG3258@1|root,COG3245@2|Bacteria,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,42WAQ@68525|delta/epsilon subdivisions,2YTG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
k59_36583_1	7668.SPU_003319-tr	2.83e-122	398.0	2CMP4@1|root,2QR56@2759|Eukaryota,39VQX@33154|Opisthokonta,3BR69@33208|Metazoa,3E64E@33213|Bilateria	33208|Metazoa	S	Pao retrotransposon peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_129283_1	1232437.KL662007_gene1684	3.05e-20	88.6	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42SSD@68525|delta/epsilon subdivisions,2WPWR@28221|Deltaproteobacteria,2MK6M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_90319_2	313596.RB2501_05620	2.23e-38	130.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I558@117743|Flavobacteriia	976|Bacteroidetes	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_191167_1	519989.ECTPHS_07586	3.97e-133	402.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_5482_1	543632.JOJL01000014_gene9204	1.24e-09	59.3	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D8JC@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_75095_1	867845.KI911784_gene3402	5.72e-07	51.2	COG0013@1|root,COG0013@2|Bacteria,2G6Z3@200795|Chloroflexi,37695@32061|Chloroflexia	32061|Chloroflexia	J	Threonyl alanyl tRNA synthetase SAD	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_5486_1	211165.AJLN01000135_gene5748	1.38e-14	72.0	COG3415@1|root,COG3415@2|Bacteria,1GKFF@1117|Cyanobacteria,1JM31@1189|Stigonemataceae	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_5486_2	472759.Nhal_2930	6.77e-39	136.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,1SZ4J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_82615_1	105559.Nwat_1217	8.04e-28	112.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1X2HE@135613|Chromatiales	135613|Chromatiales	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_152320_1	1335757.SPICUR_01690	1.37e-17	80.9	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1WXC6@135613|Chromatiales	135613|Chromatiales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_152320_2	323261.Noc_3002	1.29e-87	269.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1WWVS@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_237570_1	112098.XP_008608270.1	6.65e-57	191.0	COG0183@1|root,KOG1392@2759|Eukaryota	2759|Eukaryota	I	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	HADHB	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003857,GO:0003988,GO:0004300,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005743,GO:0005759,GO:0005783,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009062,GO:0009295,GO:0009987,GO:0010259,GO:0012505,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016491,GO:0016507,GO:0016508,GO:0016509,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0016829,GO:0016835,GO:0016836,GO:0017076,GO:0019395,GO:0019752,GO:0019866,GO:0019867,GO:0030258,GO:0030554,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0034440,GO:0036094,GO:0036125,GO:0042645,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046395,GO:0048037,GO:0048856,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:0097367,GO:0098588,GO:0098798,GO:0098805,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	2.3.1.16	ko:K07509	ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212	M00085,M00087	R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_229533_2	498211.CJA_0386	1.24e-63	203.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1FGHI@10|Cellvibrio	1236|Gammaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
k59_222072_1	985255.APHJ01000035_gene7	5.97e-52	171.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia,2P6HK@244698|Gillisia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_90337_1	1185652.USDA257_c06580	5.14e-62	214.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,4B92N@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_160088_1	1304275.C41B8_02837	7.16e-23	102.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG3156 Type II secretory pathway component PulK	gspK	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_28601_1	56110.Oscil6304_2854	8.6e-51	184.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1GC4U@1117|Cyanobacteria,1HEM7@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,WD40
k59_90341_2	1335757.SPICUR_07685	2.09e-35	129.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1WWCD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_222075_2	387093.SUN_0068	1.14e-90	276.0	COG2995@1|root,COG2995@2|Bacteria,1PVTB@1224|Proteobacteria,42W6E@68525|delta/epsilon subdivisions,2YQGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
k59_222075_3	387093.SUN_0067	1.56e-45	155.0	COG4246@1|root,COG4246@2|Bacteria,1RENT@1224|Proteobacteria,42SVX@68525|delta/epsilon subdivisions,2YPPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_206416_2	1121342.AUCO01000005_gene169	1.48e-05	52.8	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,24BZ3@186801|Clostridia,36UC4@31979|Clostridiaceae	186801|Clostridia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_90344_2	998674.ATTE01000001_gene515	6.3e-08	55.5	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	General secretion pathway protein I	gspI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
k59_67453_1	644076.SCH4B_0953	2.55e-176	510.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,4NBEB@97050|Ruegeria	28211|Alphaproteobacteria	S	hmm pf01979	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_163210_1	156889.Mmc1_2481	2.08e-63	213.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2TWW3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
k59_124464_1	1380387.JADM01000018_gene3361	2.18e-17	81.6	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1XI82@135619|Oceanospirillales	135619|Oceanospirillales	S	phosphotransferase related to Ser Thr protein	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_240498_1	387093.SUN_1821	9.81e-83	253.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2YMCF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_124467_1	1165841.SULAR_06423	3.43e-70	219.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2YMK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_101324_1	910964.GEAM_2381	9.58e-28	110.0	COG1058@1|root,COG1058@2|Bacteria,1QUB2@1224|Proteobacteria,1RNXG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the CinA family	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_101324_2	1131269.AQVV01000004_gene584	1.12e-47	157.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_163212_1	2340.JV46_17160	6.88e-11	66.6	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1J5M7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_240508_1	1484460.JSWG01000009_gene294	1.03e-13	76.3	COG2982@1|root,COG2982@2|Bacteria,4NHBK@976|Bacteroidetes,1I04H@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_93655_1	240015.ACP_2198	0.00038	48.9	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,HisKA_7TM
k59_147718_1	2340.JV46_28510	7.25e-66	219.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1J5EH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2,HEAT_2
k59_47201_1	283699.D172_0295	2.31e-52	171.0	COG0681@1|root,COG0681@2|Bacteria,1R7Z4@1224|Proteobacteria,1RX6N@1236|Gammaproteobacteria,2Q0CM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_47201_2	981336.F944_00856	0.000211	43.5	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,3NM2Z@468|Moraxellaceae	1236|Gammaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_70341_1	1265505.ATUG01000001_gene4093	3.6e-05	51.2	COG5002@1|root,COG5002@2|Bacteria,1QXTS@1224|Proteobacteria,42QK0@68525|delta/epsilon subdivisions,2WJKM@28221|Deltaproteobacteria,2MKJ9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_101330_1	1121904.ARBP01000006_gene3897	6.62e-76	242.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_240511_1	765914.ThisiDRAFT_1631	5.45e-107	323.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,1WVZB@135613|Chromatiales	135613|Chromatiales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_124479_1	28072.Nos7524_5484	2.24e-24	107.0	COG2304@1|root,COG3209@1|root,COG3210@1|root,COG3266@1|root,COG5276@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG5276@2|Bacteria,1G4UG@1117|Cyanobacteria	1117|Cyanobacteria	M	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
k59_232923_1	566466.NOR53_675	1.76e-37	132.0	COG1416@1|root,COG1416@2|Bacteria,1NP3E@1224|Proteobacteria	1224|Proteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_39461_1	391937.NA2_10458	0.00082	47.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,43HWZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_194109_1	1026882.MAMP_01392	8.22e-35	127.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,460UF@72273|Thiotrichales	72273|Thiotrichales	K	PFAM Response regulator receiver domain	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_16167_1	1165841.SULAR_09239	1.08e-135	388.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42UAY@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE1	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
k59_8512_1	1168034.FH5T_09085	2.25e-57	180.0	COG0614@1|root,COG0614@2|Bacteria,4NRAK@976|Bacteroidetes,2G3C1@200643|Bacteroidia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
k59_116886_1	97139.C824_05798	4.2e-08	59.7	COG0464@1|root,COG0464@2|Bacteria,1TQTZ@1239|Firmicutes,24C5G@186801|Clostridia,36HQS@31979|Clostridiaceae	186801|Clostridia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_124485_1	387093.SUN_2273	3.34e-90	270.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_70353_1	1517681.HW45_09695	4.62e-39	144.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,1XUEX@135623|Vibrionales	135623|Vibrionales	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_8518_1	1192034.CAP_1865	3.34e-22	102.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,43CJE@68525|delta/epsilon subdivisions,2X7TT@28221|Deltaproteobacteria,2Z3N4@29|Myxococcales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_217449_2	306281.AJLK01000052_gene3597	1.8e-13	74.3	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JKD5@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HATPase_c,HisKA,Response_reg
k59_232936_1	1004149.AFOE01000024_gene3235	7.15e-96	294.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,1HY91@117743|Flavobacteriia	976|Bacteroidetes	S	protein related to deoxyribodipyrimidine photolyase	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_93661_1	1165841.SULAR_02833	1.61e-86	258.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,42S7E@68525|delta/epsilon subdivisions,2YP7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	2-keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_101341_2	1349785.BAUG01000003_gene242	2.55e-57	191.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1HWYW@117743|Flavobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_78115_2	1122983.BAJY01000040_gene2191	2.49e-05	51.2	2DPGR@1|root,331ZW@2|Bacteria,4NWFD@976|Bacteroidetes,2FY3H@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF1887)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1887
k59_186434_1	1049564.TevJSym_ac01980	5.52e-77	242.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,1RRKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_225130_1	768671.ThimaDRAFT_2575	4.24e-96	292.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_225130_2	521460.Athe_0600	1.2e-06	52.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V0EJ@1239|Firmicutes,249UV@186801|Clostridia,42H8W@68295|Thermoanaerobacterales	186801|Clostridia	K	helix-turn-helix- domain containing protein, AraC type	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
k59_201895_1	1165841.SULAR_00370	1.46e-20	89.7	COG0790@1|root,COG0790@2|Bacteria,1Q4TH@1224|Proteobacteria,42ZV8@68525|delta/epsilon subdivisions,2YRWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201895_2	1165841.SULAR_00365	9.82e-132	383.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_31819_1	1500890.JQNL01000001_gene656	2.54e-05	45.8	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1X46J@135614|Xanthomonadales	135614|Xanthomonadales	FP	Belongs to the GppA Ppx family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_31819_2	314278.NB231_12074	1.07e-62	214.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales	135613|Chromatiales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_163230_1	313596.RB2501_03760	2.96e-118	368.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IJBA@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_109036_1	265072.Mfla_1580	1.61e-07	51.6	COG2457@1|root,COG2457@2|Bacteria,1RD0V@1224|Proteobacteria,2VS9E@28216|Betaproteobacteria,2KMR7@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF447)	-	-	-	ko:K09154	-	-	-	-	ko00000	-	-	-	DUF447
k59_109036_2	1287116.X734_10530	5.44e-48	172.0	COG1539@1|root,COG1891@1|root,COG2054@1|root,COG1539@2|Bacteria,COG1891@2|Bacteria,COG2054@2|Bacteria,1MY5Q@1224|Proteobacteria,2TRVX@28211|Alphaproteobacteria,43N4B@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	4-HFC-P synthase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	4HFCP_synth,FolB
k59_8527_1	1117379.BABA_21721	9.21e-11	62.8	COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli,1ZFRS@1386|Bacillus	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	yhcS	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
k59_85901_1	869213.JCM21142_72865	9.19e-06	50.8	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,47JQQ@768503|Cytophagia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_47217_1	1380387.JADM01000004_gene2801	1.96e-113	352.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales	135619|Oceanospirillales	L	Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_124496_1	1506583.JQJY01000010_gene1179	1.51e-20	94.4	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia,2NS9E@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Peripla_BP_4,Reg_prop,Response_reg,Y_Y_Y
k59_140138_1	1123267.JONN01000001_gene2355	1.09e-05	48.5	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2JZWJ@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
k59_140138_2	856793.MICA_1161	5.55e-29	113.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2TSAD@28211|Alphaproteobacteria,4BR5B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_209938_3	1283076.M1IDG4_9CAUD	1.88e-101	320.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae	10662|Myoviridae	S	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132527_1	395493.BegalDRAFT_1058	1.08e-58	204.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
k59_147997_1	669502.SSDC_00295	1.17e-24	100.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,1KPSB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_147997_2	395493.BegalDRAFT_3523	4.63e-20	87.8	COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,460BF@72273|Thiotrichales	1236|Gammaproteobacteria	G	PFAM pfkB family carbohydrate kinase	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_39847_2	1122134.KB893650_gene207	1.01e-31	125.0	COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1RYEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_1,Phage_integrase
k59_39855_1	1173024.KI912152_gene425	6.82e-38	143.0	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_117209_1	264730.PSPPH_1911	2.01e-21	99.4	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1Z5YS@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	IQ	AMP-binding enzyme	pvdL	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_233325_1	247634.GPB2148_634	1.61e-57	189.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1J4QB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0281 Malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_24221_1	41431.PCC8801_1977	4.44e-19	86.7	COG3211@1|root,COG3211@2|Bacteria,1G43U@1117|Cyanobacteria,3KH8Y@43988|Cyanothece	1117|Cyanobacteria	Q	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
k59_189747_1	616991.JPOO01000001_gene3292	1.39e-98	290.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia,23FV7@178469|Arenibacter	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_228328_1	395495.Lcho_0471	7.8e-28	105.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,1KM2I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_158769_1	1165841.SULAR_03732	2.35e-89	275.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2YNAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
k59_158769_2	1165841.SULAR_03727	3.21e-45	152.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42RW5@68525|delta/epsilon subdivisions,2YT3G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_236275_1	1408473.JHXO01000006_gene1257	9.33e-69	219.0	COG0657@1|root,COG0657@2|Bacteria,4NGAF@976|Bacteroidetes,2FSWW@200643|Bacteroidia	976|Bacteroidetes	I	Protein of unknown function (DUF1460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460
k59_35185_1	1444309.JAQG01000025_gene3786	1.06e-62	216.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,26TGG@186822|Paenibacillaceae	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_174183_1	1049564.TevJSym_at00740	3.99e-64	201.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,1S2YE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_166743_1	1168034.FH5T_13770	2.59e-41	144.0	COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,2FPNC@200643|Bacteroidia	976|Bacteroidetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
k59_166743_2	1168034.FH5T_13775	3.78e-52	167.0	COG1030@1|root,COG1030@2|Bacteria,4NW09@976|Bacteroidetes,2FRYF@200643|Bacteroidia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
k59_4295_1	1122604.JONR01000023_gene4151	1.18e-49	177.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1X381@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_143510_1	76114.ebA6535	5.91e-33	120.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,2VRXM@28216|Betaproteobacteria,2KYQK@206389|Rhodocyclales	206389|Rhodocyclales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k59_11855_1	1397528.Q671_10600	1.27e-46	163.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XMKX@135619|Oceanospirillales	135619|Oceanospirillales	L	PFAM transposase IS111A IS1328 IS1533, transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_89092_1	396588.Tgr7_0667	1.89e-35	129.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1S9UB@1236|Gammaproteobacteria,1WYVZ@135613|Chromatiales	135613|Chromatiales	M	PFAM Outer membrane lipoprotein Slp	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
k59_189755_1	395493.BegalDRAFT_3133	8.93e-117	347.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_236282_1	694427.Palpr_1655	4.5e-41	144.0	COG2358@1|root,COG2358@2|Bacteria	2|Bacteria	G	TRAP transporter, solute receptor (TAXI family	MA20_27285	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_197698_1	10029.XP_007634688.1	5.42e-74	243.0	COG2036@1|root,COG5262@1|root,KOG1745@2759|Eukaryota,KOG1756@2759|Eukaryota,39ZTV@33154|Opisthokonta,3BPDH@33208|Metazoa,3D6BK@33213|Bilateria,48E1W@7711|Chordata,49B7M@7742|Vertebrata,3JGKY@40674|Mammalia,35PSM@314146|Euarchontoglires,4Q54X@9989|Rodentia	33208|Metazoa	B	Core histone H2A/H2B/H3/H4	HIST3H3	GO:0000228,GO:0000723,GO:0000726,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016233,GO:0022607,GO:0031333,GO:0031490,GO:0031491,GO:0031492,GO:0031497,GO:0031974,GO:0031981,GO:0032200,GO:0032459,GO:0032460,GO:0032991,GO:0032993,GO:0033554,GO:0034622,GO:0034641,GO:0034728,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0044877,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051259,GO:0051262,GO:0051276,GO:0051290,GO:0051291,GO:0051716,GO:0060249,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K11253,ko:K11275	ko05034,ko05202,ko05322,map05034,map05202,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone
k59_182186_1	2340.JV46_19210	3.75e-160	474.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08483,ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_120234_1	1461580.CCAS010000037_gene3098	4.73e-12	67.8	COG2021@1|root,COG2021@2|Bacteria,1V0J9@1239|Firmicutes,4HCZZ@91061|Bacilli,1ZSGS@1386|Bacillus	91061|Bacilli	E	alpha/beta hydrolase fold	estA3	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_120234_2	1122179.KB890480_gene3130	1.19e-55	186.0	COG1052@1|root,COG1052@2|Bacteria,4NIHV@976|Bacteroidetes,1IPKW@117747|Sphingobacteriia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_73659_2	760192.Halhy_1458	5.54e-06	52.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NJX0@976|Bacteroidetes,1J053@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,Y_Y_Y
k59_143515_1	1121957.ATVL01000011_gene3864	1.38e-52	177.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,47KD2@768503|Cytophagia	976|Bacteroidetes	CE	Isocitrate dehydrogenase	-	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_11858_1	886377.Murru_1295	5.29e-47	165.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1HYG5@117743|Flavobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_11858_2	1249997.JHZW01000002_gene1100	1.15e-87	278.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,4PKJ5@976|Bacteroidetes,1HY50@117743|Flavobacteriia,2PH3E@252356|Maribacter	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_89096_1	2340.JV46_29190	7.79e-141	415.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_158782_1	870187.Thini_2501	1.37e-105	324.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,463SM@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_166773_1	234267.Acid_6807	2.97e-27	114.0	COG4584@1|root,COG4584@2|Bacteria,3Y7RI@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_89108_1	1177181.T9A_02435	1.33e-54	177.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XJW7@135619|Oceanospirillales	135619|Oceanospirillales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_89108_2	326297.Sama_1842	2.03e-33	123.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,2Q8RY@267890|Shewanellaceae	1236|Gammaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_158795_1	492774.JQMB01000001_gene5834	1.56e-14	73.9	COG1175@1|root,COG1175@2|Bacteria,1MU84@1224|Proteobacteria,2TRM5@28211|Alphaproteobacteria,4B8GU@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
k59_158795_2	1116375.VEJY3_04145	3.02e-10	61.2	COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,1RRFK@1236|Gammaproteobacteria,1XSZM@135623|Vibrionales	135623|Vibrionales	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
k59_205214_1	72664.XP_006409264.1	9.72e-54	189.0	28Q0M@1|root,2QWP8@2759|Eukaryota,37SGC@33090|Viridiplantae,3G8GC@35493|Streptophyta	35493|Streptophyta	S	Zinc knuckle family protein	-	-	-	-	-	-	-	-	-	-	-	-	MP,RVP,zf-CCHC
k59_19294_1	1185876.BN8_00436	2.2e-41	153.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,47JP7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_205218_1	1165841.SULAR_03103	1.47e-128	380.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_112475_1	351746.Pput_5083	5.06e-44	149.0	COG1943@1|root,COG1943@2|Bacteria,1MZZT@1224|Proteobacteria,1S9JG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_120246_1	1165841.SULAR_10074	3.84e-87	268.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,42M7N@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.10.3.10,1.9.3.1	ko:K02275,ko:K02297	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX2,COX2_TM,COX_ARM,Cytochrom_C,Cytochrome_CBB3
k59_243853_1	1122194.AUHU01000002_gene2742	1.62e-39	148.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_236286_1	1168034.FH5T_05725	1.5e-94	289.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,2FM9G@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_236286_2	1168034.FH5T_05730	5.39e-26	104.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,2FN5Q@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_58115_1	247633.GP2143_09160	2.04e-66	218.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN0I@1236|Gammaproteobacteria,1J9RA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	cusC	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_197711_1	870187.Thini_1860	2.62e-93	291.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,461PI@72273|Thiotrichales	72273|Thiotrichales	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_197711_2	857087.Metme_1250	2.38e-10	62.4	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S3VR@1236|Gammaproteobacteria,1XDX1@135618|Methylococcales	135618|Methylococcales	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
k59_89115_1	2340.JV46_03420	1.6e-95	287.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria,1J5IV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	5'-nucleotidase	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_81549_1	1454004.AW11_01024	7.82e-50	166.0	COG1136@1|root,COG1136@2|Bacteria,1RH0D@1224|Proteobacteria,2VQF4@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	ybbL	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_81549_2	2340.JV46_23920	4.56e-82	248.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1J4MF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_143753_2	2340.JV46_26150	6.55e-67	207.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1J4YR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	pabA	GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135	GATase
k59_27515_1	387093.SUN_1046	7.11e-134	395.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_167030_1	1121878.AUGL01000007_gene1102	3.3e-20	91.7	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_159056_1	387093.SUN_1760	4.32e-162	462.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2YMC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_97183_1	1165841.SULAR_08647	8.57e-109	326.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_12066_1	706587.Desti_1914	1.49e-112	333.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MR3T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_228602_1	1123290.AUDQ01000018_gene987	2.24e-06	54.3	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1UYCB@1239|Firmicutes,4HE6S@91061|Bacilli,26I9A@186818|Planococcaceae	91061|Bacilli	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD
k59_197960_1	626418.bglu_2g09010	1.66e-31	127.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K04780	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_244105_1	1247649.D560_3869	6.21e-59	197.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VIT5@28216|Betaproteobacteria,3T5SV@506|Alcaligenaceae	28216|Betaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_120483_1	1121904.ARBP01000005_gene4823	2.76e-52	176.0	28MAS@1|root,2ZAPE@2|Bacteria,4NJ31@976|Bacteroidetes,47TP8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
k59_4589_2	387093.SUN_2375	8.39e-56	188.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2YRQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_159060_2	1254432.SCE1572_05360	1.71e-28	109.0	COG1309@1|root,COG1309@2|Bacteria,1R59A@1224|Proteobacteria,430YN@68525|delta/epsilon subdivisions,2WVS8@28221|Deltaproteobacteria,2YW07@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_190040_1	1270196.JCKI01000002_gene267	4.56e-35	124.0	2CCSR@1|root,32RWC@2|Bacteria,4NUMI@976|Bacteroidetes,1ITWM@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_4591_1	395493.BegalDRAFT_1848	2.68e-72	226.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,4600U@72273|Thiotrichales	72273|Thiotrichales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_128314_1	472759.Nhal_0438	4.62e-19	86.3	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1WWNF@135613|Chromatiales	135613|Chromatiales	I	Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_143759_1	102107.XP_008223134.1	4.18e-20	90.1	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta,4JN0G@91835|fabids	35493|Streptophyta	L	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3,rve
k59_66221_1	1448139.AI20_02335	1.95e-14	74.3	COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,1S4Z5@1236|Gammaproteobacteria,1Y5ZQ@135624|Aeromonadales	135624|Aeromonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_66221_2	742159.HMPREF0004_2735	2.73e-19	81.3	COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,2VVRR@28216|Betaproteobacteria,3T4QH@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	acyl carrier protein	acpM	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_42999_1	1165841.SULAR_01908	1.18e-33	120.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
k59_174417_1	1123059.KB823013_gene502	6.86e-46	168.0	COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
k59_73947_1	2340.JV46_08130	7.72e-118	352.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1J5DJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_128318_2	1123326.JFBL01000002_gene1767	2.3e-31	120.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_35432_1	395493.BegalDRAFT_2901	1.7e-46	167.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,45ZQF@72273|Thiotrichales	72273|Thiotrichales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_43002_1	7029.ACYPI073888-PA	4.24e-07	57.8	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1758,DUF1759,Peptidase_A17,rve
k59_19528_1	459349.CLOAM0177	2.42e-34	134.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
k59_200804_1	396595.TK90_1952	2.89e-84	262.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_177202_1	1123366.TH3_18410	1.24e-54	184.0	COG2207@1|root,COG2207@2|Bacteria,1RJPK@1224|Proteobacteria,2TVEN@28211|Alphaproteobacteria,2JS94@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
k59_231302_1	90813.JQMT01000001_gene1669	9.75e-205	571.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,463S8@72273|Thiotrichales	72273|Thiotrichales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_84418_1	1056820.KB900643_gene811	5.25e-117	341.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,2PPR1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_107607_1	1165841.SULAR_01465	6.24e-216	605.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2YN1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_7301_1	1121012.AUKX01000021_gene1721	8.42e-97	301.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1HY04@117743|Flavobacteriia,23G80@178469|Arenibacter	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_208357_1	867903.ThesuDRAFT_01406	1.34e-44	159.0	COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,24XXH@186801|Clostridia	186801|Clostridia	C	Cytochrome bd-type quinol oxidase subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_223928_2	386456.JQKN01000017_gene846	2e-21	96.7	COG4832@1|root,arCOG03571@1|root,arCOG03201@2157|Archaea,arCOG03571@2157|Archaea,2Y3NU@28890|Euryarchaeota	28890|Euryarchaeota	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
k59_131101_1	754477.Q7C_1585	1.63e-20	84.3	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_7317_1	762903.Pedsa_2185	6.67e-23	99.4	COG3254@1|root,COG3254@2|Bacteria	2|Bacteria	S	rhamnose metabolic process	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	Beta_helix,rhaM
k59_61362_1	313596.RB2501_06870	2e-66	227.0	COG2373@1|root,COG3209@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SprB
k59_231305_1	1165841.SULAR_06228	1.59e-78	236.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42U2T@68525|delta/epsilon subdivisions,2YPV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_76997_1	616991.JPOO01000003_gene1878	1.49e-72	244.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_246967_2	357809.Cphy_3884	2.26e-17	80.1	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,24H6P@186801|Clostridia,21YQ3@1506553|Lachnoclostridium	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_223939_2	247634.GPB2148_1942	1.91e-05	47.8	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria,1JAKJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_154151_1	1095769.CAHF01000023_gene540	5.34e-39	142.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,2VJMM@28216|Betaproteobacteria,473ZI@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	-	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
k59_216040_1	1121937.AUHJ01000019_gene1302	2.28e-06	48.9	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,464V7@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_92172_1	1260251.SPISAL_07280	9.31e-48	158.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1WYGP@135613|Chromatiales	135613|Chromatiales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_193022_1	1168034.FH5T_18170	5.07e-102	317.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_53546_1	387093.SUN_1075	1.99e-20	93.2	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2YP9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_177240_1	243230.DR_0501	2.09e-12	68.6	COG0167@1|root,COG0167@2|Bacteria,1WI2W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_177240_2	1417296.U879_07500	1.08e-11	64.3	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0694 Thioredoxin-like proteins and domains	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k59_131451_1	1122185.N792_02715	7.56e-51	183.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1X38Z@135614|Xanthomonadales	135614|Xanthomonadales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_247237_1	1298867.AUES01000051_gene4511	6.66e-33	132.0	COG0771@1|root,COG2931@1|root,COG4625@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3K2H3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
k59_224198_1	1168034.FH5T_04715	1.01e-115	350.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,2FMIK@200643|Bacteroidia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_22967_1	1219084.AP014508_gene1188	8.02e-21	93.6	COG1228@1|root,COG1228@2|Bacteria,2GCI8@200918|Thermotogae	200918|Thermotogae	Q	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	-	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1
k59_231578_1	3694.POPTR_0004s19010.1	2.36e-37	143.0	COG2801@1|root,KOG0017@2759|Eukaryota,388WI@33090|Viridiplantae,3GXNG@35493|Streptophyta	3694.POPTR_0004s19010.1|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46192_1	509635.N824_24685	4.44e-44	169.0	COG2972@1|root,COG2972@2|Bacteria,4NJAY@976|Bacteroidetes,1IV7U@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_107938_1	394221.Mmar10_2633	9.72e-08	58.9	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,2U2SA@28211|Alphaproteobacteria,43WX9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_69503_1	457425.XNR_0983	7.67e-40	154.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_84712_1	1238190.AMQY01000021_gene1599	7.29e-68	224.0	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_193253_1	1218075.BAYA01000010_gene3415	8.13e-87	269.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,2VJZI@28216|Betaproteobacteria,1K0UP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_231585_1	378806.STAUR_6857	2.29e-37	145.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2YU9U@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k59_7662_2	305700.B447_11597	1.18e-21	90.1	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2VQQ0@28216|Betaproteobacteria,2KW85@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_154433_1	933262.AXAM01000016_gene177	5.11e-103	328.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria,2MIWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_201158_1	1165841.SULAR_05193	2.16e-109	342.0	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_216325_2	153948.NAL212_1118	2.16e-07	55.5	28MCN@1|root,2ZAQR@2|Bacteria,1N00X@1224|Proteobacteria,2VV0N@28216|Betaproteobacteria,373FE@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_138953_1	641524.ADICYQ_0550	1.04e-34	137.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,47KQH@768503|Cytophagia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_46208_1	396588.Tgr7_2304	3.85e-79	249.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales	135613|Chromatiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_239689_4	13333.ERN04997	1.52e-11	67.0	2CKHQ@1|root,2S5E8@2759|Eukaryota,37WKE@33090|Viridiplantae,3GKNN@35493|Streptophyta	35493|Streptophyta	S	BEST Arabidopsis thaliana protein match is Mitovirus RNA-dependent RNA polymerase (TAIR	-	-	-	-	-	-	-	-	-	-	-	-	Mitovir_RNA_pol
k59_107957_1	755178.Cyan10605_3477	3.68e-20	94.7	COG0517@1|root,COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0517@2|Bacteria,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
k59_22993_1	493475.GARC_0010	5.22e-39	131.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,1S9S2@1236|Gammaproteobacteria,467AI@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k59_22993_2	90814.KL370891_gene521	7.48e-52	164.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S99Z@1236|Gammaproteobacteria,4617I@72273|Thiotrichales	72273|Thiotrichales	S	TIGRFAM toxin-antitoxin system, toxin component, Txe YoeB family	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k59_22994_1	179408.Osc7112_0350	2.44e-07	52.4	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G0AZ@1117|Cyanobacteria,1H7MZ@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_22994_2	179408.Osc7112_0351	1.15e-40	154.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_69524_1	2340.JV46_12710	2.23e-30	120.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1J4Y8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_69524_2	2340.JV46_12700	1.58e-30	117.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1J4PD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_84724_1	1499967.BAYZ01000174_gene5829	4.81e-51	178.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	Thioredoxin_3,URO-D
k59_239694_1	234831.PSM_A1280	2.61e-13	75.9	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,1RFNG@1224|Proteobacteria,1S5JD@1236|Gammaproteobacteria,2Q3DI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_92493_1	1348583.ATLH01000029_gene1339	6.46e-31	120.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia,1F7RW@104264|Cellulophaga	976|Bacteroidetes	C	TIGRFAM Tat (twin-arginine translocation) pathway signal sequence	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_92493_2	616991.JPOO01000001_gene3259	2.53e-155	444.0	COG4654@1|root,COG4654@2|Bacteria,4PMBX@976|Bacteroidetes,1IJR5@117743|Flavobacteriia,23G3P@178469|Arenibacter	976|Bacteroidetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C7
k59_231615_1	1445613.JALM01000079_gene37	4.12e-11	63.5	COG3653@1|root,COG3653@2|Bacteria,2I8X9@201174|Actinobacteria,4E2EA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_231615_2	981384.AEYW01000025_gene4043	8.01e-76	243.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TQWN@28211|Alphaproteobacteria,4NACW@97050|Ruegeria	28211|Alphaproteobacteria	S	Cobalamin biosynthesis protein CobW	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
k59_162272_1	395493.BegalDRAFT_3092	1.05e-115	348.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,460A8@72273|Thiotrichales	72273|Thiotrichales	NU	Secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_84736_1	983544.Lacal_1988	1.62e-08	54.3	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1I18Y@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_84736_2	983548.Krodi_0051	8.6e-62	206.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia,37E2S@326319|Dokdonia	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_172647_1	1165841.SULAR_00265	6.75e-151	427.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2YMPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf04305	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_126334_1	1448857.JFAP01000007_gene468	7.48e-34	123.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2YMH3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_126334_2	1165841.SULAR_00850	1.47e-54	186.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_126344_1	743721.Psesu_1219	1.78e-47	163.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XCJH@135614|Xanthomonadales	135614|Xanthomonadales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_180445_1	641524.ADICYQ_2579	1.67e-08	53.9	2DMNP@1|root,32SQ4@2|Bacteria,4NT2A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_180445_2	1485545.JQLW01000005_gene945	1.61e-47	155.0	COG2402@1|root,COG2402@2|Bacteria,1N28Q@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_110737_1	1165841.SULAR_01210	5.88e-111	335.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42PNH@68525|delta/epsilon subdivisions,2YRFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_33665_2	517418.Ctha_1949	1.04e-91	272.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_126351_1	2340.JV46_08150	3.26e-70	238.0	COG3291@1|root,COG3291@2|Bacteria,1PDUK@1224|Proteobacteria,1S8QS@1236|Gammaproteobacteria,1JBTK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,Peptidase_M43
k59_126351_2	671143.DAMO_0362	6.58e-14	70.1	COG2837@1|root,COG2837@2|Bacteria	2|Bacteria	P	iron assimilation	dyp	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
k59_95353_1	1165841.SULAR_03342	1.76e-79	249.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_95353_2	1165841.SULAR_03347	1.61e-47	157.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_180447_1	1123053.AUDG01000001_gene2329	4.71e-22	108.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WZWS@135613|Chromatiales	135613|Chromatiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
k59_172649_1	1196324.A374_06641	2.14e-27	112.0	2BBM1@1|root,3254X@2|Bacteria,1VRKF@1239|Firmicutes,4HUU7@91061|Bacilli	91061|Bacilli	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_4
k59_41230_1	96561.Dole_0848	2.94e-83	261.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MIZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Starch synthase catalytic	-	-	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176	ko00500,ko01100,ko01110,ko02026,ko04973,map00500,map01100,map01110,map02026,map04973	M00565	R02108,R02112,R02421,R11262	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GH13,GT5	-	Glyco_trans_1_4,Glyco_transf_5,Glycos_transf_1
k59_126352_1	270374.MELB17_22535	6.05e-33	125.0	COG4467@1|root,COG4467@2|Bacteria,1QW8C@1224|Proteobacteria,1S2JX@1236|Gammaproteobacteria,46BUT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_165000_1	377629.TERTU_0591	5.17e-32	131.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria,2PNAV@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_10324_1	1121285.AUFK01000009_gene1215	1.52e-08	60.5	COG2382@1|root,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,1HWW6@117743|Flavobacteriia,3ZQIV@59732|Chryseobacterium	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SASA
k59_242285_1	472759.Nhal_0504	3.59e-24	99.4	COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,1WWFX@135613|Chromatiales	135613|Chromatiales	G	PFAM PfkB domain protein	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB
k59_242285_2	2340.JV46_22230	1.11e-19	83.2	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1SBVN@1236|Gammaproteobacteria,1JBWS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Bacterial DNA-binding protein	hup	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
k59_48812_2	1094563.MCQ_01346	7.18e-13	65.9	COG3561@1|root,COG3561@2|Bacteria,1N1AT@1224|Proteobacteria,2V4YN@28211|Alphaproteobacteria,48TWP@772|Bartonellaceae	28211|Alphaproteobacteria	K	AntA/AntB antirepressor	-	-	-	ko:K07741	-	-	-	-	ko00000	-	-	-	AntA
k59_17715_1	1123008.KB905692_gene234	3.01e-46	160.0	COG1578@1|root,COG1578@2|Bacteria,4NP33@976|Bacteroidetes,2FSGI@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
k59_56566_1	880073.Calab_0069	3.86e-88	273.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acdA	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_165005_1	1123371.ATXH01000007_gene575	2.4e-53	184.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2GHHW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_126368_1	1165841.SULAR_00120	4.19e-129	399.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_149347_1	471854.Dfer_5614	3.86e-32	125.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_110750_2	1249627.D779_3970	8.65e-08	53.9	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,1S2KQ@1236|Gammaproteobacteria,1WY0Z@135613|Chromatiales	135613|Chromatiales	S	PFAM Ankyrin	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
k59_2575_1	1163408.UU9_10859	8.94e-09	54.3	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,1X2Z3@135614|Xanthomonadales	135614|Xanthomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_2575_2	1469245.JFBG01000086_gene1621	8.11e-78	242.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_79862_2	641526.ADIWIN_3752	4.02e-22	92.8	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1HYDH@117743|Flavobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_203599_1	565045.NOR51B_1284	2.22e-28	107.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1J5VG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_188200_1	378806.STAUR_7451	1.03e-16	85.5	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions,2X7C4@28221|Deltaproteobacteria,2Z3F9@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
k59_141709_1	225937.HP15_1349	9.7e-06	52.4	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,4680U@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_95374_1	942016.E9NIH0_9CAUD	4.42e-41	154.0	4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses  no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_180476_1	1168034.FH5T_04975	1.42e-127	366.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_195995_1	1165841.SULAR_08859	7.53e-105	312.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_149360_2	1165841.SULAR_04437	1.51e-75	229.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065	OstA
k59_149360_3	387093.SUN_1223	9.32e-30	110.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2YP3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_48819_1	313596.RB2501_12662	8.05e-113	337.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
k59_110761_1	243090.RB12885	2.41e-12	69.7	COG0564@1|root,COG0564@2|Bacteria,2IXSI@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_141716_1	1219375.CM002139_gene3571	1.48e-18	80.5	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1X6GE@135614|Xanthomonadales	135614|Xanthomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_141716_2	523791.Kkor_2627	4.72e-34	121.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1XK0R@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_211280_1	935567.JAES01000030_gene2864	7.58e-74	233.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1X31Z@135614|Xanthomonadales	135614|Xanthomonadales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_17724_1	1168034.FH5T_05460	1.77e-25	100.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,2FMHD@200643|Bacteroidia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_17724_2	1168034.FH5T_05455	1.55e-37	135.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,2FMNM@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-54 interaction domain protein	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_242310_1	283699.D172_3365	1.04e-14	73.6	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,2PZXB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_234716_1	1278307.KB906975_gene1888	2.33e-57	182.0	COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,2QHY5@267894|Psychromonadaceae	1236|Gammaproteobacteria	J	Elongation factor P (EF-P) OB domain	yeiP	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_33691_1	247634.GPB2148_807	1.32e-103	313.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1J4GP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	GO:0003674,GO:0003824,GO:0004345,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0009117,GO:0009372,GO:0009987,GO:0010699,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0023052,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	e_coli_core.b1852,iAF1260.b1852,iBWG_1329.BWG_1666,iE2348C_1286.E2348C_1977,iEC042_1314.EC042_2019,iECABU_c1320.ECABU_c21130,iECDH10B_1368.ECDH10B_1993,iECDH1ME8569_1439.ECDH1ME8569_1798,iECED1_1282.ECED1_2057,iECIAI39_1322.ECIAI39_1198,iECNA114_1301.ECNA114_1899,iECO26_1355.ECO26_2690,iECP_1309.ECP_1796,iECSF_1327.ECSF_1710,iECUMN_1333.ECUMN_2149,iECW_1372.ECW_m2026,iEKO11_1354.EKO11_1918,iEcDH1_1363.EcDH1_1789,iEcE24377_1341.EcE24377A_2082,iEcHS_1320.EcHS_A1944,iEcSMS35_1347.EcSMS35_1335,iEcolC_1368.EcolC_1780,iG2583_1286.G2583_2304,iJO1366.b1852,iJR904.b1852,iLF82_1304.LF82_3733,iNRG857_1313.NRG857_09280,iSDY_1059.SDY_1138,iWFL_1372.ECW_m2026,iY75_1357.Y75_RS09725,iYL1228.KPN_02367,ic_1306.c2265	G6PD_C,G6PD_N
k59_10364_1	518766.Rmar_2648	5.86e-67	216.0	COG4664@1|root,COG4664@2|Bacteria,4PM5T@976|Bacteroidetes,1FIK6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_157145_2	6412.HelroP66673	6.16e-33	123.0	COG0596@1|root,2QPPY@2759|Eukaryota,38J2J@33154|Opisthokonta,3BHMN@33208|Metazoa,3D5B6@33213|Bilateria	33208|Metazoa	S	Alpha/beta hydrolase family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_196001_1	344747.PM8797T_12006	2.38e-38	141.0	COG4658@1|root,COG4658@2|Bacteria,2IY8E@203682|Planctomycetes	203682|Planctomycetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	-	-	-	-	-	-	-	-	-	-	NQR2_RnfD_RnfE
k59_196001_2	1168034.FH5T_21805	8.3e-52	179.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_180486_1	132113.XP_003494301.1	1.06e-38	142.0	COG0462@1|root,KOG1448@2759|Eukaryota,38CQV@33154|Opisthokonta,3BD0G@33208|Metazoa,3CU7N@33213|Bilateria,41VRM@6656|Arthropoda,3SHV0@50557|Insecta,46HT0@7399|Hymenoptera	33208|Metazoa	EF	N-terminal domain of ribose phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_323,iECBD_1354.ECBD_2414,iECDH1ME8569_1439.ECDH1ME8569_1146,iECNA114_1301.ECNA114_1372,iECW_1372.ECW_m1293,iEcDH1_1363.EcDH1_2440,iEcSMS35_1347.EcSMS35_1935,iNRG857_1313.NRG857_06180,iUMN146_1321.UM146_11025,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,ic_1306.c1665	Pribosyl_synth,Pribosyltran_N
k59_102974_1	1535422.ND16A_3444	2.46e-57	191.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,2Q8CP@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_95384_1	1165841.SULAR_04607	9.15e-46	155.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,42MX3@68525|delta/epsilon subdivisions,2YR64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2951 Membrane-bound lytic murein transglycosylase B	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_95384_2	1165841.SULAR_04612	2.02e-85	268.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GGDEF,PAS_9,dCache_3
k59_56575_2	1112204.GPOL_c12840	6.76e-07	56.2	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4GBZI@85026|Gordoniaceae	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_157149_1	1396141.BATP01000057_gene2938	1.1e-20	91.7	COG1680@1|root,COG1680@2|Bacteria,46T7M@74201|Verrucomicrobia,2IWEF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_64739_1	1240350.AMZE01000092_gene667	6.72e-26	106.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1YUYU@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_219510_1	857087.Metme_0109	4.1e-65	209.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XDQK@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_196394_1	448385.sce8144	1.98e-13	75.5	COG5351@1|root,COG5351@2|Bacteria,1PFNB@1224|Proteobacteria,43A2E@68525|delta/epsilon subdivisions,2X2IJ@28221|Deltaproteobacteria,2YYSV@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2169)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169
k59_126751_1	313596.RB2501_07995	1.97e-45	164.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_173060_1	870187.Thini_2547	5.31e-19	92.8	COG4188@1|root,COG4188@2|Bacteria,1QUVG@1224|Proteobacteria,1T22C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N,PAF-AH_p_II
k59_87873_1	1165841.SULAR_09864	4.27e-112	332.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_87873_2	1165841.SULAR_09869	6.99e-23	95.1	COG1426@1|root,COG1426@2|Bacteria,1QT7G@1224|Proteobacteria,42XGH@68525|delta/epsilon subdivisions,2YQZ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160229_1	1121405.dsmv_1437	2.22e-56	184.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria,2MN2H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	AIR synthase related protein, N-terminal domain	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_136978_1	395493.BegalDRAFT_1156	3.3e-22	90.1	2EEHS@1|root,338BM@2|Bacteria,1NHGX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136978_2	314278.NB231_16068	4.46e-41	142.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1WX1J@135613|Chromatiales	135613|Chromatiales	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_152445_1	351348.Maqu_0997	1.68e-61	207.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,468B0@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_199204_1	518766.Rmar_1049	1.04e-88	271.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1FJ1F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_229720_1	477228.YO5_01304	3.02e-14	66.6	COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,1Z3E2@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	O	COG4736 Cbb3-type cytochrome oxidase, subunit 3	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_229720_2	1149133.ppKF707_3769	7.17e-54	174.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1YEXQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	cytochrome c oxidase, cbb3-type, subunit II	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_136980_1	1121405.dsmv_0420	2.02e-90	293.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria,2MIWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_145262_1	555779.Dthio_PD0734	2.48e-47	154.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
k59_136982_1	412965.COSY_0958	4.09e-08	53.1	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1J5XR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iYL1228.KPN_03664	Biotin_lipoyl
k59_136982_2	443152.MDG893_04644	2.96e-53	172.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,4671T@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0560	DHquinase_II
k59_75283_2	1198232.CYCME_1400	1.31e-17	75.9	2E371@1|root,32Y6T@2|Bacteria,1N8D8@1224|Proteobacteria,1SCAF@1236|Gammaproteobacteria,463E9@72273|Thiotrichales	72273|Thiotrichales	S	YnbE-like lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
k59_75283_3	319225.Plut_1120	2.26e-11	70.1	COG2911@1|root,COG2911@2|Bacteria,1FDFV@1090|Chlorobi	1090|Chlorobi	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
k59_152454_1	314275.MADE_1005825	2.33e-52	179.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_98412_1	1165841.SULAR_07590	7.49e-78	246.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_67617_1	440512.C211_23260	1.01e-89	276.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,1RZTT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	to GP 6723233	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_199215_1	1165841.SULAR_08547	3.82e-110	328.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2YNFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_152460_1	2340.JV46_11270	2.34e-165	465.0	COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1J5KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3412,iSDY_1059.SDY_0027	AdoMet_dc
k59_13150_1	313596.RB2501_10472	4.75e-86	278.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_28737_1	1298593.TOL_1324	1.86e-28	124.0	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,1XMP6@135619|Oceanospirillales	135619|Oceanospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_237701_1	1168034.FH5T_10865	1.23e-36	135.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,2FMMD@200643|Bacteroidia	976|Bacteroidetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_229739_1	1177154.Y5S_02307	2e-49	167.0	COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,1XIXT@135619|Oceanospirillales	135619|Oceanospirillales	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PTPS
k59_44243_1	649638.Trad_0147	1.39e-185	545.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_20865_1	1392488.JHZY01000002_gene1203	4.26e-17	82.8	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,2XJXN@283735|Leeuwenhoekiella	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_5626_1	247634.GPB2148_466	1.49e-100	300.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	protein containing LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_214429_1	1168034.FH5T_02810	1.45e-11	63.9	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,2FWW8@200643|Bacteroidia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
k59_214429_2	1168034.FH5T_02805	2.32e-76	237.0	COG0697@1|root,COG0697@2|Bacteria,4NH9M@976|Bacteroidetes,2FPTW@200643|Bacteroidia	976|Bacteroidetes	EG	membrane	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_121852_1	1165841.SULAR_09154	1.32e-107	317.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2YMCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_59681_1	1168034.FH5T_17760	2.41e-92	293.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,4NF2R@976|Bacteroidetes,2FQYA@200643|Bacteroidia	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
k59_20871_1	472175.EL18_01459	2.78e-13	68.6	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,43HG8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	CoA-binding protein	yccU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k59_20871_2	991905.SL003B_1233	1.89e-42	155.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,4BPHF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_105862_1	395493.BegalDRAFT_1773	5.28e-55	191.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1T16W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
k59_82758_2	1210046.B277_07623	1.19e-16	82.4	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4FGAE@85021|Intrasporangiaceae	201174|Actinobacteria	L	Nudix hydrolase	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_98435_1	391598.FBBAL38_00275	6.08e-77	256.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes,1HYBU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129503_1	643648.Slip_2182	0.000873	45.1	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,25NM7@186801|Clostridia,42K78@68298|Syntrophomonadaceae	186801|Clostridia	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_222279_1	391625.PPSIR1_26758	8.07e-35	137.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YWMT@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_168319_1	1049564.TevJSym_ar00540	4.7e-65	219.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1RQZW@1236|Gammaproteobacteria,1J4RT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_222282_2	667632.KB890199_gene5252	3.81e-31	112.0	COG1426@1|root,COG1426@2|Bacteria,1RD2P@1224|Proteobacteria	1224|Proteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
k59_191319_1	870187.Thini_3823	1.74e-58	198.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,1RS1G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_237710_2	1121405.dsmv_1609	3.19e-37	137.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,42MMZ@68525|delta/epsilon subdivisions,2WJF0@28221|Deltaproteobacteria,2MMM2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_175598_2	1121267.JHZL01000014_gene98	5.04e-30	117.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,42NF9@68525|delta/epsilon subdivisions,2YN85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Cytosine-specific methyltransferase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_145289_1	2340.JV46_22160	2.29e-175	502.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1J4FJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0018995,GO:0022610,GO:0030430,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0050789,GO:0051082,GO:0051704,GO:0061077,GO:0065007,GO:0101031,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_145289_2	2340.JV46_22150	8.32e-55	172.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1J6G0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_129510_1	639030.JHVA01000001_gene3090	2.12e-11	68.9	COG1816@1|root,COG1816@2|Bacteria,3Y2R0@57723|Acidobacteria,2JINF@204432|Acidobacteriia	204432|Acidobacteriia	F	Adenosine/AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k59_152494_1	234267.Acid_1964	5.34e-32	128.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_20892_1	870967.VIS19158_21843	1.93e-68	230.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XUIR@135623|Vibrionales	135623|Vibrionales	L	COG0210 Superfamily I DNA and RNA helicases	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_121863_1	765913.ThidrDRAFT_2298	3.66e-72	231.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1WWE4@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23
k59_129523_1	1131553.JIBI01000001_gene1412	6.42e-49	165.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,2VIYU@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
k59_82770_1	1165841.SULAR_00945	3.6e-117	344.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2YMQ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_229769_1	1165841.SULAR_07800	7.05e-106	317.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,42VG8@68525|delta/epsilon subdivisions,2YR2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
k59_44269_1	926559.JoomaDRAFT_1125	1.17e-32	131.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_191329_1	91464.S7335_177	6.37e-24	102.0	COG1131@1|root,COG1131@2|Bacteria,1G0RY@1117|Cyanobacteria,1H020@1129|Synechococcus	1117|Cyanobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_145298_1	156889.Mmc1_2664	1.22e-31	115.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,2U7MB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_145298_2	1121937.AUHJ01000066_gene16	5.68e-31	119.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,4655T@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_121875_1	1121405.dsmv_3143	0.000339	42.4	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,2MHUD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM oxidoreductase domain protein	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_121875_2	2340.JV46_23710	2.26e-52	167.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1J6H8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
k59_222297_1	870187.Thini_4010	4.54e-94	288.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RMV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
k59_36791_1	1165841.SULAR_06658	4.59e-114	333.0	COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,42ZNV@68525|delta/epsilon subdivisions,2YRNU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_106394_1	1408433.JHXV01000020_gene3536	1.54e-13	75.9	COG3266@1|root,COG3291@1|root,COG5306@1|root,COG3266@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,4NQBS@976|Bacteroidetes,1I3X2@117743|Flavobacteriia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
k59_13606_1	1453505.JASY01000006_gene1224	7.41e-26	107.0	COG4677@1|root,COG4677@2|Bacteria,4PE3Y@976|Bacteroidetes,1IC5K@117743|Flavobacteriia,2NY6G@237|Flavobacterium	976|Bacteroidetes	G	Pectinesterase	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
k59_176129_1	243090.RB4864	2.13e-47	167.0	COG0577@1|root,COG0577@2|Bacteria,2IY8W@203682|Planctomycetes	203682|Planctomycetes	V	Permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_68082_1	313596.RB2501_09605	3.87e-91	288.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_176131_1	502025.Hoch_0071	2.56e-18	85.1	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2YZ1X@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k59_214912_1	246197.MXAN_3002	4.52e-47	172.0	COG0550@1|root,COG0551@1|root,COG0758@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,COG0758@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_21405_1	1123401.JHYQ01000024_gene1266	3.48e-88	270.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,461R6@72273|Thiotrichales	72273|Thiotrichales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_176132_1	313596.RB2501_11657	1.97e-109	339.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HZDJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_168877_1	1123392.AQWL01000003_gene150	1.25e-49	179.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,1KSM8@119069|Hydrogenophilales	119069|Hydrogenophilales	O	HypF finger	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_129951_1	1117315.AHCA01000013_gene3810	1.36e-42	141.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,2Q2QC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	COG1544 Ribosome-associated protein Y (PSrp-1)	yhbH	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_129951_2	999141.GME_03537	4.75e-32	123.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XH8A@135619|Oceanospirillales	135619|Oceanospirillales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_37198_1	1123278.KB893552_gene3706	1.21e-24	103.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47QTY@768503|Cytophagia	976|Bacteroidetes	E	PFAM Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_137447_1	1341151.ASZU01000008_gene1408	3.44e-94	282.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,27AZ9@186824|Thermoactinomycetaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_116576_2	413404.Rmag_0714	1.14e-09	60.5	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1J70K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_85638_1	1165841.SULAR_07173	4.55e-11	62.4	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2YN3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
k59_85638_2	1165841.SULAR_07168	1.3e-78	243.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_186190_1	395493.BegalDRAFT_3161	1.91e-83	259.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,45ZWW@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_139871_2	1304872.JAGC01000003_gene3317	5.95e-09	60.8	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,42UAI@68525|delta/epsilon subdivisions,2WPQ6@28221|Deltaproteobacteria,2M8CN@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k59_519_1	2340.JV46_08240	3.7e-105	313.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1J56G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919	NadA
k59_155265_1	457424.BFAG_03490	3.6e-24	99.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia,4AKN9@815|Bacteroidaceae	976|Bacteroidetes	C	Psort location Cytoplasmic, score 8.96	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_155265_2	1168034.FH5T_04160	6.12e-69	216.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_186194_1	1165841.SULAR_09444	5.14e-17	79.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,42ND2@68525|delta/epsilon subdivisions,2YMQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_2
k59_186194_2	387093.SUN_0388	6.8e-42	145.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2YMRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_224874_1	1165841.SULAR_05898	1.83e-102	325.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_62410_1	555779.Dthio_PD0002	4.89e-24	94.4	COG0358@1|root,COG0358@2|Bacteria,1N8NW@1224|Proteobacteria,42WR7@68525|delta/epsilon subdivisions,2WS70@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Zinc finger, CHC2-type protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
k59_62410_2	767817.Desgi_1675	1.47e-05	49.3	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24BFG@186801|Clostridia,263S2@186807|Peptococcaceae	186801|Clostridia	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_85658_1	688270.Celal_3762	8.58e-08	58.9	COG3291@1|root,COG3291@2|Bacteria,4PHZA@976|Bacteroidetes,1IGQC@117743|Flavobacteriia,1F9WN@104264|Cellulophaga	976|Bacteroidetes	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_108829_1	338963.Pcar_0064	1.9e-05	52.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2X5K8@28221|Deltaproteobacteria,43SE1@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k59_124223_1	1133850.SHJG_1670	2.06e-39	152.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_240317_1	472759.Nhal_1746	3.22e-87	283.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,1WX26@135613|Chromatiales	135613|Chromatiales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_170775_1	1165841.SULAR_08020	1.16e-55	174.0	COG0089@1|root,COG0089@2|Bacteria,1QJHM@1224|Proteobacteria,42TRQ@68525|delta/epsilon subdivisions,2YPUJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_170775_2	1165841.SULAR_08015	7.81e-80	243.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2YN0T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_15966_1	998674.ATTE01000001_gene3987	4.87e-113	334.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,460YT@72273|Thiotrichales	72273|Thiotrichales	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_15966_2	998674.ATTE01000001_gene3986	1.89e-34	126.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	succinylglutamate desuccinylase aspartoacylase	doeB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.125	ko:K15784	ko00260,ko01100,map00260,map01100	-	R09801	RC00064,RC00300	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k59_85661_1	1168034.FH5T_22075	1.46e-63	202.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,2FWWN@200643|Bacteroidia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_224882_2	384765.SIAM614_23372	2.11e-52	184.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2TTSC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional accessory protein	tex	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_62434_1	314278.NB231_12671	3.62e-103	309.0	COG4715@1|root,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
k59_15971_1	1027273.GZ77_22380	2.07e-44	150.0	COG1662@1|root,COG1662@2|Bacteria,1RIVU@1224|Proteobacteria,1SA15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_15971_2	1499967.BAYZ01000134_gene16	2.23e-39	133.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1,HTH_Tnp_IS1,Zn_Tnp_IS1
k59_217234_1	387093.SUN_1841	8.39e-57	183.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2YP4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_232699_1	395493.BegalDRAFT_3528	3.95e-35	127.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,1S32B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_85670_1	313596.RB2501_03030	1.67e-100	300.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
k59_541_1	2340.JV46_16620	1.75e-59	196.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SBMS@1236|Gammaproteobacteria,1JBHM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_101118_1	237368.SCABRO_01719	6.66e-61	191.0	COG1943@1|root,COG1943@2|Bacteria,2J3NS@203682|Planctomycetes	2|Bacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_124230_1	1121035.AUCH01000007_gene522	8.05e-109	333.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria,2KV2Z@206389|Rhodocyclales	206389|Rhodocyclales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_178543_1	1278307.KB906990_gene3107	5.28e-18	81.6	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,2QITP@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Patatin-like phospholipase	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_178543_2	563040.Saut_0794	6.29e-18	82.0	2AJGA@1|root,31A2S@2|Bacteria,1Q4T9@1224|Proteobacteria,42ZUF@68525|delta/epsilon subdivisions,2YRSU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_217248_1	1390370.O203_13020	3.07e-29	111.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1YD65@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH
k59_217248_2	935567.JAES01000007_gene1895	1.66e-54	179.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1X2XZ@135614|Xanthomonadales	135614|Xanthomonadales	S	Serine hydrolase involved in the detoxification of formaldehyde	fghA	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
k59_162965_2	880072.Desac_2397	2.52e-24	102.0	COG3359@1|root,COG3359@2|Bacteria,1R6A2@1224|Proteobacteria,42MVN@68525|delta/epsilon subdivisions,2WK0C@28221|Deltaproteobacteria,2MR5S@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
k59_155298_1	768671.ThimaDRAFT_2574	1.08e-84	264.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WW4B@135613|Chromatiales	135613|Chromatiales	T	response regulator	glnG	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_31620_1	1165841.SULAR_08739	1.71e-199	556.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2YMA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_54755_1	313628.LNTAR_17118	1.88e-113	340.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_240327_1	903818.KI912269_gene50	1.61e-13	75.5	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria	57723|Acidobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_70117_1	1168034.FH5T_11715	8.68e-111	330.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FP4D@200643|Bacteroidia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_155304_1	502025.Hoch_4833	3.18e-09	57.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,42YBQ@68525|delta/epsilon subdivisions,2WTKK@28221|Deltaproteobacteria,2Z06Q@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_155304_2	670487.Ocepr_1867	2.36e-66	208.0	COG4665@1|root,COG4665@2|Bacteria,1WJCH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	TRAP-type mannitol chloroaromatic compound transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_85681_1	1340493.JNIF01000003_gene4366	2.57e-52	176.0	COG0345@1|root,COG0345@2|Bacteria,3Y41B@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_147506_1	1347342.BN863_31590	2.79e-81	255.0	COG2367@1|root,COG2367@2|Bacteria,4NHF9@976|Bacteroidetes,1HZHM@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
k59_147507_2	1168034.FH5T_03155	1.07e-53	179.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,2FP3H@200643|Bacteroidia	976|Bacteroidetes	T	ATPase related to phosphate starvation-inducible protein PhoH	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_124240_1	90814.KL370891_gene740	1.4e-78	261.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,45ZVJ@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_193916_1	329726.AM1_3454	1.56e-48	177.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG2202@1|root,COG3290@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria,1GHDM@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF,HATPase_c,HisKA_2,PAS_3,PAS_4,PAS_9
k59_15982_1	1052684.PPM_1307	1.89e-33	120.0	2EF06@1|root,338T9@2|Bacteria,1TZ3V@1239|Firmicutes,4I8AW@91061|Bacilli,26ZFR@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162988_1	196367.JNFG01000020_gene4594	4.04e-39	147.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,2VK41@28216|Betaproteobacteria,1K1NJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
k59_124882_1	502025.Hoch_2359	9.88e-104	329.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_78531_2	272559.BF9343_3996	2.97e-29	112.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,2FMKB@200643|Bacteroidia,4ANGK@815|Bacteroidaceae	976|Bacteroidetes	K	LytTr DNA-binding domain protein	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_101741_1	543632.JOJL01000002_gene8102	1.88e-06	56.6	COG1032@1|root,COG1032@2|Bacteria,2HWUC@201174|Actinobacteria,4DKD5@85008|Micromonosporales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_39964_1	313603.FB2170_15996	8.44e-42	153.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXSZ@117743|Flavobacteriia,2PH2E@252356|Maribacter	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_39964_2	929562.Emtol_0993	1.32e-11	63.5	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,47JAR@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_179115_1	56780.SYN_00125	2.09e-102	305.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MQ3Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	PFAM Type II IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_39969_1	1541065.JRFE01000011_gene4574	8.99e-46	162.0	COG3385@1|root,COG3385@2|Bacteria,1G2NV@1117|Cyanobacteria,3VMET@52604|Pleurocapsales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1,DDE_Tnp_2
k59_39969_2	879212.DespoDRAFT_02660	3.84e-56	189.0	COG3385@1|root,COG3385@2|Bacteria,1NNH0@1224|Proteobacteria	1224|Proteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_16576_1	314278.NB231_15223	3.45e-91	295.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_32375_1	1168034.FH5T_09255	9.9e-17	78.2	28IWX@1|root,2Z8V0@2|Bacteria,4PPT4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_32375_2	1168034.FH5T_09260	1.32e-56	186.0	COG2897@1|root,COG2897@2|Bacteria,4NKP3@976|Bacteroidetes	976|Bacteroidetes	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_109493_1	1267535.KB906767_gene3655	9.01e-38	136.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_124909_1	1168034.FH5T_08820	1.73e-49	170.0	COG0745@1|root,COG0745@2|Bacteria,4PM6N@976|Bacteroidetes,2G0CY@200643|Bacteroidia	976|Bacteroidetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
k59_39975_2	314230.DSM3645_28137	3.56e-18	81.3	COG3436@1|root,COG3436@2|Bacteria,2J11P@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_70717_1	870187.Thini_1154	2.37e-59	191.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,462SM@72273|Thiotrichales	72273|Thiotrichales	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
k59_70717_2	247634.GPB2148_3579	1.88e-23	95.9	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1J56X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_132665_1	1123228.AUIH01000001_gene1294	1.98e-54	177.0	COG1225@1|root,COG1225@2|Bacteria,1NBR9@1224|Proteobacteria,1SDMZ@1236|Gammaproteobacteria,1XQQH@135619|Oceanospirillales	135619|Oceanospirillales	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_124911_1	236814.IX39_00265	1.23e-40	154.0	COG0642@1|root,COG2203@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia,3ZQ9R@59732|Chryseobacterium	976|Bacteroidetes	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_147037_1	1165841.SULAR_09854	1.9e-48	157.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2YPE3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_77412_1	2340.JV46_10370	1.01e-111	335.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1J5MK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0498 Threonine synthase	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
k59_7774_1	933262.AXAM01000025_gene3415	6.99e-56	189.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_92917_1	1168034.FH5T_12085	2.83e-66	212.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,2FM8A@200643|Bacteroidia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_23240_1	643562.Daes_0814	9.52e-33	123.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2WJ24@28221|Deltaproteobacteria,2M83H@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_23240_2	984892.SPSE_1339	2.65e-13	70.1	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,4GXSF@90964|Staphylococcaceae	91061|Bacilli	J	asparaginyl-tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_162524_1	1168034.FH5T_01025	7.7e-69	222.0	COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes	976|Bacteroidetes	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_N
k59_100644_1	1168034.FH5T_20490	1.86e-54	188.0	COG1629@1|root,COG4771@2|Bacteria,4PKB3@976|Bacteroidetes	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
k59_201218_1	2340.JV46_11320	2.65e-139	402.0	COG1638@1|root,COG1638@2|Bacteria,1PG0D@1224|Proteobacteria	1224|Proteobacteria	G	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_61985_1	335543.Sfum_0929	4.84e-66	226.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_69668_1	313596.RB2501_03175	5.86e-122	371.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_224451_1	1121935.AQXX01000110_gene5464	4.36e-47	172.0	COG2373@1|root,COG3755@1|root,COG2373@2|Bacteria,COG3755@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,LprI,MG1
k59_178008_1	879212.DespoDRAFT_01215	1.16e-61	201.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_38741_1	398720.MED217_01340	2.97e-75	237.0	COG0627@1|root,COG0627@2|Bacteria,4PMM8@976|Bacteroidetes,1IJXF@117743|Flavobacteriia,2XINH@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
k59_123834_1	1185876.BN8_01163	1.6e-16	84.3	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,47PB5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_31074_1	765912.Thimo_2212	7.31e-94	292.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1WXXQ@135613|Chromatiales	135613|Chromatiales	G	Alpha amylase catalytic	-	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	-
k59_139392_1	283699.D172_1047	1.87e-05	48.9	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,2Q0WE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_139392_2	1137799.GZ78_26205	3.39e-28	108.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_154814_1	616991.JPOO01000001_gene4473	6.12e-69	211.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_31075_1	240015.ACP_0277	8.07e-18	82.0	COG1692@1|root,COG1692@2|Bacteria,3Y3YJ@57723|Acidobacteria,2JIAY@204432|Acidobacteriia	204432|Acidobacteriia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_31075_2	313628.LNTAR_08281	3.28e-26	108.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_232170_1	1165841.SULAR_07955	2.91e-119	341.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2YMUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_116103_1	1304284.L21TH_0439	2.98e-16	86.3	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,36UN0@31979|Clostridiaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_178022_2	1165841.SULAR_05268	5.93e-134	386.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_85154_1	768671.ThimaDRAFT_1752	9.01e-95	293.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
k59_154819_1	373994.Riv7116_2981	1.52e-37	145.0	COG1413@1|root,COG4249@1|root,COG5635@1|root,COG1413@2|Bacteria,COG4249@2|Bacteria,COG5635@2|Bacteria,1G233@1117|Cyanobacteria,1HJ1W@1161|Nostocales	1117|Cyanobacteria	CT	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14
k59_208965_1	1165841.SULAR_08147	1.5e-81	245.0	2CJ51@1|root,32S98@2|Bacteria,1N0AX@1224|Proteobacteria,42U46@68525|delta/epsilon subdivisions,2YPVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
k59_208965_2	1165841.SULAR_08142	1.44e-151	440.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,42MWP@68525|delta/epsilon subdivisions,2YNEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_15532_1	489825.LYNGBM3L_26490	6.73e-07	60.1	COG1672@1|root,COG4928@1|root,COG1672@2|Bacteria,COG4928@2|Bacteria,1G1HK@1117|Cyanobacteria	2|Bacteria	T	PFAM KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,KAP_NTPase,Peripla_BP_6,TPR_19
k59_38996_1	983548.Krodi_2089	8.38e-50	167.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia,37ENA@326319|Dokdonia	976|Bacteroidetes	H	Pterin binding enzyme	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_232464_2	1234409.C683_1240	7.06e-07	54.7	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,4AZGX@81852|Enterococcaceae	91061|Bacilli	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_31457_1	1079460.ATTQ01000014_gene2897	3.91e-09	63.5	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BCPC@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_2,TPR_8
k59_201495_1	1335757.SPICUR_07955	1.97e-39	148.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1WWAT@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_376_1	348780.NP_0212A	9.41e-06	54.3	COG1061@1|root,arCOG00874@2157|Archaea,2XTYQ@28890|Euryarchaeota,23SWE@183963|Halobacteria	183963|Halobacteria	K	COG1061 DNA or RNA helicases of superfamily II	rad25	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,ResIII
k59_93289_1	1188256.BASI01000001_gene926	4.59e-67	222.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2U4S4@28211|Alphaproteobacteria,3FDJN@34008|Rhodovulum	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_240173_1	553385.JEMF01000036_gene1114	8.67e-12	69.7	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XH3K@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_162772_2	351348.Maqu_3168	5.18e-68	223.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,465J7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_178340_1	1121931.AUHG01000016_gene1001	1.59e-20	95.1	COG2271@1|root,COG2271@2|Bacteria,4NK2M@976|Bacteroidetes,1I107@117743|Flavobacteriia	976|Bacteroidetes	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_224716_1	517418.Ctha_0501	8.32e-50	163.0	COG0229@1|root,COG0229@2|Bacteria,1FDWG@1090|Chlorobi	1090|Chlorobi	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_232485_1	1114970.PSF113_3495	4.7e-24	105.0	COG3437@1|root,COG4191@1|root,COG5002@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	todS_19	-	2.7.13.3	ko:K11527,ko:K17292,ko:K19616	ko02020,map02020	M00771	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko04147,ko04812	-	-	-	HATPase_c,HTH_18,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y,dCache_1
k59_62245_1	1168034.FH5T_08385	7.23e-81	261.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_147312_1	640081.Dsui_0894	2.58e-67	233.0	COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVRJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,Response_reg
k59_170617_1	1453503.AU05_20090	5.81e-33	125.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1YF5A@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_8153_1	1165841.SULAR_08789	2.83e-110	322.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2YMUY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_8153_2	1165841.SULAR_08794	6.03e-35	119.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria	1224|Proteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_8153_3	317025.Tcr_0147	2.56e-17	80.1	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,1RPIZ@1236|Gammaproteobacteria,460KR@72273|Thiotrichales	72273|Thiotrichales	E	PFAM FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_108698_1	1295642.H839_18145	1.17e-53	189.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1WF6K@129337|Geobacillus	91061|Bacilli	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_224721_1	1168034.FH5T_05815	1.21e-90	281.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,2FQ2M@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase, M28 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_217042_1	2340.JV46_09620	1.94e-163	462.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1J9U3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	glxR	GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.1.1.411,1.1.1.60	ko:K00042,ko:K08319	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_139707_1	935557.ATYB01000010_gene7	3.67e-09	63.2	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,4BIRP@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_162778_1	2340.JV46_15240	4.2e-44	148.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1J5R2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
k59_240178_1	248742.XP_005644087.1	6.28e-09	58.9	COG1179@1|root,KOG2018@2759|Eukaryota,37KU5@33090|Viridiplantae,34JCC@3041|Chlorophyta	3041|Chlorophyta	O	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k59_240178_2	630626.EBL_c33720	1.13e-13	72.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Deoxyribonuclease	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_108701_1	1165841.SULAR_07470	4.88e-19	85.5	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_108701_2	367737.Abu_2134	1.5e-29	112.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2YNW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_186047_2	1244528.CFT03427_1255	6.9e-29	110.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2YPAE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	hmm pf03061	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
k59_131907_1	382464.ABSI01000012_gene2198	3.21e-16	79.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
k59_131907_2	1123393.KB891326_gene28	2.04e-19	85.5	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VHTZ@28216|Betaproteobacteria,1KS7H@119069|Hydrogenophilales	119069|Hydrogenophilales	KT	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind,Peptidase_S24
k59_162790_1	1232683.ADIMK_2473	3.27e-68	212.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,4643W@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186	Pribosyltran
k59_147313_1	1165841.SULAR_06018	4.18e-197	560.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_147313_2	1165841.SULAR_06013	1.63e-89	263.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,42ST2@68525|delta/epsilon subdivisions,2YPG7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_124050_2	1232683.ADIMK_4184	1.72e-75	247.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,466PE@72275|Alteromonadaceae	1236|Gammaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,Pkinase
k59_209268_1	1117647.M5M_05170	9.63e-51	164.0	COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,1J731@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3,Glutaredoxin
k59_143043_1	642227.HA49_14190	7.77e-27	112.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,1RS1C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	GNAT family acetyltransferase	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	ATP-grasp_5,CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK
k59_143046_1	1165841.SULAR_04387	6.73e-96	289.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_65497_1	387093.SUN_0193	1.49e-125	381.0	COG4166@1|root,COG4166@2|Bacteria,1Q4KZ@1224|Proteobacteria,43A0X@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_143052_1	392499.Swit_1375	6.73e-58	191.0	COG2207@1|root,COG2207@2|Bacteria,1MY46@1224|Proteobacteria,2TUHY@28211|Alphaproteobacteria,2K3DM@204457|Sphingomonadales	204457|Sphingomonadales	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
k59_11420_1	1292035.H476_3622	3.79e-11	70.5	COG5527@1|root,COG5527@2|Bacteria,1W658@1239|Firmicutes	2|Bacteria	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
k59_135145_1	1122134.KB893651_gene2404	1.47e-40	143.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1XIA9@135619|Oceanospirillales	135619|Oceanospirillales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_158363_1	1165841.SULAR_03098	4.71e-255	713.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_197248_1	395493.BegalDRAFT_2461	1.18e-74	245.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4623I@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CcmF_C,Cytochrom_C_asm
k59_197248_2	395493.BegalDRAFT_2073	8.66e-65	225.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,4602D@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_104134_1	1168034.FH5T_20525	4.11e-116	341.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,2FNHF@200643|Bacteroidia	976|Bacteroidetes	M	Mannose-1-phosphate guanylyltransferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_34790_1	385682.AFSL01000009_gene2489	1.86e-47	172.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,3XIT2@558415|Marinilabiliaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_42392_1	2340.JV46_08940	4.7e-36	128.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1S0IN@1236|Gammaproteobacteria,1JA2Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulatory protein, C terminal	IV02_26825	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_42392_2	317025.Tcr_0005	2.48e-08	59.3	COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1T2MN@1236|Gammaproteobacteria,463U7@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_197257_1	1499686.BN1079_02975	2.25e-55	184.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN746.PP_0436	S4,tRNA-synt_1b
k59_235864_1	401053.AciPR4_0584	0.000252	48.5	COG3267@1|root,COG3267@2|Bacteria,3Y6P4@57723|Acidobacteria,2JKNX@204432|Acidobacteriia	204432|Acidobacteriia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_127595_1	661367.LLO_2343	6.74e-43	149.0	COG1376@1|root,COG1376@2|Bacteria,1RDA8@1224|Proteobacteria,1S4PD@1236|Gammaproteobacteria,1JCVH@118969|Legionellales	118969|Legionellales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_3883_1	96561.Dole_3068	1.76e-105	319.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MIVE@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_166301_1	1165841.SULAR_07670	1.58e-121	356.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,42ZSN@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_227932_1	926561.KB900617_gene1713	3.05e-09	65.5	COG0457@1|root,COG0760@1|root,COG0457@2|Bacteria,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,3WBSJ@53433|Halanaerobiales	186801|Clostridia	O	PPIC-type PPIASE domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
k59_119842_1	1165841.SULAR_05348	5.96e-67	225.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2YM9E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL,Patched
k59_73713_1	595460.RRSWK_00666	6.74e-14	72.4	COG0457@1|root,COG0457@2|Bacteria,2IXP3@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_16
k59_73713_2	344747.PM8797T_03940	1.39e-28	117.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_135575_1	1429851.X548_14030	2.31e-48	176.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1NAZC@1224|Proteobacteria,1S063@1236|Gammaproteobacteria,1X9P4@135614|Xanthomonadales	135614|Xanthomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_166798_1	1165841.SULAR_08899	5.62e-57	187.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1N7HT@1224|Proteobacteria,42RFF@68525|delta/epsilon subdivisions,2YP9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_166798_2	1165841.SULAR_08904	2.92e-29	109.0	COG3381@1|root,COG3381@2|Bacteria,1N4MX@1224|Proteobacteria,42RVB@68525|delta/epsilon subdivisions,2YP5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	component of anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_120260_1	1121878.AUGL01000005_gene2593	2.34e-10	58.5	COG2841@1|root,COG2841@2|Bacteria,1NGDM@1224|Proteobacteria,1SGWC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
k59_42790_1	530564.Psta_2542	8.6e-19	91.3	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_205238_1	1165841.SULAR_06303	5.56e-76	241.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_205238_2	1165841.SULAR_06298	4.49e-20	84.0	2ARMJ@1|root,31GY7@2|Bacteria,1QEMQ@1224|Proteobacteria,42VV2@68525|delta/epsilon subdivisions,2YQ9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_73720_1	1408418.JNJH01000043_gene3127	1.12e-42	154.0	2FITE@1|root,34AIX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_104515_1	1165841.SULAR_02003	1.96e-96	305.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_58135_1	1121918.ARWE01000001_gene60	8.55e-74	240.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,43BF5@68525|delta/epsilon subdivisions,2X6TI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_4333_1	555779.Dthio_PD1848	9.66e-90	285.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,430KD@68525|delta/epsilon subdivisions,2WVSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind
k59_104516_1	5741.EDO78549	1.38e-05	47.4	COG1132@1|root,KOG0054@2759|Eukaryota	5741.EDO78549|-	V	ATPase activity, coupled to transmembrane movement of substances	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_104516_2	335543.Sfum_4030	1.46e-37	134.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,42U8A@68525|delta/epsilon subdivisions,2WPZ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_243864_1	483219.LILAB_35800	4.62e-82	253.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_135580_1	1190606.AJYG01000100_gene1018	8.76e-91	278.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1XTU0@135623|Vibrionales	135623|Vibrionales	C	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_212988_1	1168034.FH5T_03830	1.41e-33	122.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_212988_2	1168034.FH5T_03825	7.55e-28	111.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,2FNZ8@200643|Bacteroidia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
k59_96931_1	998674.ATTE01000001_gene198	1.17e-65	218.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,45ZQY@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_150951_1	2340.JV46_11060	5.32e-53	174.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RMVZ@1236|Gammaproteobacteria,1J6K8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0247 Fe-S oxidoreductase	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
k59_150951_2	870187.Thini_2168	1.58e-29	116.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Iron-sulfur cluster binding protein	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_112496_1	1123508.JH636443_gene5001	3.74e-36	143.0	COG1404@1|root,COG2931@1|root,COG3210@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,2J2J4@203682|Planctomycetes	203682|Planctomycetes	OU	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
k59_58141_1	158500.BV97_05027	6.04e-40	150.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2TVB3@28211|Alphaproteobacteria,2K9MI@204457|Sphingomonadales	204457|Sphingomonadales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_96932_1	639282.DEFDS_1121	3.63e-19	89.4	COG1463@1|root,COG1463@2|Bacteria,2GEQX@200930|Deferribacteres	200930|Deferribacteres	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_96932_2	985867.AEWF01000001_gene1887	7.27e-30	112.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,47F9X@766|Rickettsiales	766|Rickettsiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_143547_1	382464.ABSI01000016_gene745	2.43e-10	58.5	COG2259@1|root,COG2259@2|Bacteria,46T2M@74201|Verrucomicrobia,2IUPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_143547_2	287.DR97_3447	1.24e-35	136.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1SYCQ@1236|Gammaproteobacteria,1YHKA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_220832_1	313596.RB2501_06860	2.05e-29	116.0	COG2133@1|root,COG2133@2|Bacteria,4PKAZ@976|Bacteroidetes,1IJ63@117743|Flavobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_220832_2	313596.RB2501_06865	2.91e-86	273.0	COG3064@1|root,COG3064@2|Bacteria,4NGJZ@976|Bacteroidetes,1HY5X@117743|Flavobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	sprD	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_220833_1	765913.ThidrDRAFT_0531	9.08e-55	177.0	COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,1RP1V@1236|Gammaproteobacteria,1WY2M@135613|Chromatiales	135613|Chromatiales	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
k59_220833_2	1042375.AFPL01000026_gene3624	2.25e-21	87.4	2E4CK@1|root,32Z81@2|Bacteria,1N7JR@1224|Proteobacteria,1SCEZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	With PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone	pqqD	-	-	ko:K06138	-	-	-	-	ko00000	-	-	-	PqqD
k59_220833_3	765913.ThidrDRAFT_0529	2.92e-25	102.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1WWJ4@135613|Chromatiales	135613|Chromatiales	S	Radical SAM superfamily	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_205261_1	1116472.MGMO_41c00410	3.82e-122	357.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1XDK4@135618|Methylococcales	135618|Methylococcales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_4347_1	761193.Runsl_2487	2.03e-83	273.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_189810_1	104623.Ser39006_01962	1.21e-17	87.0	COG3321@1|root,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria,401AU@613|Serratia	1236|Gammaproteobacteria	Q	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_189811_1	595494.Tola_2809	3.24e-66	205.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1Y4I0@135624|Aeromonadales	135624|Aeromonadales	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_96939_1	1156935.QWE_12088	1.34e-49	174.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,4B71R@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_166811_1	313596.RB2501_14229	1.06e-56	190.0	COG2885@1|root,COG2885@2|Bacteria,4PMAU@976|Bacteroidetes,1IJPT@117743|Flavobacteriia	976|Bacteroidetes	M	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_11898_1	535289.Dtpsy_1062	4.48e-15	76.3	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria,4AEPV@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	nosC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_182228_1	1538644.KO02_01420	3.14e-58	191.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	4.1.1.46	ko:K07045,ko:K14333	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821	RC00390	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2,DDE_Tnp_1_4
k59_166814_1	264732.Moth_0808	2.29e-23	105.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,24BZ3@186801|Clostridia,42GGS@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_189816_2	313596.RB2501_09880	7.52e-77	230.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1I18F@117743|Flavobacteriia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_189816_3	616991.JPOO01000003_gene1467	1.08e-35	126.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1HXI0@117743|Flavobacteriia,23GSY@178469|Arenibacter	976|Bacteroidetes	J	Ribosomal protein S3, C-terminal domain	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_27326_1	1168034.FH5T_09750	1.82e-39	135.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_27326_2	1168034.FH5T_09760	2.68e-32	125.0	COG2010@1|root,COG2993@1|root,COG3278@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_58155_1	977880.RALTA_A1040	1.73e-39	151.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,1JZXQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_89144_1	2340.JV46_04180	1.3e-70	233.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1J4IX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_138917_1	713586.KB900536_gene2551	1.92e-18	89.4	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,1WXQ5@135613|Chromatiales	135613|Chromatiales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_138921_1	1223410.KN050846_gene1306	7.72e-15	75.5	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_154418_1	2340.JV46_19210	3.28e-107	333.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08483,ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_7646_1	5811.TGME49_094820	1.27e-05	50.8	COG0318@1|root,COG1020@1|root,COG3321@1|root,KOG1178@2759|Eukaryota,KOG1202@2759|Eukaryota,KOG3628@2759|Eukaryota,3Y9H9@5794|Apicomplexa,3YJPA@5796|Coccidia,3YUQG@5809|Sarcocystidae	5794|Apicomplexa	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,AMP-binding,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NAD_binding_4,PP-binding,PS-DH,Sulfotransfer_3,ketoacyl-synt
k59_61693_1	1168034.FH5T_10065	3.28e-92	280.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,2FMRA@200643|Bacteroidia	976|Bacteroidetes	E	argininosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_193250_2	350058.Mvan_5177	1.4e-23	95.5	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria,239A7@1762|Mycobacteriaceae	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
k59_131443_1	1042377.AFPJ01000024_gene706	2.57e-56	191.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,465QH@72275|Alteromonadaceae	1236|Gammaproteobacteria	CP	COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k59_131444_1	870187.Thini_2837	1.65e-15	78.2	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,1RQCS@1236|Gammaproteobacteria,46267@72273|Thiotrichales	72273|Thiotrichales	C	Mg-protoporphyrin IX monomethyl ester oxidative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_131444_2	1117647.M5M_04995	1.35e-15	76.6	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,1RQB4@1236|Gammaproteobacteria,1J8QZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_46191_1	765869.BDW_06150	3.37e-30	120.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2MUA1@213481|Bdellovibrionales,2WNI2@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd,Pkinase
k59_100506_1	864702.OsccyDRAFT_2545	4.99e-57	199.0	COG0004@1|root,COG0642@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HHZA@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_31155_2	1250232.JQNJ01000001_gene2526	4.62e-21	88.6	2DRNY@1|root,32URC@2|Bacteria,4NST3@976|Bacteroidetes,1I448@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_116157_1	1205680.CAKO01000006_gene3157	3.2e-62	205.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2JPC2@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_239962_2	2340.JV46_17590	2.35e-44	147.0	2BE3G@1|root,327U6@2|Bacteria,1RI7X@1224|Proteobacteria,1S88B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239965_1	991905.SL003B_2986	4.55e-84	264.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,4BPMM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_54319_1	1128421.JAGA01000002_gene188	2.95e-17	79.7	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_31159_1	266762.HQ36_04825	2.16e-21	96.7	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,2FMR0@200643|Bacteroidia,22WA3@171551|Porphyromonadaceae	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_23333_1	344747.PM8797T_26170	3.24e-77	236.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k59_170358_1	870187.Thini_4336	1.59e-93	300.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RS9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_85211_1	997353.HMPREF9144_2633	6.74e-27	103.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_85211_2	1168034.FH5T_14400	7.26e-25	102.0	COG4213@1|root,COG4213@2|Bacteria,4NNBW@976|Bacteroidetes,2FWT8@200643|Bacteroidia	976|Bacteroidetes	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
k59_131670_1	1167006.UWK_00586	3.22e-64	207.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,42PXT@68525|delta/epsilon subdivisions,2WR2Y@28221|Deltaproteobacteria,2MNE7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_62059_1	1348583.ATLH01000023_gene593	9.04e-10	60.8	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HYSQ@117743|Flavobacteriia,1F8SG@104264|Cellulophaga	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_15605_1	1249627.D779_1426	2.51e-20	88.6	28T0P@1|root,2ZF9Z@2|Bacteria,1RAUV@1224|Proteobacteria,1S23D@1236|Gammaproteobacteria,1WY26@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15605_2	2340.JV46_03430	7.36e-24	95.1	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_131673_1	472759.Nhal_0691	4.06e-107	322.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1WWTN@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
k59_85220_1	452637.Oter_3167	1.71e-53	188.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_134_2	3712.Bo00673s130.1	7.29e-09	55.5	2D0J1@1|root,2SEDM@2759|Eukaryota,37XX0@33090|Viridiplantae,3GMNP@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123876_1	218851.Aquca_019_00205.1	0.0	1052.0	COG0086@1|root,2QPYA@2759|Eukaryota,37HSD@33090|Viridiplantae,3GDVE@35493|Streptophyta	35493|Streptophyta	K	RNA polymerase	rpoC2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_123876_2	4155.Migut.D01338.1.p	6.33e-163	456.0	COG0052@1|root,KOG0832@2759|Eukaryota,37S1B@33090|Viridiplantae,3GHIA@35493|Streptophyta,44SIK@71274|asterids	35493|Streptophyta	J	Ribosomal protein S2	rps2	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_123876_3	981085.XP_010100012.1	9.19e-163	457.0	COG0356@1|root,KOG4665@2759|Eukaryota,37MBD@33090|Viridiplantae,3GH9B@35493|Streptophyta,4JDXB@91835|fabids	35493|Streptophyta	C	it plays a direct role in the translocation of protons across the membrane	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009579,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098807,GO:0099131,GO:0099132,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_123876_5	218851.Aquca_038_00147.1	1.59e-43	142.0	COG0636@1|root,KOG0232@2759|Eukaryota,37W5A@33090|Viridiplantae,3GK4X@35493|Streptophyta	35493|Streptophyta	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_123876_6	3880.AES88228	3.47e-23	97.8	COG0052@1|root,COG0356@1|root,COG0636@1|root,KOG0232@2759|Eukaryota,KOG0832@2759|Eukaryota,KOG4665@2759|Eukaryota,37S1B@33090|Viridiplantae,3GHIA@35493|Streptophyta	35493|Streptophyta	J	ribosomal protein S2	rps2	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_123876_7	981085.XP_010100011.1	4.5e-69	214.0	COG0636@1|root,KOG0232@2759|Eukaryota	2759|Eukaryota	C	ATP hydrolysis coupled proton transport	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02155,ko:K02919	ko00190,ko00195,ko01100,ko03010,ko04142,ko04145,ko04721,ko04966,ko05110,ko05120,ko05152,ko05323,map00190,map00195,map01100,map03010,map04142,map04145,map04721,map04966,map05110,map05120,map05152,map05323	M00157,M00160,M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00194,ko03011	3.A.2.1,3.A.2.2	-	-	ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_123876_8	4572.TRIUR3_00082-P1	0.0	885.0	COG0056@1|root,KOG1353@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit alpha	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_123876_9	3880.AES87803	1.83e-15	71.2	2E3TA@1|root,2SAFC@2759|Eukaryota,37XB0@33090|Viridiplantae,3GKW4@35493|Streptophyta,4JVZD@91835|fabids	35493|Streptophyta	S	PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02710,ko:K02712	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbK
k59_123876_10	4155.Migut.G00430.1.p	2.59e-29	105.0	2E3TA@1|root,2SAFC@2759|Eukaryota,37XB0@33090|Viridiplantae,3GKW4@35493|Streptophyta	35493|Streptophyta	S	Photosystem II reaction center protein K	psbK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02710,ko:K02712	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbK
k59_123876_13	4155.Migut.H01168.1.p	4.89e-25	94.7	COG0228@1|root,KOG3419@2759|Eukaryota,37XEF@33090|Viridiplantae,3GM4M@35493|Streptophyta	35493|Streptophyta	J	Ribosomal protein S16	-	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_147117_1	1165841.SULAR_09644	9.15e-88	266.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_147117_2	1165841.SULAR_09649	2.08e-22	90.5	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_232262_2	887325.HMPREF0381_0786	6.39e-13	73.6	COG0500@1|root,COG1216@1|root,COG3266@1|root,COG0500@2|Bacteria,COG1216@2|Bacteria,COG3266@2|Bacteria,1UWFT@1239|Firmicutes,25KTU@186801|Clostridia,1HV5H@1164882|Lachnoanaerobaculum	186801|Clostridia	Q	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_162588_1	665952.HMPREF1015_02019	4.44e-05	51.2	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus	91061|Bacilli	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_46530_1	458817.Shal_2606	1.73e-45	161.0	COG3137@1|root,COG3137@2|Bacteria,1RCKQ@1224|Proteobacteria,1S0GK@1236|Gammaproteobacteria,2QA2B@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
k59_216806_1	118173.KB235914_gene2641	3.33e-12	68.6	2C3WA@1|root,2Z8P1@2|Bacteria,1G958@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108472_1	1156935.QWE_07231	1.48e-48	175.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,4B8TC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_224533_1	10228.TriadP33902	1.64e-07	47.8	2DZEY@1|root,2S6ZB@2759|Eukaryota,3A8VS@33154|Opisthokonta,3BUFV@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_224533_2	3847.GLYMA13G11980.1	3.54e-81	271.0	2CUMQ@1|root,2RN4M@2759|Eukaryota,37U2D@33090|Viridiplantae,3GX5D@35493|Streptophyta,4JTXP@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_224533_3	981085.XP_010106598.1	4.22e-29	110.0	2E13Y@1|root,2S8GD@2759|Eukaryota,38843@33090|Viridiplantae,3GW79@35493|Streptophyta,4JVE3@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131691_1	1165841.SULAR_05353	7.09e-138	407.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_201292_1	1408473.JHXO01000001_gene2095	1.15e-127	370.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,2FNZB@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_93028_1	1121935.AQXX01000086_gene5248	5.83e-76	240.0	COG1988@1|root,COG1988@2|Bacteria,1QK5N@1224|Proteobacteria,1S0MU@1236|Gammaproteobacteria,1XJQ8@135619|Oceanospirillales	135619|Oceanospirillales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_108478_1	1165841.SULAR_01435	2.96e-124	371.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,43B1H@68525|delta/epsilon subdivisions,2YT54@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_139526_1	1167006.UWK_01390	4.81e-58	197.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2WP86@28221|Deltaproteobacteria,2MP3J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfatase	-	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Sulfatase
