## Sat Jan  4 06:21:10 2025
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA629394/SRR11734700/SRR11734700_p_cluster_rep_seq.fasta --output PRJNA629394_SRR11734700 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k59_76715_1	387093.SUN_1451	3.9e-20	83.2	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42WPX@68525|delta/epsilon subdivisions,2YQEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG1734 DnaK suppressor protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_76715_2	649639.Bcell_2864	3.42e-22	95.5	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,1ZBQE@1386|Bacillus	91061|Bacilli	E	Belongs to the AlaDH PNT family	ald	GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_199025_1	329726.AM1_3021	1.35e-33	123.0	COG0639@1|root,COG0639@2|Bacteria,1G70Z@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
k59_178316_1	1121447.JONL01000003_gene3211	1e-28	118.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2M93H@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_144429_1	1120966.AUBU01000016_gene3070	1.45e-14	81.6	COG1361@1|root,COG2911@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,4PPBJ@976|Bacteroidetes,47TYA@768503|Cytophagia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_29450_1	1122134.KB893650_gene1281	3.83e-88	269.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1XHK7@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09788	ko00640,map00640	-	R11264	RC03405	ko00000,ko00001,ko01000	-	-	-	PrpF
k59_212361_1	1049564.TevJSym_aa01660	1.92e-41	137.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1J6MP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_15864_1	631362.Thi970DRAFT_04985	4.76e-96	298.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1R97Q@1224|Proteobacteria,1RRDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_110701_1	1356852.N008_15595	2.18e-44	164.0	COG0714@1|root,COG0714@2|Bacteria,4NGEG@976|Bacteroidetes,47NU2@768503|Cytophagia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
k59_69945_2	1279009.ADICEAN_00034	2.44e-10	60.1	2C8PG@1|root,32RMK@2|Bacteria,4P5DF@976|Bacteroidetes,47VYD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144436_1	1278073.MYSTI_08069	4.55e-05	47.4	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_42808_1	880070.Cycma_3198	2.09e-67	216.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
k59_2340_1	717774.Marme_0026	2.81e-43	142.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S9Q7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Addiction module toxin	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k59_2340_2	391615.ABSJ01000027_gene178	5.9e-49	157.0	COG2161@1|root,COG2161@2|Bacteria,1N0JP@1224|Proteobacteria,1SA1E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k59_151329_1	1237149.C900_05289	4.81e-28	119.0	2DBDU@1|root,2Z8P5@2|Bacteria,4NFFA@976|Bacteroidetes,47TRU@768503|Cytophagia	976|Bacteroidetes	S	Lantibiotic dehydratase, C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Lant_dehydr_N
k59_212369_1	483219.LILAB_30890	4.38e-16	82.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YWFH@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07714,ko:K07715	ko02020,ko02024,map02020,map02024	M00500,M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_69953_1	313596.RB2501_08775	1.56e-21	85.1	2E6MW@1|root,3318G@2|Bacteria,4NWFR@976|Bacteroidetes,1I55U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49932_1	616991.JPOO01000001_gene4473	2.7e-76	231.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_49932_2	313603.FB2170_00360	5.89e-31	117.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia,2PG9T@252356|Maribacter	976|Bacteroidetes	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_178332_1	1049564.TevJSym_ad00460	1.21e-57	186.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria	1224|Proteobacteria	P	Na H antiporter, MnhB	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
k59_69956_1	1165841.SULAR_10089	5.16e-125	370.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_164831_1	179408.Osc7112_5729	1.52e-81	272.0	COG0515@1|root,COG2114@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,PAS_3,Pkinase
k59_9009_1	1288826.MSNKSG1_00526	1.19e-89	277.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_117658_1	395493.BegalDRAFT_1718	2.3e-39	137.0	COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,1S7QS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_158234_1	387093.SUN_0659	1.23e-28	107.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2YNVB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_158234_2	1165841.SULAR_04152	2.16e-29	114.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_15885_1	387093.SUN_0170	2.7e-78	248.0	COG1246@1|root,COG2172@1|root,COG1246@2|Bacteria,COG2172@2|Bacteria,1QZN7@1224|Proteobacteria,43CKZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15885_2	387093.SUN_0171	2.04e-07	52.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2YTM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_76752_1	926556.Echvi_3754	4.72e-06	54.3	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG4977@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,COG4977@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_144459_1	1137799.GZ78_02265	2.21e-26	103.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XI5Y@135619|Oceanospirillales	135619|Oceanospirillales	C	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k59_144459_2	205914.HS_1277	9.86e-28	112.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1Y7RE@135625|Pasteurellales	135625|Pasteurellales	C	fumarate reductase, flavoprotein subunit	frdA	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_178343_1	395493.BegalDRAFT_3486	1.99e-49	159.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,4613V@72273|Thiotrichales	72273|Thiotrichales	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_178343_2	1123502.AQXD01000001_gene854	1.87e-18	86.7	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1X2XH@135614|Xanthomonadales	135614|Xanthomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_36045_1	1249997.JHZW01000003_gene3900	7.86e-121	359.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia,2PGP2@252356|Maribacter	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_130986_1	869210.Marky_1642	6.64e-68	220.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_124249_1	1165841.SULAR_06813	3.97e-75	228.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2YNZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_69962_1	2340.JV46_26120	5.17e-21	87.8	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1JBWT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ACT domain	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT,ACT_6
k59_69962_2	2340.JV46_26130	1.89e-95	287.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1SJJV@1236|Gammaproteobacteria,1J77S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	-	-	-	-	-	-	-	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
k59_97274_1	329726.AM1_4531	2.37e-06	59.3	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	aprA	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009405,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0031638,GO:0043170,GO:0044238,GO:0044419,GO:0051604,GO:0051704,GO:0071704,GO:0140096,GO:1901564	3.4.24.40	ko:K01406,ko:K20276	ko01503,ko02024,map01503,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HemolysinCabind,Peptidase_M10,Peptidase_M10_C,Reprolysin_4
k59_144467_1	313628.LNTAR_15142	1.3e-19	93.6	COG1205@1|root,COG1205@2|Bacteria	2|Bacteria	L	dead DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
k59_90555_1	1500893.JQNB01000001_gene2575	1.03e-08	62.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_171765_1	317936.Nos7107_2700	1.83e-13	69.7	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,gag-asp_proteas
k59_15896_1	1165841.SULAR_04437	1.51e-75	229.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065	OstA
k59_15896_2	387093.SUN_1223	7.5e-37	129.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2YP3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_192092_1	1168065.DOK_10682	1.08e-75	242.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1J5D6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-associated, metal-dependent hydrolase	eptA	-	2.7.8.43	ko:K03760,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_144474_1	1403819.BATR01000053_gene1641	3.71e-11	68.9	COG3209@1|root,COG3209@2|Bacteria,46UCN@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VCBS
k59_137739_1	29730.Gorai.001G162000.1	7.3e-97	291.0	COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,3GF4E@35493|Streptophyta	35493|Streptophyta	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis	cob	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_137739_2	102107.XP_008244829.1	2.45e-55	174.0	COG0199@1|root,KOG1741@2759|Eukaryota,37W8N@33090|Viridiplantae,3GKAP@35493|Streptophyta,4JU67@91835|fabids	35493|Streptophyta	J	Ribosomal protein S14p/S29e	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_137739_3	3847.GLYMA0405S00215.1	2.78e-98	291.0	COG0199@1|root,KOG1741@2759|Eukaryota,3896F@33090|Viridiplantae,3GY3H@35493|Streptophyta,4JWAW@91835|fabids	35493|Streptophyta	J	Ribosomal protein S14p/S29e	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S14
k59_22628_1	243090.RB8035	5.02e-89	277.0	COG0569@1|root,COG0569@2|Bacteria,2IXXC@203682|Planctomycetes	203682|Planctomycetes	C	TRK potassium uptake system protein (TrkA-2)	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_131003_1	2340.JV46_17100	2.52e-152	451.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1J4W4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_76781_1	765913.ThidrDRAFT_2035	2.29e-114	336.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria,1WWM7@135613|Chromatiales	135613|Chromatiales	C	reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_63356_1	1283300.ATXB01000002_gene2755	1.58e-60	210.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria,1XG68@135618|Methylococcales	135618|Methylococcales	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_97286_1	870187.Thini_1206	2.34e-72	222.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,460SA@72273|Thiotrichales	72273|Thiotrichales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_178352_1	41431.PCC8801_0584	3.54e-77	242.0	COG1619@1|root,COG1619@2|Bacteria,1G059@1117|Cyanobacteria,3KFPI@43988|Cyanothece	1117|Cyanobacteria	V	Peptidase U61, LD-carboxypeptidase A	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k59_137762_1	744980.TRICHSKD4_5066	3.25e-21	90.5	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2U404@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Auxin efflux carrier family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_137762_2	247634.GPB2148_3624	4.31e-75	247.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
k59_76799_1	316274.Haur_2403	6.06e-55	191.0	COG2304@1|root,COG2304@2|Bacteria,2GA79@200795|Chloroflexi,375RC@32061|Chloroflexia	2|Bacteria	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,FG-GAP_2,FctA,VWA,VWA_2
k59_164862_1	314230.DSM3645_06014	2.22e-10	63.9	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_164862_2	313628.LNTAR_06709	1.44e-20	90.9	COG3119@1|root,COG3119@2|Bacteria	313628.LNTAR_06709|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_69981_1	313628.LNTAR_00635	2.69e-36	132.0	COG1253@1|root,COG1253@2|Bacteria	2|Bacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_49978_1	1187848.AJYQ01000008_gene532	7.53e-91	278.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC2	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_117692_1	768671.ThimaDRAFT_3029	4.92e-54	188.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1X2UG@135613|Chromatiales	135613|Chromatiales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_212395_1	1168034.FH5T_11015	6.18e-63	204.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia	976|Bacteroidetes	J	serine--tRNA ligase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_97871_1	1168034.FH5T_10705	2.2e-63	206.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FPA0@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k59_45664_2	1111732.AZOD01000033_gene740	1.34e-76	236.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1X3QU@135614|Xanthomonadales	135614|Xanthomonadales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
k59_79632_1	331113.SNE_A16000	6.97e-89	288.0	COG0060@1|root,COG0060@2|Bacteria,2JFQJ@204428|Chlamydiae	204428|Chlamydiae	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_214863_1	314285.KT71_18441	7.12e-38	131.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,1SANT@1236|Gammaproteobacteria,1J8PD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_214863_2	314285.KT71_18436	1.95e-34	132.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,1RSIU@1236|Gammaproteobacteria,1JBRF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Prokaryotic cytochrome b561	ydhU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08354	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko02000	5.A.3.5	-	-	Cytochrome_C7,Ni_hydr_CYTB
k59_72805_1	575540.Isop_0891	7.73e-16	78.2	COG1131@1|root,COG1131@2|Bacteria,2IY2I@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_72805_2	715451.ambt_13950	2.91e-11	66.2	COG1668@1|root,COG1668@2|Bacteria,1NK4G@1224|Proteobacteria,1RMMK@1236|Gammaproteobacteria,464BJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	CP	COG1668 ABC-type Na efflux pump, permease component	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_38424_2	1434325.AZQN01000002_gene1282	1.44e-37	137.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_32198_1	1121875.KB907547_gene3408	3.14e-14	69.3	2CWZM@1|root,32T0R@2|Bacteria,4NSUM@976|Bacteroidetes,1I4Q2@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
k59_32198_2	313596.RB2501_04470	1.04e-34	122.0	COG4103@1|root,COG4103@2|Bacteria,4NWM3@976|Bacteroidetes,1I5QJ@117743|Flavobacteriia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5329_2	243365.CV_3801	5.39e-32	115.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,2KQY9@206351|Neisseriales	206351|Neisseriales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_174424_1	1173026.Glo7428_2165	4.34e-12	71.6	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_113000_1	1168034.FH5T_19015	7.05e-72	231.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_167657_1	1484479.DI14_06120	2.18e-09	58.2	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,3WE3D@539002|Bacillales incertae sedis	91061|Bacilli	KT	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_167657_2	858215.Thexy_1115	2.02e-11	67.0	COG2972@1|root,COG5002@1|root,COG2972@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,42ENF@68295|Thermoanaerobacterales	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_120464_1	765912.Thimo_0168	3.03e-36	132.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_140447_1	1165841.SULAR_08879	1.32e-69	224.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2YS4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
k59_59340_1	1454202.PPBDW_140235___1	5.67e-59	205.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XTMU@135623|Vibrionales	135623|Vibrionales	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	GO:0000166,GO:0003674,GO:0003824,GO:0004386,GO:0005488,GO:0005524,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
k59_32205_1	1121405.dsmv_0691	2.93e-123	368.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_79650_1	1444711.CCJF01000003_gene35	5.25e-13	75.1	2DBB8@1|root,2Z867@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3383)	Z012_10460	-	-	-	-	-	-	-	-	-	-	-	DUF3383
k59_214884_1	1032480.MLP_27670	2.75e-54	184.0	COG1181@1|root,COG1181@2|Bacteria,2IAF3@201174|Actinobacteria,4DVZ5@85009|Propionibacteriales	201174|Actinobacteria	M	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_4,CPSase_L_D2
k59_187989_1	1121396.KB892913_gene116	4.57e-38	141.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_127115_1	314275.MADE_000001022515	6.67e-13	70.5	COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ORF located using Glimmer RBSfinder	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A,DNA_pol_A_exo1
k59_181182_1	616991.JPOO01000003_gene2582	3.2e-57	188.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia,23G2I@178469|Arenibacter	976|Bacteroidetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_18739_1	768671.ThimaDRAFT_0054	4.66e-30	113.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1WZFD@135613|Chromatiales	135613|Chromatiales	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_18739_2	1123401.JHYQ01000005_gene292	1.31e-19	85.1	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,4608G@72273|Thiotrichales	72273|Thiotrichales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_167680_1	1165841.SULAR_06918	4.81e-112	328.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2YMK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_161036_1	2340.JV46_22570	3.28e-32	127.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,1RR35@1236|Gammaproteobacteria,1J87X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k59_194954_1	1453501.JELR01000002_gene342	6.15e-23	102.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_140467_1	1165841.SULAR_10019	1.05e-85	275.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_59362_1	1298593.TOL_2969	5.91e-75	246.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1XR9E@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_127129_1	870187.Thini_4176	3.26e-121	366.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,45ZS9@72273|Thiotrichales	72273|Thiotrichales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_201646_1	59538.XP_005980035.1	9.08e-33	122.0	COG2518@1|root,KOG1661@2759|Eukaryota	2759|Eukaryota	O	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity	-	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT,Peptidase_M23
k59_93363_1	398512.JQKC01000020_gene4049	7.08e-47	169.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_86494_1	696281.Desru_2645	7.67e-13	73.9	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,24AIF@186801|Clostridia,261A8@186807|Peptococcaceae	186801|Clostridia	C	PFAM Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
k59_134098_1	1408473.JHXO01000010_gene3561	5.34e-79	251.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
k59_79673_1	1392490.JHZX01000001_gene2747	6.85e-88	286.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes,1I0F2@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_120498_1	1232410.KI421415_gene3011	7.22e-39	147.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43RX7@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_72830_1	2340.JV46_03400	5.21e-57	181.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1J4HC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_72830_2	523791.Kkor_2000	4.25e-10	60.8	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XH93@135619|Oceanospirillales	135619|Oceanospirillales	J	Elongation factor P--(R)-beta-lysine ligase	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k59_18757_1	395493.BegalDRAFT_2330	2.9e-65	220.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_127133_1	1168034.FH5T_10045	6.76e-80	248.0	COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,2FM31@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_59371_2	387093.SUN_0531	1.48e-92	279.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2YNKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_174461_1	1195236.CTER_4324	1.4e-30	122.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_66152_1	317025.Tcr_0147	1.93e-17	80.5	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,1RPIZ@1236|Gammaproteobacteria,460KR@72273|Thiotrichales	72273|Thiotrichales	E	PFAM FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_66152_2	1165841.SULAR_08794	6.03e-35	119.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria	1224|Proteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_66152_3	1165841.SULAR_08789	5.39e-62	196.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2YMUY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_120502_1	870967.VIS19158_20177	2.06e-41	154.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1XV77@135623|Vibrionales	135623|Vibrionales	J	COG0008 Glutamyl- and glutaminyl-tRNA synthetases	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_174462_1	1089553.Tph_c12590	1.01e-45	166.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,42ETI@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_45723_1	479431.Namu_0788	1.74e-17	84.7	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4EV02@85013|Frankiales	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
k59_18761_1	754477.Q7C_858	6.5e-82	256.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,45ZZ3@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_79687_1	631362.Thi970DRAFT_03477	7.13e-89	279.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1WXBH@135613|Chromatiales	135613|Chromatiales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_161062_1	1165841.SULAR_10054	4.94e-125	367.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2YMGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144	COX1
k59_208512_2	1125863.JAFN01000001_gene1259	8.59e-30	112.0	2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_181196_1	387093.SUN_1132	4.21e-28	102.0	2AK4P@1|root,31AUI@2|Bacteria,1Q664@1224|Proteobacteria,42X10@68525|delta/epsilon subdivisions,2YQR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_181196_2	1165841.SULAR_04292	5.1e-36	123.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2YQ7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_11678_1	1168034.FH5T_10385	1.32e-90	294.0	COG1277@1|root,COG1277@2|Bacteria,4NI5T@976|Bacteroidetes,2FNVZ@200643|Bacteroidia	976|Bacteroidetes	E	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_80093_1	1274.HX89_02920	3.5e-17	87.0	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria,1ZX6M@145357|Dermacoccaceae	201174|Actinobacteria	L	ATP-dependent helicase C-terminal	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_46271_1	1026882.MAMP_00066	3.72e-30	112.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,4619W@72273|Thiotrichales	72273|Thiotrichales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k59_148121_1	1283300.ATXB01000001_gene660	1.86e-110	328.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1XDX9@135618|Methylococcales	135618|Methylococcales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_202169_1	262768.PAM_250	4.7e-13	68.2	2B9ZZ@1|root,323DM@2|Bacteria,3WUUY@544448|Tenericutes	2|Bacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_202169_2	1232449.BAHV02000026_gene945	1.94e-07	50.8	2DQE0@1|root,33689@2|Bacteria,1VH8J@1239|Firmicutes,24WJ6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_134537_1	566466.NOR53_372	2.61e-63	209.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1J836@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	ybaL	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_134537_2	177437.HRM2_46300	1.21e-19	84.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2WMW2@28221|Deltaproteobacteria,2MJQE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_148124_1	1045855.DSC_09310	2.45e-45	158.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1X47D@135614|Xanthomonadales	135614|Xanthomonadales	E	Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine	metX	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_20496_2	395493.BegalDRAFT_0025	1.18e-34	128.0	COG0607@1|root,COG0607@2|Bacteria,1R71B@1224|Proteobacteria,1S2D9@1236|Gammaproteobacteria,4637I@72273|Thiotrichales	72273|Thiotrichales	KP	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_20497_1	1144319.PMI16_02458	6.23e-77	243.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VIT6@28216|Betaproteobacteria,472YH@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_162821_2	102129.Lepto7375DRAFT_5371	1.63e-24	100.0	COG0325@1|root,COG0325@2|Bacteria,1G0GQ@1117|Cyanobacteria,1H7WV@1150|Oscillatoriales	1117|Cyanobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_13713_1	3880.AES58577	1.43e-77	256.0	COG0056@1|root,COG0356@1|root,COG1622@1|root,KOG1353@2759|Eukaryota,KOG4665@2759|Eukaryota,KOG4767@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta,4JSJY@91835|fabids	35493|Streptophyta	C	ATP synthase	atp1	-	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,COX2_TM
k59_203480_1	1165841.SULAR_01988	7.23e-106	313.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42QNP@68525|delta/epsilon subdivisions,2YR5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_40803_1	1168034.FH5T_08360	5.07e-75	232.0	2CC7H@1|root,32RJ0@2|Bacteria,4NIDZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149231_1	765912.Thimo_3207	4.68e-44	159.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,1RSJ4@1236|Gammaproteobacteria,1WWJR@135613|Chromatiales	135613|Chromatiales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
k59_142468_1	272558.10175675	8.04e-13	73.6	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_108590_1	313596.RB2501_15524	1.25e-65	221.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
k59_169570_1	1165841.SULAR_07550	1.19e-128	378.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_156066_1	1165841.SULAR_04307	4.17e-25	100.0	COG0770@1|root,COG0770@2|Bacteria,1Q1GK@1224|Proteobacteria,42TKM@68525|delta/epsilon subdivisions,2YSXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_156066_2	1165841.SULAR_04302	6.46e-67	220.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_108596_1	1165841.SULAR_09349	3.32e-133	382.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_108596_2	1165841.SULAR_09354	8.6e-28	108.0	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_108597_1	1161901.I1TLG7_9CAUD	2.52e-07	57.4	4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses  no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae	10699|Siphoviridae	S	DNA polymerase family A	-	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	-
k59_34065_1	338966.Ppro_2354	8.48e-17	79.3	COG0778@1|root,COG0778@2|Bacteria,1PE5U@1224|Proteobacteria,42VB3@68525|delta/epsilon subdivisions,2WS8C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Nitroreductase