k59_46538_1	1335757.SPICUR_01485	9.68e-87	280.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_216821_1	244582.JQAK01000006_gene2287	3.47e-32	115.0	COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,2UBXZ@28211|Alphaproteobacteria,47GGB@766|Rickettsiales	766|Rickettsiales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_216821_2	91604.ID47_07430	5.28e-98	292.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,47G6C@766|Rickettsiales	766|Rickettsiales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_201306_2	556269.ACDQ01000019_gene812	1.5e-31	115.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,472CA@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_193568_1	1323663.AROI01000009_gene3745	1.33e-37	137.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1RNV8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_157_1	1165841.SULAR_08879	4.18e-93	286.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2YS4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
k59_49779_1	1168034.FH5T_04250	5.21e-84	270.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein, OMP85 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_11245_1	1165841.SULAR_04212	1.45e-89	269.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189101_1	1121033.AUCF01000021_gene2886	7.29e-92	301.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQPR@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_166043_1	1223544.GSI01S_38_00140	3.49e-06	50.8	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4GCND@85026|Gordoniaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_18639_1	358220.C380_06880	0.000166	51.2	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4AAFC@80864|Comamonadaceae	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_88488_1	1122599.AUGR01000010_gene1004	3.86e-70	219.0	COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,1XJVM@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF599
k59_197029_1	1168034.FH5T_06510	4.26e-93	276.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,2FMX9@200643|Bacteroidia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_72975_1	251221.35211899	2.24e-36	138.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
k59_72976_1	861299.J421_0276	1.79e-25	106.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_8
k59_127379_1	1235788.C802_02759	4.29e-07	55.5	COG0535@1|root,COG0535@2|Bacteria,4NMXM@976|Bacteroidetes,2FPWE@200643|Bacteroidia,4APWD@815|Bacteroidaceae	976|Bacteroidetes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_11253_1	2340.JV46_10870	4.04e-211	609.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1J4DR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_227725_1	477228.YO5_13996	5.6e-35	138.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,1RP39@1236|Gammaproteobacteria,1Z15R@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	ycaD	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_189662_1	99598.Cal7507_6044	4.62e-53	181.0	COG3385@1|root,COG3385@2|Bacteria,1GBUK@1117|Cyanobacteria,1HK07@1161|Nostocales	1117|Cyanobacteria	L	SPTR Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Dimer_Tnp_Tn5
k59_182081_1	1165841.SULAR_04117	2.45e-55	188.0	COG1196@1|root,COG1196@2|Bacteria,1QUJ1@1224|Proteobacteria,42P7I@68525|delta/epsilon subdivisions,2YMKS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
k59_243759_1	266117.Rxyl_0026	1.9e-08	57.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
k59_73565_1	380703.AHA_1927	4.81e-71	238.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1Y42A@135624|Aeromonadales	135624|Aeromonadales	C	dehydrogenase, E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_27193_1	1123400.KB904747_gene434	7.34e-20	93.6	COG1353@1|root,COG1353@2|Bacteria,1RKFG@1224|Proteobacteria,1SSQS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	crispr-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120151_1	396588.Tgr7_0941	5.85e-94	296.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_166629_1	1232437.KL662010_gene1616	1.49e-106	317.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42QQQ@68525|delta/epsilon subdivisions,2WMBP@28221|Deltaproteobacteria,2MIM7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_143431_2	7668.SPU_003151-tr	5.13e-22	97.1	KOG1075@1|root,KOG1075@2759|Eukaryota,3A7X5@33154|Opisthokonta,3BTPZ@33208|Metazoa,3D9N3@33213|Bilateria	33208|Metazoa	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1891,RVT_1
k59_158694_1	452637.Oter_0461	6.95e-23	99.8	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,46UMD@74201|Verrucomicrobia,3K9AQ@414999|Opitutae	414999|Opitutae	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
k59_158694_2	1158602.I590_04125	2.13e-07	53.9	COG0454@1|root,COG0456@2|Bacteria,1VEHB@1239|Firmicutes,4HQT2@91061|Bacilli,4B2MV@81852|Enterococcaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_11787_2	13689.BV96_04737	8.41e-106	344.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,2K3E1@204457|Sphingomonadales	204457|Sphingomonadales	L	Protein involved in recombinase activity and DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_96825_1	1100720.ALKN01000017_gene1712	3.68e-31	117.0	COG2963@1|root,COG2963@2|Bacteria,1RIC7@1224|Proteobacteria,2VTQ4@28216|Betaproteobacteria,4AJRS@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_96825_2	1485545.JQLW01000010_gene1491	9.73e-132	387.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32,rve,rve_3
k59_73574_1	398720.MED217_01280	2.52e-08	60.5	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1HZGJ@117743|Flavobacteriia,2XI32@283735|Leeuwenhoekiella	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_189693_1	1111728.ATYS01000034_gene20	2.14e-30	119.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_189693_2	118168.MC7420_5070	5.54e-17	79.0	COG0615@1|root,COG0615@2|Bacteria,1G8ZG@1117|Cyanobacteria,1HC32@1150|Oscillatoriales	1117|Cyanobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_143435_1	1165841.SULAR_09479	5.42e-56	182.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_228268_1	391615.ABSJ01000002_gene527	4.11e-88	274.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1J4G5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
k59_205162_1	322710.Avin_16070	6.63e-20	93.6	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RXZA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway, component PulD	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_50331_1	344747.PM8797T_15666	1.26e-56	198.0	COG0515@1|root,COG0683@1|root,COG0515@2|Bacteria,COG0683@2|Bacteria,2IYX7@203682|Planctomycetes	203682|Planctomycetes	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6,Pkinase
k59_120177_2	322710.Avin_16150	1.17e-27	107.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S69B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	general secretion pathway protein	gspG_2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_35118_2	349124.Hhal_0149	3.8e-136	407.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1WXBU@135613|Chromatiales	135613|Chromatiales	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
k59_243800_1	443255.SCLAV_5116	1.72e-46	162.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k59_143446_3	1268239.PALB_27060	4.02e-07	50.4	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,2Q0KI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	iPC815.YPO1374	Pyr_redox_2
k59_220744_1	1173027.Mic7113_4040	2.2e-80	275.0	COG0515@1|root,COG2114@1|root,COG2202@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,Guanylate_cyc,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
k59_42728_1	1168034.FH5T_16690	1.11e-107	318.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,2FPGW@200643|Bacteroidia	976|Bacteroidetes	E	Threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_112429_1	1408473.JHXO01000005_gene1859	1.19e-93	290.0	COG1883@1|root,COG1883@2|Bacteria,4NH3V@976|Bacteroidetes,2FMSY@200643|Bacteroidia	976|Bacteroidetes	C	decarboxylase beta subunit	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_27237_1	396588.Tgr7_0824	7.86e-63	209.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales	135613|Chromatiales	T	SMART Nucleotide binding protein, PINc	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_236222_1	1429767.W6B178_9CAUD	2.45e-49	166.0	4QCUB@10239|Viruses,4QYNV@35237|dsDNA viruses  no RNA stage,4QRVM@28883|Caudovirales,4QNUK@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_4245_1	83406.HDN1F_01990	9.39e-18	78.6	COG3436@1|root,COG3436@2|Bacteria,1N638@1224|Proteobacteria,1SFHC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
k59_4245_2	1535422.ND16A_0183	1.54e-158	469.0	COG3316@1|root,COG3316@2|Bacteria	1535422.ND16A_0183|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_50356_1	565045.NOR51B_1278	1.48e-88	272.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_50356_2	123899.JPQP01000001_gene1593	6.82e-14	70.5	COG2893@1|root,COG2893@2|Bacteria,1PSXI@1224|Proteobacteria,2VUF1@28216|Betaproteobacteria,3T4VY@506|Alcaligenaceae	28216|Betaproteobacteria	G	COG2893 Phosphotransferase system, mannose fructose-specific component IIA	manX	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
k59_35139_1	1128421.JAGA01000003_gene3441	8.09e-90	277.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
k59_112431_1	195250.CM001776_gene509	6.86e-37	140.0	COG0405@1|root,COG0405@2|Bacteria,1G20A@1117|Cyanobacteria,1H3YR@1129|Synechococcus	1117|Cyanobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_143456_1	290397.Adeh_0313	3.5e-86	257.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WP90@28221|Deltaproteobacteria,2YVP3@29|Myxococcales	28221|Deltaproteobacteria	O	Alkyl hydroperoxide reductase	prx-1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_143460_1	1165841.SULAR_00480	3.25e-115	337.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2YMYR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_174142_1	1165841.SULAR_08337	2.13e-21	86.3	29D34@1|root,30016@2|Bacteria,1Q5ZK@1224|Proteobacteria,43250@68525|delta/epsilon subdivisions,2YSH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174142_2	387092.NIS_1827	3.56e-35	133.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	ko:K16076,ko:K18093	ko01501,ko02020,map01501,map02020	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.1.4,1.B.1.1.5,1.B.25.1.1	-	-	OprD,Porin_4
k59_89059_1	1123037.AUDE01000015_gene2598	6.43e-17	87.0	COG1345@1|root,COG1361@1|root,COG2866@1|root,COG3227@1|root,COG3420@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG2866@2|Bacteria,COG3227@2|Bacteria,COG3420@2|Bacteria,4NHMH@976|Bacteroidetes	976|Bacteroidetes	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
k59_236233_1	1500893.JQNB01000001_gene714	9.85e-60	200.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1X4KT@135614|Xanthomonadales	135614|Xanthomonadales	O	Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_104453_1	471854.Dfer_0264	1.48e-13	75.5	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
k59_104453_2	1168034.FH5T_05565	1.12e-27	109.0	COG5026@1|root,COG5026@2|Bacteria,4NIN0@976|Bacteroidetes,2FQ47@200643|Bacteroidia	976|Bacteroidetes	G	Hexokinase	-	-	2.7.1.1	ko:K00844	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04910,ko04930,ko04973,ko05230,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200,map04066,map04910,map04930,map04973,map05230	M00001,M00549	R00299,R00760,R00867,R01326,R01600,R01786,R01961,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	Hexokinase_1,Hexokinase_2
k59_73596_1	1168034.FH5T_05790	3.57e-127	368.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,2FPCB@200643|Bacteroidia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_158741_1	1120966.AUBU01000008_gene2397	2.57e-47	171.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_243808_2	1168034.FH5T_17600	5.32e-49	169.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,2FMEM@200643|Bacteroidia	976|Bacteroidetes	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
k59_11819_1	46429.BV95_00195	5.4e-37	144.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,2K3HH@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_4267_1	1165841.SULAR_02668	8.38e-155	440.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_65911_1	387093.SUN_0111	4.97e-17	75.1	COG0314@1|root,COG0314@2|Bacteria,1Q97D@1224|Proteobacteria,42REX@68525|delta/epsilon subdivisions,2YP4E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_46262_1	1028800.RG540_PA09950	5.96e-69	222.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria,4BM5H@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_15072_1	1521187.JPIM01000006_gene1741	7.43e-06	53.5	COG2227@1|root,COG2227@2|Bacteria,2G9HD@200795|Chloroflexi,375RS@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_193335_1	2340.JV46_27820	1.01e-51	176.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1J4J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_193335_2	2340.JV46_27920	1.07e-46	155.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_177639_2	313596.RB2501_06560	2.56e-32	112.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_177639_3	313596.RB2501_06555	3.99e-18	79.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_193341_1	1168034.FH5T_10410	1.13e-131	413.0	COG0841@1|root,COG1131@1|root,COG0841@2|Bacteria,COG1131@2|Bacteria,4NF8M@976|Bacteroidetes,2FQY7@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ACR_tran
k59_193349_1	1165841.SULAR_07400	2.44e-69	213.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SSI@68525|delta/epsilon subdivisions,2YPDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_208725_1	1322246.BN4_20153	1.05e-26	112.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_69611_1	1168034.FH5T_12025	3.08e-99	297.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,2FUUQ@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_216390_1	1278309.KB907099_gene2913	2.34e-60	215.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53975_1	518766.Rmar_2560	3.05e-69	240.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1FIS3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_84807_2	1216007.AOPM01000027_gene3617	6.51e-29	115.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,2Q0HC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_154501_2	313596.RB2501_05790	3.82e-136	389.0	COG3279@1|root,COG3279@2|Bacteria,4NEXZ@976|Bacteroidetes,1HZ0B@117743|Flavobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_224317_1	313603.FB2170_14253	3.7e-55	183.0	2E3AK@1|root,2ZC5I@2|Bacteria,4NMX3@976|Bacteroidetes,1I1BU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_69625_1	1115632.JAFW01000001_gene551	2.64e-06	55.8	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,1W9BW@1268|Micrococcaceae	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_193362_1	1089550.ATTH01000001_gene1152	1.74e-67	219.0	COG0281@1|root,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1FJXT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
k59_162348_1	1335757.SPICUR_07775	3.32e-12	66.6	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1WXKK@135613|Chromatiales	135613|Chromatiales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_61801_1	688270.Celal_2585	1.37e-58	184.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia,1F948@104264|Cellulophaga	976|Bacteroidetes	J	PFAM Translation initiation factor IF-3, C-terminal domain	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_177671_1	4081.Solyc00g022100.1.1	2.92e-106	307.0	2CXQU@1|root,2S4M6@2759|Eukaryota,37WA9@33090|Viridiplantae,3GKQA@35493|Streptophyta	35493|Streptophyta	-	-	rpl10	-	-	-	-	-	-	-	-	-	-	-	-
k59_247323_1	1298867.AUES01000051_gene4511	1.69e-26	115.0	COG0771@1|root,COG2931@1|root,COG4625@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3K2H3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
k59_162357_2	489825.LYNGBM3L_01330	6.68e-17	75.9	2E14K@1|root,32WJQ@2|Bacteria,1G825@1117|Cyanobacteria,1HGGM@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239762_1	686340.Metal_1459	4.47e-12	65.1	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1XEXB@135618|Methylococcales	135618|Methylococcales	G	PFAM Haloacid dehalogenase-like hydrolase	-	-	3.1.3.105,3.1.3.18	ko:K01091,ko:K22292	ko00520,ko00630,ko01100,ko01110,ko01130,map00520,map00630,map01100,map01110,map01130	-	R01334,R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_239762_2	1450525.JATV01000006_gene1018	9.39e-18	81.3	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,1I45Z@117743|Flavobacteriia,2NX3W@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
k59_139036_1	1165841.SULAR_06938	3.39e-81	240.0	COG1145@1|root,COG1145@2|Bacteria,1QZ2K@1224|Proteobacteria,42SFI@68525|delta/epsilon subdivisions,2YPQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_247334_1	290397.Adeh_3063	1.48e-31	129.0	COG5295@1|root,COG5295@2|Bacteria,1QVUF@1224|Proteobacteria	1224|Proteobacteria	UW	this gene contains a nucleotide ambiguity which may be the result of a sequencing error	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin
k59_185646_1	1238450.VIBNISOn1_1350038	1.38e-66	208.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,1XXW0@135623|Vibrionales	135623|Vibrionales	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
k59_208772_1	1165841.SULAR_00525	8.24e-26	98.6	COG1846@1|root,COG1846@2|Bacteria,1ND45@1224|Proteobacteria,42UP2@68525|delta/epsilon subdivisions,2YQ0G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
k59_208772_2	1165841.SULAR_00530	1.11e-117	338.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42RV5@68525|delta/epsilon subdivisions,2YP89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_208772_3	1165841.SULAR_00535	1.09e-18	82.8	COG3384@1|root,COG3384@2|Bacteria,1RB6Z@1224|Proteobacteria,43ACS@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_92584_2	1530186.JQEY01000017_gene264	4.96e-10	59.3	COG5606@1|root,COG5606@2|Bacteria,1NA3S@1224|Proteobacteria,2UF4K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
k59_46304_1	1218075.BAYA01000015_gene4285	1.45e-60	197.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2VJ2R@28216|Betaproteobacteria,1K3YI@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_185651_1	146922.JOFU01000052_gene2282	0.00042	44.7	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_216451_1	1121104.AQXH01000006_gene2332	4.07e-68	218.0	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes,1IYDP@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_115948_1	745014.OMB55_00006310	1.26e-51	183.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_23098_2	1232410.KI421425_gene1544	1.08e-63	199.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,43V5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_84850_1	1165841.SULAR_04167	4.84e-90	278.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_84850_2	1165841.SULAR_04157	1.22e-51	173.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_139067_1	177437.HRM2_30650	3.33e-69	219.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_108083_1	765913.ThidrDRAFT_3979	6.88e-119	352.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1WW4Q@135613|Chromatiales	135613|Chromatiales	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_108083_2	329726.AM1_4752	3.03e-11	62.8	COG0625@1|root,COG0625@2|Bacteria,1G1XI@1117|Cyanobacteria	1117|Cyanobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_N,GST_N_3
k59_185657_1	1121904.ARBP01000012_gene1371	9.69e-40	150.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47KYP@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
k59_139070_1	1165841.SULAR_00245	2.27e-94	278.0	COG0745@1|root,COG0745@2|Bacteria,1Q4KJ@1224|Proteobacteria,42ZD8@68525|delta/epsilon subdivisions,2YRA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
k59_108086_1	751994.AGIG01000034_gene445	1.67e-29	113.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1S7KS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_54024_1	1165841.SULAR_00900	1.52e-45	157.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42QN4@68525|delta/epsilon subdivisions,2YTQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_108089_1	1165841.SULAR_05283	1.51e-112	338.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_92608_1	1165841.SULAR_09179	2.26e-68	227.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07648,ko:K07679	ko02020,ko02026,ko05133,map02020,map02026,map05133	M00456,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF_2,HATPase_c,HisKA,Hpt,PAS,Response_reg
k59_239796_1	981085.XP_010087824.1	0.000152	46.2	COG1643@1|root,KOG0920@2759|Eukaryota,37KD0@33090|Viridiplantae,3G8MK@35493|Streptophyta,4JD5Y@91835|fabids	35493|Streptophyta	A	ATP-dependent RNA helicase	-	GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0001012,GO:0001047,GO:0001067,GO:0001503,GO:0001817,GO:0001819,GO:0002151,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0003724,GO:0003725,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006725,GO:0006807,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009605,GO:0009607,GO:0009615,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010638,GO:0014070,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032204,GO:0032206,GO:0032479,GO:0032481,GO:0032501,GO:0032647,GO:0032727,GO:0032879,GO:0032880,GO:0033043,GO:0033044,GO:0034641,GO:0042221,GO:0042623,GO:0042826,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043330,GO:0043331,GO:0043487,GO:0043489,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051052,GO:0051054,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051707,GO:0051880,GO:0060255,GO:0065007,GO:0065008,GO:0070034,GO:0070035,GO:0070201,GO:0071704,GO:0080090,GO:0090087,GO:0090304,GO:0090669,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901698,GO:1902369,GO:1902680,GO:1902739,GO:1902741,GO:1903506,GO:1903508,GO:1903530,GO:1903532,GO:1904951,GO:1990837,GO:2000112,GO:2001141,GO:2001252	3.6.4.13	ko:K14442	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,HA2,Helicase_C,OB_NTP_bind,dsrm
k59_216471_1	313596.RB2501_08920	1.53e-64	209.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1HXI4@117743|Flavobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_216471_2	313603.FB2170_08539	2.3e-21	92.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia,2PG1B@252356|Maribacter	976|Bacteroidetes	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_23111_1	111781.Lepto7376_2714	1.66e-49	179.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase,Response_reg
k59_239804_1	1168034.FH5T_21045	5.4e-73	224.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_193404_1	204669.Acid345_4410	4.64e-13	71.6	COG0352@1|root,COG0352@2|Bacteria,3Y53Y@57723|Acidobacteria,2JJTS@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_162399_1	2340.JV46_16110	1.44e-127	399.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_92615_1	870187.Thini_0800	4.33e-144	418.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cofactor biosynthesis protein NifB	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Fer4_14,Nitro_FeMo-Co,Radical_SAM
k59_15148_1	530564.Psta_2636	7.57e-46	166.0	COG1520@1|root,COG1520@2|Bacteria,2IYAV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_154552_1	1121904.ARBP01000021_gene3609	7.5e-18	85.5	COG0657@1|root,COG0657@2|Bacteria,4NWD5@976|Bacteroidetes	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_61861_1	316067.Geob_3224	8.05e-33	129.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,42V8Q@68525|delta/epsilon subdivisions,2WRSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k59_147379_1	395493.BegalDRAFT_0207	3.43e-70	237.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T4BF@1236|Gammaproteobacteria	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	chiS	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg,Y_Y_Y
k59_3161_2	2340.JV46_25070	7.7e-34	128.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1J4NF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_80420_1	472759.Nhal_2377	6.44e-28	103.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1WYGN@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_80420_2	279714.FuraDRAFT_3869	1.6e-18	84.7	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KQ2X@206351|Neisseriales	206351|Neisseriales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_188700_1	2340.JV46_06570	1.7e-213	614.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_227253_1	745718.JADT01000002_gene2355	2.3e-12	63.2	COG3205@1|root,COG3205@2|Bacteria,4NV6E@976|Bacteroidetes,1I4TA@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
k59_227253_2	697281.Mahau_0407	4.85e-26	104.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_165660_1	395493.BegalDRAFT_0987	3.05e-160	474.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales	72273|Thiotrichales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_80423_1	1283300.ATXB01000001_gene423	4.22e-89	270.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1XE6M@135618|Methylococcales	135618|Methylococcales	S	PFAM Polyphosphate kinase 2	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_149911_1	1266914.ATUK01000004_gene1683	2.35e-33	122.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,1RMCB@1236|Gammaproteobacteria,1WXPS@135613|Chromatiales	135613|Chromatiales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_149911_2	760117.JN27_05145	1.64e-51	179.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VIT6@28216|Betaproteobacteria,472YH@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_111327_1	264462.Bd0334	2.03e-74	239.0	COG1816@1|root,COG1816@2|Bacteria,1R7EK@1224|Proteobacteria,42MHV@68525|delta/epsilon subdivisions,2MSQX@213481|Bdellovibrionales,2WMI4@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Adenosine/AMP deaminase	-	-	-	-	-	-	-	-	-	-	-	-	A_deaminase
k59_3165_2	637389.Acaty_c1716	1.79e-09	55.5	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,1SGGE@1236|Gammaproteobacteria,2NDE2@225057|Acidithiobacillales	225057|Acidithiobacillales	C	PFAM Heavy metal transport detoxification protein	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_3165_3	1492922.GY26_15365	6.58e-08	54.7	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J57S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	cation transport ATPase	copA	GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035434,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060003,GO:0061687,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071292,GO:0071944,GO:0090662,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0099131,GO:1902601,GO:1990169	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	iEC55989_1330.EC55989_0497,iECIAI1_1343.ECIAI1_0487,iECO103_1326.ECO103_0460,iECSE_1348.ECSE_0509,iECW_1372.ECW_m0557,iEKO11_1354.EKO11_3363,iWFL_1372.ECW_m0557	E1-E2_ATPase,HMA,Hydrolase
k59_18266_1	1177179.A11A3_17115	4.65e-143	408.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,1XP53@135619|Oceanospirillales	135619|Oceanospirillales	L	overlaps another CDS with the same product name	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_18266_2	642227.HA49_07400	8.32e-08	49.7	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S6KR@1236|Gammaproteobacteria,4BVUF@82986|Tatumella	1236|Gammaproteobacteria	L	Helix-turn-helix domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_242812_1	67275.JOAP01000039_gene3373	2.08e-49	178.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_165669_1	1123228.AUIH01000001_gene1352	2.09e-70	242.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1R4VM@1224|Proteobacteria,1RQVY@1236|Gammaproteobacteria,1XJTK@135619|Oceanospirillales	135619|Oceanospirillales	U	alginic acid biosynthetic process	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Laminin_G_3
k59_204172_1	313596.RB2501_07460	2.06e-114	341.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_242814_1	1167006.UWK_03232	1.51e-09	58.5	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,42SAA@68525|delta/epsilon subdivisions,2WPCM@28221|Deltaproteobacteria,2MJTD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methyltransferase small domain	-	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
k59_242814_2	404380.Gbem_3436	6.59e-16	75.9	COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria,42TK4@68525|delta/epsilon subdivisions,2WQQS@28221|Deltaproteobacteria,43VF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_111337_1	617140.AJZE01000072_gene838	5.29e-57	196.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1SM5A@1236|Gammaproteobacteria,1XVNU@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_173204_1	2340.JV46_06770	5.92e-94	284.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1J622@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_149916_1	1031288.AXAA01000001_gene2222	9.98e-06	48.5	COG1149@1|root,COG1149@2|Bacteria,1TQI9@1239|Firmicutes,2484J@186801|Clostridia,36GNU@31979|Clostridiaceae	186801|Clostridia	C	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k59_149916_2	1408473.JHXO01000007_gene925	5.94e-37	135.0	COG0477@1|root,COG2814@2|Bacteria,4PADM@976|Bacteroidetes,2FX70@200643|Bacteroidia	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_34232_1	65497.JODV01000011_gene2448	2.78e-61	211.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4DYSA@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_142349_1	1444711.CCJF01000005_gene690	4.18e-80	246.0	COG0214@1|root,COG0214@2|Bacteria,2JGS5@204428|Chlamydiae	204428|Chlamydiae	H	SOR/SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k59_242820_1	272560.BPSL0996	4.86e-33	123.0	COG2072@1|root,COG2072@2|Bacteria,1N59U@1224|Proteobacteria	1224|Proteobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_134453_1	411154.GFO_1940	5.58e-103	313.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,1HZCZ@117743|Flavobacteriia	976|Bacteroidetes	S	Putative modulator of DNA gyrase	tldD3	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_142354_1	1165841.SULAR_08427	9.02e-111	325.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2YMNC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_235267_1	72664.XP_006392428.1	2.05e-108	355.0	28Q0M@1|root,2QWP8@2759|Eukaryota,37SGC@33090|Viridiplantae,3G8GC@35493|Streptophyta	35493|Streptophyta	S	Zinc knuckle family protein	-	-	-	-	-	-	-	-	-	-	-	-	MP,RVP,zf-CCHC
k59_49379_1	1165841.SULAR_08487	1.67e-113	333.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_142359_1	1122614.JHZF01000013_gene3247	5.65e-50	172.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,2TU2W@28211|Alphaproteobacteria,2PC7W@252301|Oceanicola	28211|Alphaproteobacteria	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
k59_204192_1	1165841.SULAR_07770	7.86e-133	392.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_34242_1	981085.XP_010093664.1	1.05e-139	421.0	COG0480@1|root,KOG0465@2759|Eukaryota,37K55@33090|Viridiplantae,3G82M@35493|Streptophyta,4JJGU@91835|fabids	35493|Streptophyta	J	Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006996,GO:0007275,GO:0008144,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009657,GO:0009658,GO:0009791,GO:0009845,GO:0009941,GO:0009987,GO:0016043,GO:0017076,GO:0030554,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0048856,GO:0071840,GO:0090351,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_211864_1	1158146.KB907129_gene1987	0.000588	46.2	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1WYD5@135613|Chromatiales	135613|Chromatiales	T	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,SH3_3
k59_88084_1	29730.Gorai.007G237900.1	9.26e-06	43.9	2EQ7X@1|root,2ST9U@2759|Eukaryota,3819J@33090|Viridiplantae,3GQNF@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_157729_1	1026955.F5B412_9CAUD	8.5e-143	442.0	4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses  no RNA stage,4QPWY@28883|Caudovirales,4QHVQ@10662|Myoviridae	10662|Myoviridae	S	nucleotide binding	-	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	-
k59_88087_1	78898.MVEG_01866T0	1.77e-47	162.0	COG0625@1|root,KOG0868@2759|Eukaryota,39R80@33154|Opisthokonta,3P36F@4751|Fungi,1GTWF@112252|Fungi incertae sedis	4751|Fungi	O	Glutathione S-transferase, N-terminal domain	-	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016034,GO:0016054,GO:0016853,GO:0016859,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	5.2.1.2	ko:K01800	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_C,GST_C_3,GST_N,GST_N_2,GST_N_3
k59_3208_1	1121920.AUAU01000007_gene559	3.62e-60	205.0	COG0784@1|root,COG1100@1|root,COG3852@1|root,COG0784@2|Bacteria,COG1100@2|Bacteria,COG3852@2|Bacteria,3Y9EH@57723|Acidobacteria	57723|Acidobacteria	T	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Ras,Response_reg
k59_80444_1	583355.Caka_0258	4.21e-21	93.2	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_181102_1	2340.JV46_15670	1.22e-101	302.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1J4H1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_181102_2	1283300.ATXB01000001_gene2012	2.12e-27	105.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1XF50@135618|Methylococcales	135618|Methylococcales	F	Phosphoribosyl transferase domain	-	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_26220_1	768671.ThimaDRAFT_0841	8.69e-84	265.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales	135613|Chromatiales	O	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Trans_reg_C
k59_49394_1	1168034.FH5T_09695	6.49e-62	204.0	COG0526@1|root,COG0526@2|Bacteria,4NNSW@976|Bacteroidetes,2FXHS@200643|Bacteroidia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
k59_142373_2	768671.ThimaDRAFT_1715	8.44e-68	213.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_196600_1	9371.XP_004707458.1	1.99e-44	169.0	COG1331@1|root,KOG2244@2759|Eukaryota,38VM1@33154|Opisthokonta,3BDEY@33208|Metazoa,3CTDG@33213|Bilateria,489FR@7711|Chordata,4910U@7742|Vertebrata,3J43A@40674|Mammalia,350QK@311790|Afrotheria	33208|Metazoa	O	Spermatogenesis-associated protein 20	SPATA20	GO:0000003,GO:0007276,GO:0007283,GO:0008150,GO:0019953,GO:0022414,GO:0032501,GO:0032504,GO:0044703,GO:0048232,GO:0048609,GO:0051704	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_64917_2	373994.Riv7116_0790	2.48e-19	84.3	2C3ZQ@1|root,32SCF@2|Bacteria,1G6WP@1117|Cyanobacteria,1HP29@1161|Nostocales	1117|Cyanobacteria	S	MEKHLA domain	-	-	-	-	-	-	-	-	-	-	-	-	MEKHLA
k59_41758_2	1589733.A0A0C5AMU8_9CAUD	3.86e-26	108.0	4QAX9@10239|Viruses,4QPQH@28883|Caudovirales,4QHWN@10662|Myoviridae	10662|Myoviridae	S	T4 bacteriophage base plate protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41758_4	1493508.A0A0E3F279_9CAUD	1.25e-46	155.0	4QDXQ@10239|Viruses,4QQF2@28883|Caudovirales,4QIMB@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_196605_1	1278309.KB907101_gene393	1.07e-90	293.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XI50@135619|Oceanospirillales	135619|Oceanospirillales	S	exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_80447_1	504487.JCM19302_2182	8.82e-59	203.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
k59_18295_1	857087.Metme_1124	6.71e-41	154.0	COG0515@1|root,COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
k59_49399_1	2340.JV46_02620	2.04e-22	93.2	COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,1RQ0M@1236|Gammaproteobacteria,1JA3Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Prolyl 4-hydroxylase alpha subunit homologues.	ybiX	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
k59_80892_1	765911.Thivi_4140	9.03e-102	303.0	COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,1S58V@1236|Gammaproteobacteria,1X0Q7@135613|Chromatiales	135613|Chromatiales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_142839_1	882378.RBRH_00405	1.02e-21	100.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,1JZPD@119060|Burkholderiaceae	28216|Betaproteobacteria	M	surface antigen variable number repeat protein	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k59_142841_1	1469607.KK073768_gene3659	8.1e-30	122.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1G2A0@1117|Cyanobacteria,1HTVJ@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,Response_reg
k59_42160_2	1198452.Jab_1c08880	2.44e-24	105.0	COG0457@1|root,COG2199@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1R2E9@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_12
k59_72997_1	2340.JV46_20750	9.27e-16	71.6	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1JBC6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
k59_72997_2	2340.JV46_20740	5.17e-41	144.0	COG0845@1|root,COG0845@2|Bacteria,1R9JJ@1224|Proteobacteria,1S1HQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18901	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_166057_1	388413.ALPR1_19728	4.49e-15	76.6	COG0561@1|root,COG0561@2|Bacteria,4PMMP@976|Bacteroidetes	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_166057_2	929562.Emtol_1624	7.16e-15	76.3	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47Y5V@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_134959_1	1165841.SULAR_00085	4.74e-125	367.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_96320_2	1168034.FH5T_15310	1.02e-70	229.0	COG2866@1|root,COG2866@2|Bacteria,4NH4I@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_173644_1	1026970.XP_008823244.1	2.82e-09	65.5	KOG2401@1|root,KOG2401@2759|Eukaryota,39R9J@33154|Opisthokonta,3CNQA@33208|Metazoa,3E4W6@33213|Bilateria,48R2T@7711|Chordata,49MNV@7742|Vertebrata,3JPYT@40674|Mammalia	33208|Metazoa	L	AAA domain	N4BP2L2	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k59_181496_1	575586.HMPREF0016_02299	6.41e-14	77.4	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,3NT4F@468|Moraxellaceae	1236|Gammaproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_227736_1	1254432.SCE1572_16000	3.5e-44	163.0	COG3386@1|root,COG3386@2|Bacteria,1QUU9@1224|Proteobacteria,42ZTS@68525|delta/epsilon subdivisions,2WVGZ@28221|Deltaproteobacteria,2YZAH@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_21528_1	118173.KB235914_gene874	3.26e-22	100.0	COG4615@1|root,COG4615@2|Bacteria,1G2TH@1117|Cyanobacteria,1H8MF@1150|Oscillatoriales	1117|Cyanobacteria	V	Cyclic peptide transporter	-	-	-	ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2	-	-	ABC_membrane,ABC_tran
k59_99115_1	666685.R2APBS1_0820	1.13e-08	57.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X3II@135614|Xanthomonadales	135614|Xanthomonadales	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_21529_2	268748.Q58N56_BPPRP	9.68e-63	199.0	4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses  no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215032_2	543632.JOJL01000084_gene1908	6.04e-29	124.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
k59_137540_1	589865.DaAHT2_2599	5.32e-158	462.0	COG3385@1|root,COG3385@2|Bacteria,1R8CS@1224|Proteobacteria,42P9F@68525|delta/epsilon subdivisions,2WKTA@28221|Deltaproteobacteria,2MJAY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_2
k59_215033_2	441769.ABFU01000070_gene2054	5.13e-13	71.2	COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,4HC07@91061|Bacilli,1ZQUF@1386|Bacillus	91061|Bacilli	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_238296_1	616991.JPOO01000001_gene4193	3.7e-15	79.7	COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1HZT9@117743|Flavobacteriia,23H03@178469|Arenibacter	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_52472_1	1168034.FH5T_09570	2.95e-104	305.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,2FM71@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_160853_1	472759.Nhal_2027	1.5e-82	263.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,1RS1G@1236|Gammaproteobacteria,1WXVJ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_114436_1	1121405.dsmv_2161	1.44e-105	320.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_114439_1	41431.PCC8801_0479	3.29e-34	130.0	2BT7C@1|root,32NCP@2|Bacteria,1GGKB@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
k59_75960_2	1283340.Q6WHE3_BPKVM	4.26e-47	164.0	4QAWI@10239|Viruses,4QW40@35237|dsDNA viruses  no RNA stage,4QPUX@28883|Caudovirales,4QINW@10662|Myoviridae	10662|Myoviridae	S	Pfam:Peptidase_S77	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160870_1	656519.Halsa_1582	1.19e-58	195.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WADM@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_145970_1	1463825.JNXC01000053_gene7	8.27e-07	55.5	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4EESF@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_230359_1	1499967.BAYZ01000090_gene4959	7.77e-60	206.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2NNT2@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00162,ko:K00167,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_184206_1	221288.JH992901_gene3300	6.78e-35	138.0	COG1672@1|root,COG1672@2|Bacteria,1G4AU@1117|Cyanobacteria,1JKIX@1189|Stigonemataceae	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_29431_2	1027273.GZ77_02110	7.41e-14	67.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_Tnp_IS630
k59_68203_1	1042375.AFPL01000030_gene491	2.88e-58	201.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,1RY40@1236|Gammaproteobacteria,46ABF@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
k59_13749_1	1415778.JQMM01000001_gene2178	5.1e-80	243.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_13749_2	1288826.MSNKSG1_00536	8.78e-28	102.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_99129_1	765911.Thivi_3797	9.97e-24	98.2	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales	135613|Chromatiales	G	PFAM Fructosamine	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_99129_2	2340.JV46_06250	1.3e-60	190.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1J60R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
k59_215066_1	1165841.SULAR_09354	4.99e-31	117.0	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_215066_2	1165841.SULAR_09359	6.39e-74	226.0	COG4649@1|root,COG4649@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_145971_1	999141.GME_04667	6.97e-26	96.7	COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1XKZ6@135619|Oceanospirillales	135619|Oceanospirillales	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k59_145971_2	1190606.AJYG01000168_gene3912	2.35e-55	180.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XSNS@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	TLL0138	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_145971_3	1026882.MAMP_01030	1.23e-35	144.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,45ZUT@72273|Thiotrichales	72273|Thiotrichales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_207262_1	675814.VIC_001831	1.6e-18	85.1	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,1XT4D@135623|Vibrionales	135623|Vibrionales	P	COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_137545_1	1034769.KB910518_gene2563	9.61e-17	82.4	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,26R06@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_137545_2	1117319.PSPO_05451	4.85e-12	66.6	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,2Q07I@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
k59_176228_2	2340.JV46_18440	1.16e-34	126.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1J502@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2444	PALP
k59_215072_1	395493.BegalDRAFT_1425	7.47e-121	358.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,45ZX9@72273|Thiotrichales	72273|Thiotrichales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_191916_1	1411685.U062_02242	3.19e-05	51.6	COG2207@1|root,COG2207@2|Bacteria,1R7PM@1224|Proteobacteria,1RYYY@1236|Gammaproteobacteria,1J9FI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_191919_2	317619.ANKN01000149_gene1472	4.92e-15	78.2	COG4191@1|root,COG4191@2|Bacteria,1G5E0@1117|Cyanobacteria	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_130105_2	1333998.M2A_2347	9.34e-36	126.0	COG0640@1|root,COG0640@2|Bacteria,1N0HB@1224|Proteobacteria,2UDT7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_169044_1	71139.XP_010065334.1	1.15e-26	100.0	COG0361@1|root,2S8M9@2759|Eukaryota,37VXN@33090|Viridiplantae,3GKBP@35493|Streptophyta	35493|Streptophyta	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009507,GO:0009536,GO:0043021,GO:0043022,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_169044_2	13333.ERM96121	8.08e-84	248.0	COG0100@1|root,KOG0408@2759|Eukaryota,37UVR@33090|Viridiplantae,3GJ9B@35493|Streptophyta	35493|Streptophyta	J	Belongs to the universal ribosomal protein uS11 family	rps11	GO:0000028,GO:0000313,GO:0000314,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0031974,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070013,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0098798,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_169044_3	4155.Migut.D01434.1.p	7.42e-209	582.0	COG0202@1|root,2QRS7@2759|Eukaryota,37QVG@33090|Viridiplantae,3GHDB@35493|Streptophyta,44N87@71274|asterids	35493|Streptophyta	K	Bacterial RNA polymerase, alpha chain C terminal domain	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0031976,GO:0031984,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_169044_4	4577.GRMZM5G884960_P01	8.13e-124	352.0	COG1290@1|root,KOG4663@2759|Eukaryota,37NKU@33090|Viridiplantae,3G85T@35493|Streptophyta,3KZB0@4447|Liliopsida,3IH6E@38820|Poales	35493|Streptophyta	C	Cytochrome b6-f complex subunit 4	petD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02637	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B_C
k59_169044_5	4577.GRMZM5G800780_P01	1.44e-161	452.0	COG1290@1|root,KOG4663@2759|Eukaryota,37QS7@33090|Viridiplantae,3GHBB@35493|Streptophyta,3KUYY@4447|Liliopsida,3IBNR@38820|Poales	35493|Streptophyta	C	Cytochrome b6	petB	-	-	ko:K02635	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrome_B
k59_169044_6	50452.A0A087GI96	1.84e-41	137.0	2E1MV@1|root,2S8Y7@2759|Eukaryota,37WT7@33090|Viridiplantae,3GKK7@35493|Streptophyta	35493|Streptophyta	S	One of the components of the core complex of photosystem II (PSII), required for its stability and or assembly. PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbH	-	-	ko:K02709	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbH
k59_169044_7	59689.Al_scaffold_0002_946	0.0	899.0	28JG1@1|root,2QRV6@2759|Eukaryota,37HEX@33090|Viridiplantae,3GE8P@35493|Streptophyta,3HZ99@3699|Brassicales	35493|Streptophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_122446_1	1168034.FH5T_06490	2.99e-58	201.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NGJJ@976|Bacteroidetes,2FRXF@200643|Bacteroidia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_52492_1	3988.XP_002534684.1	1.1e-39	138.0	2E43Y@1|root,2SB2A@2759|Eukaryota,37X2E@33090|Viridiplantae,3GKUQ@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83366_1	933262.AXAM01000004_gene2398	2.99e-50	179.0	COG0457@1|root,COG0683@1|root,COG0457@2|Bacteria,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,2MHTC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
k59_122452_1	1317122.ATO12_10990	2.66e-91	295.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2YGPX@290174|Aquimarina	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_199823_1	760192.Halhy_1383	4.97e-15	76.6	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1IVN8@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_45028_1	378806.STAUR_0118	1.77e-74	251.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,438QJ@68525|delta/epsilon subdivisions,2X3XW@28221|Deltaproteobacteria,2YXIE@29|Myxococcales	28221|Deltaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
k59_21755_1	331869.BAL199_28470	1.27e-10	60.8	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2TRWV@28211|Alphaproteobacteria,4BQPA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,TAT_signal
k59_21755_2	2340.JV46_04870	1.06e-102	305.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,1RXEQ@1236|Gammaproteobacteria,1J8ZY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_45031_1	1517416.IDAT_04895	6.32e-16	75.5	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,2QG2U@267893|Idiomarinaceae	1236|Gammaproteobacteria	Q	MlaD protein	mlaD	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_45031_2	1304888.ATWF01000001_gene941	1.41e-12	67.4	COG0767@1|root,COG0767@2|Bacteria,2GEJX@200930|Deferribacteres	200930|Deferribacteres	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_238541_1	1165841.SULAR_06653	4.98e-105	314.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_161106_1	425104.Ssed_3708	4.2e-86	267.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1SM2G@1236|Gammaproteobacteria,2QAAP@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_192158_1	1195246.AGRI_12781	2.22e-60	212.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4645Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_192158_2	1165841.SULAR_08055	1.01e-21	88.6	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	MORN_2,TonB_C
k59_68389_1	592029.DDD_2283	0.000191	43.5	COG1216@1|root,COG1216@2|Bacteria,4NKPU@976|Bacteroidetes,1HX1T@117743|Flavobacteriia	976|Bacteroidetes	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_68389_2	2340.JV46_10330	8.74e-57	177.0	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,1J6TU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1244)	IV02_17390	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
k59_68389_3	2340.JV46_10320	9.33e-40	140.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1J6GX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin	ybbN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_215236_1	95619.PM1_0206355	2.28e-51	172.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_192161_1	1165841.SULAR_03342	1.73e-41	147.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_29734_1	1397528.Q671_09500	1.5e-113	335.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_29734_2	118173.KB235914_gene2071	1.29e-30	110.0	COG2963@1|root,COG2963@2|Bacteria,1GAAT@1117|Cyanobacteria,1HGRD@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_76215_2	1211112.ALJC01000140_gene2647	6.69e-33	130.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	(Type IV) pilus	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_161115_1	745411.B3C1_02970	7.42e-34	129.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1J5WC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrE	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_232985_1	2340.JV46_28920	7.55e-44	142.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SCFA@1236|Gammaproteobacteria,1J6VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k59_232985_2	292415.Tbd_0575	2.53e-49	160.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2VS0Z@28216|Betaproteobacteria,1KSU4@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_201937_1	1168034.FH5T_01025	2.25e-93	285.0	COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes	976|Bacteroidetes	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_N
k59_178810_1	1170562.Cal6303_3041	1.96e-76	244.0	COG2433@1|root,COG2433@2|Bacteria,1G93F@1117|Cyanobacteria,1HTA7@1161|Nostocales	1117|Cyanobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_85941_1	1254432.SCE1572_15570	1.22e-11	69.3	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
k59_155557_1	620914.JH621258_gene994	1.18e-08	63.9	COG1361@1|root,COG4386@1|root,COG1361@2|Bacteria,COG4386@2|Bacteria,4PNM9@976|Bacteroidetes,1IK90@117743|Flavobacteriia,2YM61@290174|Aquimarina	976|Bacteroidetes	M	tail sheath protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31880_1	1265505.ATUG01000001_gene4148	1.04e-14	73.2	2AKQ6@1|root,2ZAYQ@2|Bacteria,1R429@1224|Proteobacteria,42NWN@68525|delta/epsilon subdivisions,2WMKI@28221|Deltaproteobacteria,2MHZS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
k59_31880_2	1117644.MCANPG14_03110	6.43e-30	113.0	COG0634@1|root,COG0634@2|Bacteria,3WTD5@544448|Tenericutes	544448|Tenericutes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_163281_1	215803.DB30_3173	4.81e-25	103.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
k59_132283_1	981336.F944_02275	1.49e-74	231.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,3NKMT@468|Moraxellaceae	1236|Gammaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_16236_2	323848.Nmul_A0131	1.15e-39	140.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,371XV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_225166_1	2340.JV46_28090	2.27e-156	451.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1J4E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0348 Polyferredoxin	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_194159_1	648885.KB316283_gene3986	3.23e-38	143.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,2TVN2@28211|Alphaproteobacteria,1JQTS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	HP	MoeA domain protein domain I and II	MA20_10225	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k59_225170_2	1121396.KB893076_gene696	1.54e-31	121.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WKMQ@28221|Deltaproteobacteria,2MK2X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Phage tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_78164_1	85643.Tmz1t_0247	3.14e-08	55.1	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria,2KXF3@206389|Rhodocyclales	206389|Rhodocyclales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_78164_2	247639.MGP2080_05552	2.02e-22	91.3	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_209639_1	106648.BBLJ01000009_gene773	1.64e-17	76.6	COG2018@1|root,COG2018@2|Bacteria,1QV3M@1224|Proteobacteria,1T270@1236|Gammaproteobacteria,3NTN4@468|Moraxellaceae	1236|Gammaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109089_1	1131269.AQVV01000013_gene1719	2.12e-28	112.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	AAA_22,Epimerase_2
k59_225172_1	56780.SYN_02705	1.38e-151	430.0	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,42QAW@68525|delta/epsilon subdivisions,2WIXS@28221|Deltaproteobacteria,2MRNN@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	ATPase MipZ	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_62692_2	391625.PPSIR1_08746	5.86e-12	69.3	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
k59_186523_1	1121405.dsmv_1731	1.23e-60	201.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2MJ79@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_16245_1	525897.Dbac_1814	3.22e-19	91.3	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WMAP@28221|Deltaproteobacteria,2MGWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,Phenol_MetA_deg,TSP_3,VWA
k59_23980_1	1382359.JIAL01000001_gene1133	2.68e-08	56.6	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GJ@57723|Acidobacteria,2JJ01@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
k59_23980_2	118168.MC7420_1742	1.01e-14	73.9	COG3217@1|root,COG3217@2|Bacteria,1G41J@1117|Cyanobacteria,1HA5C@1150|Oscillatoriales	1117|Cyanobacteria	S	Fe-S protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
k59_93722_1	313596.RB2501_00081	3.16e-62	202.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1HWMA@117743|Flavobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_109104_1	247634.GPB2148_3455	2.81e-96	292.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1J4TU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Domain of unknown function (DUF3333)	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_124557_1	529507.PMI2048	3.21e-25	99.4	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,3Z144@583|Proteus	1236|Gammaproteobacteria	V	Ami_2	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K01447,ko:K03806	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560	Amidase_2
k59_124557_2	1123400.KB904769_gene2850	1.19e-44	157.0	COG4246@1|root,COG4246@2|Bacteria,1RENT@1224|Proteobacteria,1S6FR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_194170_1	1168034.FH5T_05905	3.6e-45	151.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,2FU81@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_8587_1	1121374.KB891578_gene3269	1.47e-15	81.3	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2K9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_16255_1	666685.R2APBS1_1464	6.88e-98	296.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1X2ZD@135614|Xanthomonadales	135614|Xanthomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_194175_1	1165841.SULAR_00390	2.31e-69	236.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_101406_1	2340.JV46_17540	2.97e-97	295.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1J70K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_140207_2	998674.ATTE01000001_gene3535	1.71e-29	121.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T2WX@1236|Gammaproteobacteria,462NY@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,PAS_2,PHY
k59_124564_1	1242864.D187_007260	2.36e-18	90.5	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
k59_863_1	4081.Solyc01g007340.2.1	3.33e-263	732.0	COG4799@1|root,KOG0540@2759|Eukaryota,37NPW@33090|Viridiplantae,3GG0Z@35493|Streptophyta,44QTN@71274|asterids	35493|Streptophyta	H	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963,ko:K02696	ko00061,ko00195,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00195,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Carboxyl_trans,PSI_8
k59_178838_1	1137799.GZ78_11910	4.71e-47	169.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XH6K@135619|Oceanospirillales	135619|Oceanospirillales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_55074_1	1229172.JQFA01000002_gene4655	9.53e-23	100.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
k59_201975_1	395493.BegalDRAFT_0206	6.44e-18	80.9	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,460GD@72273|Thiotrichales	72273|Thiotrichales	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k59_202284_2	1218108.KB908293_gene1165	1.19e-05	47.8	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
k59_86239_1	1168034.FH5T_05370	1.46e-63	215.0	COG4773@1|root,COG4773@2|Bacteria,4PM17@976|Bacteroidetes,2G187@200643|Bacteroidia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_233376_1	1123393.KB891316_gene1363	3.13e-12	66.6	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2W14D@28216|Betaproteobacteria,1KS2M@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Alpha amylase, C-terminal all-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_233376_2	2340.JV46_06580	2.37e-228	640.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1J895@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_78489_1	59538.XP_005973179.1	2.18e-16	77.4	COG0197@1|root,KOG3422@2759|Eukaryota,39S31@33154|Opisthokonta,3BPN3@33208|Metazoa	33208|Metazoa	J	Ribosomal protein S3, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	KH_2,Ribosomal_S3_C
k59_78489_2	272621.LBA0299	3.4e-06	47.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_78489_3	1454202.PPBDW_80327___1	1.19e-36	125.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XXXG@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_78489_4	765914.ThisiDRAFT_1678	1.37e-72	219.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1WY84@135613|Chromatiales	135613|Chromatiales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_78489_5	1123367.C666_00440	1.58e-08	52.4	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,2KWPF@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_94060_1	269799.Gmet_2924	7.32e-12	70.9	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P5K@68525|delta/epsilon subdivisions,2WMEF@28221|Deltaproteobacteria,43TIX@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_101687_1	2340.JV46_27230	1.08e-46	162.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1J4Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_55321_1	1123234.AUKI01000011_gene1419	6.16e-50	186.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_8957_1	1165841.SULAR_08909	2.09e-129	397.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_194499_1	1123008.KB905692_gene417	2.12e-21	93.6	2DSTI@1|root,33HD4@2|Bacteria,4NYHV@976|Bacteroidetes,2FZJE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_186780_1	1121004.ATVC01000051_gene1783	2.63e-64	209.0	COG2270@1|root,COG2270@2|Bacteria,1QUVA@1224|Proteobacteria,2WHTQ@28216|Betaproteobacteria,2KU4X@206351|Neisseriales	206351|Neisseriales	S	AmpG muropeptide MFS transporter K08218	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_186780_2	640511.BC1002_0047	3.59e-61	194.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,1K01S@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Exodeoxyribonuclease III	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_240843_1	754476.Q7A_709	1.75e-73	245.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,461TW@72273|Thiotrichales	72273|Thiotrichales	M	Phosphoglycerol transferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_132612_1	1117108.PAALTS15_28791	6.81e-22	102.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	nrsA	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Aminotran_3,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_94062_1	251229.Chro_2010	9.62e-36	128.0	28JCT@1|root,2Z97C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_127009_1	1415756.JQMY01000001_gene2149	5.45e-47	162.0	COG2169@1|root,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.1.31.1,3.2.2.21	ko:K01174,ko:K07720,ko:K13529,ko:K15051	ko02020,ko03410,map02020,map03410	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko03000,ko03400	-	-	-	Ada_Zn_binding,AraC_N,DNA_binding_1,Endonuclea_NS_2,HTH_18,PocR
k59_235303_1	631362.Thi970DRAFT_03279	3.95e-52	186.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1WXT3@135613|Chromatiales	135613|Chromatiales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_181150_1	903818.KI912268_gene1496	9.76e-81	270.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_10951_1	98439.AJLL01000090_gene133	3.99e-50	182.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JJEC@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_157798_1	862908.BMS_2527	1.38e-15	82.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2MT59@213481|Bdellovibrionales,2WKBG@28221|Deltaproteobacteria	213481|Bdellovibrionales	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
k59_119246_1	313590.MED134_01065	2.63e-22	94.7	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1HXDR@117743|Flavobacteriia,37E7Q@326319|Dokdonia	976|Bacteroidetes	F	MGS-like domain	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_119246_2	313596.RB2501_08940	5.63e-84	256.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia	976|Bacteroidetes	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_111409_1	225937.HP15_1807	3.17e-46	167.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,465WW@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	yejA	GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042597,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k59_134517_1	999541.bgla_2g16930	2.27e-36	141.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	orbJ	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_64966_1	1210884.HG799462_gene8991	9.85e-96	291.0	COG1413@1|root,COG1413@2|Bacteria,2IX4C@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
k59_142419_1	105559.Nwat_2821	2.16e-130	400.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,1WXID@135613|Chromatiales	135613|Chromatiales	S	doubled CXXCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_19,TPR_8
k59_188795_1	1537994.JQFW01000031_gene1049	9.72e-92	293.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,1RPC7@1236|Gammaproteobacteria,465QW@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_34295_1	933262.AXAM01000016_gene182	3e-65	213.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MHTP@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_188797_1	765913.ThidrDRAFT_0850	5.53e-45	164.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1WXUR@135613|Chromatiales	135613|Chromatiales	P	PFAM Na Picotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k59_127031_1	1123401.JHYQ01000016_gene3039	1.76e-39	140.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0524 Sugar kinases, ribokinase family	gsk	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.15,2.7.1.4,2.7.1.73	ko:K00847,ko:K00852,ko:K00892	ko00030,ko00051,ko00230,ko00500,ko00520,ko01100,map00030,map00051,map00230,map00500,map00520,map01100	-	R00760,R00867,R01051,R01131,R01228,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSDY_1059.SDY_0442	PfkB
k59_127031_2	1123514.KB905899_gene1278	6.63e-63	216.0	COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria,1MWF8@1224|Proteobacteria,1RPJ6@1236|Gammaproteobacteria,461I8@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
k59_26280_1	2340.JV46_17720	2.51e-138	402.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1J56Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_119257_1	57918.XP_004309313.1	2.29e-104	303.0	COG0090@1|root,KOG0438@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,4JTF7@91835|fabids	35493|Streptophyta	J	50S ribosomal protein	rpl2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C,Ribosomal_S19
k59_119257_2	3712.Bo1g034570.1	4.89e-82	258.0	COG0090@1|root,KOG0438@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,3I1MH@3699|Brassicales	35493|Streptophyta	J	Ribosomal Proteins L2, C-terminal domain	rpl2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C,Ribosomal_S19
k59_119257_3	29760.VIT_03s0038g02780.t01	6.18e-60	184.0	COG0089@1|root,2S1Z9@2759|Eukaryota,37VSJ@33090|Viridiplantae,3GJY5@35493|Streptophyta	35493|Streptophyta	J	ribosomal protein L23	rpl23	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_134527_1	1165841.SULAR_04412	2.37e-117	343.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42Q58@68525|delta/epsilon subdivisions,2YNDQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_64981_1	396588.Tgr7_0578	2.51e-91	285.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1WW0Q@135613|Chromatiales	135613|Chromatiales	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_119268_1	649349.Lbys_0273	2.46e-47	165.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,47PFY@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the glycosyl hydrolase 13 family	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
k59_111421_1	1148.1653268	2.75e-86	279.0	COG0847@1|root,COG1474@1|root,COG0847@2|Bacteria,COG1474@2|Bacteria,1G1X6@1117|Cyanobacteria,1H5ZE@1142|Synechocystis	1117|Cyanobacteria	LO	EXOIII	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
k59_18354_1	1333507.AUTQ01000179_gene1828	4.59e-05	46.6	COG0664@1|root,COG0664@2|Bacteria,1QU34@1224|Proteobacteria,1T2BY@1236|Gammaproteobacteria,2Q0SS@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
k59_18354_2	522306.CAP2UW1_0183	2.37e-26	103.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,1KQ05@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	General function prediction only	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_88145_1	1165841.SULAR_02073	3.02e-95	283.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_88145_2	1165841.SULAR_02068	2.57e-164	464.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2YNC5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_166115_2	1168034.FH5T_19620	1.51e-34	118.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,2FUKE@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_189170_1	472759.Nhal_4003	3.68e-52	171.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria,1WWIN@135613|Chromatiales	135613|Chromatiales	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_158226_1	1122134.KB893650_gene1288	1.51e-56	183.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_96353_1	1163617.SCD_n02189	1.45e-23	100.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2VPWB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2
k59_127437_1	338963.Pcar_0577	1.11e-106	324.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria,43W2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_111965_1	1123518.ARWI01000001_gene826	3.26e-84	260.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,45ZWD@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_42239_1	395493.BegalDRAFT_0199	8.74e-14	71.6	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,4604V@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_42239_2	870187.Thini_1819	1.9e-31	121.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,4628N@72273|Thiotrichales	72273|Thiotrichales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
k59_88556_1	2340.JV46_05590	9.49e-36	126.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1J6VX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	RnfH family Ubiquitin	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
k59_88556_2	1026882.MAMP_00292	3.07e-08	55.5	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,460P1@72273|Thiotrichales	72273|Thiotrichales	FP	Belongs to the GppA Ppx family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_119677_1	1288826.MSNKSG1_08918	5.34e-06	50.1	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,4645D@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Protein of unknown function (DUF1302)	aidA	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_119677_2	2340.JV46_08630	4.48e-74	230.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1J4PH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9,4.3.1.9	ko:K00384,ko:K22345	ko00030,ko00450,map00030,map00450	-	R01544,R02016,R03596,R09372	RC00013,RC00544,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_34636_1	1168034.FH5T_06235	7.02e-37	133.0	COG3386@1|root,COG3386@2|Bacteria,4PKGZ@976|Bacteroidetes	976|Bacteroidetes	G	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34636_2	742767.HMPREF9456_01054	8.3e-25	99.4	COG1670@1|root,COG1670@2|Bacteria,4NQ4Z@976|Bacteroidetes,2FSTX@200643|Bacteroidia,22YCY@171551|Porphyromonadaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
k59_135017_1	1379270.AUXF01000003_gene3758	1.15e-07	52.4	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_135017_2	1150621.SMUL_2491	4.71e-105	314.0	COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,42R32@68525|delta/epsilon subdivisions,2YNVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
k59_181548_1	126957.SMAR002271-PA	1.38e-41	160.0	COG0261@1|root,COG1748@1|root,KOG1009@1|root,KOG0172@2759|Eukaryota,KOG1009@2759|Eukaryota,KOG1686@2759|Eukaryota,38BKM@33154|Opisthokonta,3BDVH@33208|Metazoa,3CSBS@33213|Bilateria,41V08@6656|Arthropoda	33208|Metazoa	E	Oxidoreductase activity. It is involved in the biological process described with oxidation-reduction process	AASS	GO:0003674,GO:0003824,GO:0004753,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009067,GO:0009068,GO:0009085,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0019477,GO:0019752,GO:0019878,GO:0022607,GO:0031974,GO:0042737,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046395,GO:0046440,GO:0047130,GO:0047131,GO:0051259,GO:0051262,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	1.5.1.8,1.5.1.9	ko:K14157	ko00310,ko01100,ko01110,ko01130,map00310,map01100,map01110,map01130	M00032	R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,Sacchrp_dh_C,Sacchrp_dh_NADP
k59_142919_1	1335757.SPICUR_05145	2.41e-15	78.6	COG1794@1|root,COG1794@2|Bacteria,1QEFX@1224|Proteobacteria,1S0ER@1236|Gammaproteobacteria,1WZJN@135613|Chromatiales	135613|Chromatiales	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_227786_1	1121904.ARBP01000009_gene4391	1.06e-25	110.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NTWA@976|Bacteroidetes,47RKM@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_135019_1	1165841.SULAR_09374	3.18e-107	320.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_197108_1	1267535.KB906767_gene4691	1.81e-14	70.1	COG0822@1|root,COG0822@2|Bacteria,3Y55Q@57723|Acidobacteria	57723|Acidobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
k59_197108_2	1449076.JOOE01000003_gene3207	3.65e-33	120.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2K4IC@204457|Sphingomonadales	204457|Sphingomonadales	S	FeS assembly SUF system protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
k59_197108_3	99598.Cal7507_3801	4.89e-53	182.0	COG0489@1|root,COG0489@2|Bacteria,1G1I7@1117|Cyanobacteria,1HJRE@1161|Nostocales	1117|Cyanobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_111973_1	102107.XP_008245779.1	1.01e-146	424.0	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta,4JS2T@91835|fabids	35493|Streptophyta	C	Ribulose bisphosphate carboxylase, large chain	rbcL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.1.3.15,4.1.1.39,6.4.1.2	ko:K01601,ko:K01963	ko00061,ko00620,ko00630,ko00640,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00630,map00640,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00165,M00166,M00376,M00532	R00024,R00742,R03140,R04386	RC00040,RC00172,RC00253,RC00367,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_65367_1	1165841.SULAR_06423	9.87e-110	322.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2YMK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_135020_1	572480.Arnit_1227	8.36e-43	150.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2YNCJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_135020_2	572480.Arnit_1226	1.45e-28	112.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2YNPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Abc transporter, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_119686_1	1165841.SULAR_05903	7.35e-101	293.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42QQM@68525|delta/epsilon subdivisions,2YNZA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	signal transduction sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_96374_1	1123401.JHYQ01000006_gene58	2.19e-99	296.0	COG1305@1|root,COG1305@2|Bacteria,1MVAG@1224|Proteobacteria,1RMXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_212434_1	396588.Tgr7_2456	2.87e-75	249.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_212434_2	1002672.SAR11G3_00622	2.44e-09	57.8	COG0508@1|root,COG2609@1|root,COG0508@2|Bacteria,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,4BQKZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transketolase_N
k59_162152_1	234267.Acid_1957	1.81e-20	95.5	COG0457@1|root,COG0760@1|root,COG0457@2|Bacteria,COG0760@2|Bacteria,3Y67U@57723|Acidobacteria	57723|Acidobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_201069_1	1177179.A11A3_07950	1.44e-06	55.5	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,1RP3Z@1236|Gammaproteobacteria,1XNKU@135619|Oceanospirillales	135619|Oceanospirillales	CH	FAD binding domain	-	-	1.14.13.113	ko:K16839	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R09514	RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_208567_1	2340.JV46_23640	1.07e-78	262.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_92383_2	926559.JoomaDRAFT_2458	3.33e-29	121.0	COG0400@1|root,COG0400@2|Bacteria,4NJ8E@976|Bacteroidetes,1HXED@117743|Flavobacteriia	976|Bacteroidetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_231531_2	1410608.JNKX01000063_gene2599	6.93e-08	57.0	COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,2FWGT@200643|Bacteroidia,4AV2U@815|Bacteroidaceae	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
k59_46134_1	1168034.FH5T_05005	1.49e-86	260.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,2FMTY@200643|Bacteroidia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
k59_216229_1	1123236.KB899399_gene3307	4.08e-09	61.2	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_7588_1	945713.IALB_1680	1.99e-27	111.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_7588_2	523791.Kkor_1147	4.33e-112	338.0	COG0686@1|root,COG0686@2|Bacteria,1MXDG@1224|Proteobacteria,1RSMS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_22882_1	631362.Thi970DRAFT_04985	6.72e-84	266.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1R97Q@1224|Proteobacteria,1RRDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_201085_1	1165841.SULAR_00140	1.86e-76	236.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_162165_1	519989.ECTPHS_11532	4.51e-21	85.9	2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,1S7UG@1236|Gammaproteobacteria,1WY6X@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162165_2	1211115.ALIQ01000180_gene1548	1.33e-09	61.2	COG2979@1|root,COG2979@2|Bacteria,1R95E@1224|Proteobacteria,2U3YT@28211|Alphaproteobacteria,3NCM2@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF533)	-	-	-	-	-	-	-	-	-	-	-	-	DUF533
k59_69426_1	1541065.JRFE01000014_gene1436	5.1e-16	80.1	COG3210@1|root,COG3210@2|Bacteria,1G0EK@1117|Cyanobacteria,3VJDT@52604|Pleurocapsales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
k59_92401_1	795666.MW7_1638	2e-39	149.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,2VHP6@28216|Betaproteobacteria,1KIJD@119060|Burkholderiaceae	28216|Betaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_7596_3	870187.Thini_4318	9.47e-47	171.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZNC@72273|Thiotrichales	1236|Gammaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_14973_1	384765.SIAM614_17224	1.07e-77	247.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0433 Predicted ATPase	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_84664_1	2340.JV46_05980	1.19e-76	238.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1J4TG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040	CPSase_sm_chain,GATase
k59_84664_2	2340.JV46_05970	5.43e-32	113.0	COG2841@1|root,COG2841@2|Bacteria,1PJVG@1224|Proteobacteria,1TB3F@1236|Gammaproteobacteria,1JBHY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
k59_84664_3	1380380.JIAX01000010_gene130	1.5e-33	127.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_92404_2	519989.ECTPHS_04935	7.19e-17	84.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales	135613|Chromatiales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_7601_1	1141106.CAIB01000182_gene1788	4.34e-21	92.0	COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,4HC2H@91061|Bacilli,4GZUE@90964|Staphylococcaceae	91061|Bacilli	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_193201_1	649638.Trad_2690	6.74e-68	215.0	COG4947@1|root,COG4947@2|Bacteria,1WMMQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
k59_231540_1	318586.Pden_3333	4.04e-52	167.0	COG0309@1|root,COG0309@2|Bacteria,1RDJ4@1224|Proteobacteria,2U7HE@28211|Alphaproteobacteria,2PX0J@265|Paracoccus	28211|Alphaproteobacteria	O	Transposase, IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k59_231540_2	318586.Pden_2059	2.7e-75	225.0	COG3293@1|root,COG3293@2|Bacteria,1RDDI@1224|Proteobacteria,2U7E3@28211|Alphaproteobacteria,2PX6M@265|Paracoccus	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k59_208604_1	298386.PBPRA0168	1.9e-44	158.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XU9F@135623|Vibrionales	135623|Vibrionales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_208604_2	94122.Shewana3_3991	5.52e-13	68.2	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,2Q8ZR@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_100465_1	1123228.AUIH01000131_gene2866	2.58e-90	282.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1XS1N@135619|Oceanospirillales	135619|Oceanospirillales	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_7610_1	1168034.FH5T_09635	1.9e-187	527.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_61655_1	472759.Nhal_0504	1.24e-64	206.0	COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,1WWFX@135613|Chromatiales	135613|Chromatiales	G	PFAM PfkB domain protein	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB
k59_185943_1	29730.Gorai.001G163400.1	4.36e-48	168.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,3GBUN@35493|Streptophyta	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k59_31296_1	472759.Nhal_0020	2.07e-21	89.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1WY2E@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM DJ-1 family protein	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_31296_2	527002.yaldo0001_39810	1.01e-22	100.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,41E8W@629|Yersinia	1236|Gammaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_240073_1	930166.CD58_17565	3.15e-10	62.4	COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
k59_240073_2	1265503.KB905170_gene88	1.55e-29	115.0	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,2Q5X6@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_170480_2	287.DR97_1887	1.39e-10	63.5	COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,1RNGH@1236|Gammaproteobacteria,1YFSM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_170481_1	1165841.SULAR_02668	4.01e-117	342.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_240077_1	313596.RB2501_14859	3.08e-97	311.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_147216_1	713586.KB900536_gene534	5.53e-44	162.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria,1SWBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
k59_131790_1	626523.GCWU000342_01793	6.18e-05	46.6	28JJK@1|root,2Z9CJ@2|Bacteria,1UYK6@1239|Firmicutes,24B2Y@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62154_1	234267.Acid_1602	3.01e-54	184.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
k59_62154_2	1293047.CBMA010000042_gene2620	4.25e-15	79.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23SIE@183963|Halobacteria	183963|Halobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_240080_1	1165841.SULAR_08622	2.99e-22	93.2	2A9R8@1|root,30YYK@2|Bacteria,1PKV5@1224|Proteobacteria,42XYU@68525|delta/epsilon subdivisions,2YQWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_240080_2	1165841.SULAR_08617	1.1e-58	191.0	COG0506@1|root,COG0506@2|Bacteria,1Q2W5@1224|Proteobacteria,42WCB@68525|delta/epsilon subdivisions,2YQK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	proline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31313_1	1249997.JHZW01000002_gene1361	1.23e-12	66.6	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia,2PH6I@252356|Maribacter	976|Bacteroidetes	J	Anticodon binding domain	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_31313_2	313596.RB2501_07920	5.94e-74	230.0	2DPRW@1|root,3334N@2|Bacteria,4NJ3S@976|Bacteroidetes,1HZ3B@117743|Flavobacteriia	976|Bacteroidetes	J	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_285_1	765912.Thimo_1331	3.73e-21	88.6	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1WY8B@135613|Chromatiales	135613|Chromatiales	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_285_2	1165841.SULAR_07355	3.07e-42	150.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_77572_1	199310.c4012	1.39e-133	391.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,3XP5G@561|Escherichia	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iSF_1195.SF3294	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_286_1	203124.Tery_4454	4.11e-38	147.0	COG1672@1|root,COG1672@2|Bacteria,1G2YT@1117|Cyanobacteria,1H8BR@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,ATPase_2,HTH_IclR
k59_185956_1	1397528.Q671_12935	8.91e-33	117.0	COG4541@1|root,COG4541@2|Bacteria,1MZK0@1224|Proteobacteria,1T04Q@1236|Gammaproteobacteria,1XRPI@135619|Oceanospirillales	135619|Oceanospirillales	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
k59_185956_2	1219065.VPR01S_06_01880	6.19e-19	83.6	COG1296@1|root,COG1296@2|Bacteria,1Q43G@1224|Proteobacteria,1RPZB@1236|Gammaproteobacteria,1XWAV@135623|Vibrionales	135623|Vibrionales	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k59_240086_1	375286.mma_3197	1.7e-65	211.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,2VID4@28216|Betaproteobacteria,473BR@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_123942_1	159087.Daro_1705	2.92e-56	190.0	COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,2VNBE@28216|Betaproteobacteria,2KYM9@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_54430_1	439235.Dalk_3877	1.52e-64	201.0	COG1846@1|root,COG1846@2|Bacteria,1RM3A@1224|Proteobacteria,42SQ5@68525|delta/epsilon subdivisions,2WP5R@28221|Deltaproteobacteria,2MM60@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_185960_1	748247.AZKH_4396	4.78e-17	87.8	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,2KUCW@206389|Rhodocyclales	206389|Rhodocyclales	E	Leucine-specific binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_31328_1	984262.SGRA_2683	9.59e-12	63.9	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1INST@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_31328_2	1168034.FH5T_09515	6.06e-38	132.0	COG0566@1|root,COG0566@2|Bacteria,4PBC5@976|Bacteroidetes,2FYUB@200643|Bacteroidia	976|Bacteroidetes	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_15708_1	1165841.SULAR_06843	1.83e-64	204.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2YMHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_15708_2	1165841.SULAR_06838	2.6e-35	133.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_100849_2	1165841.SULAR_07725	1.13e-46	159.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2YN3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0663	Chorismate_synt
k59_162679_1	395493.BegalDRAFT_1683	5.08e-57	192.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,45ZQZ@72273|Thiotrichales	72273|Thiotrichales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
k59_147236_1	376686.Fjoh_1932	7.16e-80	250.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2NTJW@237|Flavobacterium	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_193659_1	192952.MM_3328	6.59e-40	140.0	COG0518@1|root,arCOG00090@2157|Archaea,2XTYN@28890|Euryarchaeota,2N9MH@224756|Methanomicrobia	224756|Methanomicrobia	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
k59_232386_1	478749.BRYFOR_09684	2.34e-23	104.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1V7Y2@1239|Firmicutes,25DHV@186801|Clostridia	186801|Clostridia	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k59_240095_1	1165841.SULAR_05363	5.89e-56	186.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2YMAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_95470_4	395493.BegalDRAFT_1817	7.34e-68	219.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_48910_1	243365.CV_2768	9.96e-46	157.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,2KPMB@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_48910_2	1336245.JAGO01000012_gene1720	1.67e-10	61.2	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XH6T@135619|Oceanospirillales	135619|Oceanospirillales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_33786_1	744979.R2A130_3316	0.000125	53.1	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,2TX0D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Rhs Family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56625_1	2340.JV46_12380	9.01e-79	261.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J4MB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_118683_1	1249627.D779_0407	9.54e-110	328.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1WVX6@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_118683_2	384676.PSEEN4199	1.03e-22	90.9	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k59_80001_1	1123326.JFBL01000001_gene1453	3.19e-13	65.5	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2YPT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_80001_2	1254432.SCE1572_26670	2.86e-41	153.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_157242_1	313596.RB2501_06795	8.39e-101	303.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1HXGT@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_95472_1	1165841.SULAR_05528	4.31e-05	43.1	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,42THN@68525|delta/epsilon subdivisions,2YPTV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
k59_95472_2	1165841.SULAR_05533	5.25e-109	325.0	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_165169_1	240016.ABIZ01000001_gene557	1.28e-24	101.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_72131_1	983548.Krodi_0344	2.02e-72	234.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia,37DPE@326319|Dokdonia	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_80011_2	118161.KB235922_gene4379	1.73e-70	216.0	COG3335@1|root,COG3335@2|Bacteria,1G5I5@1117|Cyanobacteria,3VMRJ@52604|Pleurocapsales	1117|Cyanobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_80011_3	118168.MC7420_63	1.89e-75	231.0	COG3335@1|root,COG3335@2|Bacteria,1G4FA@1117|Cyanobacteria,1HBRR@1150|Oscillatoriales	1117|Cyanobacteria	L	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_87614_1	1121403.AUCV01000038_gene4227	1.87e-106	320.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,42NDR@68525|delta/epsilon subdivisions,2WJQ4@28221|Deltaproteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_72133_1	1283340.Q6WI78_BPKVM	1.4e-19	100.0	4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses  no RNA stage,4QPYH@28883|Caudovirales,4QIYN@10662|Myoviridae	10662|Myoviridae	S	exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_172763_1	2340.JV46_17620	9.16e-53	183.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1J572@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Oligopeptidase A	prlC	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_41378_1	1168034.FH5T_21890	4.55e-42	151.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia	976|Bacteroidetes	C	2-oxoacid acceptor oxidoreductase, alpha subunit	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_41378_2	1218108.KB908300_gene2526	1.08e-40	138.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_242411_1	63737.Npun_R3027	1.57e-28	118.0	COG0001@1|root,COG0318@1|root,COG1020@1|root,COG3321@1|root,COG0001@2|Bacteria,COG0318@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HIST@1161|Nostocales	1117|Cyanobacteria	Q	acyl transferase domain	-	-	-	ko:K16129	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Bac_luciferase,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,ketoacyl-synt
k59_188635_2	1158762.KB898041_gene1329	5.87e-46	153.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1WX78@135613|Chromatiales	135613|Chromatiales	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
k59_111270_1	1379270.AUXF01000001_gene2155	1.91e-55	195.0	COG1506@1|root,COG1506@2|Bacteria,1ZUC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
k59_242763_1	641107.CDLVIII_5154	4.83e-21	90.1	COG1669@1|root,COG1669@2|Bacteria,1VBHH@1239|Firmicutes,24JZE@186801|Clostridia,36JH2@31979|Clostridiaceae	186801|Clostridia	S	DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k59_242763_2	671143.DAMO_2201	0.000225	42.7	COG2445@1|root,COG2445@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
k59_196506_1	713586.KB900536_gene1480	9.31e-90	278.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales	135613|Chromatiales	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_3110_1	1121875.KB907551_gene1069	1.16e-64	206.0	COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,1HYBV@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
k59_3110_2	313596.RB2501_06830	2.09e-52	177.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_111271_1	1356854.N007_03635	5.8e-18	85.9	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,2780D@186823|Alicyclobacillaceae	91061|Bacilli	J	FtsJ-like methyltransferase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_204105_1	313596.RB2501_07800	2.54e-50	177.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_204105_2	1121012.AUKX01000002_gene3369	1.01e-72	219.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia,23H8Q@178469|Arenibacter	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
k59_103433_1	519989.ECTPHS_13058	4.38e-107	313.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1WVZS@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_111272_1	330214.NIDE4248	7.59e-52	177.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_26140_1	1165841.SULAR_05723	3.67e-81	244.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_188644_1	395493.BegalDRAFT_1963	2.86e-35	137.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
k59_95831_1	1165841.SULAR_01090	7.3e-49	155.0	COG1144@1|root,COG1144@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	forE	-	1.2.7.1	ko:K00171,ko:K00172,ko:K02573,ko:K13795,ko:K18930	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4,Fer4_21,Fer4_4,Fer4_7,POR
k59_95831_2	1165841.SULAR_01095	2.27e-126	360.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	CO_dh,PBP_like_2
k59_95831_3	1165841.SULAR_01100	2.3e-33	124.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_34172_2	1068978.AMETH_5751	3.59e-09	57.4	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4DZDR@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_111276_1	2340.JV46_07480	2.04e-08	55.8	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1J7IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_87999_1	1366050.N234_36085	1.17e-116	348.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32
k59_111279_1	395493.BegalDRAFT_3556	7.02e-32	119.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,460FJ@72273|Thiotrichales	72273|Thiotrichales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k59_173150_1	1168034.FH5T_18890	1.02e-80	253.0	COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,2FWGT@200643|Bacteroidia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	Peptidase_M56,TonB_C
k59_72492_1	272134.KB731325_gene631	2.37e-29	118.0	COG3385@1|root,COG3385@2|Bacteria,1G2NV@1117|Cyanobacteria,1HEUG@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1,DDE_Tnp_2
k59_173152_2	207559.Dde_2500	1.28e-18	77.4	COG1813@1|root,COG1813@2|Bacteria,1N9TB@1224|Proteobacteria,42WF0@68525|delta/epsilon subdivisions,2WRSW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_3124_1	557598.LHK_03094	9.86e-31	122.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,2KQN6@206351|Neisseriales	206351|Neisseriales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_34187_1	1163617.SCD_n01203	8.85e-30	109.0	2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,2VR76@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34187_2	1123368.AUIS01000019_gene1224	6.43e-34	129.0	COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1R3QQ@1224|Proteobacteria,1RPFS@1236|Gammaproteobacteria,2NC05@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k59_41701_1	485915.Dret_1751	2.99e-70	227.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria,2MEJK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM TraB determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
k59_88008_1	2340.JV46_27740	1.99e-80	250.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,1JB8I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_88008_2	977880.RALTA_A2314	3.56e-45	152.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1K3IX@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_103454_2	1168034.FH5T_21010	1.14e-99	295.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,2FNHW@200643|Bacteroidia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
k59_126892_1	313596.RB2501_03075	4.92e-46	154.0	COG2859@1|root,COG2859@2|Bacteria,4NI76@976|Bacteroidetes,1HZJF@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
k59_126892_2	886377.Murru_1973	1.05e-29	113.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia	976|Bacteroidetes	V	Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_211827_1	172088.AUGA01000034_gene5061	8.27e-73	246.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,3JVKY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	TrkA-C domain	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_10844_1	387093.SUN_1511	8.52e-127	379.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42YPX@68525|delta/epsilon subdivisions,2YRHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_142296_1	387093.SUN_1685	2.78e-119	351.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2YMAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_196533_1	1121878.AUGL01000005_gene2690	6.11e-41	150.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_49310_1	626887.J057_23470	1.74e-71	232.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,464RX@72275|Alteromonadaceae	1236|Gammaproteobacteria	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C,RLAN,RimK
k59_227220_1	1165841.SULAR_07680	1.25e-91	280.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2YMC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_10851_1	1286632.P278_25020	4.22e-87	267.0	COG0477@1|root,COG2814@2|Bacteria,4PKJD@976|Bacteroidetes,1IJAV@117743|Flavobacteriia	976|Bacteroidetes	EGP	Nucleoside H symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
k59_235227_1	857087.Metme_1294	3.95e-71	229.0	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,1T5BK@1236|Gammaproteobacteria,1XG3Z@135618|Methylococcales	135618|Methylococcales	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_21497_1	1168034.FH5T_01510	5.58e-94	304.0	COG0577@1|root,COG0577@2|Bacteria,4NZYZ@976|Bacteroidetes,2FWFC@200643|Bacteroidia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_199742_1	349521.HCH_03648	1.91e-75	246.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,1XMXM@135619|Oceanospirillales	135619|Oceanospirillales	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
k59_145925_1	400682.PAC_15727944	6.83e-54	176.0	COG0317@1|root,KOG1157@2759|Eukaryota,39Y6C@33154|Opisthokonta,3BNBB@33208|Metazoa	33208|Metazoa	T	guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	HDDC3	GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008893,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009154,GO:0009164,GO:0009166,GO:0009259,GO:0009261,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0015971,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0031667,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034035,GO:0034037,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.7.2	ko:K21138	ko00230,map00230	-	R00336	RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
k59_99089_2	1250232.JQNJ01000001_gene755	4.93e-40	145.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1HYGI@117743|Flavobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_106534_1	1123399.AQVE01000042_gene1326	1.36e-15	72.8	COG0454@1|root,COG0454@2|Bacteria,1QUS5@1224|Proteobacteria,1RRHY@1236|Gammaproteobacteria,4630T@72273|Thiotrichales	72273|Thiotrichales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_52449_1	472759.Nhal_3492	9.39e-67	216.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WW9C@135613|Chromatiales	135613|Chromatiales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_52449_2	1184609.KILIM_024_00550	4.77e-08	54.7	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4F6Q3@85018|Dermatophilaceae	201174|Actinobacteria	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_13688_1	397945.Aave_3355	1.45e-144	436.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VMB0@28216|Betaproteobacteria,4ABB8@80864|Comamonadaceae	28216|Betaproteobacteria	L	Type I restriction enzyme R protein N terminus (HSDR_N)	hsdR-1	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,ResIII
k59_106535_1	1168034.FH5T_05050	9.21e-88	271.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,2FM6X@200643|Bacteroidia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_106535_2	1168034.FH5T_05055	3.45e-26	104.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,2FKYH@200643|Bacteroidia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_137520_1	351348.Maqu_1858	6.43e-52	170.0	COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,466MT@72275|Alteromonadaceae	1236|Gammaproteobacteria	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
k59_145936_1	648885.KB316282_gene346	1.3e-47	171.0	COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1MV41@1224|Proteobacteria,2TQXP@28211|Alphaproteobacteria,1JZHZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	ko:K02613,ko:K07006	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,Putative_PNPOx
k59_21520_1	1168067.JAGP01000001_gene534	1.07e-92	283.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,460U9@72273|Thiotrichales	72273|Thiotrichales	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_153042_1	2340.JV46_22080	1.69e-22	91.7	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1J5QJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA	rlmG	-	2.1.1.174	ko:K11391	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
k59_153042_2	1049564.TevJSym_as00740	2.16e-37	129.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,1S5H3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114407_1	1117647.M5M_07440	8.59e-18	86.7	COG1226@1|root,32Y28@2|Bacteria,1PVKC@1224|Proteobacteria,1T8P4@1236|Gammaproteobacteria,1JBD0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1226 Kef-type K transport systems	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
k59_114407_2	1122132.AQYH01000007_gene2179	8.26e-25	100.0	2DS4T@1|root,32USD@2|Bacteria,1RIFI@1224|Proteobacteria,2UBWM@28211|Alphaproteobacteria,4B97C@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114407_3	864069.MicloDRAFT_00018980	2.09e-59	199.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2TTW3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	multi-drug resistance efflux pump	yiaV	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
k59_238267_1	598659.NAMH_0970	4.1e-142	421.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_184175_1	502025.Hoch_2529	3.36e-54	192.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_137828_1	395493.BegalDRAFT_0882	9.61e-38	141.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,1RSJ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
k59_91462_2	768671.ThimaDRAFT_3543	4.92e-16	76.3	2DS06@1|root,33DXP@2|Bacteria,1NJMQ@1224|Proteobacteria,1SJ5T@1236|Gammaproteobacteria,1X288@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146235_1	1165841.SULAR_00840	1.68e-107	319.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_137830_1	1165841.SULAR_02523	4.31e-53	175.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,42VS9@68525|delta/epsilon subdivisions,2YQD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Cytochrome c family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_14008_2	387093.SUN_0512	1.67e-56	187.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1N7HT@1224|Proteobacteria,42RFF@68525|delta/epsilon subdivisions,2YP9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_207532_1	1217652.F954_00056	8.21e-07	54.3	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,3NKB9@468|Moraxellaceae	1236|Gammaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,He_PIG,HemolysinCabind
k59_137835_1	1117318.PRUB_10572	9.26e-30	122.0	COG1409@1|root,COG1409@2|Bacteria,1R8W7@1224|Proteobacteria,1SSD6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_14013_1	439375.Oant_4267	7.44e-54	181.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,1J1WK@118882|Brucellaceae	28211|Alphaproteobacteria	O	prohibitin homologues	qmcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k59_99425_1	313596.RB2501_08285	4.34e-95	285.0	COG0810@1|root,COG0810@2|Bacteria,4NN8A@976|Bacteroidetes,1I18J@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14016_1	980584.AFPB01000122_gene2440	1.09e-19	85.1	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1I28E@117743|Flavobacteriia,406I1@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	C	ATP synthase delta (OSCP) subunit	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_14016_2	1250232.JQNJ01000001_gene1314	7.01e-55	185.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_207548_1	1165841.SULAR_01035	2.39e-53	186.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	2|Bacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_29785_1	1537994.JQFW01000002_gene3422	2.61e-44	155.0	COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,464GV@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Lipopolysaccharide biosynthesis protein	walW	-	-	-	-	-	-	-	-	-	-	-	-
k59_246235_1	1168034.FH5T_04420	5.58e-120	347.0	COG0024@1|root,COG0024@2|Bacteria,4NIMB@976|Bacteroidetes,2FM2H@200643|Bacteroidia	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_60583_1	1165841.SULAR_00380	2.36e-62	199.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2YMRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_37649_2	7668.SPU_001651-tr	1.38e-71	243.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_184535_1	1165841.SULAR_09399	1.21e-121	367.0	COG1262@1|root,COG1352@1|root,COG1262@2|Bacteria,COG1352@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_21836_1	765912.Thimo_2751	1.47e-15	73.2	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1WZDQ@135613|Chromatiales	135613|Chromatiales	S	NTP binding protein (Contains STAS domain)	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
k59_21836_2	2340.JV46_17700	7.05e-12	63.5	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1J6Q7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	MlaC protein	mlaC	GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0015711,GO:0015748,GO:0015914,GO:0016043,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009,GO:0120010	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_52771_1	2340.JV46_24830	7.28e-134	386.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1J4QF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_6567_1	717606.PaecuDRAFT_0042	4.76e-05	52.0	COG1404@1|root,COG3209@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,26RI4@186822|Paenibacillaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
k59_184547_1	706587.Desti_2415	7.45e-62	202.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1MYKZ@1224|Proteobacteria,42SN9@68525|delta/epsilon subdivisions,2WP58@28221|Deltaproteobacteria,2MRMQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,SCP2
k59_6570_1	395493.BegalDRAFT_3111	2.23e-75	227.0	COG3829@1|root,COG3829@2|Bacteria,1QZHD@1224|Proteobacteria,1S631@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_137867_1	1123514.KB905899_gene985	5.52e-06	56.2	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,45ZPI@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_68456_2	1163407.UU7_02057	1.13e-10	63.5	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1X4J8@135614|Xanthomonadales	135614|Xanthomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_215305_3	1123237.Salmuc_04623	7.69e-22	100.0	COG1674@1|root,COG2319@1|root,COG1674@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2U3AU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_137869_1	1168034.FH5T_17450	4.53e-29	112.0	2C8RB@1|root,32RMP@2|Bacteria,4NTVV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_137869_2	376686.Fjoh_3148	5.55e-18	80.9	2C0BR@1|root,32RD6@2|Bacteria,4NQ5J@976|Bacteroidetes,1I397@117743|Flavobacteriia,2NVIA@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
k59_68459_1	1007103.AFHW01000030_gene2390	6.85e-20	96.3	COG1020@1|root,COG1020@2|Bacteria,1V047@1239|Firmicutes,4HF5K@91061|Bacilli,26VXE@186822|Paenibacillaceae	91061|Bacilli	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K15654	ko01054,ko02024,map01054,map02024	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_146269_1	1408473.JHXO01000008_gene2813	2.18e-19	94.4	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_137880_1	398720.MED217_14340	2.68e-62	205.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,2XI25@283735|Leeuwenhoekiella	976|Bacteroidetes	F	CTP synthase N-terminus	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_76267_1	338963.Pcar_0577	1.81e-123	367.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria,43W2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_29807_1	1056512.D515_00256	7.2e-100	302.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the RtcB family	rtcB	GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:0140098,GO:1901360	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_45116_1	1165841.SULAR_09389	2.28e-134	397.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2YRID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13,SPOR
k59_60589_1	2340.JV46_15750	9.23e-32	123.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1J5BU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_60589_2	1286106.MPL1_05664	1.95e-60	194.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,460HI@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_37672_1	1165841.SULAR_02698	7.95e-70	230.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2YRC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_6577_1	1192034.CAP_5226	4.63e-26	100.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,42TVD@68525|delta/epsilon subdivisions,2WQPX@28221|Deltaproteobacteria,2Z13W@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the bacterial histone-like protein family	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_45120_1	631362.Thi970DRAFT_02157	1.77e-51	176.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_37673_1	866536.Belba_3111	6.23e-59	201.0	COG4467@1|root,COG4467@2|Bacteria,4NV1D@976|Bacteroidetes,47VKZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_200125_1	1168034.FH5T_06100	2.98e-39	134.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	fkpA_1	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_200125_2	1168034.FH5T_06095	2.29e-36	135.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
k59_200127_2	190304.FN0366	2.38e-09	60.5	COG1109@1|root,COG1109@2|Bacteria,3788E@32066|Fusobacteria	32066|Fusobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_246260_1	1198232.CYCME_2188	2.86e-152	436.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,46037@72273|Thiotrichales	72273|Thiotrichales	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_223213_1	768671.ThimaDRAFT_4048	9.96e-39	141.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1WZGS@135613|Chromatiales	135613|Chromatiales	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_169366_1	87626.PTD2_03706	1.36e-35	142.0	COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,1RRJB@1236|Gammaproteobacteria,2Q1QT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	DZ	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,TIG
k59_94542_1	604331.AUHY01000035_gene2476	3.11e-36	136.0	COG3391@1|root,COG3391@2|Bacteria,1WICY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194969_1	1121937.AUHJ01000001_gene341	1.25e-52	167.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,1S4GD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k59_194969_2	1265313.HRUBRA_01876	7.94e-31	120.0	COG0439@1|root,COG0511@1|root,COG0439@2|Bacteria,COG0511@2|Bacteria,1N71M@1224|Proteobacteria,1RYJ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG0439 Biotin carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_63489_1	1049564.TevJSym_an00190	8.97e-45	153.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1J4NJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG2897 Rhodanese-related sulfurtransferase	rhdA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_63489_2	1035191.HMPREF0185_02514	8.68e-29	112.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,2KJSV@204458|Caulobacterales	204458|Caulobacterales	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_140931_1	1168034.FH5T_20510	5e-123	355.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_225975_1	1238450.VIBNISOn1_30267	2.59e-14	74.7	COG0318@1|root,COG0318@2|Bacteria,1R7EB@1224|Proteobacteria,1S123@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	ehpF	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_225975_2	9031.ENSGALP00000009534	0.000579	47.4	COG0591@1|root,KOG2349@2759|Eukaryota,38E3B@33154|Opisthokonta,3BA8Y@33208|Metazoa,3CRHR@33213|Bilateria,48BG0@7711|Chordata,496QT@7742|Vertebrata,4GUG9@8782|Aves	33208|Metazoa	P	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	SLC5A11	GO:0003674,GO:0005215,GO:0005355,GO:0005402,GO:0005412,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0008643,GO:0008645,GO:0015075,GO:0015077,GO:0015081,GO:0015144,GO:0015145,GO:0015149,GO:0015166,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015749,GO:0015791,GO:0015798,GO:0015850,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901618,GO:1904659	-	ko:K14158,ko:K14389,ko:K14391	ko04973,ko04976,ko04978,map04973,map04976,map04978	-	-	-	ko00000,ko00001,ko02000,ko04147	2.A.21.3,2.A.21.3.1,2.A.21.3.6	-	-	SSF