k59_34065_2	1121875.KB907551_gene1175	2.4e-73	233.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HZHR@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_149252_1	7668.SPU_017605-tr	1.49e-98	303.0	COG0056@1|root,KOG1353@2759|Eukaryota,38ERH@33154|Opisthokonta,3BCEE@33208|Metazoa,3CU79@33213|Bilateria	33208|Metazoa	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	ATP5A1	GO:0000275,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0006091,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0010876,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0019915,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0022900,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033036,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0050790,GO:0051179,GO:0051234,GO:0051235,GO:0051338,GO:0055085,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1902769	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_156070_1	1121935.AQXX01000110_gene5465	7.44e-91	286.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1XHNX@135619|Oceanospirillales	135619|Oceanospirillales	M	penicillin-binding protein	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_203496_1	655815.ZPR_2447	1.55e-134	413.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_196725_1	1165841.SULAR_09399	0.0	938.0	COG1262@1|root,COG1352@1|root,COG1262@2|Bacteria,COG1352@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_67985_1	1165841.SULAR_04432	6.27e-85	254.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2YP3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_67985_2	1165841.SULAR_04427	2.35e-69	212.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2YPNW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetyltransferase	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_189941_1	105420.BBPO01000046_gene990	2.37e-08	60.8	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
k59_108600_1	2340.JV46_05270	1.77e-24	97.4	COG2863@1|root,COG2863@2|Bacteria,1R8K9@1224|Proteobacteria,1S1Q4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Cytochrome C	fccA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_108600_2	1121447.JONL01000003_gene3077	1.88e-47	165.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_135700_1	234267.Acid_5112	1.92e-81	253.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_135700_2	1150399.AQYK01000002_gene2988	5.61e-13	65.9	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4FNXV@85023|Microbacteriaceae	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_122157_1	1179773.BN6_12200	1.39e-30	130.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4DX3H@85010|Pseudonocardiales	201174|Actinobacteria	L	SNF2 family N-terminal domain	helZ	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
k59_101876_1	234267.Acid_3262	2.8e-07	58.5	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_3262|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
k59_176387_1	203122.Sde_1721	5.62e-62	203.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,4649H@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_135703_1	1254432.SCE1572_25005	6.88e-75	252.0	COG0604@1|root,COG1028@1|root,COG3321@1|root,COG0604@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2X5FS@28221|Deltaproteobacteria,2Z35D@29|Myxococcales	28221|Deltaproteobacteria	CQ	Enoylreductase	-	-	-	ko:K12436,ko:K16396,ko:K16397	ko01052,map01052	-	-	-	ko00000,ko00001,ko01004	-	-	-	ADH_N,ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_176391_2	105559.Nwat_0324	0.000208	47.4	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	3D,PG_binding_1,VanY
k59_196745_1	1211814.CAPG01000034_gene1617	1.93e-09	55.8	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,1ZH44@1386|Bacillus	91061|Bacilli	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
k59_13754_1	1168034.FH5T_14120	5.89e-87	260.0	28H8Z@1|root,30SVU@2|Bacteria,4NY56@976|Bacteroidetes	976|Bacteroidetes	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
k59_13754_2	468059.AUHA01000002_gene1124	2.54e-13	70.1	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1INSY@117747|Sphingobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_156082_2	349123.Lreu23DRAFT_3398	8.14e-12	63.2	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_210295_1	387093.SUN_1196	2.42e-102	311.0	COG0665@1|root,COG0665@2|Bacteria,1QV9J@1224|Proteobacteria,42PP0@68525|delta/epsilon subdivisions,2YNBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_20538_1	3649.evm.model.supercontig_89.21	9.48e-38	130.0	2E3CF@1|root,2R1SP@2759|Eukaryota,383GK@33090|Viridiplantae,3GX0Z@35493|Streptophyta,3I1GY@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34091_1	1340493.JNIF01000003_gene3078	1.6e-05	52.4	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
k59_54369_2	1408419.JHYG01000001_gene1886	4.35e-60	192.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,2JPYJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
k59_74719_1	383407.XOC_2197	5.61e-47	173.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1X4R3@135614|Xanthomonadales	135614|Xanthomonadales	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k59_169621_2	1123267.JONN01000001_gene1425	7.09e-10	63.2	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria,2K1K2@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_27323_1	439235.Dalk_2635	2.28e-62	210.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,2MJBM@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_135725_1	1168034.FH5T_19585	3.06e-61	202.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,2G336@200643|Bacteroidia	976|Bacteroidetes	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_47604_1	1046724.KB889870_gene2353	8.36e-07	49.7	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,465M8@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_95081_1	1117647.M5M_07040	7.87e-89	281.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1J7YQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2015 Alkyl sulfatase and related hydrolases	BDS1	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_13766_1	1165841.SULAR_00350	1.96e-87	266.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2YMEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_13766_2	1123514.KB905903_gene365	3.87e-20	90.5	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,1RNZA@1236|Gammaproteobacteria,462PN@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27330_1	176299.Atu3673	3.41e-05	51.6	COG0236@1|root,COG0318@1|root,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,4BI55@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_101898_1	203124.Tery_1703	5.5e-66	218.0	COG2192@1|root,COG2192@2|Bacteria,1G1FV@1117|Cyanobacteria,1H9E9@1150|Oscillatoriales	1117|Cyanobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_88334_1	583345.Mmol_0227	4.02e-60	205.0	COG0323@1|root,COG0323@2|Bacteria,1R57G@1224|Proteobacteria,2VP7W@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA mismatch repair	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
k59_13771_1	1168034.FH5T_17330	3.5e-77	243.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,2FP4W@200643|Bacteroidia	976|Bacteroidetes	D	SpoIID LytB domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
k59_48087_1	1165841.SULAR_00420	7.33e-117	340.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_149764_1	862751.SACTE_6230	1.37e-41	140.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria	201174|Actinobacteria	CO	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
k59_149764_2	1236542.BALM01000039_gene3998	2.5e-15	73.9	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,1S6MA@1236|Gammaproteobacteria,2QBXW@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k59_88811_1	1121875.KB907547_gene3261	1.78e-212	619.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1HXWA@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_176855_1	2340.JV46_27920	1.67e-109	319.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_197263_1	1250232.JQNJ01000001_gene3716	1.99e-15	75.1	COG0364@1|root,COG0364@2|Bacteria,4NE59@976|Bacteroidetes,1HWVJ@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_197263_2	694427.Palpr_2271	1.96e-32	121.0	COG0363@1|root,COG0363@2|Bacteria,4NGB9@976|Bacteroidetes,2FNZF@200643|Bacteroidia,22XT3@171551|Porphyromonadaceae	976|Bacteroidetes	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_88815_1	1121035.AUCH01000007_gene509	1.32e-95	302.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,2KUV3@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdopterin,Molydop_binding
k59_7365_2	67373.JOBF01000027_gene1610	5.32e-11	65.9	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria	201174|Actinobacteria	O	Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_173945_1	234267.Acid_2264	1.9e-72	234.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
k59_18281_2	96561.Dole_2473	1.51e-15	80.9	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,43AF4@68525|delta/epsilon subdivisions,2X5UV@28221|Deltaproteobacteria,2MPG4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_133615_1	323261.Noc_1173	2.97e-05	47.8	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
k59_106549_2	1165841.SULAR_09934	2.63e-183	517.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_31796_1	1150469.RSPPHO_00007	6.32e-42	152.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,2TRD4@28211|Alphaproteobacteria,2JPQD@204441|Rhodospirillales	204441|Rhodospirillales	J	lysyl-tRNA synthetase	poxA	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k59_147122_1	1165841.SULAR_08909	2.7e-137	418.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_4883_1	1165841.SULAR_01270	1.7e-118	370.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_65634_1	1165841.SULAR_01708	1.91e-234	646.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_72341_1	411154.GFO_0807	1.39e-76	253.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1HYNJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_167115_1	485917.Phep_3798	2.25e-07	63.5	COG5492@1|root,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,1IT6W@117747|Sphingobacteriia	976|Bacteroidetes	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_120031_2	395493.BegalDRAFT_3116	3.01e-61	197.0	COG1682@1|root,COG1682@2|Bacteria,1QR2A@1224|Proteobacteria,1SMDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
k59_31800_1	948071.S4S2D9_9CAUD	3.33e-79	256.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae	10744|Podoviridae	S	ribonucleoside-triphosphate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214444_1	880073.Calab_3581	2.17e-71	241.0	COG0841@1|root,COG0841@2|Bacteria,2NQKZ@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_31801_1	697282.Mettu_1699	5.02e-13	70.1	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XFYJ@135618|Methylococcales	135618|Methylococcales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_4,PAS_9
k59_45143_1	1165841.SULAR_08382	1.93e-21	92.4	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2YMJN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
k59_208071_1	1009370.ALO_19402	0.000168	43.5	COG0583@1|root,COG0583@2|Bacteria,1UXNZ@1239|Firmicutes,4H7ZQ@909932|Negativicutes	909932|Negativicutes	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_52064_1	2340.JV46_21910	7.05e-90	289.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T216@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
k59_18298_1	1168034.FH5T_06745	4.52e-22	94.4	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,2G3BA@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_38063_1	1408473.JHXO01000001_gene2384	1.7e-61	204.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,2FMRY@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
k59_72358_1	1131269.AQVV01000025_gene2336	7.71e-31	119.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
k59_11256_1	1255043.TVNIR_0174	9.87e-34	135.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,1X2AB@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,Response_reg
k59_201135_1	1165841.SULAR_04252	9.11e-109	333.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2YNBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_4904_1	522306.CAP2UW1_1884	4.73e-09	61.6	COG0348@1|root,COG0633@1|root,COG1251@1|root,COG0348@2|Bacteria,COG0633@2|Bacteria,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria,1KQXB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Pyr_redox_2
k59_4904_2	1242864.D187_007682	4.47e-24	97.4	COG1670@1|root,COG1670@2|Bacteria,1N9F9@1224|Proteobacteria	1224|Proteobacteria	J	Protein of unknown function (DUF3565)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3565
k59_45161_1	1313421.JHBV01000030_gene2141	2.17e-39	154.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NIFD@976|Bacteroidetes	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
k59_18308_1	292415.Tbd_0575	5.78e-97	284.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2VS0Z@28216|Betaproteobacteria,1KSU4@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_65661_1	765913.ThidrDRAFT_3184	4.72e-57	201.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
k59_18309_1	240016.ABIZ01000001_gene99	4.83e-58	197.0	COG2939@1|root,COG2939@2|Bacteria,46UB7@74201|Verrucomicrobia,2IVCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_18311_1	1049564.TevJSym_be00280	1.39e-72	234.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1J55B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_2885	Glu_cys_ligase
k59_18314_1	1165841.SULAR_01538	1.06e-57	189.0	COG0845@1|root,COG0845@2|Bacteria,1PZ6R@1224|Proteobacteria	1224|Proteobacteria	M	COG0845 membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_120053_1	1173026.Glo7428_1262	1.95e-84	269.0	COG2304@1|root,COG2304@2|Bacteria,1G1BE@1117|Cyanobacteria	1117|Cyanobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_214468_2	1121022.ABENE_18050	3.35e-23	102.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VF1X@28211|Alphaproteobacteria,2KK2H@204458|Caulobacterales	204458|Caulobacterales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_180736_1	187272.Mlg_1642	1.37e-27	115.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,1RMH4@1236|Gammaproteobacteria,1X0XW@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_65663_1	1392490.JHZX01000001_gene2886	1.65e-86	261.0	COG2267@1|root,COG2267@2|Bacteria,4NFDA@976|Bacteroidetes,1HYMF@117743|Flavobacteriia	976|Bacteroidetes	I	Arylesterase	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_65663_2	1239415.CM001837_gene1777	6.24e-11	61.6	COG2808@1|root,COG2808@2|Bacteria,4NINW@976|Bacteroidetes,1HZF0@117743|Flavobacteriia,37E1M@326319|Dokdonia	976|Bacteroidetes	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
k59_52098_1	70601.3257265	2.3e-17	79.3	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_52098_2	1122179.KB890480_gene3110	2.43e-23	98.2	29X2D@1|root,30IQV@2|Bacteria,4NPC2@976|Bacteroidetes	976|Bacteroidetes	S	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
k59_65664_1	313596.RB2501_14844	6.8e-38	135.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1HWKK@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_194534_1	903818.KI912268_gene3191	2.52e-12	65.9	COG4911@1|root,COG4911@2|Bacteria,3Y4VB@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
k59_11269_1	13333.ERN02618	4.63e-280	815.0	COG0052@1|root,COG0356@1|root,KOG0832@2759|Eukaryota,KOG4665@2759|Eukaryota,38964@33090|Viridiplantae,3GY32@35493|Streptophyta	35493|Streptophyta	J	RNA polymerase Rpb1, domain 5	rpoC2	-	2.7.7.6	ko:K02108,ko:K03046	ko00190,ko00195,ko00230,ko00240,ko01100,ko03020,map00190,map00195,map00230,map00240,map01100,map03020	M00157,M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko00194,ko01000,ko03021,ko03110,ko03400	3.A.2.1	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,Ribosomal_S2
k59_11269_2	59689.scaffold_201045.1	0.0	976.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,3I0YM@3699|Brassicales	35493|Streptophyta	K	rna polymerase	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_140108_1	1116472.MGMO_173c00050	1.61e-26	108.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XE56@135618|Methylococcales	135618|Methylococcales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	-
k59_208103_1	29730.Gorai.007G237900.1	9.26e-06	43.9	2EQ7X@1|root,2ST9U@2759|Eukaryota,3819J@33090|Viridiplantae,3GQNF@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194540_1	1168034.FH5T_17600	6.65e-43	152.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,2FMEM@200643|Bacteroidia	976|Bacteroidetes	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
k59_174476_1	2340.JV46_27820	6.85e-139	404.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1J4J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_66171_1	1165841.SULAR_04602	3.52e-71	221.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_66171_2	1165841.SULAR_04607	2.02e-09	57.8	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,42MX3@68525|delta/epsilon subdivisions,2YR64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2951 Membrane-bound lytic murein transglycosylase B	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_32240_1	243090.RB5028	9.03e-18	87.8	COG0470@1|root,COG0515@1|root,COG1262@1|root,COG0470@2|Bacteria,COG0515@2|Bacteria,COG1262@2|Bacteria,2IY3E@203682|Planctomycetes	203682|Planctomycetes	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
k59_167703_1	313628.LNTAR_11671	0.000199	47.8	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase,YHYH
k59_140492_1	1249627.D779_0899	6.72e-25	100.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1WX0V@135613|Chromatiales	135613|Chromatiales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_140492_2	1122212.AULO01000012_gene1018	9.38e-49	155.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1XKGB@135619|Oceanospirillales	135619|Oceanospirillales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_38493_1	118161.KB235922_gene2608	8.61e-91	279.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1G21B@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_134120_1	765910.MARPU_11355	2.38e-65	214.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1WX7X@135613|Chromatiales	135613|Chromatiales	J	SAM-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_140499_1	439235.Dalk_0746	2.53e-45	156.0	2DBB3@1|root,2Z85F@2|Bacteria,1N6NI@1224|Proteobacteria,4302P@68525|delta/epsilon subdivisions,2WVHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
k59_38497_1	1168034.FH5T_05195	9.18e-94	286.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,2FMUF@200643|Bacteroidia	976|Bacteroidetes	CP	ABC transporter permease	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_174486_2	1121405.dsmv_2744	1.79e-13	75.5	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,42M7Q@68525|delta/epsilon subdivisions,2WJ9Z@28221|Deltaproteobacteria,2MIK8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_107077_1	688269.Theth_0251	5.18e-11	64.3	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_107077_2	1089550.ATTH01000001_gene1773	7.54e-10	58.9	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,1FJX2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Aminotransferase class-V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_59416_1	1268239.PALB_20230	1.07e-18	84.3	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,2Q0K2@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_210135_2	1165841.SULAR_06993	5.58e-08	52.8	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_142367_1	471854.Dfer_5316	4.39e-41	148.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
k59_122039_1	313606.M23134_02529	3.87e-50	181.0	COG1538@1|root,COG2351@1|root,COG3409@1|root,COG1538@2|Bacteria,COG2351@2|Bacteria,COG3409@2|Bacteria,4NJ4W@976|Bacteroidetes,47K3F@768503|Cytophagia	976|Bacteroidetes	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemopexin,VRP1
k59_61020_1	870187.Thini_0347	1.45e-40	137.0	COG3411@1|root,COG3411@2|Bacteria,1N0XK@1224|Proteobacteria,1S9F8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40706_1	983548.Krodi_1613	3.29e-66	210.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia,37DZ8@326319|Dokdonia	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_128809_1	203124.Tery_1361	2.94e-55	195.0	COG0500@1|root,COG0500@2|Bacteria,1G1YB@1117|Cyanobacteria,1HA07@1150|Oscillatoriales	1117|Cyanobacteria	Q	Cyclopropane fatty acid synthase and related methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_61023_1	439235.Dalk_4847	4.26e-40	145.0	COG3385@1|root,COG3385@2|Bacteria,1RCTP@1224|Proteobacteria,431NI@68525|delta/epsilon subdivisions,2WWWQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_122046_1	867900.Celly_2353	2.08e-32	129.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,1FA5X@104264|Cellulophaga	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_40718_1	1121405.dsmv_2856	1.24e-48	171.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_196598_1	1198452.Jab_2c00030	2.53e-78	264.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,473K1@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Linear gramicidin synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_13592_1	1165841.SULAR_05968	3.45e-99	297.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,43BHX@68525|delta/epsilon subdivisions,2YMEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_54264_1	313596.RB2501_07955	1.8e-54	180.0	COG2382@1|root,COG2382@2|Bacteria,4PKIX@976|Bacteroidetes,1IJAG@117743|Flavobacteriia	976|Bacteroidetes	P	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
k59_54264_2	1250232.JQNJ01000001_gene1006	4.89e-22	95.1	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1HY3T@117743|Flavobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_6834_1	1196031.ALEG01000003_gene3224	1.72e-08	61.6	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus	91061|Bacilli	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	-	-	-	ko:K15654,ko:K15655,ko:K15662,ko:K15663	ko01054,ko02024,map01054,map02024	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_108491_1	314285.KT71_10582	2.83e-84	276.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4UY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_135586_1	1150621.SMUL_2005	6.36e-51	166.0	2AWDR@1|root,31N9R@2|Bacteria,1QK0X@1224|Proteobacteria,42U4P@68525|delta/epsilon subdivisions,2YPX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135586_5	1173020.Cha6605_0349	8.21e-12	65.5	COG2988@1|root,COG2988@2|Bacteria,1G2BY@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the AspA AstE family. Aspartoacylase subfamily	aspA	-	3.5.1.15	ko:K01437	ko00250,ko00340,ko01100,map00250,map00340,map01100	-	R00488,R00526	RC00064,RC00165,RC00300,RC00323	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k59_54270_1	387093.SUN_1437	1.14e-35	134.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,43B1H@68525|delta/epsilon subdivisions,2YT54@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_54270_2	1165841.SULAR_01440	4.21e-43	147.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2YMDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_81375_1	1499967.BAYZ01000182_gene4433	8.92e-58	189.0	297CM@1|root,2ZUK5@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
k59_33948_1	1122599.AUGR01000020_gene1525	8.32e-05	48.5	2DC6I@1|root,2ZD2H@2|Bacteria,1QB0V@1224|Proteobacteria,1T6I0@1236|Gammaproteobacteria,1XQQR@135619|Oceanospirillales	135619|Oceanospirillales	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_33948_2	1121918.ARWE01000001_gene951	7e-30	113.0	COG4967@1|root,COG4967@2|Bacteria,1RKKA@1224|Proteobacteria,42Y2V@68525|delta/epsilon subdivisions,2WTFM@28221|Deltaproteobacteria,43V82@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	-	-	-	ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
k59_20388_2	1049564.TevJSym_bd00190	1.22e-99	297.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1JBV7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulatory protein, C terminal	ompR	GO:0000156,GO:0000160,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0035556,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_20388_3	1163617.SCD_n00406	2.66e-08	55.8	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_142382_1	395493.BegalDRAFT_0437	2.54e-63	213.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,GAF,GAF_2,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,Response_reg
k59_162716_1	555778.Hneap_1244	1.43e-29	115.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_162716_2	216142.LT40_03730	6.89e-28	110.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_88167_1	1165841.SULAR_01360	3.43e-90	291.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_94941_1	2340.JV46_25830	3.84e-45	146.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1J6PJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_94941_2	768671.ThimaDRAFT_2830	2.31e-27	99.8	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1WZA6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_135594_1	1168034.FH5T_09440	6.83e-74	223.0	COG0346@1|root,COG0346@2|Bacteria,4NQQA@976|Bacteroidetes	976|Bacteroidetes	E	glyoxalase	gloA	-	4.4.1.5	ko:K01759,ko:K03827	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Glyoxalase,Glyoxalase_4
k59_81382_1	1165841.SULAR_09779	1.04e-57	179.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2YPES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the thioredoxin family	trx2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_81382_2	1165841.SULAR_09774	3.49e-48	161.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2YN1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_64_1	1165841.SULAR_09704	1.96e-54	179.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_64_2	1165841.SULAR_09699	4.02e-123	359.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_122057_1	1150600.ADIARSV_3398	6.47e-20	93.6	28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,1IS7W@117747|Sphingobacteriia	976|Bacteroidetes	S	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
k59_74603_1	870187.Thini_3578	5.28e-85	253.0	COG3012@1|root,COG3012@2|Bacteria,1N4HZ@1224|Proteobacteria,1SFB1@1236|Gammaproteobacteria,462H1@72273|Thiotrichales	72273|Thiotrichales	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94946_1	1295642.H839_18145	1.2e-27	117.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1WF6K@129337|Geobacillus	91061|Bacilli	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_149162_1	886379.AEWI01000005_gene963	7.5e-108	348.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,2FNH9@200643|Bacteroidia,3XJ8U@558415|Marinilabiliaceae	976|Bacteroidetes	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_155960_1	1168034.FH5T_14070	7.16e-37	135.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,2FMXV@200643|Bacteroidia	976|Bacteroidetes	J	S1 RNA binding domain protein	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_47515_1	525898.Sdel_1999	3.06e-243	671.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42QTE@68525|delta/epsilon subdivisions,2YR90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_47515_2	525898.Sdel_1998	5.8e-167	469.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42QX7@68525|delta/epsilon subdivisions,2YRDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_210186_1	765910.MARPU_10625	3.33e-72	241.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_183069_2	553385.JEMF01000027_gene1968	1.39e-24	104.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,1XIBM@135619|Oceanospirillales	135619|Oceanospirillales	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
k59_210188_2	1267535.KB906767_gene2514	1.36e-08	53.1	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_54280_2	313606.M23134_04461	5.27e-28	108.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,47JB0@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_88556_1	1123228.AUIH01000131_gene2866	5.25e-44	160.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1XS1N@135619|Oceanospirillales	135619|Oceanospirillales	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_47838_2	1561998.Csp11.Scaffold629.g13259.t1	5.26e-36	134.0	COG2801@1|root,KOG0017@2759|Eukaryota,39ZX7@33154|Opisthokonta,3BQ45@33208|Metazoa,3D40D@33213|Bilateria,40R4D@6231|Nematoda,1M86G@119089|Chromadorea,40WSN@6236|Rhabditida	33208|Metazoa	L	Chromatin organization modifier domain	-	-	-	-	-	-	-	-	-	-	-	-	Chromo,rve
k59_102148_1	1196028.ALEF01000017_gene2486	2.06e-25	105.0	COG0591@1|root,COG0591@2|Bacteria,1UZ0Z@1239|Firmicutes,4HCWG@91061|Bacilli,4C4I6@84406|Virgibacillus	91061|Bacilli	E	Sodium:solute symporter family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_102148_2	1168034.FH5T_19560	5.18e-60	193.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,2FS6Q@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_20825_1	425104.Ssed_3722	4.16e-94	282.0	COG1136@1|root,COG1136@2|Bacteria,1NHCD@1224|Proteobacteria,1RNIX@1236|Gammaproteobacteria,2QA0D@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC transporter related	ycfV	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_20825_2	493475.GARC_3472	2.34e-16	79.0	COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,465M6@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_34326_1	440512.C211_15020	3.72e-40	153.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	transport system, permease component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_61461_1	99598.Cal7507_0251	1.96e-15	82.4	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG3437@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1GHDJ@1117|Cyanobacteria,1HJNU@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_122420_1	1168034.FH5T_07085	2.9e-38	132.0	28UTG@1|root,2ZGXN@2|Bacteria,4P80G@976|Bacteroidetes,2FZFM@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_122420_2	397291.C804_01764	2.08e-12	68.6	COG0366@1|root,COG1196@1|root,COG1523@1|root,COG3209@1|root,COG0366@2|Bacteria,COG1196@2|Bacteria,COG1523@2|Bacteria,COG3209@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,27K0D@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
k59_163101_1	1450525.JATV01000001_gene2585	2.17e-59	196.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,1I0YN@117743|Flavobacteriia,2NUF6@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
k59_27588_1	713587.THITH_10645	1.03e-91	278.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RVJU@1236|Gammaproteobacteria,1WXJS@135613|Chromatiales	135613|Chromatiales	I	Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_122428_1	1121028.ARQE01000016_gene2619	8.53e-80	248.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2PK0U@255475|Aurantimonadaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_108855_1	1249627.D779_4054	2.59e-57	193.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alkaline phosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_108855_2	1120956.JHZK01000042_gene3049	2.02e-50	168.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,2TV8A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Protein of unknown function (DUF1254)	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	DUF1214,DUF1254
k59_163106_1	391615.ABSJ01000017_gene1674	3.3e-39	145.0	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_8
k59_176649_1	545276.KB898732_gene2472	2.69e-46	157.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1WXG2@135613|Chromatiales	135613|Chromatiales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_183400_1	565045.NOR51B_584	8.2e-95	287.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,1J66V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_169806_1	537972.ABQU01000097_gene1131	2.47e-27	101.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,42S33@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129140_1	713587.THITH_09660	2.23e-68	233.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WX1Z@135613|Chromatiales	135613|Chromatiales	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_163116_1	1163617.SCD_n02290	6.62e-71	243.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
k59_197050_1	177437.HRM2_36010	1.72e-70	217.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MIGC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_197050_2	1232437.KL662001_gene4555	2.38e-17	80.1	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2MI89@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_203770_1	2340.JV46_12300	9.42e-96	297.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1J4W7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
k59_210583_1	2340.JV46_12710	7.56e-82	268.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1J4Y8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_210583_2	2340.JV46_12700	1.73e-31	122.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1J4PD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_88578_1	631362.Thi970DRAFT_01080	1.69e-61	198.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1WWPW@135613|Chromatiales	135613|Chromatiales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_88578_2	754476.Q7A_24	7e-18	82.8	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,463VV@72273|Thiotrichales	72273|Thiotrichales	T	SH3 domain	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k59_78007_1	290397.Adeh_1659	5.85e-90	279.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
k59_3622_1	1165841.SULAR_04868	2.39e-124	369.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_30725_1	1202532.FF52_14614	1.61e-32	125.0	COG0436@1|root,COG0436@2|Bacteria,4PN5Q@976|Bacteroidetes	976|Bacteroidetes	E	Pfam:SusD	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
k59_30725_2	1202532.FF52_14609	8.01e-44	159.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia,2P0MC@237|Flavobacterium	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_84978_1	367737.Abu_0019	3.28e-117	346.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_98597_1	1128421.JAGA01000002_gene861	1.31e-51	173.0	COG2897@1|root,COG2897@2|Bacteria,2NQJ4@2323|unclassified Bacteria	2|Bacteria	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_78009_1	998674.ATTE01000001_gene2238	2.16e-37	134.0	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S9ZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
k59_78009_2	595460.RRSWK_02436	4.09e-08	51.6	COG3324@1|root,COG3324@2|Bacteria,2J3H6@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_152642_1	314265.R2601_05638	6.55e-38	133.0	2E3TX@1|root,32YRB@2|Bacteria,1RAN2@1224|Proteobacteria,2TXXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119034_2	313596.RB2501_06495	1.52e-33	125.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_179412_1	1049564.TevJSym_ac00130	3.46e-171	497.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide	nosZ	GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	COX2,Cupredoxin_1
k59_132368_1	387093.SUN_0366	2.58e-103	320.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2YNPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_119037_1	1165841.SULAR_01345	2.59e-133	404.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_98603_1	95619.PM1_0230905	1.74e-27	115.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	pvdI	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD,Thioesterase
k59_213587_1	1165841.SULAR_03317	1.26e-118	363.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_105258_1	765913.ThidrDRAFT_2620	1.41e-39	147.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,1T2FP@1236|Gammaproteobacteria,1WWXW@135613|Chromatiales	135613|Chromatiales	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2
k59_213589_1	1168034.FH5T_10930	2.08e-97	293.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_179422_1	1449069.JMLO01000030_gene5004	1.22e-13	76.3	COG2304@1|root,COG2304@2|Bacteria,2GIW6@201174|Actinobacteria,4FVB2@85025|Nocardiaceae	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
k59_193302_1	395495.Lcho_4196	1.47e-12	66.6	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,1KIWS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_193302_2	349521.HCH_01901	2.07e-20	89.4	COG0235@1|root,COG0235@2|Bacteria,1N2XS@1224|Proteobacteria,1S573@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PFAM Class II aldolase adducin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
k59_138941_1	1042377.AFPJ01000051_gene87	9.31e-208	588.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,46DHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_37115_2	944547.ABLL_1470	1.85e-51	169.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,42ZWV@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Acyl carrier protein phosphodiesterase	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	ACP_PD
k59_159374_1	1165841.SULAR_00280	1.15e-39	143.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_10258_1	313596.RB2501_03735	2.09e-154	441.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k59_132375_1	930169.B5T_02559	1.3e-35	129.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_64474_1	1165841.SULAR_06753	2.74e-44	152.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2YMPP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin biosynthesis protein	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_64474_2	1165841.SULAR_06748	1.33e-76	233.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2YN11@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_125500_1	882378.RBRH_01359	1.21e-35	124.0	2D16E@1|root,32TA0@2|Bacteria,1MZ7W@1224|Proteobacteria,2VU9S@28216|Betaproteobacteria,1K9M8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Motility quorum-sensing regulator, toxin of MqsA	-	-	-	ko:K13651	-	-	-	-	ko00000,ko02048	-	-	-	MqsR_toxin
k59_125500_2	637390.AFOH01000056_gene1573	1.19e-74	225.0	COG1396@1|root,COG1396@2|Bacteria,1QVJF@1224|Proteobacteria,1T2EB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K13655	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	MqsA_antitoxin
k59_57686_2	1122165.AUHS01000013_gene52	1.02e-06	54.7	COG2267@1|root,COG2267@2|Bacteria,1MYEX@1224|Proteobacteria,1RUUK@1236|Gammaproteobacteria,1JE8Q@118969|Legionellales	118969|Legionellales	I	Serine aminopeptidase, S33	mhpC_2	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_43921_1	313596.RB2501_14429	5.74e-113	337.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1HYM2@117743|Flavobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_50935_1	592029.DDD_0537	6.93e-14	67.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1I18F@117743|Flavobacteriia,3HKAE@363408|Nonlabens	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_50935_2	555500.I215_12178	7.87e-58	179.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_17044_1	580332.Slit_0445	1.78e-56	199.0	COG1643@1|root,COG2852@1|root,COG1643@2|Bacteria,COG2852@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_98610_1	395493.BegalDRAFT_0077	8.84e-33	133.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,460A3@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_166047_1	550540.Fbal_3383	1.98e-86	268.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,1RQD1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5669	Cytochrom_C552
k59_179440_1	272123.Anacy_0404	2.59e-05	50.4	COG0823@1|root,COG0823@2|Bacteria,1G5PS@1117|Cyanobacteria,1HMUU@1161|Nostocales	1117|Cyanobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_125508_1	1165841.SULAR_07143	1.67e-119	345.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2YMWV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_132799_1	391587.KAOT1_13007	8.5e-23	96.3	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
k59_132799_2	616991.JPOO01000003_gene1540	2.91e-15	76.3	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1HX4S@117743|Flavobacteriia,23G8F@178469|Arenibacter	976|Bacteroidetes	M	Asp/Glu/Hydantoin racemase	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_64787_1	1265313.HRUBRA_00595	1.23e-08	63.2	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg,dCache_1
k59_173221_1	2340.JV46_12910	2.53e-149	439.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1J5CY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_4019_1	1165841.SULAR_08467	6.53e-61	191.0	COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria	1224|Proteobacteria	M	COG3637 Opacity protein and related surface antigens	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
k59_186786_1	1165841.SULAR_05128	3.63e-163	479.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_17412_1	1408473.JHXO01000006_gene1027	1.93e-55	180.0	COG0664@1|root,COG0664@2|Bacteria,4P3ES@976|Bacteroidetes	976|Bacteroidetes	T	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_24094_1	83406.HDN1F_33940	4.9e-13	69.3	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1J79J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG1070 Sugar (pentulose and hexulose) kinases	ygcE	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
k59_24094_2	589865.DaAHT2_0732	1.02e-63	217.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
k59_98991_1	283699.D172_2866	1.19e-24	108.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,2Q2B1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
k59_10550_1	795359.TOPB45_1008	4.9e-106	333.0	COG0542@1|root,COG0542@2|Bacteria,2GGRY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_112099_1	395493.BegalDRAFT_1665	3.13e-94	288.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_207331_1	3988.XP_002525389.1	4.25e-50	181.0	COG1078@1|root,KOG2681@2759|Eukaryota,37I91@33090|Viridiplantae,3GNMH@35493|Streptophyta,4JREJ@91835|fabids	35493|Streptophyta	S	4Fe-4S single cluster domain	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,HD,Radical_SAM
k59_159782_1	1484460.JSWG01000015_gene905	2.86e-41	151.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_159782_2	1442599.JAAN01000005_gene943	7.86e-05	43.9	COG3197@1|root,COG3197@2|Bacteria,1QSIT@1224|Proteobacteria,1RW0B@1236|Gammaproteobacteria,1X8QU@135614|Xanthomonadales	135614|Xanthomonadales	P	Cytochrome oxidase maturation protein	-	-	-	-	-	-	-	-	-	-	-	-	FixS
k59_159782_3	880071.Fleli_1082	2.14e-08	58.9	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_78428_1	1123399.AQVE01000027_gene39	8.05e-23	97.8	28MPZ@1|root,2ZAYZ@2|Bacteria,1R6T8@1224|Proteobacteria,1SA9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105679_1	1210884.HG799473_gene14973	1.6e-45	165.0	COG3464@1|root,COG3464@2|Bacteria,2IZV3@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Uncharacterised protein family (UPF0236)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10551_1	867900.Celly_2336	2.41e-05	49.7	COG1649@1|root,COG1649@2|Bacteria,4NGFW@976|Bacteroidetes,1HYGF@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015,GHL10
k59_10551_2	742767.HMPREF9456_00861	4.41e-41	148.0	COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,2G37K@200643|Bacteroidia,22Y1C@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_4036_1	1165841.SULAR_09219	1.08e-116	340.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_85381_1	331678.Cphamn1_0773	5.56e-29	106.0	COG2963@1|root,COG2963@2|Bacteria,1FF9V@1090|Chlorobi	1090|Chlorobi	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_85381_2	643562.Daes_0415	8.75e-14	71.2	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,42NJR@68525|delta/epsilon subdivisions,2WKAM@28221|Deltaproteobacteria,2M94G@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
k59_112102_1	797302.Halru_0402	7.55e-30	118.0	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,23SRK@183963|Halobacteria	183963|Halobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_78431_1	123899.JPQP01000006_gene742	7.08e-18	85.1	COG1132@1|root,COG4988@1|root,COG1132@2|Bacteria,COG4988@2|Bacteria,1MUBM@1224|Proteobacteria,2W0T3@28216|Betaproteobacteria,3T3CJ@506|Alcaligenaceae	28216|Betaproteobacteria	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
k59_186795_2	441769.ABFU01000070_gene2054	2.04e-36	137.0	COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,4HC07@91061|Bacilli,1ZQUF@1386|Bacillus	91061|Bacilli	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_71568_1	1188256.BASI01000005_gene2182	1.29e-46	168.0	COG0323@1|root,COG0323@2|Bacteria,1R57G@1224|Proteobacteria,2UEXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA mismatch repair	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
k59_207340_1	1304883.KI912532_gene1755	9.18e-07	53.5	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,2KUGP@206389|Rhodocyclales	206389|Rhodocyclales	S	ABC transporter	abcZ	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_146341_1	395493.BegalDRAFT_2820	2.05e-94	307.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_71570_1	1121007.AUML01000003_gene2562	2.38e-58	188.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,1HZ2R@117743|Flavobacteriia,2YHHT@290174|Aquimarina	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_71570_2	1443665.JACA01000027_gene3907	1.18e-13	64.7	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1I51F@117743|Flavobacteriia,2YK5F@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
k59_193739_1	420662.Mpe_A1227	5.26e-15	72.4	2AHZN@1|root,318CZ@2|Bacteria,1Q06K@1224|Proteobacteria,2W4WA@28216|Betaproteobacteria,1KNW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_193739_2	377629.TERTU_3743	6.93e-05	43.9	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,2PN2A@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	aglR	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_85387_1	631362.Thi970DRAFT_01520	2.35e-66	205.0	2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,1S4WN@1236|Gammaproteobacteria,1WYAX@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74108_1	1197719.A464_4134	2.45e-13	75.1	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,3ZKTM@590|Salmonella	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iECS88_1305.ECS88_4396	5_nucleotid_C,Metallophos
k59_189518_1	2340.JV46_19210	2.99e-123	377.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08483,ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_40335_1	1168289.AJKI01000046_gene899	9.2e-64	207.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_182822_1	443152.MDG893_10916	6.27e-49	172.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,465TI@72275|Alteromonadaceae	1236|Gammaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
k59_182825_1	62928.azo1413	2.49e-37	138.0	COG1034@1|root,COG1034@2|Bacteria,1QVC7@1224|Proteobacteria,2VI6U@28216|Betaproteobacteria,2KVII@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	hoxU	-	1.12.1.2	ko:K18006	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
k59_40347_1	1089552.KI911559_gene1869	3.46e-104	335.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,2JQA4@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
k59_142328_1	870187.Thini_1858	4.25e-52	186.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0753 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2309
k59_196536_1	411154.GFO_3359	4.86e-97	299.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_40349_1	765913.ThidrDRAFT_2759	1.8e-107	323.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,1RQ8X@1236|Gammaproteobacteria,1WW6F@135613|Chromatiales	135613|Chromatiales	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_196545_2	1192868.CAIU01000033_gene4184	4.29e-23	93.6	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VFYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_189550_1	443143.GM18_0366	2e-07	53.1	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,43TEH@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_40360_1	78898.MVEG_01754T0	1.05e-37	139.0	COG0624@1|root,KOG2275@2759|Eukaryota,38BH3@33154|Opisthokonta,3NUCZ@4751|Fungi	4751|Fungi	E	Belongs to the peptidase M20A family	-	GO:0003674,GO:0003824,GO:0006508,GO:0006518,GO:0006575,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009636,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0042219,GO:0042221,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0070011,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1990748	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_189556_1	768671.ThimaDRAFT_1748	3.29e-94	282.0	COG0650@1|root,COG0650@2|Bacteria,1QE37@1224|Proteobacteria,1RZJC@1236|Gammaproteobacteria,1WWZT@135613|Chromatiales	135613|Chromatiales	C	pfam nadh	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_74134_1	765910.MARPU_01575	1.48e-10	66.6	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,1X2B5@135613|Chromatiales	135613|Chromatiales	NU	PFAM Sulphatase-modifying factor	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_128627_1	1236959.BAMT01000001_gene1406	1e-62	205.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KM17@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_189563_2	797209.ZOD2009_13466	2.39e-07	54.3	arCOG10603@1|root,arCOG10603@2157|Archaea,2XWSN@28890|Euryarchaeota,23VC9@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189602_1	686340.Metal_3143	4.13e-06	50.4	COG3293@1|root,COG3385@1|root,COG3293@2|Bacteria,COG3385@2|Bacteria,1RBFK@1224|Proteobacteria,1S22S@1236|Gammaproteobacteria,1XGGK@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
k59_176526_3	1184609.KILIM_004_01350	8.39e-11	58.5	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_108723_1	314285.KT71_17336	1.12e-90	270.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,1J6BC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_149394_1	4096.XP_009778652.1	4.15e-156	440.0	COG1845@1|root,KOG4664@2759|Eukaryota,37QER@33090|Viridiplantae,3G8C5@35493|Streptophyta	35493|Streptophyta	C	cytochrome c oxidase subunit 3	cox3	-	-	ko:K02262	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX3
k59_210459_1	211586.SO_2129	6.52e-81	259.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,2QCBP@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_156241_2	314285.KT71_03157	2.76e-82	261.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1JBW7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_20701_1	1173264.KI913949_gene1554	9.37e-26	109.0	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,1G2I8@1117|Cyanobacteria,1H8CU@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction protein with nacht domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,GUN4,NACHT
k59_176528_1	879212.DespoDRAFT_00289	2.88e-12	66.2	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_176528_2	879212.DespoDRAFT_01215	2.71e-54	180.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_108726_2	870187.Thini_0240	3.54e-43	142.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,1T0H0@1236|Gammaproteobacteria,461BU@72273|Thiotrichales	72273|Thiotrichales	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_169725_1	2340.JV46_08110	2.02e-93	298.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1J4RE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_4025	PEPcase
k59_7073_1	290315.Clim_1359	2.57e-53	198.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	recB	-	3.1.11.5,3.6.4.12	ko:K03406,ko:K03582,ko:K16898	ko02020,ko02030,ko03440,map02020,map02030,map03440	-	-	-	ko00000,ko00001,ko01000,ko02035,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_61351_2	1156919.QWC_12533	2.46e-18	88.2	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria,3T7Q0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k59_108728_1	1443665.JACA01000003_gene839	2.15e-122	369.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia,2YI85@290174|Aquimarina	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k59_196904_1	296587.XP_002507372.1	0.000268	50.1	COG5184@1|root,KOG1426@2759|Eukaryota	2759|Eukaryota	DZ	guanyl-nucleotide exchange factor activity	RCCD1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
k59_13882_1	1165841.SULAR_01315	2.11e-48	162.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2YMHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_13882_2	1165841.SULAR_01310	1.33e-47	162.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YQ1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169727_1	1175654.A0A0S0N8I3_9CAUD	2.82e-24	103.0	4QCWX@10239|Viruses,4QYGT@35237|dsDNA viruses  no RNA stage,4QU1G@28883|Caudovirales,4QMA7@10699|Siphoviridae	10699|Siphoviridae	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210470_2	1121875.KB907558_gene545	8.36e-63	204.0	2CC76@1|root,3435K@2|Bacteria,4P48D@976|Bacteroidetes,1I9GK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_163015_1	715451.ambt_17675	6.47e-60	201.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1R97Q@1224|Proteobacteria,1RRDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_190150_1	4081.Solyc00g013130.2.1	9.45e-72	223.0	COG1007@1|root,KOG4668@2759|Eukaryota,37KKM@33090|Viridiplantae,3GCSG@35493|Streptophyta,44UBZ@71274|asterids	35493|Streptophyta	C	Proton-conducting membrane transporter	nad2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_135840_1	159450.NH14_30870	6.68e-47	172.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,Response_reg