k59_140932_1	203122.Sde_0990	5.64e-113	336.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,46442@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_63504_1	32057.KB217478_gene397	9.61e-21	94.4	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,VPEP
k59_225979_1	161934.XP_010676254.1	2.6e-90	299.0	COG2801@1|root,KOG0017@2759|Eukaryota,3894V@33090|Viridiplantae,3GY0Z@35493|Streptophyta	35493|Streptophyta	T	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k59_140935_1	387093.SUN_1729	3.99e-74	224.0	COG1943@1|root,COG1943@2|Bacteria,1RF1K@1224|Proteobacteria,42VRT@68525|delta/epsilon subdivisions,2YQZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COGs COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_48103_1	498211.CJA_0059	4.21e-13	71.2	2BWJV@1|root,32U7J@2|Bacteria,1N47S@1224|Proteobacteria,1S8XJ@1236|Gammaproteobacteria,1FI8Q@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_24817_1	626887.J057_16960	4.55e-14	79.3	COG1879@1|root,COG1879@2|Bacteria,1MYP5@1224|Proteobacteria,1S84T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
k59_148505_1	1517416.IDAT_05135	1.44e-77	241.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,2QFBC@267893|Idiomarinaceae	1236|Gammaproteobacteria	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_0109	QRPTase_C,QRPTase_N
k59_140938_1	388413.ALPR1_11735	1.68e-31	120.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,47MTQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
k59_140938_2	1168034.FH5T_19565	4.75e-24	97.8	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,2G0DY@200643|Bacteroidia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_194994_1	1174528.JH992898_gene4034	1.25e-15	79.0	COG2831@1|root,COG2831@2|Bacteria,1GCGX@1117|Cyanobacteria,1JMVP@1189|Stigonemataceae	1117|Cyanobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
k59_63516_1	1168034.FH5T_15200	1.96e-57	192.0	2DM3I@1|root,31JQ3@2|Bacteria,4NRM4@976|Bacteroidetes,2FM1R@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63516_2	999419.HMPREF1077_03292	2.42e-21	92.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,2FMZT@200643|Bacteroidia,22X3K@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_148507_1	1168034.FH5T_03455	4.2e-21	90.9	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,2FNH7@200643|Bacteroidia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
k59_148507_2	1408473.JHXO01000006_gene1133	1.17e-32	124.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_202796_1	314230.DSM3645_26774	2.69e-22	99.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_202796_2	649747.HMPREF0083_06196	3.44e-09	60.5	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,26R1V@186822|Paenibacillaceae	91061|Bacilli	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_218325_1	1168034.FH5T_20555	4.38e-16	76.6	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia	976|Bacteroidetes	C	CoA binding domain protein	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_218325_2	1121451.DESAM_21610	1.24e-23	99.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_86735_2	930166.CD58_24885	8.23e-32	122.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1SZ0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k59_233865_1	416591.Tlet_0685	0.000804	44.7	COG2172@1|root,COG2172@2|Bacteria,2GDCV@200918|Thermotogae	200918|Thermotogae	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k59_94578_1	1165841.SULAR_02458	1.88e-157	457.0	COG2133@1|root,COG2133@2|Bacteria,1R0BJ@1224|Proteobacteria	1224|Proteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_94579_1	391619.PGA1_c01820	3.2e-12	68.2	COG0697@1|root,COG0697@2|Bacteria,1RAMR@1224|Proteobacteria,2UPH5@28211|Alphaproteobacteria,34G76@302485|Phaeobacter	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_94579_2	754477.Q7C_1497	4.95e-12	60.8	COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,1S8SP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	DnaK suppressor protein	ybiI	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
k59_140951_2	452637.Oter_0731	2.97e-18	85.5	COG1162@1|root,COG1162@2|Bacteria,46UNB@74201|Verrucomicrobia,3K75S@414999|Opitutae	414999|Opitutae	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_79099_1	314230.DSM3645_16145	1.13e-78	252.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_55804_1	292415.Tbd_2063	1.83e-101	312.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria,1KSQV@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoglucose isomerase	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_55804_2	1123393.KB891316_gene1367	3.78e-48	170.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,1KRR9@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glucokinase	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
k59_195010_1	1165841.SULAR_00290	9.65e-23	96.7	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_195010_2	1165841.SULAR_00285	1.63e-101	305.0	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,42VNT@68525|delta/epsilon subdivisions,2YRXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_32832_1	1163617.SCD_n00987	2.86e-52	169.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LemA Family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_32832_2	519989.ECTPHS_07576	1.95e-21	94.7	COG1704@1|root,COG1704@2|Bacteria,1RDUH@1224|Proteobacteria,1S2KR@1236|Gammaproteobacteria,1WY4K@135613|Chromatiales	135613|Chromatiales	S	E3 Ubiquitin ligase	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
k59_71163_1	713587.THITH_13535	1.18e-115	350.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1WXKA@135613|Chromatiales	135613|Chromatiales	G	PFAM Alpha amylase, catalytic	-	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_195013_1	1123405.AUMM01000027_gene2119	4.26e-26	111.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,26P81@186821|Sporolactobacillaceae	91061|Bacilli	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_133114_1	1122194.AUHU01000013_gene665	4.31e-35	131.0	COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Zonular occludens toxin (Zot)	-	-	-	-	-	-	-	-	-	-	-	-	Zot
k59_156312_1	485918.Cpin_0801	8.87e-44	147.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_63547_1	1185876.BN8_05143	8.15e-44	160.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,47K8Q@768503|Cytophagia	976|Bacteroidetes	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_125502_1	1144932.ATTF01000017_gene1171	8.7e-25	101.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
k59_71170_1	1202962.KB907162_gene4004	2.13e-27	111.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,1RMPP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_71170_2	398579.Spea_3886	4.24e-28	114.0	COG0304@1|root,COG0304@2|Bacteria,1P982@1224|Proteobacteria,1S9YX@1236|Gammaproteobacteria,2Q9YK@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
k59_71170_3	1219031.BBJR01000071_gene1116	4.21e-15	72.4	COG4706@1|root,COG4706@2|Bacteria,1N00A@1224|Proteobacteria,2VW4W@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Dehydratase	fabZ2	-	-	-	-	-	-	-	-	-	-	-	FabA
k59_226000_1	1168067.JAGP01000001_gene381	1.81e-33	120.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,46109@72273|Thiotrichales	72273|Thiotrichales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_226000_2	1049564.TevJSym_ac02050	4.51e-61	204.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1J4QZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_48454_1	215803.DB30_4501	1.68e-79	259.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_25225_1	575540.Isop_1362	3.42e-07	57.4	COG4145@1|root,COG4145@2|Bacteria,2IYD0@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.1	-	-	SSF
k59_56091_1	371731.Rsw2DRAFT_2137	4.76e-15	75.9	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2TR2N@28211|Alphaproteobacteria,1FB6T@1060|Rhodobacter	28211|Alphaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_56091_2	550540.Fbal_3152	1.64e-42	149.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KO	Hydrogenase accessory protein HypB	hypB	GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010467,GO:0016151,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:1901564	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_40774_1	1165841.SULAR_00480	1.45e-84	258.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2YMYR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_40774_2	1565314.OA34_03615	2.95e-13	69.7	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2YMMP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_79439_1	290512.Paes_1843	3.59e-18	90.1	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_195472_1	266265.Bxe_A4054	1.02e-10	62.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,1JZWP@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_195472_2	765911.Thivi_4240	1.7e-32	119.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1WVVE@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_87064_1	1121405.dsmv_3780	3.4e-89	273.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_118151_1	1304284.L21TH_1239	9.81e-112	330.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,36DQ3@31979|Clostridiaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
k59_56103_1	870187.Thini_2729	3.6e-81	247.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,460KA@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_56103_2	631362.Thi970DRAFT_00794	4.89e-07	51.6	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1WY2Z@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_48469_1	1163617.SCD_n01213	2.15e-60	196.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria	28216|Betaproteobacteria	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_87068_2	7668.SPU_019939-tr	2.94e-35	124.0	COG0537@1|root,KOG3275@2759|Eukaryota,3A3J2@33154|Opisthokonta,3BRD5@33208|Metazoa,3D8AA@33213|Bilateria	33208|Metazoa	T	purine ribonucleotide catabolic process	HINT2	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009892,GO:0010605,GO:0016042,GO:0019222,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0080090,GO:1901575,GO:1901983,GO:1901984,GO:2000756,GO:2000757	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_148891_1	472759.Nhal_2111	1.73e-40	149.0	29DE2@1|root,300BX@2|Bacteria,1NC7M@1224|Proteobacteria,1SFWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128731_1	349521.HCH_02749	1.94e-16	79.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1XIV3@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_128731_2	765911.Thivi_4259	5.76e-40	145.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WXWZ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_151653_1	574376.BAMA_17490	2.87e-104	310.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus	91061|Bacilli	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_113102_1	1168034.FH5T_04395	4.83e-58	192.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes	976|Bacteroidetes	E	Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_113102_2	445970.ALIPUT_01971	3.62e-11	62.4	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,22U5J@171550|Rikenellaceae	976|Bacteroidetes	T	histidine kinase DNA gyrase B	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_144308_1	1168034.FH5T_06980	3.3e-97	292.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,2FQ9F@200643|Bacteroidia	976|Bacteroidetes	S	Ser Thr phosphatase family protein	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_121039_1	3649.evm.model.supercontig_23.86	4.49e-15	69.7	2EP17@1|root,2SSB9@2759|Eukaryota,380HF@33090|Viridiplantae,3GQ31@35493|Streptophyta,3I1B7@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_121039_3	218851.Aquca_064_00050.1	1.4e-19	81.3	2D6E7@1|root,2T1Q5@2759|Eukaryota,382XC@33090|Viridiplantae,3GRGP@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_121039_4	981085.XP_010109403.1	3.21e-36	122.0	2D40V@1|root,2STG3@2759|Eukaryota,381GS@33090|Viridiplantae,3GMA3@35493|Streptophyta,4JUQW@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159475_1	1168034.FH5T_04425	9.1e-40	137.0	COG3884@1|root,COG3884@2|Bacteria,4NMMY@976|Bacteroidetes,2FQ43@200643|Bacteroidia	976|Bacteroidetes	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
k59_159475_2	1168034.FH5T_04420	5.31e-16	75.5	COG0024@1|root,COG0024@2|Bacteria,4NIMB@976|Bacteroidetes,2FM2H@200643|Bacteroidia	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_190558_1	251229.Chro_2394	1.52e-13	73.2	COG0737@1|root,COG0737@2|Bacteria,1G262@1117|Cyanobacteria,3VKV4@52604|Pleurocapsales	1117|Cyanobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,EF-hand_5,Metallophos
k59_151673_1	1118153.MOY_16502	7.48e-38	135.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RSHU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	tnpB	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_151673_2	1121106.JQKB01000042_gene2461	6.87e-41	137.0	COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2UC5K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_66757_1	247634.GPB2148_3206	4.02e-79	241.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1SABB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_244630_1	565045.NOR51B_1552	3.83e-30	122.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1J4WW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590	CN_hydrolase
k59_121052_1	765914.ThisiDRAFT_0220	1.43e-70	224.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1WX9E@135613|Chromatiales	135613|Chromatiales	E	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_89772_1	2340.JV46_20760	1.11e-88	271.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1J4UM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_144327_1	1283300.ATXB01000001_gene1696	2.59e-67	223.0	COG0475@1|root,COG0475@2|Bacteria,1R5QJ@1224|Proteobacteria,1RSM6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_144327_2	1288826.MSNKSG1_00516	1.06e-12	68.2	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,469CA@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_151684_1	1165841.SULAR_06158	1.83e-39	142.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_151684_2	1165841.SULAR_06153	5.6e-58	180.0	COG4627@1|root,COG4627@2|Bacteria,1NHR6@1224|Proteobacteria,42VA4@68525|delta/epsilon subdivisions,2YQEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Stress responsive A B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
k59_151684_3	1165841.SULAR_06148	6.61e-09	55.5	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2YNXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_205944_1	1009370.ALO_14397	1.63e-51	184.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H2S2@909932|Negativicutes	909932|Negativicutes	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_12447_1	1004785.AMBLS11_10530	6.92e-43	159.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_28022_1	214092.YPO2352	1.68e-41	147.0	COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,1RND4@1236|Gammaproteobacteria,41EDJ@629|Yersinia	1236|Gammaproteobacteria	T	psp operon transcriptional activator	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_28022_2	13349.G1X445	1.12e-11	64.7	COG0345@1|root,KOG3124@2759|Eukaryota,39QSG@33154|Opisthokonta,3NVU1@4751|Fungi,3QP95@4890|Ascomycota	4751|Fungi	E	Belongs to the pyrroline-5-carboxylate reductase family	PRO3	GO:0003674,GO:0003824,GO:0004735,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_105187_1	640081.Dsui_2185	6.71e-12	62.8	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,2KWA8@206389|Rhodocyclales	206389|Rhodocyclales	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_105187_2	523791.Kkor_0854	1.26e-22	94.7	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1XIPY@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
k59_121066_1	519989.ECTPHS_13218	1e-109	349.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_144341_1	595460.RRSWK_03621	3.69e-57	192.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,Laminin_G_3
k59_89777_1	1165841.SULAR_05503	6.79e-152	434.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_89777_2	1165841.SULAR_05508	1.15e-38	142.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_159497_1	1121405.dsmv_0881	2.58e-08	53.9	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria,2MMAB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159497_2	555779.Dthio_PD0052	2.42e-38	141.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MGHZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_221482_1	329726.AM1_1186	6.01e-28	118.0	COG0515@1|root,COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Pkinase,Response_reg
k59_74508_1	1165841.SULAR_02253	1.34e-44	153.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,431SV@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_74508_2	1165841.SULAR_02258	1.1e-32	125.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria	1224|Proteobacteria	S	glutamate--cysteine ligase	ybdK_1	-	-	-	-	-	-	-	-	-	-	-	GCS2
k59_136282_1	4641.GSMUA_Achr3P22530_001	2.36e-05	50.1	COG3424@1|root,2QRSY@2759|Eukaryota,37MT6@33090|Viridiplantae,3G7AK@35493|Streptophyta,3KWTV@4447|Liliopsida	35493|Streptophyta	H	Belongs to the chalcone stilbene synthases family	-	-	2.3.1.74	ko:K00660	ko00941,ko01100,ko01110,ko04712,map00941,map01100,map01110,map04712	M00137	R01613,R06568,R07987,R07988,R07989	RC00004,RC02726	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
k59_36004_1	1168034.FH5T_05115	1.3e-38	143.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,2FNKR@200643|Bacteroidia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_36004_2	626522.GCWU000325_01992	1.56e-10	57.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,2FTUG@200643|Bacteroidia,1WDGU@1283313|Alloprevotella	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_198429_1	2340.JV46_28300	6.17e-88	262.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1J5Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_36005_1	1168034.FH5T_19710	1.07e-63	203.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_74509_1	1295642.H839_04799	8.57e-94	289.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,1WEQK@129337|Geobacillus	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
k59_74510_1	1123277.KB893190_gene4913	2.89e-05	52.4	COG2885@1|root,COG2885@2|Bacteria,4NGCV@976|Bacteroidetes,47K14@768503|Cytophagia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_214110_1	1159870.KB907784_gene2192	4.47e-30	122.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2VKSJ@28216|Betaproteobacteria,3T9IC@506|Alcaligenaceae	28216|Betaproteobacteria	S	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_198908_1	1165841.SULAR_05233	9.38e-138	393.0	COG2204@1|root,COG2204@2|Bacteria,1QASN@1224|Proteobacteria,42RV2@68525|delta/epsilon subdivisions,2YP76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activ_2,Sigma54_activat
k59_237376_2	313596.RB2501_00351	6.61e-70	227.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1HXUQ@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_90138_1	1168034.FH5T_07055	4e-36	125.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,2FS1V@200643|Bacteroidia	976|Bacteroidetes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_90138_2	1168034.FH5T_07060	3.1e-22	94.4	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,2FP71@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_191008_1	1165841.SULAR_01110	2.6e-31	115.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_191008_2	1165841.SULAR_01115	1.11e-72	226.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,42Q6E@68525|delta/epsilon subdivisions,2YQCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
k59_20395_1	1168034.FH5T_15315	1.33e-54	190.0	COG2866@1|root,COG2866@2|Bacteria,4NHBS@976|Bacteroidetes	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_136649_1	1168034.FH5T_03150	2.67e-40	144.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,2FNFB@200643|Bacteroidia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_198912_1	4081.Solyc01g007640.2.1	1.6e-92	301.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_206270_1	1165841.SULAR_08070	6.04e-61	189.0	COG2346@1|root,COG2346@2|Bacteria,1Q5UZ@1224|Proteobacteria,42U39@68525|delta/epsilon subdivisions,2YPTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_175238_1	1168034.FH5T_17590	2.76e-38	142.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,2G2QE@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
k59_175238_2	1168034.FH5T_17585	1.65e-32	127.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,2FW70@200643|Bacteroidia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98095_1	1004149.AFOE01000031_gene478	3.63e-13	69.7	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
k59_221881_1	1343158.SACS_0167	9.13e-08	58.2	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2JPMS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_121569_2	1165841.SULAR_06618	6.8e-41	140.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2YP2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	nssR	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_74908_1	396595.TK90_2291	2.5e-52	172.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1WXFP@135613|Chromatiales	135613|Chromatiales	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_74908_2	132113.XP_003493810.1	2.95e-13	69.3	COG0452@1|root,COG0756@1|root,KOG0672@2759|Eukaryota,KOG3370@2759|Eukaryota,3A3J6@33154|Opisthokonta,3BRMT@33208|Metazoa,3D85X@33213|Bilateria,427HS@6656|Arthropoda,3SQD6@50557|Insecta	33208|Metazoa	DP	Coenzyme A biosynthesis bifunctional protein CoaBC-like	-	-	-	-	-	-	-	-	-	-	-	-	DFP,Flavoprotein
k59_221883_1	1165841.SULAR_02928	8.85e-83	247.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2YP5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase maturation protease	hydD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_221883_2	1165841.SULAR_02933	6.12e-76	233.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	hydC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_191015_1	1165841.SULAR_00160	4.33e-107	318.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_136657_2	292414.TM1040_1650	5.47e-08	55.8	COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,4NDDG@97050|Ruegeria	28211|Alphaproteobacteria	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_1,PG_binding_3
k59_198917_1	1267535.KB906767_gene3318	1.29e-19	89.0	COG0665@1|root,COG0665@2|Bacteria,3Y6FK@57723|Acidobacteria,2JKN4@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_90149_1	857087.Metme_4580	1.48e-25	101.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,1S6PD@1236|Gammaproteobacteria,1XFCI@135618|Methylococcales	135618|Methylococcales	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
k59_90149_2	1249627.D779_1330	2.32e-54	177.0	COG4636@1|root,COG4636@2|Bacteria,1RH5Y@1224|Proteobacteria,1S823@1236|Gammaproteobacteria,1WYPU@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_221890_2	1442598.JABW01000017_gene1945	7.27e-207	586.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2YRPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_136664_1	998674.ATTE01000001_gene2474	1.14e-81	247.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_71213_2	1122599.AUGR01000001_gene205	7.91e-17	77.4	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1XJIB@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_63587_1	1469245.JFBG01000010_gene616	5.14e-12	65.5	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,1RQPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC-Type Dipeptide Transport System Periplasmic Component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5,TAT_signal
k59_63587_2	998674.ATTE01000001_gene265	1.53e-61	202.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RMJ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	choline-sulfatase	betC	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,DUF4976,Sulfatase
k59_164131_1	1168065.DOK_02406	1.3e-24	99.8	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1J6FU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k59_241484_1	94122.Shewana3_3543	9e-21	96.3	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9
k59_1812_1	1122939.ATUD01000003_gene3537	0.000844	48.5	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4CQ6W@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_48198_1	1246484.D479_12398	1.34e-15	81.6	COG2027@1|root,COG2027@2|Bacteria,1TQFQ@1239|Firmicutes,4HA3X@91061|Bacilli,3NE4H@45667|Halobacillus	91061|Bacilli	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacC	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k59_48199_1	313596.RB2501_09505	3.61e-86	274.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1HWMX@117743|Flavobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_195111_1	591167.Sfla_5823	3.95e-16	80.1	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
k59_226057_1	1125863.JAFN01000001_gene2568	2.22e-23	108.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_125568_1	882378.RBRH_01359	1.21e-35	124.0	2D16E@1|root,32TA0@2|Bacteria,1MZ7W@1224|Proteobacteria,2VU9S@28216|Betaproteobacteria,1K9M8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Motility quorum-sensing regulator, toxin of MqsA	-	-	-	ko:K13651	-	-	-	-	ko00000,ko02048	-	-	-	MqsR_toxin
k59_125568_2	637390.AFOH01000056_gene1573	1.19e-74	225.0	COG1396@1|root,COG1396@2|Bacteria,1QVJF@1224|Proteobacteria,1T2EB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K13655	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	MqsA_antitoxin
k59_1816_1	1227457.C451_00890	2.58e-44	158.0	COG4279@1|root,arCOG03431@2157|Archaea,2Y44T@28890|Euryarchaeota	28890|Euryarchaeota	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
k59_40501_1	765913.ThidrDRAFT_2017	7.08e-12	62.8	2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,1S614@1236|Gammaproteobacteria,1WYK8@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40501_2	1158762.KB898047_gene580	1.98e-38	134.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the HSP15 family	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
k59_40501_3	2340.JV46_10140	5.85e-38	129.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1J6Z4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k59_141046_1	349521.HCH_02430	1.43e-76	239.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XH6T@135619|Oceanospirillales	135619|Oceanospirillales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_218408_1	196490.AUEZ01000043_gene6934	1.26e-50	183.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2TUI1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_71228_1	1249480.B649_03600	5.51e-21	97.8	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,42NZJ@68525|delta/epsilon subdivisions,2YT09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	Glug,Haemagg_act
k59_48204_1	945550.VISI1226_04582	1.55e-146	427.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XU3K@135623|Vibrionales	135623|Vibrionales	U	Belongs to the BCCT transporter (TC 2.A.15) family	butA	-	-	ko:K03451	-	-	-	-	ko00000	2.A.15	-	-	BCCT
k59_125576_1	998088.B565_0243	2.76e-110	336.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1Y50P@135624|Aeromonadales	135624|Aeromonadales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_71237_2	1049564.TevJSym_am00320	3.66e-33	124.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1J9H8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_171953_1	313596.RB2501_07760	1.39e-82	253.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_71239_1	1232447.BAHW02000023_gene1589	1.34e-23	102.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,267M7@186813|unclassified Clostridiales	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_40516_1	1165841.SULAR_07635	3.05e-46	162.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_32948_1	984892.SPSE_1990	2.92e-46	162.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,4GX4X@90964|Staphylococcaceae	91061|Bacilli	M	transferase	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_48218_1	2340.JV46_07910	2.83e-63	207.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,1J816@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
k59_24939_1	634499.EpC_31610	1.12e-59	207.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
k59_102238_1	656024.FsymDg_4189	5.09e-26	105.0	COG2267@1|root,COG2267@2|Bacteria,2I94I@201174|Actinobacteria,4EU87@85013|Frankiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_71251_1	1123518.ARWI01000001_gene2323	8.19e-06	50.8	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,4611P@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
k59_71251_2	367737.Abu_2318	5.8e-57	193.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1831_1	344747.PM8797T_32295	1.61e-50	181.0	COG0539@1|root,COG0539@2|Bacteria,2IXPK@203682|Planctomycetes	203682|Planctomycetes	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_218421_1	1408473.JHXO01000011_gene3144	3.18e-91	288.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,2FNBD@200643|Bacteroidia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_218421_2	1168034.FH5T_14120	3.13e-25	99.4	28H8Z@1|root,30SVU@2|Bacteria,4NY56@976|Bacteroidetes	976|Bacteroidetes	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
k59_102240_1	747.DR93_1086	5.26e-48	174.0	COG1203@1|root,COG1203@2|Bacteria,1MVZF@1224|Proteobacteria,1RQH5@1236|Gammaproteobacteria,1Y76R@135625|Pasteurellales	135625|Pasteurellales	L	CRISPR-associated helicase, Cas3	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
k59_17143_1	1265503.KB905160_gene2838	7.79e-41	151.0	COG3119@1|root,COG3119@2|Bacteria,1R9FP@1224|Proteobacteria,1RNDW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_86832_1	1165841.SULAR_07815	2.93e-58	184.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_86832_2	1165841.SULAR_07810	4.07e-52	176.0	COG0457@1|root,COG0457@2|Bacteria,1NR72@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79206_1	234267.Acid_1208	7.75e-24	105.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
k59_40534_1	1165841.SULAR_06318	2.1e-25	105.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_40534_2	1165841.SULAR_06323	2.61e-50	161.0	COG0745@1|root,COG0745@2|Bacteria,1NEVF@1224|Proteobacteria,43C0G@68525|delta/epsilon subdivisions,2YTED@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413,ko:K07814	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_17150_1	1117319.PSPO_20361	1.62e-37	145.0	COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,1RRJB@1236|Gammaproteobacteria,2Q1QT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	DZ	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,TIG
k59_226081_1	519989.ECTPHS_01544	2.82e-24	95.1	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1WZ88@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_226081_2	187272.Mlg_2612	3.95e-15	70.9	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_202908_1	1304883.KI912532_gene796	4.27e-22	97.4	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,2KU7G@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_9634_1	3880.AES87815	0.00035	42.4	2D08W@1|root,2SD7U@2759|Eukaryota,37XFR@33090|Viridiplantae,3GMII@35493|Streptophyta	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface	psbM	-	-	ko:K02714	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbM
k59_48234_1	1116375.VEJY3_06860	3.62e-71	219.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1XUS7@135623|Vibrionales	135623|Vibrionales	E	Urea ABC transporter ATP-binding protein	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
k59_48234_2	1144342.PMI40_04847	5.4e-07	50.8	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2VIX4@28216|Betaproteobacteria,473R9@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	urtD	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
k59_55905_1	399742.Ent638_2010	3.98e-13	72.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,3X0KK@547|Enterobacter	1236|Gammaproteobacteria	T	Diguanylate cyclase	adrA	-	2.7.7.65	ko:K18968	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko02000	9.B.34.1.2	-	-	GGDEF,MASE2
k59_63634_1	472759.Nhal_2774	9.7e-08	49.7	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1WYZR@135613|Chromatiales	135613|Chromatiales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_63634_2	2340.JV46_20660	1.93e-155	458.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1J4NM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_133203_1	240016.ABIZ01000001_gene4912	2.72e-18	90.5	COG2010@1|root,COG2010@2|Bacteria,46URX@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
k59_79219_1	1267535.KB906767_gene2339	7.17e-29	108.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria,2JNEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
k59_179723_1	1165841.SULAR_00425	5.01e-141	414.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_202920_1	118168.MC7420_3767	1.51e-30	111.0	COG4374@1|root,COG4374@2|Bacteria,1G9CN@1117|Cyanobacteria,1HG68@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_202920_2	163908.KB235896_gene2034	1.05e-18	80.1	COG2002@1|root,COG2002@2|Bacteria,1GARU@1117|Cyanobacteria,1HQ13@1161|Nostocales	1117|Cyanobacteria	K	TIGRFAM looped-hinge helix DNA binding domain, AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
k59_226091_1	1168034.FH5T_11965	2.14e-114	340.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,2FS28@200643|Bacteroidia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_24967_1	985665.HPL003_07770	2.09e-60	192.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,26SCN@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
k59_148624_1	1157490.EL26_10200	6.12e-12	65.1	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,2783B@186823|Alicyclobacillaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSB619.SA_RS10970,iYO844.BSU36820	ATP-synt
k59_148624_2	1192034.CAP_3138	1.75e-73	240.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2YUF7@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_79228_1	1337936.IJ00_06645	3.58e-53	181.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1HQWN@1161|Nostocales	1117|Cyanobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_234039_1	1121344.JHZO01000005_gene9	1.44e-05	45.8	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3WGQM@541000|Ruminococcaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_10311_1	1220589.CD32_08585	1.49e-07	57.8	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4HCGU@91061|Bacilli,3IWAI@400634|Lysinibacillus	91061|Bacilli	M	3D domain	yocH	-	-	-	-	-	-	-	-	-	-	-	3D,LysM
k59_87459_1	765913.ThidrDRAFT_2740	1.07e-66	231.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WXP6@135613|Chromatiales	135613|Chromatiales	O	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_17694_1	395493.BegalDRAFT_2200	1.66e-140	416.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,45ZWJ@72273|Thiotrichales	72273|Thiotrichales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_17694_2	911045.PSE_4328	1.57e-55	181.0	COG0310@1|root,COG0310@2|Bacteria,1MXW7@1224|Proteobacteria,2U9W2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
k59_135945_1	72658.Bostr.12474s0002.1.p	2.5e-52	167.0	COG1005@1|root,KOG4770@2759|Eukaryota,37XCB@33090|Viridiplantae,3GWP4@35493|Streptophyta,3I0BQ@3699|Brassicales	35493|Streptophyta	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K03878	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_221176_1	1121440.AUMA01000009_gene695	1.46e-63	206.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria,2M8UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_19689_2	203122.Sde_3027	1.49e-07	55.5	COG5266@1|root,COG5266@2|Bacteria,1MXQS@1224|Proteobacteria,1RREM@1236|Gammaproteobacteria,465TT@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Domain of unknown function (DUF4198)	VPA0159	-	-	-	-	-	-	-	-	-	-	-	DUF4198
k59_143875_1	1178482.BJB45_10100	3.23e-57	201.0	COG5290@1|root,COG5290@2|Bacteria,1N3KW@1224|Proteobacteria,1S12W@1236|Gammaproteobacteria,1XP8P@135619|Oceanospirillales	135619|Oceanospirillales	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213351_3	1267534.KB906757_gene1063	2.84e-11	64.7	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_128415_1	1123368.AUIS01000004_gene134	4.49e-40	146.0	COG1563@1|root,COG1563@2|Bacteria,1RB3N@1224|Proteobacteria,1S74H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040,MnhB
k59_4712_1	2074.JNYD01000052_gene1551	2.31e-56	194.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4EAD5@85010|Pseudonocardiales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_167158_1	1165841.SULAR_00710	1.3e-172	522.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_120658_1	313596.RB2501_06640	3.19e-64	209.0	28JCX@1|root,2Z97G@2|Bacteria,4NII8@976|Bacteroidetes,1I0YE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43180_1	1564096.A0A0A0YRA9_9CAUD	2.61e-29	133.0	4QEE7@10239|Viruses,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_58534_1	398767.Glov_3652	5.04e-05	44.3	COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,42YTR@68525|delta/epsilon subdivisions,2WUKA@28221|Deltaproteobacteria,43T4W@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k59_35586_1	1123400.KB904769_gene2778	9.29e-89	270.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the citrate synthase family	prpC	GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	iECED1_1282.ECED1_0365,iECIAI1_1343.ECIAI1_0334,iECIAI39_1322.ECIAI39_0347,iECP_1309.ECP_0408,iECSF_1327.ECSF_0308,iEcE24377_1341.EcE24377A_0357,iJN746.PP_2335,iLF82_1304.LF82_1740,iNRG857_1313.NRG857_01630	Citrate_synt
k59_35586_2	349106.PsycPRwf_1197	8.78e-20	86.3	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,3NJAS@468|Moraxellaceae	1236|Gammaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407	PEP_mutase
k59_143889_1	1342299.Z947_1704	9.73e-74	228.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TTSX@28211|Alphaproteobacteria,3ZX4H@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
k59_213368_1	2340.JV46_24660	3.99e-76	233.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,1S42J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_228716_1	1121334.KB911072_gene2638	4.04e-62	219.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WGTE@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	EAL,GAF,GGDEF,HisKA_7TM,PAS_3,PAS_9,SBP_bac_3
k59_81850_1	756272.Plabr_3397	8.24e-81	255.0	COG3119@1|root,COG3119@2|Bacteria,2IX2H@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
k59_236710_2	323261.Noc_1622	6.53e-33	124.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,1S11K@1236|Gammaproteobacteria,1X0A6@135613|Chromatiales	135613|Chromatiales	H	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_89494_1	63737.Npun_F1213	2.29e-88	293.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HK2M@1161|Nostocales	1117|Cyanobacteria	S	C-terminal of Roc, COR, domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_1,LRR_4,LRR_8,LRR_9,Roc
k59_43194_1	688245.CtCNB1_3147	1.29e-88	269.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,2VIXZ@28216|Betaproteobacteria,4AB73@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	-	-	4.1.3.39,4.1.3.43	ko:K01666,ko:K18365	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750,R05298	RC00307,RC00371,RC00572	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
k59_120669_1	1232437.KL662006_gene4382	1.09e-24	100.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2MHV3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_58546_1	1123393.KB891328_gene533	2.12e-56	190.0	COG0475@1|root,COG0475@2|Bacteria,1PK6S@1224|Proteobacteria,2VZ60@28216|Betaproteobacteria,1KTFQ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_143896_1	2340.JV46_04130	1.28e-57	189.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1J4KY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	iPC815.YPO2896,iYL1228.KPN_02862	Aminotran_5
k59_143896_2	1453501.JELR01000001_gene3025	1.22e-50	162.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,466TH@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055	NifU_N
k59_190191_1	387093.SUN_0532	1.06e-83	267.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,43CM6@68525|delta/epsilon subdivisions,2YTE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_66362_1	555779.Dthio_PD0367	1.18e-35	134.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,42T2F@68525|delta/epsilon subdivisions,2WPGM@28221|Deltaproteobacteria,2MGHA@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
k59_213374_3	298386.PBPRB0091	2.7e-32	116.0	2C1A0@1|root,3329F@2|Bacteria,1N99D@1224|Proteobacteria,1SD1S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Type VI secretion system (T6SS), amidase effector protein 4	-	-	-	-	-	-	-	-	-	-	-	-	Tae4
k59_143898_1	1250005.PHEL85_0893	8.43e-37	137.0	COG1472@1|root,COG1472@2|Bacteria,4NJGK@976|Bacteroidetes,1HZ5M@117743|Flavobacteriia,3VVTB@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
k59_27677_1	399739.Pmen_0298	4.06e-23	94.4	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1SDU8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_143900_1	1165841.SULAR_01200	4.32e-72	220.0	COG1917@1|root,COG1917@2|Bacteria,1MZFB@1224|Proteobacteria	1224|Proteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_67109_1	1095769.CAHF01000022_gene432	2.01e-68	234.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_128937_1	313612.L8106_01902	8.33e-26	108.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_128937_2	870187.Thini_0240	3.54e-43	142.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,1T0H0@1236|Gammaproteobacteria,461BU@72273|Thiotrichales	72273|Thiotrichales	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_20229_1	768710.DesyoDRAFT_2480	8.09e-06	47.8	COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,24BK2@186801|Clostridia,262Y3@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_97925_1	387093.SUN_2338	1.14e-45	150.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2YNWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_97925_2	1165841.SULAR_07950	1.19e-71	216.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2YPXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_105462_1	1165841.SULAR_06318	2.05e-78	261.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_43742_1	313596.RB2501_02985	1.07e-100	299.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1HWY7@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_97927_1	767817.Desgi_3751	1.24e-41	155.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,260IQ@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM potassium uptake protein, TrkH family	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_175067_1	388413.ALPR1_11965	2.31e-56	194.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47TP1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_36221_1	765911.Thivi_0477	2.81e-41	151.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria,1WX4F@135613|Chromatiales	135613|Chromatiales	P	ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
k59_28229_1	1454004.AW11_02485	1.03e-136	392.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_5198_1	1002340.AFCF01000007_gene2927	5.57e-58	197.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,34F4N@302485|Phaeobacter	28211|Alphaproteobacteria	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
k59_113353_1	748280.NH8B_2354	3.8e-32	122.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria,2KR7R@206351|Neisseriales	206351|Neisseriales	K	MAATS-type transcriptional repressor, C-terminal region	mtrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
k59_121431_1	387093.SUN_1882	1.27e-49	159.0	COG0776@1|root,COG0776@2|Bacteria,1QQYR@1224|Proteobacteria,42V36@68525|delta/epsilon subdivisions,2YQA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the bacterial histone-like protein family	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_221647_1	59689.scaffold_201045.1	0.0	976.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,3I0YM@3699|Brassicales	35493|Streptophyta	K	rna polymerase	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_221647_2	13333.ERN02618	1.19e-246	726.0	COG0052@1|root,COG0356@1|root,KOG0832@2759|Eukaryota,KOG4665@2759|Eukaryota,38964@33090|Viridiplantae,3GY32@35493|Streptophyta	35493|Streptophyta	J	RNA polymerase Rpb1, domain 5	rpoC2	-	2.7.7.6	ko:K02108,ko:K03046	ko00190,ko00195,ko00230,ko00240,ko01100,ko03020,map00190,map00195,map00230,map00240,map01100,map03020	M00157,M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko00194,ko01000,ko03021,ko03110,ko03400	3.A.2.1	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,Ribosomal_S2
k59_175070_1	330084.JNYZ01000006_gene1219	1.93e-10	65.9	COG1309@1|root,COG1309@2|Bacteria,2HK4X@201174|Actinobacteria,4E2PT@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	kstR2	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22108	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
k59_74705_1	411468.CLOSCI_01376	1.14e-06	58.2	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,21XNZ@1506553|Lachnoclostridium	186801|Clostridia	M	Penicillin binding protein transpeptidase domain	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
k59_136462_3	1137281.D778_02686	5.76e-23	95.9	COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,1I0U6@117743|Flavobacteriia	976|Bacteroidetes	H	Acetyltransferase (Isoleucine patch superfamily)	vat_2	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k59_183053_1	1415778.JQMM01000001_gene2182	1.31e-23	97.1	COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP synthase gamma subunit	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_183053_2	1415778.JQMM01000001_gene2181	7.27e-53	181.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_206133_1	1168034.FH5T_12140	4.52e-174	497.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,2FNQZ@200643|Bacteroidia	976|Bacteroidetes	P	potassium uptake protein, TrkH family	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_213956_2	1122185.N792_10940	9.99e-16	72.8	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1X7UU@135614|Xanthomonadales	135614|Xanthomonadales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
k59_151991_1	1191523.MROS_0163	1.52e-67	213.0	COG0121@1|root,COG0121@2|Bacteria	2|Bacteria	S	cellular modified histidine biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k59_186983_2	929558.SMGD1_0192	1.08e-09	59.7	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42NJQ@68525|delta/epsilon subdivisions,2YMZP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	hmm pf00563	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_148268_2	331678.Cphamn1_1572	5.74e-08	52.0	2EGU9@1|root,33AKF@2|Bacteria	2|Bacteria	S	Addiction module component, TIGR02574 family	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
k59_70898_1	1033736.CAHK01000037_gene2524	3.5e-15	78.6	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4F9J8@85019|Brevibacteriaceae	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_117420_1	349521.HCH_04426	1.21e-27	103.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,1S5VV@1236|Gammaproteobacteria,1XPKY@135619|Oceanospirillales	135619|Oceanospirillales	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_125148_1	395493.BegalDRAFT_2231	1.34e-69	221.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,461RD@72273|Thiotrichales	72273|Thiotrichales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_125148_2	1042375.AFPL01000035_gene2825	0.00014	43.9	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,4664T@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	ygaD	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_163814_1	1279017.AQYJ01000029_gene3960	7.63e-102	318.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
k59_241063_1	880070.Cycma_2756	1.26e-06	55.5	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
k59_117425_2	443906.CMM_0424	7.5e-19	93.6	COG1129@1|root,COG1129@2|Bacteria,2IAXH@201174|Actinobacteria,4FRB8@85023|Microbacteriaceae	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k59_218049_1	1168034.FH5T_19665	3.19e-89	286.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_117427_1	1206725.BAFU01000044_gene2072	3.49e-08	55.1	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4G32Q@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_117427_2	1163617.SCD_n00527	3.56e-17	75.5	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,2W5RM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_125155_1	1183438.GKIL_1366	1.67e-28	120.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	ASH,Cadherin-like,DUF1573,TIG,VWA
k59_194737_1	396588.Tgr7_0009	1.7e-50	167.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S27K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,MipZ
k59_163820_2	697282.Mettu_2681	3.78e-57	199.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1XDR7@135618|Methylococcales	135618|Methylococcales	KL	DNA RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
k59_179354_1	452662.SJA_C1-30320	1.39e-61	213.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TTHU@28211|Alphaproteobacteria,2K9A6@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_156005_2	487316.BBNM01000001_gene1615	4.28e-19	87.8	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,3NIXE@468|Moraxellaceae	1236|Gammaproteobacteria	J	Methylates ribosomal protein L11	prmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_9218_1	1347393.HG726020_gene1096	1.33e-21	97.4	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,2FNBU@200643|Bacteroidia,4AMWR@815|Bacteroidaceae	976|Bacteroidetes	HQ	Isochorismate synthase	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
k59_117435_1	439235.Dalk_4847	7.19e-47	164.0	COG3385@1|root,COG3385@2|Bacteria,1RCTP@1224|Proteobacteria,431NI@68525|delta/epsilon subdivisions,2WWWQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_24512_1	927677.ALVU02000001_gene1682	2.49e-13	74.3	COG2201@1|root,COG2201@2|Bacteria,1G1EA@1117|Cyanobacteria	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1386_1	742727.HMPREF9447_03644	1.98e-12	72.8	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FRNU@200643|Bacteroidia,4ANQV@815|Bacteroidaceae	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_63201_1	1165841.SULAR_03767	1.92e-167	473.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_78732_1	1244856.K4PWR5_9CAUD	7.91e-19	86.3	4QEDJ@10239|Viruses,4QZ5Q@35237|dsDNA viruses  no RNA stage,4QPM4@28883|Caudovirales,4QP27@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210632_2	395493.BegalDRAFT_0153	1.16e-60	194.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,461IU@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_55977_1	1165841.SULAR_07460	1.88e-157	450.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2YMPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_55977_2	1165841.SULAR_07465	2.2e-13	63.9	29H9G@1|root,30470@2|Bacteria,1QR1D@1224|Proteobacteria,42TWI@68525|delta/epsilon subdivisions,2YPSP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9700_1	511145.b4475	3.95e-67	218.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria,3XMP7@561|Escherichia	1236|Gammaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
k59_25048_1	1382359.JIAL01000001_gene901	5.22e-64	219.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_117944_1	382464.ABSI01000021_gene439	1.03e-37	142.0	COG3829@1|root,COG3829@2|Bacteria,46Z7D@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
k59_63719_1	525898.Sdel_1999	5.15e-142	408.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42QTE@68525|delta/epsilon subdivisions,2YR90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_63719_2	525898.Sdel_1998	5.8e-167	469.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42QX7@68525|delta/epsilon subdivisions,2YRDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_141165_1	765911.Thivi_0983	2.16e-118	350.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1WWUV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_202980_1	1122135.KB893135_gene982	3.52e-07	55.8	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,2U1IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
k59_156492_1	1168034.FH5T_11845	1.23e-17	77.8	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_156492_2	1168034.FH5T_11850	3.21e-141	415.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,2FM3Y@200643|Bacteroidia	976|Bacteroidetes	F	Class II glutamine amidotransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
k59_195252_1	1317122.ATO12_04935	2.83e-104	339.0	COG1028@1|root,COG3321@1|root,COG4221@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia,2YGKF@290174|Aquimarina	976|Bacteroidetes	IQ	PKS_DH	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_63725_1	1123326.JFBL01000014_gene240	2.43e-47	177.0	COG3209@1|root,COG3209@2|Bacteria,1R0C4@1224|Proteobacteria,43CUG@68525|delta/epsilon subdivisions,2YSH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_125684_1	566466.NOR53_923	1.56e-44	147.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1J6Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_241597_1	477974.Daud_0168	5.54e-105	324.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_187472_1	768671.ThimaDRAFT_3072	1.02e-11	63.9	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,1S4YC@1236|Gammaproteobacteria,1WYD8@135613|Chromatiales	135613|Chromatiales	Q	PFAM thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
k59_187472_2	1121035.AUCH01000002_gene1609	7.04e-25	102.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,2KVJW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_141181_1	1250006.JHZZ01000001_gene2921	7.54e-89	272.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1I15D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
k59_133269_1	1168034.FH5T_00375	2.62e-100	295.0	COG0349@1|root,COG0349@2|Bacteria,4NP3B@976|Bacteroidetes,2FN2U@200643|Bacteroidia	976|Bacteroidetes	L	3'-5' exonuclease	rnd	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
k59_71376_1	207954.MED92_02409	3.45e-91	280.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,1XHUV@135619|Oceanospirillales	135619|Oceanospirillales	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_7,Fer4_8,LUD_dom
k59_172080_1	391595.RLO149_c037000	2.63e-33	128.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_1940_1	1397528.Q671_14960	1.23e-115	343.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales	135619|Oceanospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_48347_1	1165841.SULAR_01648	1.63e-24	97.4	2AINN@1|root,31954@2|Bacteria,1NDHA@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_71381_1	1123401.JHYQ01000008_gene369	2.83e-48	166.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,460MK@72273|Thiotrichales	72273|Thiotrichales	M	Lipid A biosynthesis	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_195263_1	1168034.FH5T_00385	1.87e-46	165.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,2FMT4@200643|Bacteroidia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k59_195263_2	1408473.JHXO01000005_gene1652	7.91e-05	44.7	2AIA7@1|root,318R1@2|Bacteria,4NQPK@976|Bacteroidetes,2FPYF@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF5063
k59_234124_1	1121931.AUHG01000012_gene2875	5.89e-95	305.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_94812_1	1174528.JH992893_gene5767	2.24e-51	187.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,PP-binding,Thioesterase
k59_156507_1	706191.PANA_3874	2.5e-28	111.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,3VY7J@53335|Pantoea	1236|Gammaproteobacteria	K	Response regulator in two-component regulatory system with CpxA	cpxR	GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010810,GO:0019219,GO:0019222,GO:0030155,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07662,ko:K19610	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728,M00770	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_172086_1	86416.Clopa_1601	4.35e-15	74.7	29VAC@1|root,30GQG@2|Bacteria,1UGFG@1239|Firmicutes,24P9A@186801|Clostridia,36MG6@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1523
k59_241616_1	395493.BegalDRAFT_3105	1.22e-63	219.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,45ZTR@72273|Thiotrichales	72273|Thiotrichales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
k59_110162_1	1172190.M947_10460	3.47e-06	45.8	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	AAA_19,ParE_toxin,UvrD-helicase,UvrD_C
k59_110162_2	665956.HMPREF1032_03224	8.43e-49	156.0	2E3EN@1|root,32YDN@2|Bacteria,1VDEB@1239|Firmicutes,25FXN@186801|Clostridia,3WMJY@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
k59_226154_1	1408473.JHXO01000001_gene1977	2.14e-13	70.9	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_17254_1	545276.KB898728_gene171	1.23e-35	126.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,1S50T@1236|Gammaproteobacteria,1X0TJ@135613|Chromatiales	135613|Chromatiales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_102339_1	313596.RB2501_06050	2.46e-123	363.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HWYG@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_94817_2	948071.S4S2J9_9CAUD	6.12e-29	112.0	4QB79@10239|Viruses,4QX2S@35237|dsDNA viruses  no RNA stage,4QS2C@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86940_1	1500893.JQNB01000001_gene2575	4.4e-26	113.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_234133_1	211114.JOEF01000062_gene1838	2.82e-18	87.4	29WSC@1|root,30IDK@2|Bacteria,2H320@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159884_1	880070.Cycma_3448	1.48e-75	243.0	COG5421@1|root,COG5421@2|Bacteria,4NK89@976|Bacteroidetes,47U0X@768503|Cytophagia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_229355_2	1168034.FH5T_10415	6.49e-68	212.0	28MFD@1|root,2ZASV@2|Bacteria,4NH4N@976|Bacteroidetes,2FQXU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214095_1	1121937.AUHJ01000062_gene1202	8.7e-115	337.0	COG1409@1|root,COG1409@2|Bacteria,1NI34@1224|Proteobacteria,1S397@1236|Gammaproteobacteria,46AR6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_237366_1	1168034.FH5T_14500	1.43e-118	348.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,2FMVX@200643|Bacteroidia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_43881_1	686340.Metal_2133	3.27e-37	144.0	COG2373@1|root,COG2931@1|root,COG3210@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XFUS@135618|Methylococcales	135618|Methylococcales	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_229366_2	1268237.G114_16380	1.18e-14	76.6	2DPBK@1|root,331E1@2|Bacteria,1NCT1@1224|Proteobacteria,1SSKK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5338_1	1280001.BAOA01000077_gene3114	4.28e-33	125.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1XT6K@135623|Vibrionales	135623|Vibrionales	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_5338_2	2340.JV46_10150	4.36e-44	148.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_136617_1	1173027.Mic7113_0733	1.36e-72	243.0	COG0745@1|root,COG2208@1|root,COG3452@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,SpoIIE
k59_74868_1	270374.MELB17_20856	4.72e-63	204.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,464H0@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_183237_2	3659.XP_004159983.1	5.88e-112	324.0	298BV@1|root,2RFCF@2759|Eukaryota,37JP6@33090|Viridiplantae,3GEH6@35493|Streptophyta,4JSPJ@91835|fabids	35493|Streptophyta	C	ATP synthase protein MI25-like	atp4	-	-	-	-	-	-	-	-	-	-	-	Mt_ATP-synt_B
k59_183237_3	3880.AES75379	6.96e-42	145.0	KOG4669@1|root,KOG4669@2759|Eukaryota,388GJ@33090|Viridiplantae,3GX83@35493|Streptophyta,4JURQ@91835|fabids	35493|Streptophyta	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	-	-	-	-	-	-	-	-	-	Mt_ATP-synt_B,Oxidored_q2
k59_113494_1	1250232.JQNJ01000001_gene1974	1.5e-55	176.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1I170@117743|Flavobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_159893_1	1116472.MGMO_1c00020	1.56e-26	113.0	COG3209@1|root,COG3292@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3292@2|Bacteria,COG3391@2|Bacteria,1MVV1@1224|Proteobacteria,1RY7B@1236|Gammaproteobacteria,1XGYX@135618|Methylococcales	135618|Methylococcales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_198897_1	1206777.B195_02613	2.77e-35	139.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1Z5E4@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	Penicillin-binding protein OB-like domain	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_221853_1	1249627.D779_1729	2.94e-109	317.0	COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,1RXZV@1236|Gammaproteobacteria,1WWCC@135613|Chromatiales	135613|Chromatiales	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k59_175217_1	502025.Hoch_4388	4.3e-13	75.5	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,42SFA@68525|delta/epsilon subdivisions,2WUV2@28221|Deltaproteobacteria,2YVKJ@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_12800_1	1122201.AUAZ01000006_gene3867	2.07e-05	52.8	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZS5@1236|Gammaproteobacteria,4676G@72275|Alteromonadaceae	1236|Gammaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,SBP_bac_3
k59_175223_1	1174684.EBMC1_12210	2.63e-62	207.0	COG2373@1|root,COG2373@2|Bacteria,1QXEG@1224|Proteobacteria,2TX94@28211|Alphaproteobacteria,2K8XX@204457|Sphingomonadales	204457|Sphingomonadales	C	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
k59_74889_1	1249627.D779_2911	5.1e-81	268.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales	135613|Chromatiales	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_5353_1	1157490.EL26_14575	1.51e-26	109.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,279SH@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_9
k59_121757_1	1323663.AROI01000003_gene2179	6.76e-19	86.7	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria	1224|Proteobacteria	V	(ABC) transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_245257_1	1208321.D104_10445	5.14e-64	209.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1R97Q@1224|Proteobacteria,1RRDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_121759_2	267608.RSc1700	1.44e-24	97.4	COG4678@1|root,COG4678@2|Bacteria,1R92U@1224|Proteobacteria,2VUZ6@28216|Betaproteobacteria,1K9F9@119060|Burkholderiaceae	28216|Betaproteobacteria	G	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	Phage_lysozyme
k59_206502_1	326424.FRAAL4897	2.9e-11	67.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4ERMB@85013|Frankiales	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_191245_1	713586.KB900536_gene369	7.35e-45	157.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
k59_214336_7	1040982.AXAL01000015_gene2402	1.59e-07	57.4	2AMF5@1|root,31CAN@2|Bacteria,1P9QS@1224|Proteobacteria,2UYFM@28211|Alphaproteobacteria,43QR1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175499_2	909663.KI867150_gene1310	5.05e-32	121.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,42Y9C@68525|delta/epsilon subdivisions,2WUJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_98361_1	1304885.AUEY01000006_gene732	7.7e-65	205.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria,2MIFR@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ATP_bind_3
k59_214342_1	1165841.SULAR_05613	7.62e-110	323.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2YMBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_183558_1	1046714.AMRX01000006_gene2653	1.28e-10	63.2	28K38@1|root,2Z9SF@2|Bacteria,1R916@1224|Proteobacteria,1S074@1236|Gammaproteobacteria,469IY@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_183558_2	1167006.UWK_02936	7.27e-50	175.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2WIJ0@28221|Deltaproteobacteria,2MITQ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_44181_1	1168034.FH5T_21255	2.92e-203	577.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,2FW8B@200643|Bacteroidia	976|Bacteroidetes	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_237644_1	589865.DaAHT2_1740	1.29e-19	87.8	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42PJ3@68525|delta/epsilon subdivisions,2WJF6@28221|Deltaproteobacteria,2MJ4S@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,OmpA
k59_175512_1	65393.PCC7424_2021	2.17e-28	118.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,3KJDH@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
k59_28677_1	1165841.SULAR_03757	3.34e-23	97.8	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_28677_2	1165841.SULAR_03752	5.96e-82	259.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2YNMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_152396_2	1123053.AUDG01000008_gene3677	9.71e-15	73.6	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_222171_1	1448139.AI20_11020	2.19e-20	93.2	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_28682_1	1499967.BAYZ01000035_gene1060	7.78e-72	232.0	COG1032@1|root,COG1032@2|Bacteria,2NQAV@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_214356_2	2340.JV46_06610	4.24e-96	298.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_113778_1	1168034.FH5T_07285	1.4e-07	57.4	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,2FTZD@200643|Bacteroidia	976|Bacteroidetes	S	Gliding motility-associated protein, GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
k59_113778_2	997884.HMPREF1068_04124	3e-06	48.9	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,2FNU8@200643|Bacteroidia,4AM6W@815|Bacteroidaceae	976|Bacteroidetes	S	GldM C-terminal domain	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
k59_51872_2	880070.Cycma_3934	4.15e-61	203.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_214363_2	1168034.FH5T_12395	3.52e-21	89.7	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,2FM2B@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_222178_1	395493.BegalDRAFT_2461	9.46e-34	130.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4623I@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CcmF_C,Cytochrom_C_asm
k59_222178_2	522306.CAP2UW1_0722	2.43e-41	144.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,1KQKF@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
k59_28689_1	1168034.FH5T_21800	1.77e-95	290.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,2FMTF@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
k59_105800_1	742823.HMPREF9465_00123	3.29e-12	71.6	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,4PQGT@995019|Sutterellaceae	28216|Betaproteobacteria	M	Transglycosylase SLT domain	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_129408_1	234267.Acid_3148	1.64e-18	84.3	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_191261_1	1168034.FH5T_13075	3.08e-28	110.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase C1-like family	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
k59_191261_2	1168034.FH5T_13080	5.79e-36	130.0	2C23X@1|root,31B63@2|Bacteria,4NS2W@976|Bacteroidetes,2FT67@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75234_1	765912.Thimo_0707	1.51e-194	560.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_214379_1	717231.Flexsi_0440	8.89e-54	181.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_191271_1	1301098.PKB_1989	2.95e-28	120.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_90487_1	1340493.JNIF01000003_gene2535	1.95e-49	176.0	COG5267@1|root,COG5267@2|Bacteria,3Y342@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_136931_2	313598.MED152_00420	0.000342	42.7	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia,3VVFF@52959|Polaribacter	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_51895_1	1165841.SULAR_01345	6.96e-193	561.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_39830_1	1517416.IDAT_05705	3.73e-28	107.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S69B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	general secretion pathway protein	gspG_2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_240791_1	395493.BegalDRAFT_0431	4.61e-77	254.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,45ZMV@72273|Thiotrichales	72273|Thiotrichales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2,OstA_C
k59_47543_1	555779.Dthio_PD0052	7.87e-31	127.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MGHZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_47543_2	202752.JL53_14330	1.38e-15	78.6	COG1484@1|root,COG1484@2|Bacteria,1TS3R@1239|Firmicutes,4HDHZ@91061|Bacilli,26KX9@186820|Listeriaceae	91061|Bacilli	L	Pfam PF01695	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_70624_1	2340.JV46_03620	1.11e-133	392.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1J4Z9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_32230_1	1506583.JQJY01000010_gene1143	0.000292	48.5	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
k59_147980_1	1165841.SULAR_02113	1.17e-77	235.0	COG1040@1|root,COG1040@2|Bacteria,1Q1C2@1224|Proteobacteria,42T93@68525|delta/epsilon subdivisions,2YPEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transformation system protein	ctsW	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
k59_24205_1	395493.BegalDRAFT_3249	4.23e-79	244.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,1RRUD@1236|Gammaproteobacteria,461EB@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
k59_163536_1	272134.KB731324_gene5681	9.79e-37	142.0	COG1672@1|root,COG1672@2|Bacteria,1G2YT@1117|Cyanobacteria,1H8BR@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
k59_117187_1	936573.HMPREF1147_2295	1.36e-90	281.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,4H2XK@909932|Negativicutes	909932|Negativicutes	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_117187_2	2340.JV46_28140	9.01e-27	109.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1J547@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iEC042_1314.EC042_2616	tRNA-synt_1c
k59_1075_2	1165841.SULAR_09929	1.73e-206	574.0	COG2857@1|root,COG2857@2|Bacteria,1PX4N@1224|Proteobacteria,42MFF@68525|delta/epsilon subdivisions,2YMBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ubiquinol cytochrome c oxidoreductase, cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	iIT341.HP1538	Cytochrom_C,Cytochrom_C1
k59_24215_1	1267211.KI669560_gene1040	9.67e-19	80.9	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1IT1Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_48006_1	1123248.KB893317_gene4393	1.18e-35	141.0	COG1020@1|root,COG1020@2|Bacteria,4NDV5@976|Bacteroidetes,1IPHG@117747|Sphingobacteriia	976|Bacteroidetes	Q	amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_31,PP-binding,Thioesterase
k59_40326_1	1499684.CCNP01000021_gene2740	3.89e-05	50.8	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,36G1Z@31979|Clostridiaceae	186801|Clostridia	J	Threonyl alanyl tRNA synthetase SAD	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_156203_1	393283.XP_007826779.1	1.19e-06	55.5	COG0666@1|root,KOG4177@2759|Eukaryota,3ANG6@33154|Opisthokonta,3PF88@4751|Fungi,3R3WJ@4890|Ascomycota,21EW5@147550|Sordariomycetes	4751|Fungi	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
k59_225880_1	314278.NB231_06166	4.79e-15	79.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_16913_1	1415778.JQMM01000001_gene1566	2.03e-59	197.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1J4C1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	histidyl-tRNA synthetase	hisS	GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358	HGTP_anticodon,tRNA-synt_His
k59_24725_1	941449.dsx2_0465	2.77e-42	154.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,42M1Z@68525|delta/epsilon subdivisions,2WJYC@28221|Deltaproteobacteria,2M7YP@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_1630_2	999541.bgla_1g27820	1.86e-49	165.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,1K0K6@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_202674_1	398512.JQKC01000068_gene4276	1.92e-18	90.9	COG3385@1|root,COG3385@2|Bacteria,1UZPH@1239|Firmicutes,24GAB@186801|Clostridia,3WNRD@541000|Ruminococcaceae	186801|Clostridia	L	Domain of unknown function (DUF4372)	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4372
k59_225891_2	65393.PCC7424_5877	2.38e-34	128.0	COG3335@1|root,COG3335@2|Bacteria,1G06Q@1117|Cyanobacteria,3KKQ2@43988|Cyanothece	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_Tnp_IS630
k59_1631_1	616991.JPOO01000003_gene337	1.32e-102	306.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,23I5E@178469|Arenibacter	976|Bacteroidetes	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_1631_2	398720.MED217_15065	1e-30	112.0	COG2963@1|root,COG2963@2|Bacteria,4NRTR@976|Bacteroidetes,1I3TE@117743|Flavobacteriia	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_225894_1	1168034.FH5T_02755	8.36e-77	246.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,2FSAD@200643|Bacteroidia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_24734_1	317025.Tcr_0123	1.17e-80	249.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,45ZXW@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_233771_1	1165841.SULAR_03662	2.55e-73	232.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_218239_1	1178825.ALIH01000010_gene379	1.61e-15	81.6	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_148440_1	1313172.YM304_17920	2.01e-16	83.6	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4CNN2@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_156217_1	1004149.AFOE01000041_gene1192	7.41e-136	399.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_156217_2	991.IW20_03840	2.39e-40	147.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia,2NSEQ@237|Flavobacterium	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_163989_1	203124.Tery_0546	2.37e-14	77.8	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1G1P1@1117|Cyanobacteria,1H8EM@1150|Oscillatoriales	1117|Cyanobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_241284_1	1499967.BAYZ01000117_gene3317	2.16e-92	286.0	COG1178@1|root,COG1178@2|Bacteria	2|Bacteria	P	thiamine transport	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_78953_1	118163.Ple7327_3963	2.61e-52	184.0	2BXCB@1|root,2Z8QU@2|Bacteria	2|Bacteria	M	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers	phaZ2	-	3.1.1.22	ko:K07518	ko00650,map00650	-	R00048	RC00037,RC00094	ko00000,ko00001,ko01000	-	-	-	3HBOH
k59_187195_1	1168034.FH5T_06920	1e-82	267.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,2G2YH@200643|Bacteroidia	976|Bacteroidetes	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_171781_1	395493.BegalDRAFT_3038	3.7e-07	52.4	COG2703@1|root,COG2703@2|Bacteria,1MZJ3@1224|Proteobacteria,1SEKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_1650_1	1168034.FH5T_14990	7.14e-82	255.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,2G2YY@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
k59_148443_1	1047013.AQSP01000115_gene361	4.1e-29	119.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_78969_1	1123072.AUDH01000001_gene2830	3.3e-34	126.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,2JQ6S@204441|Rhodospirillales	204441|Rhodospirillales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_210368_1	1134474.O59_003251	2.68e-23	97.8	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1FGVM@10|Cellvibrio	1236|Gammaproteobacteria	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k59_63422_1	1165841.SULAR_06328	9.15e-157	462.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_233793_1	1004149.AFOE01000007_gene1298	9.41e-110	340.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IJ8N@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_218260_1	1333856.L686_06050	2.25e-67	212.0	28HAW@1|root,2Z7N4@2|Bacteria,1R5JH@1224|Proteobacteria,1RZWN@1236|Gammaproteobacteria,1Z2PT@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	KilA-N	-	-	-	-	-	-	-	-	-	-	-	-	KilA-N
k59_171791_1	1168289.AJKI01000007_gene209	5e-42	139.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,3XK95@558415|Marinilabiliaceae	976|Bacteroidetes	L	bacterial (prokaryotic) histone like domain	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_171791_2	1168034.FH5T_01195	4.57e-34	122.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,2FSSX@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_78977_2	1201293.AKXQ01000013_gene3721	7.66e-58	187.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_3,PAS,Response_reg
k59_233795_1	1137799.GZ78_17130	5.87e-37	143.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1XHEA@135619|Oceanospirillales	135619|Oceanospirillales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_16952_1	379066.GAU_0665	2.65e-36	136.0	COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_187215_1	1392498.JQLH01000001_gene874	1.49e-84	253.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia,2PH97@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_171794_2	1179778.PMM47T1_07721	3.7e-09	58.9	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_140880_1	1237149.C900_05403	5.71e-07	56.6	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
k59_71112_1	768671.ThimaDRAFT_2736	2.03e-30	110.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales	135613|Chromatiales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_71112_2	745014.OMB55_00001730	1.59e-10	62.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_218269_1	342610.Patl_1687	1.07e-77	246.0	COG0520@1|root,COG0520@2|Bacteria,1R4SM@1224|Proteobacteria,1RQR6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Class V aminotransferase	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_241310_1	102232.GLO73106DRAFT_00008940	6.2e-60	199.0	COG0446@1|root,COG0446@2|Bacteria,1GAC6@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_241312_2	545276.KB898732_gene2472	4.45e-51	169.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1WXG2@135613|Chromatiales	135613|Chromatiales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94502_1	1165841.SULAR_01455	7.02e-179	512.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_9472_1	1122137.AQXF01000004_gene1506	3.43e-39	147.0	COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2U11H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
k59_9472_2	665029.EAMY_1759	8.13e-55	181.0	28PDP@1|root,2ZC5M@2|Bacteria,1RB40@1224|Proteobacteria,1S2HG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_164033_1	313596.RB2501_05610	2.56e-109	332.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia	976|Bacteroidetes	P	Chloride channel protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_156264_1	870187.Thini_2202	4.2e-10	59.3	COG1309@1|root,COG1309@2|Bacteria,1RHNC@1224|Proteobacteria,1SB4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_102115_1	519989.ECTPHS_02349	3.85e-51	168.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1WXJF@135613|Chromatiales	135613|Chromatiales	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_48055_1	32057.KB217478_gene5843	4.33e-106	322.0	COG1524@1|root,COG3379@1|root,COG1524@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Phosphodiest,TPR_19
k59_109914_1	1411685.U062_01800	9.27e-28	107.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1J4ZN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	COG1428 Deoxynucleoside kinases	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
k59_109914_2	1158182.KB905021_gene428	1.13e-20	87.8	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1WYQM@135613|Chromatiales	135613|Chromatiales	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_225946_1	247634.GPB2148_2431	5.7e-57	191.0	COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria,1JAQT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
k59_66302_1	1123355.JHYO01000008_gene2684	1.34e-70	222.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,36XHC@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_143852_1	1165841.SULAR_01270	1.28e-110	349.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_236632_1	1168034.FH5T_00385	5.32e-131	390.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,2FMT4@200643|Bacteroidia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k59_50716_1	1535287.JP74_03920	2.08e-26	108.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSBR@28211|Alphaproteobacteria,3N834@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_135921_1	1385514.N782_06580	7.96e-24	101.0	COG1099@1|root,COG1099@2|Bacteria,1UXNI@1239|Firmicutes,4HGRF@91061|Bacilli,2YB84@289201|Pontibacillus	91061|Bacilli	S	with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_228686_1	686340.Metal_2040	2.28e-40	153.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,1S1Y0@1236|Gammaproteobacteria,1XEI1@135618|Methylococcales	135618|Methylococcales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_74040_1	933262.AXAM01000009_gene1481	3.68e-110	326.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria,2MHKP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_28043_1	314232.SKA53_03609	0.000596	46.2	COG0653@1|root,COG3318@1|root,COG0653@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2U3DY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	SEC-C motif	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
k59_128756_1	305700.B447_14449	2.05e-20	87.8	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2VMVW@28216|Betaproteobacteria,2KW3A@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k59_113118_1	452637.Oter_0527	1.61e-26	110.0	COG1505@1|root,COG1505@2|Bacteria,46SRT@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_205968_1	392500.Swoo_1491	4.64e-13	65.5	2FJR7@1|root,34BE3@2|Bacteria,1NZYT@1224|Proteobacteria,1SSMN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136289_1	1165841.SULAR_06918	7.58e-75	232.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2YMK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_136289_2	1165841.SULAR_06928	3.77e-19	80.5	COG1399@1|root,COG1399@2|Bacteria,1Q1I8@1224|Proteobacteria,42TRP@68525|delta/epsilon subdivisions,2YQ23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_198446_1	318167.Sfri_3808	3.04e-13	69.3	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,2Q95Z@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_229044_1	243265.plu3469	3.7e-25	107.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1NEHF@1224|Proteobacteria,1RMJ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Peptidase_M78
k59_237074_1	1121875.KB907555_gene358	3.47e-67	223.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_43528_1	1123020.AUIE01000041_gene3209	1.58e-42	152.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1YEG6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_121118_1	387093.SUN_1812	1.28e-25	102.0	COG3869@1|root,COG3869@2|Bacteria,1R4ST@1224|Proteobacteria,42MP2@68525|delta/epsilon subdivisions,2YNUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP:guanido phosphotransferase, N-terminal domain	-	-	2.7.3.2,2.7.3.3	ko:K00933,ko:K00934	ko00330,ko01100,map00330,map01100	M00047	R00554,R01881	RC00002,RC00203	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ATP-gua_Ptrans,ATP-gua_PtransN
k59_121118_2	387093.SUN_1807	2.16e-57	185.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_97720_1	1109445.AGSX01000186_gene2365	4.3e-06	52.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1Z1BZ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	permease	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_159517_1	1031288.AXAA01000005_gene2114	2.19e-16	76.3	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,36ECT@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
k59_159517_2	1168034.FH5T_11300	9.73e-29	114.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,2FMR0@200643|Bacteroidia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_237080_2	396588.Tgr7_0088	2.9e-72	224.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1WWX9@135613|Chromatiales	135613|Chromatiales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_5034_1	2340.JV46_27580	9.41e-19	84.7	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	ttrA	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K08357,ko:K21307	ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020	-	R10149,R10150,R11487	RC00168,RC02823,RC03109	ko00000,ko00001,ko01000,ko02000	5.A.3.10,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_5034_2	2340.JV46_27590	6.98e-128	365.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1J9UJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7,Molydop_binding
k59_144394_1	1122197.ATWI01000016_gene2163	3.38e-61	197.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,4654U@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	iECBD_1354.ECBD_3445,iECOK1_1307.ECOK1_0175,iECSE_1348.ECSE_0173,iECW_1372.ECW_m0170,iEKO11_1354.EKO11_3744,iEcDH1_1363.EcDH1_3429,iEcE24377_1341.EcE24377A_0178,iEcHS_1320.EcHS_A0176,iNRG857_1313.NRG857_00890,iSFV_1184.SFV_0157,iUMN146_1321.UM146_23675,iUMNK88_1353.UMNK88_178,iWFL_1372.ECW_m0170,iY75_1357.Y75_RS00880	Prenyltransf
k59_121125_1	1232410.KI421421_gene3398	7.96e-30	114.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,43SH1@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PhoU domain	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_113131_2	272123.Anacy_3279	4.57e-52	168.0	COG2402@1|root,COG2402@2|Bacteria,1G6UZ@1117|Cyanobacteria,1HPSM@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
k59_128767_1	237727.NAP1_14638	2.29e-33	134.0	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,2TW3Y@28211|Alphaproteobacteria,2KEA5@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_182850_2	1165841.SULAR_06628	8.79e-72	218.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_159524_1	626887.J057_05751	9.26e-83	253.0	COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,1S22U@1236|Gammaproteobacteria,469TG@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_20023_1	387093.SUN_0517	9.23e-54	181.0	COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,43DZE@68525|delta/epsilon subdivisions,2YRGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
k59_20023_2	1165841.SULAR_08879	8.85e-43	152.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2YS4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
k59_58884_1	395493.BegalDRAFT_3092	2.42e-90	281.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,460A8@72273|Thiotrichales	72273|Thiotrichales	NU	Secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_190598_1	161934.XP_010692517.1	3.24e-14	73.2	COG1132@1|root,COG2801@1|root,KOG0017@2759|Eukaryota,KOG0055@2759|Eukaryota,37SFN@33090|Viridiplantae,3GFGY@35493|Streptophyta	35493|Streptophyta	Q	ABC transporter B family member	-	-	3.6.3.44	ko:K05658	ko02010,ko04976,ko05206,ko05226,map02010,map04976,map05206,map05226	-	-	-	ko00000,ko00001,ko01000,ko02000,ko04090,ko04147	3.A.1.201	-	-	ABC_membrane,ABC_tran
k59_190598_2	3827.XP_004516035.1	3.36e-17	82.8	COG2801@1|root,KOG0017@2759|Eukaryota,388SY@33090|Viridiplantae,3GND2@35493|Streptophyta	35493|Streptophyta	L	DNA RNA polymerases superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	RVP_2,Retrotrans_gag,zf-CCHC
k59_198456_1	658187.LDG_7585	2.89e-136	394.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1JDF5@118969|Legionellales	118969|Legionellales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_198456_2	493475.GARC_1293	8.36e-35	121.0	COG2963@1|root,COG2963@2|Bacteria,1N2T5@1224|Proteobacteria,1S6PQ@1236|Gammaproteobacteria,46CXP@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_51145_1	1165841.SULAR_00720	7.41e-109	318.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2YN34@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_105213_1	879212.DespoDRAFT_00365	7.37e-31	127.0	COG0790@1|root,COG0790@2|Bacteria,1NQSN@1224|Proteobacteria,42YSM@68525|delta/epsilon subdivisions,2X3SW@28221|Deltaproteobacteria,2MMUZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159531_1	1165841.SULAR_01958	8.98e-97	295.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_12478_1	1238450.VIBNISOn1_1160062	6.57e-27	103.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	gstF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1,GST_C,GST_N_3
k59_12478_2	1122138.AQUZ01000029_gene4749	4.53e-16	75.5	COG0640@1|root,COG0640@2|Bacteria,2IS00@201174|Actinobacteria,4DW8A@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_136302_1	49964.Q94MR7_9CAUD	2.03e-67	228.0	4QERB@10239|Viruses,4R014@35237|dsDNA viruses  no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182857_1	870187.Thini_4370	5.62e-81	263.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RS9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_159532_1	1165841.SULAR_02268	1.23e-138	400.0	COG2200@1|root,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_51152_1	926569.ANT_19660	1.13e-12	70.1	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_128783_1	1121937.AUHJ01000021_gene1432	7.88e-99	295.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,46BKC@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_97741_1	1075090.GOAMR_19_00280	1.18e-19	86.7	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4GBT2@85026|Gordoniaceae	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k59_205995_2	1123514.KB905899_gene1198	3.13e-33	127.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,463MS@72273|Thiotrichales	72273|Thiotrichales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_159544_1	266264.Rmet_0239	2.42e-16	79.3	2C5U9@1|root,318BZ@2|Bacteria,1RK4D@1224|Proteobacteria,2VTKM@28216|Betaproteobacteria,1KH46@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
k59_128794_1	1049564.TevJSym_bc00360	1.04e-35	130.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,1JB7M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_128794_2	768671.ThimaDRAFT_0143	5.25e-32	117.0	2DNYF@1|root,32ZSU@2|Bacteria,1N8ZB@1224|Proteobacteria,1S5ZH@1236|Gammaproteobacteria,1WYS0@135613|Chromatiales	135613|Chromatiales	S	PFAM HupH hydrogenase expression protein, C-terminal conserved region	-	-	-	ko:K03618	-	-	-	-	ko00000	-	-	-	HupH_C
k59_97748_1	261292.Nit79A3_3309	3.53e-79	246.0	COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,2WFID@28216|Betaproteobacteria,372P9@32003|Nitrosomonadales	28216|Betaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_82187_1	765912.Thimo_2947	3.36e-31	119.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1WWEJ@135613|Chromatiales	135613|Chromatiales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_144433_1	387093.SUN_1391	2.2e-10	64.3	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_36057_2	444861.E3SPM2_9CAUD	7.56e-92	288.0	4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses  no RNA stage,4QPJE@28883|Caudovirales	28883|Caudovirales	S	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_198493_1	4113.PGSC0003DMT400024853	8.33e-09	57.0	2ESJY@1|root,2SV48@2759|Eukaryota,381J0@33090|Viridiplantae,3GQNG@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5055_1	551789.ATVJ01000001_gene2095	1.75e-62	201.0	COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,2VEUG@28211|Alphaproteobacteria,43XTK@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	gstR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_136318_1	497321.C664_04996	1.28e-64	201.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2VT25@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_244728_2	1121904.ARBP01000010_gene2255	6.02e-25	100.0	28HMY@1|root,2Z7WC@2|Bacteria,4NG8W@976|Bacteroidetes,47Q27@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_198495_1	2340.JV46_28500	5.49e-152	436.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1J5B3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_82198_1	1300345.LF41_1239	3.72e-41	147.0	COG4700@1|root,COG4700@2|Bacteria,1R577@1224|Proteobacteria,1S5I8@1236|Gammaproteobacteria,1X5VW@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
k59_97761_1	477184.KYC_14747	1.14e-31	120.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,3T1K8@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_101417_2	445696.E3ST05_9CAUD	2.63e-96	296.0	4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses  no RNA stage,4QQ4N@28883|Caudovirales,4QIBN@10662|Myoviridae	10662|Myoviridae	S	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_233029_1	387093.SUN_0205	1.51e-33	120.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2YNYN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin synthase alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_233029_2	697282.Mettu_4118	3.82e-08	54.3	COG3837@1|root,COG3837@2|Bacteria,1R0Y0@1224|Proteobacteria,1T54B@1236|Gammaproteobacteria,1XH1S@135618|Methylococcales	135618|Methylococcales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_233029_3	1165841.SULAR_09959	3.96e-118	343.0	COG4121@1|root,COG4121@2|Bacteria,1Q8T8@1224|Proteobacteria,42RAP@68525|delta/epsilon subdivisions,2YP3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_155601_1	77586.LPERR01G03130.1	7.78e-18	83.2	COG0173@1|root,KOG2411@2759|Eukaryota,37R5P@33090|Viridiplantae,3GB23@35493|Streptophyta,3KXTQ@4447|Liliopsida,3IFQS@38820|Poales	35493|Streptophyta	J	GAD domain	-	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_155601_2	1262915.BN574_01309	7.92e-24	102.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4H24X@909932|Negativicutes	909932|Negativicutes	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k59_209668_1	1123393.KB891326_gene144	8.01e-18	85.5	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k59_209668_2	765914.ThisiDRAFT_0268	6.99e-40	145.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,1RQ6N@1236|Gammaproteobacteria,1WWGR@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_217556_2	1121904.ARBP01000026_gene651	3.22e-29	117.0	COG0714@1|root,COG0714@2|Bacteria,4NGEG@976|Bacteroidetes,47NU2@768503|Cytophagia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
k59_163333_1	391613.RTM1035_17052	1.57e-12	66.6	COG4313@1|root,COG4313@2|Bacteria,1MXNW@1224|Proteobacteria,2TV0V@28211|Alphaproteobacteria,46NMS@74030|Roseovarius	28211|Alphaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,Phenol_MetA_deg
k59_147813_1	56107.Cylst_1153	5.32e-39	148.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GIES@1117|Cyanobacteria,1HJBM@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,Pkinase
k59_55083_1	404380.Gbem_0812	3.94e-39	142.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WPR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_47291_1	626887.J057_08786	8.8e-07	56.6	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_116970_1	301.JNHE01000023_gene2569	2.2e-05	45.1	COG5457@1|root,COG5457@2|Bacteria,1N9IB@1224|Proteobacteria,1TCG4@1236|Gammaproteobacteria,1YKAT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1127
k59_70431_1	1123504.JQKD01000002_gene4025	3.6e-72	238.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2VHFM@28216|Betaproteobacteria,4AA7W@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k59_47295_1	1168034.FH5T_11380	1.29e-71	227.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,2FNIX@200643|Bacteroidia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_217562_1	252305.OB2597_12396	1.39e-50	177.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,2PEZZ@252301|Oceanicola	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_8618_1	1151292.QEW_0616	4.68e-16	81.3	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,25RP8@186804|Peptostreptococcaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_233037_1	870187.Thini_1295	1.21e-75	253.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,4602H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_186556_1	1304874.JAFY01000002_gene148	8.15e-76	241.0	COG0577@1|root,COG0577@2|Bacteria,3TAB5@508458|Synergistetes	508458|Synergistetes	V	ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_225220_1	1165841.SULAR_03612	9.81e-55	176.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2YQ5A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_225220_2	944547.ABLL_2811	2.73e-19	82.4	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_78204_1	313596.RB2501_05570	1.22e-118	348.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_109135_1	1123487.KB892846_gene568	4.09e-06	48.9	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KU71@206389|Rhodocyclales	206389|Rhodocyclales	NU	type II secretion system protein	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_24010_1	1168034.FH5T_12260	2.48e-40	148.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_47305_1	1492738.FEM21_07470	2.34e-07	55.8	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1HY6W@117743|Flavobacteriia,2NS7E@237|Flavobacterium	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_163362_2	283942.IL0896	1.75e-22	90.9	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,2QGCZ@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
k59_163362_3	65093.PCC7418_2024	4.53e-09	56.6	COG2304@1|root,COG2304@2|Bacteria,1G1BE@1117|Cyanobacteria	1117|Cyanobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_147825_1	1089547.KB913013_gene1769	2.92e-11	69.7	COG3940@1|root,COG3940@2|Bacteria,4PKWP@976|Bacteroidetes,47MYK@768503|Cytophagia	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
k59_155621_1	1165841.SULAR_08467	1.47e-86	259.0	COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria	1224|Proteobacteria	M	COG3637 Opacity protein and related surface antigens	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
k59_124587_1	1004149.AFOE01000042_gene2772	1.18e-163	491.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_70446_1	392499.Swit_1277	1.39e-08	57.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2TSWT@28211|Alphaproteobacteria,2K1FN@204457|Sphingomonadales	204457|Sphingomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_70446_2	2340.JV46_05640	1.05e-25	95.5	2C7TU@1|root,32RJT@2|Bacteria,1N2CD@1224|Proteobacteria,1S96C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_178842_1	4081.Solyc01g007640.2.1	0.0	2309.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_178842_2	4081.Solyc01g007650.2.1	7.05e-41	135.0	2CQT8@1|root,2R5Q2@2759|Eukaryota,386GT@33090|Viridiplantae,3GUDY@35493|Streptophyta,44UFM@71274|asterids	35493|Streptophyta	S	Chloroplast protein precursor Ycf15 putative	-	-	-	-	-	-	-	-	-	-	-	-	Ycf15
k59_178842_3	3712.Bo5g098620.1	6.39e-07	49.3	2E7CP@1|root,2R1P8@2759|Eukaryota,383D7@33090|Viridiplantae,3GWXB@35493|Streptophyta,3I19M@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124592_1	1201293.AKXQ01000003_gene2462	1.57e-69	221.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,1S3RK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_147827_1	313603.FB2170_10319	1.97e-81	263.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1I4ES@117743|Flavobacteriia	976|Bacteroidetes	P	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
k59_895_1	1122619.KB892341_gene785	8.14e-111	342.0	COG3012@1|root,COG3012@2|Bacteria,1R5E5@1224|Proteobacteria,2VZMD@28216|Betaproteobacteria,3T744@506|Alcaligenaceae	28216|Betaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,SEC-C
k59_24015_2	426117.M446_0169	2.19e-53	180.0	COG3208@1|root,COG3208@2|Bacteria,1RGYT@1224|Proteobacteria,2U9ZM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase domain	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Thioesterase
k59_240626_2	1449063.JMLS01000011_gene313	3.88e-24	102.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Big_2,CBM_X2,CHB_HEX_C_1,F5_F8_type_C,FIVAR,Glyco_hyd_65N_2,Melibiase_2
k59_62776_1	5062.CADAORAP00009031	2.49e-11	69.7	KOG0266@1|root,KOG0266@2759|Eukaryota,38B6D@33154|Opisthokonta,3NZ4C@4751|Fungi,3QPCR@4890|Ascomycota,20AVS@147545|Eurotiomycetes,3S3IJ@5042|Eurotiales	4751|Fungi	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Helo_like_N,NACHT,WD40
k59_124596_1	317619.ANKN01000024_gene1584	1.21e-37	137.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
k59_132352_1	1094184.KWO_0103630	2.33e-27	105.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,1S9IF@1236|Gammaproteobacteria,1X7XN@135614|Xanthomonadales	135614|Xanthomonadales	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k59_31957_1	395493.BegalDRAFT_1600	2.95e-14	72.8	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31957_2	69279.BG36_22205	1.81e-14	72.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria,43NBU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_47317_1	1347342.BN863_24400	4.09e-41	150.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1HWMX@117743|Flavobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_16295_1	945550.VISI1226_03730	2.18e-06	52.8	COG2199@1|root,COG3706@2|Bacteria,1Q1G1@1224|Proteobacteria,1SB3J@1236|Gammaproteobacteria,1XU5R@135623|Vibrionales	135623|Vibrionales	T	GGDEF family	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_16295_2	1165841.SULAR_02483	1.16e-35	128.0	2DN4A@1|root,32VFK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70462_1	748247.AZKH_2696	7.34e-41	151.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2W9P9@28216|Betaproteobacteria,2KYVQ@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD binding domain	-	-	1.14.13.127,1.14.13.20	ko:K05712,ko:K10676	ko00360,ko00361,ko01100,ko01120,ko01220,map00360,map00361,map01100,map01120,map01220	M00545	R03997,R05441,R06786,R06787	RC00046,RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_70462_2	76114.ebA3298	8.72e-29	104.0	2E3JP@1|root,32YI0@2|Bacteria,1N6ZI@1224|Proteobacteria,2VWGY@28216|Betaproteobacteria,2KZ4N@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2783
k59_163378_1	2340.JV46_16600	2.2e-13	70.9	28JFR@1|root,2Z99N@2|Bacteria,1R7C5@1224|Proteobacteria,1RZYU@1236|Gammaproteobacteria,1JACI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_163378_2	631362.Thi970DRAFT_03109	6.5e-16	74.7	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1WXNV@135613|Chromatiales	135613|Chromatiales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_16301_1	1168034.FH5T_12410	7.65e-120	355.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FPY6@200643|Bacteroidia	976|Bacteroidetes	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
k59_147849_1	326298.Suden_0222	1.37e-80	254.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2YN29@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_194227_1	234267.Acid_6898	1.69e-64	211.0	COG3464@1|root,COG3464@2|Bacteria,3Y89T@57723|Acidobacteria	57723|Acidobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k59_910_1	1165841.SULAR_10279	2.42e-101	309.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_225252_1	1506994.JNLQ01000002_gene3551	1.33e-115	346.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,4BXNP@830|Butyrivibrio	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_24038_1	1283300.ATXB01000001_gene2341	2.49e-124	357.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_24038_2	1433126.BN938_0645	7.92e-15	75.1	COG3335@1|root,COG3335@2|Bacteria,4NGKZ@976|Bacteroidetes,2FXJB@200643|Bacteroidia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_140284_2	202952.BBLI01000015_gene1343	7.98e-10	65.5	COG4974@1|root,COG4974@2|Bacteria,1QUFQ@1224|Proteobacteria,1T1XD@1236|Gammaproteobacteria,3NN1Z@468|Moraxellaceae	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k59_62797_1	377629.TERTU_3359	7.76e-35	133.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,2PQ7K@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_62797_2	1163617.SCD_n01100	2.65e-15	76.6	COG2972@1|root,COG5001@1|root,COG2972@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKCJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,HAMP
k59_163674_1	1168034.FH5T_07040	6.65e-313	871.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,2FN30@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_86336_1	765912.Thimo_3175	3.52e-19	85.9	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_26643_2	1123367.C666_17100	2.18e-33	132.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2W1FU@28216|Betaproteobacteria,2KY41@206389|Rhodocyclales	206389|Rhodocyclales	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_96322_1	2340.JV46_15500	2.45e-36	125.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1J6HU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	conserved protein involved in intracellular sulfur reduction	tusD	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
k59_96322_2	2340.JV46_15490	2.63e-83	247.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1J7BW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the DsrF TusC family	tusC	GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
k59_96322_3	2340.JV46_15480	3.71e-13	64.3	COG2168@1|root,COG2168@2|Bacteria	2|Bacteria	P	tRNA wobble position uridine thiolation	tusB	GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
k59_57518_2	283699.D172_3703	1.53e-30	114.0	COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,1S9TC@1236|Gammaproteobacteria,2Q332@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	IspA
k59_119643_1	27923.ML25481a-PA	2.06e-05	52.8	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	1.14.19.41	ko:K09832	ko00100,ko01100,ko01110,map00100,map01100,map01110	-	R07489,R11097	RC01886	ko00000,ko00001,ko00199,ko01000	-	-	-	RVT_1,RVT_3,zf-RVT
k59_220198_1	1250232.JQNJ01000001_gene1924	0.00013	42.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
k59_220198_2	1121875.KB907550_gene822	2.97e-159	452.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_111929_1	243233.MCA3046	9.63e-05	43.5	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XE7N@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_111929_2	395493.BegalDRAFT_2257	9.31e-63	207.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,462IZ@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
k59_88508_1	406817.XNC1_3632	2.41e-109	328.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_134973_1	880070.Cycma_3559	2.34e-42	157.0	COG3119@1|root,COG3119@2|Bacteria,4P1A0@976|Bacteroidetes,47UC6@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF229)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_142869_1	264730.PSPPH_5139	3.61e-20	89.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S7MT@1236|Gammaproteobacteria,1Z67K@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	Transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
k59_142869_2	1151116.Q7S_01275	1.56e-07	52.4	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,3FFWQ@34037|Rahnella	1236|Gammaproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSF_1195.SF3422,iUTI89_1310.UTI89_C3903	PEPCK_ATP
k59_227742_1	987059.RBXJA2T_02812	1.06e-12	66.2	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,1KKW6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_111933_1	925409.KI911562_gene2744	2.03e-59	206.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_7,TPR_8
k59_227744_1	566466.NOR53_824	5.02e-42	157.0	COG4447@1|root,COG4447@2|Bacteria,1R6KJ@1224|Proteobacteria	1224|Proteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_119652_1	1198232.CYCME_2178	4.36e-86	263.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,45ZVH@72273|Thiotrichales	72273|Thiotrichales	H	PFAM MoeZ MoeB domain	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_243282_2	391735.Veis_1374	1.18e-06	52.8	COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,2VKYN@28216|Betaproteobacteria,4AAPY@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM porin Gram-negative type	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_73019_2	706587.Desti_1817	2.92e-06	47.8	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria,2MSK6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_235667_1	1165841.SULAR_08367	7.91e-67	206.0	COG0775@1|root,COG0775@2|Bacteria,1R9VR@1224|Proteobacteria,42RM2@68525|delta/epsilon subdivisions,2YP67@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_235667_2	1165841.SULAR_08372	1.2e-52	171.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2YMH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,NMO
k59_88515_1	313628.LNTAR_06724	3.04e-27	114.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_142874_1	530564.Psta_3337	6.29e-07	56.2	COG0515@1|root,COG0515@2|Bacteria,2J50A@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Serine threonine protein kinase-related	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,dCache_1
k59_18663_1	1392489.JPOL01000002_gene3024	2.58e-19	89.4	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia,2XK4J@283735|Leeuwenhoekiella	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_18663_2	980584.AFPB01000086_gene2507	3.27e-15	79.0	COG0702@1|root,COG0702@2|Bacteria,4PKHQ@976|Bacteroidetes,1IJ9C@117743|Flavobacteriia	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_119653_1	1304878.AUGD01000019_gene1146	1.6e-92	291.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TS14@28211|Alphaproteobacteria,3JV25@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_18666_1	411154.GFO_2921	1.17e-14	73.6	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_18666_2	1348583.ATLH01000001_gene3555	2.43e-38	143.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,1F9XS@104264|Cellulophaga	976|Bacteroidetes	M	PFAM TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_150342_2	1049564.TevJSym_bm00080	4.47e-143	404.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1J5NT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506	ADK,ADK_lid
k59_166083_1	485916.Dtox_0720	4.95e-05	45.4	COG2002@1|root,COG2002@2|Bacteria,1VP61@1239|Firmicutes,24WKE@186801|Clostridia,263CJ@186807|Peptococcaceae	186801|Clostridia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
k59_73024_1	631362.Thi970DRAFT_04371	6.59e-19	87.8	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_26662_2	1195246.AGRI_10696	2.92e-28	114.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4642R@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02481,ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_119657_1	1198232.CYCME_1141	7.31e-38	135.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,463TN@72273|Thiotrichales	72273|Thiotrichales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_243289_1	32057.KB217478_gene6093	2.9e-34	133.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1HIIV@1161|Nostocales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
k59_11281_1	395493.BegalDRAFT_2833	2.67e-93	290.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,45ZT2@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_111945_1	1131813.AQVT01000001_gene585	5.67e-19	90.5	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2TU6K@28211|Alphaproteobacteria,1JRQM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_103936_1	1168034.FH5T_15110	4.08e-84	269.0	COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,2FMJD@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase, S9A B C family, catalytic domain protein	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_166092_2	1116472.MGMO_173c00050	1.59e-07	53.5	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XE56@135618|Methylococcales	135618|Methylococcales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	-