k59_129030_2	1089550.ATTH01000001_gene2221	1.07e-07	55.1	COG0657@1|root,COG0657@2|Bacteria,4NGAF@976|Bacteroidetes,1FJAQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Protein of unknown function (DUF1460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460
k59_149420_1	1237149.C900_05403	7.7e-08	59.7	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
k59_7084_1	1168034.FH5T_11410	5.08e-114	339.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,2FMYJ@200643|Bacteroidia	976|Bacteroidetes	S	RmuC domain protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_348_1	697282.Mettu_3699	1.74e-28	119.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1XESZ@135618|Methylococcales	135618|Methylococcales	Q	TIGRFAM Amino acid adenylation	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_176556_1	1122599.AUGR01000006_gene3756	2.33e-15	72.4	COG2703@1|root,COG2703@2|Bacteria,1N3PI@1224|Proteobacteria,1SB9K@1236|Gammaproteobacteria,1XKI5@135619|Oceanospirillales	135619|Oceanospirillales	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_176556_2	1165841.SULAR_06613	8.06e-84	254.0	COG4654@1|root,COG4654@2|Bacteria,1R1K5@1224|Proteobacteria,42WVZ@68525|delta/epsilon subdivisions,2YQRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_54566_1	1165841.SULAR_02508	3.18e-21	88.6	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42QT6@68525|delta/epsilon subdivisions,2YR4C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_126130_1	620914.JH621255_gene559	1.01e-78	240.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,2YK2V@290174|Aquimarina	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_119594_1	1047013.AQSP01000118_gene1236	6.1e-81	267.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_133111_1	1137281.D778_01913	2.38e-68	226.0	COG0739@1|root,COG0739@2|Bacteria,4NIH1@976|Bacteroidetes,1HZT8@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_153312_1	2340.JV46_04090	2.44e-97	301.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k59_200700_1	749222.Nitsa_0492	1.27e-31	118.0	COG0745@1|root,COG0745@2|Bacteria,1QZNH@1224|Proteobacteria,42SJZ@68525|delta/epsilon subdivisions,2YPIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_17763_1	1121285.AUFK01000006_gene1940	3.14e-06	45.1	2A51Y@1|root,30TQ9@2|Bacteria,4PHEW@976|Bacteroidetes,1IM3G@117743|Flavobacteriia,3ZU37@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78655_1	697282.Mettu_2544	1.58e-23	95.1	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_44566_1	2340.JV46_27640	2.47e-77	240.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1J4F2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_44566_2	1442599.JAAN01000012_gene138	1.39e-08	55.8	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1X373@135614|Xanthomonadales	135614|Xanthomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_139645_1	1168034.FH5T_07370	1.15e-51	167.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,2FP84@200643|Bacteroidia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_139645_2	1168034.FH5T_07375	9.18e-23	93.6	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_160110_1	519989.ECTPHS_12607	5.76e-38	133.0	COG2452@1|root,COG2452@2|Bacteria,1QV30@1224|Proteobacteria,1S2GA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,Resolvase
k59_166673_1	1504823.CCMM01000013_gene2856	6.31e-12	70.9	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	3.4.21.72	ko:K01347,ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko02000,ko02044	1.B.12.3	-	-	DUF5011,F5_F8_type_C,Flg_new,LRR_5,NPCBM,Peptidase_M60
k59_44572_2	1121921.KB898715_gene42	1.09e-46	151.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	spsF	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_92367_1	1165841.SULAR_01315	2.17e-107	316.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2YMHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_112316_1	1235803.C825_01379	3.01e-91	280.0	COG1294@1|root,COG1294@2|Bacteria,4NHZU@976|Bacteroidetes,2FMIN@200643|Bacteroidia,22W6V@171551|Porphyromonadaceae	976|Bacteroidetes	C	Cytochrome C oxidase assembly protein	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_126145_1	1165841.SULAR_08919	1e-96	285.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M6H@68525|delta/epsilon subdivisions,2YNC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
k59_180176_1	412597.AEPN01000014_gene2364	1.05e-11	65.5	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria,2PWFR@265|Paracoccus	28211|Alphaproteobacteria	P	ABC transporter permease	-	-	-	ko:K15552	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
k59_173442_1	1168034.FH5T_15545	5.16e-137	409.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,2FMEB@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_10787_1	991905.SL003B_1434	5.62e-54	180.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,4BPRI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_10787_2	1265507.KB899636_gene2128	2.18e-46	154.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,1Y45I@135624|Aeromonadales	135624|Aeromonadales	K	Lrp/AsnC ligand binding domain	lrp	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k59_173774_1	237368.SCABRO_02540	3.48e-49	164.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
k59_11074_1	1120956.JHZK01000005_gene2260	5.3e-20	90.1	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,1JN2E@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
k59_4740_1	1379270.AUXF01000001_gene2203	1.29e-08	62.0	COG1330@1|root,COG1330@2|Bacteria,1ZUMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Exodeoxyribonuclease V, gamma subunit	-	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k59_72168_1	472759.Nhal_0922	1.64e-59	197.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1WWQM@135613|Chromatiales	135613|Chromatiales	P	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_173780_1	1411123.JQNH01000001_gene1604	4.44e-113	329.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type polar amino acid transport system ATPase component	aapP	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k59_173780_2	1118153.MOY_07762	1.34e-13	69.3	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,1RPJR@1236|Gammaproteobacteria,1XIG0@135619|Oceanospirillales	135619|Oceanospirillales	P	Amino acid ABC transporter, permease	aapM	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_78977_1	1165841.SULAR_00285	1.88e-101	306.0	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,42VNT@68525|delta/epsilon subdivisions,2YRXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_78977_2	1165841.SULAR_00290	3.79e-14	71.2	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_180542_1	485918.Cpin_0801	3.46e-43	146.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_133530_1	1121438.JNJA01000001_gene2084	4.7e-44	162.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_126526_1	397288.C806_04746	2.47e-24	110.0	COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,25D02@186801|Clostridia,27TNM@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Mu-transpos_C,rve
k59_200966_1	2340.JV46_26650	4.19e-126	371.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,1RPND@1236|Gammaproteobacteria,1J945@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	TraB family	traB	-	-	-	-	-	-	-	-	-	-	-	TraB
k59_44982_1	318586.Pden_3333	2.94e-85	253.0	COG0309@1|root,COG0309@2|Bacteria,1RDJ4@1224|Proteobacteria,2U7HE@28211|Alphaproteobacteria,2PX0J@265|Paracoccus	28211|Alphaproteobacteria	O	Transposase, IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k59_44982_2	318586.Pden_2059	1.04e-75	227.0	COG3293@1|root,COG3293@2|Bacteria,1RDDI@1224|Proteobacteria,2U7E3@28211|Alphaproteobacteria,2PX6M@265|Paracoccus	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k59_160498_1	2340.JV46_15520	1.6e-62	202.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_126527_1	1459636.NTE_01234	5.89e-103	309.0	COG1013@1|root,arCOG01599@2157|Archaea,41SAB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k59_214317_2	547144.HydHO_1377	9.66e-32	114.0	COG3411@1|root,COG3411@2|Bacteria,2G541@200783|Aquificae	200783|Aquificae	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
k59_214317_3	765910.MARPU_12410	6.28e-09	54.7	COG1146@1|root,COG1146@2|Bacteria,1QW5F@1224|Proteobacteria,1T4WS@1236|Gammaproteobacteria,1WYJJ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM ferredoxin III	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_119934_1	1121405.dsmv_1440	1.79e-29	117.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NHP@68525|delta/epsilon subdivisions,2X6U1@28221|Deltaproteobacteria,2MHMI@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_4759_1	1047013.AQSP01000105_gene1439	4.78e-40	148.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_167008_1	1168034.FH5T_00380	1.16e-90	270.0	2AIA7@1|root,318R1@2|Bacteria,4NQPK@976|Bacteroidetes,2FPYF@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF5063
k59_200977_1	487796.Flav2ADRAFT_1114	7.07e-06	53.9	COG2931@1|root,COG3210@1|root,COG3266@1|root,COG4625@1|root,COG4733@1|root,COG5644@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,COG5644@2|Bacteria	2|Bacteria	H	endopeptidase inhibitor activity	yddG	-	3.4.24.40	ko:K01406,ko:K03201,ko:K07451,ko:K13613,ko:K19360	ko01503,ko03070,map01503,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01004,ko01008,ko02044,ko02048,ko03036	3.A.7	-	-	DUF4335,HemolysinCabind,Phage-tail_3
k59_86013_1	296591.Bpro_4825	1.17e-16	82.0	COG0745@1|root,COG0784@1|root,COG2204@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4AJX3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_86013_2	1192034.CAP_4540	4.31e-38	147.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,438BB@68525|delta/epsilon subdivisions,2X3KN@28221|Deltaproteobacteria,2YWFV@29|Myxococcales	1224|Proteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08282,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
k59_180552_1	203122.Sde_3138	2.74e-53	180.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4655Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830	Aminotran_1_2
k59_180555_1	1340493.JNIF01000003_gene4366	1.59e-10	63.5	COG0345@1|root,COG0345@2|Bacteria,3Y41B@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_180555_2	699246.HMPREF0868_0252	0.000191	47.4	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,2689N@186813|unclassified Clostridiales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k59_106442_1	1168034.FH5T_11190	2.44e-68	213.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,2FWBE@200643|Bacteroidia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
k59_133546_1	1165841.SULAR_01843	6.21e-55	175.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,42U84@68525|delta/epsilon subdivisions,2YPVG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_133546_2	1165841.SULAR_01848	8.89e-50	163.0	2BVAM@1|root,32QQF@2|Bacteria,1Q4S6@1224|Proteobacteria,42ZRM@68525|delta/epsilon subdivisions,2YRRP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_167012_1	130081.XP_005705031.1	4.4e-144	425.0	COG0055@1|root,COG0355@1|root,KOG1350@2759|Eukaryota,KOG1758@2759|Eukaryota	2759|Eukaryota	C	proton-transporting ATP synthase activity, rotational mechanism	ATP5D	GO:0000275,GO:0002376,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005754,GO:0005756,GO:0005759,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008150,GO:0008152,GO:0008270,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009620,GO:0009628,GO:0009814,GO:0009817,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010287,GO:0010319,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016043,GO:0016310,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031976,GO:0031977,GO:0031984,GO:0032991,GO:0033178,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042221,GO:0042407,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0042776,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0044877,GO:0045087,GO:0045259,GO:0045261,GO:0045267,GO:0045269,GO:0046034,GO:0046390,GO:0046483,GO:0046688,GO:0046689,GO:0046872,GO:0046907,GO:0046914,GO:0046933,GO:0050832,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0055035,GO:0055085,GO:0055086,GO:0061024,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098542,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098807,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542	3.6.3.14	ko:K02112,ko:K02114,ko:K02133,ko:K02134,ko:K14573	ko00190,ko00195,ko01100,ko03008,ko04714,ko05010,ko05012,ko05016,map00190,map00195,map01100,map03008,map04714,map05010,map05012,map05016	M00157,M00158	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko03009	3.A.2.1	-	iMM904.YDL004W,iND750.YDL004W	ATP-synt_DE,ATP-synt_DE_N,ATP-synt_ab,ATP-synt_ab_N
k59_139972_2	1121923.GPUN_1530	1.18e-07	58.9	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,465EM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_99577_1	706587.Desti_0274	2.36e-43	160.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MR2Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_45000_1	445696.E3ST05_9CAUD	3.62e-72	231.0	4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses  no RNA stage,4QQ4N@28883|Caudovirales,4QIBN@10662|Myoviridae	10662|Myoviridae	S	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_106446_1	269799.Gmet_2905	2.3e-167	482.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_4777_1	1140.Synpcc7942_0725	2.57e-45	166.0	COG1061@1|root,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria,1H08U@1129|Synechococcus	1117|Cyanobacteria	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,ResIII
k59_139977_1	1165841.SULAR_10254	3.01e-14	71.2	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_139977_2	1165841.SULAR_10259	4.8e-40	132.0	COG0828@1|root,COG0828@2|Bacteria,1Q61C@1224|Proteobacteria,42VSR@68525|delta/epsilon subdivisions,2YQAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_180568_1	525903.Taci_0768	2.85e-45	163.0	COG1921@1|root,COG1921@2|Bacteria,3TA3F@508458|Synergistetes	508458|Synergistetes	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
k59_4780_1	387093.SUN_1842	4.48e-49	177.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_173818_1	335543.Sfum_2371	2.63e-20	97.8	COG1572@1|root,COG1572@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
k59_99590_1	2340.JV46_05750	1.29e-77	249.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1J523@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_147040_1	909663.KI867150_gene2465	2.95e-122	374.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,42PRE@68525|delta/epsilon subdivisions,2WJRD@28221|Deltaproteobacteria,2MRGT@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_86036_1	1056820.KB900674_gene2674	7.64e-54	185.0	COG3488@1|root,COG3488@2|Bacteria,1PFIC@1224|Proteobacteria,1SAYQ@1236|Gammaproteobacteria,2PPSX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
k59_198601_1	1121405.dsmv_3405	3.04e-117	348.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_96811_1	313596.RB2501_08060	5.07e-72	231.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia	976|Bacteroidetes	J	ribonuclease G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_103552_1	2340.JV46_18940	5.87e-32	121.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1J79H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	General secretion pathway protein J	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
k59_103552_2	2340.JV46_18950	6.62e-14	71.2	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,1SASH@1236|Gammaproteobacteria,1JAPT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Type II secretion system (T2SS), protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_15462_1	1165841.SULAR_00665	1.42e-47	159.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_15462_2	1004785.AMBLS11_18845	1.81e-82	266.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	ko:K16076,ko:K18093	ko01501,ko02020,map01501,map02020	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.1.4,1.B.1.1.5,1.B.25.1.1	-	-	OprD,Porin_4
k59_8481_1	2340.JV46_23760	5.19e-50	171.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1J4G6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280	Aldedh
k59_191676_1	1168034.FH5T_12655	1.93e-80	251.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,2FNYN@200643|Bacteroidia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_42457_1	313596.RB2501_15954	5.48e-84	254.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_177957_1	1168034.FH5T_08960	2.67e-78	245.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,2FPJR@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_76350_1	760192.Halhy_1458	3.44e-05	52.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NJX0@976|Bacteroidetes,1J053@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,Y_Y_Y
k59_63265_2	1165841.SULAR_00990	1.62e-155	440.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	forB2	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_137630_1	616991.JPOO01000001_gene3325	2.16e-61	197.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HZ28@117743|Flavobacteriia,23IF4@178469|Arenibacter	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_205591_1	745776.DGo_CA0097	3.79e-26	110.0	COG1975@1|root,COG1975@2|Bacteria,1WIZE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	XdhC Rossmann domain	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
k59_97170_2	948565.AFFP02000031_gene1562	1.45e-36	130.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1Y8M4@135625|Pasteurellales	135625|Pasteurellales	D	Nucleotide-binding protein implicated in inhibition of septum formation	Z012_09390	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_8908_1	1165841.SULAR_00425	8.19e-77	246.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_42734_1	886293.Sinac_2040	1.13e-27	114.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_198962_1	1122621.ATZA01000006_gene747	0.000477	50.8	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1J0JM@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	todS_10	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_49832_2	749222.Nitsa_0520	3.58e-101	305.0	28K4S@1|root,2Z9TM@2|Bacteria,1N4AQ@1224|Proteobacteria,42PSN@68525|delta/epsilon subdivisions,2YMP7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42740_1	740709.A10D4_01220	4.04e-53	182.0	COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,2QG93@267893|Idiomarinaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_124202_2	1173027.Mic7113_4926	1.48e-13	67.8	COG3668@1|root,COG3668@2|Bacteria,1G8WD@1117|Cyanobacteria,1HDM2@1150|Oscillatoriales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_137648_1	1461693.ATO10_11967	6.33e-08	58.9	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,2U473@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
k59_117551_1	2340.JV46_25840	1.27e-95	300.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1J526@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_8924_1	566466.NOR53_923	1.48e-38	132.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1J6Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_8924_2	1279017.AQYJ01000029_gene3828	1.2e-18	79.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,468RS@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	cspD	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_76651_1	1165841.SULAR_04267	5.64e-117	347.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2YMRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_49850_1	314278.NB231_12666	2.44e-37	137.0	COG4715@1|root,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
k59_164779_1	2340.JV46_08120	2.34e-86	264.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1J5DJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_137658_1	1165841.SULAR_03657	3.88e-22	95.9	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_137658_2	1165841.SULAR_03647	1.3e-24	102.0	COG0790@1|root,COG0790@2|Bacteria,1NY7Z@1224|Proteobacteria,42T5I@68525|delta/epsilon subdivisions,2YPQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_63277_1	1165841.SULAR_09424	3.01e-72	229.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2YMSR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_124223_1	857087.Metme_0332	8.02e-34	129.0	COG1373@1|root,COG1373@2|Bacteria,1R4HK@1224|Proteobacteria,1SSIT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase (AAA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_198991_1	1385515.N791_01430	4.46e-69	218.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1X387@135614|Xanthomonadales	135614|Xanthomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_36001_1	2340.JV46_23290	7.52e-40	137.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1J5QA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_36001_2	2340.JV46_23830	3.06e-32	117.0	2DMN0@1|root,32SKB@2|Bacteria,1N2XU@1224|Proteobacteria,1T0A7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
k59_15818_1	1165841.SULAR_05933	3.35e-127	372.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2YMUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_8944_1	225849.swp_1319	5.82e-35	123.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,2Q9YM@267890|Shewanellaceae	1236|Gammaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k59_8944_2	1415779.JOMH01000001_gene3024	9.08e-20	89.7	COG2010@1|root,COG2885@1|root,COG2010@2|Bacteria,COG2885@2|Bacteria,1RBXJ@1224|Proteobacteria,1S2QH@1236|Gammaproteobacteria,1X68M@135614|Xanthomonadales	135614|Xanthomonadales	CM	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,OmpA
k59_144392_1	387093.SUN_1138	1.14e-54	184.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_144392_2	1165841.SULAR_04262	0.000167	41.2	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_212330_1	1129794.C427_0327	1.12e-47	160.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,464M1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_137665_1	999141.GME_15952	7.2e-13	65.9	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XJUI@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
k59_137665_2	743720.Psefu_3451	7.42e-31	113.0	COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1YYUR@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1820)	IV02_29925	-	-	-	-	-	-	-	-	-	-	-	DUF1820
k59_97216_1	533247.CRD_01730	1.42e-80	255.0	COG1171@1|root,COG1171@2|Bacteria,1G22X@1117|Cyanobacteria,1HJWD@1161|Nostocales	1117|Cyanobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ilvA	PALP,Thr_dehydrat_C
k59_198998_1	1168034.FH5T_16960	4.16e-89	269.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_192038_1	1247726.MIM_c10680	2.54e-09	58.9	COG3646@1|root,COG3646@2|Bacteria,1PURP@1224|Proteobacteria,2VWP7@28216|Betaproteobacteria,3T7Y1@506|Alcaligenaceae	28216|Betaproteobacteria	S	Phage regulatory protein Rha (Phage_pRha)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_pRha
k59_49875_1	15368.BRADI3G27332.1	7.32e-07	50.1	2CMAK@1|root,2QPT8@2759|Eukaryota,37MKA@33090|Viridiplantae,3GD5I@35493|Streptophyta,3KY9T@4447|Liliopsida,3IAPE@38820|Poales	35493|Streptophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N
k59_103969_3	402612.FP2450	2.72e-28	105.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia,2NVXP@237|Flavobacterium	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_22583_1	1577887.JSYG01000018_gene1851	8.2e-71	238.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria,2JDVI@204037|Dickeya	1236|Gammaproteobacteria	L	DNA primase catalytic core domain	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
k59_8954_1	313603.FB2170_09231	6.64e-29	120.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia,2PGSE@252356|Maribacter	976|Bacteroidetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
k59_69932_1	1172185.KB911512_gene5191	2.51e-26	108.0	COG1073@1|root,COG1073@2|Bacteria,2HHN0@201174|Actinobacteria,4FZAE@85025|Nocardiaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
k59_185168_1	545276.KB898728_gene137	5.43e-55	180.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_69934_1	3880.AES95170	1.95e-42	152.0	COG0169@1|root,KOG0692@2759|Eukaryota,37S9N@33090|Viridiplantae,3GFW7@35493|Streptophyta,4JHSX@91835|fabids	35493|Streptophyta	E	3-dehydroquinate synthase	-	GO:0003674,GO:0003824,GO:0003856,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0012505,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019632,GO:0019752,GO:0031410,GO:0031982,GO:0031984,GO:0032787,GO:0033587,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044431,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:0097708,GO:0098791,GO:1901576,GO:1901615,GO:1901617	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_103971_1	247639.MGP2080_01861	1.21e-05	50.8	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,1J4FA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_15838_1	1165841.SULAR_03103	5.05e-154	446.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_42778_1	349163.Acry_1700	2.91e-80	265.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2JQ1S@204441|Rhodospirillales	204441|Rhodospirillales	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_205655_2	698737.SLGD_00695	3.16e-05	44.7	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,4GZXI@90964|Staphylococcaceae	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_199011_1	1168034.FH5T_07430	1.88e-119	349.0	COG1145@1|root,COG1145@2|Bacteria,4NI4X@976|Bacteroidetes,2FN3Z@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k59_22593_1	177437.HRM2_10810	5.12e-11	61.6	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2MHVV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_22593_2	439235.Dalk_3405	1.76e-65	201.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2WP2B@28221|Deltaproteobacteria,2MK4J@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1897	PRA-CH,PRA-PH
k59_171723_1	765912.Thimo_2326	2.82e-52	190.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
k59_42784_1	1165841.SULAR_08157	1.51e-11	61.6	COG2259@1|root,COG2259@2|Bacteria,1RKEE@1224|Proteobacteria,42SF5@68525|delta/epsilon subdivisions,2YPGK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_46192_2	1027273.GZ77_05805	5.87e-10	56.6	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