k59_3648_2	1125699.HMPREF9194_00435	4.82e-13	68.2	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_235685_1	765911.Thivi_1828	5.34e-23	99.4	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
k59_235685_2	1123399.AQVE01000001_gene648	3.16e-14	66.2	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,463BR@72273|Thiotrichales	72273|Thiotrichales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_220234_1	1235803.C825_04060	3.53e-59	206.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,2G065@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_111952_1	1046724.KB889875_gene1755	1.02e-15	82.4	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,46AS5@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	exporter	VP0886	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_158216_1	1453500.AT05_04185	6.74e-50	162.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_18686_1	472759.Nhal_0526	8.37e-81	253.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales	135613|Chromatiales	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_18686_2	196367.JNFG01000033_gene7484	2.75e-14	67.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,1K96V@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0434 family	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
k59_227766_1	572477.Alvin_2853	3.56e-20	83.6	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1WYUA@135613|Chromatiales	135613|Chromatiales	G	Phosphotransferase System	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
k59_227766_2	667014.Thein_1406	5.78e-22	91.7	COG2893@1|root,COG2893@2|Bacteria,2GIID@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
k59_119667_2	4565.Traes_2AL_F52C84040.1	1.49e-128	367.0	COG0839@1|root,2S14H@2759|Eukaryota,389Z6@33090|Viridiplantae,3GX82@35493|Streptophyta,3MAU6@4447|Liliopsida	35493|Streptophyta	P	Belongs to the complex I subunit 6 family	NAD6	-	1.6.5.3	ko:K03884	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q3
k59_26678_1	697282.Mettu_3116	5.57e-67	214.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1XE9X@135618|Methylococcales	135618|Methylococcales	G	PFAM Carbohydrate purine kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_26678_2	1116472.MGMO_87c00020	7.93e-104	311.0	COG0561@1|root,COG0561@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria,1XEIB@135618|Methylococcales	135618|Methylococcales	S	TIGRFAM HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	S6PP
k59_204627_1	366602.Caul_1812	1.56e-20	99.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,2TTUH@28211|Alphaproteobacteria,2KJEV@204458|Caulobacterales	204458|Caulobacterales	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_235700_1	1323663.AROI01000014_gene120	3.73e-66	216.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,PAS_7,Usp
k59_18693_1	1122963.AUHB01000007_gene3597	5.15e-08	57.8	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,36XN5@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Domain of unknown function (DUF3333)	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_166115_1	983544.Lacal_0034	3.57e-65	201.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_135282_1	1107311.Q767_00925	1.25e-23	104.0	COG1887@1|root,COG1887@2|Bacteria,4NG8F@976|Bacteroidetes,1HZJY@117743|Flavobacteriia,2NTDI@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf,MGDG_synth
k59_57862_1	598659.NAMH_0580	1.21e-43	159.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_57862_2	1165841.SULAR_02923	2.2e-142	419.0	COG0068@1|root,COG0068@2|Bacteria,1NS2D@1224|Proteobacteria,42RUP@68525|delta/epsilon subdivisions,2YP7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hydE	-	-	-	-	-	-	-	-	-	-	-	-
k59_135284_2	316067.Geob_0853	7.04e-05	48.9	COG4191@1|root,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	fleS	-	2.7.13.3	ko:K07709,ko:K10942	ko02020,ko05111,map02020,map05111	M00499,M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8
k59_57866_1	1049564.TevJSym_bw00080	6.98e-73	233.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1J5FV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_235981_1	768671.ThimaDRAFT_0705	1.91e-62	210.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_212697_2	1541065.JRFE01000058_gene5641	1.02e-17	89.7	COG2812@1|root,COG2812@2|Bacteria,1G4SF@1117|Cyanobacteria,3VNKI@52604|Pleurocapsales	1117|Cyanobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_189472_1	1267535.KB906767_gene2698	2.56e-66	212.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria,2JIRU@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_150643_1	157783.LK03_01190	4.3e-50	181.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_104255_1	314278.NB231_13201	6.71e-43	152.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_207969_1	203124.Tery_2969	9.12e-14	70.1	COG2084@1|root,COG2084@2|Bacteria,1G3A6@1117|Cyanobacteria,1HAFH@1150|Oscillatoriales	1117|Cyanobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
k59_207969_2	203124.Tery_2970	1.28e-101	305.0	COG1181@1|root,COG1181@2|Bacteria,1G1R5@1117|Cyanobacteria,1HA9Q@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
k59_22210_1	395493.BegalDRAFT_1422	5.57e-94	301.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_45476_1	313596.RB2501_08345	4.7e-129	380.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_99851_1	1165841.SULAR_00135	7.47e-148	436.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_239042_1	143224.JQMD01000002_gene1614	1.84e-144	418.0	COG1621@1|root,COG1621@2|Bacteria,4NZWC@976|Bacteroidetes,1I797@117743|Flavobacteriia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_115164_1	530564.Psta_4118	2.02e-10	63.5	COG1520@1|root,COG1520@2|Bacteria,2IXQF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_192616_1	314345.SPV1_13619	1.77e-38	136.0	COG2862@1|root,COG2862@2|Bacteria,1RF1A@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_22216_1	313596.RB2501_07350	6.91e-73	223.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_230940_1	1165841.SULAR_01080	3.09e-74	248.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,42ZJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_176892_1	1120968.AUBX01000012_gene2905	2.86e-70	224.0	COG4099@1|root,COG4099@2|Bacteria,4PJN0@976|Bacteroidetes,47NYM@768503|Cytophagia	976|Bacteroidetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Peptidase_S9
k59_176892_2	869213.JCM21142_104410	8.41e-17	75.9	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,47R7Q@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_45489_1	7668.SPU_013402-tr	7.34e-36	140.0	2CMGD@1|root,2QQ9V@2759|Eukaryota,39B3J@33154|Opisthokonta,3BKG5@33208|Metazoa,3CTR5@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2
k59_61025_1	1278309.KB907109_gene3244	8.32e-61	192.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1XKMI@135619|Oceanospirillales	135619|Oceanospirillales	CO	Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_223550_1	78245.Xaut_4055	2.03e-43	160.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,3F0JX@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
k59_115170_1	1089550.ATTH01000001_gene2507	1.33e-12	73.2	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1FIS3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_169685_1	234267.Acid_6898	1.97e-30	125.0	COG3464@1|root,COG3464@2|Bacteria,3Y89T@57723|Acidobacteria	57723|Acidobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k59_123169_1	1265313.HRUBRA_02490	2.92e-93	297.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1J57N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_14384_1	767817.Desgi_4437	1.07e-10	58.5	COG1396@1|root,COG1396@2|Bacteria,1VFZE@1239|Firmicutes,24SFS@186801|Clostridia	186801|Clostridia	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
k59_161601_1	641491.DND132_2614	1.36e-28	114.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_14385_1	439235.Dalk_1773	1.75e-13	64.7	COG2161@1|root,COG2161@2|Bacteria,1N07B@1224|Proteobacteria,42UIW@68525|delta/epsilon subdivisions,2WQU3@28221|Deltaproteobacteria,2MKSY@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_30207_1	1172190.M947_03970	1.19e-100	308.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria,1MUGA@1224|Proteobacteria,42NI0@68525|delta/epsilon subdivisions,2YNKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP citrate synthase	-	-	2.3.3.8	ko:K15230	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,Ligase_CoA
k59_123173_1	2340.JV46_02600	1.36e-83	256.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1J4KG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_0109	QRPTase_C,QRPTase_N
k59_91790_1	1177181.T9A_03157	1.36e-41	153.0	COG1773@1|root,COG3239@1|root,COG1773@2|Bacteria,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Alkane 1-monooxygenase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase,Rubredoxin
k59_138237_1	1174528.JH992892_gene6509	1.55e-35	128.0	COG5433@1|root,COG5433@2|Bacteria,1G3Z6@1117|Cyanobacteria,1JJXX@1189|Stigonemataceae	1117|Cyanobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_192637_1	1178825.ALIH01000009_gene1260	6.25e-19	91.3	COG2273@1|root,COG3291@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_38059_1	1250232.JQNJ01000001_gene2136	5.19e-51	165.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
k59_223569_1	630626.EBL_c30660	4.89e-69	224.0	COG1857@1|root,COG1857@2|Bacteria,1MVNH@1224|Proteobacteria,1RMBZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	crispr-associated protein	cas7e	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
k59_6917_1	1479238.JQMZ01000001_gene1446	2.01e-50	177.0	COG0520@1|root,COG0520@2|Bacteria,1N124@1224|Proteobacteria,2TZXB@28211|Alphaproteobacteria,43ZHD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_230970_1	945550.VISI1226_02882	1.56e-35	131.0	COG1864@1|root,COG1864@2|Bacteria,1RADP@1224|Proteobacteria,1S30S@1236|Gammaproteobacteria,1XVI2@135623|Vibrionales	135623|Vibrionales	F	DNA RNA endonuclease G, NUC1	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
k59_107232_1	349124.Hhal_1900	6.37e-54	189.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1WVWQ@135613|Chromatiales	135613|Chromatiales	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_45508_1	1171373.PACID_15310	0.000337	48.9	2B5FX@1|root,31YAK@2|Bacteria,2GWPK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_head_fibr
k59_123183_1	547144.HydHO_0260	1.31e-13	67.0	COG0049@1|root,COG0049@2|Bacteria,2G3YX@200783|Aquificae	200783|Aquificae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_130775_1	1168034.FH5T_17095	1.77e-82	250.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,2FSCB@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_91798_1	754476.Q7A_332	1.96e-18	85.5	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,45ZQK@72273|Thiotrichales	72273|Thiotrichales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_91798_2	545264.KB898752_gene2359	1.16e-26	103.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1WY33@135613|Chromatiales	135613|Chromatiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_208003_1	631362.Thi970DRAFT_03639	1.51e-55	186.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RX39@1236|Gammaproteobacteria,1WXEH@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_230974_1	1168034.FH5T_09225	6.21e-42	145.0	COG0664@1|root,COG0664@2|Bacteria,4P3ES@976|Bacteroidetes,2FYTV@200643|Bacteroidia	976|Bacteroidetes	T	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_6926_2	1165841.SULAR_02683	4.8e-128	369.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,42QE2@68525|delta/epsilon subdivisions,2YNKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_176905_2	314285.KT71_03157	2.03e-174	504.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1JBW7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_223582_1	1165841.SULAR_00280	7.4e-154	444.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_45532_1	985054.JQEZ01000001_gene2869	6.93e-39	147.0	COG2114@1|root,COG4753@1|root,COG2114@2|Bacteria,COG4753@2|Bacteria,1PYP4@1224|Proteobacteria,2TVEP@28211|Alphaproteobacteria,4NCYJ@97050|Ruegeria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
k59_76600_1	1168034.FH5T_11580	2.78e-62	200.0	COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,2FN72@200643|Bacteroidia	976|Bacteroidetes	G	Kinase, PfkB family	ydjH_1	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_153787_1	1168034.FH5T_01685	3.56e-117	339.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,2FQ1J@200643|Bacteroidia	976|Bacteroidetes	I	CoA-transferase	scoB	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01029,ko:K01032,ko:K01035	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_53195_1	1165841.SULAR_03133	1.32e-79	245.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,42SFK@68525|delta/epsilon subdivisions,2YPP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_76603_1	1242864.D187_001187	2.56e-62	202.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_246612_1	870187.Thini_0481	4.23e-46	164.0	COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	50S ribosome-binding GTPase	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
k59_7342_1	1396858.Q666_10975	2.51e-13	72.8	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,4648Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_22634_1	395493.BegalDRAFT_1189	9.38e-15	72.4	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,1SH3A@1236|Gammaproteobacteria,463C1@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_22634_2	391615.ABSJ01000059_gene2138	3.4e-52	171.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1J4SJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E0035	DapB_C,DapB_N
k59_14776_1	1500301.JQMF01000007_gene1582	1.2e-40	152.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,4B97V@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_84459_1	1165841.SULAR_00230	3.74e-28	111.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_154181_1	1401065.HMPREF2130_00340	5.15e-11	68.2	COG3307@1|root,COG3307@2|Bacteria,1R8PC@1224|Proteobacteria,2VNKI@28216|Betaproteobacteria,3T90U@506|Alcaligenaceae	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
k59_45905_1	56110.Oscil6304_3489	5.48e-55	196.0	COG0515@1|root,COG0642@1|root,COG3899@1|root,COG4251@1|root,COG5002@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,Guanylate_cyc,HATPase_c,HisKA,HisKA_3,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE
k59_200866_1	1123355.JHYO01000016_gene1862	9.35e-132	387.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRII@28211|Alphaproteobacteria,36ZSI@31993|Methylocystaceae	28211|Alphaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_84470_1	1165841.SULAR_00710	6.78e-152	466.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_216057_1	1385514.N782_00950	2.35e-06	56.2	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,2Y8UT@289201|Pontibacillus	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_9
k59_138632_1	1168034.FH5T_11360	8.19e-135	397.0	COG1502@1|root,COG1502@2|Bacteria,4NE2W@976|Bacteroidetes,2FMEA@200643|Bacteroidia	976|Bacteroidetes	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_61398_1	1168034.FH5T_12500	1.31e-31	123.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_231353_2	58344.JOEL01000043_gene3187	1.01e-09	63.9	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria	201174|Actinobacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_22653_1	313596.RB2501_05270	1.56e-59	191.0	28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,1HZ05@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53566_1	1226325.HMPREF1548_06758	1.15e-05	52.4	COG3694@1|root,COG3694@2|Bacteria,1V0CD@1239|Firmicutes,248XM@186801|Clostridia,36KJH@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
k59_110965_1	1168034.FH5T_04795	6.16e-116	335.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,2FM46@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_80101_1	1165841.SULAR_09209	8.71e-137	393.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2YNCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0330	IlvC,IlvN
k59_203800_1	313603.FB2170_13613	2.75e-31	115.0	COG3279@1|root,COG3279@2|Bacteria,4NFN4@976|Bacteroidetes,1HYAZ@117743|Flavobacteriia,2PGVM@252356|Maribacter	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_203800_2	641526.ADIWIN_1573	3.2e-19	80.5	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1I21M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_87697_1	1196322.A370_02854	4.59e-46	167.0	COG0249@1|root,COG0249@2|Bacteria,1TPJP@1239|Firmicutes,247IW@186801|Clostridia,36DYT@31979|Clostridiaceae	186801|Clostridia	L	DNA mismatch repair protein MutS	mutS4	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
k59_72223_1	305700.B447_14259	8.95e-09	53.5	2EGR8@1|root,33AHD@2|Bacteria,1N6Z8@1224|Proteobacteria,2VVZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FeoC like transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FeoC
k59_72223_2	2340.JV46_09860	3.48e-39	146.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1J5MJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_118784_1	395493.BegalDRAFT_2928	3.64e-39	132.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,462JI@72273|Thiotrichales	72273|Thiotrichales	KT	PFAM Response regulator receiver domain	-	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_118784_2	395493.BegalDRAFT_2927	9.7e-72	216.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,462P6@72273|Thiotrichales	72273|Thiotrichales	KT	PFAM Response regulator receiver domain	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_196235_1	68170.KL590480_gene8688	1.09e-52	173.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4E1BI@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme	-	-	-	ko:K12239	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Nitroreductase,PP-binding
k59_180745_1	387093.SUN_2118	1.72e-66	215.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42MB3@68525|delta/epsilon subdivisions,2YN95@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
k59_110974_1	1165841.SULAR_07380	7.18e-97	301.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,42PUG@68525|delta/epsilon subdivisions,2YN09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB-dependent copper receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_211493_1	338966.Ppro_1891	1.12e-05	52.8	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA,VWA_2
k59_165265_1	1117647.M5M_00690	2.76e-06	49.3	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1JAJ1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_165265_2	1168034.FH5T_04100	9.9e-44	154.0	COG1073@1|root,COG1073@2|Bacteria,4NFCA@976|Bacteroidetes,2FP8B@200643|Bacteroidia	976|Bacteroidetes	S	PS-10 peptidase S37	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S37
k59_103181_1	1168034.FH5T_00055	4.52e-42	154.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,2FMXI@200643|Bacteroidia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase C-terminal	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_103181_2	675635.Psed_3712	1.04e-05	48.1	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4E13H@85010|Pseudonocardiales	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_203808_1	387093.SUN_1243	9.24e-86	267.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,43CEV@68525|delta/epsilon subdivisions,2YRH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_196240_1	395493.BegalDRAFT_2251	2.06e-78	252.0	COG2114@1|root,COG3447@1|root,COG2114@2|Bacteria,COG3447@2|Bacteria,1MW5Z@1224|Proteobacteria,1SZ7T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_172893_2	1538644.KO02_09795	0.000265	42.7	2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,1IUG5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118799_1	1385515.N791_04550	2.97e-74	239.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Activates fatty acids by binding to coenzyme A	rpfB	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_134128_1	1209072.ALBT01000039_gene188	9.96e-43	163.0	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1FH3X@10|Cellvibrio	1236|Gammaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_172895_1	313596.RB2501_05075	3.22e-136	395.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_165269_1	118173.KB235914_gene3477	2.39e-51	176.0	COG4941@1|root,COG4941@2|Bacteria,1G1YQ@1117|Cyanobacteria,1H7AG@1150|Oscillatoriales	1117|Cyanobacteria	K	RNA polymerase, sigma subunit, ECF family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_72243_1	395493.BegalDRAFT_2426	6.19e-49	174.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,1RSJ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
k59_72243_2	519989.ECTPHS_12024	1.47e-16	75.1	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1WZ2H@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
k59_87711_1	1056820.KB900640_gene286	2.1e-46	167.0	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,1RNZA@1236|Gammaproteobacteria,2PQ8W@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80110_1	1123487.KB892865_gene1365	9.17e-32	145.0	2ED18@1|root,336Y6@2|Bacteria,1NA4Q@1224|Proteobacteria,2W2NV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_219341_1	1165841.SULAR_07153	8.95e-127	390.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2YSXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
k59_172904_1	156889.Mmc1_2378	1.35e-37	142.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQTN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_219345_1	156889.Mmc1_2223	2.72e-52	176.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2U613@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Ubie_methyltran
k59_219345_2	243365.CV_3366	4.12e-07	50.8	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2VTX9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_D
k59_64572_1	4081.Solyc01g007640.2.1	5.42e-189	581.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_234951_1	1408473.JHXO01000001_gene1970	6.71e-19	85.1	COG2391@1|root,COG2391@2|Bacteria,4PJMC@976|Bacteroidetes,2FZGI@200643|Bacteroidia	976|Bacteroidetes	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
k59_25900_1	655815.ZPR_1910	0.000131	43.5	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1I2V8@117743|Flavobacteriia	976|Bacteroidetes	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_25900_2	313596.RB2501_12794	9.13e-99	307.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HY58@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_234957_1	1165841.SULAR_04487	3.58e-46	156.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2YNDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_234957_2	1165841.SULAR_04482	1.2e-57	192.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_149609_1	1193181.BN10_470023	7.2e-69	222.0	COG0189@1|root,COG0189@2|Bacteria,2I75I@201174|Actinobacteria,4FEMX@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
k59_49029_2	1089551.KE386572_gene1451	1.06e-16	82.4	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,4BPUM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Asparagine synthase	asnO	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_141945_1	1250232.JQNJ01000001_gene1557	1.8e-23	104.0	COG0457@1|root,COG4676@1|root,COG0457@2|Bacteria,COG4676@2|Bacteria,4NGJS@976|Bacteroidetes,1HWZQ@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_95597_1	313603.FB2170_03835	1.44e-81	254.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia,2PG0H@252356|Maribacter	976|Bacteroidetes	H	Elongator protein 3, MiaB family, Radical SAM	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_33916_1	595460.RRSWK_04262	5.17e-82	261.0	COG3119@1|root,COG3119@2|Bacteria,2J1TA@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_64586_1	313603.FB2170_11246	1.06e-103	312.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1HY02@117743|Flavobacteriia,2PG21@252356|Maribacter	976|Bacteroidetes	M	Glycosyl transferase family group 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
k59_2837_2	439235.Dalk_5256	1.18e-125	370.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MNIW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_49399_2	396588.Tgr7_2581	5.32e-37	131.0	28QMK@1|root,2ZD39@2|Bacteria,1RAWM@1224|Proteobacteria,1S2FU@1236|Gammaproteobacteria,1WY0Y@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_181130_1	1192034.CAP_0549	8.82e-30	124.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_95914_1	1278307.KB906990_gene3107	1.38e-83	257.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,2QITP@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Patatin-like phospholipase	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_34261_1	247634.GPB2148_1989	1.64e-26	101.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_34261_2	247634.GPB2148_3164	1.1e-43	144.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
k59_157768_1	90814.KL370891_gene810	2.15e-13	68.6	2AHEZ@1|root,317S6@2|Bacteria,1NHDD@1224|Proteobacteria,1SRTZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_157768_2	365044.Pnap_2746	1.32e-36	132.0	COG2378@1|root,COG2378@2|Bacteria,1R65H@1224|Proteobacteria,2VNJ2@28216|Betaproteobacteria,4ABIV@80864|Comamonadaceae	28216|Betaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
k59_142388_1	1165841.SULAR_09944	1.92e-103	316.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_34265_1	318161.Sden_2282	8.11e-49	166.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,2QBUG@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0502 family	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k59_157770_2	2340.JV46_17370	3.58e-30	114.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1J4Z2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
k59_173226_1	1244083.CSUNSWCD_1014	1.96e-27	114.0	COG2885@1|root,COG2885@2|Bacteria,1RAM5@1224|Proteobacteria,42N1T@68525|delta/epsilon subdivisions,2YMDT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_64931_1	180332.JTGN01000008_gene3940	5.09e-27	107.0	COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia	186801|Clostridia	S	beta-keto acid cleavage enzyme	kce	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
k59_111383_2	1408473.JHXO01000007_gene858	8.93e-23	96.7	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,2FNNW@200643|Bacteroidia	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_211919_1	929562.Emtol_4025	5.96e-13	73.9	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47JS6@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,PKD
k59_72594_1	1166948.JPZL01000001_gene3208	0.00021	42.7	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XHYK@135619|Oceanospirillales	135619|Oceanospirillales	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_72594_2	2340.JV46_18380	6.06e-61	191.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1J6M0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678	-	ko:K02197	-	-	-	-	ko00000	-	-	iSSON_1240.SSON_2255	CcmE
k59_72594_3	395493.BegalDRAFT_2463	1.07e-09	55.1	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
k59_72594_4	1122194.AUHU01000002_gene2856	9.35e-11	61.6	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,464ZM@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
k59_126998_1	1165841.SULAR_00340	1.56e-63	204.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_111392_2	545276.KB898729_gene1588	8.83e-15	75.9	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_188759_1	768066.HELO_2527	3.23e-10	57.8	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1XK2F@135619|Oceanospirillales	135619|Oceanospirillales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_188759_2	2340.JV46_21400	6.29e-66	213.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1J8VJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_95929_1	1214242.B446_01565	1.54e-27	116.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_127007_1	118161.KB235922_gene396	2.1e-68	217.0	COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_114127_1	1121405.dsmv_1875	9.63e-13	67.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42PRI@68525|delta/epsilon subdivisions,2X5GA@28221|Deltaproteobacteria,2MHVA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_114127_2	1499967.BAYZ01000115_gene2932	5.25e-39	144.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	2.1.2.1,2.1.2.10,2.2.1.8	ko:K00600,ko:K00605,ko:K18847	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R01221,R02300,R04125,R09099	RC00022,RC00069,RC00112,RC00183,RC01583,RC02834,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C,SHMT
k59_98744_1	565045.NOR51B_2671	3e-35	137.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria,1SQWS@1236|Gammaproteobacteria,1JBJG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k59_67903_1	106582.XP_004551417.1	0.000225	49.3	COG0666@1|root,COG5022@1|root,KOG0160@2759|Eukaryota,KOG0504@2759|Eukaryota,39NR9@33154|Opisthokonta,3CQ9R@33208|Metazoa,3E6F6@33213|Bilateria,48RXN@7711|Chordata,49NC8@7742|Vertebrata,49TBR@7898|Actinopterygii	33208|Metazoa	Z	Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family	MYO16	GO:0000902,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005886,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0007399,GO:0007417,GO:0007420,GO:0008092,GO:0008150,GO:0008285,GO:0009653,GO:0009987,GO:0010564,GO:0010948,GO:0014065,GO:0016020,GO:0016043,GO:0021549,GO:0022008,GO:0022037,GO:0023052,GO:0030030,GO:0030154,GO:0030182,GO:0030902,GO:0031175,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0035556,GO:0042127,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045786,GO:0045930,GO:0048015,GO:0048017,GO:0048468,GO:0048471,GO:0048513,GO:0048519,GO:0048523,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051015,GO:0051716,GO:0051726,GO:0060322,GO:0065007,GO:0070013,GO:0071840,GO:0071944,GO:0120036,GO:0120039,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902806,GO:1902807,GO:2000045,GO:2000134	-	ko:K17481	-	-	-	-	ko00000,ko01009,ko04812	-	-	-	Ank,Ank_2,Myosin_head,NYAP_C,NYAP_N
k59_5880_2	395493.BegalDRAFT_0559	8.32e-37	132.0	COG0457@1|root,COG0457@2|Bacteria,1R714@1224|Proteobacteria,1SA9Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_145582_1	1280001.BAOA01000128_gene1171	4.61e-84	266.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XSDF@135623|Vibrionales	135623|Vibrionales	T	containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_75624_1	283942.IL0276	3.09e-91	287.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RT11@1236|Gammaproteobacteria,2QFA7@267893|Idiomarinaceae	1236|Gammaproteobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Gmad1,PD40,Peptidase_S9,Peptidase_S9_N
k59_122105_1	1384056.N787_03270	1.07e-49	179.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1X465@135614|Xanthomonadales	135614|Xanthomonadales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_222550_1	1191523.MROS_1520	1.2e-07	54.3	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_106158_1	313596.RB2501_06960	3.17e-84	267.0	COG0517@1|root,COG3572@1|root,COG0517@2|Bacteria,COG3572@2|Bacteria,4NGW0@976|Bacteroidetes,1HYC5@117743|Flavobacteriia	976|Bacteroidetes	H	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
k59_5889_1	1165841.SULAR_04102	1.23e-115	335.0	COG2928@1|root,COG2928@2|Bacteria	2|Bacteria	S	Conserved Protein	YH67_14670	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_5889_2	1165841.SULAR_04097	2.14e-34	129.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2YMWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_222556_1	1165841.SULAR_01215	1.49e-19	86.7	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions,2YR4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_222556_2	1165841.SULAR_01220	1.5e-65	201.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,42U6Y@68525|delta/epsilon subdivisions,2YRSZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_13459_2	1123401.JHYQ01000002_gene2607	6.1e-118	369.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,461RZ@72273|Thiotrichales	72273|Thiotrichales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_29044_1	1168034.FH5T_12315	1.94e-17	81.3	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
k59_29044_2	1168034.FH5T_12310	4.65e-46	164.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,2FMC9@200643|Bacteroidia	976|Bacteroidetes	S	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_106165_1	1122951.ATUE01000005_gene1954	3.81e-12	68.9	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,3NIRG@468|Moraxellaceae	1236|Gammaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_37027_1	272942.RCAP_rcc03364	1.82e-13	71.6	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,1FB21@1060|Rhodobacter	28211|Alphaproteobacteria	H	PFAM Aminotransferase class I and II	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_37027_2	360910.BAV2451	2.06e-50	176.0	COG0132@1|root,COG4106@1|root,COG0132@2|Bacteria,COG4106@2|Bacteria,1RDRK@1224|Proteobacteria,2VXK4@28216|Betaproteobacteria,3T8X9@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	2.1.1.197,6.3.3.3	ko:K01935,ko:K02169	ko00780,ko01100,map00780,map01100	M00123,M00572,M00573,M00577	R03182,R09543	RC00003,RC00460,RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Methyltransf_25
k59_37027_3	313606.M23134_01722	5.95e-13	65.5	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_199497_1	713586.KB900536_gene91	9.09e-93	291.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
k59_245658_1	661478.OP10G_2746	4.15e-51	171.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_5895_1	234267.Acid_6570	2.78e-28	120.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_6570|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44524_1	1189620.AJXL01000065_gene3641	3.73e-22	94.4	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia,2NT1H@237|Flavobacterium	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_44524_2	1353276.JADR01000001_gene743	1.88e-44	160.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_5896_1	1408473.JHXO01000004_gene265	9.04e-35	124.0	COG0526@1|root,COG0695@1|root,COG0526@2|Bacteria,COG0695@2|Bacteria,4P326@976|Bacteroidetes,2FXYW@200643|Bacteroidia	976|Bacteroidetes	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
k59_5896_2	1408473.JHXO01000009_gene3445	6.56e-58	185.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,2FUHX@200643|Bacteroidia	976|Bacteroidetes	O	Thioredoxin	trxA2	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_5896_3	385682.AFSL01000062_gene1612	1.65e-19	81.3	COG0234@1|root,COG0234@2|Bacteria,4P42G@976|Bacteroidetes,2FYFP@200643|Bacteroidia,3XKB4@558415|Marinilabiliaceae	976|Bacteroidetes	O	Chaperonin 10 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
k59_175960_1	1178482.BJB45_12045	1.37e-80	260.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHCN@135619|Oceanospirillales	135619|Oceanospirillales	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_98769_1	1165841.SULAR_03727	5.44e-30	112.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42RW5@68525|delta/epsilon subdivisions,2YT3G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_98769_2	1165841.SULAR_03722	3.45e-62	206.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,42P5S@68525|delta/epsilon subdivisions,2YNR9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	edd	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_214711_1	313596.RB2501_06470	1.39e-65	216.0	COG3266@1|root,COG3266@2|Bacteria,4NH1U@976|Bacteroidetes,1HX0D@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_21202_1	1469245.JFBG01000008_gene768	8.07e-18	83.2	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	transport system involved in gliding motility, auxiliary component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_21202_2	754476.Q7A_817	7.88e-54	176.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,46210@72273|Thiotrichales	72273|Thiotrichales	S	CcmB protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_122146_1	745411.B3C1_08781	1.71e-28	120.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,DUF285,FIVAR,PG_binding_1,Pertactin,Phage_fiber_2,Sel1,YSIRK_signal
k59_214714_1	1333507.AUTQ01000069_gene2165	1.24e-56	196.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,1T257@1236|Gammaproteobacteria,2Q0EY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,DUF3369,HD,HD_5,Response_reg
k59_37032_1	1382306.JNIM01000001_gene2581	3.53e-61	209.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
k59_230037_1	1499680.CCFE01000011_gene703	5.54e-26	110.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,4H9P7@91061|Bacilli,1ZBC6@1386|Bacillus	91061|Bacilli	S	Membrane	ycgA	-	-	-	-	-	-	-	-	-	-	-	DcuC
k59_199823_2	1121373.KB903665_gene3132	1.39e-17	82.8	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,47JQ0@768503|Cytophagia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_60306_1	502025.Hoch_4262	9.35e-50	179.0	COG0025@1|root,COG1762@1|root,COG0025@2|Bacteria,COG1762@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
k59_21569_1	765911.Thivi_3396	1.13e-74	240.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWWZ@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
k59_99143_1	1168034.FH5T_18985	3.71e-118	360.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,2FNBG@200643|Bacteroidia	976|Bacteroidetes	M	transglycosylase	ponA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_29470_1	545276.KB898727_gene460	1.61e-17	79.3	2E1SU@1|root,32X2N@2|Bacteria,1N4HW@1224|Proteobacteria,1SAEX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160904_2	997884.HMPREF1068_00642	3.77e-14	74.7	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_191925_1	1165841.SULAR_00425	5.06e-149	434.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_6293_1	1245469.S58_09660	1.28e-24	108.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,3JQV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
k59_106586_1	331869.BAL199_08568	1.42e-102	311.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,4BQ8P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_130111_1	1049564.TevJSym_ac00110	8.75e-19	83.2	COG2863@1|root,COG2863@2|Bacteria,1R6DK@1224|Proteobacteria	1224|Proteobacteria	C	Pfam cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_130111_2	522306.CAP2UW1_3418	4.27e-32	115.0	COG2863@1|root,COG2863@2|Bacteria,1N1DQ@1224|Proteobacteria,2VTXW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
k59_130111_3	1049564.TevJSym_ac00130	4.11e-219	623.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide	nosZ	GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	COX2,Cupredoxin_1
k59_238347_1	387093.SUN_0170	2.98e-62	205.0	COG1246@1|root,COG2172@1|root,COG1246@2|Bacteria,COG2172@2|Bacteria,1QZN7@1224|Proteobacteria,43CKZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_21582_1	290318.Cvib_0073	4.25e-54	196.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria	2|Bacteria	L	dead DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,NERD,UvrD_C_2
k59_137575_1	349124.Hhal_0475	1.56e-45	157.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1WWSX@135613|Chromatiales	135613|Chromatiales	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	-	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k59_199834_1	879212.DespoDRAFT_03471	4.33e-46	169.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_29492_1	2340.JV46_07080	1.34e-109	330.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1J4ZC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_169057_1	227377.CBU_1584	1.17e-09	58.2	COG1863@1|root,COG1863@2|Bacteria,1RH9F@1224|Proteobacteria,1S66D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Multisubunit Na H antiporter MnhE subunit	phaE	-	-	ko:K05562,ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
k59_169057_2	1282876.BAOK01000001_gene1972	6.51e-24	93.6	COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria,2UHB7@28211|Alphaproteobacteria,4BQRV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
k59_91167_1	768671.ThimaDRAFT_0334	1.16e-37	135.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1WXG2@135613|Chromatiales	135613|Chromatiales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_91167_2	857087.Metme_0886	1.5e-28	111.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1XE2G@135618|Methylococcales	135618|Methylococcales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
k59_68237_1	247633.GP2143_06350	5.66e-30	115.0	COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,1RYI5@1236|Gammaproteobacteria,1J4XB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-bound metal-dependent hydrolases	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_106604_1	1151061.CAJY01000040_gene4136	6.76e-137	411.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_184267_1	768671.ThimaDRAFT_3217	1.49e-143	416.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWG6@135613|Chromatiales	135613|Chromatiales	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_83415_1	1037409.BJ6T_74500	1.58e-05	52.0	COG1835@1|root,COG1835@2|Bacteria,1N0EY@1224|Proteobacteria,2U13G@28211|Alphaproteobacteria,3JU05@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_222935_1	1247963.JPHU01000001_gene2087	1.26e-55	183.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Outer membrane protein W	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_37370_2	1049564.TevJSym_au00070	7.07e-24	99.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,1JAAK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_99171_1	269798.CHU_1581	8.11e-88	277.0	COG0438@1|root,COG0438@2|Bacteria,4PKQN@976|Bacteroidetes,47K56@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycogen synthase	-	-	2.4.1.11	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3	-	Glycogen_syn
k59_191935_1	1122197.ATWI01000008_gene2993	5.35e-20	88.6	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,466V7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0066	yaeB	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_191935_2	631362.Thi970DRAFT_01926	1.89e-35	123.0	2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,1SBDA@1236|Gammaproteobacteria,1WZ0Q@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_153119_1	1122137.AQXF01000001_gene3013	4.92e-30	114.0	COG0625@1|root,COG0625@2|Bacteria,1PENB@1224|Proteobacteria,2TRVC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	gstch9	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
k59_202535_1	519989.ECTPHS_01769	8.43e-109	328.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	ko:K04691	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
k59_202535_2	1070319.CAGGBEG34_240070	3.54e-21	89.7	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,1K03Z@119060|Burkholderiaceae	28216|Betaproteobacteria	S	NIF3 (NGG1p interacting factor 3)	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_225733_2	1281779.H009_17048	1.21e-16	75.5	2E3WG@1|root,32YTM@2|Bacteria,1N8TX@1224|Proteobacteria,2UFMP@28211|Alphaproteobacteria,4BHGS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3768)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3768
k59_40198_1	1168034.FH5T_11530	1.74e-33	127.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,2FN1M@200643|Bacteroidia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_40198_2	1168034.FH5T_11525	2.21e-21	90.5	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,2FMH1@200643|Bacteroidia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_1447_1	690850.Desaf_0981	1.3e-52	183.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2M8I0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
k59_132872_1	1095769.CAHF01000022_gene432	9.82e-82	272.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_241128_1	448385.sce1237	8.15e-12	73.2	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria	1224|Proteobacteria	G	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
k59_140723_1	1349767.GJA_161	6.47e-75	256.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,473K1@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Linear gramicidin synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_94304_1	1121405.dsmv_0344	5.37e-28	107.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,42U47@68525|delta/epsilon subdivisions,2WP68@28221|Deltaproteobacteria,2MK5D@213118|Desulfobacterales	28221|Deltaproteobacteria	H	5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_32609_1	387093.SUN_0193	1.37e-122	371.0	COG4166@1|root,COG4166@2|Bacteria,1Q4KZ@1224|Proteobacteria,43A0X@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_233630_1	1165841.SULAR_06988	6.04e-30	115.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_233630_2	1165841.SULAR_06993	5.74e-46	157.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_202542_1	329726.AM1_4531	1.34e-06	59.3	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	aprA	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009405,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0031638,GO:0043170,GO:0044238,GO:0044419,GO:0051604,GO:0051704,GO:0071704,GO:0140096,GO:1901564	3.4.24.40	ko:K01406,ko:K20276	ko01503,ko02024,map01503,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HemolysinCabind,Peptidase_M10,Peptidase_M10_C,Reprolysin_4
k59_132885_1	713587.THITH_09725	1.91e-43	148.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_117468_1	1049564.TevJSym_ak00260	5.35e-81	255.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
k59_163864_1	1165841.SULAR_01345	3.3e-121	372.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_163864_2	1537917.JU82_07820	4.14e-16	77.8	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42R15@68525|delta/epsilon subdivisions,2YNVA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_101967_1	102125.Xen7305DRAFT_00014310	1.82e-20	98.6	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1G2S0@1117|Cyanobacteria	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4
k59_16762_1	1150626.PHAMO_20071	1.43e-14	79.0	COG3321@1|root,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,2UR2U@28211|Alphaproteobacteria,2JYVD@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG3321 Polyketide synthase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_70957_1	530564.Psta_3232	2.23e-79	254.0	COG0265@1|root,COG1506@1|root,COG3975@1|root,COG0265@2|Bacteria,COG1506@2|Bacteria,COG3975@2|Bacteria,2IY6F@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_179426_2	1168034.FH5T_07500	1.25e-34	123.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,2FXAB@200643|Bacteroidia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_210171_1	153948.NAL212_2800	7.3e-37	135.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,371ZS@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_194786_1	387093.SUN_0676	1.27e-67	209.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2YMVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_194786_2	1165841.SULAR_04092	1.36e-28	106.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2YNZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_148328_1	1165841.SULAR_09339	1.04e-82	249.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_1476_1	234267.Acid_2266	2.09e-56	196.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
k59_86550_1	1041159.AZUW01000017_gene2190	4.47e-38	135.0	2E3VP@1|root,32YSV@2|Bacteria,1RFZF@1224|Proteobacteria,2UFT8@28211|Alphaproteobacteria,4BK77@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_234039_2	688270.Celal_1794	2.59e-68	214.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1HYV8@117743|Flavobacteriia,1FA4H@104264|Cellulophaga	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_164209_1	316067.Geob_3417	5.34e-34	130.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,43SHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
k59_234040_1	313596.RB2501_06465	2.11e-85	255.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_234040_2	1348583.ATLH01000029_gene1793	5.37e-22	89.0	2E32X@1|root,32Y35@2|Bacteria,4NUUU@976|Bacteroidetes,1I54Q@117743|Flavobacteriia,1F9HH@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_71298_1	517418.Ctha_1398	2.24e-36	132.0	COG0543@1|root,COG0543@2|Bacteria,1FDJ4@1090|Chlorobi	1090|Chlorobi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
k59_71298_2	428125.CLOLEP_02352	2.76e-11	63.9	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGEA@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_234044_1	1165841.SULAR_07620	2.13e-33	117.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42SCR@68525|delta/epsilon subdivisions,2YP9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_24979_1	246196.MSMEI_6410	1.39e-47	176.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,234WD@1762|Mycobacteriaceae	201174|Actinobacteria	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_164213_1	2340.JV46_16920	2.14e-85	262.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_94742_1	227086.JGI_V11_88440	1.61e-11	69.7	COG2234@1|root,2R701@2759|Eukaryota	2759|Eukaryota	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_94742_2	1131269.AQVV01000031_gene287	5.55e-40	148.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
k59_102272_1	391615.ABSJ01000022_gene284	9.72e-53	186.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08483,ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_40573_1	1041826.FCOL_01345	4.76e-18	82.0	COG3415@1|root,COG3415@2|Bacteria,4NZ4U@976|Bacteroidetes,1I6F6@117743|Flavobacteriia	976|Bacteroidetes	L	COG3415 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_33
k59_102273_2	2340.JV46_20270	6.35e-67	204.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,1J799@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_102273_3	1538295.JY96_04105	2.82e-06	47.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,1KK8V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_94744_3	314265.R2601_05638	9.4e-37	133.0	2E3TX@1|root,32YRB@2|Bacteria,1RAN2@1224|Proteobacteria,2TXXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86882_1	1353276.JADR01000003_gene2893	4.05e-26	103.0	29WC5@1|root,30HXS@2|Bacteria,4NNWN@976|Bacteroidetes,1I218@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86882_2	1223410.KN050846_gene2491	1.17e-08	55.1	29WC5@1|root,30HXS@2|Bacteria,4NNWN@976|Bacteroidetes,1I218@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_226097_1	1165841.SULAR_05938	4.98e-49	158.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2YPC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k59_226097_2	1165841.SULAR_05933	5.99e-61	198.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2YMUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_156433_1	42565.FP66_00700	2.21e-37	129.0	COG3126@1|root,COG3126@2|Bacteria,1N8AF@1224|Proteobacteria,1SCM7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ybaY	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	YscW
k59_172007_1	550540.Fbal_2700	2.84e-38	147.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345	SBP_bac_3,SLT
k59_48278_1	537013.CLOSTMETH_03829	1.81e-42	159.0	COG1409@1|root,COG3408@1|root,COG1409@2|Bacteria,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,3WHJG@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-rhamnosidase N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,FIVAR
k59_94755_1	491952.Mar181_1162	4.14e-46	154.0	COG1733@1|root,COG1733@2|Bacteria,1RF0R@1224|Proteobacteria,1S6ND@1236|Gammaproteobacteria,1XK2Z@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k59_79268_1	1499967.BAYZ01000083_gene1027	2.12e-05	48.1	COG0840@1|root,COG4251@1|root,COG0840@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,MCPsignal
k59_48283_1	391587.KAOT1_20012	8.95e-54	172.0	COG2963@1|root,COG2963@2|Bacteria,4NQGJ@976|Bacteroidetes,1I2UE@117743|Flavobacteriia	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28
k59_86892_1	1232437.KL662019_gene628	5.39e-47	160.0	COG3385@1|root,COG3385@2|Bacteria,1NUI6@1224|Proteobacteria,42ZJ8@68525|delta/epsilon subdivisions,2WV27@28221|Deltaproteobacteria,2MND0@213118|Desulfobacterales	28221|Deltaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55948_1	2340.JV46_22230	5.36e-18	77.8	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1SBVN@1236|Gammaproteobacteria,1JBWS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Bacterial DNA-binding protein	hup	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
k59_55948_2	2340.JV46_15320	1.41e-112	334.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	pyridine nucleotide-disulphide oxidoreductase	sqr	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_71321_1	1121875.KB907548_gene1662	1.04e-74	231.0	2E3AK@1|root,320TI@2|Bacteria,4NRX2@976|Bacteroidetes,1I44M@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156442_1	1215915.BN193_10770	3.2e-25	102.0	COG3039@1|root,COG3039@2|Bacteria,1VJ28@1239|Firmicutes,4HQR7@91061|Bacilli	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_164238_1	880073.Calab_0585	2.49e-20	87.4	COG1487@1|root,COG1487@2|Bacteria,2NS13@2323|unclassified Bacteria	2|Bacteria	S	PIN domain	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_164238_2	46234.ANA_C13518	5.76e-07	48.1	COG3609@1|root,COG3609@2|Bacteria,1GHTT@1117|Cyanobacteria,1HPYA@1161|Nostocales	1117|Cyanobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1878_1	981085.XP_010086549.1	3.41e-52	167.0	COG1007@1|root,KOG4668@2759|Eukaryota,37WWH@33090|Viridiplantae,3GKTY@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_17199_1	1123248.KB893323_gene1573	4.81e-24	99.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1IPD8@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_205796_1	1121904.ARBP01000002_gene7236	2.79e-24	104.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_27840_1	103690.17135445	1.44e-09	67.8	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase
k59_221369_1	1121875.KB907550_gene639	3.23e-99	325.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
k59_213561_1	335659.S23_09560	1.39e-09	58.2	COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2UF5S@28211|Alphaproteobacteria,3JW0R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	MA20_18635	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_213561_2	717774.Marme_2942	2.69e-41	154.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_58700_1	340177.Cag_0368	1.66e-52	176.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
k59_120826_1	545276.KB898725_gene855	2.22e-69	221.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1WX9E@135613|Chromatiales	135613|Chromatiales	E	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_27844_1	1231185.BAMP01000037_gene646	5.04e-49	169.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TQVT@28211|Alphaproteobacteria,43JB5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	dctP_1	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_50957_1	1049564.TevJSym_aj00730	2.04e-23	105.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1J4N6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_9,Response_reg
k59_159333_1	1121921.KB898710_gene658	3.11e-12	78.6	COG2373@1|root,COG2931@1|root,COG4254@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,He_PIG,OmpA,OmpA_membrane,fn3
k59_190340_1	1384056.N787_07260	4.3e-53	180.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1X3Q9@135614|Xanthomonadales	135614|Xanthomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_213579_1	1049564.TevJSym_al00160	3.59e-55	191.0	COG3291@1|root,COG3291@2|Bacteria,1R5MQ@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c5530 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_151492_1	1165841.SULAR_06043	4.25e-100	308.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_198308_1	395493.BegalDRAFT_0733	2.82e-159	496.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
k59_58720_1	697282.Mettu_3926	1.66e-35	144.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,1T3G2@1236|Gammaproteobacteria,1XH16@135618|Methylococcales	135618|Methylococcales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_174714_1	444859.E3SI15_9CAUD	4.13e-58	195.0	4QAJD@10239|Viruses,4QW4M@35237|dsDNA viruses  no RNA stage,4QQ7U@28883|Caudovirales,4QIAP@10662|Myoviridae	10662|Myoviridae	S	gp32 DNA binding protein like	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_244445_1	335543.Sfum_2600	1.63e-106	322.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_136163_1	985665.HPL003_02340	1.22e-29	117.0	28JEU@1|root,2Z98W@2|Bacteria,1VRU4@1239|Firmicutes,4HTWS@91061|Bacilli,26VIY@186822|Paenibacillaceae	91061|Bacilli	S	PFAM MULE transposase, conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_228892_1	758.BBIX01000006_gene772	1.98e-12	71.2	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1Y9T1@135625|Pasteurellales	135625|Pasteurellales	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,ResIII
k59_144103_1	313596.RB2501_13124	5.31e-96	289.0	COG2159@1|root,COG2159@2|Bacteria,4NK6T@976|Bacteroidetes,1I2BN@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
k59_82012_1	439235.Dalk_3488	1.67e-68	222.0	COG0500@1|root,COG1047@1|root,COG1047@2|Bacteria,COG2226@2|Bacteria,1PCH2@1224|Proteobacteria,42M58@68525|delta/epsilon subdivisions,2WK5Z@28221|Deltaproteobacteria,2MIYH@213118|Desulfobacterales	28221|Deltaproteobacteria	OQ	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_182890_1	765914.ThisiDRAFT_1665	8.92e-103	301.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_213819_1	857087.Metme_2828	5.39e-40	137.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1XF4C@135618|Methylococcales	135618|Methylococcales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k59_213819_2	2340.JV46_20780	9.43e-51	167.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
k59_82213_1	765912.Thimo_2944	4.59e-09	57.4	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales	135613|Chromatiales	K	LysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_82213_2	765910.MARPU_00180	4.38e-45	149.0	COG1320@1|root,COG1320@2|Bacteria,1MZ6Z@1224|Proteobacteria,1S8TM@1236|Gammaproteobacteria,1WYJD@135613|Chromatiales	135613|Chromatiales	P	PFAM Na H antiporter subunit	-	-	-	ko:K05564	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	PhaG_MnhG_YufB
k59_82213_3	765913.ThidrDRAFT_3433	7.63e-27	100.0	COG2212@1|root,COG2212@2|Bacteria,1N8WJ@1224|Proteobacteria,1S8ZM@1236|Gammaproteobacteria,1WZ3A@135613|Chromatiales	135613|Chromatiales	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05563	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MrpF_PhaF
k59_66883_1	1094715.CM001373_gene748	7.05e-11	62.4	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1JDNX@118969|Legionellales	118969|Legionellales	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_66883_2	864073.HFRIS_010119	4.55e-17	82.0	COG0745@1|root,COG4977@1|root,COG0745@2|Bacteria,COG4977@2|Bacteria,1R3WE@1224|Proteobacteria,2WI4D@28216|Betaproteobacteria,478WY@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
k59_190659_1	313606.M23134_02856	1.52e-35	139.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_105272_1	768671.ThimaDRAFT_3563	1.09e-45	163.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXY0@135613|Chromatiales	135613|Chromatiales	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
k59_105272_2	1123401.JHYQ01000008_gene418	1.39e-45	158.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,45ZS4@72273|Thiotrichales	72273|Thiotrichales	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_74561_1	387093.SUN_2377	2.69e-71	223.0	COG3900@1|root,COG3900@2|Bacteria,1NDBM@1224|Proteobacteria,43APD@68525|delta/epsilon subdivisions	2|Bacteria	S	Predicted periplasmic protein (DUF2092)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092
k59_82215_1	1123368.AUIS01000007_gene2681	1.24e-104	327.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,2NCDM@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_113184_1	72664.XP_006405523.1	5.88e-256	701.0	28IP8@1|root,2QR09@2759|Eukaryota,37PUB@33090|Viridiplantae,3GEYD@35493|Streptophyta,3HX10@3699|Brassicales	35493|Streptophyta	C	Photosystem II (PSII) is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1 D2 (PsbA PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors	psbA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0010287,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	1.10.3.9	ko:K02703,ko:K20000	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko03016	-	-	-	Photo_RC
k59_113184_2	4577.GRMZM5G836994_P01	3.7e-16	79.0	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,3KWRZ@4447|Liliopsida,3IFBD@38820|Poales	35493|Streptophyta	J	Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_82222_1	1122176.KB903535_gene1981	4.36e-05	46.2	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1IWT1@117747|Sphingobacteriia	976|Bacteroidetes	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_82222_2	1168034.FH5T_05050	4.98e-64	207.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,2FM6X@200643|Bacteroidia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_198519_1	1165841.SULAR_01320	1.57e-49	164.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42R15@68525|delta/epsilon subdivisions,2YNVA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_198519_2	1249627.D779_4114	5.41e-44	165.0	2DKXC@1|root,30RJ8@2|Bacteria,1R3H2@1224|Proteobacteria,1T67X@1236|Gammaproteobacteria,1X2X3@135613|Chromatiales	135613|Chromatiales	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
k59_105288_1	1168034.FH5T_13830	4.73e-112	346.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
k59_66906_1	391615.ABSJ01000016_gene1742	3.89e-40	147.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1J50B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_66906_2	572477.Alvin_1223	3.29e-19	85.5	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1WWI0@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_144491_2	1047013.AQSP01000133_gene2159	3.1e-17	79.0	COG1664@1|root,COG1664@2|Bacteria,2NQ1N@2323|unclassified Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
k59_144491_3	1274402.JQAJ01000003_gene668	4.11e-16	78.2	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria,47ET2@766|Rickettsiales	766|Rickettsiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_159586_2	1215092.PA6_024_00050	2.85e-32	114.0	COG3905@1|root,COG3905@2|Bacteria,1N8CE@1224|Proteobacteria,1SAXF@1236|Gammaproteobacteria,1YH2I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
k59_43573_2	2340.JV46_22570	1.33e-42	156.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,1RR35@1236|Gammaproteobacteria,1J87X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k59_221546_1	118161.KB235922_gene4457	1.78e-50	177.0	COG0145@1|root,COG0145@2|Bacteria,1G02W@1117|Cyanobacteria,3VJCP@52604|Pleurocapsales	1117|Cyanobacteria	EQ	Hydantoinase oxoprolinase N-terminal region	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_82230_1	4081.Solyc01g007640.2.1	0.0	959.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_237168_1	313596.RB2501_14289	4.7e-115	352.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_198541_1	349741.Amuc_1655	4.04e-41	152.0	COG3119@1|root,COG3119@2|Bacteria,46SHT@74201|Verrucomicrobia,2IUAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_167647_2	1168034.FH5T_08900	1.21e-117	343.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,2FP5N@200643|Bacteroidia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_136338_1	1207076.ALAT01000185_gene2641	1.05e-17	81.3	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,1Z1A6@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	V	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	fusE	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_136338_2	398767.Glov_1440	1.07e-74	231.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,42PWU@68525|delta/epsilon subdivisions,2X5GP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_221552_1	1121878.AUGL01000010_gene964	3.84e-33	130.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1SKSP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
k59_182925_1	225937.HP15_3587	1.45e-14	74.7	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,4643R@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1705)	-	-	2.7.8.43	ko:K03760,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_182925_2	1144325.PMI22_00554	6.29e-12	71.2	COG3907@1|root,COG3907@2|Bacteria,1MU4M@1224|Proteobacteria,1S4HB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PAP2 (Acid phosphatase) superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_5060_1	1121396.KB892913_gene116	2.96e-106	326.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_167652_1	2340.JV46_11900	3.66e-26	103.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1J5J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,NAD_binding_1
k59_167652_2	1049564.TevJSym_at00190	7.36e-50	162.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1J5X0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_58958_2	96561.Dole_0218	8.47e-20	83.2	2AVIJ@1|root,31MB4@2|Bacteria,1RI2Y@1224|Proteobacteria,430QG@68525|delta/epsilon subdivisions,2WW6C@28221|Deltaproteobacteria,2MNR1@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43588_1	472759.Nhal_3178	1.45e-101	307.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_66933_1	1168034.FH5T_18275	5.95e-150	430.0	COG0111@1|root,COG0111@2|Bacteria,4NGEB@976|Bacteroidetes,2FMMV@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k59_5063_1	497964.CfE428DRAFT_2264	1.5e-90	280.0	COG3119@1|root,COG3119@2|Bacteria,46UNC@74201|Verrucomicrobia	2|Bacteria	P	Domain of unknown function (DUF4976)	mdsA	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
k59_144527_1	1168034.FH5T_13525	2.6e-70	236.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,2FPNU@200643|Bacteroidia	976|Bacteroidetes	L	SNF2 family N-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N
k59_128847_1	2340.JV46_06070	9.78e-84	265.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1J5MS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	atmA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_36100_1	886377.Murru_2961	9.26e-89	276.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HX7D@117743|Flavobacteriia	976|Bacteroidetes	V	Multidrug transporter MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_105321_1	313596.RB2501_09580	5.96e-42	143.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1IJPJ@117743|Flavobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_105321_2	411154.GFO_0018	5.73e-35	134.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
k59_162831_1	1177181.T9A_00948	6.53e-67	216.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1XIMC@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_39070_1	1035839.AFNK01000071_gene667	6.72e-12	65.1	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,1Y71X@135625|Pasteurellales	135625|Pasteurellales	S	UPF0142 protein	Z012_04650	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_424_1	646529.Desaci_2936	8.13e-60	205.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia,260K6@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
k59_77746_1	2340.JV46_11710	9.31e-101	295.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1J4K8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050	Sod_Fe_C,Sod_Fe_N
k59_116460_1	2340.JV46_03460	2.77e-76	257.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_170651_1	420324.KI911996_gene7918	7.39e-14	72.4	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,1JUVQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_70005_1	1165841.SULAR_04532	4.14e-129	395.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_8186_1	2340.JV46_05330	7.04e-40	135.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,1S6Y2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
k59_8186_2	2340.JV46_05320	6.13e-74	237.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,1S0H0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_124085_1	1165841.SULAR_02433	1.02e-92	279.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_232537_1	1168034.FH5T_10215	7.52e-83	259.0	COG3203@1|root,COG3203@2|Bacteria,4NMHJ@976|Bacteroidetes,2FT17@200643|Bacteroidia	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_155177_1	1215092.PA6_009_00220	1.45e-54	194.0	291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62309_2	85681.XP_006427723.1	1.08e-62	209.0	COG2303@1|root,KOG1238@2759|Eukaryota,37ING@33090|Viridiplantae,3GE1F@35493|Streptophyta	35493|Streptophyta	E	(R)-mandelonitrile lyase-like	-	-	4.1.2.10	ko:K08248	ko00460,ko01110,map00460,map01110	-	R01409,R01767,R02811	RC00597,RC00598,RC00784,RC02852	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_8198_1	313596.RB2501_03695	7.69e-117	347.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
k59_209307_1	1403819.BATR01000118_gene4176	7.26e-21	92.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_240229_1	640081.Dsui_1647	9.76e-70	225.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,2KVK4@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_217099_2	883126.HMPREF9710_01848	6.26e-27	111.0	COG0303@1|root,COG0746@1|root,COG0303@2|Bacteria,COG0746@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,473QZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_31504_1	946362.XP_004991702.1	2.69e-22	102.0	COG3321@1|root,KOG1202@2759|Eukaryota,38D6P@33154|Opisthokonta	33154|Opisthokonta	I	phosphopantetheine binding	FASN	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_108748_1	264462.Bd1346	4.54e-47	158.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,42W1X@68525|delta/epsilon subdivisions,2MTXK@213481|Bdellovibrionales,2WRUK@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
k59_93343_1	57918.XP_004301673.1	3.86e-19	89.7	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta,4JN0G@91835|fabids	35493|Streptophyta	L	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3,Retrotrans_gag,rve
k59_116469_1	1089547.KB913013_gene2262	3.31e-33	133.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_93351_1	1165841.SULAR_00455	5.66e-65	212.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OprD,Porin_4
k59_170677_1	998088.B565_3713	9.82e-110	327.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_224765_2	1550091.JROE01000001_gene3986	2.29e-22	96.3	COG3622@1|root,COG3622@2|Bacteria,4PM6P@976|Bacteroidetes,1J0S4@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_31517_1	268739.Nmlp_1968	1.53e-13	76.6	COG3979@1|root,arCOG07560@1|root,arCOG07560@2157|Archaea,arCOG07581@2157|Archaea,2Y0PT@28890|Euryarchaeota	28890|Euryarchaeota	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_178443_1	1168034.FH5T_09990	7.37e-54	179.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,2FNEC@200643|Bacteroidia	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_85537_1	1165841.SULAR_10549	7.59e-41	144.0	COG0475@1|root,COG0475@2|Bacteria,1RFKE@1224|Proteobacteria,43B2P@68525|delta/epsilon subdivisions,2YT5F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_85537_2	1165841.SULAR_10544	3.02e-52	172.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2YMH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_77783_1	1165841.SULAR_01663	2.44e-146	421.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,42MVB@68525|delta/epsilon subdivisions,2YNU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	O-acetylhomoserine sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_201596_1	1165841.SULAR_01395	1.15e-104	310.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2YMPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_201596_2	1165841.SULAR_01390	1.72e-39	134.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_46838_3	1499967.BAYZ01000023_gene259	2.46e-26	99.8	2DR9H@1|root,33ASP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31529_2	1195246.AGRI_07190	3.49e-52	174.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_217122_1	179408.Osc7112_5096	7.51e-57	199.0	COG0515@1|root,COG0745@1|root,COG2203@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
k59_170690_1	387093.SUN_0361	2.7e-57	185.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
k59_170694_1	1122243.KB903775_gene2011	2.02e-11	65.5	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,3NIH9@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
k59_170694_2	1385517.N800_15240	3.62e-17	81.6	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1X3US@135614|Xanthomonadales	135614|Xanthomonadales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_201610_1	1049564.TevJSym_ao00410	5.57e-18	76.6	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,1SI73@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201610_2	1196095.GAPWK_2109	0.000286	44.3	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	uup	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_62330_1	935863.AWZR01000007_gene204	7.48e-110	340.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales	135614|Xanthomonadales	I	converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k59_124124_1	439235.Dalk_4082	3.6e-27	109.0	COG1102@1|root,COG1102@2|Bacteria,1R9XZ@1224|Proteobacteria,42R78@68525|delta/epsilon subdivisions,2WN7X@28221|Deltaproteobacteria,2MJR4@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_78082_2	1049564.TevJSym_ag00450	1.11e-156	452.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1J5AP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0417	Anth_synt_I_N,Chorismate_bind
k59_8483_1	1396858.Q666_07930	0.000692	41.6	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,1SGEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM VanZ	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k59_8483_2	864702.OsccyDRAFT_2612	2.94e-90	270.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1H72I@1150|Oscillatoriales	1117|Cyanobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_147701_2	1445613.JALM01000023_gene4324	5.96e-30	119.0	COG1574@1|root,COG1574@2|Bacteria,2IBQ5@201174|Actinobacteria,4E8E4@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_109013_1	933262.AXAM01000015_gene78	7.52e-34	129.0	COG1451@1|root,COG1451@2|Bacteria,1RDZ9@1224|Proteobacteria,42SB4@68525|delta/epsilon subdivisions,2WNVN@28221|Deltaproteobacteria,2MKE7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2786,SprT-like
k59_116859_1	930166.CD58_11795	8.14e-108	335.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria	1224|Proteobacteria	T	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL,Polyketide_cyc2
k59_70324_1	1168034.FH5T_15545	6.67e-136	405.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,2FMEB@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_194093_1	395493.BegalDRAFT_1285	3.68e-46	171.0	COG1672@1|root,COG1672@2|Bacteria,1N54W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78085_2	572477.Alvin_3277	2.23e-14	76.6	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1WWHX@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C
k59_155500_2	395493.BegalDRAFT_0303	1.15e-15	72.8	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_34
k59_39447_1	314278.NB231_09418	8.82e-91	285.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1WWU6@135613|Chromatiales	135613|Chromatiales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_85878_1	913325.N799_11685	7.35e-31	125.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1X4NZ@135614|Xanthomonadales	135614|Xanthomonadales	C	Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0)	-	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	HMA,Pyr_redox_2,Pyr_redox_dim
k59_171004_1	2340.JV46_22290	1.31e-42	148.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1J4DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Mg2 and Co2 transporter CorC	corC	GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_171004_2	42565.FP66_12600	1.19e-37	131.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XJZW@135619|Oceanospirillales	135619|Oceanospirillales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_150429_2	1156844.KB891798_gene6349	1.62e-25	107.0	COG3173@1|root,COG3173@2|Bacteria,2HH8W@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
k59_57630_1	637389.Acaty_c1775	8.78e-13	65.5	COG1734@1|root,COG1734@2|Bacteria,1PUIF@1224|Proteobacteria,1T8U8@1236|Gammaproteobacteria,2NDF8@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_57630_4	1121286.AUMT01000013_gene2677	1.18e-30	131.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	res	-	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
k59_3777_2	2340.JV46_16390	3.69e-28	104.0	2ESVH@1|root,33KDW@2|Bacteria,1NI9I@1224|Proteobacteria,1SJ2N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34709_1	1042376.AFPK01000067_gene826	2.35e-64	214.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1I0PW@117743|Flavobacteriia	976|Bacteroidetes	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_135099_1	1232410.KI421421_gene3446	4.8e-34	129.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,42TEX@68525|delta/epsilon subdivisions,2WPG8@28221|Deltaproteobacteria,43T5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_181663_1	1443665.JACA01000001_gene3025	6.85e-17	92.4	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1IKPF@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
k59_112038_1	1487953.JMKF01000095_gene5128	4.69e-11	62.8	COG1433@1|root,COG1433@2|Bacteria,1GAM6@1117|Cyanobacteria,1HECB@1150|Oscillatoriales	1117|Cyanobacteria	S	Dinitrogenase iron-molybdenum cofactor, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
k59_135100_1	1165841.SULAR_01693	5.71e-59	185.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2YPJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_135100_2	1165841.SULAR_01698	4.03e-28	110.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_81047_1	497964.CfE428DRAFT_3608	1.91e-05	45.8	COG0394@1|root,COG0698@1|root,COG0394@2|Bacteria,COG0698@2|Bacteria,46W2V@74201|Verrucomicrobia	74201|Verrucomicrobia	T	low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_81047_2	2340.JV46_26130	5.79e-214	597.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1SJJV@1236|Gammaproteobacteria,1J77S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	-	-	-	-	-	-	-	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
k59_181671_1	1168034.FH5T_22110	2.74e-100	306.0	COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_158294_1	237368.SCABRO_03007	2.01e-108	332.0	2A1MP@1|root,30PVX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_204707_1	4929.XP_001486234.1	0.00026	48.5	COG0553@1|root,KOG0385@2759|Eukaryota,38CTE@33154|Opisthokonta,3NX78@4751|Fungi,3QKZ4@4890|Ascomycota,3RR0C@4891|Saccharomycetes,47A8V@766764|Debaryomycetaceae	4751|Fungi	A	SNF2 family N-terminal domain	IRC5	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K19001	-	-	-	-	ko00000,ko03036	-	-	-	Helicase_C,SNF2_N
k59_212510_2	948565.AFFP02000031_gene1562	6.58e-33	120.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1Y8M4@135625|Pasteurellales	135625|Pasteurellales	D	Nucleotide-binding protein implicated in inhibition of septum formation	Z012_09390	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_220347_1	1353529.M899_0426	1.28e-50	182.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2MU1Z@213481|Bdellovibrionales,2WJRI@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	PFAM MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_158296_2	1165841.SULAR_08237	7.92e-35	120.0	COG1918@1|root,COG1918@2|Bacteria,1Q53C@1224|Proteobacteria,42X0A@68525|delta/epsilon subdivisions,2YQP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_49915_1	266265.Bxe_A3891	1.23e-97	303.0	COG0436@1|root,COG0436@2|Bacteria,1QE0D@1224|Proteobacteria,2VIUB@28216|Betaproteobacteria,1K0XZ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	asdA	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_127531_2	2340.JV46_15930	1.52e-52	169.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1SFHK@1236|Gammaproteobacteria,1JB86@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	MraZ protein, putative antitoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	MraZ
k59_135111_1	1165841.SULAR_01678	9.05e-133	386.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_166239_1	1278073.MYSTI_04341	1.27e-35	139.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria	1224|Proteobacteria	IQ	COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
k59_227853_1	94624.Bpet1403	6.72e-61	190.0	COG3293@1|root,COG3293@2|Bacteria,1N0VW@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
k59_227853_2	228410.NE2024	2.02e-63	196.0	COG3293@1|root,COG3293@2|Bacteria,1N8GF@1224|Proteobacteria,2WBR1@28216|Betaproteobacteria,373MQ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	InterPro IPR002559	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
k59_220352_1	1165841.SULAR_00490	4.27e-89	278.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_11381_1	498211.CJA_2517	4.05e-10	67.0	COG3343@1|root,COG3343@2|Bacteria,1QX02@1224|Proteobacteria	1224|Proteobacteria	K	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119770_1	767817.Desgi_1365	2.04e-94	305.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,2608I@186807|Peptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_26792_1	1121920.AUAU01000014_gene2799	9.21e-43	165.0	COG0308@1|root,COG0308@2|Bacteria,3Y71N@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_220356_1	1174528.JH992898_gene1303	2.01e-56	188.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G3DB@1117|Cyanobacteria	1117|Cyanobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
k59_26797_3	1391428.V5KSH7_9CAUD	1.16e-10	63.2	4QCWQ@10239|Viruses,4QZPT@35237|dsDNA viruses  no RNA stage,4QQZU@28883|Caudovirales,4QHV0@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_204724_1	1134474.O59_000014	2.01e-128	379.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,1FFVN@10|Cellvibrio	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
k59_73165_1	29730.Gorai.001G163400.1	7.32e-142	418.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,3GBUN@35493|Streptophyta	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k59_143013_1	2340.JV46_12710	1.61e-158	476.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1J4Y8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_181685_1	745411.B3C1_02820	3.01e-17	82.8	COG3295@1|root,COG3295@2|Bacteria,1R9YV@1224|Proteobacteria,1S334@1236|Gammaproteobacteria,1J6WK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative PepSY_TM-like	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM_like_2
k59_181685_2	203122.Sde_3028	6.77e-26	101.0	COG3656@1|root,COG3656@2|Bacteria,1RD03@1224|Proteobacteria,1S4R7@1236|Gammaproteobacteria,4677R@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Periplasmic protein	DR1793	-	-	-	-	-	-	-	-	-	-	-	DUF2271
k59_236239_2	1121342.AUCO01000004_gene575	4.37e-35	131.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,36ECS@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_220771_1	398527.Bphyt_4960	9.78e-54	190.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1JZMH@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	1.3.99.16	ko:K00256,ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_4272_1	796620.VIBC2010_19020	3e-82	272.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XSWZ@135623|Vibrionales	135623|Vibrionales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_104474_1	1165841.SULAR_06663	1.57e-108	327.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_89067_1	1165841.SULAR_08724	8.06e-23	95.5	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_89067_2	1172190.M947_03965	9.38e-37	134.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42YXJ@68525|delta/epsilon subdivisions,2YR3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
k59_89069_1	1168034.FH5T_19480	2.77e-105	324.0	COG3137@1|root,COG3137@2|Bacteria,4NRXD@976|Bacteroidetes,2FNZ5@200643|Bacteroidia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_166711_1	1165841.SULAR_07575	2.77e-106	310.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,43B19@68525|delta/epsilon subdivisions,2YT52@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_112462_1	1120999.JONM01000002_gene767	2.69e-23	103.0	COG0277@1|root,COG4798@1|root,COG0277@2|Bacteria,COG4798@2|Bacteria,1MV1Q@1224|Proteobacteria,2VI37@28216|Betaproteobacteria,2KS9Z@206351|Neisseriales	206351|Neisseriales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
k59_81519_1	765913.ThidrDRAFT_3135	2.23e-22	94.7	28JN1@1|root,2Z9EG@2|Bacteria,1R8TZ@1224|Proteobacteria,1S1S0@1236|Gammaproteobacteria,1WXT2@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_81519_2	2340.JV46_08450	6.1e-64	201.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1JAU3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	probably involved in intracellular septation	ispZ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k59_81519_3	1132855.KB913035_gene2135	7.22e-30	108.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,2KN2X@206350|Nitrosomonadales	206350|Nitrosomonadales	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
k59_228316_1	1165841.SULAR_07500	3.22e-95	293.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_166717_1	1121011.AUCB01000037_gene750	2.34e-08	56.2	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,1I1C4@117743|Flavobacteriia,23GJI@178469|Arenibacter	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_228317_1	313596.RB2501_05505	5.87e-112	334.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_182167_1	1165841.SULAR_06823	1.91e-50	164.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42MTC@68525|delta/epsilon subdivisions,2YMSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cosR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_205204_1	1249627.D779_2836	2.06e-17	81.3	COG0204@1|root,COG0204@2|Bacteria,1MYXG@1224|Proteobacteria,1SNGT@1236|Gammaproteobacteria,1X0M3@135613|Chromatiales	135613|Chromatiales	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_212926_1	1168034.FH5T_19085	1.17e-66	216.0	COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0E9@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
k59_150909_1	309807.SRU_1928	4.65e-42	158.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
k59_197681_1	3880.AES69832	4.92e-87	273.0	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,4JV38@91835|fabids	35493|Streptophyta	J	Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_220785_1	225117.XP_009360094.1	2.07e-20	92.8	28M03@1|root,2QTGX@2759|Eukaryota,37SBF@33090|Viridiplantae,3G88S@35493|Streptophyta,4JIS2@91835|fabids	35493|Streptophyta	S	Carbohydrate esterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
k59_143493_1	1165841.SULAR_09204	4.85e-113	337.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_65930_1	97138.C820_01542	3.55e-70	229.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,36EZX@31979|Clostridiaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_96879_2	483219.LILAB_20150	1.26e-18	85.1	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,439F3@68525|delta/epsilon subdivisions,2X4QF@28221|Deltaproteobacteria,2YZE7@29|Myxococcales	28221|Deltaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_182178_1	1123499.KB908038_gene1799	6.28e-53	170.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,2KQFH@206351|Neisseriales	206351|Neisseriales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_182178_2	751994.AGIG01000002_gene907	1.48e-23	92.8	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1J664@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_166736_1	1121405.dsmv_2946	5.66e-83	263.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2MIT4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Elongation factor Tu domain 2	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_192580_1	1049564.TevJSym_aa02160	1.03e-14	75.5	2BXIA@1|root,2ZJ26@2|Bacteria,1P6T0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192580_2	2340.JV46_20140	1.33e-40	142.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,1JA1Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
k59_91730_2	1165841.SULAR_06243	1.33e-178	503.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_14325_1	339670.Bamb_5834	4.95e-15	80.1	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_4,zinc_ribbon_2
k59_200460_1	880073.Calab_1943	1.15e-16	84.3	COG2177@1|root,COG2177@2|Bacteria,2NPIM@2323|unclassified Bacteria	2|Bacteria	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k59_123109_1	187272.Mlg_1890	1.74e-89	285.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1WXGJ@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_200462_2	938289.CAJN020000003_gene972	7.19e-06	48.5	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia,268R1@186813|unclassified Clostridiales	186801|Clostridia	K	CarD-like/TRCF domain	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
k59_60968_1	1336249.JADW01000002_gene4431	2.91e-12	69.7	COG2885@1|root,COG2885@2|Bacteria,1PG81@1224|Proteobacteria,2V8N8@28211|Alphaproteobacteria,4BK3S@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_146654_1	1121405.dsmv_2856	4.95e-68	222.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200463_1	313603.FB2170_09651	8.03e-71	215.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia,2PHQD@252356|Maribacter	976|Bacteroidetes	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k59_184851_2	1165841.SULAR_05758	2.03e-58	190.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_184852_1	929703.KE386491_gene2200	0.000852	45.4	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,47JHA@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_60975_1	1168034.FH5T_07320	1.05e-89	282.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,2FN8J@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase family M3	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_91737_1	2340.JV46_07400	3.71e-152	446.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1J4UF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_91737_2	2340.JV46_07410	6.03e-90	265.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1J5QN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_91737_3	2340.JV46_07430	3.26e-48	155.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1J5YE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_246545_1	1298593.TOL_3243	5.51e-38	144.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XHH3@135619|Oceanospirillales	135619|Oceanospirillales	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_169640_1	1120965.AUBV01000019_gene1142	1.5e-73	250.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,4PNJW@976|Bacteroidetes	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
k59_192586_1	477228.YO5_13383	2.67e-11	72.8	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1Z1S7@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_153709_1	631362.Thi970DRAFT_03638	9.27e-45	153.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WWT5@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_14356_2	566461.SSFG_07394	3.04e-19	89.4	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_123138_1	706587.Desti_5601	1.91e-38	138.0	COG2241@1|root,COG2241@2|Bacteria,1NEMS@1224|Proteobacteria,42V5W@68525|delta/epsilon subdivisions,2WSDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.289	ko:K03399	ko00860,ko01100,map00860,map01100	-	R05813,R07775	RC00003,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k59_123138_2	1123020.AUIE01000031_gene2805	8.04e-07	51.6	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YE2N@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_14360_1	1121918.ARWE01000001_gene3254	4.71e-70	223.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_215657_1	682795.AciX8_4686	9.45e-28	107.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_91756_1	1535422.ND16A_1629	4.32e-08	59.7	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,1S719@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_68780_1	1165841.SULAR_05568	4.1e-112	331.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_45805_1	497964.CfE428DRAFT_0593	3.08e-41	154.0	COG3666@1|root,COG3666@2|Bacteria,46S8M@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_22550_1	685035.ADAE01000018_gene594	3.02e-41	154.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_76958_2	634499.EpC_27740	2.99e-06	49.3	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,3X6DX@551|Erwinia	1236|Gammaproteobacteria	E	T-protein	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,5.4.99.5	ko:K04517,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2925	ACT,CM_2,PDH
k59_69099_1	2340.JV46_03510	6.57e-57	190.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J4EJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740	PK,PK_C
k59_208312_1	3694.POPTR_1512s00200.1	1.57e-18	90.1	KOG1075@1|root,KOG1075@2759|Eukaryota,37TIF@33090|Viridiplantae,3G9IZ@35493|Streptophyta,4JJZN@91835|fabids	35493|Streptophyta	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,RVT_1,RVT_3,zf-RVT
k59_61306_1	631362.Thi970DRAFT_04205	9.71e-64	196.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1WYPN@135613|Chromatiales	135613|Chromatiales	C	Iron--sulfur cluster insertion protein erpA	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
k59_185208_1	1218173.BALCAV_0203625	1.75e-26	108.0	COG0679@1|root,COG0679@2|Bacteria,1TQCR@1239|Firmicutes,4HBKF@91061|Bacilli,1ZECC@1386|Bacillus	91061|Bacilli	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	-
k59_208313_1	511062.GU3_11050	8.8e-08	52.8	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,1RQ1I@1236|Gammaproteobacteria,1Y5IU@135624|Aeromonadales	135624|Aeromonadales	C	4Fe-4S binding domain	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5
k59_208313_2	765911.Thivi_4244	6.29e-96	287.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,1RNHT@1236|Gammaproteobacteria,1WY71@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S binding domain	-	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
k59_131071_1	1163617.SCD_n01153	4.44e-61	202.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_246909_1	446462.Amir_3602	4.42e-08	57.4	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,PP-binding,Thioesterase
k59_246909_2	377629.TERTU_2330	2.51e-24	102.0	COG2220@1|root,COG2220@2|Bacteria,1R4BX@1224|Proteobacteria,1RS4A@1236|Gammaproteobacteria,2PPGR@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
k59_45824_1	595494.Tola_3096	8.58e-08	52.8	COG1309@1|root,COG1309@2|Bacteria,1N11B@1224|Proteobacteria,1S8PU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_45824_2	1232683.ADIMK_0523	7.12e-60	196.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,465UD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Pyrophosphatase	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096	MazG
k59_169999_1	204669.Acid345_1576	4.93e-144	422.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_45825_1	2340.JV46_11930	3.62e-61	199.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1J4U9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	antiporter	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_208329_1	483219.LILAB_33120	1.65e-47	174.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
k59_246911_1	2340.JV46_12600	3.19e-89	281.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J8MI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_223908_1	1191460.F959_02433	2.14e-81	249.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,1RYEE@1236|Gammaproteobacteria,3NM8Q@468|Moraxellaceae	1236|Gammaproteobacteria	V	Restriction endonuclease	mrr	GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	HARE-HTH,Mrr_N,Mrr_cat
k59_154114_1	395493.BegalDRAFT_2604	1.94e-105	316.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_30524_1	2340.JV46_05440	2.61e-99	312.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1J8EA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_38410_1	998674.ATTE01000001_gene2740	1.25e-63	209.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales	72273|Thiotrichales	L	Exonuclease C-terminal	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k59_138560_1	1167006.UWK_01356	7.26e-31	129.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,42TR0@68525|delta/epsilon subdivisions,2WQ94@28221|Deltaproteobacteria,2MQ09@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_hydro_8,Glyco_trans_2_3,Glycos_transf_2,PilZ
k59_138560_2	1157708.KB907450_gene5703	3.82e-05	53.1	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,2VHPF@28216|Betaproteobacteria,4AB26@80864|Comamonadaceae	28216|Betaproteobacteria	M	Bacterial cellulose synthase subunit	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB
k59_177187_1	1137799.GZ78_28925	2.44e-69	212.0	COG1943@1|root,COG1943@2|Bacteria,1RI1H@1224|Proteobacteria,1T1BV@1236|Gammaproteobacteria,1XQ50@135619|Oceanospirillales	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_215997_2	1165841.SULAR_09789	1.1e-11	60.8	COG0792@1|root,COG0792@2|Bacteria,1Q27V@1224|Proteobacteria,42V4E@68525|delta/epsilon subdivisions,2YQJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_38412_1	313596.RB2501_06480	4.68e-133	383.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_161909_1	313596.RB2501_03725	3.09e-19	82.0	2C8TJ@1|root,32RMV@2|Bacteria,4NSAA@976|Bacteroidetes,1I54A@117743|Flavobacteriia	976|Bacteroidetes	S	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_192983_1	1165841.SULAR_09939	4.4e-52	167.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2YNX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_61326_1	985255.APHJ01000028_gene988	4.05e-24	99.4	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia,2P5TT@244698|Gillisia	976|Bacteroidetes	M	SIS domain	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_61326_2	313596.RB2501_11727	1.64e-170	496.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_231281_1	1167006.UWK_01769	2.09e-43	157.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2MIA7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_7290_1	502025.Hoch_6162	2.66e-15	81.6	COG3146@1|root,COG3146@2|Bacteria,1PD7R@1224|Proteobacteria,43E5F@68525|delta/epsilon subdivisions,2WZSD@28221|Deltaproteobacteria,2Z2NA@29|Myxococcales	28221|Deltaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_30534_1	283166.BH02320	2.09e-51	182.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,48TBN@772|Bartonellaceae	28211|Alphaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
k59_30536_1	95619.PM1_0218015	3.48e-83	272.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k59_100256_1	1122226.AUHX01000012_gene1232	3e-100	304.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_223911_1	1165841.SULAR_10289	1.28e-106	318.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2YN2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_239394_1	348824.LPU83_0884	4.44e-07	53.1	COG1595@1|root,COG1595@2|Bacteria,1RDJD@1224|Proteobacteria,2U8XJ@28211|Alphaproteobacteria,4B8JY@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_126761_1	448385.sce4136	1.93e-96	317.0	COG3321@1|root,COG3321@2|Bacteria,1Q52Y@1224|Proteobacteria,43A3Z@68525|delta/epsilon subdivisions,2XA2T@28221|Deltaproteobacteria,2YTU6@29|Myxococcales	28221|Deltaproteobacteria	Q	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_165486_1	1122132.AQYH01000002_gene1283	1.3e-110	335.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,4BAGU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_149743_1	1168034.FH5T_15545	1.71e-211	603.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,2FMEB@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_87881_1	631362.Thi970DRAFT_04894	2.51e-70	222.0	295V5@1|root,2ZT65@2|Bacteria,1REG0@1224|Proteobacteria,1S9HA@1236|Gammaproteobacteria,1WYWE@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103341_1	1499967.BAYZ01000090_gene4960	1.55e-64	213.0	COG1249@1|root,COG1249@2|Bacteria,2NNTI@2323|unclassified Bacteria	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_180922_1	497964.CfE428DRAFT_5037	1.72e-66	216.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_72390_1	105559.Nwat_0032	5.88e-50	164.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1WY33@135613|Chromatiales	135613|Chromatiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_18115_1	1197906.CAJQ02000034_gene2708	4.31e-61	201.0	COG5361@1|root,COG5361@2|Bacteria,1PB8E@1224|Proteobacteria,2U4FU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_72391_1	1188256.BASI01000001_gene926	5.23e-59	202.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2U4S4@28211|Alphaproteobacteria,3FDJN@34008|Rhodovulum	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_203971_1	96561.Dole_1930	6.2e-62	199.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_165499_1	1122917.KB899667_gene3620	5.57e-15	76.6	COG1621@1|root,COG3291@1|root,COG3934@1|root,COG4124@1|root,COG1621@2|Bacteria,COG3291@2|Bacteria,COG3934@2|Bacteria,COG4124@2|Bacteria,1V19K@1239|Firmicutes,4IT6T@91061|Bacilli,26WJK@186822|Paenibacillaceae	91061|Bacilli	G	Carbohydrate binding domain (family 11)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11,CBM_4_9,SLH
k59_111171_1	1165841.SULAR_01713	2.85e-124	362.0	COG0811@1|root,COG0811@2|Bacteria,1QUIX@1224|Proteobacteria,42MTG@68525|delta/epsilon subdivisions,2YMAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_227133_1	523791.Kkor_0856	2.61e-50	166.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1XIRE@135619|Oceanospirillales	135619|Oceanospirillales	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
k59_227133_2	1280390.CBQR020000138_gene3373	9.85e-09	57.8	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4HE7X@91061|Bacilli,26U8P@186822|Paenibacillaceae	91061|Bacilli	S	Pyrophosphatase	ppaX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_157575_1	313596.RB2501_01795	4.37e-69	221.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1HX4E@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_157575_2	1121875.KB907546_gene2616	5.19e-57	190.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,4NG1I@976|Bacteroidetes,1HXHP@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_111182_1	2340.JV46_18640	4.14e-55	188.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1J4ZF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_126781_3	388051.AUFE01000035_gene4020	2.86e-126	380.0	COG4653@1|root,COG4653@2|Bacteria	2|Bacteria	G	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_capsid
k59_126781_4	172088.AUGA01000082_gene6217	1.14e-11	68.9	COG3740@1|root,COG3740@2|Bacteria,1NBQ9@1224|Proteobacteria,2UK6T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Caudovirus prohead serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78
k59_111183_1	999141.GME_02410	4.7e-41	140.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1XJKR@135619|Oceanospirillales	135619|Oceanospirillales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_119022_1	396588.Tgr7_0636	2.09e-114	341.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM cytochrome c oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_111185_1	240016.ABIZ01000001_gene2307	1.14e-59	196.0	COG2805@1|root,COG2805@2|Bacteria,46UF2@74201|Verrucomicrobia,2ITJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_180944_1	591167.Sfla_0158	1.94e-45	166.0	COG1032@1|root,COG1032@2|Bacteria,2HGPR@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	-	-	-	ko:K18537,ko:K21224	ko01059,ko01130,map01059,map01130	M00831	R11389	RC03430	ko00000,ko00001,ko00002	-	-	-	B12-binding,Radical_SAM
k59_173083_1	595460.RRSWK_00154	3.77e-28	118.0	COG1232@1|root,COG1232@2|Bacteria,2IWT1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
k59_242701_1	349521.HCH_04818	4.5e-38	145.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1XKCN@135619|Oceanospirillales	135619|Oceanospirillales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_64758_1	1112216.JH594425_gene1244	3.79e-11	69.3	COG2911@1|root,COG2931@1|root,COG2982@1|root,COG3637@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3637@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K0IP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,He_PIG,HemolysinCabind
k59_203985_1	1042377.AFPJ01000025_gene612	7.58e-28	108.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,466ZZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG2755 Lysophospholipase L1 and related esterases	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
k59_235134_1	1120983.KB894574_gene1103	6.11e-19	93.2	COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,2TQXT@28211|Alphaproteobacteria,1JPX6@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_119026_1	1121448.DGI_2966	2.8e-05	46.6	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42M4Y@68525|delta/epsilon subdivisions,2WKKD@28221|Deltaproteobacteria,2MG10@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_119026_2	1242864.D187_000885	2.59e-06	53.9	COG0515@1|root,COG0515@2|Bacteria,1QX3Z@1224|Proteobacteria,430FI@68525|delta/epsilon subdivisions,2WVPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_149770_1	398767.Glov_3649	1.25e-38	138.0	COG2073@1|root,COG2073@2|Bacteria,1MWE6@1224|Proteobacteria,42U93@68525|delta/epsilon subdivisions,2WQKX@28221|Deltaproteobacteria,43T4U@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Cobalamin synthesis G C-terminus	-	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N
k59_149770_2	395493.BegalDRAFT_1119	5.46e-92	280.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,45ZSB@72273|Thiotrichales	72273|Thiotrichales	M	Arabinose 5-phosphate isomerase	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_180949_1	1218076.BAYB01000008_gene1750	0.000194	44.3	COG2885@1|root,COG2885@2|Bacteria,1P1AB@1224|Proteobacteria,2W0GG@28216|Betaproteobacteria,1K3F2@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_180949_2	580332.Slit_1782	6.87e-26	103.0	COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Response_reg
k59_203988_1	292459.STH3276	6.27e-08	59.3	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_18138_1	1165841.SULAR_06843	6.4e-113	330.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2YMHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_180953_1	1123399.AQVE01000042_gene1326	7.06e-41	140.0	COG0454@1|root,COG0454@2|Bacteria,1QUS5@1224|Proteobacteria,1RRHY@1236|Gammaproteobacteria,4630T@72273|Thiotrichales	72273|Thiotrichales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_219549_1	616991.JPOO01000001_gene3325	8.21e-73	228.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HZ28@117743|Flavobacteriia,23IF4@178469|Arenibacter	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_165526_1	1165841.SULAR_00085	1.61e-99	301.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_142160_1	118005.AWNK01000012_gene1	3.19e-98	299.0	COG1186@1|root,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_165533_1	1283300.ATXB01000001_gene2403	4.29e-84	264.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria,1XE3M@135618|Methylococcales	135618|Methylococcales	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
k59_72426_1	1168034.FH5T_01510	2.88e-74	248.0	COG0577@1|root,COG0577@2|Bacteria,4NZYZ@976|Bacteroidetes,2FWFC@200643|Bacteroidia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_103365_1	395493.BegalDRAFT_0361	5.86e-71	224.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,4606H@72273|Thiotrichales	72273|Thiotrichales	P	CBS domain	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_111203_1	1237149.C900_03021	6.34e-61	204.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_56968_1	395493.BegalDRAFT_2839	6.13e-66	204.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,46188@72273|Thiotrichales	72273|Thiotrichales	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k59_41633_2	1449351.RISW2_14775	3.12e-09	56.6	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,4KP22@93682|Roseivivax	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	nolR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22042	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k59_72428_1	395493.BegalDRAFT_1069	1.8e-32	130.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K07678	ko00230,ko02020,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02025,map02026,map04113,map04213,map05111	M00475,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,dCache_1
k59_56971_1	1443665.JACA01000041_gene1508	2.94e-40	147.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1HXF9@117743|Flavobacteriia,2YKNW@290174|Aquimarina	976|Bacteroidetes	EH	Rieske [2Fe-2S] domain	-	-	1.2.5.1,2.2.1.6	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R03145,R04672,R04673,R08648	RC00027,RC00106,RC00860,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_56971_2	1121948.AUAC01000003_gene2928	1.97e-19	83.6	COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria,4409B@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
k59_41634_1	326298.Suden_1457	3.53e-42	148.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_157582_1	395493.BegalDRAFT_2859	1.24e-09	59.3	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_72437_1	56107.Cylst_1420	1.16e-11	65.5	COG0454@1|root,COG0456@2|Bacteria,1GEIS@1117|Cyanobacteria	1117|Cyanobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80299_1	1209072.ALBT01000052_gene554	1.75e-35	142.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1FGEP@10|Cellvibrio	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4131)	ycaI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_119046_1	1387312.BAUS01000012_gene2158	1.65e-128	373.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,2KMFN@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Putative methyltransferase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_196436_1	696281.Desru_0342	6.25e-35	130.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,26039@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM cysteine desulfurase family protein	csd2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_196436_2	278963.ATWD01000001_gene1708	3.27e-31	122.0	COG0476@1|root,COG0476@2|Bacteria,3Y2HZ@57723|Acidobacteria,2JHXP@204432|Acidobacteriia	204432|Acidobacteriia	H	MoeZ MoeB	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_142174_1	1165841.SULAR_00475	1.73e-95	288.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2YMMP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_56980_1	1049564.TevJSym_ao00260	5.48e-44	162.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1J4G3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iG2583_1286.G2583_0058	OstA,OstA_C
k59_188574_1	1168034.FH5T_05410	2.58e-21	89.4	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,2FMP9@200643|Bacteroidia	976|Bacteroidetes	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_188574_2	385682.AFSL01000006_gene2377	1.98e-27	109.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,3XJIK@558415|Marinilabiliaceae	976|Bacteroidetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_150166_1	1077285.AGDG01000020_gene847	8.67e-84	267.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,2FN8J@200643|Bacteroidia,4AKU2@815|Bacteroidaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_49596_1	41431.PCC8801_2158	2.01e-47	160.0	2EABA@1|root,334FH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
k59_57329_1	1165841.SULAR_05188	1.09e-138	401.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2YMKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_212125_1	497964.CfE428DRAFT_4943	5.72e-19	90.5	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_158007_2	392499.Swit_0789	1.12e-12	74.3	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K3GP@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_26450_1	1089547.KB913013_gene2988	6.23e-35	139.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