k59_12533_1	926554.KI912645_gene1634	4.63e-10	66.2	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_168574_1	2340.JV46_17580	1.6e-71	229.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4KP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_168574_2	450851.PHZ_c1731	1.4e-05	46.2	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,2KFZV@204458|Caulobacterales	204458|Caulobacterales	T	Signal transduction histidine kinase, nitrogen specific	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k59_67018_1	378806.STAUR_0820	1.17e-54	193.0	COG0001@1|root,COG1020@1|root,COG2141@1|root,COG3319@1|root,COG3321@1|root,COG0001@2|Bacteria,COG1020@2|Bacteria,COG2141@2|Bacteria,COG3319@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,43E1T@68525|delta/epsilon subdivisions,2X7HJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Beta- ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Bac_luciferase,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
k59_60242_1	1165841.SULAR_04117	6.34e-26	105.0	COG1196@1|root,COG1196@2|Bacteria,1QUJ1@1224|Proteobacteria,42P7I@68525|delta/epsilon subdivisions,2YMKS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
k59_60242_2	1165841.SULAR_04122	2.69e-63	194.0	COG2010@1|root,COG2010@2|Bacteria,1Q2E5@1224|Proteobacteria,42VHQ@68525|delta/epsilon subdivisions,2YQ7N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_46560_1	1144664.F973_01735	3.9e-51	181.0	COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,1RY0B@1236|Gammaproteobacteria,3NMG0@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67020_1	387093.SUN_2274	2.06e-75	241.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_6105_1	309801.trd_0700	4.26e-08	63.5	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia	189775|Thermomicrobia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_181952_1	1165841.SULAR_06118	1.04e-40	145.0	COG4775@1|root,COG4775@2|Bacteria,1R536@1224|Proteobacteria	1224|Proteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_73400_1	931627.MycrhDRAFT_2921	1.22e-26	110.0	COG0247@1|root,COG3266@1|root,COG0247@2|Bacteria,COG3266@2|Bacteria,2GJ7M@201174|Actinobacteria,232WS@1762|Mycobacteriaceae	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_73400_2	1267533.KB906734_gene3884	2.38e-43	150.0	COG2025@1|root,COG2025@2|Bacteria,3Y3JE@57723|Acidobacteria,2JM9U@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_107830_1	999547.KI421500_gene3534	1e-52	184.0	COG0769@1|root,COG0769@2|Bacteria,1R52S@1224|Proteobacteria,2U1XC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mur ligase family, glutamate ligase domain	-	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_6107_1	50960.LS81_10000	1.96e-17	86.7	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_141272_1	1265845.PWEIH_04191	2.04e-26	107.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,26K4I@186820|Listeriaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_87186_1	1449126.JQKL01000050_gene2698	1.24e-42	142.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,26987@186813|unclassified Clostridiales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_113803_1	1175654.A0A0S0N897_9CAUD	1.08e-33	130.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae	10699|Siphoviridae	S	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175261_1	876044.IMCC3088_1331	1.06e-69	214.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1J4K8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050	Sod_Fe_C,Sod_Fe_N
k59_195700_1	338963.Pcar_2426	1.72e-177	533.0	COG5114@1|root,COG5114@2|Bacteria,1QV7J@1224|Proteobacteria	1224|Proteobacteria	B	positive regulation of histone acetylation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94118_1	72664.XP_006405523.1	5.88e-256	701.0	28IP8@1|root,2QR09@2759|Eukaryota,37PUB@33090|Viridiplantae,3GEYD@35493|Streptophyta,3HX10@3699|Brassicales	35493|Streptophyta	C	Photosystem II (PSII) is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1 D2 (PsbA PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors	psbA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0010287,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	1.10.3.9	ko:K02703,ko:K20000	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko03016	-	-	-	Photo_RC
k59_94118_2	4577.GRMZM5G836994_P01	3.7e-16	79.0	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,3KWRZ@4447|Liliopsida,3IFBD@38820|Poales	35493|Streptophyta	J	Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_60257_1	395493.BegalDRAFT_1538	9.14e-70	226.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZTS@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Sigma54_activat
k59_202409_1	2340.JV46_23230	1.69e-30	117.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1J4NC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_12551_1	1163617.SCD_n01782	0.000152	43.5	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
k59_113811_1	1168034.FH5T_00615	7.19e-27	103.0	COG2730@1|root,COG2730@2|Bacteria,4NXWZ@976|Bacteroidetes,2FZGH@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73408_1	1165841.SULAR_10349	1.3e-127	383.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_141276_1	2340.JV46_28920	1.54e-35	121.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SCFA@1236|Gammaproteobacteria,1J6VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k59_141276_2	1122201.AUAZ01000003_gene2050	4.37e-62	202.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,466ZU@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k59_127826_1	2340.JV46_14810	6.01e-119	353.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1J4V5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_39356_1	237368.SCABRO_03144	6.03e-14	77.4	COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_209275_1	172088.AUGA01000071_gene7567	4.46e-06	51.6	COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Caudovirus prohead serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_capsid
k59_127830_1	595460.RRSWK_03616	8.16e-61	200.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	DUF4976,Sulfatase
k59_181976_1	1304275.C41B8_08790	1.01e-16	81.6	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	permease	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_181976_2	1123502.AQXD01000001_gene1176	3.94e-10	60.8	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1X46N@135614|Xanthomonadales	135614|Xanthomonadales	S	permease	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_113814_2	349520.PPE_03685	1.57e-60	194.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,26RHP@186822|Paenibacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_141280_1	5970.XP_009159355.1	1.25e-25	105.0	COG0450@1|root,KOG0854@2759|Eukaryota,38CN4@33154|Opisthokonta,3NW6E@4751|Fungi,3QMF7@4890|Ascomycota,20KJS@147545|Eurotiomycetes,3MYGP@451870|Chaetothyriomycetidae	4751|Fungi	O	Peroxiredoxin (alkyl hydroperoxide reductase subunit C)	-	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_19606_1	1121405.dsmv_3682	6.49e-13	69.7	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_154949_1	1168034.FH5T_10135	9.09e-09	55.5	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_209277_1	2340.JV46_09630	6.3e-183	518.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_26194_1	313596.RB2501_12874	3.67e-34	122.0	2DM5T@1|root,31U0Y@2|Bacteria,4NMMA@976|Bacteroidetes,1I0IR@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
k59_26194_2	983548.Krodi_2794	3.86e-23	94.4	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1HXV5@117743|Flavobacteriia,37DKS@326319|Dokdonia	976|Bacteroidetes	M	Cytidylyltransferase	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_161837_1	7668.SPU_003026-tr	7.16e-10	66.6	2D1AE@1|root,2SHBM@2759|Eukaryota,3AFP7@33154|Opisthokonta,3BY0Y@33208|Metazoa,3DET1@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17
k59_121210_1	391603.FBALC1_16132	8.16e-28	114.0	2E3AK@1|root,2ZC4K@2|Bacteria,4NMMM@976|Bacteroidetes,1I1F6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60275_1	1123518.ARWI01000001_gene1637	1.19e-31	123.0	COG2834@1|root,COG2834@2|Bacteria,1R8JU@1224|Proteobacteria,1SKB0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215789_1	666681.M301_1890	3.03e-27	107.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VYPK@28216|Betaproteobacteria,2KMQ0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_202439_1	555500.I215_08822	4.1e-42	144.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_202439_2	313596.RB2501_07650	7.87e-71	223.0	COG2865@1|root,COG2865@2|Bacteria,4NEF5@976|Bacteroidetes,1HYUG@117743|Flavobacteriia	976|Bacteroidetes	K	PFAM Divergent AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
k59_53260_1	1049564.TevJSym_ac00030	2.9e-23	94.4	COG2863@1|root,COG2863@2|Bacteria,1RBXV@1224|Proteobacteria,1SEAS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_53260_2	2340.JV46_05550	1.51e-79	243.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria,1JAZI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	dnr	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_46601_1	1165841.SULAR_00140	1.08e-107	317.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_195722_1	1504672.669787602	4.4e-54	186.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VIFB@28216|Betaproteobacteria,4AC3V@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular	cobS	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CobS_N
k59_19623_1	565045.NOR51B_314	1.98e-49	158.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1S83W@1236|Gammaproteobacteria,1JBIM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k59_19623_2	391615.ABSJ01000037_gene932	3.36e-82	243.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
k59_19623_3	314275.MADE_1020310	2.39e-31	111.0	COG4680@1|root,COG4680@2|Bacteria,1N036@1224|Proteobacteria,1S6VU@1236|Gammaproteobacteria,46831@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
k59_80407_1	1384066.JAGT01000001_gene158	5.17e-21	104.0	COG5184@1|root,COG5184@2|Bacteria,1TS5I@1239|Firmicutes,24A8Z@186801|Clostridia,3WRHH@541000|Ruminococcaceae	186801|Clostridia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2,SLH
k59_215799_2	1131553.JIBI01000005_gene2192	1.18e-38	142.0	COG0589@1|root,COG0589@2|Bacteria,1PE08@1224|Proteobacteria,2VNHV@28216|Betaproteobacteria,373RK@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_195725_1	243265.plu4807	8.76e-31	118.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	wblK	-	2.6.1.87	ko:K07806	ko00520,ko01503,ko02020,map00520,map01503,map02020	M00721,M00761	R07659	RC00006,RC01514	ko00000,ko00001,ko00002,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_175319_1	385682.AFSL01000012_gene2791	2.35e-50	164.0	COG2801@1|root,COG2801@2|Bacteria,4NIBY@976|Bacteroidetes	976|Bacteroidetes	L	Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_46606_1	1121468.AUBR01000044_gene1844	3.06e-12	63.9	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,42G80@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_46606_2	1165841.SULAR_07940	4.72e-71	216.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2YP4I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_53273_1	1165841.SULAR_05478	1.35e-51	166.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42R6H@68525|delta/epsilon subdivisions,2YP0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_53273_2	1165841.SULAR_05473	2.17e-61	197.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2YME5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_12588_1	395493.BegalDRAFT_0216	1.99e-26	99.8	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,460SW@72273|Thiotrichales	72273|Thiotrichales	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_175320_1	228410.NE2277	3.31e-32	120.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,372R4@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.6,5.1.3.7	ko:K02473,ko:K08679	ko00520,ko01100,map00520,map01100	-	R00418,R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_46608_1	1168034.FH5T_12385	3.1e-103	324.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,2FKZJ@200643|Bacteroidia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_141304_1	596151.DesfrDRAFT_2466	1.55e-66	214.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2M7UI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_94163_1	388467.A19Y_1423	2.38e-38	148.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_107883_1	1165841.SULAR_06303	1.52e-161	466.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_202462_1	1158146.KB907121_gene1248	1.94e-16	83.6	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	sphX	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_175330_1	387093.SUN_0633	4.81e-75	251.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_107888_1	1163617.SCD_n02422	1e-67	216.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_26239_1	167550.EV00_1408	6.24e-31	112.0	COG1694@1|root,COG1694@2|Bacteria,1G25W@1117|Cyanobacteria,1MMRE@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	MazG
k59_171575_1	1047013.AQSP01000123_gene1531	1.41e-44	165.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_158059_1	314230.DSM3645_28137	2.52e-18	81.6	COG3436@1|root,COG3436@2|Bacteria,2J11P@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_124047_1	1168034.FH5T_16780	7.3e-102	311.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_212194_1	697282.Mettu_1061	1.71e-39	149.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales	135618|Methylococcales	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
k59_198825_1	314230.DSM3645_19208	1.29e-06	48.9	COG1594@1|root,COG1594@2|Bacteria,2J03M@203682|Planctomycetes	203682|Planctomycetes	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_198825_2	314230.DSM3645_19203	7.39e-65	209.0	COG1645@1|root,COG1645@2|Bacteria	2|Bacteria	S	bacterial-type flagellum-dependent swarming motility	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	-
k59_8748_1	765912.Thimo_2947	1.75e-48	166.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1WWEJ@135613|Chromatiales	135613|Chromatiales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_171585_1	411154.GFO_2921	5.96e-71	231.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_97039_1	96561.Dole_0849	4.53e-83	268.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MIPG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_191872_1	489825.LYNGBM3L_44640	2.3e-05	52.8	COG2203@1|root,COG2268@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2268@2|Bacteria,COG5002@2|Bacteria,1G39J@1117|Cyanobacteria,1H8S2@1150|Oscillatoriales	1117|Cyanobacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,GAF
k59_124062_1	335283.Neut_1778	1.26e-07	52.4	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,372AJ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_171589_2	870187.Thini_1086	7.71e-69	211.0	COG0639@1|root,COG0639@2|Bacteria,1N2CE@1224|Proteobacteria,1S59R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
k59_15639_1	1249627.D779_1317	1.11e-60	187.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1WY87@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_15639_2	2340.JV46_23520	1.36e-122	360.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1J4QP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_191875_1	118168.MC7420_2172	2.99e-131	383.0	COG0535@1|root,COG0535@2|Bacteria,1G1TV@1117|Cyanobacteria,1HDP9@1150|Oscillatoriales	1117|Cyanobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k59_2170_1	1049564.TevJSym_ae00860	1.31e-33	121.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,1S8J5@1236|Gammaproteobacteria,1JAXC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Domain of unknown function (DUF1924)	shp	-	-	-	-	-	-	-	-	-	-	-	DUF1924
k59_49706_1	1165841.SULAR_05898	2.99e-154	465.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_83580_2	886377.Murru_0274	1.21e-55	186.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_90356_1	870187.Thini_4101	3.2e-28	118.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1MWJA@1224|Proteobacteria	1224|Proteobacteria	LO	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DUF4062,Pentapeptide,TIR_2,WD40
k59_90362_1	857087.Metme_2573	1.01e-18	85.9	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1XF7I@135618|Methylococcales	135618|Methylococcales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_49719_1	693986.MOC_0271	4.69e-69	230.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,1JR6Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_2179_1	1165841.SULAR_10139	3.82e-126	369.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2YN8R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_144286_1	2340.JV46_27570	4.45e-22	89.4	COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_144286_2	1056820.KB900643_gene813	8.7e-39	132.0	COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria,2PQD1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	K	Nitrogen regulatory protein P-II	VV0993	-	-	-	-	-	-	-	-	-	-	-	-
k59_49726_1	2340.JV46_05320	2.59e-106	322.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,1S0H0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_29287_1	1121935.AQXX01000112_gene5751	8.82e-43	152.0	COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphoesterase DHHA1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
k59_56248_1	395961.Cyan7425_1795	2.45e-38	147.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3KH7X@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_124080_2	1121875.KB907546_gene2246	1.38e-57	196.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_29289_1	631362.Thi970DRAFT_01238	1.1e-07	53.5	COG0642@1|root,COG2202@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X0I6@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_2181_1	226186.BT_0070	1.55e-31	119.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,2FNIQ@200643|Bacteroidia	976|Bacteroidetes	L	COG COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_63186_1	1120966.AUBU01000005_gene3721	1.57e-12	68.6	COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,47N77@768503|Cytophagia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
k59_22461_1	1121012.AUKX01000055_gene1628	2.4e-26	106.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia,23GIQ@178469|Arenibacter	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_178169_1	521719.ATXQ01000009_gene820	3.92e-27	108.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1YE1T@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990	Transket_pyr,Transketolase_C,Transketolase_N
k59_178169_2	1177928.TH2_09114	3.06e-16	78.6	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2TQVA@28211|Alphaproteobacteria,2JQR0@204441|Rhodospirillales	204441|Rhodospirillales	U	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_212222_1	1121405.dsmv_3115	3.71e-41	138.0	COG2331@1|root,COG2331@2|Bacteria,1NXZ2@1224|Proteobacteria,430NM@68525|delta/epsilon subdivisions,2WW4D@28221|Deltaproteobacteria,2MNK0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_212222_2	395493.BegalDRAFT_2913	6.42e-33	120.0	COG4970@1|root,COG4970@2|Bacteria,1NA3K@1224|Proteobacteria	1224|Proteobacteria	NU	General Secretion Pathway protein	gspH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
k59_130837_1	511.JT27_11810	6.89e-50	165.0	COG3195@1|root,COG3195@2|Bacteria,1RH9S@1224|Proteobacteria,2WEDX@28216|Betaproteobacteria,3T3VQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K13485	ko00230,ko01100,map00230,map01100	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
k59_8802_1	1165841.SULAR_00850	2.82e-169	489.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_144310_1	572480.Arnit_3104	3.28e-180	511.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,42MA8@68525|delta/epsilon subdivisions,2YNA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_205496_1	1165841.SULAR_06878	7.18e-13	67.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_205496_2	1165841.SULAR_06873	3.17e-60	192.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2YNGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_144314_1	1408433.JHXV01000016_gene1844	2.18e-74	238.0	COG1032@1|root,COG1032@2|Bacteria,4NH8Y@976|Bacteroidetes,1HZR8@117743|Flavobacteriia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_171611_1	760568.Desku_1546	2.54e-28	117.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,260IK@186807|Peptococcaceae	186801|Clostridia	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_191946_1	765912.Thimo_0624	1.1e-32	131.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WVYT@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg
k59_198882_1	935557.ATYB01000008_gene4833	4.49e-21	103.0	COG2267@1|root,COG2303@1|root,COG3540@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,COG3540@2|Bacteria,1QQ8F@1224|Proteobacteria,2U7D4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EI	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_124114_1	545264.KB898754_gene1820	2.41e-90	277.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_2618_1	313596.RB2501_07660	3.76e-96	287.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,1HYAW@117743|Flavobacteriia	976|Bacteroidetes	G	Sugar kinases, ribokinase family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_16088_1	1168034.FH5T_06385	1.57e-116	346.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_36254_1	1165841.SULAR_06983	1.51e-39	135.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2YT8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_36254_2	1165841.SULAR_06978	2.74e-72	220.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2YP7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_178551_1	246195.DNO_0456	2.34e-11	71.6	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K10823,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_70156_1	1165841.SULAR_01035	1.31e-76	251.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	2|Bacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_9274_1	913325.N799_02630	1.29e-11	68.2	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1X3C8@135614|Xanthomonadales	135614|Xanthomonadales	M	tonb protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_36263_1	1165841.SULAR_09179	2.49e-21	92.8	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07648,ko:K07679	ko02020,ko02026,ko05133,map02020,map02026,map05133	M00456,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF_2,HATPase_c,HisKA,Hpt,PAS,Response_reg
k59_36263_2	387093.SUN_0449	2.25e-69	220.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YPKY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_178557_1	1165841.SULAR_00365	6.56e-125	365.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_120936_1	997884.HMPREF1068_02031	1.16e-74	241.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,2FNDJ@200643|Bacteroidia,4AKX4@815|Bacteroidaceae	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_181599_1	1168034.FH5T_12070	3.37e-98	295.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,2FWV2@200643|Bacteroidia	976|Bacteroidetes	E	Putative serine dehydratase domain	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
k59_113476_1	1121859.KB890757_gene1742	0.000248	48.5	COG0018@1|root,COG0018@2|Bacteria	2|Bacteria	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_80056_1	1249627.D779_0942	3.13e-77	252.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales	135613|Chromatiales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_168269_3	1137281.D778_01529	1.36e-15	72.0	COG3609@1|root,COG3609@2|Bacteria,4NTDN@976|Bacteroidetes,1I3XS@117743|Flavobacteriia	976|Bacteroidetes	K	addiction module antidote protein, CC2985 family	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
k59_66734_1	1249627.D779_1738	3.77e-202	567.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1WWEJ@135613|Chromatiales	135613|Chromatiales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_25788_1	870187.Thini_2789	3.06e-53	179.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_100483_1	1249627.D779_0958	1.1e-68	231.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,1RPDC@1236|Gammaproteobacteria,1WWR8@135613|Chromatiales	135613|Chromatiales	S	PFAM Bacterial domain of	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_168277_1	404380.Gbem_3278	2.37e-12	71.6	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_113490_1	1165841.SULAR_03093	1.12e-78	242.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2YMA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_181608_1	240015.ACP_1196	1.08e-198	564.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_202142_1	472759.Nhal_1091	4.85e-62	192.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1WYAE@135613|Chromatiales	135613|Chromatiales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_202142_2	1207076.ALAT01000221_gene3511	1.53e-09	63.5	COG3071@1|root,COG3071@2|Bacteria,1N8NX@1224|Proteobacteria,1SACE@1236|Gammaproteobacteria,1Z0AG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
k59_148102_1	313596.RB2501_05265	7.52e-105	316.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1HXKA@117743|Flavobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_32744_1	1168034.FH5T_11220	1.76e-21	97.1	COG0845@1|root,COG0845@2|Bacteria,4NIJI@976|Bacteroidetes,2FNGW@200643|Bacteroidia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
k59_215402_1	435591.BDI_3285	8.28e-08	53.1	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_215402_2	485918.Cpin_5561	1.8e-10	68.6	COG3193@1|root,COG3193@2|Bacteria,4NGTI@976|Bacteroidetes,1IPED@117747|Sphingobacteriia	976|Bacteroidetes	S	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_100487_1	1168034.FH5T_08165	9.85e-74	229.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,2FMAG@200643|Bacteroidia	976|Bacteroidetes	C	aldo keto reductase family	gpr	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
k59_52942_2	314345.SPV1_00987	2.56e-09	53.9	2DPGY@1|root,3320R@2|Bacteria,1ND7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
k59_168282_1	387093.SUN_1766	3.39e-78	240.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_154619_1	450851.PHZ_c1972	1.39e-20	87.8	COG0625@1|root,COG0625@2|Bacteria,1PENB@1224|Proteobacteria,2TRVC@28211|Alphaproteobacteria,2KGKW@204458|Caulobacterales	204458|Caulobacterales	O	PFAM Glutathione S-transferase domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
k59_154619_2	314230.DSM3645_20927	4.18e-16	80.1	COG2242@1|root,COG2242@2|Bacteria,2J0UY@203682|Planctomycetes	203682|Planctomycetes	H	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_195444_1	1033736.CAHK01000037_gene2524	6.99e-21	97.1	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4F9J8@85019|Brevibacteriaceae	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_195444_2	7425.NV16073-PA	1.21e-06	58.5	COG0554@1|root,KOG2517@2759|Eukaryota,39JP3@33154|Opisthokonta,3BAII@33208|Metazoa,3CTYP@33213|Bilateria,41URK@6656|Arthropoda,3SGMA@50557|Insecta,46E63@7399|Hymenoptera	33208|Metazoa	G	FGGY family of carbohydrate kinases, C-terminal domain	GK5	GO:0003674,GO:0003824,GO:0004370,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006066,GO:0006071,GO:0006072,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046167,GO:0046486,GO:0052646,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576,GO:1901615	2.7.1.30	ko:K19583	-	-	-	-	ko00000,ko01000	-	-	-	FGGY_C,FGGY_N
k59_5903_1	2340.JV46_26910	9.09e-15	80.5	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1JC0F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_113504_1	1134474.O59_003725	4.33e-43	150.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1FFTZ@10|Cellvibrio	1236|Gammaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_0056	PdxA
k59_113504_2	2340.JV46_11630	1.45e-74	224.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1J6BH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_113504_3	2340.JV46_11620	1.23e-162	466.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1J4JZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_154623_1	690850.Desaf_0758	4.75e-46	157.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2MA46@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	pfam abc	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_168291_2	391595.RLO149_c037010	4.71e-68	221.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	MA20_04810	-	3.5.1.82	ko:K01461	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_3
k59_141017_1	1283300.ATXB01000001_gene1637	7.31e-74	228.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1XE78@135618|Methylococcales	135618|Methylococcales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_202158_1	2340.JV46_10150	2.11e-74	226.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_202158_2	1280001.BAOA01000077_gene3114	1.37e-43	154.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1XT6K@135623|Vibrionales	135623|Vibrionales	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_59964_1	1280666.ATVS01000043_gene1585	1.32e-22	101.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,4BW05@830|Butyrivibrio	186801|Clostridia	P	E1-E2 ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
k59_86937_1	1165841.SULAR_07400	6.08e-71	218.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SSI@68525|delta/epsilon subdivisions,2YPDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_86937_2	1165841.SULAR_07395	4.14e-10	59.7	COG0642@1|root,COG2205@2|Bacteria,1R5ZF@1224|Proteobacteria,43CBR@68525|delta/epsilon subdivisions,2YTBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_195451_1	1168034.FH5T_19565	1.02e-76	236.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,2G0DY@200643|Bacteroidia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_100506_1	326297.Sama_3480	3.8e-07	57.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,2QAFZ@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the GPAT DAPAT family	plsB	GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iECs_1301.ECs5024,iG2583_1286.G2583_4866	Acyltransferase
k59_208960_1	1454004.AW11_01915	4.42e-28	117.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria	1224|Proteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_66761_2	316067.Geob_0866	6.77e-46	164.0	COG2010@1|root,COG5557@1|root,COG2010@2|Bacteria,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
k59_73437_1	313603.FB2170_05505	2.03e-17	80.1	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1HY3S@117743|Flavobacteriia,2PGNK@252356|Maribacter	976|Bacteroidetes	L	recA bacterial DNA recombination protein	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_73437_2	886377.Murru_1428	2.85e-57	186.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
k59_168667_1	3702.ATMG01275.1	3.58e-76	235.0	COG1005@1|root,KOG4770@2759|Eukaryota,37V23@33090|Viridiplantae,3GIN5@35493|Streptophyta,3I0WR@3699|Brassicales	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)	nad1	GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114	1.6.5.3	ko:K03878	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_60296_1	760192.Halhy_3559	2.39e-10	66.6	COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,1IWFX@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_154990_2	2340.JV46_28500	7.64e-157	449.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1J5B3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_53296_2	1392490.JHZX01000001_gene543	1.68e-05	48.9	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,1I0Q1@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_87252_1	1168034.FH5T_07980	2.96e-57	181.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_87252_2	1168289.AJKI01000002_gene2554	1.73e-10	61.6	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes,2FVZZ@200643|Bacteroidia,3XKEM@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_168671_1	526222.Desal_1909	2.86e-39	143.0	COG3409@1|root,COG3409@2|Bacteria,1RAFU@1224|Proteobacteria,436N6@68525|delta/epsilon subdivisions,2X9K4@28221|Deltaproteobacteria,2MEJV@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_19644_1	1123355.JHYO01000013_gene1150	2.1e-59	196.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,36X6V@31993|Methylocystaceae	28211|Alphaproteobacteria	F	IMP dehydrogenase / GMP reductase domain	-	-	-	-	-	-	-	-	-	-	-	-	IMPDH
k59_67111_1	1121011.AUCB01000056_gene4039	1.43e-88	276.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,23HR7@178469|Arenibacter	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_6161_1	1283300.ATXB01000001_gene2341	3.82e-124	357.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_6161_2	1123278.KB893618_gene3433	2.94e-11	61.2	COG3335@1|root,COG3335@2|Bacteria,4PNWI@976|Bacteroidetes	976|Bacteroidetes	L	SPTR Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_12618_1	765911.Thivi_0437	1.41e-58	194.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RN50@1236|Gammaproteobacteria,1WXR5@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM release factor H-coupled RctB family protein	-	-	-	ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001	-	-	-	RtcB
k59_12624_1	305700.B447_21127	6.94e-17	82.4	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2VHK0@28216|Betaproteobacteria,2KUE4@206389|Rhodocyclales	206389|Rhodocyclales	G	Malonyl-CoA decarboxylase N-terminal domain	-	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
k59_155004_1	745411.B3C1_05892	5.02e-19	91.3	COG4932@1|root,COG4932@2|Bacteria,1R944@1224|Proteobacteria,1S165@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53313_1	796620.VIBC2010_07284	2.24e-50	179.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XUER@135623|Vibrionales	135623|Vibrionales	M	COG0668 Small-conductance mechanosensitive channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_84132_1	313603.FB2170_09331	2.44e-104	313.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia,2PG6N@252356|Maribacter	976|Bacteroidetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_124682_1	1564096.A0A0A0YRA5_9CAUD	1.39e-55	193.0	4QHDM@10239|Viruses,4QRD0@28883|Caudovirales,4QI2W@10662|Myoviridae	10662|Myoviridae	S	Terminase-like family	-	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949	-	-	-	-	-	-	-	-	-	-	-
k59_199436_1	340.xcc-b100_1812	4.71e-61	219.0	COG0784@1|root,COG2198@1|root,COG3290@1|root,COG3614@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3290@2|Bacteria,COG3614@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1X3VB@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_151805_1	1284708.HMPREF1634_03340	2.87e-18	89.4	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WCF4@538999|Clostridiales incertae sedis	186801|Clostridia	L	Helix-hairpin-helix motif	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_84133_1	1165841.SULAR_00800	8.06e-62	204.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YTMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	COG4232 Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbD,Thioredoxin_2
k59_84133_2	1165841.SULAR_00790	1.88e-47	160.0	COG2267@1|root,COG2267@2|Bacteria,1REM6@1224|Proteobacteria,42VM4@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Serine aminopeptidase, S33	lip	-	3.7.1.13	ko:K15756	ko00621,ko01100,ko01120,ko01220,map00621,map01100,map01120,map01220	M00544	R05365	RC00753,RC00757	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
k59_118106_1	903818.KI912268_gene1710	3.45e-128	372.0	COG3943@1|root,COG3943@2|Bacteria	2|Bacteria	-	-	rhuM	-	-	ko:K14623	-	-	-	-	ko00000,ko03400	-	-	-	Virulence_RhuM
k59_199442_1	314285.KT71_01085	2.11e-44	144.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1J6B1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_199442_2	857087.Metme_3813	2.51e-80	244.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1XDYR@135618|Methylococcales	135618|Methylococcales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_104419_1	1122604.JONR01000022_gene680	9.99e-34	129.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1X5SG@135614|Xanthomonadales	135614|Xanthomonadales	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_56870_1	1278309.KB907101_gene782	1.55e-22	94.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1XJCZ@135619|Oceanospirillales	135619|Oceanospirillales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_56870_2	686340.Metal_1613	1.66e-24	102.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1XDVJ@135618|Methylococcales	135618|Methylococcales	L	DNA polymerase III, delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k59_172154_1	1165841.SULAR_00870	3.98e-06	48.9	COG3218@1|root,COG3218@2|Bacteria,1NNSH@1224|Proteobacteria,42X3M@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	transport system auxiliary component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
k59_212786_1	5518.FGSG_02893P0	2.24e-09	64.3	2CH50@1|root,2QVJA@2759|Eukaryota,38I5H@33154|Opisthokonta,3NUEA@4751|Fungi,3QRRK@4890|Ascomycota,213UC@147550|Sordariomycetes,3TGEZ@5125|Hypocreales,1FQIW@110618|Nectriaceae	4751|Fungi	S	Protein-arginine deiminase (PAD)	-	-	3.5.3.15	ko:K01481	-	-	-	-	ko00000,ko01000	-	-	-	PAD
k59_2848_1	10224.XP_002739487.1	1.72e-57	200.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3BPSU@33208|Metazoa,3E41R@33213|Bilateria	33208|Metazoa	IQ	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_131487_1	1165841.SULAR_00125	3.99e-130	370.0	COG3439@1|root,COG3439@2|Bacteria,1REDZ@1224|Proteobacteria,42T1V@68525|delta/epsilon subdivisions,2YPRR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_111095_1	335543.Sfum_2600	7.9e-94	288.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_77292_1	648757.Rvan_0984	1.78e-86	281.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2TR2N@28211|Alphaproteobacteria,3N80D@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_124701_1	313596.RB2501_01835	3.77e-101	311.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia	976|Bacteroidetes	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_22988_1	314285.KT71_14689	1.72e-37	142.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1J531@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	M COG4775 Outer membrane protein protective antigen OMA87	ytfM	GO:0002790,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
k59_29943_1	1121405.dsmv_1068	2.03e-102	303.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,42NK5@68525|delta/epsilon subdivisions,2WJ49@28221|Deltaproteobacteria,2MJA7@213118|Desulfobacterales	28221|Deltaproteobacteria	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
k59_63762_1	758.BBIX01000009_gene2148	8.26e-27	107.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1Y84C@135625|Pasteurellales	135625|Pasteurellales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_63762_2	998674.ATTE01000001_gene1731	9.9e-48	158.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,460T1@72273|Thiotrichales	72273|Thiotrichales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_63762_3	90814.KL370891_gene1669	1.43e-27	103.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,460Q7@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_9532_2	521674.Plim_2914	1.5e-37	139.0	COG3616@1|root,COG3616@2|Bacteria,2IYAY@203682|Planctomycetes	203682|Planctomycetes	E	amino acid aldolase or racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
k59_192517_1	1454004.AW11_00313	1.85e-13	72.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,1KQRQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	peptidylprolyl isomerase	cbf2	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N_3
k59_29949_1	1168034.FH5T_04985	1.1e-63	197.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,2FS3I@200643|Bacteroidia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_29949_2	1408473.JHXO01000001_gene1953	2.16e-30	110.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_172167_1	1548151.LS70_09600	2.94e-24	93.6	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria	1224|Proteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_172167_2	1443125.Z962_00170	1.53e-43	149.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,36EGR@31979|Clostridiaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_145028_1	13249.RPRC009321-PA	2.59e-18	85.5	COG0438@1|root,KOG1111@2759|Eukaryota	2759|Eukaryota	M	phosphatidylinositol N-acetylglucosaminyltransferase activity	-	-	2.4.1.198	ko:K03857	ko00563,ko01100,map00563,map01100	M00065	R05916	-	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_145028_2	472759.Nhal_1448	2.75e-28	112.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1WZA1@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
k59_63766_1	1165841.SULAR_02803	1.24e-111	323.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_16303_1	1027273.GZ77_22465	2.5e-35	129.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,1XRJW@135619|Oceanospirillales	135619|Oceanospirillales	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_172173_1	1183438.GKIL_1817	2.08e-47	173.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Formyl_trans_N,Methyltransf_12,PP-binding,PilZ
k59_145034_1	675806.VII_001893	1.45e-13	69.7	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RR72@1236|Gammaproteobacteria,1XT5H@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, periplasmic component	dctP	GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015740,GO:0015849,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_97862_1	1173022.Cri9333_4331	5.44e-27	116.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,Pkinase,Response_reg
k59_9543_1	1121033.AUCF01000013_gene1632	1.07e-16	84.3	COG0642@1|root,COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,2JR29@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,dCache_1
k59_29963_1	1168034.FH5T_05235	3.64e-109	331.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,2G0E2@200643|Bacteroidia	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_165240_1	478741.JAFS01000002_gene87	3.39e-78	244.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_178752_1	1236542.BALM01000033_gene2103	1.06e-10	61.2	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,2QA3V@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein, LysR	IV02_27905	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_118142_1	1165841.SULAR_07480	4.81e-14	70.9	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_118142_2	1165841.SULAR_07475	2.62e-94	279.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2YNW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_36420_1	1121937.AUHJ01000036_gene2807	1.53e-219	610.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,4640P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_57251_1	1165841.SULAR_05508	6.66e-127	379.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_23401_1	883.DvMF_2994	2.76e-08	56.2	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2M7ZM@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_23401_2	693746.OBV_07210	2.43e-19	86.3	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,2N6HA@216572|Oscillospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_179016_1	1397528.Q671_11105	1.19e-43	156.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XHJ5@135619|Oceanospirillales	135619|Oceanospirillales	O	protease	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_165652_1	768671.ThimaDRAFT_1257	6.15e-15	72.4	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,1S0X4@1236|Gammaproteobacteria,1WW14@135613|Chromatiales	135613|Chromatiales	S	PFAM Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
k59_165652_2	1249627.D779_1706	3.85e-20	84.0	2E4UR@1|root,32ZP4@2|Bacteria,1N83W@1224|Proteobacteria,1SEK3@1236|Gammaproteobacteria,1WZ72@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_172587_1	2340.JV46_18810	1.33e-100	302.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1J4WF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_98206_1	545276.KB898729_gene1653	1.27e-20	88.2	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1WVYQ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_213224_1	629265.PMA4326_29130	7.77e-05	44.3	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1Z5G6@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	I	Malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
k59_213224_2	519989.ECTPHS_10361	6.9e-121	353.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1WWWT@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_213227_1	1165841.SULAR_05193	1.36e-88	283.0	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_104850_1	4558.Sb06g013680.1	8.48e-86	286.0	COG2801@1|root,KOG0017@2759|Eukaryota,38A58@33090|Viridiplantae,3GXPE@35493|Streptophyta,3MB5P@4447|Liliopsida,3IUQY@38820|Poales	35493|Streptophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVP,RVT_1,zf-CCHC
k59_43575_1	1168034.FH5T_10865	3.75e-85	268.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,2FMMD@200643|Bacteroidia	976|Bacteroidetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_118603_1	1165841.SULAR_06733	5.46e-90	278.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_131907_1	3649.evm.model.supercontig_263.4	5e-167	481.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,3GEEJ@35493|Streptophyta,3HWMV@3699|Brassicales	35493|Streptophyta	C	Cytochrome C and Quinol oxidase polypeptide I	cox1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k59_30418_1	631362.Thi970DRAFT_03279	3.15e-41	154.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1WXT3@135613|Chromatiales	135613|Chromatiales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_36770_1	1168034.FH5T_14400	2.52e-135	392.0	COG4213@1|root,COG4213@2|Bacteria,4NNBW@976|Bacteroidetes,2FWT8@200643|Bacteroidia	976|Bacteroidetes	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
k59_43580_1	350688.Clos_0512	2.73e-36	137.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,36F8Y@31979|Clostridiaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_165677_1	388413.ALPR1_02210	1.17e-33	134.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_70827_1	765914.ThisiDRAFT_1856	2.69e-97	298.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,HSDR_N_2
k59_199846_1	269797.Mbar_A1663	2.69e-124	366.0	COG1228@1|root,arCOG00696@2157|Archaea,2XWAY@28890|Euryarchaeota	28890|Euryarchaeota	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_111535_1	1165841.SULAR_09749	3.78e-16	76.6	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_111535_2	1165841.SULAR_09754	1.66e-72	223.0	COG3751@1|root,COG3751@2|Bacteria,1Q4MK@1224|Proteobacteria,42ZFP@68525|delta/epsilon subdivisions,2YRNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_145529_1	1387197.AWGA01000059_gene328	6.07e-50	164.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_114153_1	1027273.GZ77_13200	1.96e-61	199.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1XH44@135619|Oceanospirillales	135619|Oceanospirillales	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_169061_1	1453501.JELR01000002_gene601	1.06e-33	122.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,465E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_39709_1	313596.RB2501_05360	3.66e-47	168.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_12969_1	933262.AXAM01000009_gene1481	5.75e-48	163.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria,2MHKP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12969_2	880072.Desac_1419	5.54e-20	87.8	COG0398@1|root,COG0398@2|Bacteria,1QKZU@1224|Proteobacteria,42SRQ@68525|delta/epsilon subdivisions,2WP35@28221|Deltaproteobacteria,2MQG7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_169062_1	945713.IALB_1488	1.01e-22	102.0	COG3291@1|root,COG4409@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4409@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	wcoB	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix,PKD,Reprolysin_4
k59_33414_1	313596.RB2501_12652	5.27e-31	114.0	2DI3V@1|root,32UAD@2|Bacteria,4NUQE@976|Bacteroidetes,1I2BK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33414_2	313596.RB2501_12647	4.43e-15	71.2	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I1Y2@117743|Flavobacteriia	976|Bacteroidetes	O	Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_162083_1	1165841.SULAR_05613	1.1e-65	208.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2YMBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_33415_2	395493.BegalDRAFT_2615	7.34e-41	136.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,4613R@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_33415_3	395493.BegalDRAFT_2616	1.9e-19	80.9	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,461CG@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_114172_1	1174504.AJTN02000018_gene1891	3.78e-12	72.0	COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus	91061|Bacilli	V	Multidrug efflux pump	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_33416_1	1173028.ANKO01000042_gene815	2.53e-120	352.0	COG4122@1|root,COG4122@2|Bacteria,1G0IH@1117|Cyanobacteria,1H9HU@1150|Oscillatoriales	1117|Cyanobacteria	S	O-methyltransferase family 3	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
k59_169075_1	1410608.JNKX01000063_gene2599	4.62e-07	57.0	COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,2FWGT@200643|Bacteroidia,4AV2U@815|Bacteroidaceae	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
k59_6513_2	439235.Dalk_1463	4.9e-41	145.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_188790_1	1168034.FH5T_05520	1.03e-116	337.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,2FMV3@200643|Bacteroidia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_46976_1	572547.Amico_1732	1.78e-10	60.5	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	wbbJ	-	2.3.1.209	ko:K21379	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
k59_46976_2	395493.BegalDRAFT_3469	5.38e-25	103.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87,TPR_2,TPR_8
k59_148732_2	1226322.HMPREF1545_04309	1.96e-21	95.1	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,2N6XH@216572|Oscillospiraceae	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_121574_1	314275.MADE_1014590	4.02e-31	117.0	2CABR@1|root,32TG1@2|Bacteria,1N041@1224|Proteobacteria,1S4Q8@1236|Gammaproteobacteria,46BGC@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_121574_2	1288494.EBAPG3_19100	2.8e-09	62.0	2DT4R@1|root,33IPZ@2|Bacteria,1NIT6@1224|Proteobacteria,2VYMT@28216|Betaproteobacteria,37341@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148735_1	1168034.FH5T_05070	3.37e-109	318.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,2FMCD@200643|Bacteroidia	976|Bacteroidetes	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_175812_1	264402.Cagra.0259s0008.1.p	7.69e-29	113.0	COG0356@1|root,KOG4665@2759|Eukaryota,37J5M@33090|Viridiplantae,3GEF0@35493|Streptophyta	35493|Streptophyta	C	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel	atp6-1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	ko:K02126	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko03029	3.A.2.1	-	-	ATP-synt_A
k59_53646_1	1499967.BAYZ01000117_gene3319	1.26e-70	222.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	licA	-	2.7.1.89	ko:K07251	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	APH,Choline_kinase
k59_148740_1	187272.Mlg_1360	1.78e-33	127.0	COG1985@1|root,COG1985@2|Bacteria,1RDMT@1224|Proteobacteria,1S4SQ@1236|Gammaproteobacteria,1X05Z@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
k59_40152_1	1342302.JASC01000014_gene2360	4.48e-21	92.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3ZVWX@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k59_40152_2	1342302.JASC01000014_gene2361	4.14e-19	84.3	2DMHK@1|root,32RM5@2|Bacteria,1N1AD@1224|Proteobacteria,2UW0B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
k59_13485_2	2340.JV46_03640	2.37e-66	215.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1J8NJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	mltB	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031402,GO:0031420,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044462,GO:0044464,GO:0046872,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	iECABU_c1320.ECABU_c29710,iNRG857_1313.NRG857_13215	SLT_2
k59_73990_1	1469245.JFBG01000040_gene1721	1.18e-68	223.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1WWC9@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_210023_1	378806.STAUR_6946	1.73e-13	72.4	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria	1224|Proteobacteria	IQ	COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_210023_2	1007103.AFHW01000129_gene6280	3.21e-18	85.5	COG3321@1|root,COG3321@2|Bacteria,1VUA3@1239|Firmicutes,4HURX@91061|Bacilli,271AV@186822|Paenibacillaceae	91061|Bacilli	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