k59_103707_1	1165841.SULAR_09569	9.85e-171	484.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_142625_1	222891.NSE_0671	4.75e-31	124.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,47ET6@766|Rickettsiales	766|Rickettsiales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_230729_2	313606.M23134_05548	2.04e-27	111.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
k59_29940_1	382464.ABSI01000013_gene1550	1.88e-09	58.9	COG2010@1|root,COG2010@2|Bacteria,46WR0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68584_1	1123399.AQVE01000001_gene670	1.13e-64	218.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,460A3@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_14156_1	1122602.ATXP01000005_gene2008	3.23e-07	52.8	COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,1W898@1268|Micrococcaceae	201174|Actinobacteria	H	The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are	thiF	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_91612_1	1177154.Y5S_01217	3.37e-139	403.0	COG2801@1|root,COG2801@2|Bacteria,1MVQ9@1224|Proteobacteria,1RR2M@1236|Gammaproteobacteria,1XQJB@135619|Oceanospirillales	135619|Oceanospirillales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_146422_1	471870.BACINT_01655	4.98e-83	268.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,2FNRE@200643|Bacteroidia,4AMHK@815|Bacteroidaceae	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_68588_1	344747.PM8797T_16308	3.57e-32	125.0	COG0397@1|root,COG0397@2|Bacteria,2J08F@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_68588_2	153948.NAL212_0446	3.73e-08	55.5	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,371TK@32003|Nitrosomonadales	28216|Betaproteobacteria	H	HemY protein N-terminus	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_12
k59_114958_1	387093.SUN_1836	4.47e-99	300.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2YMK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
k59_52987_1	794903.OPIT5_19160	3.87e-18	90.5	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,CUB,Calx-beta,DUF3739,Haemagg_act,SdrD_B
k59_230754_1	1155718.KB891907_gene886	3.63e-13	74.3	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
k59_29954_2	4565.Traes_2AL_33F114DA3.1	2.43e-169	484.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,3GEEJ@35493|Streptophyta,3KME8@4447|Liliopsida,3IAIW@38820|Poales	35493|Streptophyta	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cox1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k59_107031_1	991905.SL003B_0686	3.56e-62	204.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,4BSFU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_200282_1	1219065.VPR01S_10_00610	2.42e-06	53.1	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XUST@135623|Vibrionales	135623|Vibrionales	M	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm	skp	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_200282_2	2340.JV46_14980	5.04e-13	68.2	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1J4CD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_184711_1	870187.Thini_2460	3.49e-37	135.0	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S9ZC@1236|Gammaproteobacteria,46185@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF3299)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3299
k59_60760_1	1165841.SULAR_04302	1.72e-116	350.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_200283_1	290512.Paes_1431	1.11e-23	95.9	COG0572@1|root,COG0572@2|Bacteria,1FEHY@1090|Chlorobi	1090|Chlorobi	H	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
k59_200283_2	565653.EGBG_02840	6.31e-20	90.9	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HD7Z@91061|Bacilli,4B0IH@81852|Enterococcaceae	91061|Bacilli	G	Glycosyl hydrolase family 65, N-terminal domain	trePP	-	2.4.1.216,2.4.1.8	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_99634_1	1121875.KB907553_gene98	1.78e-79	258.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_246429_1	387093.SUN_1468	1.29e-42	152.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42YVP@68525|delta/epsilon subdivisions,2YRC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_215458_1	1323663.AROI01000009_gene3708	4.12e-87	268.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	Z012_08285	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_52996_1	1111732.AZOD01000030_gene1367	5.94e-20	94.7	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1X3TM@135614|Xanthomonadales	135614|Xanthomonadales	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_122902_1	980584.AFPB01000168_gene1921	2.12e-30	120.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1HXBZ@117743|Flavobacteriia,405TN@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	GTP-binding GTPase Middle Region	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_246430_1	309807.SRU_1616	3.28e-08	56.6	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1FJ4K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_246430_2	477228.YO5_13413	2.42e-49	166.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1Z1ZW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_223362_1	1121405.dsmv_2856	3.84e-135	406.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_238838_1	870187.Thini_0477	2.27e-182	512.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k59_138035_2	1165841.SULAR_05948	6.19e-43	156.0	28N8G@1|root,2ZBCV@2|Bacteria,1NMB1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114975_1	395493.BegalDRAFT_1892	1.28e-98	302.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,4605J@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_29980_1	1408304.JAHA01000019_gene2927	6.55e-40	137.0	COG2030@1|root,COG2030@2|Bacteria,1VBAU@1239|Firmicutes,25D25@186801|Clostridia,4BZE5@830|Butyrivibrio	186801|Clostridia	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_246431_1	1382356.JQMP01000003_gene1431	9.55e-97	299.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_246431_2	1124982.MSI_10470	8.18e-09	57.8	COG0653@1|root,COG0653@2|Bacteria,2J5UR@203691|Spirochaetes	203691|Spirochaetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_153549_1	2340.JV46_10650	2.79e-14	71.2	COG3383@1|root,COG3383@2|Bacteria,1MXTC@1224|Proteobacteria,1RZDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase	-	-	1.12.1.2	ko:K18006,ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
k59_153549_2	697282.Mettu_1512	5.15e-93	275.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,1XDM0@135618|Methylococcales	135618|Methylococcales	C	PFAM NADH ubiquinone	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
k59_153549_3	1121035.AUCH01000013_gene3091	1.63e-06	48.9	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,2KVAX@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_161397_1	639282.DEFDS_1544	2.18e-19	93.2	COG0840@1|root,COG0840@2|Bacteria,2GEW0@200930|Deferribacteres	200930|Deferribacteres	NT	SMART chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,MCPsignal,dCache_3
k59_114978_2	264731.PRU_1665	0.000313	45.4	COG0810@1|root,COG0810@2|Bacteria,4PKZJ@976|Bacteroidetes	976|Bacteroidetes	M	Pfam:DUF1625	-	-	-	-	-	-	-	-	-	-	-	-	TMEM43
k59_29981_1	1168034.FH5T_10910	2.44e-130	382.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,2FMTV@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_22019_1	1122134.KB893651_gene1852	6.27e-63	204.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XHV3@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_45308_1	1380380.JIAX01000012_gene335	7.81e-18	79.7	COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,2U5RY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Repressor involved in choline regulation of the bet genes	betI	-	-	ko:K02167	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_6,TetR_N
k59_45308_2	349102.Rsph17025_2313	6.07e-69	218.0	COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,2TRV8@28211|Alphaproteobacteria,1FB4Y@1060|Rhodobacter	28211|Alphaproteobacteria	E	of ABC-type glycine betaine transport system	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k59_83916_1	1265503.KB905166_gene652	7.49e-26	111.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169507_1	1165841.SULAR_05308	2.01e-82	248.0	2AIDI@1|root,31TAR@2|Bacteria,1QR0P@1224|Proteobacteria,42TWA@68525|delta/epsilon subdivisions,2YSYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilO
k59_200315_1	387093.SUN_1363	1.23e-22	97.1	COG1752@1|root,COG1752@2|Bacteria,1NCAA@1224|Proteobacteria,430CE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_200315_2	1165841.SULAR_00660	4.08e-127	368.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,42RG9@68525|delta/epsilon subdivisions,2YMVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transcriptional regulator, ModE family	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
k59_207767_1	1165841.SULAR_09774	2.13e-105	311.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2YN1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_22032_1	575540.Isop_2004	1.23e-51	184.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2IYQE@203682|Planctomycetes	203682|Planctomycetes	IQ	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
k59_223368_1	521045.Kole_0975	2.07e-08	68.6	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	HSP70,OmpA,VWA
k59_207782_1	1165841.SULAR_00710	3.67e-114	362.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_238892_1	1121272.KB903272_gene116	2.78e-23	97.1	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,4D8KH@85008|Micromonosporales	201174|Actinobacteria	GM	Nad-dependent epimerase dehydratase	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_14613_2	1453500.AT05_05120	1.82e-36	132.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia	976|Bacteroidetes	V	Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_223787_1	395493.BegalDRAFT_3503	1.87e-14	79.3	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24,TIR_2
k59_208163_1	1168034.FH5T_02050	2.35e-89	271.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_14617_1	270374.MELB17_13512	4.6e-54	173.0	COG0288@1|root,COG0288@2|Bacteria,1R3SC@1224|Proteobacteria,1RRB4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_161785_1	1123377.AUIV01000003_gene1849	5.57e-83	256.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1X3UD@135614|Xanthomonadales	135614|Xanthomonadales	H	Belongs to the prokaryotic GSH synthase family	gshB	GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_161786_1	177439.DP2742	3.47e-55	188.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2MJW6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_45690_1	886293.Sinac_2040	1.49e-32	129.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_14628_1	395493.BegalDRAFT_3279	2.02e-98	295.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_246791_1	1165841.SULAR_00695	6.35e-104	319.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2YMYH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_208176_1	948565.AFFP02000001_gene1165	1.01e-17	86.7	COG2369@1|root,COG2369@2|Bacteria,1PH12@1224|Proteobacteria,1T6BN@1236|Gammaproteobacteria,1Y9TA@135625|Pasteurellales	135625|Pasteurellales	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_7158_1	1042375.AFPL01000018_gene297	3.82e-50	170.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,464KZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_7158_2	857087.Metme_1472	1.13e-21	88.2	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XFS7@135618|Methylococcales	135618|Methylococcales	K	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
k59_7158_3	2340.JV46_22260	3.86e-71	228.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1J4DF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcHS_1320.EcHS_A4240,iPC815.YPO3728	AICARFT_IMPCHas,MGS
k59_246795_2	1392540.P256_02053	5.91e-35	124.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,3NN44@468|Moraxellaceae	1236|Gammaproteobacteria	KT	Response regulator receiver domain	pilG	-	-	ko:K02657,ko:K03413	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_185785_2	1385521.N803_10470	5.06e-16	80.9	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4FE32@85021|Intrasporangiaceae	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
k59_77437_1	1042376.AFPK01000027_gene2286	3.8e-136	397.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1HXW8@117743|Flavobacteriia,406SG@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Catalyzes the interconversion of D-xylose to D-xylulose	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
k59_100659_2	1480694.DC28_10220	1.77e-25	109.0	COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,2J59H@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
k59_62005_1	326298.Suden_1353	5.27e-23	90.1	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,42VMA@68525|delta/epsilon subdivisions,2YQAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
k59_62005_2	697282.Mettu_2912	4.85e-17	74.7	2EMFR@1|root,33F4G@2|Bacteria,1NJ55@1224|Proteobacteria,1SW6Q@1236|Gammaproteobacteria,1XFX6@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154833_1	1545915.JROG01000004_gene2223	9.97e-85	262.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2K02R@204457|Sphingomonadales	204457|Sphingomonadales	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_154833_2	521674.Plim_2392	7.75e-16	77.4	COG2146@1|root,COG2151@1|root,COG2146@2|Bacteria,COG2151@2|Bacteria,2J020@203682|Planctomycetes	203682|Planctomycetes	P	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P,Rieske
k59_46471_1	1165841.SULAR_05483	5.14e-112	340.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_23277_1	1168034.FH5T_09700	5.25e-87	257.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,2FT6A@200643|Bacteroidia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_193494_1	1114972.AUAW01000017_gene2668	1.03e-31	130.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,4HA4I@91061|Bacilli,3F5BC@33958|Lactobacillaceae	91061|Bacilli	Q	4-hydroxyphenylacetate	hpaH	-	1.14.14.8,1.14.14.9	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	-	R02698,R03299,R09517	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
k59_162533_1	506534.Rhein_2340	0.000273	48.1	COG4254@1|root,COG4254@2|Bacteria,1RJR0@1224|Proteobacteria,1S8WR@1236|Gammaproteobacteria,1X238@135613|Chromatiales	135613|Chromatiales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
k59_23280_1	395493.BegalDRAFT_1709	3.99e-117	352.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,45ZYV@72273|Thiotrichales	72273|Thiotrichales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_193511_3	1165841.SULAR_08142	1.53e-35	132.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,42MWP@68525|delta/epsilon subdivisions,2YNEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_147078_1	1266925.JHVX01000006_gene2151	3.48e-28	112.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,372G8@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
k59_170315_1	566466.NOR53_3392	8.57e-50	172.0	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1J5QJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA	rlmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.172,2.1.1.174	ko:K00564,ko:K11391	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
k59_239935_1	1120970.AUBZ01000027_gene1510	5.48e-58	191.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,4644R@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2340	AIRS,AIRS_C
k59_162553_1	1165841.SULAR_10099	1.95e-103	307.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2YMGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_170321_1	335283.Neut_1127	1.63e-92	285.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,3729N@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_123858_1	1349822.NSB1T_03565	2.05e-80	261.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,22WPI@171551|Porphyromonadaceae	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_224498_1	1165841.SULAR_09609	1.92e-101	299.0	COG1387@1|root,COG1387@2|Bacteria,1MX8T@1224|Proteobacteria,43BI2@68525|delta/epsilon subdivisions,2YT8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
k59_139455_1	1165841.SULAR_06118	7.1e-104	311.0	COG4775@1|root,COG4775@2|Bacteria,1R536@1224|Proteobacteria	1224|Proteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_131627_1	1165841.SULAR_00690	1.19e-98	314.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_62017_1	522373.Smlt3648	1.18e-79	259.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales	135614|Xanthomonadales	I	converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k59_69726_1	1161401.ASJA01000014_gene1048	3.07e-52	171.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,2TUKA@28211|Alphaproteobacteria,43ZT1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_46489_1	765910.MARPU_10595	4.23e-100	323.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales	135613|Chromatiales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_224511_1	2340.JV46_07260	9.43e-38	128.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1J6C1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_224511_2	243233.MCA2360	3.25e-89	265.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1XEFF@135618|Methylococcales	135618|Methylococcales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_232235_1	1121935.AQXX01000122_gene5617	5.85e-53	189.0	COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_131646_1	1444309.JAQG01000017_gene741	2.34e-43	162.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,Thioesterase
k59_154864_1	395493.BegalDRAFT_2840	1.58e-58	190.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,463HR@72273|Thiotrichales	72273|Thiotrichales	H	HPr Serine kinase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpr_kinase_C
k59_62033_1	1165841.SULAR_06268	2.78e-99	292.0	COG1305@1|root,COG1305@2|Bacteria,1Q2I2@1224|Proteobacteria,42VRK@68525|delta/epsilon subdivisions,2YQHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_62033_2	1165841.SULAR_06263	1.79e-18	80.1	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,42TJ0@68525|delta/epsilon subdivisions,2YPZ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_208996_1	1123508.JH636444_gene5300	1.44e-19	89.0	COG0284@1|root,COG0284@2|Bacteria,2IXSF@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_85200_1	395493.BegalDRAFT_3002	4.24e-73	229.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,460E1@72273|Thiotrichales	72273|Thiotrichales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_116_1	1165841.SULAR_00510	3.74e-120	356.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2YMFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_154874_2	997346.HMPREF9374_2720	2.37e-58	192.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,27BH8@186824|Thermoactinomycetaceae	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_131654_1	1168034.FH5T_10250	5.43e-49	174.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_62039_1	1121012.AUKX01000006_gene324	9.71e-29	107.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1HYH3@117743|Flavobacteriia,23H1M@178469|Arenibacter	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_62039_2	313596.RB2501_08245	4.3e-48	160.0	2C0PB@1|root,331E0@2|Bacteria,4NUMG@976|Bacteroidetes,1I58I@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_7831_1	1121396.KB893056_gene2640	2.88e-45	163.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WMD3@28221|Deltaproteobacteria,2MMTW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_108447_1	1121889.AUDM01000002_gene441	3.48e-77	233.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,1I1FM@117743|Flavobacteriia,2P0A2@237|Flavobacterium	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
k59_108447_2	398720.MED217_15515	6.63e-14	67.8	COG5642@1|root,COG5642@2|Bacteria,4NN76@976|Bacteroidetes,1I1NV@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
k59_31150_1	1243664.CAVL020000011_gene4404	1.12e-12	65.1	COG2030@1|root,COG2030@2|Bacteria,1V6MY@1239|Firmicutes,4HJ4K@91061|Bacilli,1ZHNF@1386|Bacillus	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_31150_2	395963.Bind_0202	1.32e-05	48.5	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,2TRK4@28211|Alphaproteobacteria,3NC87@45404|Beijerinckiaceae	28211|Alphaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141
k59_139496_1	2340.JV46_26840	2.4e-123	359.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1J4ND@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z0994	BATS,Radical_SAM
k59_139496_2	870187.Thini_2037	2.75e-21	92.8	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4602X@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_77455_1	313596.RB2501_05880	6.48e-90	267.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_54309_2	491952.Mar181_2412	6.28e-22	92.8	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,1S6SU@1236|Gammaproteobacteria,1XS89@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
k59_92992_1	743721.Psesu_0338	4.35e-59	198.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1X4FV@135614|Xanthomonadales	135614|Xanthomonadales	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_77457_2	1122194.AUHU01000003_gene2120	1.01e-35	139.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
k59_139855_2	1168034.FH5T_20105	3.9e-36	128.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
k59_70059_1	384765.SIAM614_02581	2.93e-53	184.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_101071_1	395493.BegalDRAFT_0393	1.35e-135	393.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,45ZNK@72273|Thiotrichales	72273|Thiotrichales	NU	PFAM Type II IV secretion system protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_139866_1	1134474.O59_003655	6.93e-20	90.1	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RZ1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	K -dependent Na Ca exchanger related-protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_139866_2	353496.LBU_1070	1.86e-05	46.2	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,3F7RM@33958|Lactobacillaceae	91061|Bacilli	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_8262_1	395493.BegalDRAFT_1569	3.25e-43	155.0	COG3156@1|root,COG3156@2|Bacteria,1RIW9@1224|Proteobacteria	1224|Proteobacteria	U	Type II secretion system (T2SS), protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_77829_1	300852.55773331	4.4e-47	163.0	COG3391@1|root,COG3391@2|Bacteria,1WICY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_217210_1	1123400.KB904813_gene3089	3.09e-123	355.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	(ABC) transporter	yhdZ	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.21	ko:K02028,ko:K02029,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	iJN746.PP_1300	ABC_tran
k59_193881_1	713586.KB900536_gene1624	1.91e-29	111.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	yafP	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_193881_2	713587.THITH_12240	1.08e-26	108.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_217211_1	1121104.AQXH01000003_gene437	1.13e-119	364.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_15937_1	313603.FB2170_05910	1.24e-31	121.0	COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,1HYBV@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
k59_54700_2	1168034.FH5T_11860	2.12e-90	272.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,2FKZ3@200643|Bacteroidia	976|Bacteroidetes	S	Hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
k59_240311_1	1122179.KB890497_gene2751	4.05e-13	77.4	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes,1IYDP@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_116576_1	550540.Fbal_0091	4.47e-65	211.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_241418_1	1198452.Jab_1c20820	1.56e-23	105.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria,478GF@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_110008_1	935557.ATYB01000009_gene619	3.07e-55	186.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TTAK@28211|Alphaproteobacteria,4B8X8@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	7-keto-8-aminopelargonate synthetase and related enzymes	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_210490_2	1265313.HRUBRA_00017	2.19e-12	72.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1J4NS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_117765_1	2340.JV46_16120	4.12e-136	422.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1J52Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_179654_1	313603.FB2170_02545	3.69e-47	168.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_94639_1	572477.Alvin_1995	4.02e-90	297.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k59_55819_2	42565.FP66_02670	9.98e-55	183.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XH6E@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_125541_1	1121405.dsmv_2552	7.67e-56	186.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MHRE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_125541_2	933262.AXAM01000040_gene1228	4.91e-40	134.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2MK8A@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_210495_1	404380.Gbem_3278	8.7e-57	194.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_241439_1	161156.JQKW01000010_gene385	1.48e-24	102.0	COG1624@1|root,COG1624@2|Bacteria,2GGVH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
k59_141005_1	292415.Tbd_1516	1.65e-22	90.5	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
k59_141005_2	1266925.JHVX01000003_gene449	2.73e-109	336.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,372IA@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_102184_1	1121405.dsmv_1209	5.99e-42	146.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,42RA9@68525|delta/epsilon subdivisions,2WQIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k59_241442_1	1469948.JPNB01000002_gene3389	5.83e-34	132.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,36DSQ@31979|Clostridiaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1793_1	1006006.Mcup_1539	5.07e-15	79.0	COG0247@1|root,arCOG00333@2157|Archaea,2XSQS@28889|Crenarchaeota	28889|Crenarchaeota	C	Cysteine-rich domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
k59_86789_1	1433126.BN938_2410	4.1e-29	113.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,2FMYA@200643|Bacteroidia,22V71@171550|Rikenellaceae	976|Bacteroidetes	S	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
k59_9555_1	395961.Cyan7425_3064	1.13e-68	221.0	COG0183@1|root,COG0183@2|Bacteria,1G0C7@1117|Cyanobacteria,3KHAU@43988|Cyanothece	1117|Cyanobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_117769_3	926569.ANT_22640	2.73e-15	78.2	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wblJ	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_102190_1	395493.BegalDRAFT_1401	2.24e-80	251.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,1RSA6@1236|Gammaproteobacteria,45ZTC@72273|Thiotrichales	72273|Thiotrichales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_156341_2	1165841.SULAR_00260	2.63e-140	396.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2YNVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_164110_1	202954.BBNK01000001_gene562	1.21e-54	191.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,3NJA4@468|Moraxellaceae	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_9557_1	666685.R2APBS1_1251	5.95e-18	90.1	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1X3D2@135614|Xanthomonadales	135614|Xanthomonadales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k59_17087_1	1165841.SULAR_01578	4.03e-116	336.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2YNTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_17087_2	653733.Selin_0712	3.96e-08	55.1	COG0694@1|root,COG0822@1|root,COG1251@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nifU	-	1.7.1.15	ko:K00362,ko:K13819	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_117776_1	880070.Cycma_3554	6.18e-13	75.9	COG4198@1|root,COG4198@2|Bacteria,4NGWT@976|Bacteroidetes,47MM8@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_210509_2	1380380.JIAX01000008_gene2023	3.23e-24	103.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Malic enzyme	dme	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_233935_1	395493.BegalDRAFT_0849	3.41e-81	270.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,LprI,MG1
k59_218388_1	1165841.SULAR_00650	9.02e-60	188.0	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,42UEQ@68525|delta/epsilon subdivisions,2YPZQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_79141_1	395493.BegalDRAFT_1441	8.3e-10	64.7	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,461IM@72273|Thiotrichales	72273|Thiotrichales	T	response regulator	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg,SBP_bac_3
k59_71203_1	313628.LNTAR_24319	3.9e-43	153.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	mscS	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_195086_1	1049564.TevJSym_ac00090	2.39e-162	467.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
k59_233943_1	1121859.KB890738_gene3122	3.19e-52	182.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_187304_1	1165841.SULAR_03782	1.06e-109	341.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_195087_1	1028800.RG540_PA10390	1.63e-65	213.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,4BDDJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_133156_1	1128912.GMES_2069	2.84e-128	378.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,4641X@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	oxidase subunit 1	cydA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iPC815.YPO1117,iSFxv_1172.SFxv_0621,iS_1188.S0577	Cyt_bd_oxida_I
k59_171899_1	1250278.JQNQ01000001_gene1434	7.79e-18	82.0	COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,1HY83@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_48188_1	502025.Hoch_3196	1.42e-79	251.0	COG1668@1|root,COG1668@2|Bacteria,1NK4G@1224|Proteobacteria,43B65@68525|delta/epsilon subdivisions,2X6JP@28221|Deltaproteobacteria,2Z3BG@29|Myxococcales	28221|Deltaproteobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2
k59_195093_1	765912.Thimo_2794	4.93e-72	229.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_179684_1	497964.CfE428DRAFT_4946	1.35e-48	162.0	2EK8J@1|root,33DYX@2|Bacteria,46VTQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_241476_1	459495.SPLC1_S200370	9.9e-48	179.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG5000@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg,dCache_1
k59_156828_2	469618.FVAG_01551	1.28e-60	197.0	COG1692@1|root,COG1692@2|Bacteria,378NB@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_126093_1	472759.Nhal_0099	1.99e-56	198.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_71679_1	103690.17133046	1.99e-25	103.0	COG2988@1|root,COG2988@2|Bacteria,1G2BY@1117|Cyanobacteria,1HTRU@1161|Nostocales	1117|Cyanobacteria	E	aspartoacylase activity	aspA	-	3.5.1.15	ko:K01437	ko00250,ko00340,ko01100,map00250,map00340,map01100	-	R00488,R00526	RC00064,RC00165,RC00300,RC00323	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k59_71679_3	1165841.SULAR_06623	3.47e-83	247.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_241932_1	452637.Oter_3166	2.58e-88	273.0	28H52@1|root,2Z7HQ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_17534_1	2340.JV46_29020	1.11e-74	237.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
k59_87181_1	4081.Solyc01g007320.2.1	0.0	910.0	COG0055@1|root,COG0355@1|root,KOG1350@2759|Eukaryota,KOG1758@2759|Eukaryota,37K5M@33090|Viridiplantae,3GCIP@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit beta	atpB	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_DE_N,ATP-synt_ab,ATP-synt_ab_N
k59_87181_2	3702.ATCG00470.1	1.37e-77	232.0	COG0355@1|root,KOG1758@2759|Eukaryota,37UFP@33090|Viridiplantae,3GIN2@35493|Streptophyta	35493|Streptophyta	C	ATP synthase epsilon chain	atpE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009526,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009941,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_241934_1	765911.Thivi_1736	3.38e-22	90.5	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1WVXJ@135613|Chromatiales	135613|Chromatiales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_241934_2	292415.Tbd_2563	3.14e-56	186.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1KRC9@119069|Hydrogenophilales	119069|Hydrogenophilales	CH	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_10029_1	1168034.FH5T_13665	1.57e-34	125.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,2FN6E@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_10029_2	1168034.FH5T_13670	2.78e-41	144.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia	976|Bacteroidetes	S	Von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
k59_110507_1	313628.LNTAR_11691	2.76e-40	154.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_87184_1	706436.HMPREF9074_07894	0.000115	50.4	COG4935@1|root,COG5184@1|root,COG4935@2|Bacteria,COG5184@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,1ER48@1016|Capnocytophaga	976|Bacteroidetes	O	Thrombospondin type 3	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
k59_210987_1	998674.ATTE01000001_gene3082	1.58e-26	107.0	COG0714@1|root,COG0714@2|Bacteria,1RJBX@1224|Proteobacteria,1S87A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	ATPase, AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_25375_1	2340.JV46_07780	5.7e-36	124.0	COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria,1RXXW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	reductase beta subunit	aprB	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4,Fer4_9
k59_25375_2	1123393.KB891317_gene2439	4.42e-81	247.0	2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,2W0AA@28216|Betaproteobacteria,1KS9S@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_71686_1	1384056.N787_09975	4.77e-48	158.0	2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,1S8M3@1236|Gammaproteobacteria,1XAU1@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_195610_1	768671.ThimaDRAFT_3135	7.27e-105	318.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWWZ@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
k59_210991_1	1449048.JQKU01000027_gene5377	1.45e-12	72.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,234GG@1762|Mycobacteriaceae	201174|Actinobacteria	GL	Ribonuclease	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
k59_187898_1	1265505.ATUG01000002_gene1532	2.1e-61	195.0	COG3910@1|root,COG3910@2|Bacteria,1MZSY@1224|Proteobacteria,42R25@68525|delta/epsilon subdivisions,2WN2C@28221|Deltaproteobacteria,2MJIF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
k59_218851_1	1123508.JH636440_gene2791	2.34e-12	73.6	COG2010@1|root,COG2010@2|Bacteria,2IZC1@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_110518_1	1165841.SULAR_09749	1.82e-29	114.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_110518_2	1165841.SULAR_09754	2.06e-59	189.0	COG3751@1|root,COG3751@2|Bacteria,1Q4MK@1224|Proteobacteria,42ZFP@68525|delta/epsilon subdivisions,2YRNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_2319_1	583345.Mmol_2274	1.12e-08	58.5	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,2KN6M@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
k59_203329_1	367737.Abu_2150	3.27e-81	246.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2YP0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_40969_1	762376.AXYL_02641	2.55e-68	216.0	COG3384@1|root,COG3384@2|Bacteria,1PUF4@1224|Proteobacteria,2VZW8@28216|Betaproteobacteria,3T6P8@506|Alcaligenaceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.74,1.13.11.76	ko:K15059	ko00627,ko01120,map00627,map01120	-	R05405	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_187902_1	870187.Thini_4336	7.9e-30	119.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RS9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_203331_1	28258.KP05_02290	1.16e-05	46.2	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_195624_1	1165841.SULAR_02333	2.1e-108	332.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GGDEF,PAS_9,dCache_3
k59_211002_1	1263831.F543_10610	2.31e-20	95.1	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1Y7V4@135625|Pasteurellales	135625|Pasteurellales	FP	Belongs to the GppA Ppx family	ppx	GO:0003674,GO:0003824,GO:0004309,GO:0006082,GO:0006793,GO:0006797,GO:0006798,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0071704,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_141433_1	1165841.SULAR_02948	2.71e-130	382.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_118376_1	945713.IALB_1666	1.02e-49	179.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
k59_211004_1	1265505.ATUG01000002_gene1234	5.01e-23	102.0	COG1196@1|root,COG1196@2|Bacteria,1MVMQ@1224|Proteobacteria,42NF4@68525|delta/epsilon subdivisions,2WIMP@28221|Deltaproteobacteria,2MJAB@213118|Desulfobacterales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10060_1	862514.HMPREF0623_0867	1.57e-18	79.3	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_10060_2	999423.HMPREF9161_01576	1.9e-43	146.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4H1V0@909932|Negativicutes	909932|Negativicutes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_64072_1	1165841.SULAR_00165	2.39e-84	255.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2YMZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_64072_2	1165841.SULAR_00170	6.75e-50	159.0	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,42VKI@68525|delta/epsilon subdivisions,2YQD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
k59_2329_1	2340.JV46_13120	6.2e-123	366.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,1RQK5@1236|Gammaproteobacteria,1J4SZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k59_226477_1	1189612.A33Q_2380	2.11e-42	159.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_156864_1	37682.EMT11274	5.78e-12	71.2	KOG4658@1|root,KOG4658@2759|Eukaryota,37JN7@33090|Viridiplantae,3GAV6@35493|Streptophyta,3KXEB@4447|Liliopsida,3IB1A@38820|Poales	35493|Streptophyta	T	disease resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,NB-ARC
k59_25407_1	1165841.SULAR_10149	8.08e-14	70.1	COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,43BSV@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_25407_2	1268635.Loa_01323	1.64e-24	105.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,1PF0N@1224|Proteobacteria,1RWSK@1236|Gammaproteobacteria,1JFVD@118969|Legionellales	118969|Legionellales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_87217_1	1123228.AUIH01000096_gene1756	1.3e-84	260.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XIXM@135619|Oceanospirillales	135619|Oceanospirillales	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_187919_2	472759.Nhal_4003	1.66e-29	112.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria,1WWIN@135613|Chromatiales	135613|Chromatiales	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_195641_2	1121472.AQWN01000009_gene407	1.63e-05	49.3	COG1652@1|root,COG1652@2|Bacteria,1VAPH@1239|Firmicutes,24N1D@186801|Clostridia,2670R@186807|Peptococcaceae	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_187920_1	270374.MELB17_22535	9.44e-86	268.0	COG4467@1|root,COG4467@2|Bacteria,1QW8C@1224|Proteobacteria,1S2JX@1236|Gammaproteobacteria,46BUT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_56319_1	391619.PGA1_c18040	2.68e-15	73.6	COG1028@1|root,COG1028@2|Bacteria,1RA3U@1224|Proteobacteria,2U640@28211|Alphaproteobacteria,34G9S@302485|Phaeobacter	28211|Alphaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_17556_1	1237149.C900_05343	3.57e-56	190.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47K4A@768503|Cytophagia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	gabD	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_149085_1	1168034.FH5T_03195	2.76e-82	256.0	COG0251@1|root,COG0251@2|Bacteria,4NEVA@976|Bacteroidetes,2FN38@200643|Bacteroidia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102671_1	1172190.M947_06400	1.56e-24	107.0	COG1470@1|root,COG3210@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,42NZJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
k59_156875_2	1165841.SULAR_06848	7.04e-84	263.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_226487_1	398512.JQKC01000052_gene2672	2.59e-101	307.0	2C8MZ@1|root,2ZA7T@2|Bacteria,1UFFD@1239|Firmicutes,24F4E@186801|Clostridia,3WN3M@541000|Ruminococcaceae	186801|Clostridia	S	Family of unknown function (DUF5309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5309
k59_126155_1	765913.ThidrDRAFT_2740	6.47e-57	204.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WXP6@135613|Chromatiales	135613|Chromatiales	O	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_71719_1	1173025.GEI7407_0433	1.95e-16	84.0	COG3209@1|root,COG3210@1|root,COG3240@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3240@2|Bacteria	2|Bacteria	I	lipase activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,Calx-beta,Lipase_GDSL,RHS_repeat
k59_141447_1	1049564.TevJSym_ad01120	3.16e-85	280.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1J5AR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1643 HrpA-like helicases	hrpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_102680_1	981223.AIED01000075_gene718	1.79e-15	75.5	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,3NK51@468|Moraxellaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN746.PP_0436	S4,tRNA-synt_1b
k59_196350_1	314285.KT71_08620	3.23e-106	316.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1J9WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_80228_1	1499967.BAYZ01000032_gene1153	4.19e-25	103.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2NQ28@2323|unclassified Bacteria	2|Bacteria	L	Integrase core domain	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_28,HTH_Tnp_1,rve,rve_3
k59_80228_2	1137799.GZ78_14485	4.97e-102	305.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_2941_1	335543.Sfum_1768	9.57e-49	176.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,42UA0@68525|delta/epsilon subdivisions,2WS4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
k59_118943_1	1121481.AUAS01000003_gene3778	3.87e-32	118.0	COG4636@1|root,COG4636@2|Bacteria,4NNM9@976|Bacteroidetes,47Q0X@768503|Cytophagia	976|Bacteroidetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_180864_1	1123326.JFBL01000014_gene240	1.51e-32	130.0	COG3209@1|root,COG3209@2|Bacteria,1R0C4@1224|Proteobacteria,43CUG@68525|delta/epsilon subdivisions,2YSH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41569_1	768671.ThimaDRAFT_3563	5.39e-84	270.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXY0@135613|Chromatiales	135613|Chromatiales	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
k59_134246_1	1172190.M947_09630	6.61e-13	67.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2YNFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_134246_2	387093.SUN_1760	1.19e-22	95.9	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2YMC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_165417_1	640081.Dsui_1299	1.83e-57	187.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,2KW1M@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k59_173013_1	365044.Pnap_1978	3.57e-79	247.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,4AD0Z@80864|Comamonadaceae	28216|Betaproteobacteria	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbM	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_173013_2	395493.BegalDRAFT_3380	4.5e-88	266.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_219460_1	1210884.HG799472_gene14782	3.69e-28	116.0	COG0801@1|root,COG1028@1|root,COG0801@2|Bacteria,COG1028@2|Bacteria,2IYIH@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	HPPK,adh_short_C2
k59_111117_1	1168034.FH5T_06990	9.07e-97	294.0	COG1305@1|root,COG1305@2|Bacteria,4NEZ3@976|Bacteroidetes,2G2JQ@200643|Bacteroidia	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_18070_1	313596.RB2501_08715	3.92e-59	196.0	COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,1HY19@117743|Flavobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GT87
k59_87824_1	1239415.CM001837_gene2286	5.88e-87	276.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia,37E38@326319|Dokdonia	976|Bacteroidetes	C	Aconitase family (aconitate hydratase)	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_87824_2	1250232.JQNJ01000001_gene2429	6.76e-12	63.5	COG0526@1|root,COG0526@2|Bacteria,4NNPY@976|Bacteroidetes,1I228@117743|Flavobacteriia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_142079_1	396588.Tgr7_2286	3.91e-74	231.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,1WW3S@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k59_142079_2	1255043.TVNIR_2718	6.39e-13	68.6	COG0790@1|root,COG0790@2|Bacteria,1PFSC@1224|Proteobacteria,1TJ65@1236|Gammaproteobacteria,1WY15@135613|Chromatiales	135613|Chromatiales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_165427_1	329726.AM1_4438	3.01e-18	85.9	COG3335@1|root,COG3335@2|Bacteria,1G6I9@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
k59_103307_1	177439.DP0730	1.07e-41	145.0	28P1J@1|root,2ZBXX@2|Bacteria,1REYC@1224|Proteobacteria,42RM0@68525|delta/epsilon subdivisions,2WNN9@28221|Deltaproteobacteria,2MJS1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyrimidine dimer DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,Pyr_excise
k59_103308_1	1056820.KB900641_gene481	7.29e-44	154.0	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,2PN89@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
k59_157513_1	1380394.JADL01000012_gene880	5.94e-51	170.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria,2JQH4@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_56886_1	1165841.SULAR_09559	2.03e-112	327.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42N4V@68525|delta/epsilon subdivisions,2YN04@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	rluA	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_87827_1	134676.ACPL_4110	2.19e-48	180.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4D8GT@85008|Micromonosporales	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_227091_1	1165841.SULAR_04853	4.1e-74	248.0	COG2911@1|root,COG2911@2|Bacteria,1PBYT@1224|Proteobacteria,42T65@68525|delta/epsilon subdivisions,2YPPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_219469_1	118173.KB235914_gene3164	1.16e-79	251.0	COG0033@1|root,COG0033@2|Bacteria,1G0ZB@1117|Cyanobacteria,1H9DN@1150|Oscillatoriales	1117|Cyanobacteria	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_34036_1	1396418.BATQ01000103_gene5522	2.75e-135	403.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_80246_1	1122134.KB893651_gene2183	4.09e-82	256.0	COG0106@1|root,COG0139@1|root,COG0140@1|root,COG0106@2|Bacteria,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XK33@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,PRA-CH,PRA-PH
k59_2968_1	56110.Oscil6304_3621	6.65e-21	98.2	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1FZXP@1117|Cyanobacteria,1H71W@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HAMP,PAS,PAS_4,PAS_9,dCache_1
k59_235082_1	509190.Cseg_2941	2.01e-55	196.0	COG1629@1|root,COG1629@2|Bacteria,1MWTT@1224|Proteobacteria,2TURM@28211|Alphaproteobacteria,2KHK9@204458|Caulobacterales	204458|Caulobacterales	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_242658_1	796606.BMMGA3_03470	1.31e-12	72.8	COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus	91061|Bacilli	N	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_111125_1	1353537.TP2_01230	9.13e-69	226.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2XKWB@285107|Thioclava	28211|Alphaproteobacteria	I	functions in conversion of succinate to propionate	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_111125_2	2754.EH55_06205	0.000646	42.0	COG0281@1|root,COG0281@2|Bacteria,3T9QC@508458|Synergistetes	508458|Synergistetes	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
k59_2970_2	1168034.FH5T_06135	1.3e-126	375.0	COG2956@1|root,COG2956@2|Bacteria,4PNWA@976|Bacteroidetes,2G0ZI@200643|Bacteroidia	976|Bacteroidetes	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k59_111126_1	207954.MED92_15418	9.87e-69	226.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XH42@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
k59_203922_1	553217.ENHAE0001_0463	1.31e-33	124.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,3NJCY@468|Moraxellaceae	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
k59_203922_2	472759.Nhal_3951	1.24e-21	86.7	COG0636@1|root,COG0636@2|Bacteria,1R359@1224|Proteobacteria,1T63K@1236|Gammaproteobacteria,1X2WZ@135613|Chromatiales	135613|Chromatiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_34057_1	744985.HIMB59_00006830	7.69e-07	56.2	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,2U1SX@28211|Alphaproteobacteria,4BPZ2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
k59_157519_1	1168034.FH5T_04780	3.23e-135	391.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,2FN1B@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase, class I II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_103317_2	522306.CAP2UW1_0129	1.74e-44	159.0	COG3385@1|root,COG3385@2|Bacteria,1QFKR@1224|Proteobacteria	1224|Proteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_219490_1	111781.Lepto7376_1639	1.01e-74	259.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
k59_95716_1	1165841.SULAR_03782	7.31e-101	317.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_196381_1	501479.ACNW01000062_gene2740	4.71e-122	365.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_80255_1	1168034.FH5T_05595	2.3e-38	136.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,2FME3@200643|Bacteroidia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_80255_2	269798.CHU_1445	3.44e-21	86.7	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,47R35@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_64719_1	483216.BACEGG_01561	2.03e-12	68.9	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,2FPXJ@200643|Bacteroidia,4ANIW@815|Bacteroidaceae	976|Bacteroidetes	M	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
k59_10714_1	983545.Glaag_4086	3.67e-49	172.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,4648F@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG0339 Zn-dependent oligopeptidases	prlC	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_10714_2	1265313.HRUBRA_00106	9.76e-20	83.6	COG0720@1|root,COG0720@2|Bacteria,1N10D@1224|Proteobacteria,1SBJZ@1236|Gammaproteobacteria,1J65G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_56902_1	1165841.SULAR_01623	6.19e-195	548.0	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_56902_2	1165841.SULAR_01628	3.82e-62	191.0	COG2010@1|root,COG2010@2|Bacteria,1QA9H@1224|Proteobacteria,42VAH@68525|delta/epsilon subdivisions,2YQGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56902_3	1165841.SULAR_01638	2.95e-25	98.2	28QM5@1|root,3192M@2|Bacteria,1Q1JK@1224|Proteobacteria,42TV6@68525|delta/epsilon subdivisions,2YPT2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56902_4	1165841.SULAR_01638	1.37e-18	79.0	28QM5@1|root,3192M@2|Bacteria,1Q1JK@1224|Proteobacteria,42TV6@68525|delta/epsilon subdivisions,2YPT2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165470_1	572547.Amico_1216	3.66e-18	92.0	COG0790@1|root,COG0790@2|Bacteria,3TC57@508458|Synergistetes	508458|Synergistetes	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111133_1	395493.BegalDRAFT_2725	9.41e-15	75.9	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,1QZXQ@1224|Proteobacteria,1SZ7Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111133_2	686340.Metal_1022	1.73e-35	122.0	2E95X@1|root,333EM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103331_1	1415754.JQMK01000005_gene1800	8.56e-71	226.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,465C7@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_173041_1	4155.Migut.G00885.1.p	1.88e-122	350.0	KOG1721@1|root,KOG1721@2759|Eukaryota,38A9Z@33090|Viridiplantae,3GY91@35493|Streptophyta,44UXV@71274|asterids	35493|Streptophyta	S	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_72369_1	1219080.VEZ01S_21_01000	2.92e-05	45.8	COG2207@1|root,COG2207@2|Bacteria,1P4DA@1224|Proteobacteria,1S87M@1236|Gammaproteobacteria,1XWSP@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_18102_2	1208321.D104_10860	5.55e-107	318.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_103334_1	29306.JOBE01000002_gene2822	4.42e-36	146.0	COG1403@1|root,COG3209@1|root,COG1403@2|Bacteria,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN
k59_203946_1	926550.CLDAP_17390	1.91e-62	213.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,2G827@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_2992_1	1165841.SULAR_05748	1.07e-112	330.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_111141_1	1303518.CCALI_01884	2.02e-94	289.0	COG0821@1|root,COG0821@2|Bacteria	2|Bacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037	GcpE
k59_227111_1	1165841.SULAR_09119	5.33e-214	605.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_3357_1	1049564.TevJSym_as00540	8.12e-28	110.0	29QAQ@1|root,30B9W@2|Bacteria,1RGQ5@1224|Proteobacteria,1S5E4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_18447_1	283942.IL1926	5.03e-25	105.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,2QF13@267893|Idiomarinaceae	1236|Gammaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	acdP	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k59_103652_1	1049564.TevJSym_ab00480	1.7e-70	220.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
k59_103652_2	1380394.JADL01000001_gene2232	1.04e-19	84.3	COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,2U7WC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	CDP-archaeol synthase	-	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
k59_49564_1	713586.KB900536_gene2577	5.75e-21	97.8	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1WX6D@135613|Chromatiales	135613|Chromatiales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_103654_1	717785.HYPMC_2406	2.82e-46	155.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,3N6XD@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0260 family	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_57267_2	83406.HDN1F_11450	1.36e-32	125.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1J50K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_26379_1	2340.JV46_27580	7.69e-127	387.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	ttrA	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K08357,ko:K21307	ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020	-	R10149,R10150,R11487	RC00168,RC02823,RC03109	ko00000,ko00001,ko01000,ko02000	5.A.3.10,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_127136_1	395493.BegalDRAFT_0207	3.19e-60	209.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T4BF@1236|Gammaproteobacteria	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	chiS	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg,Y_Y_Y
k59_157969_1	595460.RRSWK_00694	0.000754	48.5	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_243015_1	568703.LGG_01561	5.31e-72	236.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae	91061|Bacilli	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_127140_1	387093.SUN_2382	1.5e-48	165.0	COG2067@1|root,COG2067@2|Bacteria,1RJIQ@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_173405_1	1122247.C731_2752	2.18e-20	89.4	COG3340@1|root,COG3340@2|Bacteria,2IC7Y@201174|Actinobacteria,234WT@1762|Mycobacteriaceae	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
k59_204358_1	765911.Thivi_1066	4.59e-86	271.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales	135613|Chromatiales	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
k59_34408_1	1168034.FH5T_10755	3.8e-116	361.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_103662_2	502025.Hoch_2090	2.26e-23	100.0	COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,42YAW@68525|delta/epsilon subdivisions,2WTPQ@28221|Deltaproteobacteria,2YU9D@29|Myxococcales	28221|Deltaproteobacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
k59_157974_1	1458861.A0A088C4A0_9CAUD	4.46e-12	72.0	4QAMU@10239|Viruses,4QV4U@35237|dsDNA viruses  no RNA stage,4QPEV@28883|Caudovirales,4QI0J@10662|Myoviridae	10662|Myoviridae	S	Baseplate J-like protein	-	GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025	-	-	-	-	-	-	-	-	-	-	-
k59_57279_1	1165841.SULAR_01175	2.76e-58	185.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
k59_57279_2	1165841.SULAR_01165	1.94e-14	73.9	COG4886@1|root,COG4886@2|Bacteria,1R9FD@1224|Proteobacteria,42XXN@68525|delta/epsilon subdivisions,2YQP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Leucine Rich repeats (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
k59_150114_1	745277.GRAQ_00689	0.000248	46.2	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,1S12R@1236|Gammaproteobacteria,3FGYY@34037|Rahnella	1236|Gammaproteobacteria	S	esterase of the alpha beta hydrolase fold	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
k59_134695_1	1048339.KB913029_gene4462	6.14e-18	83.6	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4EU7X@85013|Frankiales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
k59_83987_1	1453505.JASY01000005_gene1586	6.17e-12	72.4	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG3292@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia,2NS9E@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_138131_2	756499.Desde_3300	2.18e-09	59.3	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,261Z3@186807|Peptococcaceae	186801|Clostridia	H	PFAM Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
k59_176791_1	1165841.SULAR_03512	3.49e-70	221.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42PQE@68525|delta/epsilon subdivisions,2YNTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_115059_1	1168034.FH5T_05040	2.71e-114	340.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,2FMCR@200643|Bacteroidia	976|Bacteroidetes	S	HD domain protein	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_60898_1	1165841.SULAR_07013	3.58e-77	234.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_91690_1	387093.SUN_1149	7.78e-13	65.9	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,42RBT@68525|delta/epsilon subdivisions,2YNWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_91690_2	1165841.SULAR_05518	6.17e-81	256.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_91692_1	375286.mma_0542	9.18e-39	138.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,472T9@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k59_91692_2	1288298.rosmuc_01916	2.81e-09	59.3	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,46ND8@74030|Roseovarius	28211|Alphaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_76508_1	1242864.D187_007897	9.14e-56	179.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,42TDM@68525|delta/epsilon subdivisions,2WP8D@28221|Deltaproteobacteria,2YV8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
k59_76508_2	1515746.HR45_18770	6.36e-55	183.0	COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,1RV4C@1236|Gammaproteobacteria,2QESZ@267890|Shewanellaceae	1236|Gammaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_215570_1	768671.ThimaDRAFT_0765	9.31e-71	228.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,1WY2T@135613|Chromatiales	135613|Chromatiales	C	PFAM Nickel-dependent hydrogenase, large subunit	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
k59_99748_1	385682.AFSL01000003_gene1922	1.83e-148	424.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,2FM8V@200643|Bacteroidia,3XJ2G@558415|Marinilabiliaceae	976|Bacteroidetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_207897_1	1173264.KI913949_gene1576	1.83e-28	110.0	COG3415@1|root,COG3415@2|Bacteria,1G802@1117|Cyanobacteria	1117|Cyanobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32
k59_207897_2	768671.ThimaDRAFT_4427	2.63e-82	258.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,1S900@1236|Gammaproteobacteria,1WZQJ@135613|Chromatiales	135613|Chromatiales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_207914_1	1191523.MROS_1857	1.16e-33	136.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
k59_14264_1	237368.SCABRO_01442	1.38e-19	91.7	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_161483_1	1322246.BN4_11010	5.29e-65	220.0	COG3303@1|root,COG3303@2|Bacteria,1QXPE@1224|Proteobacteria,42NA5@68525|delta/epsilon subdivisions,2X4IA@28221|Deltaproteobacteria,2MEC4@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_22159_1	411901.BACCAC_02120	2.65e-07	58.9	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FWSR@200643|Bacteroidia,4AV24@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_22161_1	1168034.FH5T_18240	1.59e-151	438.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,2FMBN@200643|Bacteroidia	976|Bacteroidetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_161497_1	555778.Hneap_2110	2.48e-69	216.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1WWPE@135613|Chromatiales	135613|Chromatiales	G	HAD-superfamily hydrolase, subfamily IA, variant 3	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_91711_1	313596.RB2501_00441	5.33e-28	112.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,1HWRA@117743|Flavobacteriia	976|Bacteroidetes	G	COG0380 Trehalose-6-phosphate synthase	otsB	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
k59_91711_2	1121012.AUKX01000004_gene3497	1.91e-33	127.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,1HY70@117743|Flavobacteriia,23GE9@178469|Arenibacter	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
k59_246525_1	1165841.SULAR_09679	4.99e-132	394.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_131296_1	452637.Oter_2944	1.45e-120	352.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_53684_1	1168034.FH5T_05380	3.03e-44	146.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,2FM42@200643|Bacteroidia	976|Bacteroidetes	U	Biopolymer transport protein, ExbD	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_53684_2	1168034.FH5T_05385	6.1e-46	152.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_61504_1	395493.BegalDRAFT_2494	4.09e-103	311.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,45ZRR@72273|Thiotrichales	72273|Thiotrichales	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_138779_1	1165841.SULAR_00355	1.08e-235	655.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_247091_1	425104.Ssed_3583	1.7e-09	58.9	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,2QB6Y@267890|Shewanellaceae	1236|Gammaproteobacteria	CET	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
k59_247091_2	1121012.AUKX01000005_gene3647	9.97e-11	64.7	COG2367@1|root,COG2367@2|Bacteria,4NHT5@976|Bacteroidetes,1HWY4@117743|Flavobacteriia,23FMR@178469|Arenibacter	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
k59_38583_1	653733.Selin_0964	6.88e-33	131.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG2433@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG2433@2|Bacteria	2|Bacteria	T	PhoQ Sensor	cheB	-	2.1.1.80,2.7.7.65,3.1.1.61,3.5.1.44	ko:K00575,ko:K03412,ko:K03413,ko:K13590,ko:K13924	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GGDEF,HATPase_c,HWE_HK,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
k59_154276_2	497964.CfE428DRAFT_1385	2.39e-153	449.0	COG3344@1|root,COG3344@2|Bacteria,46SUD@74201|Verrucomicrobia	2|Bacteria	L	Group II intron maturase-specific domain protein	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_216155_1	243231.GSU0018	7.37e-75	241.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MID@68525|delta/epsilon subdivisions,2WJYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_123683_1	59689.fgenesh2_kg.2__723__ATCG00270.1	2.52e-264	723.0	2CNIT@1|root,2QWJF@2759|Eukaryota,37RZQ@33090|Viridiplantae,3GF68@35493|Streptophyta	35493|Streptophyta	C	Photosystem II (PSII) is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1 D2 (PsbA PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex	psbD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0010287,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	1.10.3.9	ko:K02706	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Photo_RC
k59_123683_2	4572.TRIUR3_00075-P1	8.6e-301	822.0	28ISP@1|root,2QR3X@2759|Eukaryota,37T53@33090|Viridiplantae,3G7SE@35493|Streptophyta,3KP6W@4447|Liliopsida,3IG0F@38820|Poales	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbC	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_224068_2	1349785.BAUG01000004_gene356	2.41e-46	157.0	COG3637@1|root,COG3637@2|Bacteria,4NX35@976|Bacteroidetes,1I9V6@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_7504_2	1168034.FH5T_13190	5.83e-25	96.7	COG1225@1|root,COG1225@2|Bacteria,4NXEC@976|Bacteroidetes,2FZPP@200643|Bacteroidia	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100371_1	316275.VSAL_I2433	7.48e-11	62.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XSE8@135623|Vibrionales	135623|Vibrionales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_100371_2	555778.Hneap_2183	1.34e-33	119.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1WYM1@135613|Chromatiales	135613|Chromatiales	U	TIGRFAM preprotein translocase, YajC subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_100371_3	1117647.M5M_01480	2.85e-25	99.8	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1J656@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325	CDP-OH_P_transf
k59_14895_1	396588.Tgr7_0206	2.3e-23	97.8	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,1WVUP@135613|Chromatiales	135613|Chromatiales	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_14895_2	2340.JV46_24690	1.64e-62	198.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1J7ZS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	soxA	-	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_131312_1	1165841.SULAR_01080	1.65e-102	325.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,42ZJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_162070_1	1232683.ADIMK_2850	7.62e-106	327.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1S02D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_177372_1	1168034.FH5T_20505	1.67e-81	256.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia	976|Bacteroidetes	O	peptidase Do	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
k59_107798_1	316058.RPB_3569	3.67e-35	137.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,3JTZ5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	MA20_07375	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_239546_1	279006.D9I6A7_9CAUD	1.18e-11	68.2	4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses  no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage T4-like capsid assembly protein (Gp20)	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_239546_2	1589733.A0A0C5AIT1_9CAUD	0.000164	44.3	4QAQQ@10239|Viruses,4QPBX@28883|Caudovirales,4QIBM@10662|Myoviridae	10662|Myoviridae	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_38599_1	396588.Tgr7_0902	1.45e-55	184.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales	135613|Chromatiales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
k59_38599_2	1198232.CYCME_0911	1.34e-13	65.5	COG3242@1|root,COG3242@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	yjeT	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
k59_38599_3	1121935.AQXX01000114_gene3278	1.24e-27	109.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1XIEV@135619|Oceanospirillales	135619|Oceanospirillales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_92305_2	1134474.O59_000144	3.3e-58	196.0	2DNBF@1|root,32WM0@2|Bacteria,1MYQR@1224|Proteobacteria,1S2GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53717_1	748280.NH8B_2436	8.25e-10	65.5	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQNU@206351|Neisseriales	206351|Neisseriales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4
k59_61525_1	2340.JV46_09630	3.49e-130	383.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_53721_1	1168034.FH5T_10250	1.26e-141	417.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_53721_2	1168034.FH5T_10245	9.71e-27	103.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,2FRI2@200643|Bacteroidia	976|Bacteroidetes	K	Chemotaxis protein CheY	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_231477_1	1279017.AQYJ01000023_gene3227	1.64e-72	226.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,46BKC@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_69333_1	643648.Slip_1471	7.56e-77	243.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,42JPD@68298|Syntrophomonadaceae	186801|Clostridia	I	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_2865_3	997829.HMPREF1121_00505	5.31e-28	111.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia,22WKX@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_188438_1	395493.BegalDRAFT_1631	2.5e-161	464.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,1RSFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_134170_2	760732.E5E470_9CAUD	1.58e-41	143.0	4QCXM@10239|Viruses,4QZZ5@35237|dsDNA viruses  no RNA stage,4QT8U@28883|Caudovirales,4QJ27@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103213_1	1165841.SULAR_09264	2.43e-44	150.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2YN8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_103213_2	1165841.SULAR_09269	6.12e-60	201.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_242587_1	1165841.SULAR_03762	2.43e-120	356.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_134174_1	313596.RB2501_01810	1.5e-133	386.0	COG2035@1|root,COG2035@2|Bacteria,4NDU1@976|Bacteroidetes,1HYB3@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF368
k59_103218_1	118168.MC7420_5261	2.52e-45	153.0	298Z8@1|root,2ZW30@2|Bacteria,1G5VW@1117|Cyanobacteria,1HAQT@1150|Oscillatoriales	1117|Cyanobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41524_1	1121405.dsmv_0890	9.28e-99	301.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MIDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein)	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_49081_1	4572.TRIUR3_25900-P1	2.93e-08	52.8	2D39H@1|root,2SQRI@2759|Eukaryota,380CP@33090|Viridiplantae,3GK7H@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111042_1	927658.AJUM01000037_gene1932	1.72e-51	167.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,2FU4Q@200643|Bacteroidia,3XK4D@558415|Marinilabiliaceae	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_227017_1	1449347.JQLN01000005_gene4584	0.000224	49.3	COG1020@1|root,COG1020@2|Bacteria,2IEI8@201174|Actinobacteria	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Condensation,PP-binding
k59_118883_1	1265503.KB905173_gene4127	4.88e-57	190.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,1RPWJ@1236|Gammaproteobacteria,2Q7I6@267889|Colwelliaceae	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_118883_2	1443665.JACA01000070_gene3192	8.2e-83	252.0	COG0823@1|root,COG0823@2|Bacteria,4NJN5@976|Bacteroidetes,1I0Y8@117743|Flavobacteriia,2YJ9X@290174|Aquimarina	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_33958_1	1210884.HG799473_gene14973	2.47e-45	165.0	COG3464@1|root,COG3464@2|Bacteria,2IZV3@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Uncharacterised protein family (UPF0236)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103232_1	994479.GL877883_gene7504	1.42e-19	92.8	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4DZQT@85010|Pseudonocardiales	201174|Actinobacteria	L	ATP-dependent DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_10655_1	313612.L8106_26892	2.64e-36	130.0	COG1943@1|root,COG1943@2|Bacteria,1G4NJ@1117|Cyanobacteria,1HB3A@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_134187_1	1165841.SULAR_06708	8.05e-48	158.0	COG0607@1|root,COG0607@2|Bacteria,1N45X@1224|Proteobacteria,42T79@68525|delta/epsilon subdivisions,2YPIK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_18022_1	1121405.dsmv_0691	1.58e-187	536.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_25962_1	138119.DSY0173	6.59e-14	78.6	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,261EJ@186807|Peptococcaceae	186801|Clostridia	V	NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_56809_1	243233.MCA1474	3.31e-83	259.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XEBP@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_18025_1	324057.Pjdr2_4573	9.45e-12	62.8	2DPNX@1|root,332TS@2|Bacteria,1VMJK@1239|Firmicutes,4HSMI@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188457_1	886293.Sinac_6266	7.55e-40	141.0	2DMFF@1|root,32R5F@2|Bacteria	2|Bacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_126647_1	1266925.JHVX01000009_gene54	6.64e-23	90.5	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,37304@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_126647_2	2340.JV46_02700	6.29e-87	267.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1J7KN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3	ko:K00113,ko:K11473	ko00564,ko00630,ko01100,ko01110,ko01120,ko01130,map00564,map00630,map01100,map01110,map01120,map01130	-	R00475,R00848	RC00029,RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
k59_41529_1	1038858.AXBA01000057_gene4931	4.31e-27	112.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3F1AV@335928|Xanthobacteraceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_188459_2	1168034.FH5T_07950	1.15e-37	140.0	COG4772@1|root,COG4772@2|Bacteria,4NF0U@976|Bacteroidetes,2FM7N@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_111464_1	882378.RBRH_00429	1.01e-27	116.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,Thioesterase
k59_34339_1	387093.SUN_1801	1.62e-75	234.0	COG2515@1|root,COG2515@2|Bacteria,1R87T@1224|Proteobacteria,42MPC@68525|delta/epsilon subdivisions,2YN3K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	1-aminocyclopropane-1-carboxylate deaminase	acd	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	-
k59_11024_1	1049564.TevJSym_ac00100	2.54e-112	333.0	2DBUZ@1|root,2ZB8W@2|Bacteria,1QWGF@1224|Proteobacteria,1SN24@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_134624_1	742767.HMPREF9456_00050	1.32e-32	116.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,2FSHU@200643|Bacteroidia,22Y1V@171551|Porphyromonadaceae	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_196735_1	1168034.FH5T_04910	3.59e-07	51.2	COG0726@1|root,COG0726@2|Bacteria,4NPJX@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_196735_2	1168034.FH5T_04915	1.73e-66	215.0	COG0454@1|root,COG0456@2|Bacteria,4NYFM@976|Bacteroidetes	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_3325_1	261292.Nit79A3_3310	1.12e-14	80.9	COG3540@1|root,COG3540@2|Bacteria,1PI5V@1224|Proteobacteria,2W6S3@28216|Betaproteobacteria,374GH@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
k59_150026_1	2340.JV46_28850	1.96e-107	317.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,1J63G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_227430_1	999611.KI421504_gene3358	7.97e-62	209.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,280B0@191028|Leisingera	28211|Alphaproteobacteria	I	Methylmalonyl-CoA mutase	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_57212_1	56780.SYN_01078	6.24e-42	142.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,43BPD@68525|delta/epsilon subdivisions,2X70Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
k59_57212_2	511.JT27_08705	2.49e-67	213.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,3T3RD@506|Alcaligenaceae	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_57212_3	326297.Sama_1090	3.71e-14	72.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,1S1WW@1236|Gammaproteobacteria,2Q9ZR@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
k59_157897_2	1165841.SULAR_01380	4.96e-65	202.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2YNF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 1	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_96020_1	641526.ADIWIN_2667	1.19e-53	191.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
k59_119340_1	1134445.AJJM01000033_gene3850	6.33e-09	62.0	COG1181@1|root,COG1181@2|Bacteria,2I32M@201174|Actinobacteria	201174|Actinobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
k59_26344_1	298386.PBPRA2936	1.09e-56	195.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales	135623|Vibrionales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k59_96021_1	985255.APHJ01000032_gene2750	3.29e-67	220.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia,2P6FM@244698|Gillisia	976|Bacteroidetes	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_235421_1	1120965.AUBV01000008_gene1931	3.7e-23	100.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,47KMG@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	tolB3	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_111468_2	1397528.Q671_16800	2.11e-27	114.0	COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,1S8TI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
k59_80544_1	1168034.FH5T_07180	7.73e-105	308.0	COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
k59_18398_1	1165841.SULAR_05178	7.65e-44	146.0	COG2834@1|root,COG2834@2|Bacteria,1PQ15@1224|Proteobacteria,42WEH@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_18398_2	1165841.SULAR_05183	2.88e-202	584.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_181231_1	903818.KI912268_gene2471	2.58e-22	98.6	COG1293@1|root,COG1293@2|Bacteria	2|Bacteria	K	actin binding	yloA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_80553_1	1165841.SULAR_04863	3.57e-64	203.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2YMSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iIT341.HP0961	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_80553_2	1165841.SULAR_04858	1.15e-13	70.5	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_134633_1	2340.JV46_24850	1.56e-55	184.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1J5CN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG4992 Ornithine acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_11038_1	1183438.GKIL_4230	1.83e-32	127.0	COG2244@1|root,COG2244@2|Bacteria,1GGFN@1117|Cyanobacteria	1117|Cyanobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_3
k59_88217_1	1123355.JHYO01000011_gene1420	4.15e-17	80.5	COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,36YF2@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
k59_227444_1	156889.Mmc1_2503	5.9e-77	244.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2TSH1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_11040_1	1168034.FH5T_19415	1.82e-86	275.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,2FQ61@200643|Bacteroidia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
k59_181241_1	509191.AEDB02000002_gene1299	5.28e-10	64.3	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHEA@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_235426_1	929558.SMGD1_0488	6.16e-68	213.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2YNAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_235426_2	511062.GU3_12860	1.67e-29	114.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1Y3X0@135624|Aeromonadales	135624|Aeromonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_227445_1	530564.Psta_2700	6.7e-48	166.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_242977_1	395493.BegalDRAFT_0394	1.2e-79	250.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,45ZSM@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_219854_1	1031711.RSPO_c02870	9.94e-11	60.5	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,1K6XN@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Lactoylglutathione lyase	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_219854_2	929558.SMGD1_1085	3.24e-39	141.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_11047_1	7668.SPU_003026-tr	9.77e-07	55.8	2D1AE@1|root,2SHBM@2759|Eukaryota,3AFP7@33154|Opisthokonta,3BY0Y@33208|Metazoa,3DET1@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17
k59_57232_1	313628.LNTAR_06519	7.92e-18	77.4	COG2076@1|root,COG2076@2|Bacteria	2|Bacteria	P	Multidrug Resistance protein	emrE	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
k59_57232_2	395493.BegalDRAFT_2869	1.82e-58	193.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,45ZRP@72273|Thiotrichales	72273|Thiotrichales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_227458_1	1450525.JATV01000008_gene731	5.81e-90	297.0	COG1361@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4PAKE@976|Bacteroidetes,1IN20@117743|Flavobacteriia,2NXAW@237|Flavobacterium	976|Bacteroidetes	MN	domain, Protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	-
k59_65041_1	1209072.ALBT01000024_gene3816	3.29e-25	110.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1FGR6@10|Cellvibrio	1236|Gammaproteobacteria	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
k59_150058_2	1168034.FH5T_04170	7.99e-80	264.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_238741_1	1396858.Q666_10605	1.26e-61	198.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,46489@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360	ACP_syn_III,ACP_syn_III_C
k59_238741_2	629265.PMA4326_29130	7.64e-12	64.7	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1Z5G6@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	I	Malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
k59_83798_1	1313421.JHBV01000041_gene3444	1.08e-25	109.0	COG1481@1|root,COG4995@1|root,COG1481@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes	976|Bacteroidetes	K	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
k59_45208_1	2340.JV46_21780	4.67e-72	219.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1J70E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_37759_1	1437448.AZRT01000188_gene4103	8.57e-19	87.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2TTW3@28211|Alphaproteobacteria,1J3KY@118882|Brucellaceae	28211|Alphaproteobacteria	V	Biotin-lipoyl like	yiaV	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
k59_37759_2	1385515.N791_13150	2.5e-18	90.1	COG3637@1|root,COG3637@2|Bacteria,1N7AR@1224|Proteobacteria,1SHEZ@1236|Gammaproteobacteria,1X5E1@135614|Xanthomonadales	135614|Xanthomonadales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_137939_1	593750.Metfor_1802	3.48e-17	77.0	COG1669@1|root,arCOG01206@2157|Archaea,2Y02Z@28890|Euryarchaeota,2NBEY@224756|Methanomicrobia	28890|Euryarchaeota	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
k59_137939_2	391009.Tmel_1695	3.82e-19	80.9	COG2361@1|root,COG2361@2|Bacteria,2GDEF@200918|Thermotogae	200918|Thermotogae	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
k59_45213_1	1121104.AQXH01000001_gene1614	9.51e-41	151.0	28PJE@1|root,2ZC90@2|Bacteria,4NJ5D@976|Bacteroidetes,1IX2U@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
k59_238747_1	1165841.SULAR_09689	2.55e-171	483.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2YMRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_106946_1	391587.KAOT1_02029	3.89e-17	84.7	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,1HXB1@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_37768_1	397290.C810_02028	1.13e-31	127.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,27IG2@186928|unclassified Lachnospiraceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_176594_1	1121405.dsmv_0559	5.68e-99	306.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MHKH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_215376_1	760192.Halhy_1923	0.000199	43.1	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,4NKPG@976|Bacteroidetes	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k59_230679_1	1168034.FH5T_10090	6.11e-86	279.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_52873_1	1165841.SULAR_03887	2.06e-36	123.0	2AN4M@1|root,31D2D@2|Bacteria,1QA3X@1224|Proteobacteria,433I5@68525|delta/epsilon subdivisions,2YSM0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45640_2	443254.Marpi_1669	1.89e-52	169.0	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_68949_1	313596.RB2501_08585	7.27e-91	293.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_177014_1	1237149.C900_04491	1.67e-57	206.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_38200_1	243233.MCA1433	2.72e-121	361.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,1XFN6@135618|Methylococcales	135618|Methylococcales	M	Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_161736_1	1283300.ATXB01000001_gene1199	4.28e-25	102.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hydrolase	yigB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
k59_161736_2	1187848.AJYQ01000006_gene668	7.48e-06	47.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1XSNT@135623|Vibrionales	135623|Vibrionales	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_185019_1	395493.BegalDRAFT_2434	1.66e-16	85.1	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,460ZS@72273|Thiotrichales	72273|Thiotrichales	D	Peptidase family M23	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
k59_185019_2	696747.NIES39_A00340	1.5e-35	130.0	COG1373@1|root,COG1373@2|Bacteria,1GHCV@1117|Cyanobacteria	1117|Cyanobacteria	S	ATPase (AAA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_185022_1	1265313.HRUBRA_02487	1.14e-48	164.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1J4UB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_185022_2	314285.KT71_00985	8.43e-74	225.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1J4KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_161742_1	932677.PAJ_2624	3.12e-38	144.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,3VZ1Y@53335|Pantoea	1236|Gammaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272,ko:K21344	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECH74115_1262.ECH74115_4363,iECSP_1301.ECSP_4025,iECs_1301.ECs3935,iPC815.YPO0654,iZ_1308.Z4405	CTP_transf_like,PfkB
k59_215815_1	1385935.N836_21545	5.1e-05	50.8	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_91929_1	1504981.KO116_4831	1.88e-158	452.0	COG3328@1|root,COG3328@2|Bacteria,1QE3G@1224|Proteobacteria,1TBD7@1236|Gammaproteobacteria,1XQDQ@135619|Oceanospirillales	135619|Oceanospirillales	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61179_1	1218076.BAYB01000021_gene3787	2.08e-67	217.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,1K2JZ@119060|Burkholderiaceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
k59_239219_1	387093.SUN_0481	7.63e-61	198.0	COG2951@1|root,COG2951@2|Bacteria,1PPIK@1224|Proteobacteria,43ABD@68525|delta/epsilon subdivisions,2YQXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_61182_1	1165841.SULAR_04382	1.05e-43	145.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2YQ20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EJ	GlutRNAGln amidotransferase subunit D	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_61182_2	1165841.SULAR_04392	7.51e-51	170.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,42Z0J@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	coproporphyrinogen III oxidase	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760	Coprogen_oxidas
k59_76785_3	445688.E3SNS2_9CAUD	1.39e-27	111.0	4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses  no RNA stage,4QPJE@28883|Caudovirales,4QI9Y@10662|Myoviridae	10662|Myoviridae	S	ATPase family associated with various cellular activities (AAA)	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_100060_1	1165841.SULAR_01718	8.39e-108	325.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1N68I@1224|Proteobacteria,43BAI@68525|delta/epsilon subdivisions,2YT7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_177035_1	1144319.PMI16_02849	3.8e-59	190.0	COG3826@1|root,COG3826@2|Bacteria,1MWVV@1224|Proteobacteria,2VHMX@28216|Betaproteobacteria,47322@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Oxygenase, catalysing oxidative methylation of damaged DNA	-	-	-	ko:K09990	-	-	-	-	ko00000	-	-	-	Oxygenase-NA
k59_107396_1	1123401.JHYQ01000002_gene2680	2.84e-47	160.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_107396_2	640081.Dsui_2211	3.05e-09	55.5	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,2KWKD@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_246765_3	438753.AZC_0427	8.73e-15	70.1	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria,3EZN6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_146863_1	203122.Sde_2045	3.7e-54	202.0	COG3210@1|root,COG3210@2|Bacteria,1QQD4@1224|Proteobacteria,1RZ1D@1236|Gammaproteobacteria,46BII@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192788_1	387093.SUN_1468	1.38e-122	366.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42YVP@68525|delta/epsilon subdivisions,2YRC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_208127_1	1131553.JIBI01000004_gene428	3.49e-28	118.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria,372F7@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c
k59_146869_1	1165841.SULAR_02443	1.97e-58	192.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_107397_1	1564096.A0A0A0YRA5_9CAUD	5.74e-59	204.0	4QHDM@10239|Viruses,4QRD0@28883|Caudovirales,4QI2W@10662|Myoviridae	10662|Myoviridae	S	Terminase-like family	-	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949	-	-	-	-	-	-	-	-	-	-	-
k59_246774_1	1198452.Jab_2c34390	8.56e-05	50.1	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,473G0@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_246774_2	1379698.RBG1_1C00001G0261	5.24e-17	76.3	COG0759@1|root,COG0759@2|Bacteria,2NQ30@2323|unclassified Bacteria	2|Bacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_76805_1	1168034.FH5T_06985	2.06e-98	290.0	COG0702@1|root,COG0702@2|Bacteria,4NGMR@976|Bacteroidetes	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_45662_1	314285.KT71_04640	6.07e-82	257.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1J5CG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_177037_2	331869.BAL199_15808	4.84e-16	79.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,4BQAJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_53372_1	1123257.AUFV01000001_gene1578	4.1e-71	224.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales	135614|Xanthomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_38235_1	338963.Pcar_0544	1.52e-96	317.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,43VRH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_115361_1	1178482.BJB45_04650	4.5e-56	189.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XI0Q@135619|Oceanospirillales	135619|Oceanospirillales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_246779_1	1168034.FH5T_09495	2.63e-131	375.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,2FN8E@200643|Bacteroidia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_7139_1	392499.Swit_3706	2.19e-72	235.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,2KEBC@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_200654_1	1121875.KB907546_gene2208	3.41e-155	448.0	COG1680@1|root,COG1680@2|Bacteria,4PI69@976|Bacteroidetes,1I0GH@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_7143_1	1249627.D779_2020	5.86e-30	109.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,1S5CH@1236|Gammaproteobacteria,1WY3N@135613|Chromatiales	135613|Chromatiales	S	Nitrogen fixation protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
k59_7143_2	870187.Thini_4022	2.27e-20	83.2	COG5420@1|root,COG5420@2|Bacteria,1N98S@1224|Proteobacteria,1SCVR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Uncharacterised protein family UPF0437	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
k59_7143_3	1485544.JQKP01000001_gene1008	1.15e-21	87.4	COG1143@1|root,COG1143@2|Bacteria,1N1SG@1224|Proteobacteria,2VT6Z@28216|Betaproteobacteria,44WJ1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S double cluster binding domain	fdxB	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
k59_68991_1	2340.JV46_23200	9.29e-54	170.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1J7C4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	bigR	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_68991_2	1442599.JAAN01000004_gene1074	5.03e-33	120.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1X737@135614|Xanthomonadales	135614|Xanthomonadales	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_68991_3	523791.Kkor_2294	2.04e-16	76.3	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XK48@135619|Oceanospirillales	135619|Oceanospirillales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_165080_1	95619.PM1_0201005	2.65e-81	247.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_103038_1	472759.Nhal_0779	7.68e-48	171.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,1RQRW@1236|Gammaproteobacteria,1WWNC@135613|Chromatiales	135613|Chromatiales	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
k59_103038_2	2340.JV46_13870	4.21e-35	124.0	2DZRC@1|root,32VGV@2|Bacteria,1N2PT@1224|Proteobacteria,1SQQ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
k59_56597_1	13035.Dacsa_1266	1.53e-23	99.0	COG4313@1|root,COG4313@2|Bacteria,1G150@1117|Cyanobacteria	1117|Cyanobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_126452_1	999611.KI421504_gene870	9.96e-11	62.0	COG1171@1|root,COG1171@2|Bacteria,1MW2Q@1224|Proteobacteria,2TTP9@28211|Alphaproteobacteria,27ZQ4@191028|Leisingera	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_10423_1	96561.Dole_0426	3.21e-113	346.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2MHU3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,sCache_3_2
k59_180572_1	323848.Nmul_A0723	1.89e-57	203.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VHNB@28216|Betaproteobacteria,371VU@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_64418_1	204669.Acid345_3980	7.98e-61	216.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_8
k59_226766_1	575540.Isop_0706	1.87e-21	102.0	COG1404@1|root,COG1404@2|Bacteria,2IZ64@203682|Planctomycetes	203682|Planctomycetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_211343_1	1301098.PKB_3082	6.3e-44	159.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C,RLAN,RimK
k59_64421_1	1049564.TevJSym_bp00060	4.36e-38	142.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08483,ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_64421_2	187272.Mlg_0427	4.87e-20	85.5	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales	135613|Chromatiales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_141770_1	1168034.FH5T_19415	9e-132	395.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,2FQ61@200643|Bacteroidia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
k59_173095_1	717231.Flexsi_0527	9.21e-06	54.7	COG2404@1|root,COG2404@2|Bacteria,2GF6S@200930|Deferribacteres	200930|Deferribacteres	S	DHHA1 domain	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
k59_95790_2	1165841.SULAR_00975	1.13e-37	127.0	COG2388@1|root,COG2388@2|Bacteria,1NKJW@1224|Proteobacteria	1224|Proteobacteria	S	-acetyltransferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG,GFA
k59_227164_1	45351.EDO46109	2.6e-47	174.0	KOG0621@1|root,KOG0621@2759|Eukaryota,38I3R@33154|Opisthokonta,3BBDE@33208|Metazoa	33208|Metazoa	M	phospholipid scrambling	PLSCR3	GO:0000981,GO:0000982,GO:0001077,GO:0001228,GO:0001775,GO:0002237,GO:0002252,GO:0002376,GO:0002520,GO:0002526,GO:0002682,GO:0002684,GO:0002694,GO:0003674,GO:0003700,GO:0005102,GO:0005154,GO:0005215,GO:0005319,GO:0005488,GO:0005509,GO:0005515,GO:0005548,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005794,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006575,GO:0006629,GO:0006644,GO:0006650,GO:0006658,GO:0006659,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006915,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0006955,GO:0007009,GO:0007154,GO:0007165,GO:0007275,GO:0007596,GO:0007599,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009611,GO:0009615,GO:0009617,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010256,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010876,GO:0010911,GO:0010912,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0015711,GO:0015748,GO:0015914,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0017121,GO:0017124,GO:0017128,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019899,GO:0019904,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030168,GO:0031012,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031974,GO:0031981,GO:0032091,GO:0032496,GO:0032501,GO:0032502,GO:0032774,GO:0032781,GO:0033003,GO:0033036,GO:0033500,GO:0033993,GO:0034097,GO:0034641,GO:0034645,GO:0034654,GO:0035455,GO:0035456,GO:0035556,GO:0042060,GO:0042221,GO:0042398,GO:0042592,GO:0042593,GO:0042609,GO:0042632,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043462,GO:0043900,GO:0043901,GO:0043903,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044271,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045017,GO:0045069,GO:0045071,GO:0045088,GO:0045089,GO:0045121,GO:0045893,GO:0045935,GO:0045944,GO:0046474,GO:0046483,GO:0046486,GO:0046872,GO:0048306,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048525,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050817,GO:0050865,GO:0050878,GO:0050896,GO:0051098,GO:0051100,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051254,GO:0051336,GO:0051345,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055088,GO:0055092,GO:0060255,GO:0060368,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070782,GO:0070851,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071396,GO:0071702,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090407,GO:0097035,GO:0097190,GO:0097193,GO:0097194,GO:0097659,GO:0098542,GO:0098589,GO:0098805,GO:0098857,GO:0140110,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701,GO:1902229,GO:1902231,GO:1902531,GO:1902533,GO:1902680,GO:1903506,GO:1903508,GO:1903900,GO:1903901,GO:2000112,GO:2000371,GO:2000373,GO:2001020,GO:2001022,GO:2001141,GO:2001233,GO:2001235,GO:2001242,GO:2001244	-	-	-	-	-	-	-	-	-	-	Scramblase
k59_188579_1	1387312.BAUS01000004_gene1467	1.03e-30	125.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,2KNG7@206350|Nitrosomonadales	206350|Nitrosomonadales	U	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
k59_10775_1	519989.ECTPHS_00275	1.86e-131	381.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RVJU@1236|Gammaproteobacteria,1WXJS@135613|Chromatiales	135613|Chromatiales	I	Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_142177_1	1172562.HCN_1385	3.98e-10	61.2	2E9B6@1|root,333J1@2|Bacteria,1NXIN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80304_1	1303518.CCALI_01724	1.2e-23	105.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
k59_26069_1	765913.ThidrDRAFT_3596	7.64e-64	202.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1X0NE@135613|Chromatiales	135613|Chromatiales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_87925_1	411476.BACOVA_01522	4.08e-75	235.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,2FMYA@200643|Bacteroidia,4AQBG@815|Bacteroidaceae	976|Bacteroidetes	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
k59_219581_1	96561.Dole_3172	2.98e-15	70.5	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MM5W@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_219581_2	1054213.HMPREF9946_04499	4.26e-10	61.2	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,2JQA2@204441|Rhodospirillales	204441|Rhodospirillales	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_72447_1	1307759.JOMJ01000004_gene3100	1.66e-71	239.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,42Q3U@68525|delta/epsilon subdivisions,2WJ18@28221|Deltaproteobacteria,2M9ZX@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188588_1	886377.Murru_0408	6.17e-62	203.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HWM7@117743|Flavobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_188588_2	391596.PBAL39_15164	6.34e-12	62.0	2E4IE@1|root,32ZDH@2|Bacteria,4NUR6@976|Bacteroidetes,1IU61@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
k59_188588_3	1121904.ARBP01000006_gene3779	6.19e-11	65.5	COG2831@1|root,COG2831@2|Bacteria,4PMYI@976|Bacteroidetes,47YEW@768503|Cytophagia	976|Bacteroidetes	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
k59_126845_1	990073.ATHU01000002_gene63	2.69e-13	76.3	COG0642@1|root,COG0642@2|Bacteria,1PZPT@1224|Proteobacteria,42QYI@68525|delta/epsilon subdivisions,2YP31@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,HisKA
k59_227167_1	2340.JV46_11990	1.76e-101	312.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1J4TI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_49234_1	439235.Dalk_3095	5.57e-71	218.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_49234_2	1165841.SULAR_00720	1.82e-29	111.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2YN34@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_149820_1	1397284.AYMN01000013_gene4464	8.29e-35	131.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,4044S@613|Serratia	1236|Gammaproteobacteria	S	Iron-sulfur cluster-binding domain	pqqE	GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_219593_2	1227739.Hsw_2124	1.38e-31	119.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,47JQX@768503|Cytophagia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_211751_1	471870.BACINT_01082	5.1e-23	91.7	2EBGM@1|root,335H7@2|Bacteria,4NVJG@976|Bacteroidetes,2FUX7@200643|Bacteroidia,4AS14@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4884)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4884
k59_103396_3	948071.S4S2D9_9CAUD	5.2e-108	334.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae	10744|Podoviridae	S	ribonucleoside-triphosphate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_227174_1	1134474.O59_001853	1.69e-125	395.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1FG63@10|Cellvibrio	1236|Gammaproteobacteria	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
k59_180993_1	946077.W5A_02040	3.58e-31	121.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_180993_2	313596.RB2501_08340	4.05e-20	84.3	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1I3ZS@117743|Flavobacteriia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
k59_111243_1	1123278.KB893562_gene3248	5.57e-64	209.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47K2Q@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
k59_49246_1	1165841.SULAR_09299	4.19e-53	167.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2YPHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_49246_2	1165841.SULAR_09294	4.17e-97	284.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_49246_3	1165841.SULAR_09289	5.14e-09	54.3	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2YPZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_87952_1	981369.JQMJ01000004_gene5756	2.95e-53	187.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,2NF2V@228398|Streptacidiphilus	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX2	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_165567_1	161934.XP_010681841.1	2.74e-22	95.9	28PJA@1|root,2QW7G@2759|Eukaryota,37N4G@33090|Viridiplantae,3GE4X@35493|Streptophyta	35493|Streptophyta	S	Serine threonine-protein phosphatase 7 long form homolog	-	-	5.1.3.5	ko:K12448	ko00520,ko01100,map00520,map01100	-	R01473	RC00528	ko00000,ko00001,ko01000	-	-	-	PMD
k59_188608_1	1150469.RSPPHO_02764	1e-42	161.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2TW04@28211|Alphaproteobacteria,2JQYW@204441|Rhodospirillales	204441|Rhodospirillales	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	nifA	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k59_103403_1	395493.BegalDRAFT_3259	2.91e-80	245.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,45ZU2@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_72467_2	765912.Thimo_2418	1.55e-35	128.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1WXW3@135613|Chromatiales	135613|Chromatiales	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_18175_1	2340.JV46_02640	8.74e-55	193.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1JB0I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_188613_1	1165841.SULAR_09944	3.4e-141	416.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_204075_1	1168289.AJKI01000044_gene35	1.28e-08	57.8	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,2FNIT@200643|Bacteroidia	976|Bacteroidetes	T	PAS domain S-box protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
k59_204075_2	1168034.FH5T_15540	8.96e-32	111.0	2DFUX@1|root,2ZT8Y@2|Bacteria,4P92B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165570_1	2340.JV46_24710	3.7e-27	103.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S4ZT@1236|Gammaproteobacteria,1JBSY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ,TAT_signal
k59_165570_2	2340.JV46_24720	1.3e-50	163.0	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,1JAGD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	soxX	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_242750_1	349521.HCH_07028	9.32e-63	216.0	COG2373@1|root,COG3755@1|root,COG2373@2|Bacteria,COG3755@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,LprI,MG1
k59_219620_2	401053.AciPR4_1556	7.24e-28	113.0	COG3279@1|root,COG3279@2|Bacteria,3Y6RT@57723|Acidobacteria,2JJK9@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_196477_1	1165841.SULAR_05123	8.72e-110	323.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2YMIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_211790_1	1168034.FH5T_12085	3.34e-124	364.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,2FM8A@200643|Bacteroidia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_95814_1	1165841.SULAR_05918	7.7e-26	99.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2YP7A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetolactate synthase	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_95814_2	387093.SUN_1821	5.77e-42	147.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2YMCF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_227193_1	547559.Nmag_1960	1.26e-10	63.2	arCOG08099@1|root,arCOG08099@2157|Archaea,2XTZD@28890|Euryarchaeota,23S2K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165583_1	697282.Mettu_1033	2.62e-56	194.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XG3X@135618|Methylococcales	135618|Methylococcales	NU	General secretory system II, protein E, N-terminal	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_142225_2	765910.MARPU_11450	3.55e-13	65.9	COG0298@1|root,COG0298@2|Bacteria,1N9Z3@1224|Proteobacteria,1SCWQ@1236|Gammaproteobacteria,1WZ92@135613|Chromatiales	135613|Chromatiales	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_181018_1	1165841.SULAR_07910	4.42e-74	222.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2YP8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_181018_2	1165841.SULAR_07905	1.79e-78	234.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2YP73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_181018_3	1165841.SULAR_07900	0.000141	42.7	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2YMCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_165585_1	203122.Sde_3255	3.52e-38	136.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,464HJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_1304	GHMP_kinases_C,GHMP_kinases_N
k59_129266_1	998674.ATTE01000001_gene3683	1.09e-11	70.1	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria	2|Bacteria	P	zinc-transporting ATPase activity	-	-	-	ko:K03546,ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15.3,3.A.1.15.5	-	-	AAA_23,AAA_27,ABC_tran,SbcCD_C
k59_98262_1	1168034.FH5T_06140	5.09e-33	124.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,2FN33@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
k59_98262_2	1168034.FH5T_06135	6.05e-32	124.0	COG2956@1|root,COG2956@2|Bacteria,4PNWA@976|Bacteroidetes,2G0ZI@200643|Bacteroidia	976|Bacteroidetes	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k59_75081_1	743974.MBO_04354	1.19e-22	94.4	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,3NIUP@468|Moraxellaceae	1236|Gammaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103	IlvC,IlvN
k59_75081_2	754476.Q7A_2047	1.3e-74	227.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,460NY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_75081_3	2340.JV46_05750	1.95e-76	244.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1J523@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_98786_1	1049564.TevJSym_ak00780	8.75e-39	142.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_175986_1	1165841.SULAR_08332	2.56e-84	256.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,42ME8@68525|delta/epsilon subdivisions,2YN4W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_175986_2	1165841.SULAR_08327	1.25e-132	380.0	COG0388@1|root,COG0388@2|Bacteria,1PZZZ@1224|Proteobacteria,42REP@68525|delta/epsilon subdivisions,2YP77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_75643_1	1353529.M899_2051	4.06e-48	167.0	KOG0788@1|root,2Z9Q6@2|Bacteria,1R6QG@1224|Proteobacteria	1224|Proteobacteria	E	PFAM S-adenosylmethionine decarboxylase	speD	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	SAM_decarbox
k59_137307_1	1227266.HMPREF1551_00980	1.79e-14	77.4	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,1IG4W@117743|Flavobacteriia,1ET5Q@1016|Capnocytophaga	976|Bacteroidetes	S	Putative esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
k59_137307_2	742767.HMPREF9456_01246	6.66e-33	126.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,2FNXZ@200643|Bacteroidia,22XE3@171551|Porphyromonadaceae	976|Bacteroidetes	P	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
k59_222584_1	768671.ThimaDRAFT_3191	7.75e-30	123.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales	135613|Chromatiales	O	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Trans_reg_C
k59_191602_2	996306.SSUR61_1586	2.32e-28	115.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4ISAE@91061|Bacilli,1WS91@1307|Streptococcus suis	91061|Bacilli	C	FAD binding domain	frdC	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_145624_1	1499967.BAYZ01000019_gene6298	2.8e-72	227.0	COG0744@1|root,COG0744@2|Bacteria,2NRF9@2323|unclassified Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129,3.4.16.4	ko:K03814,ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k59_145624_2	870187.Thini_1055	8.52e-13	67.8	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,4632W@72273|Thiotrichales	72273|Thiotrichales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
k59_191603_1	185453.XP_006864391.1	3.61e-40	146.0	COG0451@1|root,KOG2774@2759|Eukaryota,39CSF@33154|Opisthokonta,3BHBY@33208|Metazoa,3CYGQ@33213|Bilateria,487Z0@7711|Chordata,48Z50@7742|Vertebrata,3J7Z7@40674|Mammalia,351VT@311790|Afrotheria	33208|Metazoa	GM	L-threonine 3-dehydrogenase	TDH	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008743,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.1.1.103	ko:K15789	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_106206_1	4555.Si020764m	5.57e-55	185.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta,3M2Z2@4447|Liliopsida,3ID3P@38820|Poales	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	nad7	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k59_29092_1	1541065.JRFE01000036_gene6504	3.2e-163	463.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1GDJV@1117|Cyanobacteria,3VN2P@52604|Pleurocapsales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_5924_1	99598.Cal7507_3690	3.29e-47	172.0	COG1357@1|root,COG1672@1|root,COG4249@1|root,COG1357@2|Bacteria,COG1672@2|Bacteria,COG4249@2|Bacteria,1G3JV@1117|Cyanobacteria,1HJ0H@1161|Nostocales	1117|Cyanobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pentapeptide,Peptidase_C14
k59_206991_1	1165841.SULAR_00205	9.5e-103	309.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2YMAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_13484_1	395493.BegalDRAFT_2505	8.03e-89	273.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_176009_1	1313421.JHBV01000139_gene1287	5.17e-70	223.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_83057_1	984262.SGRA_3790	2.16e-55	179.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,1IVMW@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_21236_1	323848.Nmul_A1251	8.94e-54	188.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,372T7@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Alpha-amylase domain	aglA	-	3.2.1.10,3.2.1.20	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
k59_114202_1	2340.JV46_02150	1.41e-78	239.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1J4HA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the SUA5 family	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_52249_1	65393.PCC7424_5741	3.31e-53	189.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,3KHHW@43988|Cyanothece	1117|Cyanobacteria	T	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA_3,PAS_4,Pkinase
k59_191608_1	395493.BegalDRAFT_3557	8.27e-24	97.1	COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,461AA@72273|Thiotrichales	72273|Thiotrichales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
k59_191608_2	582744.Msip34_2114	7.96e-27	109.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,2KKMV@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_5930_1	4155.Migut.D01524.1.p	6.44e-142	401.0	COG0852@1|root,KOG1713@2759|Eukaryota,37SXR@33090|Viridiplantae,3GGAU@35493|Streptophyta,44M86@71274|asterids	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	nad9	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3,1.6.99.3	ko:K03936	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_30kDa
k59_137312_1	765869.BDW_00880	1.28e-96	298.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2MST9@213481|Bdellovibrionales,2WJ0E@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_238017_1	1249627.D779_2144	4.18e-49	165.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria,1WWM7@135613|Chromatiales	135613|Chromatiales	C	reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_238017_2	2340.JV46_15500	4.79e-49	157.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1J6HU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	conserved protein involved in intracellular sulfur reduction	tusD	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
k59_207008_1	1165841.SULAR_09604	2.87e-130	380.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_207010_2	1046714.AMRX01000008_gene1060	3.48e-48	156.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,46851@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_160591_1	1095769.CAHF01000015_gene2765	3.61e-18	84.3	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,2VJE2@28216|Betaproteobacteria,472EE@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
k59_160591_2	1042375.AFPL01000018_gene309	1.04e-71	229.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,464DM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	SpoVR family	ycgB	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_214794_1	1168034.FH5T_08720	6.37e-47	171.0	COG3947@1|root,COG3947@2|Bacteria,4NFJU@976|Bacteroidetes,2FN4F@200643|Bacteroidia	976|Bacteroidetes	T	COG NOG26059 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_90833_1	404589.Anae109_0671	1.3e-51	178.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJ9@29|Myxococcales	28221|Deltaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_106226_1	41431.PCC8801_3952	9.15e-240	667.0	COG5659@1|root,COG5659@2|Bacteria,1G31J@1117|Cyanobacteria,3KJS7@43988|Cyanothece	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_199531_1	595460.RRSWK_07003	9.46e-51	183.0	COG0553@1|root,COG0553@2|Bacteria,2IXFX@203682|Planctomycetes	203682|Planctomycetes	L	COG0553 Superfamily II DNA RNA	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_152782_1	1165841.SULAR_05673	1.62e-99	300.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_176025_1	1278309.KB907101_gene522	2.18e-98	296.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XHEF@135619|Oceanospirillales	135619|Oceanospirillales	S	ATPase, AAA	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_60020_1	387093.SUN_0618	6.87e-77	241.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_60020_2	1165841.SULAR_00360	5.73e-185	525.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_106235_1	1095769.CAHF01000022_gene432	7.2e-85	283.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_29125_1	572477.Alvin_0766	4.75e-14	70.5	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1WW3H@135613|Chromatiales	135613|Chromatiales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_29125_2	1380355.JNIJ01000053_gene2150	3.38e-40	149.0	COG0179@1|root,COG1893@1|root,COG0179@2|Bacteria,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2TRJN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C,DUF2437,FAA_hydrolase
k59_176032_1	519989.ECTPHS_09403	8.19e-60	200.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k59_160596_2	1125863.JAFN01000001_gene1503	1.67e-13	70.9	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,42UIQ@68525|delta/epsilon subdivisions,2WQAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_207018_1	370438.PTH_1082	3.25e-64	215.0	COG0438@1|root,COG0438@2|Bacteria,1V5W1@1239|Firmicutes,24HV6@186801|Clostridia,263ZC@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k59_44583_1	1165841.SULAR_03517	9.32e-52	167.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,433JY@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_183952_1	2340.JV46_02640	9.77e-78	255.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1JB0I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_191622_2	502025.Hoch_1723	2.31e-11	68.6	COG4870@1|root,COG4870@2|Bacteria,1Q2ZQ@1224|Proteobacteria,438PA@68525|delta/epsilon subdivisions,2X3X1@28221|Deltaproteobacteria,2YXEN@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase C1 family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129820_1	1173027.Mic7113_5588	1.39e-88	275.0	COG2232@1|root,COG2232@2|Bacteria,1G4QF@1117|Cyanobacteria,1HEFH@1150|Oscillatoriales	1117|Cyanobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_137339_1	693979.Bache_1280	4.24e-22	102.0	COG3193@1|root,COG3193@2|Bacteria,4NGRH@976|Bacteroidetes,2FQRR@200643|Bacteroidia,4AQH9@815|Bacteroidaceae	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_98842_1	1174528.JH992892_gene6465	6.09e-23	96.7	COG4249@1|root,COG4249@2|Bacteria,1G0ZN@1117|Cyanobacteria	1117|Cyanobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
k59_44592_1	1249997.JHZW01000002_gene1638	4.33e-58	192.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia,2PGE7@252356|Maribacter	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_44592_2	313596.RB2501_09000	3.14e-10	59.3	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_106251_1	1121935.AQXX01000121_gene5591	3.02e-40	145.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XH9A@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_29138_1	2340.JV46_03510	9.3e-94	287.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J4EJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740	PK,PK_C
k59_207025_1	1461579.CCNK01000036_gene1574	6.19e-14	72.4	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1Y8E9@135625|Pasteurellales	135625|Pasteurellales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_102027_1	1232410.KI421413_gene499	3.59e-90	291.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43S4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	MutS domain I	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_78844_1	1165841.SULAR_06853	1.08e-30	116.0	COG0457@1|root,COG0457@2|Bacteria,1PDT9@1224|Proteobacteria,43AAF@68525|delta/epsilon subdivisions,2YQIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_2
k59_40269_2	1122604.JONR01000007_gene2852	4.28e-26	112.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1X43V@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thiol disulfide Interchange Protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_225834_1	1499967.BAYZ01000097_gene4351	2.37e-39	150.0	COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,PKD,VWA
k59_117553_1	765913.ThidrDRAFT_1888	1.01e-55	191.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_140811_1	1166130.H650_10830	2.38e-14	72.8	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria,3X067@547|Enterobacter	1236|Gammaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	ygfF	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_218178_1	32042.PstZobell_10364	2.76e-72	222.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1Z0RB@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	F	ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
k59_218178_2	56110.Oscil6304_0455	4.02e-58	200.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H72F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_102042_1	1187848.AJYQ01000003_gene410	7.56e-126	373.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_109801_1	1123354.AUDR01000004_gene1576	1.86e-19	94.4	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2VJWM@28216|Betaproteobacteria,1KT7Y@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Na+/Pi-cotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
k59_225858_2	357808.RoseRS_0707	0.000378	44.3	COG2345@1|root,COG2345@2|Bacteria,2G8V0@200795|Chloroflexi,375MI@32061|Chloroflexia	32061|Chloroflexia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_DeoR
k59_55669_1	1128421.JAGA01000002_gene1319	6.86e-12	71.2	COG1305@1|root,COG1305@2|Bacteria,2NQTS@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
k59_210260_1	944547.ABLL_2141	1.05e-47	155.0	COG0789@1|root,COG0789@2|Bacteria,1Q3QJ@1224|Proteobacteria,42XN5@68525|delta/epsilon subdivisions,2YR08@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_187149_1	1173028.ANKO01000008_gene2104	1.59e-73	258.0	COG0642@1|root,COG3829@1|root,COG4251@1|root,COG0642@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_2,PAS_3,PAS_9,PHY,Response_reg
k59_63354_1	1165841.SULAR_02738	1.86e-21	90.5	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2YN0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
k59_63354_2	1165841.SULAR_02743	3.99e-177	501.0	COG0479@1|root,COG0479@2|Bacteria,1QE4T@1224|Proteobacteria,42QE6@68525|delta/epsilon subdivisions,2YM7P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156169_1	1165841.SULAR_08217	1.15e-153	433.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2YMC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0566	DAP_epimerase
k59_156169_2	1165841.SULAR_08212	3.02e-39	135.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria	1224|Proteobacteria	NU	Sel1 domain protein repeat-containing protein	-	GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF3857,Sel1,Transglut_core
k59_179502_1	522306.CAP2UW1_4287	5.79e-12	66.6	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_179502_2	1122201.AUAZ01000019_gene1751	1.41e-31	117.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,4673X@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
k59_55675_1	765912.Thimo_0119	1.04e-167	491.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales	135613|Chromatiales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_16884_1	402777.KB235904_gene2889	1.21e-19	87.4	28HHG@1|root,2ZASK@2|Bacteria,1G3W2@1117|Cyanobacteria,1HAY9@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78898_1	1114959.SZMC14600_22920	1.07e-34	136.0	COG0331@1|root,COG2070@1|root,COG3321@1|root,COG0331@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,2GR80@201174|Actinobacteria,4DYFN@85010|Pseudonocardiales	201174|Actinobacteria	I	Dioxygenases related to 2-nitropropane dioxygenase	-	-	-	ko:K15329	-	-	-	-	ko00000,ko01008	-	-	-	Acyl_transf_1,NMO
k59_24690_1	1165841.SULAR_09024	1.88e-73	220.0	COG4802@1|root,COG4802@2|Bacteria,1QYD3@1224|Proteobacteria,42PN1@68525|delta/epsilon subdivisions,2YMYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B,Rhodanese
k59_24690_2	1165841.SULAR_09019	2.86e-62	192.0	COG0607@1|root,COG0607@2|Bacteria,1PX2U@1224|Proteobacteria,434B7@68525|delta/epsilon subdivisions,2YSA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_24690_3	1165841.SULAR_09014	1.16e-111	322.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,42SFN@68525|delta/epsilon subdivisions,2YSYM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0227
k59_24690_4	387093.SUN_0489	1.15e-180	509.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_171746_2	225849.swp_0845	2.23e-07	52.0	COG0705@1|root,COG3809@1|root,COG0705@2|Bacteria,COG3809@2|Bacteria,1MYFP@1224|Proteobacteria,1RSHC@1236|Gammaproteobacteria,2Q8ZU@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid,zf-TFIIB
k59_225868_1	1499967.BAYZ01000061_gene5969	5.39e-184	527.0	COG2114@1|root,COG2199@1|root,COG2114@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Guanylate_cyc,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
k59_32733_1	998674.ATTE01000001_gene1952	4.95e-73	259.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462CG@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM
k59_210281_1	698761.RTCIAT899_CH03985	9.78e-10	59.3	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VETM@28211|Alphaproteobacteria,4B9SG@82115|Rhizobiaceae	28211|Alphaproteobacteria	KT	helix_turn_helix, Lux Regulon	mctR	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_63383_1	1165841.SULAR_00285	1.27e-60	200.0	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,42VNT@68525|delta/epsilon subdivisions,2YRXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_117603_1	1168034.FH5T_02640	1.78e-160	466.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,2FP06@200643|Bacteroidia	976|Bacteroidetes	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
k59_32737_1	1168034.FH5T_07470	2.42e-135	405.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,2FPM1@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	bgaA	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_241232_1	765911.Thivi_2951	2.47e-80	246.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1WZ05@135613|Chromatiales	135613|Chromatiales	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_78921_1	686340.Metal_3355	3.64e-61	213.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XDSH@135618|Methylococcales	135618|Methylococcales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_117613_1	1123355.JHYO01000031_gene1575	3.51e-179	515.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TSTC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	Catalyzes the formation of catechol from phenol	-	-	1.14.13.7	ko:K03380	ko00623,ko00627,ko01120,map00623,map00627,map01120	-	R00815,R03566	RC00046,RC00236	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Phe_hydrox_dim
k59_218208_2	2340.JV46_14530	1.52e-81	265.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1J56P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_102058_2	1165841.SULAR_00420	3.26e-138	397.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_218211_1	395493.BegalDRAFT_1285	3.97e-107	335.0	COG1672@1|root,COG1672@2|Bacteria,1N54W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86652_1	1168034.FH5T_06760	2.98e-72	220.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,2FPZE@200643|Bacteroidia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_86652_2	873513.HMPREF6485_0113	2.23e-31	115.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,2FMES@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_241240_1	977880.RALTA_B1661	1.61e-96	295.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1K0R6@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	acoD	-	-	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	-	R00711	RC00047	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_71050_1	946077.W5A_08372	1.11e-83	259.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_71050_2	398720.MED217_01510	7.52e-13	68.2	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia,2XJRW@283735|Leeuwenhoekiella	976|Bacteroidetes	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_32742_1	1123400.KB904754_gene1035	1.68e-06	49.7	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,45ZXD@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1,Acetyltransf_7
k59_32742_2	81824.XP_001747449.1	8.38e-23	111.0	COG0642@1|root,KOG0519@2759|Eukaryota,391YN@33154|Opisthokonta	33154|Opisthokonta	T	detection of oxidative stress	CHK1	GO:0002831,GO:0002833,GO:0007162,GO:0008150,GO:0009272,GO:0009405,GO:0009607,GO:0009987,GO:0010033,GO:0010570,GO:0022407,GO:0022408,GO:0030100,GO:0030155,GO:0030447,GO:0032879,GO:0033993,GO:0036180,GO:0040007,GO:0040008,GO:0042221,GO:0042546,GO:0042710,GO:0043900,GO:0044010,GO:0044011,GO:0044085,GO:0044182,GO:0044419,GO:0044764,GO:0045806,GO:0045927,GO:0046677,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050765,GO:0050789,GO:0050794,GO:0050896,GO:0051040,GO:0051042,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051703,GO:0051704,GO:0051716,GO:0060627,GO:0065007,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071554,GO:0071840,GO:0071852,GO:0090033,GO:0090605,GO:0090609,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:1900190,GO:1900231,GO:1900428,GO:1900430,GO:1900443,GO:1900445,GO:1901700,GO:1901701	2.7.13.3	ko:K11231,ko:K19690,ko:K19692	ko02020,ko04011,ko04139,map02020,map04011,map04139	M00516	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
k59_40315_1	1123487.KB892865_gene1375	8.2e-48	163.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria,2KZJK@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
k59_241243_1	247634.GPB2148_498	2.5e-55	194.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,1S52W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
k59_55709_2	876044.IMCC3088_1761	1.14e-48	169.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_55716_1	85643.Tmz1t_2491	4.41e-84	260.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VM9J@28216|Betaproteobacteria,2KUHN@206389|Rhodocyclales	206389|Rhodocyclales	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_56011_2	1443113.LC20_03076	2.55e-26	102.0	COG3600@1|root,COG3600@2|Bacteria,1N78U@1224|Proteobacteria,1SFHM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
k59_25098_1	28532.XP_010526678.1	4.74e-74	258.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae,3GBWZ@35493|Streptophyta	35493|Streptophyta	L	cysteine-rich RLK (RECEPTOR-like protein kinase) 8	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve
k59_187538_1	670487.Ocepr_1720	1.46e-30	120.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_164339_1	983545.Glaag_3252	3.83e-08	56.2	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,1RQ5T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_66112_1	1168034.FH5T_13490	2.78e-82	260.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
k59_58250_1	1165841.SULAR_06913	2.52e-133	385.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2YMMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iIT341.HP0202	ACP_syn_III,ACP_syn_III_C
k59_58255_1	1121013.P873_10005	1.12e-84	268.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1X53V@135614|Xanthomonadales	135614|Xanthomonadales	T	gtp-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_174321_1	1165841.SULAR_08542	1.95e-72	220.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2YP6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_174321_2	1165841.SULAR_08537	2.17e-50	164.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2YMBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_19444_1	1123053.AUDG01000023_gene649	3.96e-25	104.0	COG2304@1|root,COG2304@2|Bacteria,1RGCN@1224|Proteobacteria,1S5GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
k59_89224_1	713587.THITH_13285	4.36e-12	66.2	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,1WXVR@135613|Chromatiales	135613|Chromatiales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_89224_2	1049564.TevJSym_bd00040	0.000183	42.7	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,1J515@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Flavocytochrome c sulphide dehydrogenase, flavin-binding	fccB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_128171_1	4155.Migut.D01329.1.p	1.44e-79	236.0	COG0197@1|root,KOG3422@2759|Eukaryota,37UTS@33090|Viridiplantae,3GIPW@35493|Streptophyta,44T4M@71274|asterids	35493|Streptophyta	J	Belongs to the universal ribosomal protein uL16 family	rpl16	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_128171_2	3880.AES67158	3.43e-19	82.8	COG0093@1|root,COG0100@1|root,KOG0408@2759|Eukaryota,KOG0901@2759|Eukaryota,37UWF@33090|Viridiplantae,3GIPC@35493|Streptophyta	35493|Streptophyta	J	Belongs to the universal ribosomal protein uL14 family	rpl14	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0008150,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0015934,GO:0019843,GO:0031974,GO:0031976,GO:0031984,GO:0032991,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0070013,GO:0070180,GO:0097159,GO:0098798,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_42909_1	395493.BegalDRAFT_3277	7.96e-97	300.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CZB,EAL,GAF_2,GGDEF,NMT1,PAS,PAS_3,PAS_9,Phosphonate-bd,SBP_bac_3
k59_128176_1	690850.Desaf_1120	3.8e-14	71.2	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WJ0I@28221|Deltaproteobacteria,2MG34@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_128176_2	886379.AEWI01000007_gene837	2.96e-58	190.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,2FND2@200643|Bacteroidia,3XJF4@558415|Marinilabiliaceae	976|Bacteroidetes	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_182337_1	1121033.AUCF01000039_gene437	4.45e-18	80.9	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2TUH8@28211|Alphaproteobacteria,2JXUE@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_182337_2	395493.BegalDRAFT_2310	1.5e-12	64.3	COG2033@1|root,COG2033@2|Bacteria,1QVWP@1224|Proteobacteria,1SE90@1236|Gammaproteobacteria,463TZ@72273|Thiotrichales	72273|Thiotrichales	C	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_151083_1	1168034.FH5T_17845	1.67e-70	231.0	COG4251@1|root,COG4251@2|Bacteria,4PMMC@976|Bacteroidetes	976|Bacteroidetes	T	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM,PAS_9
k59_58269_1	1168034.FH5T_15045	5.49e-114	340.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,2FKYJ@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_205363_1	396588.Tgr7_0774	1.04e-112	334.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales	135613|Chromatiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_58271_1	1165841.SULAR_08642	1.99e-116	352.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2YNRH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_135716_1	1247024.JRLH01000001_gene1005	7.95e-43	161.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_35338_1	1517416.IDAT_04000	7.31e-83	258.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,2QFRZ@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Peptidase dimerisation domain	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_166930_1	1254432.SCE1572_41675	8.36e-72	234.0	COG4650@1|root,COG4650@2|Bacteria,1MX6U@1224|Proteobacteria,42NHB@68525|delta/epsilon subdivisions,2WKUB@28221|Deltaproteobacteria,2YTU9@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-54 dependent transcriptional regulator	rtcR	-	-	ko:K14414	-	-	-	-	ko00000,ko03000	-	-	-	RtcR,Sigma54_activat
k59_143665_1	1165841.SULAR_08127	7.11e-34	128.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_35341_1	1120968.AUBX01000010_gene1305	5.34e-14	76.3	COG2227@1|root,COG2227@2|Bacteria,4NFHE@976|Bacteroidetes,47JIB@768503|Cytophagia	976|Bacteroidetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_244002_1	1026882.MAMP_01424	3.32e-85	260.0	COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,1RSI6@1236|Gammaproteobacteria,463PE@72273|Thiotrichales	72273|Thiotrichales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_19455_1	2340.JV46_28110	1.52e-92	293.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1J4ZW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_120387_1	387093.SUN_0366	3.16e-130	395.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2YNPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_135722_1	550540.Fbal_2191	1.54e-16	79.3	28I8B@1|root,2Z8B5@2|Bacteria,1R013@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Cytochrome_cB
k59_112605_1	1165841.SULAR_01395	5.03e-141	404.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2YMPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_104670_1	763034.HMPREF9446_00580	2.83e-62	204.0	COG2730@1|root,COG2730@2|Bacteria,4NH83@976|Bacteroidetes,2FNQD@200643|Bacteroidia,4ANG7@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
k59_174344_1	243365.CV_2802	1.23e-33	133.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KQ86@206351|Neisseriales	206351|Neisseriales	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_58289_1	1168034.FH5T_04385	3.94e-102	314.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia	976|Bacteroidetes	O	ATPase histidine kinase DNA gyrase B HSP90 domain protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_50552_2	259536.Psyc_0246	2.52e-36	124.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,3NNIM@468|Moraxellaceae	1236|Gammaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_9
k59_166936_1	90675.XP_010424030.1	2.98e-09	58.5	KOG1075@1|root,KOG1075@2759|Eukaryota,37T71@33090|Viridiplantae,3GHK2@35493|Streptophyta,3I05T@3699|Brassicales	35493|Streptophyta	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	C2,DUF4283,RVT_1,RVT_3,zf-RVT
k59_58291_1	1168034.FH5T_04265	1.42e-30	114.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,2FMI3@200643|Bacteroidia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_58291_2	1168034.FH5T_04270	3.92e-51	171.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,2FXM7@200643|Bacteroidia	976|Bacteroidetes	F	AIR synthase related protein, C-terminal domain	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
k59_236443_1	1165841.SULAR_06398	4.78e-42	145.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_236443_2	1165841.SULAR_06403	2.01e-25	95.9	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_35346_1	1165841.SULAR_02473	1.91e-91	276.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2YMGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_4488_1	926561.KB900618_gene449	7.39e-24	100.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_4488_2	326297.Sama_1355	5.12e-24	100.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,2QB5K@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_120396_1	1168034.FH5T_04010	3.27e-93	276.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,2FNA8@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_120396_2	1168034.FH5T_04005	5.52e-05	44.3	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_182362_1	1165841.SULAR_00190	2.76e-112	330.0	COG1565@1|root,COG1565@2|Bacteria,1QNDB@1224|Proteobacteria,42MQ8@68525|delta/epsilon subdivisions,2YNBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_151112_1	2340.JV46_04100	5.31e-25	101.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1J6NP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
k59_50558_1	1168034.FH5T_01680	4.58e-97	294.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,2FREU@200643|Bacteroidia	976|Bacteroidetes	H	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_182363_1	2340.JV46_22770	6.16e-99	301.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1J5GF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG1530 Ribonucleases G and E	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_182364_2	485913.Krac_2258	4.71e-51	166.0	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1
k59_205407_2	1238450.VIBNISOn1_30078	4.33e-31	118.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1MWTF@1224|Proteobacteria,1RQMF@1236|Gammaproteobacteria,1Y2US@135623|Vibrionales	135623|Vibrionales	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
k59_143688_1	595536.ADVE02000001_gene1920	1.2e-77	248.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,36Y58@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	rhbB	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_166954_1	1165841.SULAR_05318	1.53e-106	313.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2YMG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_50567_1	1168034.FH5T_17445	9.76e-47	156.0	2C0BR@1|root,302EW@2|Bacteria,4P9SR@976|Bacteroidetes,2FQUQ@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
k59_35358_1	349965.yinte0001_14790	7.54e-62	205.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria,41ETQ@629|Yersinia	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_174354_1	96561.Dole_0453	1.06e-111	328.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MIME@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k59_151133_1	498211.CJA_1630	1.02e-34	129.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1FG2A@10|Cellvibrio	1236|Gammaproteobacteria	F	AIR synthase related protein, N-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2340	AIRS,AIRS_C
k59_151133_2	1121943.KB899993_gene59	7.13e-17	78.6	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1XJ71@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_58307_1	278957.ABEA03000135_gene1756	5.15e-27	108.0	COG3328@1|root,COG3328@2|Bacteria,46Y7N@74201|Verrucomicrobia,3K92J@414999|Opitutae	414999|Opitutae	L	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_58307_2	1396418.BATQ01000199_gene3625	1.76e-08	54.3	COG3328@1|root,COG3328@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_143704_1	688270.Celal_0455	0.000272	48.9	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,1F8T1@104264|Cellulophaga	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_205412_1	395493.BegalDRAFT_0733	1.05e-42	162.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
k59_11996_1	216596.RL3505	5.81e-81	250.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,4B7N6@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k59_136165_1	1165841.SULAR_04607	6.21e-146	417.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,42MX3@68525|delta/epsilon subdivisions,2YR64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2951 Membrane-bound lytic murein transglycosylase B	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_120848_1	1192868.CAIU01000031_gene3964	1.69e-07	53.1	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2TRHI@28211|Alphaproteobacteria,43JAX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_82013_1	870187.Thini_2789	5.36e-20	89.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_167356_1	1123518.ARWI01000001_gene2416	8e-12	65.9	COG1595@1|root,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,1RU98@1236|Gammaproteobacteria,4632H@72273|Thiotrichales	72273|Thiotrichales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_151512_1	1168034.FH5T_11730	2.41e-86	264.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,2FNVM@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_97562_1	880071.Fleli_2004	7.8e-35	138.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_190361_1	1549858.MC45_00055	1.07e-91	293.0	COG0323@1|root,COG0323@2|Bacteria,1R57G@1224|Proteobacteria,2UEXM@28211|Alphaproteobacteria,2KC76@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA mismatch repair	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_66549_2	762903.Pedsa_0222	2.99e-30	119.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
k59_12341_1	519989.ECTPHS_07097	4.88e-80	253.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_221406_1	768671.ThimaDRAFT_1855	5.62e-35	124.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1WY27@135613|Chromatiales	135613|Chromatiales	I	PFAM CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_221406_2	1173020.Cha6605_5761	1.33e-17	76.6	COG0271@1|root,COG0271@2|Bacteria,1G7V3@1117|Cyanobacteria	1117|Cyanobacteria	T	Belongs to the BolA IbaG family	colA	-	-	-	-	-	-	-	-	-	-	-	BolA
k59_50982_1	1408473.JHXO01000001_gene2271	3.22e-87	264.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,2FN8Z@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_77048_1	205914.HS_0153	1.18e-05	51.6	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y909@135625|Pasteurellales	135625|Pasteurellales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_92199_1	765913.ThidrDRAFT_1082	2.82e-82	256.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1WWZ0@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_77049_1	526218.Sterm_2734	5.89e-06	52.4	COG0795@1|root,COG0795@2|Bacteria,378KF@32066|Fusobacteria	32066|Fusobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_223973_2	870187.Thini_1443	6.05e-09	57.8	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,45ZQ9@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_14802_1	411477.PARMER_00128	1.14e-05	58.2	COG0823@1|root,COG0823@2|Bacteria,4NGH4@976|Bacteroidetes,2FN8G@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_61406_1	1198232.CYCME_0851	1.34e-18	80.9	COG4659@1|root,COG4659@2|Bacteria,1RFGW@1224|Proteobacteria,1S603@1236|Gammaproteobacteria,462YS@72273|Thiotrichales	72273|Thiotrichales	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
k59_61406_2	443598.AUFA01000020_gene3124	3.95e-40	148.0	COG1477@1|root,COG1477@2|Bacteria,1RIPS@1224|Proteobacteria,2V46K@28211|Alphaproteobacteria,3JT81@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_69193_1	1289135.A966_09511	6.19e-76	250.0	COG0525@1|root,COG0525@2|Bacteria,2J659@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_84484_1	1123278.KB893444_gene1727	2.63e-32	125.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes,47KH7@768503|Cytophagia	976|Bacteroidetes	S	Peptidase U62 modulator of DNA gyrase	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_45926_1	1392489.JPOL01000002_gene2686	4.97e-21	93.2	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia,2XK0Y@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Heavy-metal-associated domain	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_45926_2	761193.Runsl_5933	8.9e-16	73.6	COG0845@1|root,COG0845@2|Bacteria,4NT55@976|Bacteroidetes,47Q0W@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
k59_115577_1	449447.MAE_59290	6.02e-120	348.0	2DM7C@1|root,3214Q@2|Bacteria,1GQS7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_231363_1	2340.JV46_25840	1.96e-150	446.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1J526@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_154186_1	1249997.JHZW01000002_gene186	2.51e-100	310.0	COG1629@1|root,COG4771@2|Bacteria,4PKB3@976|Bacteroidetes,1IJ66@117743|Flavobacteriia,2PG7Q@252356|Maribacter	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
k59_208411_1	1165841.SULAR_01758	4.44e-158	462.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_200883_1	4081.Solyc09g015860.1.1	3.59e-60	188.0	COG0197@1|root,KOG3422@2759|Eukaryota,37TB9@33090|Viridiplantae,3GGF9@35493|Streptophyta	35493|Streptophyta	J	RIBOSOMAL protein	-	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_138653_1	143224.JQMD01000002_gene2643	7.37e-46	162.0	COG0860@1|root,COG0860@2|Bacteria,4NHZA@976|Bacteroidetes,1HXWY@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
k59_208412_1	1122194.AUHU01000005_gene940	5.52e-27	103.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,467AM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
k59_208412_2	467661.RKLH11_3959	1.52e-46	159.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TUVG@28211|Alphaproteobacteria,3ZI3Q@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_69203_1	485913.Krac_9981	1.75e-98	305.0	COG1012@1|root,COG1012@2|Bacteria,2G83P@200795|Chloroflexi	200795|Chloroflexi	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_45932_1	933262.AXAM01000084_gene1047	4.94e-76	242.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MISA@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_170071_1	2340.JV46_05360	3.47e-99	295.0	COG2010@1|root,COG2010@2|Bacteria,1PDUJ@1224|Proteobacteria,1SUEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
k59_30614_1	1121875.KB907546_gene2275	2.86e-76	232.0	COG1595@1|root,COG1595@2|Bacteria,4NHNI@976|Bacteroidetes,1HY4K@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_247016_1	744980.TRICHSKD4_1273	3.64e-08	61.6	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidylprolyl isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
k59_138657_1	1499967.BAYZ01000149_gene6776	6.61e-12	66.2	COG4974@1|root,COG4974@2|Bacteria,2NRIN@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_138657_2	479433.Caci_1315	8.72e-33	122.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria	201174|Actinobacteria	J	Phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k59_123605_1	177437.HRM2_23670	1.18e-22	104.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,42N9P@68525|delta/epsilon subdivisions,2WJ0G@28221|Deltaproteobacteria,2MJ0M@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_138660_1	1168034.FH5T_20930	3.31e-93	291.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_30620_1	1131814.JAFO01000001_gene3832	6.42e-14	76.3	COG1802@1|root,COG1802@2|Bacteria,1MXNF@1224|Proteobacteria,2U1PK@28211|Alphaproteobacteria,3EY4W@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_123607_1	998674.ATTE01000001_gene1311	1.89e-62	199.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	phbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
k59_77087_1	1485544.JQKP01000015_gene2090	9.06e-59	197.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2WD6M@28216|Betaproteobacteria,44WJD@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_200909_1	1165841.SULAR_00425	1.29e-131	389.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_22678_1	1165841.SULAR_10364	1.3e-116	369.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_208429_1	697282.Mettu_1144	1.83e-94	292.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,1S6J3@1236|Gammaproteobacteria,1XFRI@135618|Methylococcales	135618|Methylococcales	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_208432_1	3880.AES58577	7.62e-84	273.0	COG0056@1|root,COG0356@1|root,COG1622@1|root,KOG1353@2759|Eukaryota,KOG4665@2759|Eukaryota,KOG4767@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta,4JSJY@91835|fabids	35493|Streptophyta	C	ATP synthase	atp1	-	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,COX2_TM
k59_138679_2	1331060.RLDS_14005	9.07e-05	45.1	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,2TRSJ@28211|Alphaproteobacteria,2K00G@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_53602_1	316274.Haur_1682	3.17e-31	128.0	COG5267@1|root,COG5267@2|Bacteria,2G7Q0@200795|Chloroflexi,376N0@32061|Chloroflexia	2|Bacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_162011_1	1121374.KB891575_gene1092	4.26e-08	58.2	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_162011_2	1085623.GNIT_3657	2.75e-18	82.8	COG3637@1|root,COG3637@2|Bacteria,1QXK4@1224|Proteobacteria,1T3DI@1236|Gammaproteobacteria,46752@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,SH3_3,SH3_4
k59_162013_1	483219.LILAB_31270	9.56e-08	55.1	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
k59_69238_1	870187.Thini_3578	4.54e-85	253.0	COG3012@1|root,COG3012@2|Bacteria,1N4HZ@1224|Proteobacteria,1SFB1@1236|Gammaproteobacteria,462H1@72273|Thiotrichales	72273|Thiotrichales	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154204_1	1524467.IV04_18485	4.9e-170	487.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,40000@613|Serratia	1236|Gammaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUTI89_1310.UTI89_C0772,iZ_1308.Z0993	Aminotran_3
k59_162015_1	414684.RC1_2539	1.8e-15	74.7	COG0842@1|root,COG0842@2|Bacteria,1MUF4@1224|Proteobacteria,2TRTS@28211|Alphaproteobacteria,2JPRJ@204441|Rhodospirillales	204441|Rhodospirillales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_162015_2	1123368.AUIS01000009_gene2454	1.38e-51	170.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_53611_1	582899.Hden_1429	3.33e-86	268.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	oxidoreductase	-	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
k59_77095_1	998088.B565_1001	2.31e-16	78.6	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1Y3VQ@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_177310_1	1249975.JQLP01000001_gene3504	8.49e-08	51.2	COG2963@1|root,COG2963@2|Bacteria,4NRTR@976|Bacteroidetes,1II7C@117743|Flavobacteriia	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_177310_2	616991.JPOO01000003_gene337	7.11e-107	318.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,23I5E@178469|Arenibacter	976|Bacteroidetes	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_177311_1	313596.RB2501_01945	8.91e-48	161.0	COG2258@1|root,COG2258@2|Bacteria,4NGQN@976|Bacteroidetes,1I049@117743|Flavobacteriia	976|Bacteroidetes	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_84511_1	1348583.ATLH01000029_gene1334	1.06e-124	363.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia,1F8GP@104264|Cellulophaga	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, transmembrane domain	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
k59_131216_1	1232410.KI421424_gene1696	1.26e-75	246.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,43TR4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_224363_1	1242864.D187_001958	2.27e-15	82.8	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_46334_1	1226322.HMPREF1545_04309	1.42e-36	141.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,2N6XH@216572|Oscillospiraceae	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_224365_1	1168034.FH5T_20290	2.13e-109	328.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia	976|Bacteroidetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_177752_1	395493.BegalDRAFT_1870	7.13e-53	185.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,45ZTT@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
k59_216493_1	525373.HMPREF0766_10902	8.01e-80	254.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_54045_1	313603.FB2170_11511	2.12e-41	146.0	COG2897@1|root,COG2897@2|Bacteria,4NJGQ@976|Bacteroidetes,1HYM5@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_61871_1	1392488.JHZY01000002_gene183	4.43e-36	134.0	COG0545@1|root,COG0545@2|Bacteria,4NJPK@976|Bacteroidetes,1HY2J@117743|Flavobacteriia,2XIT3@283735|Leeuwenhoekiella	976|Bacteroidetes	O	peptidyl-prolyl	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
k59_177758_1	1122619.KB892341_gene785	4.94e-77	252.0	COG3012@1|root,COG3012@2|Bacteria,1R5E5@1224|Proteobacteria,2VZMD@28216|Betaproteobacteria,3T744@506|Alcaligenaceae	28216|Betaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,SEC-C
k59_61876_1	768671.ThimaDRAFT_4484	6.62e-119	353.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1Q7PK@1224|Proteobacteria,1RSF0@1236|Gammaproteobacteria,1WWA3@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
k59_154563_1	357804.Ping_2328	2.41e-52	175.0	COG0615@1|root,COG0615@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_154563_2	357804.Ping_2327	1.01e-64	211.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,2QJ72@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
k59_23136_1	485915.Dret_2298	1.68e-186	535.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Q0C@68525|delta/epsilon subdivisions,2WIIZ@28221|Deltaproteobacteria,2MDPJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
k59_231750_1	395493.BegalDRAFT_2346	6.91e-65	224.0	COG0784@1|root,COG4251@1|root,COG0784@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
k59_177767_1	933262.AXAM01000003_gene2805	1.71e-43	150.0	COG0727@1|root,COG0727@2|Bacteria,1RIJV@1224|Proteobacteria,42U8U@68525|delta/epsilon subdivisions,2WPB4@28221|Deltaproteobacteria,2MKIE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k59_23140_1	1165841.SULAR_04407	3.73e-50	162.0	COG0319@1|root,COG0319@2|Bacteria,1Q9G0@1224|Proteobacteria,42SJD@68525|delta/epsilon subdivisions,2YPJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_23140_2	1165841.SULAR_04412	5.36e-41	143.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42Q58@68525|delta/epsilon subdivisions,2YNDQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_239823_1	1173022.Cri9333_4331	1.71e-53	201.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,Pkinase,Response_reg
k59_195418_1	944547.ABLL_1205	2.21e-59	190.0	COG1309@1|root,COG1309@2|Bacteria,1RDIP@1224|Proteobacteria,42XZ0@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
k59_195418_2	1387312.BAUS01000002_gene918	3.15e-20	87.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VT80@28216|Betaproteobacteria,2KMQP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k59_71470_2	926562.Oweho_1655	1.24e-61	211.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia,2PA72@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_2057_1	1198452.Jab_1c09820	3.5e-52	179.0	2BKCR@1|root,32ETA@2|Bacteria,1RJ21@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_195422_1	1123234.AUKI01000017_gene2706	7.96e-129	396.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_148838_1	1121405.dsmv_3623	7.09e-18	83.6	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42RYT@68525|delta/epsilon subdivisions,2WPIU@28221|Deltaproteobacteria,2MKB6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_148838_2	765912.Thimo_1294	3.23e-13	68.6	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1WW58@135613|Chromatiales	135613|Chromatiales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_241728_1	1249627.D779_4054	6.09e-72	235.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alkaline phosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_164466_1	768671.ThimaDRAFT_0078	2.52e-29	113.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WWR6@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator, LysR	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_164466_2	316055.RPE_2686	2.34e-09	57.8	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2TSJV@28211|Alphaproteobacteria,3JU4U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbM	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_226261_1	388413.ALPR1_21088	1.55e-08	63.2	COG1361@1|root,COG3210@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11
k59_87030_1	2340.JV46_15380	3.74e-58	190.0	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	dsrS	-	-	-	-	-	-	-	-	-	-	-	-
k59_87030_2	2340.JV46_15390	1.69e-20	84.0	COG0316@1|root,COG0316@2|Bacteria,1RKPC@1224|Proteobacteria,1SB76@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the HesB IscA family	dsrR	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_148847_1	313596.RB2501_10772	7.31e-43	157.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_40753_1	1417296.U879_08095	3.46e-66	209.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2U4AQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_234267_1	1121405.dsmv_3797	8.95e-114	338.0	COG4467@1|root,COG4467@2|Bacteria,1QW8C@1224|Proteobacteria	1224|Proteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_48441_1	1408428.JNJP01000007_gene1889	7.03e-94	293.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2M885@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_187647_1	1002367.HMPREF0673_02516	2.29e-09	53.1	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,2FTSK@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
k59_187647_2	1168034.FH5T_19690	1.43e-36	129.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,2FQJ0@200643|Bacteroidia	976|Bacteroidetes	S	ATP cob(I)alamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
k59_241743_1	1168034.FH5T_16735	1.43e-95	282.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG19144 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_241743_2	1168034.FH5T_16740	1.11e-14	73.6	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,2FNT1@200643|Bacteroidia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
k59_79418_1	228410.NE0619	4.94e-42	148.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,372KR@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_234278_1	1239415.CM001837_gene1301	7.4e-77	241.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1HWJX@117743|Flavobacteriia,37EYW@326319|Dokdonia	976|Bacteroidetes	H	Elongator protein 3, MiaB family, Radical SAM	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_195448_1	1085623.GNIT_2117	2.04e-43	160.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,46415@72275|Alteromonadaceae	1236|Gammaproteobacteria	OU	COG0616 Periplasmic serine proteases (ClpP class)	sppA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_234280_1	484770.UFO1_2836	2.76e-29	114.0	COG1850@1|root,COG1850@2|Bacteria,1TSZQ@1239|Firmicutes,4H3SI@909932|Negativicutes	909932|Negativicutes	G	ribulose- bisphosphate carboxylase large chain	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large
k59_234280_3	765911.Thivi_0211	3.5e-24	96.3	COG0639@1|root,COG0639@2|Bacteria,1RF21@1224|Proteobacteria,1S4CI@1236|Gammaproteobacteria,1WYEH@135613|Chromatiales	135613|Chromatiales	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
k59_33269_1	929558.SMGD1_1625	1.62e-95	291.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,OMP_b-brl,OmpA,Surface_Ag_2
k59_141279_1	765913.ThidrDRAFT_2074	2.55e-53	175.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,1WX85@135613|Chromatiales	135613|Chromatiales	P	PFAM carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_148870_1	2340.JV46_22290	4.08e-45	154.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1J4DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Mg2 and Co2 transporter CorC	corC	GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_148870_2	945543.VIBR0546_09694	4.23e-34	133.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XSXY@135623|Vibrionales	135623|Vibrionales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_9877_1	98439.AJLL01000096_gene4135	6.19e-39	157.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1G4CE@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_241755_1	425104.Ssed_2865	2.59e-14	77.8	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QACP@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_218654_1	2340.JV46_04670	2.18e-60	194.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1J6D4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_218654_2	2340.JV46_04680	4.87e-39	130.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,1SCEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Thioredoxin_3
k59_187660_1	36875.HQ29_05350	6.9e-19	86.7	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia,22W33@171551|Porphyromonadaceae	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1
k59_79435_1	1046714.AMRX01000006_gene3063	7.28e-12	65.9	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,464UE@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_79435_2	348780.NP_3196A	4.71e-09	60.1	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,23TI6@183963|Halobacteria	183963|Halobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_118128_1	360910.BAV0872	1.66e-30	112.0	COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,2VTSP@28216|Betaproteobacteria,3T942@506|Alcaligenaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_95204_1	1288826.MSNKSG1_11478	1.14e-28	110.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,1RPWN@1236|Gammaproteobacteria,467HB@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Lysine exporter protein LysE YggA	rhtB	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	ko:K05834	-	-	-	-	ko00000,ko02000	2.A.76.1.1	-	iECIAI39_1322.ECIAI39_3185	LysE
k59_56437_1	65393.PCC7424_4442	3.82e-10	65.9	COG0642@1|root,COG2202@1|root,COG2461@1|root,COG4251@1|root,COG5000@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,1G0A1@1117|Cyanobacteria,3KJ8K@43988|Cyanothece	1117|Cyanobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9
k59_156989_1	1392502.JNIO01000002_gene407	2.24e-46	155.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k59_156989_2	701176.VIBRN418_00891	1.67e-75	237.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,1S2SE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
k59_156990_1	631362.Thi970DRAFT_04731	4.13e-93	298.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,1WWG2@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_95219_1	313596.RB2501_13224	5.05e-96	289.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_10216_1	671143.DAMO_2488	2.02e-33	129.0	COG1459@1|root,COG1459@2|Bacteria,2NP2J@2323|unclassified Bacteria	2|Bacteria	U	Type II secretion system (T2SS), protein F	xpsF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_56449_1	243233.MCA1276	2.24e-67	216.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1XE0C@135618|Methylococcales	135618|Methylococcales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_195821_1	43989.cce_1138	1.21e-36	144.0	COG0745@1|root,COG0834@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0834@2|Bacteria,COG4251@2|Bacteria,1GHFQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,dCache_1
k59_164858_1	15368.BRADI1G44060.1	3.07e-50	182.0	COG0191@1|root,COG2084@1|root,KOG0409@2759|Eukaryota,KOG4153@2759|Eukaryota,37I1B@33090|Viridiplantae,3GEGM@35493|Streptophyta,3KQKR@4447|Liliopsida,3I5RC@38820|Poales	35493|Streptophyta	G	Ketose-bisphosphate aldolase class-II family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537,F_bP_aldolase,NAD_binding_11,NAD_binding_2
k59_56460_1	247490.KSU1_C0452	1.5e-27	115.0	COG1629@1|root,COG4771@2|Bacteria,2J2B7@203682|Planctomycetes	203682|Planctomycetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_188050_1	83406.HDN1F_18480	3.73e-32	115.0	COG0739@1|root,COG0739@2|Bacteria,1R9V0@1224|Proteobacteria,1RZIG@1236|Gammaproteobacteria,1JA8G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
k59_164864_1	118161.KB235922_gene396	1.33e-99	298.0	COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_2472_1	1168034.FH5T_04645	1.68e-68	224.0	COG1538@1|root,COG1538@2|Bacteria,4NFTV@976|Bacteroidetes,2FXIP@200643|Bacteroidia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_195835_1	929558.SMGD1_1460	2.58e-139	400.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42QG8@68525|delta/epsilon subdivisions,2YNS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_2475_1	1123242.JH636436_gene130	1.22e-35	137.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_118509_1	1168034.FH5T_17590	4.46e-131	390.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,2G2QE@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
k59_129341_1	1165841.SULAR_09979	6.69e-101	306.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,430CZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_191210_1	1165841.SULAR_00160	1.25e-58	191.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_229583_1	1120951.AUBG01000013_gene2566	4.55e-78	248.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1HYXT@117743|Flavobacteriia	976|Bacteroidetes	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_5528_1	713586.KB900536_gene2810	1.63e-15	76.3	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_5528_2	1123393.KB891326_gene13	2.18e-49	161.0	COG1416@1|root,COG1416@2|Bacteria,1NAV2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_113709_1	1121937.AUHJ01000007_gene1934	4.56e-14	70.5	2DICG@1|root,302RI@2|Bacteria,1PVSB@1224|Proteobacteria,1STCY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5529_1	1123054.KB907728_gene3025	5.91e-84	256.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1WXUX@135613|Chromatiales	135613|Chromatiales	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_222124_1	1144305.PMI02_03368	3.1e-72	239.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,2K2A2@204457|Sphingomonadales	204457|Sphingomonadales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_136867_1	1442598.JABW01000021_gene2067	1.97e-34	128.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2YNEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_168188_1	1242864.D187_010261	3.19e-12	71.6	COG0784@1|root,COG4251@1|root,COG0784@2|Bacteria,COG4251@2|Bacteria,1R7PN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,RsbRD_N
k59_90399_1	227377.CBU_1509	7.77e-77	248.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1JD0N@118969|Legionellales	118969|Legionellales	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k59_90399_2	523791.Kkor_1674	8.21e-40	140.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1XJZI@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_20718_2	1121920.AUAU01000004_gene869	1.82e-26	103.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k59_90401_1	313628.LNTAR_03889	3.81e-30	114.0	COG4181@1|root,COG4181@2|Bacteria	2|Bacteria	Q	ATPase activity	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_90403_1	261292.Nit79A3_3129	5.73e-30	123.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,2WGY0@28216|Betaproteobacteria,374ME@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k59_160140_1	1168034.FH5T_18950	3.5e-16	77.8	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_160140_2	1168034.FH5T_18945	3.38e-62	204.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,2FMC4@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_44153_1	1168034.FH5T_10890	4.79e-08	62.4	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_199127_1	313596.RB2501_12462	3.73e-120	357.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,1HYJT@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_206478_1	1165841.SULAR_05418	6.87e-120	353.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1Q55C@1224|Proteobacteria,42RCA@68525|delta/epsilon subdivisions,2YND3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	PPR
k59_28653_1	1071679.BG57_11000	1.31e-54	196.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K04780	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,Thioesterase
k59_145166_1	1117318.PRUB_20274	7.63e-40	151.0	COG0790@1|root,COG1672@1|root,COG0790@2|Bacteria,COG1672@2|Bacteria,1R5T1@1224|Proteobacteria,1S1D6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_8
k59_237616_1	925775.XVE_2574	1.69e-10	63.5	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1X62Z@135614|Xanthomonadales	135614|Xanthomonadales	O	Thiol disulfide Interchange Protein	-	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
k59_237616_2	945550.VISI1226_18626	0.000196	43.5	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XVQC@135623|Vibrionales	135623|Vibrionales	C	COG2863 Cytochrome c553	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_121738_1	3649.evm.model.supercontig_263.4	1.59e-166	478.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,3GEEJ@35493|Streptophyta,3HWMV@3699|Brassicales	35493|Streptophyta	C	Cytochrome C and Quinol oxidase polypeptide I	cox1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k59_113749_1	90813.JQMT01000001_gene1347	1.78e-89	271.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,4600W@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_13090_1	880073.Calab_3330	2.8e-60	201.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,2NS2I@2323|unclassified Bacteria	2|Bacteria	O	Pyridine nucleotide-disulphide oxidoreductase	trxB_2	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Pyr_redox_3
k59_222143_1	1165841.SULAR_05713	2.55e-106	320.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_237621_1	323261.Noc_0816	9.07e-39	146.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_98357_2	314275.MADE_1014590	1.27e-58	191.0	2CABR@1|root,32TG1@2|Bacteria,1N041@1224|Proteobacteria,1S4Q8@1236|Gammaproteobacteria,46BGC@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98357_4	1219031.BBJR01000065_gene1151	1.63e-19	85.1	2CIBZ@1|root,2ZH0V@2|Bacteria,1PBAQ@1224|Proteobacteria,2W5YZ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98357_5	314275.MADE_1014600	1.61e-70	226.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
k59_145193_1	1341181.FLJC2902T_09140	6.47e-14	66.6	COG3360@1|root,COG3360@2|Bacteria,4NURJ@976|Bacteroidetes,1I534@117743|Flavobacteriia,2NXJZ@237|Flavobacterium	976|Bacteroidetes	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_229622_2	1165841.SULAR_05258	2.1e-65	200.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2YPEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_229622_3	1165841.SULAR_05253	1e-07	52.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2YNUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_28673_1	765912.Thimo_2121	5.06e-20	85.5	COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,1S2EF@1236|Gammaproteobacteria,1WY2H@135613|Chromatiales	135613|Chromatiales	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_214668_1	4530.OS02T0192200-01	2.58e-09	62.0	28ITG@1|root,2QR4U@2759|Eukaryota,37P39@33090|Viridiplantae,3GE2D@35493|Streptophyta,3KV2I@4447|Liliopsida,3I8NK@38820|Poales	35493|Streptophyta	S	plant mutator transposase zinc finger	-	-	-	ko:K17604	-	-	-	-	ko00000,ko01009	-	-	-	DBD_Tnp_Mut,MULE,PB1,SWIM
k59_214668_2	4555.Si004528m	8.93e-09	62.0	28JZP@1|root,2QSE3@2759|Eukaryota,37QZD@33090|Viridiplantae,3GGZ7@35493|Streptophyta,3M4I6@4447|Liliopsida,3IBYT@38820|Poales	35493|Streptophyta	S	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DBD_Tnp_Mut,MULE,PMD
k59_175917_1	1054213.HMPREF9946_00921	8.31e-53	169.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria,2JT8J@204441|Rhodospirillales	204441|Rhodospirillales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_175917_2	1265505.ATUG01000001_gene3062	3.36e-18	80.5	COG1942@1|root,COG1942@2|Bacteria,1NAGG@1224|Proteobacteria,42SUX@68525|delta/epsilon subdivisions,2WPAH@28221|Deltaproteobacteria,2MK8R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_191548_1	1423755.BAML01000021_gene1255	4.88e-86	272.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,3F426@33958|Lactobacillaceae	91061|Bacilli	C	Dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_13439_1	472759.Nhal_2032	2.17e-55	189.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales	135613|Chromatiales	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_152709_1	1049564.TevJSym_bv00110	2.12e-57	195.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1J5PE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_122084_1	1000565.METUNv1_01250	1.55e-20	97.4	2E11Z@1|root,32WHR@2|Bacteria,1N6I4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_245635_1	4081.Solyc00g049210.1.1	1.35e-169	488.0	COG1138@1|root,2QQ5D@2759|Eukaryota,37KAN@33090|Viridiplantae,3G7VB@35493|Streptophyta	35493|Streptophyta	O	cytochrome c	ccmFN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0017004,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_145559_1	395493.BegalDRAFT_2897	6.46e-59	206.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_13441_1	1305737.JAFX01000001_gene1501	1.08e-27	113.0	COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,47N77@768503|Cytophagia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
k59_82991_1	105559.Nwat_0947	3.08e-05	52.0	2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria,1S7HH@1236|Gammaproteobacteria,1WX2B@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
k59_122085_1	1232683.ADIMK_1232	1.24e-27	115.0	COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,1T42H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C13
k59_191550_1	1120965.AUBV01000009_gene2986	3.6e-78	244.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,47PFY@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the glycosyl hydrolase 13 family	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	AMPK1_CBM,CBM_48,Esterase
k59_229985_1	1238190.AMQY01000021_gene1593	3.68e-61	216.0	COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ORF located using Glimmer RBSfinder	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A,DNA_pol_A_exo1
k59_175928_1	629265.PMA4326_29977	3.31e-25	104.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1Z6XK@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	Q	Pyoverdine sidechain peptide synthetase II, D-Asp-L-Thr component	pvdI	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD
k59_29025_1	1165841.SULAR_07123	7.62e-44	152.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_29025_2	1165841.SULAR_07128	1.52e-222	615.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2YMR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_160523_1	1165841.SULAR_00820	2.42e-71	221.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,42SRW@68525|delta/epsilon subdivisions,2YPFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_160523_2	1165841.SULAR_00815	1.48e-53	173.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2YP9T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
k59_106150_1	1125863.JAFN01000001_gene1256	3.51e-93	288.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,43BD6@68525|delta/epsilon subdivisions,2X6S2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_214683_1	1340493.JNIF01000004_gene733	3.57e-07	57.8	COG2304@1|root,COG2304@2|Bacteria,3Y6C6@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_52186_1	2340.JV46_26190	9.37e-86	263.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1J549@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iSSON_1240.SSON_4131	Semialdhyde_dh,Semialdhyde_dhC
k59_222545_1	1236518.BAKP01000007_gene685	1.55e-20	100.0	COG3209@1|root,COG3209@2|Bacteria,4NGJF@976|Bacteroidetes,2FQPQ@200643|Bacteroidia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,Ribonuclease,SpvB,TcdB_toxin_midN,VCBS
k59_13451_1	1123502.AQXD01000001_gene1356	3.2e-15	72.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	ybaV	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.1.26.11	ko:K00784,ko:K02237	ko03013,map03013	M00429	-	-	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.11.1,3.A.11.2	-	-	HHH_3
k59_137263_1	396588.Tgr7_0794	8.15e-59	191.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1WXRS@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_21167_1	1236976.JCM16418_3440	4.42e-55	194.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1UEIC@1239|Firmicutes,4HDD8@91061|Bacilli,26RKT@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,Response_reg
k59_129745_1	1165841.SULAR_05278	2.45e-157	450.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_59942_1	1280953.HOC_18119	3.61e-87	275.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	MA20_01050	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3
k59_98737_1	264402.Cagra.0259s0008.1.p	2.27e-189	535.0	COG0356@1|root,KOG4665@2759|Eukaryota,37J5M@33090|Viridiplantae,3GEF0@35493|Streptophyta	35493|Streptophyta	C	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel	atp6-1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	ko:K02126	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko03029	3.A.2.1	-	-	ATP-synt_A
k59_21171_1	1165841.SULAR_00240	8.83e-125	360.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,42N9H@68525|delta/epsilon subdivisions,2YMGK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_240722_1	6500.XP_005102740.1	2.56e-90	295.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CZSS@33213|Bilateria	33208|Metazoa	G	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve,zf-H2C2
k59_39748_1	986075.CathTA2_0629	1e-53	172.0	COG1917@1|root,COG1917@2|Bacteria,1V719@1239|Firmicutes,4HIPQ@91061|Bacilli	91061|Bacilli	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
k59_117122_1	1232410.KI421415_gene3011	8.03e-68	229.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43RX7@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_209869_1	1117314.PCIT_12384	2.84e-05	43.1	2BI4W@1|root,32W3I@2|Bacteria,1N65T@1224|Proteobacteria,1SAHM@1236|Gammaproteobacteria,2Q4W6@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k59_32116_1	387093.SUN_1350	6.08e-131	397.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_32116_3	387093.SUN_1339	7.81e-09	53.9	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42U5E@68525|delta/epsilon subdivisions,2YPTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k59_202174_1	1168034.FH5T_07210	2.69e-59	191.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_24135_1	1165841.SULAR_03327	5.43e-88	266.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_78382_1	296591.Bpro_0575	3.18e-09	62.8	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VIJR@28216|Betaproteobacteria,4A9TN@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_147909_1	118166.JH976537_gene21	1.05e-18	94.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_39759_2	313598.MED152_07015	5.01e-17	80.9	28MJ4@1|root,2ZAVQ@2|Bacteria,4NJ2U@976|Bacteroidetes,1I195@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_240737_2	1165841.SULAR_08849	5.32e-81	250.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2YMEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k59_117137_1	395493.BegalDRAFT_0442	6.75e-74	249.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_240738_1	2340.JV46_13820	7.95e-120	347.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1JA45@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_39764_1	1121937.AUHJ01000036_gene2809	7.97e-35	131.0	COG2801@1|root,COG2801@2|Bacteria,1R6TH@1224|Proteobacteria,1RRWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
k59_39764_2	631362.Thi970DRAFT_03296	1.44e-119	346.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,1S518@1236|Gammaproteobacteria,1X0QD@135613|Chromatiales	1236|Gammaproteobacteria	U	Type II secretory pathway, component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_202178_1	387093.SUN_1224	2.14e-34	125.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065	OstA
k59_70559_1	398512.JQKC01000001_gene2091	8.44e-61	197.0	COG0616@1|root,COG0616@2|Bacteria,1U2Z9@1239|Firmicutes,24DAF@186801|Clostridia,3WQCK@541000|Ruminococcaceae	186801|Clostridia	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
k59_70559_2	1190603.AJYD01000063_gene835	1.6e-10	60.8	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XUA3@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_70560_1	1123518.ARWI01000001_gene1637	7.34e-08	58.5	COG2834@1|root,COG2834@2|Bacteria,1R8JU@1224|Proteobacteria,1SKB0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_32140_1	2340.JV46_08220	7.51e-83	251.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1J5U7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
k59_32140_2	765913.ThidrDRAFT_3933	6.46e-56	178.0	COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1WY49@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_78410_2	1415754.JQMK01000012_gene1033	1.7e-93	281.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria,466HZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	ZIP Zinc transporter	zupT	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	iECIAI39_1322.ECIAI39_3536	Zip
k59_86138_1	1165841.SULAR_01573	1.69e-46	159.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42YUF@68525|delta/epsilon subdivisions,2YR9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_8809_1	395493.BegalDRAFT_0437	2.56e-117	359.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,GAF,GAF_2,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,Response_reg
k59_55221_1	765911.Thivi_1064	2.34e-76	258.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
k59_217723_2	1168034.FH5T_12910	1.45e-84	251.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,2FSJF@200643|Bacteroidia	976|Bacteroidetes	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_225697_1	398720.MED217_17130	2.03e-99	305.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,2XJHM@283735|Leeuwenhoekiella	976|Bacteroidetes	F	Ribonucleotide reductase, barrel domain	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_47816_1	1411123.JQNH01000001_gene1855	6.29e-10	67.4	COG4461@1|root,COG4461@2|Bacteria,1R0Z2@1224|Proteobacteria,2TYV9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
k59_78742_1	1122604.JONR01000025_gene4560	9.6e-103	311.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1X3KZ@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_156017_1	118168.MC7420_860	3.19e-45	161.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Trypsin_2
k59_32576_1	398579.Spea_2407	8.8e-18	87.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,2Q9VP@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM Peptidoglycan-binding LysM	mltD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_94276_1	875328.JDM601_2443	1.29e-26	108.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,233KN@1762|Mycobacteriaceae	201174|Actinobacteria	G	catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor	ppgK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0040007,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0047330,GO:0051156,GO:0071704,GO:1901135	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_40175_2	1233488.S4T7A1_9CAUD	4.66e-29	109.0	4QEW9@10239|Viruses,4QWFV@35237|dsDNA viruses  no RNA stage,4QRGP@28883|Caudovirales,4QNCN@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132853_1	709032.Sulku_0015	5.8e-19	93.2	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,42RST@68525|delta/epsilon subdivisions,2YPD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_101922_1	1121937.AUHJ01000014_gene2604	3.23e-63	207.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,4641S@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_241093_1	1501391.LG35_02575	1.17e-44	150.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,2FKZE@200643|Bacteroidia,22U72@171550|Rikenellaceae	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_117452_1	331678.Cphamn1_1862	1.55e-47	156.0	COG0607@1|root,COG0607@2|Bacteria,1FEK7@1090|Chlorobi	1090|Chlorobi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_132855_1	402777.KB235903_gene2607	8.13e-07	57.4	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HABM@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
k59_55568_1	2340.JV46_10860	7.02e-82	249.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1J5TJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
k59_55568_2	883126.HMPREF9710_04288	1.58e-20	85.5	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,47443@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_225708_1	1123236.KB899376_gene1009	2.13e-13	70.1	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,465ZM@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_40176_2	1122951.ATUE01000006_gene933	1e-13	67.4	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
k59_32589_1	1165841.SULAR_00995	3.82e-105	308.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_78758_1	1165841.SULAR_10014	3.31e-98	311.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_32590_1	983548.Krodi_2849	5.12e-75	236.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia,37EH3@326319|Dokdonia	976|Bacteroidetes	O	Glycoprotease family	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_163832_1	323848.Nmul_A2418	1.65e-84	258.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,371UX@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Exodeoxyribonuclease III xth	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_148306_1	1168034.FH5T_10340	1.11e-55	182.0	COG3177@1|root,COG3177@2|Bacteria,4NHPW@976|Bacteroidetes,2FQXS@200643|Bacteroidia	976|Bacteroidetes	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
k59_1419_1	1230457.C476_08243	6.4e-13	72.8	COG0034@1|root,COG0367@1|root,arCOG00071@2157|Archaea,arCOG00093@2157|Archaea,2XV5E@28890|Euryarchaeota,23WDA@183963|Halobacteria	183963|Halobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_40183_1	2340.JV46_19790	2.53e-82	258.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1J4SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Permease	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_187033_1	402626.Rpic_0863	3.51e-54	176.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,1KH15@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_101938_1	384765.SIAM614_14745	2.65e-13	66.2	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k59_101939_1	1049564.TevJSym_at00760	7.17e-85	266.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1J5F2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_179395_1	344747.PM8797T_15396	1.45e-11	69.3	COG5492@1|root,COG5492@2|Bacteria,2IXPF@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt2,PSD1
k59_32598_1	3694.POPTR_0015s09490.1	4.11e-16	85.5	COG0515@1|root,2QR0Z@2759|Eukaryota,37QZE@33090|Viridiplantae,3GFIA@35493|Streptophyta,4JGT2@91835|fabids	35493|Streptophyta	T	L-type lectin-domain containing receptor kinase	-	GO:0002229,GO:0002239,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005886,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0016020,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0071944,GO:0098542	-	-	-	-	-	-	-	-	-	-	Lectin_legB,Pkinase
k59_218108_1	933262.AXAM01000058_gene3193	1.04e-122	367.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42PPP@68525|delta/epsilon subdivisions,2WJ0H@28221|Deltaproteobacteria,2MPVY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
k59_202534_1	96561.Dole_0660	4.13e-94	292.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_94292_1	313596.RB2501_10005	5.01e-137	398.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1HWRR@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_233617_1	1385520.N802_18505	3.91e-24	107.0	COG1414@1|root,COG1414@2|Bacteria,2I3CC@201174|Actinobacteria,4FH5A@85021|Intrasporangiaceae	201174|Actinobacteria	K	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k59_32601_1	1121878.AUGL01000005_gene2717	5.12e-29	112.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k59_32601_2	395493.BegalDRAFT_2675	1.82e-59	185.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,460MU@72273|Thiotrichales	72273|Thiotrichales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_171661_1	765911.Thivi_1914	1.67e-41	148.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_171661_2	2340.JV46_18630	2.14e-13	66.6	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1JBXM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_4424_1	1469607.KK073768_gene2202	7.81e-55	198.0	COG0236@1|root,COG1028@1|root,COG2141@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG2141@2|Bacteria,1GQ2J@1117|Cyanobacteria	1117|Cyanobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	KR,PP-binding
k59_104594_1	1042876.PPS_4545	7.12e-31	121.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_166887_1	1049564.TevJSym_aq00060	1.3e-106	319.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1J4KI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_166887_2	323261.Noc_2650	5.87e-20	90.5	2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,1WZCE@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,DUF4124
k59_166887_3	2340.JV46_17570	4.86e-18	84.7	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1J4NI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	glnL	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_197811_1	1165841.SULAR_02893	1.52e-30	116.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_197811_2	1165841.SULAR_02888	6.26e-67	204.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_197811_3	1165841.SULAR_02883	3.13e-102	309.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_66082_1	1165841.SULAR_07335	8.5e-105	312.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YN0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_236396_1	331869.BAL199_29100	6.94e-15	78.6	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
k59_50500_1	1479237.JMLY01000001_gene3655	3.99e-103	301.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,1RR1E@1236|Gammaproteobacteria,464DR@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1989)	ycgI	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_66089_2	387093.SUN_0024	7.75e-83	246.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2YPMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_66089_3	1165841.SULAR_08617	1.92e-57	187.0	COG0506@1|root,COG0506@2|Bacteria,1Q2W5@1224|Proteobacteria,42WCB@68525|delta/epsilon subdivisions,2YQK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	proline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213060_1	395493.BegalDRAFT_2569	5.75e-105	319.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RSKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_4432_1	572477.Alvin_1995	9.5e-81	270.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k59_58231_1	886377.Murru_0923	3.19e-60	198.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
k59_128153_1	247634.GPB2148_3260	1.79e-143	408.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_27409_1	2340.JV46_28500	2.62e-133	387.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1J5B3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_213061_1	1165841.SULAR_02333	2.03e-96	300.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GGDEF,PAS_9,dCache_3
k59_120330_1	388413.ALPR1_10675	3.62e-14	71.2	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,47Q8Q@768503|Cytophagia	976|Bacteroidetes	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k59_120330_2	523791.Kkor_2602	8.05e-27	103.0	COG0454@1|root,COG0456@2|Bacteria,1N29T@1224|Proteobacteria,1S8SC@1236|Gammaproteobacteria,1XKK6@135619|Oceanospirillales	135619|Oceanospirillales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_166899_1	688270.Celal_3461	1.1e-63	208.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia,1F913@104264|Cellulophaga	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166899_2	1392489.JPOL01000002_gene720	5.78e-56	177.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia,2XJ5Y@283735|Leeuwenhoekiella	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_144021_1	879212.DespoDRAFT_02931	3.72e-67	221.0	28J8Y@1|root,2Z943@2|Bacteria,1REXC@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
k59_89571_1	518766.Rmar_1719	3.79e-05	47.4	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1FJBN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_89571_2	519989.ECTPHS_10696	3.43e-08	55.5	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_236783_1	4081.Solyc03g005540.1.1	1.47e-75	262.0	28JZP@1|root,2QSE3@2759|Eukaryota,37QZD@33090|Viridiplantae,3GGZ7@35493|Streptophyta	35493|Streptophyta	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	DBD_Tnp_Mut,MULE,SWIM
k59_128568_1	686578.AFFX01000005_gene4112	5.39e-40	136.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_66452_1	1541065.JRFE01000025_gene1965	2.12e-67	216.0	COG1397@1|root,COG1397@2|Bacteria,1G437@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ADP-ribosylglycohydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
k59_81966_1	1121405.dsmv_2362	1.05e-64	204.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria,2MJW5@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
k59_120771_1	1279017.AQYJ01000021_gene2826	8.64e-32	124.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,466VC@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_120771_2	1297863.APJF01000030_gene806	2.5e-10	61.2	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3JRP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Efflux pump membrane transporter	MA20_26850	-	-	ko:K18299,ko:K18902,ko:K19594	-	M00641,M00698,M00768,M00769	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.16,2.A.6.2.25,2.A.6.2.34	-	-	ACR_tran
k59_244391_1	387093.SUN_0187	1.33e-49	176.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_244391_2	387093.SUN_0185	1.24e-25	105.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_198254_1	1340810.V5USR5_9CAUD	2.44e-29	115.0	4QHGY@10239|Viruses,4R0DU@35237|dsDNA viruses  no RNA stage,4QRJK@28883|Caudovirales,4QI22@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_198254_3	238854.Q5GQK2_BPSYP	2.57e-15	78.6	4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses  no RNA stage,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae	10662|Myoviridae	S	DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89578_1	1131730.BAVI_13919	3.07e-14	76.6	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZB6P@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_12291_1	1165841.SULAR_09104	6.46e-98	302.0	COG2199@1|root,COG2203@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,1RGKE@1224|Proteobacteria,43CM2@68525|delta/epsilon subdivisions,2YTK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,Response_reg
k59_50920_2	1231391.AMZF01000017_gene177	5.83e-19	83.2	COG1846@1|root,COG1846@2|Bacteria,1N150@1224|Proteobacteria,2VVF3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Regulatory protein MarR	hcaR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_198262_1	1068980.ARVW01000001_gene1412	8.74e-05	48.5	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4E10P@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
k59_198262_2	566466.NOR53_3619	4.23e-16	79.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1JBW7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_35746_1	1165841.SULAR_05163	8.75e-64	196.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,42TRM@68525|delta/epsilon subdivisions,2YQ2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1393 Arsenate reductase and related	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_43322_1	426355.Mrad2831_4764	2.2e-53	187.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TS14@28211|Alphaproteobacteria,1JUDI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_89584_1	391598.FBBAL38_00790	1.32e-43	150.0	2DC7W@1|root,2ZD7C@2|Bacteria,4NMMW@976|Bacteroidetes,1I1HS@117743|Flavobacteriia	976|Bacteroidetes	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k59_89584_2	983545.Glaag_1635	8.52e-21	90.1	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,4640J@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	yhdH	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_228841_1	385682.AFSL01000060_gene1820	1.34e-102	305.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,2FMFT@200643|Bacteroidia,3XJMG@558415|Marinilabiliaceae	976|Bacteroidetes	J	Queuosine biosynthesis protein	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_136126_1	1168034.FH5T_12160	1.78e-24	95.1	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,2FT2Q@200643|Bacteroidia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_136126_2	1168034.FH5T_12155	2.03e-66	205.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,2FNEJ@200643|Bacteroidia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_66476_1	443152.MDG893_14243	1.53e-33	118.0	COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,1SEAC@1236|Gammaproteobacteria,46CX7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Helix-turn-helix domain	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_66476_2	1121022.ABENE_23525	2.05e-39	140.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2KGFM@204458|Caulobacterales	204458|Caulobacterales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_128588_1	1165841.SULAR_05193	1.95e-78	257.0	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_81979_1	1165841.SULAR_03183	2.52e-79	249.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2YN3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_81979_2	1165841.SULAR_03178	1.35e-15	74.7	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2YPTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3786 conserved	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_27814_1	1341181.FLJC2902T_17070	9.1e-36	124.0	COG3422@1|root,COG3422@2|Bacteria,4NS9J@976|Bacteroidetes,1I40P@117743|Flavobacteriia,2NWQW@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF1508)	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
k59_205775_1	1121904.ARBP01000030_gene1984	2.22e-39	150.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,His_kinase,Reg_prop,Y_Y_Y
k59_105015_1	1165841.SULAR_01460	2.15e-32	122.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2YNK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_105015_2	387093.SUN_1433	7.77e-134	396.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_112978_1	472759.Nhal_2383	5.62e-136	394.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1WWIK@135613|Chromatiales	135613|Chromatiales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_198276_2	627192.SLG_06240	5.79e-29	107.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,2K5VY@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
k59_244411_1	1165841.SULAR_00120	6.62e-181	536.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_89594_1	929712.KI912613_gene106	9.16e-15	76.6	COG1309@1|root,COG1309@2|Bacteria,2IB4X@201174|Actinobacteria,4CSQ6@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_12312_1	457424.BFAG_02965	3.03e-12	71.2	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,4ANIK@815|Bacteroidaceae	976|Bacteroidetes	O	Psort location Periplasmic, score	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
k59_43350_1	765914.ThisiDRAFT_0425	3.35e-31	118.0	COG3617@1|root,COG3646@1|root,COG3617@2|Bacteria,COG3646@2|Bacteria,1N7SM@1224|Proteobacteria,1RRD1@1236|Gammaproteobacteria,1X1Z0@135613|Chromatiales	135613|Chromatiales	K	PFAM Phage regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_pRha
k59_198289_1	398767.Glov_3572	1.85e-55	176.0	COG1487@1|root,COG1487@2|Bacteria,1N44Q@1224|Proteobacteria,42UNG@68525|delta/epsilon subdivisions,2WRVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_198289_2	227377.CBU_1295	1.09e-19	83.6	COG4118@1|root,COG4118@2|Bacteria,1QTA8@1224|Proteobacteria,1SUJ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_198289_3	1123400.KB904790_gene216	1.49e-40	150.0	COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1S4ZG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
k59_221365_1	1165841.SULAR_08362	3.9e-30	114.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2YN3J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_221365_2	1165841.SULAR_08357	1.17e-41	145.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2YMNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudouridine synthase	sfhB	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_239104_1	713586.KB900536_gene2508	3.99e-77	242.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales	135613|Chromatiales	GM	NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_239105_1	1485545.JQLW01000007_gene727	2.35e-88	278.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria	1224|Proteobacteria	S	fad dependent oxidoreductase	IV02_08645	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,FAD_binding_3,Pyr_redox_2
k59_123237_1	1165841.SULAR_03757	1.3e-116	347.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_184954_1	1165841.SULAR_05593	5.94e-74	228.0	COG2177@1|root,COG2177@2|Bacteria,1R85B@1224|Proteobacteria,42PX3@68525|delta/epsilon subdivisions,2YQ4H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
k59_184954_2	1165841.SULAR_05588	6.56e-34	130.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_246677_1	1123366.TH3_16179	1.21e-94	299.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2JPYX@204441|Rhodospirillales	204441|Rhodospirillales	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_153831_1	1168034.FH5T_01140	4.57e-77	246.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,2FMFZ@200643|Bacteroidia	976|Bacteroidetes	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_7007_1	1305737.JAFX01000001_gene1268	1.07e-68	228.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,47MK3@768503|Cytophagia	976|Bacteroidetes	S	glutamate carboxypeptidase	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
k59_161671_1	1243664.CAVL020000006_gene4960	3.45e-17	83.6	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	gtaB	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_161671_2	1121377.KB906405_gene31	2.5e-11	66.6	COG1847@1|root,COG1847@2|Bacteria,1WJEC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
k59_161671_3	349106.PsycPRwf_2388	1.01e-24	104.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,3NIHW@468|Moraxellaceae	1236|Gammaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_176962_1	4558.Sb06g013680.1	1.25e-226	695.0	COG2801@1|root,KOG0017@2759|Eukaryota,38A58@33090|Viridiplantae,3GXPE@35493|Streptophyta,3MB5P@4447|Liliopsida,3IUQY@38820|Poales	35493|Streptophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVP,RVT_1,zf-CCHC
k59_84135_1	1042377.AFPJ01000051_gene87	8.89e-204	577.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,46DHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_208060_1	765911.Thivi_3299	5.21e-102	313.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k59_208060_2	765911.Thivi_3300	6.86e-26	99.4	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,1S3TG@1236|Gammaproteobacteria,1X27P@135613|Chromatiales	135613|Chromatiales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
k59_68903_1	1173028.ANKO01000008_gene2104	7.91e-20	90.5	COG0642@1|root,COG3829@1|root,COG4251@1|root,COG0642@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_2,PAS_3,PAS_9,PHY,Response_reg
k59_123622_1	1168034.FH5T_05795	4.6e-79	263.0	COG3250@1|root,COG3250@2|Bacteria,4NKZX@976|Bacteroidetes,2FNTC@200643|Bacteroidia	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
k59_84513_1	1121937.AUHJ01000032_gene3070	4.44e-106	308.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,46765@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_170106_1	706587.Desti_3122	4.39e-75	239.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MQAH@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_239492_1	177437.HRM2_25410	2.38e-81	257.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1R97Q@1224|Proteobacteria,42UH7@68525|delta/epsilon subdivisions,2X6SD@28221|Deltaproteobacteria,2MPID@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_61432_1	563040.Saut_1309	1.1e-126	377.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_77103_1	1556290.A0A0A0RM00_9CAUD	2.51e-79	255.0	4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae	10699|Siphoviridae	S	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_92258_1	1254432.SCE1572_19160	4.94e-43	160.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42MK8@68525|delta/epsilon subdivisions,2WMI7@28221|Deltaproteobacteria,2YY33@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_138698_1	1168034.FH5T_14160	1.62e-11	64.3	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,2FN3J@200643|Bacteroidia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_138698_2	1168034.FH5T_14165	3.17e-85	253.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,2FN36@200643|Bacteroidia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_131225_1	765910.MARPU_07365	6.75e-72	228.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1X04E@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_239499_1	1265505.ATUG01000002_gene2290	5.86e-40	135.0	COG2329@1|root,COG2329@2|Bacteria,1N397@1224|Proteobacteria,42UGH@68525|delta/epsilon subdivisions,2WQH6@28221|Deltaproteobacteria,2MKEX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_45972_1	1165841.SULAR_00280	4.55e-44	155.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_45972_2	387631.Asulf_01417	1.23e-16	82.8	arCOG02559@1|root,arCOG03888@1|root,arCOG07824@1|root,arCOG02559@2157|Archaea,arCOG03888@2157|Archaea,arCOG07824@2157|Archaea,2Y689@28890|Euryarchaeota,24746@183980|Archaeoglobi	183980|Archaeoglobi	S	by modhmm	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162033_1	1231391.AMZF01000032_gene639	4.27e-23	93.2	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,3T3XE@506|Alcaligenaceae	28216|Betaproteobacteria	L	3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_61441_1	2340.JV46_25230	1.51e-50	173.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_224009_1	472759.Nhal_1179	1.95e-08	54.7	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1WXT6@135613|Chromatiales	135613|Chromatiales	I	PFAM phosphoesterase PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k59_224009_2	391603.FBALC1_11467	9.31e-23	98.2	COG0457@1|root,COG0457@2|Bacteria,4NJ7M@976|Bacteroidetes,1I0QV@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_6,TPR_8
k59_92262_1	2340.JV46_13500	6.94e-113	341.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1J5CM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_231410_1	1165841.SULAR_03218	1.51e-86	264.0	COG1792@1|root,COG1792@2|Bacteria,1QB26@1224|Proteobacteria,42MF4@68525|delta/epsilon subdivisions,2YNT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_231410_2	749222.Nitsa_1220	2.09e-40	142.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2YMHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	rod shape-determining protein mreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_53638_1	211165.AJLN01000149_gene6650	1.3e-53	192.0	COG0500@1|root,COG3321@1|root,COG2226@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1JKSY@1189|Stigonemataceae	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_208445_1	630626.EBL_c08100	9e-24	106.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_177332_1	378806.STAUR_4928	1.55e-51	187.0	COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria,1N0QS@1224|Proteobacteria	1224|Proteobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADC,Amino_oxidase,NAD_binding_8
k59_193067_1	177437.HRM2_43240	1.3e-54	201.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2MIPM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
k59_231418_1	1165841.SULAR_01728	2.19e-61	201.0	28JJP@1|root,2Z9CN@2|Bacteria	2|Bacteria	S	Peptidase M30	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M30
k59_216113_1	102129.Lepto7375DRAFT_8081	5.04e-31	125.0	COG5297@1|root,COG5297@2|Bacteria,1G4R7@1117|Cyanobacteria,1HHYE@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolase family 9	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
k59_131237_1	318161.Sden_3680	9.12e-30	117.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,2Q9MT@267890|Shewanellaceae	1236|Gammaproteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_22703_1	313628.LNTAR_12216	2.98e-55	206.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_61458_1	1250232.JQNJ01000001_gene3437	1.52e-21	96.3	2E3AK@1|root,320TI@2|Bacteria,4NRX2@976|Bacteroidetes,1IIAU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_216119_1	234267.Acid_2265	1.23e-51	177.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
k59_38534_1	641526.ADIWIN_1391	3.58e-84	263.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_77136_1	509191.AEDB02000067_gene912	1e-13	75.1	COG1680@1|root,COG1680@2|Bacteria,1TRPT@1239|Firmicutes,2495H@186801|Clostridia,3WJHE@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF302
k59_200965_1	1165841.SULAR_00005	2.83e-52	176.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2YMTB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_77142_1	1122176.KB903565_gene3227	1.07e-08	61.2	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_200971_2	742767.HMPREF9456_00356	2.13e-25	104.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,2FM29@200643|Bacteroidia,22XM1@171551|Porphyromonadaceae	976|Bacteroidetes	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k59_170131_2	84531.JMTZ01000006_gene3495	2.57e-22	94.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1X4FI@135614|Xanthomonadales	135614|Xanthomonadales	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_14849_1	102107.XP_008245779.1	9.21e-16	76.3	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta,4JS2T@91835|fabids	35493|Streptophyta	C	Ribulose bisphosphate carboxylase, large chain	rbcL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.1.3.15,4.1.1.39,6.4.1.2	ko:K01601,ko:K01963	ko00061,ko00620,ko00630,ko00640,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00630,map00640,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00165,M00166,M00376,M00532	R00024,R00742,R03140,R04386	RC00040,RC00172,RC00253,RC00367,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_30663_1	457398.HMPREF0326_05741	5.08e-32	122.0	COG3293@1|root,COG3385@1|root,COG3293@2|Bacteria,COG3385@2|Bacteria,1P5HD@1224|Proteobacteria,42TZG@68525|delta/epsilon subdivisions,2WQT4@28221|Deltaproteobacteria,2MC3W@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_30663_2	63737.Npun_R2130	3.43e-11	65.1	COG3293@1|root,COG3293@2|Bacteria,1FZVT@1117|Cyanobacteria,1HNVV@1161|Nostocales	1117|Cyanobacteria	L	COGs COG3293 Transposase and inactivated derivatives	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_162052_1	1165841.SULAR_01673	1.6e-57	185.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2YMK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_162052_2	1165841.SULAR_01678	6.46e-53	177.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_30664_1	1165841.SULAR_02883	5.03e-114	340.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_231423_1	999141.GME_17422	2.49e-151	451.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria,1XHBF@135619|Oceanospirillales	135619|Oceanospirillales	LV	RNA-directed DNA polymerase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k59_22719_1	1121935.AQXX01000110_gene5464	5.46e-87	287.0	COG2373@1|root,COG3755@1|root,COG2373@2|Bacteria,COG3755@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,LprI,MG1
k59_46002_1	4096.XP_009794768.1	0.000201	47.8	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta	35493|Streptophyta	E	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3,rve
k59_46002_2	3750.XP_008353911.1	2.57e-11	64.7	COG2801@1|root,KOG1339@1|root,KOG0017@2759|Eukaryota,KOG1339@2759|Eukaryota,37NAX@33090|Viridiplantae,3GB83@35493|Streptophyta,4JJHE@91835|fabids	35493|Streptophyta	O	Belongs to the peptidase A1 family	-	GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0016020,GO:0016787,GO:0019538,GO:0030163,GO:0031224,GO:0031225,GO:0031226,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046658,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K00924	-	-	-	-	ko00000,ko01000	-	-	-	TAXi_C,TAXi_N
k59_115631_1	1049564.TevJSym_ac00940	3.4e-76	249.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1J4SW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_7471_1	313596.RB2501_14364	1.38e-10	62.8	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M_N
k59_177351_1	1123393.KB891331_gene2845	2.11e-40	145.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,1KSW1@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_118912_1	945713.IALB_1501	1.83e-97	304.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_2915_1	104623.Ser39006_01460	1.28e-50	172.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,400K9@613|Serratia	1236|Gammaproteobacteria	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_235015_1	1279038.KB907337_gene210	6.08e-53	175.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U3AH@28211|Alphaproteobacteria,2JRIM@204441|Rhodospirillales	204441|Rhodospirillales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_3,Fer4_8
k59_227051_1	1168034.FH5T_20980	1.77e-14	68.2	COG3304@1|root,COG3304@2|Bacteria,4NQSS@976|Bacteroidetes,2FTAX@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YccF
k59_49108_1	1125863.JAFN01000001_gene1310	1.55e-80	259.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,42NBQ@68525|delta/epsilon subdivisions,2WKR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Serine protein kinase	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_10666_1	880071.Fleli_2723	5.3e-36	139.0	COG1257@1|root,COG1257@2|Bacteria,4NGN1@976|Bacteroidetes,47NJ8@768503|Cytophagia	976|Bacteroidetes	I	hydroxymethylglutaryl-CoA reductase	hmgA	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
k59_196333_1	395493.BegalDRAFT_0253	3.05e-137	402.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4607S@72273|Thiotrichales	72273|Thiotrichales	T	nitrogen regulation protein NR(I)	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_142054_1	935557.ATYB01000008_gene4833	3.06e-40	152.0	COG2267@1|root,COG2303@1|root,COG3540@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,COG3540@2|Bacteria,1QQ8F@1224|Proteobacteria,2U7D4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EI	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_219419_1	768671.ThimaDRAFT_3229	3.29e-49	169.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1WZ6F@135613|Chromatiales	135613|Chromatiales	M	polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_188486_1	1168034.FH5T_10705	1.19e-10	61.2	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FPA0@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k59_188486_2	1408473.JHXO01000010_gene3700	7.43e-27	111.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,2FM98@200643|Bacteroidia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_41557_1	1210884.HG799464_gene10366	7.9e-81	258.0	COG5433@1|root,COG5433@2|Bacteria,2IWUI@203682|Planctomycetes	203682|Planctomycetes	L	COG5433 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_134221_1	340.xcc-b100_1276	7.62e-61	199.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X4E4@135614|Xanthomonadales	135614|Xanthomonadales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_33985_1	1122212.AULO01000013_gene1896	3.39e-30	117.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XIT8@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_33985_2	1049564.TevJSym_ag00370	1.98e-41	144.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1J4PJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0422	IGPS
k59_25985_1	758.BBIX01000009_gene1917	2.02e-13	69.3	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1YA0F@135625|Pasteurellales	135625|Pasteurellales	S	UPF0070 protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_25985_2	1144325.PMI22_01650	3.09e-50	173.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	histidyl-tRNA synthetase	hisS	GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358	HGTP_anticodon,tRNA-synt_His
k59_196334_2	28229.ND2E_1534	1.14e-31	122.0	COG1226@1|root,32Y28@2|Bacteria,1NEAT@1224|Proteobacteria,1S588@1236|Gammaproteobacteria,2Q6SK@267889|Colwelliaceae	1236|Gammaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
k59_242615_2	439235.Dalk_5241	3.5e-51	164.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,42URZ@68525|delta/epsilon subdivisions,2WQ58@28221|Deltaproteobacteria,2MKGK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_242615_3	439235.Dalk_4515	6.65e-43	156.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,43CRI@68525|delta/epsilon subdivisions,2X7Z7@28221|Deltaproteobacteria,2MIWI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_111087_1	4081.Solyc00g020040.1.1	2.12e-75	229.0	2C63N@1|root,2QT9Q@2759|Eukaryota,37P22@33090|Viridiplantae,3GH9T@35493|Streptophyta	35493|Streptophyta	-	-	ccmB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	-	-	-	-	-	-	-	-	-	-
k59_18040_1	1123073.KB899241_gene3530	1.32e-30	116.0	2BYAB@1|root,32R2Z@2|Bacteria,1QCT6@1224|Proteobacteria,1T8K3@1236|Gammaproteobacteria,1XAVH@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103263_1	1165841.SULAR_02513	8.85e-300	825.0	COG0834@1|root,COG1073@1|root,COG0834@2|Bacteria,COG1073@2|Bacteria,1N3ZN@1224|Proteobacteria,42VWV@68525|delta/epsilon subdivisions	1224|Proteobacteria	ET	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_219431_1	395493.BegalDRAFT_0777	3.24e-82	247.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,460P5@72273|Thiotrichales	72273|Thiotrichales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_118928_1	1168034.FH5T_07890	6.2e-47	159.0	2C1B9@1|root,32R9M@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
k59_118928_2	688246.Premu_0432	2.14e-16	81.6	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,2FMY8@200643|Bacteroidia	976|Bacteroidetes	NU	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_219437_1	1165841.SULAR_02578	1.39e-68	212.0	28K10@1|root,2Z9QW@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
k59_142058_1	1249627.D779_2570	3.1e-138	403.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1WWFP@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k59_142058_2	1504981.KO116_4679	3.99e-48	160.0	COG3415@1|root,COG3415@2|Bacteria,1QUXF@1224|Proteobacteria,1T24W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_41559_2	1245471.PCA10_11480	1.02e-40	155.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1YDPR@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_41559_3	2340.JV46_06670	3.14e-49	169.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1J4NG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_103270_1	1304275.C41B8_08660	2.11e-79	252.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etfD	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
k59_111098_2	1121937.AUHJ01000007_gene1956	4.21e-47	158.0	2DBQY@1|root,2ZAHD@2|Bacteria,1QYTK@1224|Proteobacteria,1T3V2@1236|Gammaproteobacteria,46DA3@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_18051_1	583355.Caka_2626	6.79e-10	63.9	COG1228@1|root,COG1228@2|Bacteria,46U64@74201|Verrucomicrobia,3KA1D@414999|Opitutae	2|Bacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_196344_1	439235.Dalk_3317	4.72e-100	300.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJUN@28221|Deltaproteobacteria,2MIK6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_72326_1	2340.JV46_27010	9.55e-106	318.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria,1J4S8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Malate:quinone oxidoreductase (Mqo)	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
k59_95672_2	247633.GP2143_16886	7.05e-29	113.0	COG1028@1|root,COG1028@2|Bacteria,1REA0@1224|Proteobacteria,1SMHH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_33995_1	1121875.KB907547_gene3136	6.28e-169	505.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1HXEG@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_103276_1	1165841.SULAR_10094	6.73e-159	448.0	COG1999@1|root,COG1999@2|Bacteria,1R9EM@1224|Proteobacteria,42N5F@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
k59_219448_1	1166018.FAES_3612	1.2e-35	135.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95976_1	1094715.CM001373_gene2999	3.09e-42	149.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1JDJA@118969|Legionellales	118969|Legionellales	F	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_95976_2	1123519.PSJM300_00360	1.97e-22	96.7	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0JM@1236|Gammaproteobacteria,1Z2GR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
k59_204254_1	935567.JAES01000002_gene622	2.55e-64	216.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales	135614|Xanthomonadales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_34306_1	1215092.PA6_012_01160	7.97e-10	67.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1YFEW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	7TM diverse intracellular signalling	mmoS	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE5,HATPase_c,HisKA,Response_reg
k59_57155_1	1458275.AZ34_02675	5.13e-74	228.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