k59_26969_2	395493.BegalDRAFT_3265	2.02e-82	256.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,45ZZH@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_176124_1	1403819.BATR01000123_gene4353	1.64e-16	77.4	2E4Z6@1|root,32FHE@2|Bacteria,46WG6@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40161_1	686340.Metal_3947	1.39e-68	218.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XDKU@135618|Methylococcales	135618|Methylococcales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_26972_1	1165841.SULAR_01678	3.57e-111	330.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_73992_1	395493.BegalDRAFT_1884	1.26e-108	340.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,45ZUB@72273|Thiotrichales	72273|Thiotrichales	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_135537_2	1307437.J139_00440	3.11e-44	154.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,2Q1HY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_26973_1	402881.Plav_0185	3.14e-26	112.0	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,2TR9M@28211|Alphaproteobacteria,1JNN9@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_203278_1	156578.ATW7_12196	2.32e-05	47.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_203278_2	69014.TK1334	3.4e-05	48.9	COG0237@1|root,arCOG01045@2157|Archaea,2XWNJ@28890|Euryarchaeota,2433T@183968|Thermococci	183968|Thermococci	H	Belongs to the UPF0200 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17
k59_142153_2	1122179.KB890446_gene399	5.32e-16	76.3	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,1ISQ6@117747|Sphingobacteriia	976|Bacteroidetes	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_162491_1	1121937.AUHJ01000001_gene773	1.11e-68	219.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,4650N@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2485	M20_dimer,Peptidase_M20
k59_101562_1	28072.Nos7524_1951	6.84e-06	53.5	COG0697@1|root,COG0697@2|Bacteria,1G23N@1117|Cyanobacteria,1HKD2@1161|Nostocales	1117|Cyanobacteria	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_128526_1	1441930.Z042_06045	1.37e-20	89.0	2E72W@1|root,331MG@2|Bacteria,1NAVS@1224|Proteobacteria,1SGAE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26978_1	543728.Vapar_2357	1.13e-68	231.0	COG2885@1|root,COG3808@1|root,COG2885@2|Bacteria,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,4AA75@80864|Comamonadaceae	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_210041_1	398767.Glov_2182	1.06e-31	128.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,43UFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_155712_1	453591.Igni_0512	4.65e-13	74.3	COG0373@1|root,arCOG01036@2157|Archaea,2XQHB@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_142164_1	378806.STAUR_4846	9.39e-39	147.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WNBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K13611	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_81279_1	631362.Thi970DRAFT_04601	4.33e-76	254.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWSZ@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_203288_1	1168034.FH5T_04005	1.35e-120	353.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_189349_1	1165841.SULAR_01858	2.19e-111	332.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_74005_1	666685.R2APBS1_0504	4.68e-27	118.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,1RYUN@1236|Gammaproteobacteria,1X3FR@135614|Xanthomonadales	135614|Xanthomonadales	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_114538_1	2340.JV46_15350	2.23e-94	289.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RZVF@1236|Gammaproteobacteria,1JBWE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	NlpB/DapX lipoprotein	bamC	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_20288_1	580332.Slit_2150	2.25e-50	171.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33853_3	1123487.KB892865_gene1391	2.19e-13	71.6	COG0553@1|root,COG0553@2|Bacteria,1PN7I@1224|Proteobacteria,2VP2N@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	SNF2_N
k59_142172_1	1249627.D779_0555	2.3e-121	358.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1WW57@135613|Chromatiales	135613|Chromatiales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_101580_1	598659.NAMH_0970	1.65e-40	149.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_101580_2	1150621.SMUL_2631	4.53e-18	80.5	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2YP44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_203294_1	639282.DEFDS_1425	1.32e-06	53.5	COG1573@1|root,COG1573@2|Bacteria,2GFD7@200930|Deferribacteres	200930|Deferribacteres	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_176144_1	449447.MAE_22460	1.43e-79	246.0	COG4589@1|root,COG4589@2|Bacteria,1GCQF@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_176144_2	449447.MAE_22450	1.83e-20	87.0	COG0204@1|root,COG0204@2|Bacteria,1GCSE@1117|Cyanobacteria	1117|Cyanobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_155723_1	398720.MED217_03375	4.58e-13	68.2	COG1577@1|root,COG1577@2|Bacteria,4NEXC@976|Bacteroidetes,1HY6C@117743|Flavobacteriia,2XIBA@283735|Leeuwenhoekiella	976|Bacteroidetes	I	GHMP Kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_155723_2	313596.RB2501_08850	1.67e-93	294.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_33857_1	469383.Cwoe_2947	7.72e-16	81.3	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CSSZ@84995|Rubrobacteria	84995|Rubrobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_189355_1	765910.MARPU_10625	1.23e-30	122.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_189355_2	2340.JV46_03040	6.7e-31	116.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1J53F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_203298_1	4155.Migut.D01329.1.p	1.44e-79	236.0	COG0197@1|root,KOG3422@2759|Eukaryota,37UTS@33090|Viridiplantae,3GIPW@35493|Streptophyta,44T4M@71274|asterids	35493|Streptophyta	J	Belongs to the universal ribosomal protein uL16 family	rpl16	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_203298_2	3880.AES67158	3.43e-19	82.8	COG0093@1|root,COG0100@1|root,KOG0408@2759|Eukaryota,KOG0901@2759|Eukaryota,37UWF@33090|Viridiplantae,3GIPC@35493|Streptophyta	35493|Streptophyta	J	Belongs to the universal ribosomal protein uL14 family	rpl14	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0008150,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0015934,GO:0019843,GO:0031974,GO:0031976,GO:0031984,GO:0032991,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0070013,GO:0070180,GO:0097159,GO:0098798,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_7287_1	948106.AWZT01000011_gene2022	1.01e-36	139.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,1K0XC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k59_7287_2	1122194.AUHU01000003_gene2392	7.43e-06	47.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,464DH@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_88700_1	83406.HDN1F_37640	9.72e-42	148.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1J4FR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein containing LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_88700_2	1124983.PFLCHA0_c00230	1.56e-26	103.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1YMFU@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_47964_1	1168034.FH5T_13835	4.17e-106	312.0	2B0HH@1|root,31SV0@2|Bacteria,4NRU4@976|Bacteroidetes,2FTFR@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_47964_2	1168034.FH5T_13830	2.41e-33	128.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
k59_102271_2	234831.PSM_A0616	3.37e-24	94.4	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,2Q2ZD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_47966_1	1127673.GLIP_2700	5.17e-76	254.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_142885_1	768671.ThimaDRAFT_4355	3.34e-144	427.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,1SKFJ@1236|Gammaproteobacteria,1X099@135613|Chromatiales	135613|Chromatiales	L	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_34473_1	167539.Pro_0482	1.21e-05	50.4	COG0001@1|root,COG0001@2|Bacteria,1G162@1117|Cyanobacteria,1MKZS@1212|Prochloraceae	1117|Cyanobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_34473_2	1408444.JHYC01000013_gene2433	1.48e-24	100.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1JD3S@118969|Legionellales	118969|Legionellales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_183515_1	926569.ANT_08030	2.29e-05	52.8	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
k59_95432_2	204669.Acid345_4675	7.63e-103	334.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_156509_1	1151116.Q7S_10915	7.4e-18	85.9	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,1RMI9@1236|Gammaproteobacteria,3FH79@34037|Rahnella	1236|Gammaproteobacteria	F	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_156509_2	1379270.AUXF01000005_gene659	6.1e-05	48.1	COG3599@1|root,COG3599@2|Bacteria,1ZUSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	DivIVA protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
k59_27724_1	1165841.SULAR_01015	1.17e-09	55.8	COG2346@1|root,COG2346@2|Bacteria,1MZSM@1224|Proteobacteria,42S0I@68525|delta/epsilon subdivisions,2YPBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG2346, Truncated hemoglobins	ctb	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_27724_2	1165841.SULAR_01025	2.17e-14	73.9	COG1413@1|root,COG1413@2|Bacteria,1NMDT@1224|Proteobacteria,42WYR@68525|delta/epsilon subdivisions,2YQSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102281_2	1173024.KI912148_gene4110	5.42e-06	50.1	COG0637@1|root,COG0637@2|Bacteria,1G50Q@1117|Cyanobacteria,1JI0X@1189|Stigonemataceae	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_176782_1	2340.JV46_19760	7.92e-70	229.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1J5D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KL	HELICc2	yoaA	GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k59_176782_2	1385515.N791_00720	2.43e-09	56.6	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1X633@135614|Xanthomonadales	135614|Xanthomonadales	O	glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k59_136110_1	41431.PCC8801_3952	4.3e-118	350.0	COG5659@1|root,COG5659@2|Bacteria,1G31J@1117|Cyanobacteria,3KJS7@43988|Cyanothece	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_75107_1	998674.ATTE01000001_gene1826	1.58e-24	104.0	COG2133@1|root,COG2133@2|Bacteria,1PH2B@1224|Proteobacteria,1S7M3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
k59_7303_1	880073.Calab_1614	2.94e-75	246.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_41233_1	1485543.JMME01000002_gene1801	1.43e-73	243.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4H6P6@909932|Negativicutes	909932|Negativicutes	V	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_102282_1	880071.Fleli_3454	3e-53	191.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,47KK6@768503|Cytophagia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_27727_1	1282876.BAOK01000002_gene486	3.46e-19	86.7	2BR25@1|root,32JZX@2|Bacteria,1NBAX@1224|Proteobacteria,2TTE5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GST_C
k59_169983_1	1248232.BANQ01000059_gene2084	2.4e-72	231.0	COG0688@1|root,COG0688@2|Bacteria,1NEF8@1224|Proteobacteria,1S006@1236|Gammaproteobacteria,1XWSQ@135623|Vibrionales	135623|Vibrionales	I	Phophatidylserine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	PSDC,PS_Dcarbxylase
k59_129285_1	317025.Tcr_0271	3.37e-18	84.3	COG0457@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,460F8@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
k59_129285_2	717773.Thicy_1517	1.82e-21	90.1	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,462W0@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129290_1	686340.Metal_0529	9.91e-46	167.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,1XDIX@135618|Methylococcales	135618|Methylococcales	E	PFAM Bacterial extracellular solute-binding	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_149668_1	1165841.SULAR_01838	7.38e-65	206.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2YM84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k59_163239_2	1540257.JQMW01000011_gene2545	2.63e-20	95.9	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,36DDY@31979|Clostridiaceae	186801|Clostridia	O	peptidylprolyl isomerase	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
k59_156518_1	218851.Aquca_023_00102.1	2.2e-27	108.0	COG2801@1|root,KOG0017@2759|Eukaryota,37TAQ@33090|Viridiplantae,3GDDG@35493|Streptophyta	35493|Streptophyta	L	cellular component organization	-	-	-	-	-	-	-	-	-	-	-	-	CcmF_C
k59_61606_1	1168065.DOK_19160	3.66e-67	215.0	COG3547@1|root,COG3547@2|Bacteria,1RBIF@1224|Proteobacteria,1SDAR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_129307_1	754477.Q7C_1824	1.65e-88	270.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,460AY@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_102285_1	1278309.KB907099_gene2912	2.02e-76	242.0	COG2132@1|root,COG2132@2|Bacteria,1R89G@1224|Proteobacteria,1S5X0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
k59_47972_1	1128427.KB904821_gene284	2.15e-40	142.0	COG2062@1|root,COG2062@2|Bacteria,1GQII@1117|Cyanobacteria,1HBTB@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k59_14176_1	1121406.JAEX01000002_gene890	1.04e-61	200.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,2MAK6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_163248_1	504472.Slin_5532	3.68e-23	93.6	COG4634@1|root,COG4634@2|Bacteria,4NYP1@976|Bacteroidetes,47WBN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_163248_2	1237149.C900_04828	2.6e-19	80.9	COG2442@1|root,COG2442@2|Bacteria,4NVK1@976|Bacteroidetes,47SGW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
k59_149681_1	1168034.FH5T_13085	7.89e-149	424.0	COG1216@1|root,COG1216@2|Bacteria,4PPEY@976|Bacteroidetes,2G18V@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_115824_1	1234364.AMSF01000001_gene2365	1.64e-19	93.6	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1X503@135614|Xanthomonadales	135614|Xanthomonadales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_210736_2	457398.HMPREF0326_03019	7.84e-155	456.0	COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,42UU6@68525|delta/epsilon subdivisions,2X85I@28221|Deltaproteobacteria,2MCJ2@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210736_6	1397284.AYMN01000002_gene2281	8.13e-07	50.1	2DN5T@1|root,32VQG@2|Bacteria,1N6A1@1224|Proteobacteria,1SB7Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109012_1	631362.Thi970DRAFT_01415	9.47e-53	179.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1S44I@1236|Gammaproteobacteria,1WYJP@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_102290_1	1121875.KB907548_gene1333	2.01e-35	137.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1HYC9@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
k59_20983_1	1249627.D779_0261	4.3e-61	190.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1TJD2@1236|Gammaproteobacteria,1WYEP@135613|Chromatiales	135613|Chromatiales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_20983_2	105559.Nwat_2233	1.74e-07	49.7	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,1WZ1N@135613|Chromatiales	135613|Chromatiales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
k59_81970_1	1182590.BN5_00535	1.55e-16	80.9	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1YCRM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_81970_2	1266908.AQPB01000037_gene472	1.49e-11	64.7	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_122587_1	1168034.FH5T_12510	1.72e-32	122.0	2E9C0@1|root,333JQ@2|Bacteria,4NVAR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156533_1	401053.AciPR4_0698	9.64e-32	116.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_210748_1	1129794.C427_0493	5.24e-68	219.0	COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,1RQPZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
k59_20994_1	533240.CRC_03300	1.73e-16	80.9	2DBFF@1|root,2Z8YA@2|Bacteria,1G2KB@1117|Cyanobacteria,1HPNV@1161|Nostocales	1117|Cyanobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_7326_1	1305735.JAFT01000005_gene3873	1.05e-16	80.1	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	-	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_88740_2	242527.Q6V7M7_9CAUD	7.83e-19	86.3	4QDZP@10239|Viruses,4R039@35237|dsDNA viruses  no RNA stage,4QSG5@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61622_1	1223410.KN050846_gene2828	8.42e-09	61.2	2E3AK@1|root,32YA3@2|Bacteria,4NUYM@976|Bacteroidetes,1I4YQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_21000_1	1165841.SULAR_01345	3.81e-179	525.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_183984_1	870187.Thini_0482	1.85e-54	185.0	COG1100@1|root,COG1100@2|Bacteria,1R1W9@1224|Proteobacteria,1SK3H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
k59_50796_1	1211777.BN77_1626	1.77e-07	54.7	COG2304@1|root,COG2304@2|Bacteria,1PXSC@1224|Proteobacteria,2UFIR@28211|Alphaproteobacteria,4BFD2@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4381)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4381
k59_50796_2	926562.Oweho_0047	2.95e-53	178.0	COG2304@1|root,COG2304@2|Bacteria,4NFAV@976|Bacteroidetes,1I0D8@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_10114_1	2340.JV46_27420	3.72e-45	157.0	COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k59_71037_1	143224.JQMD01000002_gene3126	5.51e-100	310.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1HZK3@117743|Flavobacteriia	976|Bacteroidetes	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
k59_200040_1	745411.B3C1_11414	1.1e-60	204.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RRY3@1236|Gammaproteobacteria,1J69B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
k59_152494_1	565045.NOR51B_122	7.19e-83	256.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RQ0P@1236|Gammaproteobacteria,1JA4R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
k59_84850_1	886377.Murru_0844	2.05e-99	294.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
k59_84850_2	313603.FB2170_08689	1.14e-26	108.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia,2PGAJ@252356|Maribacter	976|Bacteroidetes	S	GldM C-terminal domain	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
k59_132159_1	65093.PCC7418_3291	2.82e-62	217.0	COG0438@1|root,COG0457@1|root,COG1216@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG1216@2|Bacteria,1G7V8@1117|Cyanobacteria	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_125346_1	234267.Acid_1964	3.26e-33	131.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_36952_1	1157708.KB907463_gene721	9.29e-36	129.0	COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,2VT03@28216|Betaproteobacteria,4AHAF@80864|Comamonadaceae	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_36952_2	981327.F925_00858	4.29e-05	46.6	COG3152@1|root,COG3152@2|Bacteria,1NJBD@1224|Proteobacteria,1SUAU@1236|Gammaproteobacteria,3NNCX@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
k59_84851_1	570967.JMLV01000001_gene2955	2.42e-61	213.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JQTV@204441|Rhodospirillales	204441|Rhodospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	vexF	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_16869_1	1198232.CYCME_0830	1.87e-120	355.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_30608_1	749222.Nitsa_0031	7.05e-62	196.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2YP6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0831	CoaE
k59_165914_1	1168034.FH5T_17465	4.4e-87	257.0	2DMQT@1|root,32T2H@2|Bacteria,4NN19@976|Bacteroidetes,2FWYX@200643|Bacteroidia	976|Bacteroidetes	I	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k59_165914_2	398720.MED217_08635	7e-28	103.0	2DB76@1|root,2Z7JZ@2|Bacteria,4NQDC@976|Bacteroidetes,1I2ER@117743|Flavobacteriia	976|Bacteroidetes	S	phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k59_36955_1	526222.Desal_1331	2.69e-71	229.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42ME4@68525|delta/epsilon subdivisions,2WJA5@28221|Deltaproteobacteria,2MA0T@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_71044_1	1217712.F971_03195	7.61e-06	50.8	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,3NN5N@468|Moraxellaceae	1236|Gammaproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_111721_2	264402.Cagra.0259s0017.1.p	1.98e-22	93.2	2CKHQ@1|root,2S5E8@2759|Eukaryota,37WKE@33090|Viridiplantae,3GKNN@35493|Streptophyta	35493|Streptophyta	S	BEST Arabidopsis thaliana protein match is Mitovirus RNA-dependent RNA polymerase (TAIR	-	-	-	-	-	-	-	-	-	-	-	-	Mitovir_RNA_pol
k59_30613_1	583345.Mmol_0976	0.000817	47.4	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KMD2@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
k59_200054_1	1056512.D515_04312	1.07e-45	151.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S5JT@1236|Gammaproteobacteria,1Y2RP@135623|Vibrionales	135623|Vibrionales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_172824_1	272943.RSP_3667	3.7e-05	52.8	COG1361@1|root,COG3188@1|root,COG1361@2|Bacteria,COG3188@2|Bacteria,1R5G4@1224|Proteobacteria,2UC86@28211|Alphaproteobacteria,1FCGH@1060|Rhodobacter	28211|Alphaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_64313_1	387093.SUN_0633	5.28e-68	231.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_105111_1	1168034.FH5T_04780	1.41e-108	322.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,2FN1B@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase, class I II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_152514_1	1082933.MEA186_17738	3.03e-38	144.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
k59_77832_1	1165841.SULAR_08267	1.74e-101	301.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_132190_1	688245.CtCNB1_3970	3.86e-50	163.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_71066_1	498761.HM1_0420	1.27e-19	95.5	COG0308@1|root,COG0308@2|Bacteria,1U6PC@1239|Firmicutes,24AYS@186801|Clostridia	186801|Clostridia	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_77843_1	886377.Murru_2406	3.41e-67	228.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_3520_1	756067.MicvaDRAFT_4620	1.93e-15	81.3	COG2114@1|root,COG2114@2|Bacteria,1GQRR@1117|Cyanobacteria,1H9GQ@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,PAS_4
k59_206800_1	460265.Mnod_6834	5.95e-20	89.4	COG2801@1|root,COG2801@2|Bacteria,1R471@1224|Proteobacteria,2U60M@28211|Alphaproteobacteria,1JTXS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_206800_2	1120956.JHZK01000057_gene1843	4.03e-16	74.7	COG2963@1|root,COG2963@2|Bacteria,1N75X@1224|Proteobacteria,2UIVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28
k59_77850_1	439235.Dalk_1095	6.71e-16	74.3	292SY@1|root,2ZQAN@2|Bacteria,1P40A@1224|Proteobacteria,433JE@68525|delta/epsilon subdivisions,2WYAR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_77850_2	269799.Gmet_1168	5.81e-08	54.3	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,43UIQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
k59_179273_1	999141.GME_04667	4.73e-29	104.0	COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1XKZ6@135619|Oceanospirillales	135619|Oceanospirillales	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k59_77852_1	744979.R2A130_2754	1.21e-97	292.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_159260_1	1189612.A33Q_1078	8.73e-09	61.6	COG2972@1|root,COG2972@2|Bacteria,4NRRA@976|Bacteroidetes,47V23@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_159260_2	381666.PHG266	3.11e-09	58.5	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1K518@119060|Burkholderiaceae	28216|Betaproteobacteria	K	regulator	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_71072_1	1232437.KL662019_gene627	4.38e-26	105.0	COG5659@1|root,COG5659@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_152540_1	395493.BegalDRAFT_2969	4.63e-31	120.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_105143_1	2340.JV46_16110	1.69e-93	304.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_179278_1	96561.Dole_3250	7.59e-85	266.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_71075_1	1165841.SULAR_03587	2.94e-129	392.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_213501_1	452637.Oter_1893	5.3e-13	74.3	COG0577@1|root,COG0577@2|Bacteria	452637.Oter_1893|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_50835_1	998088.B565_1393	4.48e-86	263.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1Y5GI@135624|Aeromonadales	135624|Aeromonadales	P	oligopeptide ABC transporter, ATP-binding protein	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_159703_1	717773.Thicy_0694	4.79e-81	250.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,45ZNU@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_213804_1	1448139.AI20_11020	1.34e-20	93.6	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_98884_1	717774.Marme_2668	2.32e-16	75.5	2CU57@1|root,333RB@2|Bacteria,1N95P@1224|Proteobacteria,1SZR2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78336_1	1165841.SULAR_02943	3.94e-45	155.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_78336_2	1165841.SULAR_02938	8.07e-57	191.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hydB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_146246_2	3694.POPTR_0019s08360.1	1.13e-13	72.0	KOG1075@1|root,KOG1075@2759|Eukaryota,37TIF@33090|Viridiplantae,3G9IZ@35493|Streptophyta,4JJZN@91835|fabids	35493|Streptophyta	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,RVT_1,RVT_3,zf-RVT
k59_159705_1	1288298.rosmuc_02772	3.26e-07	57.4	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46P2B@74030|Roseovarius	28211|Alphaproteobacteria	MQ	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Collar,HemolysinCabind,Peptidase_M10_C
k59_146248_1	886293.Sinac_2422	3.02e-31	121.0	COG0017@1|root,COG0017@2|Bacteria,2IWX6@203682|Planctomycetes	203682|Planctomycetes	J	PFAM tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_146248_2	1116472.MGMO_62c00020	5.59e-08	51.6	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1XFIW@135618|Methylococcales	135618|Methylococcales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_200443_1	1165841.SULAR_09269	5e-103	317.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_105596_1	396588.Tgr7_0079	1.48e-67	228.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_64733_1	314230.DSM3645_20627	1.9e-58	196.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_139293_1	309807.SRU_1523	8.75e-83	258.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1FINF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
k59_125807_1	398512.JQKC01000020_gene4016	2.03e-47	177.0	COG1609@1|root,COG4191@1|root,COG1609@2|Bacteria,COG4191@2|Bacteria,1UCKT@1239|Firmicutes,24GBZ@186801|Clostridia,3WNR7@541000|Ruminococcaceae	186801|Clostridia	KT	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Peripla_BP_3