k59_57155_2	187272.Mlg_0503	4.47e-07	50.4	COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,1RNHW@1236|Gammaproteobacteria,1WXBX@135613|Chromatiales	135613|Chromatiales	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_111426_1	1165841.SULAR_09764	3.84e-172	489.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_242895_1	395493.BegalDRAFT_0005	1.33e-41	143.0	COG0639@1|root,COG0639@2|Bacteria,1RF21@1224|Proteobacteria,1S4CI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
k59_196681_1	1168034.FH5T_10255	5.15e-145	437.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,2FMGF@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_134542_1	395493.BegalDRAFT_1593	1.69e-05	46.2	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,Response_reg
k59_134542_2	857087.Metme_1124	3.16e-51	192.0	COG0515@1|root,COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
k59_10968_1	1232410.KI421412_gene178	2.04e-84	275.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43S5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_18357_1	395495.Lcho_3036	1.28e-12	70.5	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2VM4U@28216|Betaproteobacteria,1KM3B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_18357_2	1123401.JHYQ01000009_gene2218	2.25e-16	72.4	COG2920@1|root,COG2920@2|Bacteria,1RITK@1224|Proteobacteria,1S609@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_57160_1	1121413.JMKT01000002_gene2663	3.25e-27	111.0	COG1613@1|root,COG1613@2|Bacteria,1QWXU@1224|Proteobacteria,42YDY@68525|delta/epsilon subdivisions,2WTQN@28221|Deltaproteobacteria,2MHIN@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
k59_49469_1	395493.BegalDRAFT_0258	8.89e-49	170.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02461,ko:K02662,ko:K02663,ko:K12289	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilN
k59_26287_1	869213.JCM21142_62415	8.98e-74	244.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,47K7I@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_34316_1	247633.GP2143_08960	1.24e-35	130.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1J622@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_34316_2	1121116.KB894766_gene213	1.12e-09	61.2	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,4AA57@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
k59_173271_1	398580.Dshi_1709	2.45e-130	385.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2U3WC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
k59_49474_1	456442.Mboo_2278	6.2e-23	103.0	COG1132@1|root,arCOG02841@2157|Archaea,2XSW0@28890|Euryarchaeota	28890|Euryarchaeota	P	COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_235365_1	1165841.SULAR_00210	9.07e-94	278.0	COG0204@1|root,COG0204@2|Bacteria,1QAEF@1224|Proteobacteria,42YDI@68525|delta/epsilon subdivisions,2YREE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_49481_1	28229.ND2E_1561	2.07e-24	96.7	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,2Q5W2@267889|Colwelliaceae	1236|Gammaproteobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_18369_1	1168034.FH5T_09555	8.78e-14	70.1	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,2FPYA@200643|Bacteroidia	976|Bacteroidetes	H	Bifunctional protein	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_18369_2	1168034.FH5T_09550	3.25e-147	418.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,2FMX2@200643|Bacteroidia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_119283_2	7668.SPU_025609-tr	1.35e-61	215.0	2CMP4@1|root,2QR56@2759|Eukaryota,39VQX@33154|Opisthokonta,3BR69@33208|Metazoa,3D755@33213|Bilateria	33208|Metazoa	S	Pao retrotransposon peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_26298_2	1408433.JHXV01000009_gene1313	7.69e-32	116.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,1IMRK@117743|Flavobacteriia,2PBRK@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
k59_238073_1	765911.Thivi_3315	1.42e-07	53.1	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1WVVC@135613|Chromatiales	135613|Chromatiales	F	TIGRFAM dihydroorotase, multifunctional complex type	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_238073_2	2340.JV46_15670	1.18e-81	251.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1J4H1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_168760_1	743722.Sph21_2908	4.15e-78	248.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,1IP31@117747|Sphingobacteriia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_230112_1	1168034.FH5T_17785	7.62e-54	178.0	COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,2FQY6@200643|Bacteroidia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
k59_168761_1	1165841.SULAR_03347	4.45e-109	317.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_168761_2	1165841.SULAR_03352	7.46e-33	114.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,42V3S@68525|delta/epsilon subdivisions,2YQ9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
k59_5982_2	1502724.FF80_01862	3.08e-12	69.3	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3N7Q3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k59_152829_1	1408473.JHXO01000007_gene947	7.33e-42	153.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,2FNXT@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_137364_1	395493.BegalDRAFT_1404	9.26e-14	70.1	COG4642@1|root,COG4642@2|Bacteria	2|Bacteria	S	regulation of ryanodine-sensitive calcium-release channel activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN,PEGA
k59_29180_1	1121875.KB907549_gene1918	8.97e-58	189.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98894_1	4081.Solyc10g061880.1.1	1.04e-11	61.6	2CKIM@1|root,2SWMP@2759|Eukaryota,381WT@33090|Viridiplantae,3GRR6@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_106301_1	497964.CfE428DRAFT_5029	1.03e-59	192.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_152832_1	768671.ThimaDRAFT_0094	3.41e-124	378.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1WXGJ@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_60070_1	886377.Murru_0844	2.05e-99	294.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
k59_60070_2	1348583.ATLH01000001_gene3626	8.88e-48	167.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia,1F8JY@104264|Cellulophaga	976|Bacteroidetes	S	GldM C-terminal domain	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
k59_168767_1	765910.MARPU_12555	1.36e-61	202.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1WYFN@135613|Chromatiales	135613|Chromatiales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,HMA
k59_160630_1	1524880.A0A076G697_9VIRU	6.8e-06	54.3	4QD1M@10239|Viruses	10239|Viruses	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_191657_2	95619.PM1_0217260	5.31e-16	77.4	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Succinyldiaminopimelate	dapC	-	2.6.1.17	ko:K14261,ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_29182_1	713586.KB900536_gene1616	2.04e-40	138.0	COG3193@1|root,COG3193@2|Bacteria,1RJ3X@1224|Proteobacteria,1S8FV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k59_29182_2	998674.ATTE01000001_gene2583	4.04e-32	121.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,45ZXT@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
k59_21338_1	1121405.dsmv_0026	1.23e-62	196.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2MJZR@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_145699_1	504487.JCM19302_2209	1.87e-72	246.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
k59_37123_1	472759.Nhal_0436	9.39e-79	254.0	COG0557@1|root,COG2345@1|root,COG0557@2|Bacteria,COG2345@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_21339_1	998674.ATTE01000001_gene964	3.59e-26	103.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,1RNBQ@1236|Gammaproteobacteria,461QZ@72273|Thiotrichales	72273|Thiotrichales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_52303_1	745411.B3C1_08781	2.23e-110	360.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,DUF285,FIVAR,PG_binding_1,Pertactin,Phage_fiber_2,Sel1,YSIRK_signal
k59_60075_1	1165841.SULAR_07795	1e-172	495.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_168776_1	203122.Sde_3689	3.48e-74	229.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,1RRYH@1236|Gammaproteobacteria,46AW8@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
k59_230129_2	1165841.SULAR_05423	1.21e-85	252.0	COG0727@1|root,COG0727@2|Bacteria,1N3F5@1224|Proteobacteria,42THI@68525|delta/epsilon subdivisions,2YPYY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_230129_3	1165841.SULAR_05428	9.45e-34	120.0	COG4123@1|root,COG4123@2|Bacteria,1RDSC@1224|Proteobacteria,42RIN@68525|delta/epsilon subdivisions,2YP8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_191665_1	313596.RB2501_10617	2.57e-103	304.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1HY7Y@117743|Flavobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_238099_1	1430440.MGMSRv2_1656	4.1e-11	68.6	COG1352@1|root,COG2201@1|root,COG2433@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2433@2|Bacteria,1NQTI@1224|Proteobacteria,2TRH8@28211|Alphaproteobacteria,2JQ72@204441|Rhodospirillales	204441|Rhodospirillales	NT	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
k59_152847_1	666685.R2APBS1_1385	2.61e-71	233.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,1RZQR@1236|Gammaproteobacteria,1XCEP@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
k59_37133_1	502025.Hoch_6444	1.68e-76	248.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_21344_1	247634.GPB2148_959	2.34e-35	132.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,1J5WF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
k59_90907_1	580332.Slit_2150	1.27e-67	216.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98912_1	1121937.AUHJ01000024_gene67	8.82e-181	513.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,1RQYT@1236|Gammaproteobacteria,465WD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k59_169221_1	1168034.FH5T_08575	7.52e-22	94.4	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,2FP1Q@200643|Bacteroidia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_130258_1	886379.AEWI01000018_gene1278	2.78e-81	259.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,2FM3Y@200643|Bacteroidia,3XIMJ@558415|Marinilabiliaceae	976|Bacteroidetes	F	Class II glutamine amidotransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
k59_91332_2	497321.C664_18037	5.83e-06	52.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,2KX20@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
k59_230516_1	619693.HMPREF6745_2352	7e-46	164.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia	976|Bacteroidetes	H	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF4301
k59_137699_1	1192034.CAP_3204	7.43e-30	126.0	COG3321@1|root,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42PEZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	synthase	pltC	-	-	ko:K12436	-	-	-	-	ko00000,ko01004	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_184430_1	666686.B1NLA3E_09380	0.000132	42.4	COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,4HN1R@91061|Bacilli,1ZQAX@1386|Bacillus	91061|Bacilli	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_184430_2	2340.JV46_02560	3.27e-35	123.0	2BTD9@1|root,32NJ9@2|Bacteria,1RJF8@1224|Proteobacteria,1S7B6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184430_3	396588.Tgr7_0344	1.64e-06	47.0	COG3795@1|root,COG3795@2|Bacteria,1RJJG@1224|Proteobacteria,1SFR9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_44992_1	1168034.FH5T_08845	2.82e-93	301.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FRGY@200643|Bacteroidia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_122605_1	1229780.BN381_80073	0.000209	44.7	COG1404@1|root,COG5184@1|root,COG1404@2|Bacteria,COG5184@2|Bacteria,2IG31@201174|Actinobacteria,3UXAU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	DOZ	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RCC1,RCC1_2,SLH
k59_44994_1	1168034.FH5T_10930	1.91e-16	77.8	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_44994_2	1168034.FH5T_10935	6.1e-79	241.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,2FM2M@200643|Bacteroidia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
k59_91337_1	1123242.JH636434_gene4773	4.5e-62	201.0	COG0152@1|root,COG0152@2|Bacteria,2IY7D@203682|Planctomycetes	203682|Planctomycetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_215203_1	1123487.KB892865_gene1380	6.63e-36	137.0	COG3170@1|root,COG3170@2|Bacteria,1PMRK@1224|Proteobacteria,2W7ZG@28216|Betaproteobacteria,2KZB6@206389|Rhodocyclales	206389|Rhodocyclales	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44997_1	1165841.SULAR_05993	1.73e-48	164.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_44997_2	1165841.SULAR_05988	2.2e-34	124.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2YP5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NOU	Peptidase A24	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_146143_2	518766.Rmar_1655	1.3e-69	219.0	COG0527@1|root,COG0527@2|Bacteria,4NJDY@976|Bacteroidetes	976|Bacteroidetes	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_91344_2	1123368.AUIS01000024_gene949	2.08e-34	132.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_122608_2	665032.C9DG24_9CAUD	1.74e-26	120.0	4QEE7@10239|Viruses,4QV59@35237|dsDNA viruses  no RNA stage,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_176401_2	1120966.AUBU01000001_gene853	3.5e-23	100.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_106749_1	1168034.FH5T_10180	7.34e-96	303.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,2FMFA@200643|Bacteroidia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_146150_1	948106.AWZT01000005_gene4338	2.1e-17	76.3	COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,2VVRR@28216|Betaproteobacteria,1K9MR@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpM	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_146150_2	312309.VF_0846	1.48e-26	100.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,1SCW1@1236|Gammaproteobacteria,1XYJA@135623|Vibrionales	135623|Vibrionales	IQ	acyl carrier protein	RS00794	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_6471_1	368407.Memar_0959	5.4e-40	146.0	COG1817@1|root,arCOG01395@2157|Archaea,2XT3W@28890|Euryarchaeota,2NAFU@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
k59_60496_1	765911.Thivi_3956	4.3e-48	167.0	COG0845@1|root,COG0845@2|Bacteria,1MWZ9@1224|Proteobacteria,1RM91@1236|Gammaproteobacteria,1WX23@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_13941_1	247490.KSU1_C0343	8.13e-21	97.1	COG1404@1|root,COG3534@1|root,COG1404@2|Bacteria,COG3534@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
k59_130282_1	1047013.AQSP01000103_gene1160	7.5e-52	183.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_153255_1	329726.AM1_3309	5.37e-78	251.0	COG0028@1|root,COG2146@1|root,COG0028@2|Bacteria,COG2146@2|Bacteria,1G4NB@1117|Cyanobacteria	1117|Cyanobacteria	EHP	Thiamine pyrophosphate enzyme, central domain	-	-	1.2.3.3	ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207	RC02745	ko00000,ko00001,ko01000	-	-	-	Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_122614_2	1396418.BATQ01000164_gene2041	6.22e-26	103.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
k59_166563_1	1536770.R50345_15195	1.54e-15	83.6	COG2207@1|root,COG2207@2|Bacteria,1UI1Z@1239|Firmicutes,4HC2Y@91061|Bacilli,26R40@186822|Paenibacillaceae	91061|Bacilli	K	AraC family transcriptional regulator	yneE	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_11722_1	519989.ECTPHS_14156	1.15e-27	107.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1WY4B@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_150780_1	344747.PM8797T_32255	9.54e-70	220.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
k59_212818_1	391615.ABSJ01000054_gene1465	2.4e-66	215.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1J4NS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_73512_1	1123053.AUDG01000013_gene1134	2.15e-05	52.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1S054@1236|Gammaproteobacteria,1X24N@135613|Chromatiales	135613|Chromatiales	L	C-5 cytosine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_methylase
k59_42650_1	886379.AEWI01000005_gene963	4.79e-82	273.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,2FNH9@200643|Bacteroidia,3XJ8U@558415|Marinilabiliaceae	976|Bacteroidetes	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_120096_1	1168034.FH5T_21795	1.53e-75	246.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FM06@200643|Bacteroidia	976|Bacteroidetes	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_50264_1	1449353.JQMQ01000005_gene1814	9.51e-16	81.3	COG0317@1|root,COG0317@2|Bacteria,2GP8E@201174|Actinobacteria,2NEHU@228398|Streptacidiphilus	201174|Actinobacteria	KT	Region found in RelA / SpoT proteins	relA2	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_228178_1	1121403.AUCV01000124_gene2974	5.78e-16	78.6	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2MMJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_228178_2	1121403.AUCV01000020_gene3085	1.99e-10	60.5	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_150788_1	589865.DaAHT2_0484	6.25e-39	144.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_65788_1	33178.CADATEAP00007211	4.72e-47	167.0	2BZ7G@1|root,2QXM6@2759|Eukaryota,38DKY@33154|Opisthokonta,3NYVX@4751|Fungi,3QQBX@4890|Ascomycota	4751|Fungi	G	Pectinolytic enzymes consist of four classes of enzymes pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity)	pelF	GO:0000272,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010393,GO:0016052,GO:0016829,GO:0016835,GO:0016837,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0045488,GO:0045490,GO:0047490,GO:0071704,GO:1901575	4.2.2.10	ko:K01732	-	-	-	-	ko00000,ko01000	-	-	-	CBM_1,Pec_lyase_C
k59_127899_1	1283300.ATXB01000001_gene1611	1.35e-19	86.3	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1XF0Z@135618|Methylococcales	135618|Methylococcales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_88995_1	395493.BegalDRAFT_0832	3.25e-69	232.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_27123_1	1121439.dsat_2482	9.54e-80	261.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,2M91S@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_73531_1	7739.XP_002611203.1	1.97e-05	48.9	KOG2177@1|root,KOG2177@2759|Eukaryota	2759|Eukaryota	O	zinc ion binding	-	-	2.3.2.27	ko:K10648,ko:K11997,ko:K12015	-	-	-	-	ko00000,ko01000,ko04121	-	-	-	NHL,zf-B_box,zf-C3HC4_4
k59_150791_1	247634.GPB2148_3267	8.33e-15	74.3	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1S56T@1236|Gammaproteobacteria,1J65E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	NlpB/DapX lipoprotein	-	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_150791_2	1278309.KB907101_gene606	2.25e-26	105.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XHES@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_81426_2	1168034.FH5T_10165	5.41e-66	213.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,2FNYP@200643|Bacteroidia	976|Bacteroidetes	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_104373_1	1168289.AJKI01000011_gene570	1.48e-35	131.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia,3XIRD@558415|Marinilabiliaceae	976|Bacteroidetes	T	Sigma-54 interaction domain	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_50275_1	349521.HCH_03234	7.76e-74	228.0	COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria,1XN13@135619|Oceanospirillales	135619|Oceanospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_50275_2	1532558.JL39_14340	6.25e-36	124.0	COG2350@1|root,COG2350@2|Bacteria,1PZSM@1224|Proteobacteria,2UGH8@28211|Alphaproteobacteria,4BN16@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_50275_3	1279038.KB907337_gene519	5.11e-43	145.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,2JQMB@204441|Rhodospirillales	204441|Rhodospirillales	L	COG2818 3-methyladenine DNA glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_228186_1	13035.Dacsa_1940	3.79e-25	105.0	COG0475@1|root,COG0475@2|Bacteria,1GCNG@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM Sodium hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_42666_2	161156.JQKW01000011_gene956	7.31e-08	57.0	COG1040@1|root,COG1040@2|Bacteria,2GH0G@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_104378_1	869213.JCM21142_62459	4.04e-83	258.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,47K1V@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
k59_57998_1	1165841.SULAR_07670	6.26e-62	201.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,42ZSN@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_57998_2	1165841.SULAR_07675	1.95e-41	149.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2YTAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_96776_1	1392498.JQLH01000001_gene3744	1.24e-61	208.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,2PGXD@252356|Maribacter	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
k59_182040_1	196164.23493383	1.12e-11	67.4	29WRJ@1|root,30ICM@2|Bacteria,2H09C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_158655_1	1049564.TevJSym_ah00520	8.12e-64	204.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1J5P8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_189633_1	118168.MC7420_8174	2.87e-70	221.0	COG0005@1|root,COG0005@2|Bacteria,1G1F3@1117|Cyanobacteria,1H85M@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_42681_1	1348583.ATLH01000031_gene1970	2.65e-81	248.0	COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,1HX1K@117743|Flavobacteriia,1F893@104264|Cellulophaga	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_166598_1	1165841.SULAR_00280	1.3e-113	338.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_228204_1	768706.Desor_3869	8.23e-07	52.8	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,FGE-sulfatase,Lactamase_B_2,PD40,Peptidase_S9
k59_96784_1	1168034.FH5T_10765	6.5e-78	240.0	COG3861@1|root,COG3861@2|Bacteria,4NPP5@976|Bacteroidetes	976|Bacteroidetes	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	PRC
k59_182055_1	1116472.MGMO_177c00020	4.44e-18	88.6	COG3321@1|root,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria,1XF86@135618|Methylococcales	135618|Methylococcales	Q	PFAM Beta-ketoacyl synthase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_65817_1	592029.DDD_3268	3.67e-21	92.8	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia,3HJMP@363408|Nonlabens	976|Bacteroidetes	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_65817_2	980584.AFPB01000124_gene2367	8.15e-49	158.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_27159_1	187303.BN69_3333	1.95e-11	66.6	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,36YH4@31993|Methylocystaceae	28211|Alphaproteobacteria	C	ATP synthase delta (OSCP) subunit	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_27159_2	1121448.DGI_0653	1.21e-09	62.8	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,2MB5V@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_27160_1	2340.JV46_14520	1.28e-62	206.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1J4DX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_27160_2	1400525.JNIU01000001_gene995	3.49e-13	69.7	COG0508@1|root,COG2609@1|root,COG0508@2|Bacteria,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,4BQKZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transketolase_N
k59_4173_1	598659.NAMH_0984	1.6e-62	205.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_205106_1	933262.AXAM01000040_gene1232	9.88e-10	60.5	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MHZN@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_205106_2	177437.HRM2_11180	5.3e-34	122.0	29GM5@1|root,303IT@2|Bacteria,1RG3T@1224|Proteobacteria,42RUX@68525|delta/epsilon subdivisions,2WNMJ@28221|Deltaproteobacteria,2MJY1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_174076_1	1168034.FH5T_15415	1.73e-31	120.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,2FMX6@200643|Bacteroidia	976|Bacteroidetes	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_174076_2	1168034.FH5T_15410	2.79e-21	89.0	2EQMK@1|root,33I7I@2|Bacteria,4NY3R@976|Bacteroidetes,2FVUP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_220699_1	1408473.JHXO01000008_gene2644	5.54e-97	298.0	COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,2FWM3@200643|Bacteroidia	976|Bacteroidetes	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_127931_1	1168034.FH5T_19750	4.37e-126	374.0	COG0527@1|root,COG0527@2|Bacteria,4PKFA@976|Bacteroidetes,2G3F2@200643|Bacteroidia	976|Bacteroidetes	E	Amino acid kinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_4181_1	517418.Ctha_0207	0.00015	49.7	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF3868
k59_127936_1	1239962.C943_00057	1.34e-33	134.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_205122_1	1168034.FH5T_01435	7.13e-101	298.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_212856_1	1165841.SULAR_07118	8.67e-101	295.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42RGE@68525|delta/epsilon subdivisions,2YT0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_73559_1	72664.XP_006409520.1	3.12e-36	124.0	2CVN9@1|root,2S4GY@2759|Eukaryota,37WBG@33090|Viridiplantae,3GKIW@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit 9, mitochondrial	ATP9	GO:0000276,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02128	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_C
k59_27176_2	1492737.FEM08_19650	2.04e-05	51.6	COG1216@1|root,COG1216@2|Bacteria,4NGNS@976|Bacteroidetes,1HYIH@117743|Flavobacteriia,2NT97@237|Flavobacterium	976|Bacteroidetes	S	glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_4200_1	1168034.FH5T_12940	3.53e-124	360.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_143417_1	1002367.HMPREF0673_01606	8.61e-30	124.0	COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,2FRC8@200643|Bacteroidia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_236169_1	713586.KB900536_gene66	1.12e-20	97.8	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales	135613|Chromatiales	NU	FimV C-terminal	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	TPR_19
k59_42691_1	1123242.JH636434_gene3183	4.01e-55	196.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2IYQE@203682|Planctomycetes	203682|Planctomycetes	IQ	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
k59_35593_1	269797.Mbar_A2626	4.83e-63	194.0	COG0720@1|root,arCOG02172@2157|Archaea,2XX1X@28890|Euryarchaeota,2NBDZ@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_135978_1	631362.Thi970DRAFT_04985	4.71e-61	205.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1R97Q@1224|Proteobacteria,1RRDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_112827_1	1165841.SULAR_03048	1.36e-35	134.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_97386_1	765914.ThisiDRAFT_1039	5.28e-49	177.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1WWD1@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_58553_2	1165841.SULAR_05783	1.38e-65	200.0	2B3E9@1|root,31W34@2|Bacteria,1MZ95@1224|Proteobacteria,42U85@68525|delta/epsilon subdivisions,2YQ41@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_50788_1	1168034.FH5T_08020	6.88e-53	174.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,2FNN2@200643|Bacteroidia	976|Bacteroidetes	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
k59_50788_2	1168034.FH5T_08025	1.1e-74	235.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,2FTQH@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_182552_1	323261.Noc_2613	9.78e-52	179.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1WWQB@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_12203_2	686340.Metal_0062	1.52e-15	75.9	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1XFDH@135618|Methylococcales	135618|Methylococcales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_236722_2	1116472.MGMO_101c00140	3.28e-33	120.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1XFF5@135618|Methylococcales	135618|Methylococcales	J	Belongs to the HSP15 family	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
k59_205650_1	1444770.AF72_07905	1.61e-21	95.5	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1T042@1236|Gammaproteobacteria,1X4RF@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_213379_1	395495.Lcho_1367	0.000263	43.1	2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,2VX71@28216|Betaproteobacteria,1KM6Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	May protect the nitrogenase Fe-Mo protein from oxidative damage	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_213379_2	349124.Hhal_0277	1.25e-50	171.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,1S6X5@1236|Gammaproteobacteria,1WY5W@135613|Chromatiales	135613|Chromatiales	O	PFAM NifZ	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k59_120684_1	2340.JV46_15520	3.73e-192	540.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_228735_1	118161.KB235922_gene396	4.49e-16	77.4	COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_228735_2	1041139.KB902683_gene2761	1.32e-28	114.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_12205_1	1165841.SULAR_06413	1.18e-26	108.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2YN0J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_12205_2	1165841.SULAR_06408	7.23e-13	67.4	2ENEN@1|root,33G25@2|Bacteria,1NIJM@1224|Proteobacteria,42U7Y@68525|delta/epsilon subdivisions,2YPT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_81877_2	216591.BCAM0748	4.03e-05	46.2	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VV1V@28216|Betaproteobacteria,1KFBZ@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k59_58560_1	1165841.SULAR_06008	2.69e-09	60.5	COG4244@1|root,COG4244@2|Bacteria,1PJNV@1224|Proteobacteria,42TI9@68525|delta/epsilon subdivisions,2YQ43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_58560_2	1165841.SULAR_06003	8.03e-54	170.0	COG2863@1|root,COG2863@2|Bacteria,1PFA2@1224|Proteobacteria,42XJ8@68525|delta/epsilon subdivisions,2YQVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome c class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_120686_1	395493.BegalDRAFT_3344	9.04e-41	144.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,45ZTJ@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_190211_1	889378.Spiaf_1697	8.85e-06	51.6	COG0009@1|root,COG0009@2|Bacteria,2J73M@203691|Spirochaetes	203691|Spirochaetes	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
k59_221249_2	90813.JQMT01000001_gene481	9.12e-12	63.5	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,461EQ@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
k59_167177_1	357808.RoseRS_0444	2.03e-70	229.0	COG3385@1|root,COG3385@2|Bacteria,2G9A6@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_151331_1	1452718.JBOY01000137_gene1482	1.02e-104	332.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5067,P22_portal,Pkinase
k59_104895_1	247634.GPB2148_1004	8.01e-80	251.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4V4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	cbrB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k59_4748_1	1254432.SCE1572_13025	1.04e-20	94.7	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Metallophos
k59_112839_1	489825.LYNGBM3L_28080	1.3e-61	214.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
k59_128459_1	765913.ThidrDRAFT_2188	2.19e-131	412.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales	135613|Chromatiales	E	glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_190216_1	439235.Dalk_5087	3.66e-76	240.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_112841_1	1165841.SULAR_00710	7.84e-132	411.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_205666_1	1121385.AQXW01000004_gene1664	3.77e-08	58.5	COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria,2HBCJ@201174|Actinobacteria	201174|Actinobacteria	M	Zinc D-Ala-D-Ala carboxypeptidase	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
k59_213390_1	338963.Pcar_0592	9.36e-64	221.0	COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43RY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase A domain	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_50809_1	1049564.TevJSym_aa00360	2.41e-49	173.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1J6E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	involved in response to NO	nnrS	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
k59_128476_1	572477.Alvin_2831	1.97e-57	191.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_198163_1	1110502.TMO_1165	3.21e-28	108.0	COG1695@1|root,COG1695@2|Bacteria,1N33P@1224|Proteobacteria,2VER5@28211|Alphaproteobacteria,2JYHP@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
k59_112845_1	290315.Clim_0690	5.39e-23	98.6	COG0119@1|root,COG0119@2|Bacteria,1FD80@1090|Chlorobi	1090|Chlorobi	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_12231_2	1288826.MSNKSG1_17611	7.48e-33	123.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,464RI@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iSSON_1240.SSON_4131	Semialdhyde_dh,Semialdhyde_dhC
k59_136011_1	1161401.ASJA01000011_gene1501	3.68e-29	112.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2UDUB@28211|Alphaproteobacteria,43YPJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
k59_151351_1	1117318.PRUB_19964	5.17e-11	63.9	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,2Q2G0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	ATPase or kinase	yjeE	GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_221257_1	1056820.KB900640_gene295	5.5e-10	62.8	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria,2PQ65@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.25	ko:K08604	ko05110,ko05111,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PKD,Peptidase_M4,Peptidase_M4_C
k59_66391_2	1034943.BN1094_01443	6.37e-47	171.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1JDD0@118969|Legionellales	118969|Legionellales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_7,Response_reg
k59_159229_1	1041146.ATZB01000006_gene2522	8.42e-05	44.3	COG4118@1|root,COG4118@2|Bacteria,1NCQS@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_159229_2	96561.Dole_1902	5.22e-22	89.7	COG1848@1|root,COG1848@2|Bacteria,1N5DS@1224|Proteobacteria,43BCN@68525|delta/epsilon subdivisions,2X6RK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_97414_1	1165841.SULAR_09494	1.73e-135	396.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,42U1I@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	IV02_00930	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k59_228764_1	62928.azo3962	2.63e-23	99.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,2KUHY@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k59_27720_2	1042163.BRLA_c024600	6.87e-24	103.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K15654	ko01054,ko02024,map01054,map02024	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
k59_35642_1	999141.GME_15385	4.4e-34	119.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XKNG@135619|Oceanospirillales	135619|Oceanospirillales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_174608_1	56780.SYN_01181	1.34e-73	237.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MQY6@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	PFAM Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_4760_1	29760.VIT_00s1739g00010.t01	1.8e-77	233.0	2CDXT@1|root,2S1NU@2759|Eukaryota,37VRF@33090|Viridiplantae,3GJAF@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_236744_2	1123053.AUDG01000001_gene2318	8.07e-15	81.6	COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1X1I0@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein C	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
k59_236744_3	1042375.AFPL01000008_gene3259	5.24e-10	61.2	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,463YU@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_120719_1	1165841.SULAR_09214	1.53e-43	144.0	COG1585@1|root,COG1585@2|Bacteria,1QAJG@1224|Proteobacteria,43AB2@68525|delta/epsilon subdivisions,2YQRB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k59_120719_2	1165841.SULAR_09219	9.85e-157	445.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_244299_1	1121875.KB907551_gene1175	2.15e-189	535.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HZHR@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_120720_1	1165841.SULAR_00360	2.64e-83	260.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_50833_1	1168034.FH5T_09975	5.72e-36	138.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_104946_1	1168034.FH5T_11110	2.69e-103	312.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FW6G@200643|Bacteroidia	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
k59_97424_1	1319815.HMPREF0202_00784	8.15e-05	50.4	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,Phosphonate-bd
k59_35664_1	999541.bgla_2g01420	8.29e-10	59.7	COG2204@1|root,COG2207@1|root,COG2204@2|Bacteria,COG2207@2|Bacteria,1MYRK@1224|Proteobacteria,2W86U@28216|Betaproteobacteria,1K74G@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Sigma54_activ_2
k59_198606_2	449447.MAE_57700	1.54e-12	63.2	2BWKX@1|root,30VZR@2|Bacteria,1GG7S@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12612_1	395493.BegalDRAFT_2260	5.51e-09	65.5	COG1361@1|root,COG2373@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,Cadherin_3,Calx-beta,FecR,PKD,SdrD_B,TGFb_propeptide
k59_67037_1	395493.BegalDRAFT_2604	7.87e-91	279.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_190780_2	1158762.KB898037_gene2428	8.82e-25	100.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1WXWI@135613|Chromatiales	135613|Chromatiales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_89960_1	237609.PSAKL28_23600	1.46e-67	214.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	udp-glucose 4-epimerase	galE	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_59031_1	1279015.KB908464_gene2114	3.83e-54	189.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1Y3HG@135624|Aeromonadales	135624|Aeromonadales	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_59031_2	1448139.AI20_00225	8.33e-16	77.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1Y3WR@135624|Aeromonadales	135624|Aeromonadales	S	paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_82302_1	1165841.SULAR_05573	4.21e-142	421.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_20177_1	1165841.SULAR_00140	3.87e-127	367.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_244812_1	395493.BegalDRAFT_2192	5.11e-70	240.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,45ZUY@72273|Thiotrichales	72273|Thiotrichales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k59_128891_1	1165841.SULAR_04602	4.01e-65	206.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_32010_1	1379698.RBG1_1C00001G1092	1.97e-46	171.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
k59_8690_1	1163407.UU7_03597	1.46e-49	168.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1X47R@135614|Xanthomonadales	135614|Xanthomonadales	S	Zn-dependent hydrolases including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_225295_1	387093.SUN_1625	4.01e-66	214.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
k59_86053_1	439235.Dalk_0761	8.82e-57	194.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42PIH@68525|delta/epsilon subdivisions,2WJH2@28221|Deltaproteobacteria,2MIKZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_55161_1	765911.Thivi_4300	1.55e-56	196.0	COG5659@1|root,COG5659@2|Bacteria,1MXSV@1224|Proteobacteria,1SBWP@1236|Gammaproteobacteria,1WZ1F@135613|Chromatiales	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_186638_1	933262.AXAM01000010_gene1371	1.43e-126	372.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2MHR7@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_78287_1	1168034.FH5T_16570	6.44e-116	362.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_32016_1	118161.KB235922_gene3072	1.12e-72	234.0	COG3316@1|root,COG3316@2|Bacteria,1GHMB@1117|Cyanobacteria,3VNAF@52604|Pleurocapsales	2|Bacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k59_47389_1	1173027.Mic7113_4040	2.21e-36	141.0	COG0515@1|root,COG2114@1|root,COG2202@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,Guanylate_cyc,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
k59_101521_1	105559.Nwat_0122	8.44e-83	249.0	COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1S271@1236|Gammaproteobacteria,1X0PP@135613|Chromatiales	135613|Chromatiales	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
k59_24093_1	313596.RB2501_08575	2.67e-81	269.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
k59_194270_1	189753.AXAS01000003_gene4658	1.79e-24	101.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,3JQR6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
k59_171169_1	267608.RSp0228	7.6e-52	181.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2WH2X@28216|Betaproteobacteria,1KIHC@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Activator of aromatic catabolism	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k59_32023_1	997296.PB1_14674	5.18e-55	184.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,1ZC4G@1386|Bacillus	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_32023_2	720554.Clocl_2062	6e-16	72.8	COG1722@1|root,COG1722@2|Bacteria,1URN5@1239|Firmicutes,259IA@186801|Clostridia,3WMSC@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k59_240667_1	1268622.AVS7_02100	3.22e-27	115.0	COG3300@1|root,COG5002@1|root,COG3300@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,4AK5F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Bacterial signalling protein N terminal repeat	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_78299_2	1056820.KB900651_gene3146	1.21e-37	133.0	COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,1RSHR@1236|Gammaproteobacteria,2PPJQ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86061_2	375286.mma_1084	1.57e-137	408.0	COG0436@1|root,COG0436@2|Bacteria,1QE0D@1224|Proteobacteria,2VIUB@28216|Betaproteobacteria,473HZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Aminotransferase class I and II	asdA	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_117055_1	2340.JV46_16660	2.69e-81	255.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1J4FQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	major facilitator superfamily	yajR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_16362_1	1397528.Q671_16990	5.84e-105	310.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,1RY10@1236|Gammaproteobacteria,1XNMD@135619|Oceanospirillales	135619|Oceanospirillales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_33
k59_240670_1	1168034.FH5T_04005	9.09e-95	286.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_101533_1	580332.Slit_2507	1.36e-70	231.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,44V98@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_972_1	156578.ATW7_12408	0.000329	43.5	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
k59_171176_1	1094715.CM001373_gene1814	6.8e-51	182.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1JDMD@118969|Legionellales	118969|Legionellales	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
k59_93839_1	46234.ANA_C10985	2.26e-22	98.6	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HQSR@1161|Nostocales	1117|Cyanobacteria	Q	Nodulation protein S (NodS)	mcyA	-	-	ko:K16130	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,McyA_C,Methyltransf_12,PP-binding
k59_39717_1	247634.GPB2148_2931	5.09e-107	325.0	COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,1J7IF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	AbgT putative transporter family	abgT	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
k59_39717_2	1442599.JAAN01000031_gene1386	3.06e-28	112.0	COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,1RS2Q@1236|Gammaproteobacteria,1X3UN@135614|Xanthomonadales	135614|Xanthomonadales	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
k59_147881_1	136993.KB900626_gene3028	1.01e-24	97.1	COG4634@1|root,COG4634@2|Bacteria,1N9QC@1224|Proteobacteria,2UISH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
k59_140327_1	485915.Dret_2002	5.99e-95	289.0	COG3464@1|root,COG3464@2|Bacteria,1R4DH@1224|Proteobacteria,43AQ4@68525|delta/epsilon subdivisions,2X63W@28221|Deltaproteobacteria,2MGXP@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
k59_178934_1	395493.BegalDRAFT_3339	8.72e-31	120.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,45ZQB@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_47415_1	323848.Nmul_A0050	1.14e-63	216.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,372JH@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_55497_1	118161.KB235922_gene2608	3.82e-146	426.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1G21B@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_233537_1	1121405.dsmv_1665	2.04e-85	265.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2MMPY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
k59_163790_1	10689.H9C0C7_BPCPT	2.87e-24	105.0	4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses  no RNA stage,4QPTC@28883|Caudovirales,4QJW3@10662|Myoviridae	10662|Myoviridae	S	Pfam:Terminase_6C	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63193_1	765910.MARPU_11355	3.61e-56	189.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1WX7X@135613|Chromatiales	135613|Chromatiales	J	SAM-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_155981_1	1187848.AJYQ01000003_gene410	6.97e-122	363.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_47770_1	1395516.PMO01_09230	1.01e-33	135.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_179318_1	3702.ATMG01275.1	3.58e-76	235.0	COG1005@1|root,KOG4770@2759|Eukaryota,37V23@33090|Viridiplantae,3GIN5@35493|Streptophyta,3I0WR@3699|Brassicales	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)	nad1	GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114	1.6.5.3	ko:K03878	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_125119_1	290397.Adeh_2037	7.32e-19	93.6	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,2YUDK@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_132818_1	765911.Thivi_3691	2.09e-25	109.0	COG0642@1|root,COG1225@1|root,COG1225@2|Bacteria,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1WXM4@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_47776_1	595460.RRSWK_04700	8.3e-109	328.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_32526_2	4565.Traes_2AL_D57A37D6C.1	1.44e-107	315.0	COG2801@1|root,KOG0017@2759|Eukaryota,37TAQ@33090|Viridiplantae,3GDDG@35493|Streptophyta,3M2YP@4447|Liliopsida	35493|Streptophyta	L	cellular component organization	ccmFc	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	CcmF_C
k59_70887_1	268746.Q58MM0_BPPRM	1.69e-20	94.0	4QHPV@10239|Viruses,4QWVT@35237|dsDNA viruses  no RNA stage,4QTVP@28883|Caudovirales,4QICC@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_24465_1	1165841.SULAR_08127	1.32e-124	369.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_241047_1	768671.ThimaDRAFT_3082	6.16e-10	61.2	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_241047_2	563040.Saut_0085	3.27e-46	159.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,42PDX@68525|delta/epsilon subdivisions,2YR54@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_179329_1	1168034.FH5T_17460	9.11e-64	196.0	2DB76@1|root,2Z7JZ@2|Bacteria,4NQDC@976|Bacteroidetes,2FSRT@200643|Bacteroidia	976|Bacteroidetes	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k59_179329_2	1168034.FH5T_17455	4.43e-51	173.0	COG3497@1|root,COG3497@2|Bacteria,4NEKK@976|Bacteroidetes,2FP61@200643|Bacteroidia	976|Bacteroidetes	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_9190_1	565045.NOR51B_2733	1e-25	106.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,1JBU7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	CR COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_202476_1	1353529.M899_0004	4.99e-35	139.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2MSUN@213481|Bdellovibrionales,2WJ9X@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_155983_1	1336243.JAEA01000006_gene350	8.53e-11	63.9	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the peptidase M48B family	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_70893_2	1121875.KB907549_gene1945	6.92e-42	143.0	COG4149@1|root,COG4149@2|Bacteria,4NIXK@976|Bacteroidetes,1I0Y9@117743|Flavobacteriia	976|Bacteroidetes	P	Molybdate ABC transporter permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_1355_3	2340.JV46_15720	2.63e-89	270.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1J54C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
k59_148252_1	7668.SPU_026882-tr	0.000234	44.7	COG2192@1|root,2RKTV@2759|Eukaryota,3A7C0@33154|Opisthokonta,3BU3I@33208|Metazoa,3DICE@33213|Bilateria	33208|Metazoa	O	Carbamoyltransferase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_148252_3	316067.Geob_3189	1.92e-68	229.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,42TBM@68525|delta/epsilon subdivisions,2WP92@28221|Deltaproteobacteria,43V6A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
k59_218028_1	765913.ThidrDRAFT_0031	6.02e-26	103.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1WW3I@135613|Chromatiales	135613|Chromatiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_218028_2	870187.Thini_4414	2.14e-61	199.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_132827_1	999541.bgla_2g21880	4.43e-71	229.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,1K0NF@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the mannose-6-phosphate isomerase type 2 family	algA	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_125137_1	706587.Desti_1914	1.8e-109	325.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MR3T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_148260_1	1122619.KB892285_gene698	0.000469	42.4	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,3T2D6@506|Alcaligenaceae	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_148260_2	998674.ATTE01000001_gene674	1.68e-48	167.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,46052@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_94257_1	1449350.OCH239_03905	2.96e-26	105.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_94257_2	459495.SPLC1_S040120	7.8e-07	54.7	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G06Q@1117|Cyanobacteria,1HA2E@1150|Oscillatoriales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_Tnp_IS630
k59_186983_1	1304888.ATWF01000001_gene1031	2.28e-27	109.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_136086_1	395493.BegalDRAFT_3250	3.54e-110	327.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,45ZQQ@72273|Thiotrichales	72273|Thiotrichales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_81946_1	493475.GARC_5300	2.34e-91	293.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,46942@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_236769_1	207954.MED92_11069	1.82e-72	222.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5U@1224|Proteobacteria,1SAZE@1236|Gammaproteobacteria,1XPKV@135619|Oceanospirillales	135619|Oceanospirillales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136089_1	502025.Hoch_0085	8.01e-27	114.0	COG0492@1|root,COG1146@1|root,COG3266@1|root,COG0492@2|Bacteria,COG1146@2|Bacteria,COG3266@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
k59_174662_1	56107.Cylst_3835	6.06e-05	51.2	COG1166@1|root,COG1166@2|Bacteria,1G1C4@1117|Cyanobacteria,1HIE3@1161|Nostocales	1117|Cyanobacteria	E	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
k59_151408_1	1168034.FH5T_04840	8.19e-19	85.5	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,2FNND@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_151408_2	1168034.FH5T_04835	2.96e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,2FTV5@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_236775_1	1137799.GZ78_27125	3.4e-30	120.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XHFB@135619|Oceanospirillales	135619|Oceanospirillales	M	Lipoprotein releasing system, transmembrane protein	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_182638_1	1168034.FH5T_05075	3.37e-116	344.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,2FNCN@200643|Bacteroidia	976|Bacteroidetes	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_74213_1	583355.Caka_2195	5.91e-115	343.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_174668_2	1121405.dsmv_2750	2.95e-30	119.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MIZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Starch synthase catalytic	-	-	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176	ko00500,ko01100,ko01110,ko02026,ko04973,map00500,map01100,map01110,map02026,map04973	M00565	R02108,R02112,R02421,R11262	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GH13,GT5	-	Glyco_trans_1_4,Glyco_transf_5,Glycos_transf_1
k59_190281_1	745014.OMB55_00022080	2.79e-21	92.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0282,ic_1306.c0493	F420_oxidored,P5CR_dimer
k59_190281_2	301.JNHE01000041_gene3167	6.28e-18	80.5	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1YD2V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	YGGT family	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_19813_1	1165096.ARWF01000001_gene2278	8.65e-64	220.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KKQX@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_120752_2	583355.Caka_2804	1.93e-23	97.1	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,3K7JX@414999|Opitutae	414999|Opitutae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_104989_1	1168034.FH5T_11625	3.43e-30	114.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_104989_2	926559.JoomaDRAFT_2234	1.17e-13	71.2	COG1395@1|root,COG1395@2|Bacteria,4PKFZ@976|Bacteroidetes	976|Bacteroidetes	K	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
k59_159312_1	68170.KL590531_gene10122	8.1e-08	58.9	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4E21F@85010|Pseudonocardiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_112937_1	1165841.SULAR_02758	2.25e-115	335.0	COG2048@1|root,COG2048@2|Bacteria,1RFWK@1224|Proteobacteria,43B86@68525|delta/epsilon subdivisions,2YT6P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Heterodisulfide reductase subunit B	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
k59_12740_1	292415.Tbd_0245	9.21e-97	288.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria	1224|Proteobacteria	V	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98044_1	570952.ATVH01000019_gene727	4.22e-89	278.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,2JW2Q@204441|Rhodospirillales	204441|Rhodospirillales	C	ATP ADP translocase	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_144878_1	1134912.AJTV01000015_gene378	2.83e-37	138.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	eutR	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009438,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019172,GO:0019243,GO:0019249,GO:0019438,GO:0019752,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042180,GO:0042182,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0046483,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901617	-	ko:K04033	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
k59_20307_1	439235.Dalk_2155	9.86e-23	102.0	COG2931@1|root,COG2931@2|Bacteria,1R094@1224|Proteobacteria	1224|Proteobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_144880_1	756067.MicvaDRAFT_4927	1.32e-37	144.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_51487_1	2340.JV46_23890	2.06e-86	260.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1J4XA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1137 ABC-type (unclassified) transport system, ATPase component	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_82428_1	395493.BegalDRAFT_1988	7.81e-33	119.0	28NH4@1|root,2ZBJ2@2|Bacteria,1RADQ@1224|Proteobacteria,1S3GR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82428_2	1163389.OOM_0056	6.23e-34	124.0	COG2179@1|root,COG2179@2|Bacteria,1N059@1224|Proteobacteria,1SART@1236|Gammaproteobacteria,4613K@72273|Thiotrichales	72273|Thiotrichales	S	Mitochondrial PGP phosphatase	-	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	PGP_phosphatase
k59_51489_1	1279019.ARQK01000057_gene809	5.72e-86	262.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1WW4K@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_121535_1	1121937.AUHJ01000007_gene1914	4.08e-86	264.0	COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria,468CF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase
k59_198838_2	153721.MYP_3958	2.17e-56	179.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_214055_1	387093.SUN_0014	1.3e-103	314.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_152117_1	313596.RB2501_16014	1.82e-137	394.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1HWJN@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
k59_136557_1	1123392.AQWL01000013_gene2375	9.54e-147	419.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_152123_1	1123508.JH636441_gene3643	8.42e-09	62.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
k59_36308_1	1232437.KL661994_gene354	1.15e-98	298.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria,2MKFC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_59278_1	1415755.JQLV01000001_gene1214	1.09e-05	50.8	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XHZK@135619|Oceanospirillales	135619|Oceanospirillales	U	Type II and III secretion system protein	pilQ	-	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_59278_2	697282.Mettu_1087	1.51e-28	110.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1XF5W@135618|Methylococcales	135618|Methylococcales	NU	PFAM Pilus assembly protein PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_28324_1	1165841.SULAR_01435	2.82e-98	302.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,43B1H@68525|delta/epsilon subdivisions,2YT54@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_144899_1	1297570.MESS4_320073	6.36e-11	62.4	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2UTVN@28211|Alphaproteobacteria,43MAU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_237347_1	714943.Mucpa_2531	8.17e-73	243.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_136569_1	1250232.JQNJ01000001_gene1580	4.46e-51	182.0	COG3118@1|root,COG3118@2|Bacteria,4PND9@976|Bacteroidetes,1IKUJ@117743|Flavobacteriia	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_221780_1	1168034.FH5T_08740	3.18e-152	447.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,4NKCK@976|Bacteroidetes,2G172@200643|Bacteroidia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,TPR_16,TPR_19,TPR_8
k59_198848_1	448385.sce5671	1.25e-29	109.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_98058_1	439375.Oant_1111	2.62e-116	342.0	COG3938@1|root,COG3938@2|Bacteria,1NVF9@1224|Proteobacteria,2TX8Z@28211|Alphaproteobacteria,1J1YQ@118882|Brucellaceae	28211|Alphaproteobacteria	G	4-hydroxyproline epimerase activity	-	GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006579,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0036361,GO:0042219,GO:0044237,GO:0044248,GO:0044270,GO:0047580,GO:0047661,GO:0071704,GO:1901564,GO:1901565,GO:1901575	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k59_244966_1	4565.EPlTAEP00000010095	9.86e-12	65.9	2EVD3@1|root,2SXD4@2759|Eukaryota,389WW@33090|Viridiplantae,3GYZ4@35493|Streptophyta,3M92P@4447|Liliopsida,3ISTD@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175152_1	395493.BegalDRAFT_3469	2.74e-47	167.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87,TPR_2,TPR_8
k59_67220_1	398512.JQKC01000024_gene3213	2.83e-36	139.0	COG2984@1|root,COG2984@2|Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_105528_1	522306.CAP2UW1_0207	2.64e-12	70.1	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
k59_190940_1	498211.CJA_1704	1.79e-38	143.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1FFRK@10|Cellvibrio	1236|Gammaproteobacteria	T	Flagellar regulatory protein FleQ	fleQ	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
k59_74825_1	1121396.KB893077_gene741	3.05e-101	308.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42YYU@68525|delta/epsilon subdivisions,2WU8G@28221|Deltaproteobacteria,2MN6U@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pfam:DUF377	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_105532_2	1049564.TevJSym_aw00370	3.63e-39	133.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,1JAXW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur oxidation protein SoxZ	soxZ	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_36335_1	313596.RB2501_09325	3.04e-82	264.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
k59_136580_1	1165841.SULAR_03262	1.41e-191	541.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_136580_2	102107.XP_008225561.1	1.56e-05	50.1	COG0531@1|root,KOG1286@2759|Eukaryota,37JF4@33090|Viridiplantae,3GFI1@35493|Streptophyta,4JMH1@91835|fabids	35493|Streptophyta	E	cationic amino acid transporter	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
k59_59300_1	1121374.KB891575_gene1200	1.07e-101	310.0	COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,1RP1J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
k59_237357_1	933262.AXAM01000028_gene3317	1.55e-40	150.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_190944_1	87626.PTD2_21447	2.72e-14	72.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,2Q0IG@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365	Ketoacyl-synt_C,ketoacyl-synt
k59_190944_2	1121013.P873_07135	1.49e-33	117.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1X7EF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_190944_3	2340.JV46_14770	3.01e-105	308.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1J4H7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710	adh_short_C2
k59_129035_1	694427.Palpr_0876	1.8e-48	159.0	2E2RH@1|root,32XTZ@2|Bacteria,4NTV2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129035_2	694427.Palpr_0877	1.05e-16	75.9	2ER3W@1|root,33IPG@2|Bacteria,4NYM0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_183208_1	316056.RPC_3027	7.24e-57	192.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,2TRM3@28211|Alphaproteobacteria,3JRE2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_51506_1	1410620.SHLA_2c000080	2.67e-07	52.8	COG1802@1|root,COG1802@2|Bacteria,1R8F8@1224|Proteobacteria,2U4DD@28211|Alphaproteobacteria,4BD47@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_51506_2	1502724.FF80_02067	4.21e-33	124.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2TTWT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	3.5.4.22	ko:K21062	ko00330,map00330	-	R02280	RC00679	ko00000,ko00001,ko01000	-	-	-	DHDPS
k59_113484_1	671143.DAMO_1656	4.77e-08	55.8	COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria	2|Bacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
k59_113484_2	1121920.AUAU01000024_gene2352	3.96e-40	145.0	COG1190@1|root,COG1190@2|Bacteria,3Y3N0@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_12770_1	1123242.JH636435_gene3010	5.76e-40	144.0	COG0540@1|root,COG0540@2|Bacteria,2IXJB@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_221804_1	289376.THEYE_A1395	1.12e-36	135.0	COG4974@1|root,COG4974@2|Bacteria,3J0PS@40117|Nitrospirae	40117|Nitrospirae	L	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_113487_1	983545.Glaag_2007	2.15e-78	249.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,463Y3@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
k59_20349_1	1255043.TVNIR_0911	6.83e-115	344.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1WYPQ@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_229340_1	631362.Thi970DRAFT_00046	5.94e-36	138.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1S7R5@1236|Gammaproteobacteria,1X0KN@135613|Chromatiales	135613|Chromatiales	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_206226_1	1165841.SULAR_04828	4.59e-100	307.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2YMUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_175179_1	1165841.SULAR_06448	5.51e-75	246.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_28351_1	1318628.MARLIPOL_16164	4.81e-31	122.0	COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46511@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	1.3.1.12,1.3.1.43,2.5.1.19	ko:K00210,ko:K00220,ko:K00800	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00022,M00025,M00040	R00732,R01728,R03460	RC00125,RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase,PDH
k59_193952_2	1129374.AJE_11659	1.68e-86	284.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,464KJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
k59_132085_1	870187.Thini_0575	6.1e-20	96.3	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,461UU@72273|Thiotrichales	72273|Thiotrichales	Q	PFAM mce related protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_224946_1	706587.Desti_0887	2.93e-14	68.6	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_224946_2	1265505.ATUG01000002_gene2705	4.02e-74	225.0	COG5423@1|root,COG5423@2|Bacteria	2|Bacteria	M	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
k59_193953_2	32057.KB217478_gene5388	6.43e-58	187.0	COG4636@1|root,COG4636@2|Bacteria,1G4MT@1117|Cyanobacteria,1HMD8@1161|Nostocales	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_596_1	104623.Ser39006_02426	1.01e-19	87.4	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,400WH@613|Serratia	1236|Gammaproteobacteria	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSFV_1184.SFV_1868	GAD,tRNA-synt_2,tRNA_anti-codon
k59_124299_1	998674.ATTE01000001_gene2298	2.32e-94	298.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,46059@72273|Thiotrichales	72273|Thiotrichales	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_116681_1	1187848.AJYQ01000036_gene2746	1.05e-81	259.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGC@1236|Gammaproteobacteria,1Y0A3@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_155359_2	1049564.TevJSym_ab01480	5.97e-96	290.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1J4EX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_186297_1	1165841.SULAR_05943	3.38e-25	104.0	COG2849@1|root,COG2849@2|Bacteria,1MZCG@1224|Proteobacteria,42XCP@68525|delta/epsilon subdivisions,2YQ7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
k59_217321_1	665942.HMPREF1022_02129	7.52e-47	155.0	COG1943@1|root,COG1943@2|Bacteria,1N5A2@1224|Proteobacteria,43BHG@68525|delta/epsilon subdivisions,2X6VT@28221|Deltaproteobacteria,2MBYP@213115|Desulfovibrionales	1224|Proteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_8366_1	382464.ABSI01000010_gene3321	1.05e-11	75.5	COG2706@1|root,COG3210@1|root,COG4733@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
k59_124316_1	472759.Nhal_2840	5.47e-43	154.0	COG4006@1|root,COG4006@2|Bacteria,1RFA6@1224|Proteobacteria,1S6RM@1236|Gammaproteobacteria,1WZKF@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1887)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1887
k59_163486_1	760192.Halhy_2051	5.39e-40	154.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	4.6.1.1	ko:K01768,ko:K16923,ko:K19694	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00582,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.28	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_93909_1	1279009.ADICEAN_03078	5.02e-155	452.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47P0R@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
k59_109340_1	1165841.SULAR_05468	2.01e-94	286.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2YMGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_78421_1	748247.AZKH_3122	1.73e-61	206.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,2KUXQ@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_39771_1	2340.JV46_09630	3.67e-207	580.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_39771_2	765911.Thivi_4247	3.38e-22	95.1	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1SB6M@1236|Gammaproteobacteria,1X0V1@135613|Chromatiales	135613|Chromatiales	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_70582_1	1165841.SULAR_00270	7.01e-108	318.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2YN18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_24157_1	933262.AXAM01000047_gene2340	5.53e-101	302.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,42MFN@68525|delta/epsilon subdivisions,2WIJE@28221|Deltaproteobacteria,2MIKH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rmlB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_1038_1	631362.Thi970DRAFT_03592	5.4e-34	130.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1WWWJ@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_186713_2	1165841.SULAR_09934	2.16e-126	370.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_117159_1	998674.ATTE01000001_gene2025	4.74e-50	168.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,4602Y@72273|Thiotrichales	72273|Thiotrichales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_117159_2	2340.JV46_28010	4.94e-39	142.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1JC0J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_39779_1	768671.ThimaDRAFT_1939	4.53e-124	367.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,1T5B6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_225388_1	439235.Dalk_1518	1.43e-82	257.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,42MNG@68525|delta/epsilon subdivisions,2WIWX@28221|Deltaproteobacteria,2MII6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_8837_1	525909.Afer_2015	5.06e-21	85.5	COG2963@1|root,COG2963@2|Bacteria,2IMG6@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_8837_2	1121028.ARQE01000016_gene2619	4.79e-92	282.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2PK0U@255475|Aurantimonadaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_39784_1	987059.RBXJA2T_13164	6.79e-07	50.4	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,1KJ91@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etf	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
k59_39784_2	78245.Xaut_0474	1.75e-23	101.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,3EY9C@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	AFG1-like ATPase	zapE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
k59_178983_1	387093.SUN_1823	3.03e-120	358.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2YMQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_70596_1	2340.JV46_15320	6.38e-102	306.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	pyridine nucleotide-disulphide oxidoreductase	sqr	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_171264_1	1168034.FH5T_07565	7.94e-89	271.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,2FM9Q@200643|Bacteroidia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_101581_1	572480.Arnit_0213	2.91e-25	100.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2YM7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
k59_202218_1	1565129.JSFF01000003_gene2098	1.66e-06	54.7	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,2Q9PH@267890|Shewanellaceae	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,AAA_30,UvrD_C_2
k59_240770_1	1123059.KB823013_gene502	3.63e-59	206.0	COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
k59_178987_1	1191299.AJYX01000098_gene560	5.11e-32	129.0	COG4935@1|root,COG4935@2|Bacteria,1RCIN@1224|Proteobacteria,1S3H9@1236|Gammaproteobacteria,1XUZF@135623|Vibrionales	135623|Vibrionales	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_M36
k59_171285_1	1122134.KB893650_gene1119	3.52e-27	100.0	COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,1SCI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3
k59_109370_1	69395.JQLZ01000003_gene138	6.73e-64	208.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2TUX1@28211|Alphaproteobacteria,2KHKJ@204458|Caulobacterales	204458|Caulobacterales	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k59_109370_2	290315.Clim_0110	5.47e-32	115.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
k59_178993_1	887898.HMPREF0551_2517	1.52e-13	68.6	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,1K026@119060|Burkholderiaceae	28216|Betaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_178993_2	563192.HMPREF0179_02879	1.7e-24	99.8	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2M93X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_8854_1	1165841.SULAR_08502	1.59e-19	85.5	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	iscU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_140367_1	1123237.Salmuc_03905	5.79e-35	124.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2U6JA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_16455_1	1165841.SULAR_05863	1.17e-22	92.8	2DHTH@1|root,300W4@2|Bacteria,1Q6H4@1224|Proteobacteria,432SW@68525|delta/epsilon subdivisions,2YSX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_8857_1	335543.Sfum_1617	2.18e-40	151.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_171305_1	1165841.SULAR_00220	6.44e-70	217.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,42SHJ@68525|delta/epsilon subdivisions,2YPQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin,Thioredoxin_8
k59_171305_2	1165841.SULAR_00215	5.09e-30	113.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2YMT4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_86160_1	211586.SO_3321	3.4e-86	268.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,1SZQR@1236|Gammaproteobacteria,2QEAJ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_93953_1	1219031.BBJR01000041_gene2937	5.4e-05	44.7	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,4ACM2@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
k59_93953_2	1173027.Mic7113_5879	1.85e-11	68.2	COG0683@1|root,COG0683@2|Bacteria,1GBR6@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peptidase_C14,Peripla_BP_6
k59_24196_1	565045.NOR51B_2646	1.33e-142	414.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1J88Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_132497_1	701347.Entcl_0653	8.66e-32	124.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,3X0YE@547|Enterobacter	1236|Gammaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k59_55243_1	313603.FB2170_08949	2.27e-104	309.0	COG3439@1|root,COG3439@2|Bacteria,4NH52@976|Bacteroidetes,1I16N@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109378_1	1168034.FH5T_01455	1.72e-44	150.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,4NHF0@976|Bacteroidetes,2FUN6@200643|Bacteroidia	976|Bacteroidetes	C	rubredoxin	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_55244_1	1121937.AUHJ01000002_gene3434	1.35e-25	103.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,46AVD@72275|Alteromonadaceae	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_55244_2	1218352.B597_016405	1.08e-25	101.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1RQ26@1236|Gammaproteobacteria,1Z2MB@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	attM	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_132500_1	1120965.AUBV01000012_gene1410	2.75e-20	92.8	COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,47Y41@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_217778_1	45406.Q06ER8_BPR32	2.29e-44	158.0	4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses  no RNA stage,4QPEB@28883|Caudovirales,4QHXI@10662|Myoviridae	10662|Myoviridae	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_217778_2	349123.Lreu23DRAFT_3398	8.14e-12	63.2	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_70619_1	1168034.FH5T_14470	3.62e-87	270.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,2FP4N@200643|Bacteroidia	976|Bacteroidetes	O	serine protease	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,Peptidase_S49,SDH_sah
k59_47538_2	1165841.SULAR_06033	2.56e-33	122.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_8871_1	1033802.SSPSH_002338	1.12e-109	345.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
k59_8873_1	504472.Slin_2921	5.53e-11	67.0	COG2120@1|root,COG2120@2|Bacteria,4NP5K@976|Bacteroidetes,47PVJ@768503|Cytophagia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	NodS,PIG-L
k59_32225_1	864702.OsccyDRAFT_2068	5.12e-12	73.2	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1G0DN@1117|Cyanobacteria,1HA78@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
k59_233298_1	349521.HCH_06655	8.51e-56	181.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,1XIAQ@135619|Oceanospirillales	135619|Oceanospirillales	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
k59_65911_2	1165841.SULAR_10454	1.45e-40	134.0	COG1977@1|root,COG1977@2|Bacteria,1Q2EI@1224|Proteobacteria,42VIE@68525|delta/epsilon subdivisions,2YQ69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin converting factor	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_65911_3	1165841.SULAR_10459	2.75e-28	107.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42MJZ@68525|delta/epsilon subdivisions,2YN8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_166706_1	1163617.SCD_n01730	4.16e-111	341.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJI0@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA_2
k59_58081_1	387093.SUN_2352	3.25e-77	232.0	COG2259@1|root,COG2259@2|Bacteria,1RKEE@1224|Proteobacteria,42SF5@68525|delta/epsilon subdivisions,2YPGK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_135507_1	765913.ThidrDRAFT_2740	1.79e-29	119.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WXP6@135613|Chromatiales	135613|Chromatiales	O	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_73617_1	393595.ABO_0317	3.7e-29	112.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XHDH@135619|Oceanospirillales	135619|Oceanospirillales	F	carbamoyl-phosphate synthetase glutamine chain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_73617_2	290398.Csal_3093	3.64e-14	72.4	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1XH4T@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_58418_2	1379698.RBG1_1C00001G1531	2.28e-89	276.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_35473_1	240016.ABIZ01000001_gene1936	4.94e-62	207.0	COG0152@1|root,COG0152@2|Bacteria	2|Bacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_174481_1	631362.Thi970DRAFT_02376	6.51e-28	109.0	COG2863@1|root,COG2863@2|Bacteria,1R8K9@1224|Proteobacteria,1S1Q4@1236|Gammaproteobacteria,1WXXK@135613|Chromatiales	135613|Chromatiales	C	PFAM Cytochrome C	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrome_CBB3
k59_89385_1	1249480.B649_00030	2.2e-18	88.6	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_50694_2	946077.W5A_02595	5.01e-75	231.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1HX2F@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_97238_1	1165841.SULAR_04132	2.6e-61	196.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_97238_2	1165841.SULAR_04127	6.5e-115	334.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2YM9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_213261_1	1408473.JHXO01000010_gene3573	2.07e-62	194.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia	976|Bacteroidetes	FG	Histidine triad domain protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_43076_1	686578.AFFX01000001_gene1411	3.08e-70	225.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,1S3FP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_182470_1	1165841.SULAR_06048	2.18e-15	75.1	COG1477@1|root,COG1477@2|Bacteria,1PFA4@1224|Proteobacteria,42S5P@68525|delta/epsilon subdivisions,2YPB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_182470_2	1165841.SULAR_06043	1.75e-66	219.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_198025_1	1198232.CYCME_0850	3.91e-43	151.0	28KDQ@1|root,2ZA05@2|Bacteria,1QE8C@1224|Proteobacteria,1S0JF@1236|Gammaproteobacteria,462VG@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213263_1	1304880.JAGB01000001_gene231	3.93e-36	135.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k59_174487_1	1219077.VAZ01S_133_00020	9.08e-18	83.2	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Lysophospholipase	ynbC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Methyltransf_20
k59_120561_1	251229.Chro_5369	3.79e-34	134.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G3J0@1117|Cyanobacteria,3VM91@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k59_174488_1	1123320.KB889741_gene5333	6.89e-30	123.0	COG1020@1|root,COG3208@1|root,COG1020@2|Bacteria,COG3208@2|Bacteria	2|Bacteria	Q	Thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,MFS_1,PP-binding,Thioesterase
k59_66272_1	998674.ATTE01000001_gene2400	8.48e-24	105.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,460BC@72273|Thiotrichales	72273|Thiotrichales	Q	transporter, dctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_190098_1	388413.ALPR1_13065	2.97e-15	79.7	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,47JPM@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
k59_81797_1	1165841.SULAR_08252	6.86e-62	196.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_81797_2	1165841.SULAR_08257	8.31e-119	355.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
k59_128367_1	1121920.AUAU01000007_gene519	7.58e-93	297.0	COG0187@1|root,COG0187@2|Bacteria,3Y369@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_27574_2	1085623.GNIT_2363	6.91e-13	71.2	COG1317@1|root,COG1317@2|Bacteria,1QD77@1224|Proteobacteria,1S7CU@1236|Gammaproteobacteria,464H9@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	Flagellar biosynthesis type III secretory pathway protein	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH,Yae1_N
k59_190100_1	1168034.FH5T_11890	5.92e-117	347.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,2FM8E@200643|Bacteroidia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_128368_1	1565129.JSFF01000023_gene2808	1.86e-25	103.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,2QAQJ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Competence protein	gntX	GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_174498_1	104623.Ser39006_02890	2.14e-43	154.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,404F7@613|Serratia	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
k59_236593_1	342610.Patl_1818	3.78e-45	164.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,2PZQJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_167115_1	313596.RB2501_11037	7.88e-108	331.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_174503_1	1192034.CAP_4377	4.55e-39	152.0	COG3321@1|root,COG4221@1|root,COG3321@2|Bacteria,COG4221@2|Bacteria,1PXKK@1224|Proteobacteria,430EF@68525|delta/epsilon subdivisions,2WVY2@28221|Deltaproteobacteria,2YWBP@29|Myxococcales	28221|Deltaproteobacteria	Q	polyketide synthase	-	-	-	ko:K13614	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_120590_2	2340.JV46_21930	1.35e-57	180.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_120590_3	1249627.D779_0034	1.03e-99	298.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,1S0ZZ@1236|Gammaproteobacteria,1WX12@135613|Chromatiales	135613|Chromatiales	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9,Response_reg
k59_89408_1	435908.IDSA_03195	2.65e-67	218.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,2QFCG@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_143831_1	1165841.SULAR_10189	3.18e-24	95.1	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42RJW@68525|delta/epsilon subdivisions,2YP85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_143831_2	1165841.SULAR_10194	1.5e-46	150.0	2AJEY@1|root,31A0Z@2|Bacteria,1Q4KX@1224|Proteobacteria,4325F@68525|delta/epsilon subdivisions,2YSRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_143831_3	1165841.SULAR_10199	3.73e-60	191.0	COG1028@1|root,COG1028@2|Bacteria,1RFQT@1224|Proteobacteria,43D9I@68525|delta/epsilon subdivisions,2YP3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.320	ko:K16216	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
k59_159145_1	1165841.SULAR_04427	1.39e-94	277.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2YPNW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetyltransferase	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_228681_1	1121875.KB907546_gene2199	2.12e-59	200.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_151269_1	886293.Sinac_1231	4.49e-48	171.0	COG3464@1|root,COG3464@2|Bacteria,2J4EX@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_4662_1	1122194.AUHU01000002_gene2904	6.11e-37	133.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,465V4@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	wzt	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran,Wzt_C
k59_128379_1	420662.Mpe_A2703	9.62e-29	115.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,1KKAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_27580_1	1265505.ATUG01000002_gene1005	6.42e-126	371.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,2MIP5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM PhoH-like protein	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_174521_1	1080067.BAZH01000003_gene3670	1.26e-07	54.3	COG3454@1|root,COG3454@2|Bacteria,1MV7H@1224|Proteobacteria,1RMR7@1236|Gammaproteobacteria,3WVCT@544|Citrobacter	1236|Gammaproteobacteria	P	Amidohydrolase family	phnM	GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0044237,GO:0046434,GO:0071704,GO:1901575	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_174521_2	351016.RAZWK3B_09331	2.46e-32	124.0	COG3709@1|root,COG3709@2|Bacteria,1RK3Z@1224|Proteobacteria,2U616@28211|Alphaproteobacteria,2P316@2433|Roseobacter	28211|Alphaproteobacteria	P	Protein of unknown function (DUF1045)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1045
k59_143843_1	395493.BegalDRAFT_1842	3.98e-78	241.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,460XT@72273|Thiotrichales	72273|Thiotrichales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_81810_1	460265.Mnod_3938	9.02e-50	176.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,1JWWY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_81812_1	1121396.KB893100_gene4312	1.36e-65	211.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,2MI1V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k59_205574_1	1000565.METUNv1_03496	1.62e-16	79.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,2KW06@206389|Rhodocyclales	206389|Rhodocyclales	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_205574_2	395495.Lcho_0067	9.35e-45	160.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KNAW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_182492_1	1049564.TevJSym_as00020	4.22e-71	230.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1J4JE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
k59_120606_1	2340.JV46_05960	3.14e-102	323.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
k59_135914_1	497321.C664_15458	3.61e-60	193.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2VQQ0@28216|Betaproteobacteria,2KW85@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_27596_1	1168034.FH5T_15545	1.14e-117	358.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,2FMEB@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_97286_1	1245471.PCA10_29460	2.93e-78	250.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD6	-	6.2.1.48	ko:K00666,ko:K02182,ko:K13776	ko00281,map00281	-	R08088	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_74029_1	1220534.B655_0880	2.24e-73	226.0	COG1898@1|root,arCOG04188@2157|Archaea	2157|Archaea	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_159162_1	1165841.SULAR_09924	1.81e-151	431.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2YM8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_66298_1	765420.OSCT_2506	9.65e-17	86.3	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,376YF@32061|Chloroflexia	32061|Chloroflexia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_12139_2	1506716.A0A076G713_9CAUD	4.49e-18	80.5	4QSR9@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159165_1	398512.JQKC01000001_gene2398	8.68e-84	266.0	28I0T@1|root,2Z85H@2|Bacteria,1TQRJ@1239|Firmicutes,247Z4@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4914
k59_217125_1	573061.Clocel_0941	2.46e-09	64.3	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,NUDIX,PqqD,Radical_SAM,SPASM
k59_85555_1	1121374.KB891576_gene329	3.18e-11	60.8	COG0545@1|root,COG0545@2|Bacteria,1RCWV@1224|Proteobacteria,1S7UP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C,FKBP_N
k59_85555_2	644107.SL1157_3311	1.46e-64	210.0	COG0679@1|root,COG0679@2|Bacteria,1MY23@1224|Proteobacteria,2TR4M@28211|Alphaproteobacteria,4NAJS@97050|Ruegeria	28211|Alphaproteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_93374_1	1004149.AFOE01000059_gene290	5.14e-49	166.0	COG0463@1|root,COG0463@2|Bacteria,4NM6V@976|Bacteroidetes,1I1EQ@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_64,Glycos_transf_2
k59_46843_1	395493.BegalDRAFT_2969	1.19e-67	234.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_77796_1	1297742.A176_05124	1.01e-05	53.9	COG0705@1|root,COG3118@1|root,COG0705@2|Bacteria,COG3118@2|Bacteria,1PBY3@1224|Proteobacteria,435B3@68525|delta/epsilon subdivisions,2WZN9@28221|Deltaproteobacteria,2Z2EU@29|Myxococcales	28221|Deltaproteobacteria	O	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_54643_1	1524880.A0A076G6J2_9VIRU	3.14e-60	201.0	4QD9Y@10239|Viruses	10239|Viruses	S	Pfam:Terminase_6C	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70037_1	1282876.BAOK01000001_gene3452	9.97e-76	245.0	COG0028@1|root,COG2146@1|root,COG0028@2|Bacteria,COG2146@2|Bacteria,1MWKP@1224|Proteobacteria,2TQK6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	poxB	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_124125_1	1408224.SAMCCGM7_c2350	1.38e-38	147.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,2VF65@28211|Alphaproteobacteria,4BBA2@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase for insertion sequence element	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_31541_1	1249627.D779_1971	1.46e-100	303.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_31542_1	1165841.SULAR_03582	3.65e-15	73.6	COG0589@1|root,COG0589@2|Bacteria,1PDMD@1224|Proteobacteria,43E6X@68525|delta/epsilon subdivisions,2YS51@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_85576_1	1168034.FH5T_12230	9.08e-122	357.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia	976|Bacteroidetes	S	conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_62338_1	745411.B3C1_16636	1.12e-13	72.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1J4U2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_62338_2	1232437.KL662058_gene3950	4.59e-18	86.7	COG0745@1|root,COG1148@1|root,COG0745@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MI9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	CT	NAD(P)-binding Rossmann-like domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
k59_8227_2	1355368.JART01000025_gene126	5.41e-12	67.4	COG2842@1|root,COG2842@2|Bacteria,1PSN7@1224|Proteobacteria,42SI9@68525|delta/epsilon subdivisions,2YRDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
k59_209328_2	944479.JQLX01000010_gene487	1.46e-09	60.8	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2M6RB@213113|Desulfurellales	28221|Deltaproteobacteria	O	Trypsin	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_224811_1	335284.Pcryo_0702	7.31e-07	50.4	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,3NKFP@468|Moraxellaceae	1236|Gammaproteobacteria	KT	Transcriptional regulatory protein, C terminal	copR	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_193809_1	4432.XP_010248289.1	1.2e-48	156.0	2CY54@1|root,2S23H@2759|Eukaryota,3896T@33090|Viridiplantae,3GY43@35493|Streptophyta	35493|Streptophyta	S	Ribosomal protein S10	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_131989_2	395493.BegalDRAFT_1290	1.13e-90	269.0	COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1SZTK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Conserved hypothetical ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_1
k59_62340_1	1125863.JAFN01000001_gene1350	1.23e-82	258.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42N7V@68525|delta/epsilon subdivisions,2WJWF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_15899_1	1265505.ATUG01000001_gene4233	8.32e-89	268.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,42MIJ@68525|delta/epsilon subdivisions,2WJKS@28221|Deltaproteobacteria,2MKBN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k59_15899_2	177437.HRM2_34960	7.57e-20	86.3	COG1176@1|root,COG1176@2|Bacteria,1MVFG@1224|Proteobacteria,43AFR@68525|delta/epsilon subdivisions,2WKHP@28221|Deltaproteobacteria,2MPGD@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k59_46870_1	575540.Isop_2113	7.74e-31	120.0	COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_124141_1	648757.Rvan_1203	9.71e-18	86.3	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,3N6U8@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_93387_1	396588.Tgr7_1169	8.56e-15	78.2	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1WWER@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_193819_1	1168034.FH5T_09195	1.38e-55	192.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_39146_1	522306.CAP2UW1_3159	5.03e-96	288.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_46875_1	243233.MCA1687	7.33e-64	212.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria,1XE3M@135618|Methylococcales	135618|Methylococcales	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
k59_217156_1	1165841.SULAR_03862	3.84e-126	374.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42YPF@68525|delta/epsilon subdivisions,2YRMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_193826_1	1165841.SULAR_09454	2.56e-51	167.0	COG0115@1|root,COG0115@2|Bacteria,1N3ZD@1224|Proteobacteria,42TNN@68525|delta/epsilon subdivisions,2YPU5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Branched-chain amino acid aminotransferase	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k59_193826_2	1165841.SULAR_09459	6.35e-42	140.0	2AMMX@1|root,31CI0@2|Bacteria,1Q8WA@1224|Proteobacteria,42UGB@68525|delta/epsilon subdivisions,2YPW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31557_1	886377.Murru_1017	6.93e-85	264.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia	976|Bacteroidetes	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_240288_1	1046714.AMRX01000008_gene1061	3.9e-92	286.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,4655T@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_62365_1	1122619.KB892341_gene785	1.84e-85	275.0	COG3012@1|root,COG3012@2|Bacteria,1R5E5@1224|Proteobacteria,2VZMD@28216|Betaproteobacteria,3T744@506|Alcaligenaceae	28216|Betaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,SEC-C
k59_108790_1	1201288.M900_1549	9.03e-54	177.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,42QQ1@68525|delta/epsilon subdivisions,2MSYG@213481|Bdellovibrionales,2WMNS@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
k59_85612_1	493475.GARC_4063	4.18e-31	114.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,1SE7M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85613_1	1168034.FH5T_06410	4.68e-69	216.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,2FMKB@200643|Bacteroidia	976|Bacteroidetes	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_85613_2	1168034.FH5T_06400	2.32e-17	76.6	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
k59_116549_1	398578.Daci_3709	6.91e-13	70.1	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,4AB1R@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_232612_1	754477.Q7C_1847	4.58e-35	134.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,45ZQ5@72273|Thiotrichales	72273|Thiotrichales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_39190_1	313628.LNTAR_17733	2.08e-161	461.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_8246_1	1168034.FH5T_15220	2.07e-108	327.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,2FP2A@200643|Bacteroidia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
k59_147423_1	251221.35211219	2.11e-28	116.0	COG0515@1|root,COG0515@2|Bacteria,1G0FM@1117|Cyanobacteria	1117|Cyanobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_201631_1	444157.Tneu_1204	5.49e-40	152.0	COG0574@1|root,arCOG01111@2157|Archaea,2XPWQ@28889|Crenarchaeota	28889|Crenarchaeota	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_201631_2	1265505.ATUG01000001_gene4061	2.57e-18	83.2	COG0589@1|root,COG0745@1|root,COG0589@2|Bacteria,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MQ25@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_77812_1	1089550.ATTH01000001_gene1429	5.05e-39	143.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1FISV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_77812_2	1049564.TevJSym_bb00350	6.24e-15	70.1	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1JBM2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
k59_23626_1	1165841.SULAR_02688	1.46e-64	198.0	COG2105@1|root,COG2105@2|Bacteria,1N814@1224|Proteobacteria,430QM@68525|delta/epsilon subdivisions,2YS0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
k59_23626_2	387093.SUN_1006	5.95e-24	97.4	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,42QE2@68525|delta/epsilon subdivisions,2YNKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_217178_1	1165841.SULAR_04387	6.25e-53	178.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_8252_1	387093.SUN_0169	3.77e-22	95.1	COG2956@1|root,COG2956@2|Bacteria,1PDTB@1224|Proteobacteria,42PNY@68525|delta/epsilon subdivisions,2YN3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ciaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_490_1	4098.XP_009595053.1	2.73e-150	427.0	COG1622@1|root,KOG4767@2759|Eukaryota,37T4F@33090|Viridiplantae,3GGAX@35493|Streptophyta,44JPQ@71274|asterids	35493|Streptophyta	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1	cox2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0042773,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564	-	ko:K02261	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX2,COX2_TM
k59_209359_2	1197477.IA57_06445	7.18e-05	48.9	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
k59_170734_1	264201.pc0398	3.34e-14	77.8	COG1181@1|root,COG1181@2|Bacteria,2JGPF@204428|Chlamydiae	204428|Chlamydiae	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_162917_1	1492737.FEM08_22380	7.92e-52	171.0	COG3952@1|root,COG3952@2|Bacteria,4NH8Q@976|Bacteroidetes,1HYST@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM lipid A biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
k59_139846_1	478741.JAFS01000001_gene1151	1.01e-66	218.0	COG2865@1|root,COG2865@2|Bacteria	2|Bacteria	-	-	mloB	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
k59_147436_1	76869.PputGB1_1746	5.12e-88	275.0	COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,1RS66@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46918_1	82654.Pse7367_1664	1.06e-26	113.0	COG1269@1|root,COG1269@2|Bacteria,1G4AZ@1117|Cyanobacteria,1H77W@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
k59_193863_1	1267535.KB906767_gene5244	9.74e-37	139.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
k59_39198_1	1168034.FH5T_05725	1.9e-141	413.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,2FM9G@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_46920_1	999141.GME_12519	8.29e-54	179.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1XHU9@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_186165_1	1379698.RBG1_1C00001G1704	9.21e-13	68.9	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_139855_1	997352.HMPREF9419_0884	8.17e-14	70.5	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,2FMHP@200643|Bacteroidia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
k59_104255_2	395493.BegalDRAFT_3417	1.21e-41	145.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,460AH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_143236_1	307480.IW16_11370	3.39e-51	174.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia,3ZPYM@59732|Chryseobacterium	976|Bacteroidetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
k59_204939_1	926559.JoomaDRAFT_2625	5.84e-38	143.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,4NFAQ@976|Bacteroidetes,1I0VT@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_2,TPR_6,TPR_8,VWA_2
k59_204939_2	927658.AJUM01000011_gene1317	0.000763	44.7	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,3XJ05@558415|Marinilabiliaceae	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
k59_166435_1	519989.ECTPHS_05200	3.07e-82	255.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RRGA@1236|Gammaproteobacteria,1WX0C@135613|Chromatiales	135613|Chromatiales	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_243597_2	1008459.TASI_0543	1.71e-27	114.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,3T327@506|Alcaligenaceae	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_173942_1	1232437.KL661965_gene3271	4.72e-87	259.0	COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,42TQV@68525|delta/epsilon subdivisions,2WQAE@28221|Deltaproteobacteria,2MKXW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_26979_1	1168034.FH5T_12275	3.19e-124	366.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,2FPXY@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 9.26	tldD3	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_119986_1	1492737.FEM08_15000	1.61e-05	52.4	COG4886@1|root,COG4886@2|Bacteria,4NI2K@976|Bacteroidetes,1I0CI@117743|Flavobacteriia,2NTVA@237|Flavobacterium	976|Bacteroidetes	S	Pfam Leucine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_6,LRR_8
k59_50128_1	491916.RHECIAT_CH0001859	7.9e-33	119.0	29PQU@1|root,31QPX@2|Bacteria,1RKRW@1224|Proteobacteria,2UB5U@28211|Alphaproteobacteria,4BAER@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
k59_50128_2	1387312.BAUS01000002_gene377	3.69e-37	137.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2VIAK@28216|Betaproteobacteria,2KKDV@206350|Nitrosomonadales	206350|Nitrosomonadales	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
k59_81306_1	292459.STH1073	5.53e-39	149.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia	186801|Clostridia	J	Translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_150655_2	1168034.FH5T_10255	1.21e-34	132.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,2FMGF@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_173949_1	1165841.SULAR_00495	1.05e-146	424.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_19020_1	1165841.SULAR_03642	1.15e-119	365.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_243604_1	1206545.S6CLR1_9CAUD	3.01e-27	120.0	4QEE7@10239|Viruses,4QV59@35237|dsDNA viruses  no RNA stage,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42522_1	1121396.KB893024_gene3918	8.41e-35	135.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2WKBP@28221|Deltaproteobacteria,2MI3W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,Sulfatase
k59_81314_1	2340.JV46_24180	5.28e-53	171.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1J50E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_65657_2	580331.Thit_2250	1.36e-26	103.0	COG5573@1|root,COG5573@2|Bacteria,1V7GS@1239|Firmicutes,24JFR@186801|Clostridia,42GMN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_135306_1	582345.D6RRL6_BPKPP	2.8e-62	206.0	4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses  no RNA stage,4QQ2S@28883|Caudovirales	28883|Caudovirales	S	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166443_2	1384054.N790_05295	1.02e-50	181.0	COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,1RXI3@1236|Gammaproteobacteria,1X70I@135614|Xanthomonadales	135614|Xanthomonadales	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_143249_1	1042375.AFPL01000046_gene1820	1.15e-31	120.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,1RYY7@1236|Gammaproteobacteria,467AJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_181893_1	1165841.SULAR_07435	8.39e-09	60.8	COG4773@1|root,COG4773@2|Bacteria,1PP2I@1224|Proteobacteria,42WFP@68525|delta/epsilon subdivisions,2YQM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_65660_1	1123261.AXDW01000004_gene2883	6.87e-98	311.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1X91U@135614|Xanthomonadales	135614|Xanthomonadales	G	Carbohydrate phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3417,Phosphorylase
k59_236011_1	1149133.ppKF707_3900	2.83e-110	344.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1YDGZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_4079_1	543913.D521_1714	3.21e-44	156.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1KPWM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Coenzyme metabolism Energy production and conversion	ascD	-	1.17.1.1	ko:K00523,ko:K18248	ko00520,ko00627,ko01120,map00520,map00627,map01120	M00637	R00823,R00825,R03391,R03392	RC00192,RC00230	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_50156_2	1123234.AUKI01000002_gene1750	1.95e-94	290.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_127796_1	396588.Tgr7_1949	1.34e-47	157.0	COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,1S8F6@1236|Gammaproteobacteria,1X1E9@135613|Chromatiales	135613|Chromatiales	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
k59_127796_2	1230343.CANP01000052_gene3843	4.83e-44	155.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1JCZT@118969|Legionellales	118969|Legionellales	H	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_27002_1	926550.CLDAP_31800	4.64e-51	192.0	COG1672@1|root,COG3292@1|root,COG1672@2|Bacteria,COG3292@2|Bacteria,2G9I0@200795|Chloroflexi	200795|Chloroflexi	K	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_81326_1	765420.OSCT_2727	3.95e-10	63.9	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
k59_181897_1	292564.Cyagr_2365	9.73e-28	107.0	COG1846@1|root,COG1846@2|Bacteria,1G5RS@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_189517_2	1165841.SULAR_00560	1.72e-81	252.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMVY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_120016_1	857087.Metme_4110	5.33e-32	125.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1XEC9@135618|Methylococcales	135618|Methylococcales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k59_19054_1	1242864.D187_003201	9.03e-77	249.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,1QX5Y@1224|Proteobacteria,42PKC@68525|delta/epsilon subdivisions,2WISI@28221|Deltaproteobacteria,2YYJ2@29|Myxococcales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
k59_150698_1	1279019.ARQK01000036_gene1636	2.93e-106	317.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_57923_1	387093.SUN_1857	1.5e-58	204.0	COG0784@1|root,COG2202@1|root,COG3287@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3287@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2YTEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two-component sensor histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,Response_reg
k59_143279_1	269796.Rru_A0223	2.01e-66	220.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,2JPV0@204441|Rhodospirillales	204441|Rhodospirillales	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_158557_1	235909.GKP02	2.15e-24	105.0	COG5527@1|root,COG5527@2|Bacteria,1V1XJ@1239|Firmicutes,4HGH6@91061|Bacilli	91061|Bacilli	L	Protein involved in initiation of plasmid replication	-	-	-	-	-	-	-	-	-	-	-	-	L_lactis_RepB_C,Rep_3
k59_81340_1	1121875.KB907547_gene3013	3.87e-59	189.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_81340_2	313596.RB2501_08890	8.17e-19	79.3	2E33D@1|root,32Y3H@2|Bacteria,4NVRK@976|Bacteroidetes,1I502@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_19066_1	1216967.L100_16215	7.63e-21	98.6	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia,34PUP@308865|Elizabethkingia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_204997_1	1168034.FH5T_03520	4.69e-86	263.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42559_1	2340.JV46_16820	2.4e-111	325.0	COG0730@1|root,COG0730@2|Bacteria,1QJ79@1224|Proteobacteria,1TH4W@1236|Gammaproteobacteria,1J7SI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_81344_1	555779.Dthio_PD3191	4.53e-23	94.7	COG3012@1|root,COG3012@2|Bacteria,1QU5B@1224|Proteobacteria,43D30@68525|delta/epsilon subdivisions,2X8A5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
k59_104309_1	28532.XP_010532348.1	1.15e-40	153.0	COG2801@1|root,COG4284@1|root,KOG0017@2759|Eukaryota,KOG2388@2759|Eukaryota,37MVU@33090|Viridiplantae,3GGIU@35493|Streptophyta,3HSQP@3699|Brassicales	35493|Streptophyta	M	udp-sugar	USP	GO:0003674,GO:0003824,GO:0003983,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006011,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009555,GO:0009987,GO:0010035,GO:0010038,GO:0010491,GO:0016740,GO:0016772,GO:0016779,GO:0017103,GO:0018130,GO:0019438,GO:0019752,GO:0032501,GO:0032502,GO:0033356,GO:0034641,GO:0034654,GO:0042221,GO:0042995,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046398,GO:0046483,GO:0046686,GO:0047338,GO:0047350,GO:0048229,GO:0048856,GO:0050896,GO:0051748,GO:0052573,GO:0055086,GO:0070569,GO:0071704,GO:0090406,GO:0120025,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	2.7.7.64	ko:K12447	ko00040,ko00052,ko00053,ko00520,ko01100,ko01130,map00040,map00052,map00053,map00520,map01100,map01130	M00014	R00289,R00502,R01381,R03077,R08845	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
k59_81347_1	335543.Sfum_3056	4.91e-92	280.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2MQ7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_181916_1	1117318.PRUB_03471	3.22e-93	286.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,2Q15S@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
k59_220601_1	694569.D7S_01787	4.82e-68	227.0	COG0144@1|root,COG0223@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0223@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1Y781@135625|Pasteurellales	135625|Pasteurellales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
k59_220601_2	981327.F925_00514	3e-11	61.2	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,3NKDT@468|Moraxellaceae	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_50184_2	98439.AJLL01000075_gene887	2.67e-13	65.9	2AGP1@1|root,316WK@2|Bacteria,1GKU8@1117|Cyanobacteria,1JMR8@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120033_1	748247.AZKH_4345	1.15e-85	282.0	COG0247@1|root,COG0277@1|root,COG1145@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG1145@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KUWB@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_112299_1	317025.Tcr_1997	1.51e-53	182.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,461K7@72273|Thiotrichales	72273|Thiotrichales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_112572_1	1410619.SRDD_02430	2.07e-22	92.4	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RRT6@1236|Gammaproteobacteria,402MZ@613|Serratia	1236|Gammaproteobacteria	T	Transcriptional regulatory protein, C terminal	phoP_1	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_112572_2	2340.JV46_11760	2.34e-56	184.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1J4K1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_197826_1	1165841.SULAR_08567	4.6e-44	152.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2YMPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0324 family	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_197826_2	1165841.SULAR_08572	1.34e-100	298.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_89210_1	1444712.BN1013_02408	2.31e-89	275.0	COG4834@1|root,COG4834@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2184)	Z012_11565	-	-	-	-	-	-	-	-	-	-	-	DUF2184
k59_135687_1	635013.TherJR_2850	5.25e-30	124.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_120335_1	1499967.BAYZ01000105_gene3533	2.22e-17	86.3	COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria	2|Bacteria	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_151058_1	2340.JV46_15340	1.74e-64	205.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,1J5H6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta-lactamase superfamily I	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_19435_1	1254432.SCE1572_12305	7.01e-12	69.7	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1QA6R@1224|Proteobacteria,438FC@68525|delta/epsilon subdivisions,2X3QC@28221|Deltaproteobacteria,2YWU9@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
k59_143630_1	1123514.KB905899_gene1933	5.33e-87	266.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_58249_1	1049564.TevJSym_ac00140	6.34e-37	136.0	COG1999@1|root,COG4531@1|root,COG1999@2|Bacteria,COG4531@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,1J6I1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC,ZnuA
k59_228467_2	1089551.KE386572_gene1163	0.000407	46.2	COG0500@1|root,COG2226@2|Bacteria,1N6XZ@1224|Proteobacteria	1224|Proteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
k59_197830_1	83406.HDN1F_16340	3.38e-103	314.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1J4HM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125	GATase_6,Pribosyltran
k59_13971_1	41875.XP_007512769.1	1.47e-15	74.3	2C9B9@1|root,2S8T7@2759|Eukaryota	2759|Eukaryota	S	HopJ type III effector protein	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
k59_13971_2	2340.JV46_05350	5.61e-69	214.0	COG3439@1|root,COG3439@2|Bacteria,1NDCV@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_215238_1	313612.L8106_02532	1.83e-19	84.3	COG3335@1|root,COG3335@2|Bacteria,1G6HS@1117|Cyanobacteria,1HH5N@1150|Oscillatoriales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_215238_2	1399147.P618_200004	3.79e-05	44.3	COG3293@1|root,COG3293@2|Bacteria,1MZS4@1224|Proteobacteria,2TXCF@28211|Alphaproteobacteria,47EZ1@766|Rickettsiales	766|Rickettsiales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_52698_1	1174528.JH992890_gene608	3.64e-37	143.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_68396_1	411684.HPDFL43_08674	1.07e-47	155.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,43JP2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	gloA	GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_238558_1	983548.Krodi_0263	1.36e-79	248.0	COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1HZYM@117743|Flavobacteriia,37FKT@326319|Dokdonia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	LeuA_dimer,PALP
k59_13981_1	1168034.FH5T_04745	3.21e-43	151.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,2FN63@200643|Bacteroidia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_13981_2	1168034.FH5T_04750	1.24e-67	212.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,2FN64@200643|Bacteroidia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_130312_2	1444711.CCJF01000003_gene35	2.06e-55	200.0	2DBB8@1|root,2Z867@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3383)	Z012_10460	-	-	-	-	-	-	-	-	-	-	-	DUF3383
k59_122661_1	395493.BegalDRAFT_0032	7.72e-67	212.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_76222_1	983917.RGE_03970	5.17e-113	335.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,1KJEX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_146204_1	1123405.AUMM01000075_gene130	4.63e-36	128.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,26NH7@186821|Sporolactobacillaceae	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_146204_2	1250006.JHZZ01000001_gene2268	6.03e-07	51.6	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia,3VW00@52959|Polaribacter	976|Bacteroidetes	L	EXOIII	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_60539_1	1123518.ARWI01000001_gene1637	6.17e-24	101.0	COG2834@1|root,COG2834@2|Bacteria,1R8JU@1224|Proteobacteria,1SKB0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76225_1	323261.Noc_2134	1.18e-50	176.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1X0HC@135613|Chromatiales	135613|Chromatiales	C	PFAM Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_192189_1	367737.Abu_0826	3.33e-76	241.0	COG4277@1|root,COG4277@2|Bacteria,1MVCV@1224|Proteobacteria,42NNA@68525|delta/epsilon subdivisions,2YR3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_200070_1	1168034.FH5T_13710	3.95e-49	163.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,2FP2H@200643|Bacteroidia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_45052_1	1168034.FH5T_04100	2.74e-112	336.0	COG1073@1|root,COG1073@2|Bacteria,4NFCA@976|Bacteroidetes,2FP8B@200643|Bacteroidia	976|Bacteroidetes	S	PS-10 peptidase S37	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S37
k59_169289_1	1165841.SULAR_06233	4.48e-153	439.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2YMR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_68404_1	1165841.SULAR_10444	1.23e-105	315.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2YMQH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_68404_2	1165841.SULAR_10449	6.48e-06	45.8	COG0314@1|root,COG0314@2|Bacteria,1Q97D@1224|Proteobacteria,42REX@68525|delta/epsilon subdivisions,2YP4E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_21784_1	754477.Q7C_2526	1.14e-132	386.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,4601W@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_130344_1	794903.OPIT5_10535	2.73e-49	172.0	COG2072@1|root,COG2072@2|Bacteria,46TFP@74201|Verrucomicrobia,3K9DS@414999|Opitutae	414999|Opitutae	P	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
k59_83661_1	1168034.FH5T_08925	2.82e-50	171.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,2FNAB@200643|Bacteroidia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_146215_1	313603.FB2170_02785	2.3e-115	340.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1HXIP@117743|Flavobacteriia,2PGYT@252356|Maribacter	976|Bacteroidetes	O	ClpX C4-type zinc finger	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_76233_1	7668.SPU_025907-tr	5.76e-61	199.0	2BEH2@1|root,2S14S@2759|Eukaryota,39MAV@33154|Opisthokonta,3CNXX@33208|Metazoa,3E63V@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_153323_1	696747.NIES39_K03130	0.000103	50.8	COG1357@1|root,COG2319@1|root,COG5635@1|root,COG1357@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1FZVW@1117|Cyanobacteria,1H8VD@1150|Oscillatoriales	1117|Cyanobacteria	T	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
k59_192200_1	1166018.FAES_5268	2.51e-23	101.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_215269_1	391165.GbCGDNIH1_1554	2.71e-19	87.8	COG4540@1|root,COG4540@2|Bacteria	2|Bacteria	L	Baseplate assembly protein	Z012_12225	-	-	-	-	-	-	-	-	-	-	-	Phage_base_V
k59_91443_1	102129.Lepto7375DRAFT_2974	1.3e-09	55.5	COG1359@1|root,COG1359@2|Bacteria,1G8H0@1117|Cyanobacteria,1HC7H@1150|Oscillatoriales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_91443_2	1123518.ARWI01000001_gene1856	6.41e-18	80.5	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,46139@72273|Thiotrichales	72273|Thiotrichales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_13993_1	1168289.AJKI01000002_gene2510	1.56e-08	55.1	COG2849@1|root,COG2849@2|Bacteria,4NUDS@976|Bacteroidetes,2FTTJ@200643|Bacteroidia,3XK3X@558415|Marinilabiliaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
k59_114769_1	551275.KB899547_gene419	1.04e-06	52.4	2EH8B@1|root,33B05@2|Bacteria,1NQEC@1224|Proteobacteria,2UVZH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114769_2	83219.PM02_06820	5.37e-30	110.0	COG3795@1|root,COG3795@2|Bacteria,1RJJG@1224|Proteobacteria,2UCR2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_68420_1	378806.STAUR_8307	6.54e-37	143.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,438D9@68525|delta/epsilon subdivisions,2X3NF@28221|Deltaproteobacteria,2YWN6@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_169306_1	395493.BegalDRAFT_2372	2.34e-71	228.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,1QWW7@1224|Proteobacteria,1T4BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_14000_2	631362.Thi970DRAFT_01545	3.69e-25	106.0	COG1807@1|root,COG1807@2|Bacteria,1RHMW@1224|Proteobacteria,1SPI6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_122697_1	1165841.SULAR_04572	1.55e-34	122.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2YQ46@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_122697_2	1165841.SULAR_04577	1.19e-60	192.0	COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,43BAA@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	paraquat-inducible protein A	pqiA2	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_37629_2	1175654.A0A0S0N8I3_9CAUD	2.51e-49	180.0	4QCWX@10239|Viruses,4QYGT@35237|dsDNA viruses  no RNA stage,4QU1G@28883|Caudovirales,4QMA7@10699|Siphoviridae	10699|Siphoviridae	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192208_1	1165841.SULAR_10349	9.95e-119	360.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_114774_1	313596.RB2501_09950	1.34e-62	194.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1I17M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_114774_2	313596.RB2501_09955	4.12e-79	247.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_230576_1	1168034.FH5T_07965	1.69e-20	90.9	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_21809_1	143224.JQMD01000002_gene730	8.61e-38	139.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1HYBN@117743|Flavobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
k59_130356_1	1249480.B649_00860	1.75e-43	142.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2YPS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_130356_2	387093.SUN_2343	2.32e-16	70.5	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2YQQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
k59_223172_1	2340.JV46_27680	1.71e-31	122.0	COG0810@1|root,COG0810@2|Bacteria,1PDUW@1224|Proteobacteria,1TH8Z@1236|Gammaproteobacteria,1JB81@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2
k59_223172_2	2340.JV46_27690	4.13e-22	96.3	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1J4F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_122703_1	697282.Mettu_0065	1.02e-101	310.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	twitching motility protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_68780_2	1165841.SULAR_05573	5.26e-16	76.6	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_61004_2	5145.XP_001910110.1	2.61e-32	128.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3NW85@4751|Fungi,3QMJB@4890|Ascomycota,21190@147550|Sordariomycetes,3UAPA@5139|Sordariales	4751|Fungi	F	Carbamoyl-phosphate synthase small chain, CPSase domain	URA2	GO:0000050,GO:0003674,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009892,GO:0009987,GO:0016020,GO:0016021,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019219,GO:0019222,GO:0019627,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045934,GO:0045984,GO:0046112,GO:0046394,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0055086,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0080090,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.2,6.3.5.5	ko:K01954,ko:K11541	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R01397,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS,OTCace,OTCace_N
k59_246574_1	1165841.SULAR_02898	3.28e-108	320.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2YMQU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_223528_1	2340.JV46_17160	2.05e-109	330.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1J5M7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_107200_1	1165841.SULAR_10539	1.38e-108	333.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_84049_1	1165841.SULAR_07153	3.26e-138	422.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2YSXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
k59_215658_2	1116375.VEJY3_21521	4.92e-21	88.2	COG4583@1|root,COG4583@2|Bacteria,1PNCY@1224|Proteobacteria,1TA91@1236|Gammaproteobacteria,1Y1BQ@135623|Vibrionales	135623|Vibrionales	E	COG4583 Sarcosine oxidase gamma subunit	-	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
k59_45466_1	1168034.FH5T_05030	4.65e-82	253.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,2FNJF@200643|Bacteroidia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k59_45466_2	1168034.FH5T_05035	2.84e-15	71.6	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,2FUC5@200643|Bacteroidia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_239038_1	555778.Hneap_1706	1.3e-37	128.0	COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,1SAV8@1236|Gammaproteobacteria,1WZPV@135613|Chromatiales	135613|Chromatiales	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_239038_2	2340.JV46_20180	7.57e-12	64.3	2C8PG@1|root,32RMK@2|Bacteria,1N0UQ@1224|Proteobacteria,1SBBP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130745_1	1121920.AUAU01000011_gene198	5.87e-21	99.8	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
k59_45467_1	1165841.SULAR_08397	1.84e-104	312.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2YMQ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_61013_1	697282.Mettu_0052	1.25e-35	136.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XE33@135618|Methylococcales	135618|Methylococcales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_184880_1	706587.Desti_1031	3.12e-07	59.7	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	HlyD_D23
k59_123145_1	313612.L8106_20760	1.25e-12	73.2	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H9JN@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_138223_2	1268622.AVS7_01850	3.38e-05	50.1	COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2VK1H@28216|Betaproteobacteria,4AHCT@80864|Comamonadaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_115161_1	472759.Nhal_1189	6.06e-56	198.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_200485_1	1165841.SULAR_05803	8.19e-130	375.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2YN3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_211157_1	449673.BACSTE_03217	8.26e-15	80.9	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMCC@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_95240_1	1056820.KB900638_gene71	2.6e-69	218.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,1RMVC@1236|Gammaproteobacteria,2PQ4P@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N,GST_N_3
k59_79750_1	930171.Asphe3_14360	8.02e-37	142.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,1W7VF@1268|Micrococcaceae	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
k59_87352_1	395493.BegalDRAFT_0892	1.74e-74	243.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,45ZUE@72273|Thiotrichales	72273|Thiotrichales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_41149_2	519989.ECTPHS_03769	1.49e-65	205.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1WVVN@135613|Chromatiales	135613|Chromatiales	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_164878_1	28229.ND2E_3765	7.36e-91	279.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,2Q5U2@267889|Colwelliaceae	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_203493_1	1217718.ALOU01000019_gene2684	5.54e-15	80.1	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1K2VF@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
k59_203493_2	84531.JMTZ01000120_gene4247	3.84e-13	68.6	COG2197@1|root,COG2197@2|Bacteria,1RAQG@1224|Proteobacteria,1S31E@1236|Gammaproteobacteria,1X4HP@135614|Xanthomonadales	135614|Xanthomonadales	K	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_180348_1	946362.XP_004995507.1	4.54e-37	146.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta	33154|Opisthokonta	G	retrotransposable element Tf2 155 kDa protein type 1-like	-	-	-	-	-	-	-	-	-	-	-	-	PNMA,RVT_1,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_141601_1	2340.JV46_29200	4.98e-120	350.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1J4GM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_71829_1	929713.NIASO_18395	1.52e-29	120.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1IQ2K@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_71829_2	1094466.KQS_05465	2.58e-27	112.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,1HWWQ@117743|Flavobacteriia,2NTXP@237|Flavobacterium	976|Bacteroidetes	P	Iron ABC transporter	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
k59_87356_1	1165841.SULAR_00125	1.22e-85	255.0	COG3439@1|root,COG3439@2|Bacteria,1REDZ@1224|Proteobacteria,42T1V@68525|delta/epsilon subdivisions,2YPRR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_17633_1	387093.SUN_0010	2.19e-26	105.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2YN5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_17633_2	1165841.SULAR_08512	5.86e-81	243.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928	GTP_cyclohydroI
k59_102852_1	387093.SUN_0559	7.68e-86	281.0	COG3439@1|root,COG3439@2|Bacteria,1PWY7@1224|Proteobacteria,42Y9J@68525|delta/epsilon subdivisions,2YRF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188071_1	272134.KB731324_gene1426	6.71e-32	129.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD
k59_203497_1	28229.ND2E_2839	1.93e-91	290.0	COG0265@1|root,COG0265@2|Bacteria,1MWCG@1224|Proteobacteria	1224|Proteobacteria	O	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
k59_141603_1	933262.AXAM01000004_gene2414	1.94e-59	206.0	COG1196@1|root,COG4717@1|root,COG1196@2|Bacteria,COG4717@2|Bacteria,1MVAW@1224|Proteobacteria,42MYC@68525|delta/epsilon subdivisions,2WJXA@28221|Deltaproteobacteria,2MJBC@213118|Desulfobacterales	28221|Deltaproteobacteria	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
k59_180358_2	388413.ALPR1_10675	2.1e-34	122.0	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,47Q8Q@768503|Cytophagia	976|Bacteroidetes	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k59_64225_1	1123037.AUDE01000005_gene3088	4.38e-30	118.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
k59_95274_1	2340.JV46_13540	1.12e-98	303.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1J589@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_33567_1	883078.HMPREF9695_00465	8.36e-84	257.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,3JS1E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve
k59_141615_1	857087.Metme_1583	2.65e-48	169.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,1RPB3@1236|Gammaproteobacteria,1XDNQ@135618|Methylococcales	135618|Methylococcales	C	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
k59_141615_2	395493.BegalDRAFT_0210	4.9e-11	63.5	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJPC@1224|Proteobacteria,1SZ4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_Tnp_IS630
k59_25565_1	1286106.MPL1_03835	5.95e-158	459.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_118529_1	395493.BegalDRAFT_1056	8.2e-34	123.0	COG1432@1|root,COG1432@2|Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD,NYN
k59_118529_2	306281.AJLK01000010_gene5807	9.48e-64	202.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1JHDR@1189|Stigonemataceae	1117|Cyanobacteria	H	Pfam:PNPOx_C	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
k59_25568_1	748658.KB907313_gene2213	6.81e-80	263.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales	135613|Chromatiales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_110663_1	572480.Arnit_1228	1.82e-89	280.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2YTEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_157027_1	472759.Nhal_0485	5.83e-87	275.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1WX75@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_79763_1	1202532.FF52_14619	4.61e-45	154.0	28MUU@1|root,2ZB2K@2|Bacteria,4NK92@976|Bacteroidetes,1HZPD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_172591_1	637905.SVI_1657	1.18e-24	107.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,2QAPJ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_118535_1	1049564.TevJSym_ai00930	2.93e-53	182.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1J5X5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_118535_2	870187.Thini_2454	5.49e-45	152.0	COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,1S5P4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_118535_3	870187.Thini_0307	5.95e-42	144.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_180371_1	616991.JPOO01000003_gene646	3.56e-08	62.4	COG2207@1|root,COG5616@1|root,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia,23HS2@178469|Arenibacter	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
k59_149256_1	388413.ALPR1_11965	2.8e-212	607.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47TP1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_226612_1	1165841.SULAR_09394	1.85e-115	340.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_211187_1	1408473.JHXO01000001_gene2411	2.89e-05	45.1	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel family protein	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_17920_1	1437882.AZRU01000026_gene5980	5.14e-35	140.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1YDKA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_103124_1	207954.MED92_12786	3.52e-96	298.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1XH2R@135619|Oceanospirillales	135619|Oceanospirillales	P	COG1283 Na phosphate symporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_64529_1	489825.LYNGBM3L_71300	7.84e-63	211.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	AAA_16,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_141901_1	1278309.KB907099_gene2875	4.99e-96	286.0	COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,1RRSG@1236|Gammaproteobacteria,1XJ27@135619|Oceanospirillales	135619|Oceanospirillales	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_141901_2	1122599.AUGR01000018_gene3987	3.72e-09	53.5	COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,1S7F4@1236|Gammaproteobacteria,1XK2N@135619|Oceanospirillales	135619|Oceanospirillales	Q	Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
k59_226922_1	556269.ACDQ01000011_gene401	1.22e-47	161.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,4731T@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_48980_1	1165841.SULAR_08874	5.87e-108	325.0	COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,43DZE@68525|delta/epsilon subdivisions,2YRGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
k59_10579_1	1355368.JART01000010_gene1984	2.17e-23	103.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,SBP_bac_3
k59_172834_2	32024.JMTI01000004_gene1910	5.21e-15	74.3	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42RJM@68525|delta/epsilon subdivisions,2YP5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_203774_1	2340.JV46_11330	4.98e-55	177.0	COG3090@1|root,COG3090@2|Bacteria,1NK6X@1224|Proteobacteria	1224|Proteobacteria	G	TRAP dicarboxylate transporter, DctQ subunit	dctQ2	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_72212_2	2340.JV46_23650	2.54e-103	312.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1J4PB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_41459_1	1165841.SULAR_07470	1.87e-140	405.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_157368_1	246197.MXAN_1653	1.34e-86	265.0	COG1398@1|root,COG1398@2|Bacteria	2|Bacteria	I	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_157375_1	373994.Riv7116_5511	1.89e-41	144.0	COG2230@1|root,COG2230@2|Bacteria,1GEES@1117|Cyanobacteria	1117|Cyanobacteria	M	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	CMAS
k59_157375_2	1173028.ANKO01000112_gene4853	5.85e-22	94.7	COG2124@1|root,COG2124@2|Bacteria,1G57F@1117|Cyanobacteria,1HBQ7@1150|Oscillatoriales	1117|Cyanobacteria	C	Cytochrome P450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
k59_25874_1	1049564.TevJSym_bb00230	2.12e-114	365.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_203787_1	3983.cassava4.1_010787m	1.25e-18	87.8	COG1515@1|root,KOG4417@2759|Eukaryota,37NHV@33090|Viridiplantae,3GG9X@35493|Streptophyta,4JD5S@91835|fabids	35493|Streptophyta	L	endonuclease	-	GO:0000287,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004536,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016888,GO:0016891,GO:0016893,GO:0031974,GO:0031981,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901363	-	ko:K21813	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
k59_180729_2	768671.ThimaDRAFT_2585	1.98e-55	193.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1WWQF@135613|Chromatiales	135613|Chromatiales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_180729_3	391735.Veis_0001	3.33e-17	83.2	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,4AAHN@80864|Comamonadaceae	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_49001_1	765913.ThidrDRAFT_2347	1.02e-59	190.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1WX3P@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
k59_49001_2	1232683.ADIMK_2773	1.73e-24	103.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,463YJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_95561_1	383407.XOC_4156	4.25e-21	91.7	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1X6EW@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_49003_1	1165841.SULAR_00690	8.44e-89	287.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_141922_1	1165841.SULAR_09374	1.53e-67	216.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_141922_2	1165841.SULAR_09369	8.1e-18	81.3	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	ydiY	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF3078,DUF481
k59_80098_1	1177181.T9A_01715	2.21e-30	127.0	COG1073@1|root,COG1073@2|Bacteria,1NVTC@1224|Proteobacteria,1RNXQ@1236|Gammaproteobacteria,1XJQ7@135619|Oceanospirillales	135619|Oceanospirillales	I	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N
k59_183145_1	313596.RB2501_03685	3.87e-167	480.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_5265_1	756272.Plabr_3518	7.11e-79	263.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
k59_214015_1	933262.AXAM01000016_gene149	2.47e-66	224.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_167848_1	1121405.dsmv_0891	5.13e-26	99.4	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria,2MMAB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214019_1	98439.AJLL01000047_gene2888	2.23e-95	291.0	2DB98@1|root,2Z7VA@2|Bacteria,1G05J@1117|Cyanobacteria,1JHH9@1189|Stigonemataceae	1117|Cyanobacteria	P	Photosystem II protein	psbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_206175_1	1165841.SULAR_02953	3.63e-80	255.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_244933_2	1165841.SULAR_05543	5.22e-75	240.0	COG0642@1|root,COG4564@1|root,COG0642@2|Bacteria,COG4564@2|Bacteria,1QZ2C@1224|Proteobacteria,42QBR@68525|delta/epsilon subdivisions,2YNQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_2,sCache_2
k59_98034_1	1336235.JAEG01000018_gene3348	5.44e-05	45.8	COG3668@1|root,COG3668@2|Bacteria,1N9GA@1224|Proteobacteria,2UFUV@28211|Alphaproteobacteria,4BGAA@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_98034_2	29581.BW37_05122	2.09e-24	93.6	COG3609@1|root,COG3609@2|Bacteria,1N1K5@1224|Proteobacteria,2VVEQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
k59_244935_1	1437882.AZRU01000068_gene5025	9.75e-73	233.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1YCR1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	JKL	Belongs to the DEAD box helicase family	dbpA	GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_74783_2	1165841.SULAR_03622	8.19e-102	299.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2YRUU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_113451_1	373994.Riv7116_3152	2.3e-23	99.4	COG0591@1|root,COG0591@2|Bacteria,1G2XQ@1117|Cyanobacteria,1HM4M@1161|Nostocales	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_43850_2	388401.RB2150_07718	1.45e-05	47.8	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,2UBXI@28211|Alphaproteobacteria,3ZHSJ@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
k59_12737_1	232346.JHQL01000007_gene2029	2.7e-71	229.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,1RPND@1236|Gammaproteobacteria,1XNVX@135619|Oceanospirillales	135619|Oceanospirillales	S	TraB family	-	-	-	-	-	-	-	-	-	-	-	-	TraB
k59_190889_1	1250232.JQNJ01000001_gene649	2.27e-118	342.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1HXNN@117743|Flavobacteriia	976|Bacteroidetes	Q	abc transporter (atp-binding protein)	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_190889_2	313596.RB2501_09675	1.78e-15	75.9	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1HXBV@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_214032_1	1165841.SULAR_00230	5.45e-78	249.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_206185_1	1280952.HJA_06612	0.000172	43.9	COG0762@1|root,COG0762@2|Bacteria,1PSC3@1224|Proteobacteria,2V4J4@28211|Alphaproteobacteria,43YXY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
k59_206185_2	1485544.JQKP01000002_gene1636	1.12e-16	75.9	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,44VYI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
k59_105516_1	1165841.SULAR_02943	6.11e-11	62.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_105516_2	1165841.SULAR_02938	1.33e-116	348.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hydB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_20301_1	932213.SPM24T3_05436	3.79e-30	113.0	COG0454@1|root,COG0456@2|Bacteria,1QTY5@1224|Proteobacteria,1S6M9@1236|Gammaproteobacteria,402C6@613|Serratia	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	speG_2	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_167875_1	1168034.FH5T_00285	2.7e-51	163.0	COG3288@1|root,COG3288@2|Bacteria,4NT78@976|Bacteroidetes,2FU0R@200643|Bacteroidia	976|Bacteroidetes	C	Pyridine nucleotide transhydrogenase	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
k59_167875_2	1168034.FH5T_00280	1.5e-56	186.0	COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,2G2N7@200643|Bacteroidia	976|Bacteroidetes	C	NAD(P)( ) transhydrogenase (AB-specific), alpha subunit	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_159827_1	1137799.GZ78_12405	4.09e-21	96.3	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XIR3@135619|Oceanospirillales	135619|Oceanospirillales	H	biosynthesis protein HemY	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_7
k59_51480_1	1168034.FH5T_04995	4.84e-42	139.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 9.82	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
k59_51480_2	391587.KAOT1_14567	1.51e-08	55.1	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1HWSY@117743|Flavobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_67190_1	765910.MARPU_15380	5.87e-45	167.0	COG0651@1|root,COG0651@2|Bacteria,1N6BY@1224|Proteobacteria,1RR4C@1236|Gammaproteobacteria,1WWFY@135613|Chromatiales	135613|Chromatiales	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Proton_antipo_M
k59_105518_1	1300345.LF41_2902	2.04e-43	155.0	arCOG10603@1|root,32SV6@2|Bacteria,1MYDK@1224|Proteobacteria,1SG7U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43856_1	317619.ANKN01000179_gene1568	3.64e-13	76.3	COG0768@1|root,COG0768@2|Bacteria,1G0ZK@1117|Cyanobacteria,1MKBX@1212|Prochloraceae	1117|Cyanobacteria	M	Cell division protein FtsI	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_214042_1	387093.SUN_1640	6.92e-26	104.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2YNUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_214042_2	1165841.SULAR_05258	7.29e-36	124.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2YPEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_221746_1	566466.NOR53_3441	5.3e-118	353.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1J7W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_167880_1	1121875.KB907547_gene3261	8.79e-99	315.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1HXWA@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_75130_1	1458462.JNLK01000001_gene527	1.27e-13	77.4	COG0553@1|root,COG4646@1|root,COG0553@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,27IX0@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,MutS_I,ResIII,SNF2_N
k59_59537_2	90813.JQMT01000001_gene1998	6.78e-14	70.5	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,461UQ@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_20683_1	754476.Q7A_24	4.93e-22	97.1	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,463VV@72273|Thiotrichales	72273|Thiotrichales	T	SH3 domain	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k59_20683_2	339670.Bamb_2601	2.26e-25	104.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,1K2FN@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_245189_1	715451.ambt_18185	9.27e-61	209.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,46425@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Efflux pump	ttgB	-	-	ko:K18138,ko:K18299	ko01501,ko01503,map01501,map01503	M00641,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.16	-	-	ACR_tran
k59_245189_2	358220.C380_02075	9.12e-12	66.6	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,4AAYK@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_67476_1	1168034.FH5T_00795	8.14e-96	306.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_229560_1	224324.aq_1166	4.84e-47	157.0	COG0226@1|root,COG0226@2|Bacteria,2G4ST@200783|Aquificae	200783|Aquificae	P	PFAM CO dehydrogenase beta subunit acetyl-CoA synthase epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	CO_dh
k59_229560_2	1165841.SULAR_00985	2.11e-29	114.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_222107_1	1165841.SULAR_00015	4.3e-122	360.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2YNFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_168171_1	1165841.SULAR_00505	2.76e-105	318.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,42XAR@68525|delta/epsilon subdivisions,2YR2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_51793_1	318161.Sden_3360	8.57e-93	281.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,2Q9Q5@267890|Shewanellaceae	1236|Gammaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_20697_1	216596.RL3058	3.36e-66	216.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2TUR1@28211|Alphaproteobacteria,4B93D@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_191187_1	667632.KB890165_gene2619	5.55e-82	256.0	COG1879@1|root,COG1879@2|Bacteria,1MUJU@1224|Proteobacteria,2VJED@28216|Betaproteobacteria,1K4RC@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_191188_1	29730.Gorai.001G162000.1	6.97e-157	446.0	COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,3GF4E@35493|Streptophyta	35493|Streptophyta	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis	cob	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_168173_1	358220.C380_15560	1.5e-19	87.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4A9QA@80864|Comamonadaceae	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_168173_2	870187.Thini_4124	9.06e-06	45.4	COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Cbb3-type cytochrome oxidase, subunit 3	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_168173_3	870187.Thini_4123	4.8e-73	224.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_183495_2	187272.Mlg_2678	6.88e-29	114.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1WWHP@135613|Chromatiales	135613|Chromatiales	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_51803_1	1168034.FH5T_12885	2.23e-30	110.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,2FRZ6@200643|Bacteroidia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_51803_2	1121097.JCM15093_3350	9.05e-49	156.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,2FTD0@200643|Bacteroidia,4AQZ4@815|Bacteroidaceae	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_229571_1	1125863.JAFN01000001_gene1312	4.05e-46	164.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,42MYY@68525|delta/epsilon subdivisions,2WJ6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SpoVR family protein	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_160120_1	546268.NEISUBOT_03712	1.38e-116	340.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,2KPIK@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_44137_1	56110.Oscil6304_5722	2.12e-26	100.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_44137_2	491205.JARQ01000003_gene2110	5.36e-06	48.5	COG1331@1|root,COG1331@2|Bacteria,4NJ7T@976|Bacteroidetes,1I0YH@117743|Flavobacteriia,3ZPZA@59732|Chryseobacterium	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
k59_160122_1	2340.JV46_27090	6.54e-75	234.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1J95I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_214314_1	1196835.A458_16745	6.04e-24	102.0	COG3471@1|root,COG3471@2|Bacteria,1R3M5@1224|Proteobacteria,1S8WG@1236|Gammaproteobacteria,1Z1R0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	periplasmic secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
k59_113705_1	748658.KB907313_gene2355	1.07e-16	74.3	COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,1WZ0D@135613|Chromatiales	135613|Chromatiales	K	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
k59_113705_2	1049564.TevJSym_ah00540	4.76e-08	55.1	COG1580@1|root,COG1580@2|Bacteria,1ND67@1224|Proteobacteria,1SDZM@1236|Gammaproteobacteria,1J7DH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_13057_1	187272.Mlg_1944	1.73e-64	217.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_59559_1	653733.Selin_2283	2.39e-87	270.0	COG0499@1|root,COG0499@2|Bacteria	2|Bacteria	H	adenosylhomocysteinase activity	ahcY	GO:0000096,GO:0000097,GO:0000098,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0035375,GO:0035635,GO:0036094,GO:0036293,GO:0040007,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0070482,GO:0071268,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_201758_2	944547.ABLL_1462	2.08e-38	134.0	COG4314@1|root,COG4314@2|Bacteria,1N3G0@1224|Proteobacteria,42SNT@68525|delta/epsilon subdivisions,2YPPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_224993_1	187272.Mlg_0353	1.18e-30	126.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X102@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_217332_2	1089547.KB913013_gene3056	5.23e-25	102.0	COG0607@1|root,COG3118@1|root,COG0607@2|Bacteria,COG3118@2|Bacteria,4NUPH@976|Bacteroidetes,47PJB@768503|Cytophagia	976|Bacteroidetes	OP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
k59_232807_1	348824.LPU83_4015	4.46e-56	191.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2TU9Q@28211|Alphaproteobacteria,4BDJD@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Phospholipase D. Active site motifs.	ymdC	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_194009_1	1395571.TMS3_0113560	3.7e-23	96.3	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,1S834@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
k59_16060_1	880073.Calab_1606	5.69e-16	82.8	COG3829@1|root,COG3829@2|Bacteria,2NQFX@2323|unclassified Bacteria	2|Bacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_16060_2	926566.Terro_0989	6.18e-06	49.3	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria,2JJ2U@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_224995_1	430498.S8C3P2	1.07e-91	292.0	COG0143@1|root,KOG1247@2759|Eukaryota,38BWQ@33154|Opisthokonta,3NXU3@4751|Fungi,3QJEP@4890|Ascomycota	4751|Fungi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	MES1	GO:0002181,GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	MetRS-N,WHEP-TRS,tRNA-synt_1g
k59_31700_1	1172179.AUKV01000012_gene5517	4.43e-35	137.0	COG0654@1|root,COG0654@2|Bacteria,2I2Y3@201174|Actinobacteria	201174|Actinobacteria	CH	Tryptophan halogenase	-	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
k59_155406_1	983548.Krodi_2815	7.01e-84	263.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1HY99@117743|Flavobacteriia,37E74@326319|Dokdonia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_194010_1	697282.Mettu_1749	1.88e-54	186.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1XE6S@135618|Methylococcales	135618|Methylococcales	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
k59_224999_1	1336233.JAEH01000023_gene1900	3.54e-07	57.8	COG2202@1|root,COG3292@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3292@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q9C5@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_8,PAS_9
k59_217342_2	385682.AFSL01000073_gene1353	2.45e-16	78.6	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,2FMH3@200643|Bacteroidia,3XITX@558415|Marinilabiliaceae	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	czcA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_155415_1	378806.STAUR_4082	0.000111	51.6	COG4206@1|root,COG4206@2|Bacteria,1QX9A@1224|Proteobacteria,439E1@68525|delta/epsilon subdivisions,2X4P0@28221|Deltaproteobacteria,2YZBT@29|Myxococcales	28221|Deltaproteobacteria	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_178641_1	323261.Noc_1323	8.54e-35	129.0	2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria,1X1T1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_163097_1	395493.BegalDRAFT_1767	1.57e-32	118.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,4614X@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Rhodanese-like	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_640_1	616991.JPOO01000003_gene360	1.4e-77	234.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1HX3V@117743|Flavobacteriia,23FTI@178469|Arenibacter	976|Bacteroidetes	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
k59_640_2	313596.RB2501_14279	3.06e-88	275.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_178654_1	391587.KAOT1_19742	4.26e-21	86.7	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_178654_2	379066.GAU_3915	1.94e-15	75.1	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_70232_2	1204516.I6X7L1_9CAUD	1.41e-36	144.0	4QETB@10239|Viruses,4QZWI@35237|dsDNA viruses  no RNA stage,4QQJ2@28883|Caudovirales,4QK2X@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_217360_2	1415166.NONO_c57140	2.6e-16	79.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4FVJD@85025|Nocardiaceae	201174|Actinobacteria	E	acetolactate synthase	ilvB	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3003c	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_140024_1	316067.Geob_0549	1.78e-25	110.0	COG3829@1|root,COG4624@1|root,COG3829@2|Bacteria,COG4624@2|Bacteria,1R8T5@1224|Proteobacteria,42Q3W@68525|delta/epsilon subdivisions,2WK6C@28221|Deltaproteobacteria,43TPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Domains FehydlgC, FeS, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,HTH_8,Sigma54_activat
k59_39386_2	314345.SPV1_08761	2.89e-21	89.4	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
k59_201785_2	29760.VIT_00s0873g00020.t01	3.28e-78	233.0	COG0838@1|root,KOG4662@2759|Eukaryota,37UUF@33090|Viridiplantae,3GIT0@35493|Streptophyta	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad3	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K03880	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q4
k59_201785_3	4565.Traes_2AL_6FA19E019.1	7.25e-83	245.0	COG0048@1|root,KOG1750@2759|Eukaryota,37UKS@33090|Viridiplantae,3GIMC@35493|Streptophyta,3KZQG@4447|Liliopsida,3IH6R@38820|Poales	35493|Streptophyta	J	Rps12 protein	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_140041_1	1408473.JHXO01000006_gene1438	1.07e-10	61.6	COG4149@1|root,COG4149@2|Bacteria,4NIXK@976|Bacteroidetes,2FMCS@200643|Bacteroidia	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_140041_2	388399.SSE37_17663	1.63e-35	134.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k59_101251_1	207559.Dde_0227	7.77e-72	231.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WKNF@28221|Deltaproteobacteria,2M89B@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	carbon starvation protein	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
k59_54897_1	1183438.GKIL_4071	8.74e-08	54.7	COG0406@1|root,COG0406@2|Bacteria,1G08X@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k59_54897_2	1117647.M5M_00067	1.13e-12	67.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1J547@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iEC042_1314.EC042_2616	tRNA-synt_1c
k59_979_1	313596.RB2501_05800	1.17e-73	225.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
k59_979_2	985255.APHJ01000021_gene1593	6.86e-26	100.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia,2P5GW@244698|Gillisia	976|Bacteroidetes	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_8734_1	377629.TERTU_2234	1.31e-32	121.0	COG3177@1|root,COG3177@2|Bacteria,1RJSD@1224|Proteobacteria,1S9AR@1236|Gammaproteobacteria,2PPZP@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
k59_186666_1	272123.Anacy_0117	1.57e-21	98.2	COG4928@1|root,COG4928@2|Bacteria,1G1HK@1117|Cyanobacteria,1HKGM@1161|Nostocales	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
k59_70524_1	1406840.Q763_13980	1.87e-13	75.5	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia,2NTP2@237|Flavobacterium	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_32048_1	706587.Desti_4338	1.85e-88	270.0	COG2502@1|root,COG2502@2|Bacteria,1MVWF@1224|Proteobacteria	1224|Proteobacteria	E	aspartate--ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA,tRNA-synt_2
k59_47421_1	324602.Caur_3520	8.58e-35	132.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,Response_reg,dCache_1
k59_217662_1	63737.Npun_R2272	2.86e-21	98.6	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase
k59_55199_1	34506.g5755	1.32e-13	69.7	COG0550@1|root,KOG1956@2759|Eukaryota,39RHG@33154|Opisthokonta,3BMMR@33208|Metazoa,3DDIB@33213|Bilateria,40J8Q@6231|Nematoda,1M6UR@119089|Chromadorea,415CD@6236|Rhabditida	33208|Metazoa	L	Bacterial DNA topoisomerase I DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_55199_2	488538.SAR116_0616	1.8e-19	91.7	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,4BPAE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_132424_1	1161401.ASJA01000002_gene2633	1.88e-78	261.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,43X0I@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
k59_86082_1	981383.AEWH01000049_gene1	3.32e-20	94.7	COG3321@1|root,COG3321@2|Bacteria	2|Bacteria	Q	synthase	-	-	-	-	-	-	-	-	-	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_147900_1	301.JNHE01000001_gene299	2.25e-38	144.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1YCR4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
k59_178941_1	1123368.AUIS01000018_gene723	4.84e-79	258.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_163461_1	395493.BegalDRAFT_0878	3.21e-62	216.0	COG1196@1|root,COG4717@1|root,COG1196@2|Bacteria,COG4717@2|Bacteria,1MVAW@1224|Proteobacteria,1RZFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
k59_124695_1	86106.I862_00635	4e-26	106.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TSI2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter	nosF	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
k59_991_1	1168034.FH5T_12305	1.23e-96	294.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,2FNAX@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_233185_1	420324.KI912026_gene4855	4.92e-57	188.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,1JTW1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_240705_1	401053.AciPR4_3235	2.26e-47	159.0	COG0088@1|root,COG0088@2|Bacteria,3Y2PM@57723|Acidobacteria,2JHVM@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_240705_2	511680.BUTYVIB_01271	2.33e-14	71.2	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,4BWQQ@830|Butyrivibrio	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_1002_1	313596.RB2501_09975	3.9e-38	130.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1I1GI@117743|Flavobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_1002_2	313603.FB2170_02405	1.34e-39	133.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1I1ZW@117743|Flavobacteriia,2PHHC@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein S13/S18	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_209840_1	1168034.FH5T_11085	2.63e-104	325.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,2FPJG@200643|Bacteroidia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_86106_1	749414.SBI_01124	1.23e-15	78.2	COG1167@1|root,COG1167@2|Bacteria,2I310@201174|Actinobacteria	201174|Actinobacteria	EK	Pfam Aminotransferase class I and II	-	-	2.6.1.103	ko:K16423	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06626,R06634	RC00006,RC01104	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_101561_1	768710.DesyoDRAFT_1793	8.76e-74	251.0	COG2274@1|root,COG2274@2|Bacteria,1TRMR@1239|Firmicutes,248Z2@186801|Clostridia,261E8@186807|Peptococcaceae	186801|Clostridia	P	NHLM bacteriocin system ABC transporter, ATP-binding protein	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_16397_1	2340.JV46_18810	1.51e-128	375.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1J4WF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_147908_1	1158292.JPOE01000002_gene2613	2.02e-19	87.4	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,1KJ7J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_147908_2	1205908.AKXW01000005_gene3348	1.04e-11	70.9	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1XSGH@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	rodZ	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k59_124708_1	742766.HMPREF9455_00522	3.47e-47	169.0	COG5293@1|root,COG5293@2|Bacteria,4P0PX@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised protein conserved in bacteria (DUF2326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2326
k59_39740_1	1165841.SULAR_09759	7.47e-68	209.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2YNQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_39740_2	1165841.SULAR_09754	5.1e-12	63.9	COG3751@1|root,COG3751@2|Bacteria,1Q4MK@1224|Proteobacteria,42ZFP@68525|delta/epsilon subdivisions,2YRNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_117115_1	247490.KSU1_C1159	9.67e-54	180.0	COG2733@1|root,COG2733@2|Bacteria,2J2DM@203682|Planctomycetes	203682|Planctomycetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_117115_2	1177928.TH2_06178	3.12e-05	47.8	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,2JRR1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_78374_1	1168034.FH5T_02905	6.27e-108	327.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,2FMQC@200643|Bacteroidia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_104190_1	314285.KT71_03362	3.94e-78	236.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,1S2ZI@1236|Gammaproteobacteria,1J9P5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_3928_1	1286106.MPL1_12483	3.24e-23	94.7	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,45ZZN@72273|Thiotrichales	72273|Thiotrichales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
k59_135200_1	130081.XP_005705031.1	1.24e-171	496.0	COG0055@1|root,COG0355@1|root,KOG1350@2759|Eukaryota,KOG1758@2759|Eukaryota	2759|Eukaryota	C	proton-transporting ATP synthase activity, rotational mechanism	ATP5D	GO:0000275,GO:0002376,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005754,GO:0005756,GO:0005759,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008150,GO:0008152,GO:0008270,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009620,GO:0009628,GO:0009814,GO:0009817,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010287,GO:0010319,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016043,GO:0016310,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031976,GO:0031977,GO:0031984,GO:0032991,GO:0033178,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042221,GO:0042407,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0042776,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0044877,GO:0045087,GO:0045259,GO:0045261,GO:0045267,GO:0045269,GO:0046034,GO:0046390,GO:0046483,GO:0046688,GO:0046689,GO:0046872,GO:0046907,GO:0046914,GO:0046933,GO:0050832,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0055035,GO:0055085,GO:0055086,GO:0061024,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098542,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098807,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542	3.6.3.14	ko:K02112,ko:K02114,ko:K02133,ko:K02134,ko:K14573	ko00190,ko00195,ko01100,ko03008,ko04714,ko05010,ko05012,ko05016,map00190,map00195,map01100,map03008,map04714,map05010,map05012,map05016	M00157,M00158	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko03009	3.A.2.1	-	iMM904.YDL004W,iND750.YDL004W	ATP-synt_DE,ATP-synt_DE_N,ATP-synt_ab,ATP-synt_ab_N
k59_88803_2	653733.Selin_2538	4.04e-21	95.5	2CKMD@1|root,33DST@2|Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_50030_1	1255043.TVNIR_3409	2.35e-58	192.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1WX4Z@135613|Chromatiales	135613|Chromatiales	S	AI-2E family transporter	-	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
k59_135211_1	1165841.SULAR_00710	7.82e-101	324.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_81212_1	1165841.SULAR_06848	6.15e-114	341.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_104198_1	1168034.FH5T_16820	6.93e-106	318.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,2FP07@200643|Bacteroidia	976|Bacteroidetes	S	Ser Thr phosphatase family protein	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
k59_204833_1	1211115.ALIQ01000247_gene29	2e-100	312.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,3N9MU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_197320_1	1249627.D779_2821	3.34e-36	140.0	COG1368@1|root,COG1368@2|Bacteria,1RG6W@1224|Proteobacteria,1RY34@1236|Gammaproteobacteria,1WVXN@135613|Chromatiales	135613|Chromatiales	M	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_57792_2	1123514.KB905900_gene2196	1.49e-51	173.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,45ZS4@72273|Thiotrichales	72273|Thiotrichales	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_11503_1	272134.KB731324_gene6057	6.04e-56	188.0	COG1520@1|root,COG1520@2|Bacteria,1GDEQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
k59_81214_1	2340.JV46_09920	1.65e-49	163.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1J6UK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k59_11505_1	1168034.FH5T_20495	9.1e-89	278.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,2FPG7@200643|Bacteroidia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_158426_1	387093.SUN_0604	9.37e-100	308.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_34864_2	468059.AUHA01000003_gene1498	3.22e-41	139.0	COG0599@1|root,COG0599@2|Bacteria,4NNPC@976|Bacteroidetes,1ITG4@117747|Sphingobacteriia	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_18935_1	1168034.FH5T_07035	1.04e-78	246.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,2FPNI@200643|Bacteroidia	976|Bacteroidetes	M	3-Deoxy-D-manno-octulosonic-acid transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_73282_1	1122962.AULH01000008_gene2269	3.92e-28	113.0	28HJ1@1|root,2Z7UB@2|Bacteria,1R3FN@1224|Proteobacteria,2U1R7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_112180_1	1165841.SULAR_02958	1.59e-141	411.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,42SKY@68525|delta/epsilon subdivisions,2YR1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
k59_119903_1	1165841.SULAR_08352	8.57e-142	410.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_243542_1	1121939.L861_22400	1.17e-08	58.9	COG0607@1|root,COG0607@2|Bacteria,1NPFU@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_181792_1	1168034.FH5T_08815	2.63e-45	164.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,2G3G6@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
k59_135221_1	926556.Echvi_1013	1.94e-127	386.0	COG0783@1|root,COG3039@1|root,COG0783@2|Bacteria,COG3039@2|Bacteria,4NI06@976|Bacteroidetes,47WK3@768503|Cytophagia	976|Bacteroidetes	LP	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_42821_2	318161.Sden_0008	3.13e-13	70.1	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,2Q9QM@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378	DALR_1,tRNA_synt_2f
k59_89154_1	1250232.JQNJ01000001_gene3495	3e-114	341.0	COG1012@1|root,COG1012@2|Bacteria,4NEQ2@976|Bacteroidetes,1HYQ7@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	gapN	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_104569_1	1165841.SULAR_05968	3.67e-100	300.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,43BHX@68525|delta/epsilon subdivisions,2YMEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_166843_1	1121104.AQXH01000001_gene2201	2.48e-80	251.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,1IW6R@117747|Sphingobacteriia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
k59_50465_2	228410.NE2214	7.56e-42	146.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,37209@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
k59_243904_1	1231190.NA8A_21931	4.99e-08	62.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_213020_3	331678.Cphamn1_2139	4.06e-12	64.3	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_73760_1	472759.Nhal_3448	4.64e-119	351.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1WX6Z@135613|Chromatiales	135613|Chromatiales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_89156_1	472759.Nhal_2770	6.98e-34	130.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_4385_1	378806.STAUR_4846	5.22e-30	123.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WNBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K13611	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_174238_1	1049564.TevJSym_at00760	6.64e-94	289.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1J5F2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_182250_1	237368.SCABRO_02382	1.07e-66	229.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	spvB	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
k59_174242_1	318167.Sfri_0290	3.57e-29	120.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,2QAFC@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_27348_1	1457393.AZ09_10465	2.14e-05	45.4	COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27348_3	1556290.A0A0A0RM00_9CAUD	5.33e-131	399.0	4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae	10699|Siphoviridae	S	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_104574_1	1144275.COCOR_05973	2.19e-14	80.9	COG4403@1|root,COG4403@2|Bacteria,1R8VP@1224|Proteobacteria,432AY@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	Domain of unknown function (DUF4135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
k59_182257_1	887898.HMPREF0551_2622	1.19e-27	118.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VIYA@28216|Betaproteobacteria,1JZSG@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
k59_213026_1	1292034.OR37_01315	4.67e-28	111.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2TSP6@28211|Alphaproteobacteria,2KGH8@204458|Caulobacterales	204458|Caulobacterales	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_174248_1	1165841.SULAR_00290	3.33e-108	330.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_120309_1	4081.Solyc01g007360.2.1	3.17e-83	248.0	2CNI2@1|root,2QWGG@2759|Eukaryota,37P4I@33090|Viridiplantae,3GGGH@35493|Streptophyta,44MN2@71274|asterids	35493|Streptophyta	S	Ycf4	ycf4	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016043,GO:0019684,GO:0022607,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048564,GO:0051082,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Ycf4
k59_50477_1	387093.SUN_1168	1.46e-89	278.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_220884_1	1165841.SULAR_08749	3.87e-107	325.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_42853_1	1150469.RSPPHO_01492	2.33e-19	90.9	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,2JQFF@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k59_128133_2	1429851.X548_16655	1.26e-25	99.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1X6FE@135614|Xanthomonadales	135614|Xanthomonadales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k59_35268_1	1168034.FH5T_17585	1.75e-68	228.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,2FW70@200643|Bacteroidia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166866_1	1168034.FH5T_05140	1.43e-86	259.0	COG4912@1|root,COG4912@2|Bacteria,4NUAZ@976|Bacteroidetes,2FQ8F@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_197792_1	765911.Thivi_3343	2.59e-72	228.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1WWQU@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k59_166878_1	665959.HMPREF1013_03598	4.2e-13	74.3	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,1ZF5T@1386|Bacillus	91061|Bacilli	C	4Fe-4S double cluster binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
k59_112554_1	998674.ATTE01000001_gene216	1.07e-42	149.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,45ZNY@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_27399_1	1382359.JIAL01000001_gene2795	3.11e-42	154.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_73782_1	595460.RRSWK_03509	3.34e-40	142.0	COG4798@1|root,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
k59_58209_2	2340.JV46_06310	3.85e-125	362.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1J5TA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	iSFxv_1172.SFxv_3035	SurE
k59_4415_1	45351.EDO48022	1.31e-08	60.8	COG2103@1|root,2QS2J@2759|Eukaryota,38ECQ@33154|Opisthokonta,3BF6B@33208|Metazoa	33208|Metazoa	S	negative regulation of glucokinase activity	GCKR	GO:0000060,GO:0001678,GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006109,GO:0006110,GO:0006140,GO:0006606,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008150,GO:0008152,GO:0009593,GO:0009730,GO:0009732,GO:0009743,GO:0009746,GO:0009749,GO:0009750,GO:0009889,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010033,GO:0010562,GO:0010563,GO:0010675,GO:0010676,GO:0010677,GO:0010906,GO:0015031,GO:0015833,GO:0017038,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019725,GO:0019899,GO:0019904,GO:0030234,GO:0030246,GO:0030808,GO:0030811,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031329,GO:0031974,GO:0031981,GO:0033036,GO:0033131,GO:0033132,GO:0033133,GO:0033365,GO:0033500,GO:0033673,GO:0033674,GO:0034284,GO:0034287,GO:0034504,GO:0034613,GO:0034641,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042592,GO:0042593,GO:0042886,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043467,GO:0043470,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045912,GO:0045913,GO:0045936,GO:0045937,GO:0046415,GO:0046483,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051169,GO:0051170,GO:0051171,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051234,GO:0051338,GO:0051347,GO:0051348,GO:0051594,GO:0051606,GO:0051641,GO:0051649,GO:0055082,GO:0055088,GO:0055090,GO:0062012,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070095,GO:0070328,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0072521,GO:0072594,GO:0080090,GO:0097367,GO:0098772,GO:1900371,GO:1900542,GO:1901360,GO:1901564,GO:1901700,GO:1903299,GO:1903300,GO:1903301,GO:1903578,GO:2001169	-	-	-	-	-	-	-	-	-	-	-
k59_128138_1	998674.ATTE01000001_gene493	9.1e-55	186.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,45ZP3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_166884_1	879212.DespoDRAFT_01754	2.2e-48	161.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K16137,ko:K18476	-	M00668	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N,TniQ
k59_11941_1	391603.FBALC1_01012	2.3e-37	142.0	COG1629@1|root,COG1629@2|Bacteria,4PM9F@976|Bacteroidetes,1HZ8T@117743|Flavobacteriia	976|Bacteroidetes	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213054_1	1463934.JOCF01000072_gene5872	1.26e-08	60.1	COG2267@1|root,COG2267@2|Bacteria,2I2IM@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_135674_1	1165841.SULAR_00370	6.04e-42	149.0	COG0790@1|root,COG0790@2|Bacteria,1Q4TH@1224|Proteobacteria,42ZV8@68525|delta/epsilon subdivisions,2YRWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_37688_1	1380600.AUYN01000001_gene2563	4.21e-59	196.0	COG2017@1|root,COG2017@2|Bacteria,4NE32@976|Bacteroidetes,1HYM4@117743|Flavobacteriia	976|Bacteroidetes	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76275_1	485915.Dret_1500	7.04e-90	270.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2MGH2@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_99478_1	1296415.JACC01000001_gene3573	4.01e-50	167.0	2DUKC@1|root,33R3H@2|Bacteria,4P0Z8@976|Bacteroidetes,1I85Z@117743|Flavobacteriia,2YKDG@290174|Aquimarina	976|Bacteroidetes	S	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
k59_52798_1	545276.KB898729_gene1639	2.49e-73	236.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_230637_1	112098.XP_008605165.1	1.77e-70	228.0	COG0015@1|root,KOG2700@2759|Eukaryota	2759|Eukaryota	F	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	ADSL	GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006106,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007584,GO:0008150,GO:0008152,GO:0009058,GO:0009060,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009605,GO:0009987,GO:0009991,GO:0015980,GO:0016043,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031667,GO:0034641,GO:0034654,GO:0042221,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0050896,GO:0051259,GO:0051262,GO:0055086,GO:0055114,GO:0065003,GO:0070626,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_45164_1	1131269.AQVV01000005_gene377	1.31e-38	144.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_106907_1	1288826.MSNKSG1_00541	1.53e-35	127.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_106907_2	1288826.MSNKSG1_00546	7.79e-42	139.0	2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
k59_106907_3	1415778.JQMM01000001_gene2176	1.88e-31	114.0	COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	epsilon subunit	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k59_146285_1	1250232.JQNJ01000001_gene2331	3.06e-68	207.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1I1ZH@117743|Flavobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_146285_2	1121011.AUCB01000016_gene3990	5.36e-14	70.1	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1HZU1@117743|Flavobacteriia,23G47@178469|Arenibacter	976|Bacteroidetes	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_176551_1	391603.FBALC1_14727	9.19e-62	198.0	COG5309@1|root,COG5309@2|Bacteria,4NIVF@976|Bacteroidetes,1I014@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
k59_176551_2	313595.P700755_003222	1.62e-13	68.9	COG2211@1|root,COG5309@1|root,COG2211@2|Bacteria,COG5309@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia,4C36I@83612|Psychroflexus	976|Bacteroidetes	G	Glycosyl hydrolases family 17	uidB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
k59_153392_1	604331.AUHY01000012_gene2724	2.39e-50	169.0	COG1131@1|root,COG1131@2|Bacteria,1WK7Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_207582_1	1122176.KB903543_gene685	3.49e-83	259.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_169371_1	395493.BegalDRAFT_0076	4.96e-36	133.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S1WE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_207585_1	1408473.JHXO01000008_gene2732	2.27e-25	106.0	2A7CK@1|root,30W9H@2|Bacteria,4P9NF@976|Bacteroidetes,2FV4R@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215338_1	1249975.JQLP01000003_gene260	8.74e-94	282.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1HY7R@117743|Flavobacteriia,2P61T@244698|Gillisia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_14400_3	1217656.F964_03501	6.89e-07	53.9	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,3NJ2A@468|Moraxellaceae	1236|Gammaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_130796_1	1165841.SULAR_06008	1.39e-70	219.0	COG4244@1|root,COG4244@2|Bacteria,1PJNV@1224|Proteobacteria,42TI9@68525|delta/epsilon subdivisions,2YQ43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146725_1	1165841.SULAR_04167	2.86e-74	235.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_146725_2	1165841.SULAR_04172	2.24e-157	457.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_246613_1	159087.Daro_0999	4.5e-28	107.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,2KWZ1@206389|Rhodocyclales	206389|Rhodocyclales	S	Invasion gene expression up-regulator SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
k59_192661_1	765911.Thivi_2767	7.33e-76	238.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WWA8@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_130799_1	2340.JV46_08510	1.35e-50	161.0	2CDMX@1|root,32S1K@2|Bacteria,1N1I8@1224|Proteobacteria,1S9N4@1236|Gammaproteobacteria,1JB6N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130799_2	998674.ATTE01000001_gene2740	1.59e-12	69.3	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales	72273|Thiotrichales	L	Exonuclease C-terminal	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k59_146739_1	1165841.SULAR_06738	2.61e-99	309.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42Z4X@68525|delta/epsilon subdivisions,2YRD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_30233_2	301.JNHE01000023_gene2547	2.7e-15	77.4	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria,1YE3V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
k59_208021_1	1173026.Glo7428_1788	3.54e-45	150.0	COG1569@1|root,COG1569@2|Bacteria,1G5T4@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxin-antitoxin system, toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_208021_2	1298865.H978DRAFT_2952	2.52e-32	113.0	2C16Q@1|root,330H3@2|Bacteria,1NB82@1224|Proteobacteria,1SERQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
k59_161615_1	1120951.AUBG01000006_gene530	6.43e-96	288.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,1HXI9@117743|Flavobacteriia	976|Bacteroidetes	S	Dehydrogenase	-	-	1.1.1.1	ko:K12957,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_91829_1	1168034.FH5T_07175	8.59e-79	256.0	COG0363@1|root,COG0363@2|Bacteria,4NDUN@976|Bacteroidetes,2FM2W@200643|Bacteroidia	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_176921_1	395493.BegalDRAFT_3248	6.13e-57	186.0	2DDRX@1|root,2ZJ18@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_230996_1	1168034.FH5T_10605	2.37e-33	125.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_230996_2	1122978.AUFP01000006_gene1662	1.29e-06	50.8	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_246635_1	2340.JV46_08230	1.72e-119	356.0	COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,1RYGW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_61080_1	3880.AES66713	6.92e-34	119.0	2E8XP@1|root,2SFC6@2759|Eukaryota,37XVB@33090|Viridiplantae,3GMRR@35493|Streptophyta,4JV96@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215712_1	2340.JV46_09500	3.89e-96	305.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1J5MR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Pyruvate phosphate dikinase	ppdK	-	2.7.3.9,2.7.9.1,2.7.9.2	ko:K01006,ko:K01007,ko:K08483	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00710,map00720,map01100,map01120,map01200,map02060	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_99921_2	1123326.JFBL01000004_gene2135	1.54e-80	241.0	293MU@1|root,2ZR3M@2|Bacteria,1REEY@1224|Proteobacteria	1224|Proteobacteria	S	Superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
k59_215714_1	1296415.JACC01000014_gene984	6.78e-57	197.0	COG0739@1|root,COG2273@1|root,COG3401@1|root,COG0739@2|Bacteria,COG2273@2|Bacteria,COG3401@2|Bacteria,4P1G2@976|Bacteroidetes,1I78P@117743|Flavobacteriia,2YKT3@290174|Aquimarina	976|Bacteroidetes	G	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239081_1	933262.AXAM01000009_gene1485	1.17e-38	136.0	COG0727@1|root,COG0727@2|Bacteria,1Q0JM@1224|Proteobacteria,42N6S@68525|delta/epsilon subdivisions,2WMTR@28221|Deltaproteobacteria,2MIXY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_239081_2	933262.AXAM01000009_gene1486	1.31e-38	136.0	COG1028@1|root,COG1028@2|Bacteria,1R7KW@1224|Proteobacteria,42NF5@68525|delta/epsilon subdivisions,2WM4D@28221|Deltaproteobacteria,2MIF5@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_169727_1	1279017.AQYJ01000028_gene2405	1.98e-68	226.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_200537_1	387093.SUN_0018	3.75e-24	100.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2YMGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_200537_2	1165841.SULAR_08587	3.36e-81	244.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42THH@68525|delta/epsilon subdivisions,2YQ14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_200537_3	1165841.SULAR_08592	4.97e-14	69.7	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,42Y1W@68525|delta/epsilon subdivisions,2YQU0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6969_1	1165841.SULAR_04547	1.62e-42	143.0	COG1309@1|root,COG1309@2|Bacteria,1PFK7@1224|Proteobacteria,42UZC@68525|delta/epsilon subdivisions,2YQ5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N
k59_6969_2	1165841.SULAR_04552	9.04e-23	93.6	COG0671@1|root,COG0671@2|Bacteria,1QV0A@1224|Proteobacteria,43BVB@68525|delta/epsilon subdivisions,2YTA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_68865_1	1233488.S4T7A1_9CAUD	3.6e-26	103.0	4QEW9@10239|Viruses,4QWFV@35237|dsDNA viruses  no RNA stage,4QRGP@28883|Caudovirales,4QNCN@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_246642_1	1192034.CAP_7989	5.51e-19	93.6	COG0500@1|root,COG5439@1|root,COG2226@2|Bacteria,COG5439@2|Bacteria,1R98E@1224|Proteobacteria,43847@68525|delta/epsilon subdivisions,2X3E4@28221|Deltaproteobacteria,2YVN5@29|Myxococcales	28221|Deltaproteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_45558_1	1267535.KB906767_gene753	2.26e-141	410.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_130812_1	1165841.SULAR_09489	3.16e-118	344.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,42MVH@68525|delta/epsilon subdivisions	1224|Proteobacteria	HJ	Sugar-transfer associated ATP-grasp	PA1766	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
k59_130812_2	1165841.SULAR_09479	1.7e-43	149.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_153801_1	1030157.AFMP01000045_gene1646	4.16e-32	123.0	COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,2U1U3@28211|Alphaproteobacteria,2K2BQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_200541_1	1165841.SULAR_01360	7.3e-116	359.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_223614_1	291985.CCSI01000003_gene135	2.37e-10	63.9	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,2K57J@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_6983_1	338966.Ppro_0084	2.29e-28	122.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,43T8P@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
k59_130820_1	1177181.T9A_00317	7.96e-38	137.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1XI26@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_115222_1	395493.BegalDRAFT_0896	4.97e-42	142.0	COG0245@1|root,COG0245@2|Bacteria,1NY73@1224|Proteobacteria,1SQY1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
k59_115222_2	472759.Nhal_2681	1.51e-59	192.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1WXHT@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
k59_146787_1	1168034.FH5T_10710	1.07e-69	223.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,2FM98@200643|Bacteroidia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_239093_1	272134.KB731324_gene3814	8.2e-11	62.4	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_99958_1	870187.Thini_2499	1.05e-61	211.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales	72273|Thiotrichales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_138286_1	1165841.SULAR_03657	4.62e-125	380.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_146793_1	596154.Alide2_4327	1.77e-44	157.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,4AB9E@80864|Comamonadaceae	28216|Betaproteobacteria	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	coxI	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_123230_3	2340.JV46_02720	2.06e-63	212.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	2.7.11.1	ko:K03546,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko03400	-	-	-	AAA_23,Pkinase,SMC_N
k59_6988_1	395493.BegalDRAFT_3518	2.65e-68	218.0	COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,1RNGH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_123233_1	1165841.SULAR_02313	5.45e-36	128.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2YP7U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
k59_123233_2	1165841.SULAR_02318	7.86e-44	145.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42VVX@68525|delta/epsilon subdivisions,2YQGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_48772_1	313596.RB2501_06875	7.08e-110	322.0	COG3064@1|root,COG3064@2|Bacteria,4NESI@976|Bacteroidetes,1HXS4@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_180387_1	247634.GPB2148_3470	4.33e-34	130.0	COG2188@1|root,COG2188@2|Bacteria,1QVF7@1224|Proteobacteria,1S5D3@1236|Gammaproteobacteria,1J8FY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative porin	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Porin_5
k59_180387_2	745014.OMB55_00008200	5.05e-06	47.8	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1J530@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	FP	Belongs to the GppA Ppx family	gppA	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643	HD,Ppx-GppA
k59_56507_1	1123401.JHYQ01000008_gene434	5.32e-18	84.3	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462DX@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_56507_2	314265.R2601_09757	2.44e-35	131.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,2U20B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Mg2 transporter protein, CorA family protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k59_157064_1	2340.JV46_05960	4.88e-105	331.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
k59_102901_1	1380393.JHVP01000003_gene789	9.02e-19	92.4	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,4ERHE@85013|Frankiales	201174|Actinobacteria	C	BFD domain protein 2Fe-2S -binding domain protein	nasD	-	1.7.1.15	ko:K00360,ko:K00362	ko00910,ko01120,map00910,map01120	M00530,M00531	R00787,R00798	RC00176,RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_102901_2	1121935.AQXX01000142_gene2322	2.26e-08	51.6	2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,1SCYA@1236|Gammaproteobacteria,1XM1Y@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF5062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5062
k59_17668_1	2340.JV46_03820	4.65e-174	509.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1J4XS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_2673	ACT_4,HD_4,RelA_SpoT,TGS
k59_234649_1	1168034.FH5T_04250	2.76e-72	239.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein, OMP85 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_87413_1	2340.JV46_23100	5.59e-37	130.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1J51I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394	Aminotran_4
k59_87413_2	768671.ThimaDRAFT_3757	1.63e-09	58.5	COG0421@1|root,COG0421@2|Bacteria,1QZ2Z@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95307_1	1165841.SULAR_09579	2.65e-145	412.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,42MHJ@68525|delta/epsilon subdivisions,2YMM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	dinuclear metal center protein, YbgI	-	-	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
k59_64278_2	1081640.AGFU01000048_gene657	0.00051	47.4	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2U7P9@28211|Alphaproteobacteria,2K40J@204457|Sphingomonadales	204457|Sphingomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_203541_1	478741.JAFS01000002_gene787	8.68e-05	43.9	COG1690@1|root,COG1690@2|Bacteria,46STD@74201|Verrucomicrobia,37FUV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_203541_2	1121377.KB906399_gene1501	2.36e-08	57.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyrid_ox_like
k59_71913_2	1165841.SULAR_03562	9.37e-50	159.0	COG1550@1|root,COG1550@2|Bacteria,1Q2MJ@1224|Proteobacteria,42VYB@68525|delta/epsilon subdivisions,2YQ9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k59_149304_1	1165841.SULAR_06803	2.88e-106	312.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2YMP6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_56511_2	929703.KE386491_gene952	1.59e-19	86.7	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN,Tox-MPTase2
k59_203543_1	631362.Thi970DRAFT_04125	1.22e-65	226.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWSZ@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_110694_1	1279017.AQYJ01000021_gene2879	3.64e-60	204.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,469GD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_17682_1	1121396.KB892902_gene2267	4.85e-41	149.0	COG3023@1|root,COG3023@2|Bacteria,1PD4C@1224|Proteobacteria,42PQW@68525|delta/epsilon subdivisions,2WK9V@28221|Deltaproteobacteria,2MI3K@213118|Desulfobacterales	28221|Deltaproteobacteria	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
k59_219063_1	880073.Calab_0209	3.52e-25	108.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	-	-	1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13	ko:K00123,ko:K00317,ko:K00528,ko:K09835	ko00630,ko00680,ko00906,ko01100,ko01110,ko01120,ko01200,map00630,map00680,map00906,map01100,map01110,map01120,map01200	M00097	R00519,R01588,R02511,R07512,R10159	RC00185,RC00556,RC00557,RC00732,RC01960,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4_20,NAD_binding_8,Oxidored_FMN,Pyr_redox_2
k59_126296_1	1499967.BAYZ01000061_gene5966	4.91e-37	143.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	wspE	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3,2.7.7.65	ko:K03407,ko:K11444,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_133893_1	2340.JV46_29040	1.68e-93	288.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1J4T7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iPC815.YPO3762,iSFV_1184.SFV_3651	TrkH
k59_25621_1	880073.Calab_2761	9.45e-31	120.0	COG3547@1|root,COG3547@2|Bacteria,2NPVY@2323|unclassified Bacteria	2|Bacteria	L	COGs COG3547 Transposase and inactivated derivatives	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_203545_1	1123400.KB904791_gene108	2.48e-61	197.0	COG2162@1|root,COG2162@2|Bacteria,1RDF3@1224|Proteobacteria,1RQTF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Belongs to the arylamine N-acetyltransferase family	nhoA	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
k59_87431_1	1168034.FH5T_21890	3.11e-123	368.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia	976|Bacteroidetes	C	2-oxoacid acceptor oxidoreductase, alpha subunit	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_33620_2	2340.JV46_09760	1.07e-73	223.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1J5PF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_188113_1	566466.NOR53_3542	1.84e-61	205.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1J5DY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_56529_1	1174528.JH992898_gene5145	1.37e-17	86.3	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,1JHAR@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_149316_1	395493.BegalDRAFT_2393	1.43e-97	293.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,45ZRA@72273|Thiotrichales	72273|Thiotrichales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_25634_1	1168034.FH5T_01470	3.65e-56	187.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FWYQ@200643|Bacteroidia	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k59_164963_1	1437882.AZRU01000043_gene4837	1.45e-09	62.8	28IZ5@1|root,2Z8WP@2|Bacteria,1R6WI@1224|Proteobacteria,1S87I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_110711_1	1198452.Jab_2c32740	5.27e-17	79.7	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,472KE@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_110711_2	1123393.KB891316_gene1806	9.46e-10	57.8	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,1KSVR@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_41207_1	1123355.JHYO01000016_gene1859	1.68e-109	325.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,37091@31993|Methylocystaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_188124_2	1163409.UUA_08029	4.62e-21	95.9	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales	135614|Xanthomonadales	T	Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_149327_1	2340.JV46_21990	4.93e-102	306.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1J4HP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Phosphoenolpyruvate phosphomutase	aceA	GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b4015,iAF1260.b4015,iB21_1397.B21_03847,iBWG_1329.BWG_3671,iE2348C_1286.E2348C_4318,iEC042_1314.EC042_4377,iEC55989_1330.EC55989_4500,iECABU_c1320.ECABU_c45310,iECBD_1354.ECBD_4022,iECB_1328.ECB_03887,iECDH10B_1368.ECDH10B_4204,iECDH1ME8569_1439.ECDH1ME8569_3871,iECD_1391.ECD_03887,iECED1_1282.ECED1_4722,iECIAI1_1343.ECIAI1_4235,iECIAI39_1322.ECIAI39_4401,iECNA114_1301.ECNA114_4164,iECO103_1326.ECO103_4759,iECO111_1330.ECO111_4827,iECO26_1355.ECO26_5119,iECP_1309.ECP_4225,iECSE_1348.ECSE_4300,iECSF_1327.ECSF_3865,iECUMN_1333.ECUMN_4541,iECW_1372.ECW_m4374,iEKO11_1354.EKO11_4310,iETEC_1333.ETEC_4270,iEcDH1_1363.EcDH1_3982,iEcE24377_1341.EcE24377A_4557,iEcHS_1320.EcHS_A4249,iEcSMS35_1347.EcSMS35_4469,iEcolC_1368.EcolC_4015,iJN746.PP_4116,iJO1366.b4015,iJR904.b4015,iLF82_1304.LF82_0012,iNRG857_1313.NRG857_20015,iSDY_1059.SDY_4328,iUMNK88_1353.UMNK88_4859,iWFL_1372.ECW_m4374,iY75_1357.Y75_RS20880	ICL
k59_195952_1	1165841.SULAR_08804	1.26e-146	428.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2YMVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_64295_1	3827.XP_004516189.1	0.0	1095.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,4JSMX@91835|fabids	35493|Streptophyta	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_242272_1	1168034.FH5T_05795	1.95e-116	367.0	COG3250@1|root,COG3250@2|Bacteria,4NKZX@976|Bacteroidetes,2FNTC@200643|Bacteroidia	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
k59_2553_1	387093.SUN_0532	7.85e-49	174.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,43CM6@68525|delta/epsilon subdivisions,2YTE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_41220_1	886377.Murru_1510	2.13e-24	98.2	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_41220_2	313596.RB2501_05825	9.36e-06	45.4	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia	976|Bacteroidetes	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_226677_1	2340.JV46_15410	1.72e-137	399.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_226677_2	2340.JV46_15420	8.57e-44	148.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
k59_33652_1	1168034.FH5T_12670	3.15e-91	280.0	COG3291@1|root,COG3291@2|Bacteria,4NU2U@976|Bacteroidetes,2FNZM@200643|Bacteroidia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_56819_1	880073.Calab_0346	9.84e-83	256.0	COG0002@1|root,COG0002@2|Bacteria,2NNN5@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the NAGSA dehydrogenase family. Type 1 subfamily	argC	-	1.2.1.38	ko:K00145,ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00028,M00031,M00763,M00845	R03443,R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_165345_1	1408473.JHXO01000008_gene2790	1.3e-44	161.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,2FMXI@200643|Bacteroidia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase C-terminal	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_196304_1	338963.Pcar_0655	8.96e-42	147.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,43S2S@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_196304_2	1131269.AQVV01000006_gene465	4.25e-18	92.4	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
k59_2901_2	1236541.BALL01000017_gene2383	4.04e-09	59.3	COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,1S8XS@1236|Gammaproteobacteria,2QA1X@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	carbon utilization	mshJ	-	-	ko:K12280	-	-	-	-	ko00000,ko02044	-	-	-	PilO,T2SSM
k59_134198_1	445686.E3SL62_9CAUD	4.47e-88	280.0	4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses  no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage T4-like capsid assembly protein (Gp20)	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_149655_1	1168034.FH5T_11060	1.05e-70	233.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_234997_1	1223523.H340_23763	2.17e-31	127.0	COG1376@1|root,COG2304@1|root,COG1376@2|Bacteria,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
k59_126649_1	626887.J057_10046	3.02e-38	133.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,467CR@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	NnrU protein	nnrU	-	-	-	-	-	-	-	-	-	-	-	NnrU
k59_49098_1	1172190.M947_08615	3.87e-86	265.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_157446_1	1168034.FH5T_09260	3.98e-63	204.0	COG2897@1|root,COG2897@2|Bacteria,4NKP3@976|Bacteroidetes	976|Bacteroidetes	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_56828_1	237368.SCABRO_03144	1.69e-15	82.0	COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_219412_1	1121405.dsmv_3062	4.08e-69	230.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,2MJ0A@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_72301_1	207954.MED92_06931	1.21e-19	90.1	COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1RPFY@1236|Gammaproteobacteria,1XRSW@135619|Oceanospirillales	135619|Oceanospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07637	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
k59_172951_1	243090.RB5029	1.16e-17	80.9	COG4798@1|root,COG4798@2|Bacteria,2IYU0@203682|Planctomycetes	203682|Planctomycetes	S	COG2226 Methylase involved in ubiquinone menaquinone	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_172951_2	1392488.JHZY01000002_gene739	3.49e-69	217.0	COG1305@1|root,COG1305@2|Bacteria,4NHV0@976|Bacteroidetes,1I7DH@117743|Flavobacteriia	976|Bacteroidetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_111064_1	653045.Strvi_5196	4.57e-44	166.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_56832_1	1415754.JQMK01000005_gene1767	9.13e-82	247.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_103253_1	1123392.AQWL01000021_gene2157	5.86e-06	53.5	COG1305@1|root,COG3209@1|root,COG1305@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2W9ZD@28216|Betaproteobacteria,1KSCA@119069|Hydrogenophilales	119069|Hydrogenophilales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_172954_1	222891.NSE_0423	2.12e-26	113.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,47F48@766|Rickettsiales	766|Rickettsiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_87781_2	313596.RB2501_01011	2.28e-45	163.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_157451_2	1134445.AJJM01000007_gene3145	5.75e-52	176.0	COG0160@1|root,COG0160@2|Bacteria,2GKUY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_196323_1	1223410.KN050846_gene397	1.01e-50	171.0	2E3AK@1|root,2ZCCU@2|Bacteria,4NN6G@976|Bacteroidetes,1I1MB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80179_1	1165841.SULAR_06968	2.54e-139	402.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_142048_1	292415.Tbd_0827	2.64e-51	178.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VK3W@28216|Betaproteobacteria,1KSG7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_191032_2	1173028.ANKO01000164_gene2744	2.75e-44	153.0	COG1073@1|root,COG1073@2|Bacteria,1G2EP@1117|Cyanobacteria,1H83Z@1150|Oscillatoriales	1117|Cyanobacteria	S	of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
k59_245040_1	1131553.JIBI01000017_gene577	3.82e-59	206.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase recycling family C-terminal	-	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N
k59_136672_1	13333.ERN02870	8.79e-204	566.0	2CMAK@1|root,2QPT8@2759|Eukaryota,37MKA@33090|Viridiplantae,3GD5I@35493|Streptophyta	35493|Streptophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N,CemA
k59_12835_1	1165841.SULAR_08382	1.1e-164	479.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2YMJN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
k59_136673_1	96561.Dole_3250	1.54e-88	273.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_183275_1	1165841.SULAR_07153	5.85e-102	324.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2YSXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
k59_152182_1	1165841.SULAR_02808	6.18e-137	405.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_152182_2	1165841.SULAR_02813	1.79e-93	281.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_105562_1	1165841.SULAR_09054	1.49e-21	92.4	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_90168_1	96561.Dole_3058	1.6e-25	108.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MI4U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_113516_1	1165841.SULAR_07093	5.66e-123	356.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2YMV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_175254_1	1189612.A33Q_1078	8.87e-16	81.6	COG2972@1|root,COG2972@2|Bacteria,4NRRA@976|Bacteroidetes,47V23@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_136679_1	283942.IL1746	1.47e-30	114.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,2QF47@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Belongs to the SUA5 family	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_43941_1	1049564.TevJSym_aj00810	8.82e-108	336.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	ttrA	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K08357,ko:K21307	ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020	-	R10149,R10150,R11487	RC00168,RC02823,RC03109	ko00000,ko00001,ko01000,ko02000	5.A.3.10,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_12843_1	562970.Btus_1053	1.61e-48	174.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,27812@186823|Alicyclobacillaceae	91061|Bacilli	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_144997_1	88036.EFJ05008	1.26e-50	172.0	28ISP@1|root,2QR3X@2759|Eukaryota,37T53@33090|Viridiplantae,3G7SE@35493|Streptophyta	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbC	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_144997_2	4565.Traes_2AL_6C270714E1.1	7.43e-38	128.0	2C06H@1|root,2S7KE@2759|Eukaryota,37X2N@33090|Viridiplantae,3GM7I@35493|Streptophyta	35493|Streptophyta	S	Photosystem II reaction center protein Z	psbZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02724	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	Ycf9
k59_144997_3	4155.Migut.J01359.1.p	1.77e-60	186.0	COG0199@1|root,KOG1741@2759|Eukaryota,37VQM@33090|Viridiplantae,3GJZT@35493|Streptophyta	35493|Streptophyta	J	Binds 16S rRNA, required for the assembly of 30S particles	rps14	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_144997_4	4155.Migut.J01360.1.p	0.0	1520.0	28JJ8@1|root,2QRYE@2759|Eukaryota,37QY5@33090|Viridiplantae,3GH5Y@35493|Streptophyta,44Q5F@71274|asterids	35493|Streptophyta	C	Photosystem I psaA/psaB protein	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016168,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k59_144997_5	50452.W0USV0	0.0	1526.0	28JJ8@1|root,2QRYE@2759|Eukaryota,37RH7@33090|Viridiplantae,3GCW8@35493|Streptophyta,3I0SM@3699|Brassicales	35493|Streptophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0009987,GO:0010287,GO:0015979,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02689	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k59_144997_6	72664.XP_006404497.1	3.24e-49	158.0	COG0457@1|root,KOG1124@2759|Eukaryota,37TZH@33090|Viridiplantae,3GKZ9@35493|Streptophyta	35493|Streptophyta	S	Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits	ycf3	-	-	-	-	-	-	-	-	-	-	-	TPR_1
k59_144997_9	4155.Migut.D01426.1.p	2.61e-131	374.0	COG0522@1|root,KOG3301@2759|Eukaryota,37TGK@33090|Viridiplantae,3G7BN@35493|Streptophyta,44PVZ@71274|asterids	35493|Streptophyta	J	Ribosomal protein S4/S9 N-terminal domain	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_144997_10	3880.AES88239	2.79e-10	60.1	COG0522@1|root,KOG3301@2759|Eukaryota,37TGK@33090|Viridiplantae,3G7BN@35493|Streptophyta	35493|Streptophyta	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_144997_11	4155.Migut.D01427.1.p	1.5e-118	338.0	COG0852@1|root,KOG1713@2759|Eukaryota,37QGD@33090|Viridiplantae,3GGF5@35493|Streptophyta,44PBS@71274|asterids	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	ndhJ	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K05581	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_30kDa
k59_144997_12	4155.Migut.D01428.1.p	5.34e-154	435.0	COG0377@1|root,KOG1687@2759|Eukaryota,37QTD@33090|Viridiplantae,3GHED@35493|Streptophyta,44RGU@71274|asterids	35493|Streptophyta	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	ndhK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3	ko:K05582	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q6
k59_144997_13	3847.GLYMA13G04690.2	1.06e-72	219.0	COG0838@1|root,KOG4662@2759|Eukaryota,37UN0@33090|Viridiplantae,3GISB@35493|Streptophyta,4JUVD@91835|fabids	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008137,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
k59_82484_1	1165841.SULAR_00415	7.23e-108	316.0	COG1651@1|root,COG1651@2|Bacteria,1RFRJ@1224|Proteobacteria,42SPD@68525|delta/epsilon subdivisions,2YP88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_221929_1	1165841.SULAR_01305	3.96e-34	119.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2YT6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	DnaK suppressor protein	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_221929_2	1165841.SULAR_01310	1.31e-41	145.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YQ1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36445_1	686578.AFFX01000001_gene1411	6.36e-39	142.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,1S3FP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_105566_1	1313421.JHBV01000039_gene2599	1.73e-08	62.8	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IR5G@117747|Sphingobacteriia	976|Bacteroidetes	KT	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
k59_245052_1	1168034.FH5T_21950	9.45e-67	210.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,2FMTM@200643|Bacteroidia	976|Bacteroidetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_183290_1	471852.Tcur_4321	5.01e-55	179.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4EIEQ@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_183290_2	401053.AciPR4_3237	1.83e-47	154.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_129108_1	1185876.BN8_01275	6.7e-111	340.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_214150_1	1165841.SULAR_09179	9.14e-162	477.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07648,ko:K07679	ko02020,ko02026,ko05133,map02020,map02026,map05133	M00456,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF_2,HATPase_c,HisKA,Hpt,PAS,Response_reg
k59_245053_1	1168034.FH5T_04825	9.13e-105	317.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia	976|Bacteroidetes	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_245054_1	631362.Thi970DRAFT_02781	6.8e-26	106.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1WW01@135613|Chromatiales	135613|Chromatiales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_183298_1	1121129.KB903367_gene2846	4.34e-24	93.6	2E8AK@1|root,332PF@2|Bacteria,4NVH4@976|Bacteroidetes,2FVCD@200643|Bacteroidia,230P9@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_183298_2	1259795.ARJK01000005_gene1301	1.57e-05	45.8	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,42GT2@68295|Thermoanaerobacterales	186801|Clostridia	KT	Phage shock protein C, PspC	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
k59_74961_1	1168034.FH5T_12465	6.3e-116	335.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,2FNHP@200643|Bacteroidia	976|Bacteroidetes	K	Cyclic nucleotide-binding domain protein	-	-	-	ko:K21556	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_13186_1	1121346.KB899827_gene490	3.73e-82	260.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,26R94@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_237737_1	1283076.M1IP93_9CAUD	1.54e-122	379.0	4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses  no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae	10662|Myoviridae	S	Phage tail sheath protein	-	GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027	-	-	-	-	-	-	-	-	-	-	-
k59_183666_1	1296415.JACC01000105_gene2891	3.72e-184	518.0	COG3328@1|root,COG3328@2|Bacteria,4NFQS@976|Bacteroidetes,1HZYN@117743|Flavobacteriia,2YJXM@290174|Aquimarina	976|Bacteroidetes	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_90560_1	493475.GARC_4265	1.32e-22	109.0	COG2931@1|root,COG2982@1|root,COG4733@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG4733@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
k59_152515_1	1165841.SULAR_01558	4.4e-156	446.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2YTP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_75336_1	1192034.CAP_4580	1.06e-26	114.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1MX27@1224|Proteobacteria	1224|Proteobacteria	TV	ABC-type multidrug transport system ATPase component	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
k59_222302_1	526225.Gobs_2600	2.84e-27	112.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4ETY1@85013|Frankiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_59724_1	867900.Celly_0568	4.75e-24	96.3	COG0494@1|root,COG0494@2|Bacteria,4PKI3@976|Bacteroidetes,1IJ9T@117743|Flavobacteriia,1F8BW@104264|Cellulophaga	976|Bacteroidetes	L	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_59724_2	616991.JPOO01000003_gene1226	9.58e-117	338.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia,23G6W@178469|Arenibacter	976|Bacteroidetes	F	Phosphoribosyl transferase domain	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
k59_59724_3	1380600.AUYN01000009_gene1793	2.2e-09	55.8	COG3427@1|root,COG3427@2|Bacteria,4NQ8H@976|Bacteroidetes,1I307@117743|Flavobacteriia	976|Bacteroidetes	S	Orotate phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_199260_1	1165841.SULAR_01998	9.56e-113	334.0	COG0475@1|root,COG0475@2|Bacteria	2|Bacteria	P	glutathione-regulated potassium exporter activity	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Na_H_Exchanger
k59_20922_1	1121875.KB907548_gene1231	8.9e-67	218.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HWJQ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_245400_1	1301098.PKB_4083	2.91e-13	75.5	COG0697@1|root,COG0697@2|Bacteria,1N469@1224|Proteobacteria,1RQ1G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_206636_1	2340.JV46_26910	1.86e-14	78.6	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1JC0F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_222310_1	2340.JV46_13820	5.54e-25	104.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1JA45@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_98463_1	1453501.JELR01000002_gene601	1.36e-80	247.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,465E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_44290_1	1452718.JBOY01000071_gene2487	3.72e-05	45.1	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,1S1F0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k59_44290_2	1307759.JOMJ01000004_gene2542	1.71e-72	229.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MG2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_13210_1	2340.JV46_18890	5.37e-34	128.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1J7ED@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG1459 Type II secretory pathway, component PulF	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_13210_2	1122211.JMLW01000005_gene513	7.73e-10	58.5	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1XKIP@135619|Oceanospirillales	135619|Oceanospirillales	U	secretion system protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_98465_1	313612.L8106_02572	8.21e-47	162.0	COG2358@1|root,COG2358@2|Bacteria,1G9Z1@1117|Cyanobacteria,1HGV3@1150|Oscillatoriales	1117|Cyanobacteria	S	transport system, periplasmic component	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_82784_1	765913.ThidrDRAFT_2335	2.38e-24	111.0	COG1262@1|root,COG1262@2|Bacteria,1PGVZ@1224|Proteobacteria,1SM2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_183687_1	1165841.SULAR_10689	1.19e-112	334.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42PRR@68525|delta/epsilon subdivisions,2YMYP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	sulfur dehydrogenase subunit	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_51972_1	1283300.ATXB01000001_gene1995	2.04e-25	109.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1XF1D@135618|Methylococcales	135618|Methylococcales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_168347_5	4081.Solyc00g013160.1.1	2.53e-10	58.2	2D0J1@1|root,2SEDM@2759|Eukaryota,37XX0@33090|Viridiplantae,3GMNP@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44295_1	857087.Metme_4078	1.09e-118	359.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XE7N@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_28814_1	526227.Mesil_0601	4.17e-112	337.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_7690_1	1121403.AUCV01000010_gene1377	3.1e-41	154.0	COG2885@1|root,COG3221@1|root,COG2885@2|Bacteria,COG3221@2|Bacteria,1R687@1224|Proteobacteria,42ZCB@68525|delta/epsilon subdivisions,2WTSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,OmpA
k59_115827_1	1168034.FH5T_18905	5.23e-102	303.0	COG5523@1|root,COG5523@2|Bacteria,4NM5R@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
k59_231622_1	1165841.SULAR_09094	8.28e-44	153.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_247266_1	1123360.thalar_00005	2.37e-39	151.0	COG3210@1|root,COG4932@1|root,COG3210@2|Bacteria,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_185580_1	886379.AEWI01000022_gene188	5.35e-113	334.0	COG3385@1|root,COG3385@2|Bacteria,4PAZ3@976|Bacteroidetes,2G1BX@200643|Bacteroidia,3XKVM@558415|Marinilabiliaceae	976|Bacteroidetes	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_53922_1	143224.JQMD01000002_gene2276	1.17e-33	123.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1HWRY@117743|Flavobacteriia	976|Bacteroidetes	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_53922_2	313596.RB2501_03045	3.68e-59	191.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia	976|Bacteroidetes	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
k59_115833_1	1167006.UWK_02860	6.91e-148	420.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,42Q8Q@68525|delta/epsilon subdivisions,2WMKQ@28221|Deltaproteobacteria,2MIYE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_216350_1	313596.RB2501_12849	2.82e-95	296.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_138981_1	1210884.HG799464_gene10869	3.29e-66	211.0	COG3328@1|root,COG3328@2|Bacteria,2J0T4@203682|Planctomycetes	203682|Planctomycetes	L	COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_208699_1	1121939.L861_15485	4.95e-83	264.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales	135619|Oceanospirillales	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_69552_1	1123296.JQKE01000057_gene1415	9.42e-78	242.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,2KPJF@206351|Neisseriales	206351|Neisseriales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_15047_1	1165841.SULAR_09444	6.08e-147	419.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,42ND2@68525|delta/epsilon subdivisions,2YMQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_2
k59_23023_1	387093.SUN_1340	1.25e-60	197.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42S7F@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	AI-2E family transporter	MA20_41055	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_46235_1	1165841.SULAR_07640	2.57e-89	280.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
k59_61757_1	321332.CYB_0748	4.1e-66	210.0	COG0637@1|root,COG0637@2|Bacteria,1G2T2@1117|Cyanobacteria,1GZ2D@1129|Synechococcus	1117|Cyanobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_208707_1	1236959.BAMT01000011_gene3218	4.66e-126	375.0	COG0286@1|root,COG5502@1|root,COG0286@2|Bacteria,COG5502@2|Bacteria,1MW3A@1224|Proteobacteria,2VK6V@28216|Betaproteobacteria	28216|Betaproteobacteria	V	type I restriction-modification	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_69565_1	247634.GPB2148_990	6.36e-102	313.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_46246_1	999141.GME_04667	4.73e-29	104.0	COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1XKZ6@135619|Oceanospirillales	135619|Oceanospirillales	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k59_115859_1	261292.Nit79A3_1578	7.31e-81	266.0	COG1262@1|root,COG1262@2|Bacteria,1PWQN@1224|Proteobacteria,2W0G0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_84781_1	493475.GARC_2006	9.32e-22	95.9	2C2CS@1|root,2Z7SK@2|Bacteria,1NCSN@1224|Proteobacteria,1RS0D@1236|Gammaproteobacteria,46AGD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3754)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3754
k59_84781_2	395493.BegalDRAFT_1079	1.55e-44	155.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,460PZ@72273|Thiotrichales	72273|Thiotrichales	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_23039_1	768671.ThimaDRAFT_2361	6.1e-87	269.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales	135613|Chromatiales	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_69580_1	765910.MARPU_00430	6.3e-43	149.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1WX1H@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_115865_1	3988.XP_002535387.1	2.15e-16	82.4	COG1502@1|root,2RKKV@2759|Eukaryota,382RH@33090|Viridiplantae,3GS34@35493|Streptophyta	35493|Streptophyta	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	iECED1_1282.ECED1_0754	PLDc_2
k59_115865_2	1321372.AQQB01000035_gene1220	1.11e-05	48.1	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,1WSHX@1307|Streptococcus suis	91061|Bacilli	M	GDP-mannose 4,6 dehydratase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_139005_1	143224.JQMD01000002_gene2868	6.82e-27	107.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HX79@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_139005_2	1121875.KB907547_gene3260	7.17e-72	220.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1I263@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162328_1	504472.Slin_2687	8.77e-66	221.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47KIX@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,fn3
## 8827 queries scanned
## Total time (seconds): 91.54095029830933
## Rate: 96.43 q/s