k59_94751_1	321846.PS417_13330	3.67e-08	59.7	COG3568@1|root,COG3568@2|Bacteria,1R3X8@1224|Proteobacteria,1RZYH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_176043_1	1168034.FH5T_17700	1.87e-74	239.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FN98@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_162350_1	1232410.KI421413_gene672	6.73e-25	112.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_162350_3	743719.PaelaDRAFT_0080	0.000485	45.4	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,26QBQ@186822|Paenibacillaceae	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_67776_1	1168034.FH5T_17535	2.52e-111	330.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,2FNXA@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_13350_1	768671.ThimaDRAFT_4552	3.27e-131	389.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_169339_2	391038.Bphy_4268	7.1e-09	55.5	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VU6J@28216|Betaproteobacteria,1K3PA@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_209897_1	396588.Tgr7_3148	1.59e-90	283.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1WW7K@135613|Chromatiales	135613|Chromatiales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_189161_1	1286106.MPL1_03835	3.08e-111	337.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_203144_1	318167.Sfri_1960	1.23e-06	54.3	COG1463@1|root,COG1463@2|Bacteria,1PV9J@1224|Proteobacteria,1SWTW@1236|Gammaproteobacteria,2QD9I@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
k59_203144_2	596152.DesU5LDRAFT_3481	5.01e-22	95.9	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria,2M9P5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
k59_189162_1	1165841.SULAR_06403	1.88e-19	80.1	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_189162_2	1165841.SULAR_06408	4.78e-89	268.0	2ENEN@1|root,33G25@2|Bacteria,1NIJM@1224|Proteobacteria,42U7Y@68525|delta/epsilon subdivisions,2YPT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_176050_1	29760.VIT_00s0246g00010.t01	9.87e-52	173.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GKAG@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase ubiquinone iron-sulfur protein 2-like	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa
k59_155577_1	2340.JV46_05440	1.96e-27	111.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1J8EA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_128455_1	1132836.RCCGE510_03453	2.32e-06	53.9	2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria,2UK7H@28211|Alphaproteobacteria,4BIX3@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
k59_216488_1	1165841.SULAR_00855	3.73e-92	280.0	COG0767@1|root,COG3113@1|root,COG0767@2|Bacteria,COG3113@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	iamB	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
k59_169347_1	1379270.AUXF01000001_gene2204	3.35e-24	110.0	COG1074@1|root,COG1074@2|Bacteria,1ZUPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_176051_1	340177.Cag_1600	2.52e-162	466.0	COG3950@1|root,COG3950@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
k59_203154_1	1242864.D187_002081	1.64e-13	76.3	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YYM7@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_13372_1	1380387.JADM01000011_gene3537	1.34e-41	143.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1S04F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Metallopeptidase family M24	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_196293_1	1165841.SULAR_08909	1.91e-101	322.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_196293_2	1165841.SULAR_08914	1.54e-67	213.0	COG3301@1|root,COG3301@2|Bacteria,1QSRQ@1224|Proteobacteria,42PAY@68525|delta/epsilon subdivisions,2YN5Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_216495_1	1117314.PCIT_01218	1.76e-12	72.4	COG1262@1|root,COG2730@1|root,COG1262@2|Bacteria,COG2730@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,2Q17C@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,FGE-sulfatase
k59_142038_1	1280390.CBQR020000080_gene1773	1.45e-47	172.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26QNN@186822|Paenibacillaceae	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
k59_155593_1	662755.CRES_0924	5.37e-110	338.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,22KA8@1653|Corynebacteriaceae	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_203164_1	501479.ACNW01000062_gene2740	4.24e-48	169.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_33714_1	944547.ABLL_1272	2.81e-137	419.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_142040_1	457570.Nther_1888	1.97e-27	110.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia	186801|Clostridia	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_176058_1	1165841.SULAR_02428	1.36e-54	176.0	COG4902@1|root,COG4902@2|Bacteria	2|Bacteria	-	-	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	DUF2202
k59_176058_2	1165841.SULAR_02433	3e-76	236.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_60925_1	1123278.KB893553_gene3916	2.85e-23	95.9	COG3547@1|root,COG3547@2|Bacteria,4NGED@976|Bacteroidetes	976|Bacteroidetes	L	PFAM Transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_101431_1	1168034.FH5T_10245	1.71e-96	287.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,2FRI2@200643|Bacteroidia	976|Bacteroidetes	K	Chemotaxis protein CheY	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_33721_1	314278.NB231_09438	2.39e-29	107.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,1T11M@1236|Gammaproteobacteria,1X1AJ@135613|Chromatiales	135613|Chromatiales	S	Hemimethylated DNA-binding protein YccV like	-	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
k59_33721_2	391593.RCCS2_13809	8.63e-22	90.1	COG5485@1|root,COG5485@2|Bacteria,1N1VS@1224|Proteobacteria,2UG41@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
k59_26886_1	1165841.SULAR_08522	1.32e-37	135.0	COG3439@1|root,COG3439@2|Bacteria,1PWY7@1224|Proteobacteria,42Y9J@68525|delta/epsilon subdivisions,2YRF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26886_2	1165841.SULAR_08517	2.44e-67	213.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2YN5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_114403_1	338963.Pcar_1239	5.28e-46	159.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_114403_2	177439.DP1199	5.54e-30	115.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WQFN@28221|Deltaproteobacteria,2MKTB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,POR
k59_209939_1	1049564.TevJSym_ae00900	2.71e-144	412.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1J6D4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_196768_1	929558.SMGD1_1328	2.56e-87	280.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2YNIK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,dCache_1
k59_74735_1	177437.HRM2_41250	1.71e-20	89.0	2CH0K@1|root,32S50@2|Bacteria,1N3TK@1224|Proteobacteria,42U5H@68525|delta/epsilon subdivisions,2WQPD@28221|Deltaproteobacteria,2MJVI@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128894_1	88036.EFJ05008	1.26e-50	172.0	28ISP@1|root,2QR3X@2759|Eukaryota,37T53@33090|Viridiplantae,3G7SE@35493|Streptophyta	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbC	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_128894_2	4565.Traes_2AL_6C270714E1.1	7.43e-38	128.0	2C06H@1|root,2S7KE@2759|Eukaryota,37X2N@33090|Viridiplantae,3GM7I@35493|Streptophyta	35493|Streptophyta	S	Photosystem II reaction center protein Z	psbZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02724	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	Ycf9
k59_128894_3	4155.Migut.J01359.1.p	1.77e-60	186.0	COG0199@1|root,KOG1741@2759|Eukaryota,37VQM@33090|Viridiplantae,3GJZT@35493|Streptophyta	35493|Streptophyta	J	Binds 16S rRNA, required for the assembly of 30S particles	rps14	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_128894_4	4155.Migut.J01360.1.p	0.0	1520.0	28JJ8@1|root,2QRYE@2759|Eukaryota,37QY5@33090|Viridiplantae,3GH5Y@35493|Streptophyta,44Q5F@71274|asterids	35493|Streptophyta	C	Photosystem I psaA/psaB protein	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016168,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k59_128894_5	50452.W0USV0	0.0	1526.0	28JJ8@1|root,2QRYE@2759|Eukaryota,37RH7@33090|Viridiplantae,3GCW8@35493|Streptophyta,3I0SM@3699|Brassicales	35493|Streptophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0009987,GO:0010287,GO:0015979,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02689	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k59_128894_6	72664.XP_006404497.1	3.24e-49	158.0	COG0457@1|root,KOG1124@2759|Eukaryota,37TZH@33090|Viridiplantae,3GKZ9@35493|Streptophyta	35493|Streptophyta	S	Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits	ycf3	-	-	-	-	-	-	-	-	-	-	-	TPR_1
k59_128894_9	4155.Migut.D01426.1.p	2.61e-131	374.0	COG0522@1|root,KOG3301@2759|Eukaryota,37TGK@33090|Viridiplantae,3G7BN@35493|Streptophyta,44PVZ@71274|asterids	35493|Streptophyta	J	Ribosomal protein S4/S9 N-terminal domain	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_128894_10	3880.AES88239	2.79e-10	60.1	COG0522@1|root,KOG3301@2759|Eukaryota,37TGK@33090|Viridiplantae,3G7BN@35493|Streptophyta	35493|Streptophyta	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_128894_11	4155.Migut.D01427.1.p	1.5e-118	338.0	COG0852@1|root,KOG1713@2759|Eukaryota,37QGD@33090|Viridiplantae,3GGF5@35493|Streptophyta,44PBS@71274|asterids	35493|Streptophyta	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	ndhJ	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K05581	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_30kDa
k59_128894_12	4155.Migut.D01428.1.p	5.34e-154	435.0	COG0377@1|root,KOG1687@2759|Eukaryota,37QTD@33090|Viridiplantae,3GHED@35493|Streptophyta,44RGU@71274|asterids	35493|Streptophyta	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	ndhK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3	ko:K05582	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q6
k59_128894_13	3847.GLYMA13G04690.2	1.06e-72	219.0	COG0838@1|root,KOG4662@2759|Eukaryota,37UN0@33090|Viridiplantae,3GISB@35493|Streptophyta,4JUVD@91835|fabids	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008137,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
k59_190009_1	2340.JV46_14530	6.2e-122	373.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1J56P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_128895_1	1121875.KB907550_gene863	6.85e-111	344.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_34122_1	1260251.SPISAL_06450	1e-23	97.8	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1WXGF@135613|Chromatiales	135613|Chromatiales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_34122_2	2340.JV46_26480	6.71e-46	155.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1J4MN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
k59_40867_1	1254432.SCE1572_13025	4.43e-44	158.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Metallophos
k59_176431_1	398720.MED217_15065	1e-30	112.0	COG2963@1|root,COG2963@2|Bacteria,4NRTR@976|Bacteroidetes,1I3TE@117743|Flavobacteriia	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_176431_2	616991.JPOO01000003_gene337	1.32e-102	306.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,23I5E@178469|Arenibacter	976|Bacteroidetes	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_156107_1	1288826.MSNKSG1_00536	5.94e-08	50.4	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_156107_2	1415778.JQMM01000001_gene2178	7.85e-107	314.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_20571_2	1121459.AQXE01000019_gene1898	1.51e-68	221.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria,2M8PV@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_183188_1	396588.Tgr7_0997	4.58e-115	349.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales	135613|Chromatiales	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_128898_2	261292.Nit79A3_0750	1.14e-40	140.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,2WGF2@28216|Betaproteobacteria,371P0@32003|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_56161_1	756067.MicvaDRAFT_0255	6.03e-40	151.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H6ZY@1150|Oscillatoriales	1117|Cyanobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,Methyltransf_25,Methyltransf_31,PP-binding,Thioesterase
k59_96963_1	595460.RRSWK_01941	1.28e-91	281.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_198750_1	72658.Bostr.21524s0001.1.p	7.47e-55	173.0	COG1007@1|root,KOG4668@2759|Eukaryota,37WKT@33090|Viridiplantae,3GKHT@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_49614_1	1165841.SULAR_07128	2.31e-30	115.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2YMR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_49614_2	1165841.SULAR_07138	1.33e-56	182.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2YMU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_8675_1	1296416.JACB01000001_gene3282	1.19e-12	75.5	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia,2YKBW@290174|Aquimarina	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
k59_76476_1	869213.JCM21142_62415	5.39e-84	271.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,47K7I@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_123986_1	269796.Rru_A0223	4.48e-60	202.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,2JPV0@204441|Rhodospirillales	204441|Rhodospirillales	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_191808_1	391937.NA2_07939	4.1e-13	73.2	COG4246@1|root,COG4246@2|Bacteria,1RENT@1224|Proteobacteria,2UV3Q@28211|Alphaproteobacteria,43Q87@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_83530_1	313603.FB2170_07055	3.46e-35	138.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia,2PGID@252356|Maribacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_144210_1	1168034.FH5T_08890	6.18e-66	210.0	2C793@1|root,2Z9MK@2|Bacteria,4NI6K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_63101_1	338963.Pcar_0577	3.88e-153	446.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria,43W2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_83533_1	1288826.MSNKSG1_14142	4.82e-53	181.0	COG0531@1|root,COG0531@2|Bacteria,1NCSX@1224|Proteobacteria,1RND7@1236|Gammaproteobacteria,4695V@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Amino acid permease	yjeH	GO:0000099,GO:0000101,GO:0000102,GO:0001101,GO:0003333,GO:0003674,GO:0005215,GO:0005294,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015191,GO:0015238,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015821,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043200,GO:0043865,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:1901680,GO:1901682,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K03757,ko:K03759,ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13,2.A.3.2	-	-	AA_permease_2
k59_178104_1	1333998.M2A_1327	3.15e-71	224.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	cation diffusion facilitator family transporter	zitB	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
k59_184990_1	713586.KB900536_gene1196	3.73e-56	188.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1WXXP@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_63105_1	1128421.JAGA01000003_gene2817	1.74e-12	66.6	COG0596@1|root,COG0596@2|Bacteria,2NQV9@2323|unclassified Bacteria	2|Bacteria	S	Alpha/beta hydrolase family	ybfF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_63105_2	1136138.JH604622_gene734	2.4e-34	127.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_144218_1	2340.JV46_20930	6.69e-104	313.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1J5IT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k59_171535_1	2340.JV46_18500	3.15e-83	266.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J57P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k59_90300_1	395493.BegalDRAFT_2621	1.19e-128	371.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,45ZZI@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_158036_1	491205.JARQ01000007_gene3068	1.38e-24	105.0	2EMFS@1|root,33F4H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
k59_144222_1	1541065.JRFE01000035_gene2800	1.62e-50	183.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4585@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4585@2|Bacteria,1GD97@1117|Cyanobacteria,3VI2Q@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,PAS_9,Pkinase,Response_reg
k59_15601_1	886293.Sinac_2777	4.38e-82	266.0	COG3119@1|root,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_76487_1	391625.PPSIR1_22976	4.08e-55	180.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,43BAG@68525|delta/epsilon subdivisions,2X6PP@28221|Deltaproteobacteria,2YUZG@29|Myxococcales	28221|Deltaproteobacteria	H	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
k59_103781_2	765913.ThidrDRAFT_0705	4.56e-50	167.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WX6I@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_164636_1	644076.SCH4B_0953	4.84e-95	297.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,4NBEB@97050|Ruegeria	28211|Alphaproteobacteria	S	hmm pf01979	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_42579_1	1165841.SULAR_06118	8.08e-169	481.0	COG4775@1|root,COG4775@2|Bacteria,1R536@1224|Proteobacteria	1224|Proteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_83547_1	650150.ERH_1142	3.85e-06	53.9	COG2971@1|root,COG2971@2|Bacteria,1V47Z@1239|Firmicutes,3VQIG@526524|Erysipelotrichia	526524|Erysipelotrichia	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_76489_1	1137799.GZ78_17130	2.29e-35	138.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1XHEA@135619|Oceanospirillales	135619|Oceanospirillales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_178117_1	319224.Sputcn32_3648	5.81e-29	116.0	COG3292@1|root,COG5001@1|root,COG3292@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8ZG@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y
k59_178117_2	1165096.ARWF01000001_gene609	1.06e-34	126.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KM5R@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k59_56188_1	340.xcc-b100_3008	9.36e-10	64.3	COG2199@1|root,COG2203@1|root,COG5278@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5278@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1X71E@135614|Xanthomonadales	135614|Xanthomonadales	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF
k59_96995_1	1134912.AJTV01000029_gene2059	1.16e-64	223.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2U0ZY@28211|Alphaproteobacteria,371BS@31993|Methylocystaceae	28211|Alphaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_35846_1	1165841.SULAR_09179	1.38e-155	461.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07648,ko:K07679	ko02020,ko02026,ko05133,map02020,map02026,map05133	M00456,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF_2,HATPase_c,HisKA,Hpt,PAS,Response_reg
k59_69832_1	13333.ERM96121	8.08e-84	248.0	COG0100@1|root,KOG0408@2759|Eukaryota,37UVR@33090|Viridiplantae,3GJ9B@35493|Streptophyta	35493|Streptophyta	J	Belongs to the universal ribosomal protein uS11 family	rps11	GO:0000028,GO:0000313,GO:0000314,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0031974,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070013,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0098798,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_69832_2	4155.Migut.D01434.1.p	7.42e-209	582.0	COG0202@1|root,2QRS7@2759|Eukaryota,37QVG@33090|Viridiplantae,3GHDB@35493|Streptophyta,44N87@71274|asterids	35493|Streptophyta	K	Bacterial RNA polymerase, alpha chain C terminal domain	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0031976,GO:0031984,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_69832_3	4577.GRMZM5G884960_P01	8.13e-124	352.0	COG1290@1|root,KOG4663@2759|Eukaryota,37NKU@33090|Viridiplantae,3G85T@35493|Streptophyta,3KZB0@4447|Liliopsida,3IH6E@38820|Poales	35493|Streptophyta	C	Cytochrome b6-f complex subunit 4	petD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02637	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B_C
k59_69832_4	4577.GRMZM5G800780_P01	1.44e-161	452.0	COG1290@1|root,KOG4663@2759|Eukaryota,37QS7@33090|Viridiplantae,3GHBB@35493|Streptophyta,3KUYY@4447|Liliopsida,3IBNR@38820|Poales	35493|Streptophyta	C	Cytochrome b6	petB	-	-	ko:K02635	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrome_B
k59_69832_5	50452.A0A087GI96	1.84e-41	137.0	2E1MV@1|root,2S8Y7@2759|Eukaryota,37WT7@33090|Viridiplantae,3GKK7@35493|Streptophyta	35493|Streptophyta	S	One of the components of the core complex of photosystem II (PSII), required for its stability and or assembly. PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbH	-	-	ko:K02709	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbH
k59_69832_6	59689.Al_scaffold_0002_946	0.0	1050.0	28JG1@1|root,2QRV6@2759|Eukaryota,37HEX@33090|Viridiplantae,3GE8P@35493|Streptophyta,3HZ99@3699|Brassicales	35493|Streptophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_69832_7	57918.XP_004309412.1	1.39e-75	227.0	COG0740@1|root,KOG0840@2759|Eukaryota,37U4N@33090|Viridiplantae,3GICU@35493|Streptophyta,4JUJ9@91835|fabids	35493|Streptophyta	O	ATP-dependent Clp protease proteolytic	clpP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_69832_8	59689.fgenesh1_pm.C_scaffold_2000590	2.94e-41	139.0	COG0740@1|root,KOG0840@2759|Eukaryota,37U4N@33090|Viridiplantae,3GICU@35493|Streptophyta	35493|Streptophyta	O	ATP-dependent Clp protease proteolytic subunit	clpP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_171794_2	317025.Tcr_1800	8.56e-71	223.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,46262@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
k59_171795_1	1396418.BATQ01000118_gene4606	1.33e-49	179.0	COG0492@1|root,COG1053@1|root,COG4409@1|root,COG0492@2|Bacteria,COG1053@2|Bacteria,COG4409@2|Bacteria,46TCP@74201|Verrucomicrobia	74201|Verrucomicrobia	CEGO	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,FAD_oxidored,SASA
k59_137779_1	1165841.SULAR_00720	9.39e-99	293.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2YN34@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_83769_1	34506.g2130	2.98e-52	186.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,40G12@6231|Nematoda,1KYNR@119089|Chromadorea,40UXW@6236|Rhabditida	33208|Metazoa	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,DapB_C,DapB_N,GATase,MGS
k59_158260_2	1268068.PG5_18210	7.33e-33	125.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	May be involved in recombination	rdgC	GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009295,GO:0019219,GO:0019222,GO:0031323,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k59_9070_1	629265.PMA4326_26842	1.16e-13	72.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1Z7FK@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	T	Sensory box protein response regulator	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_9070_2	1278073.MYSTI_04168	8.36e-32	123.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
k59_49984_1	118005.AWNK01000008_gene480	7.41e-24	100.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_69991_1	29730.Gorai.001G161100.1	1.94e-07	52.0	2C1H7@1|root,2R1WB@2759|Eukaryota,383JX@33090|Viridiplantae,3GQ6A@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15927_1	4081.Solyc03g005540.1.1	4.71e-69	234.0	28JZP@1|root,2QSE3@2759|Eukaryota,37QZD@33090|Viridiplantae,3GGZ7@35493|Streptophyta	35493|Streptophyta	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	DBD_Tnp_Mut,MULE,SWIM
k59_178361_1	1121013.P873_06875	1.07e-18	84.7	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1X3MQ@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_178361_2	443152.MDG893_09656	4.81e-26	103.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,468BK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Modulates RecA activity	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k59_178361_3	380394.Lferr_1050	3.53e-06	49.3	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,2NCJ6@225057|Acidithiobacillales	225057|Acidithiobacillales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_9075_1	1165841.SULAR_08272	3.03e-34	124.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2YNGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_9075_2	1165841.SULAR_08282	8.96e-49	162.0	2AHSQ@1|root,31858@2|Bacteria,1PZUK@1224|Proteobacteria,42XTR@68525|delta/epsilon subdivisions,2YQVH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3972
k59_124297_1	1123401.JHYQ01000046_gene2202	1.42e-44	159.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,45ZNH@72273|Thiotrichales	72273|Thiotrichales	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
k59_151423_1	411489.CLOL250_02823	4e-07	55.5	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,36E5T@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_151423_2	880072.Desac_1595	5.82e-14	71.2	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria,2MRHF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_164867_1	7425.NV19139-PA	1.01e-19	93.6	COG2801@1|root,KOG0017@2759|Eukaryota,39NC5@33154|Opisthokonta,3CPWT@33208|Metazoa,3E61X@33213|Bilateria,42B4I@6656|Arthropoda,3T0IH@50557|Insecta,46N17@7399|Hymenoptera	33208|Metazoa	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_104038_1	1165841.SULAR_04472	2.53e-73	226.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_104038_2	1165841.SULAR_04467	8.46e-46	158.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_137801_1	395493.BegalDRAFT_0442	9.76e-98	316.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_212412_1	1165841.SULAR_06228	1.59e-78	236.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42U2T@68525|delta/epsilon subdivisions,2YPV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_110783_1	543728.Vapar_1651	1.06e-80	256.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHQD@28216|Betaproteobacteria,4AAXG@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_131045_1	1218075.BAYA01000043_gene6604	1.84e-26	111.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VJJ7@28216|Betaproteobacteria,1K2F0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_42867_2	298386.PBPRB0091	2.95e-60	190.0	2C1A0@1|root,3329F@2|Bacteria,1N99D@1224|Proteobacteria,1SD1S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Type VI secretion system (T6SS), amidase effector protein 4	-	-	-	-	-	-	-	-	-	-	-	-	Tae4
k59_90587_1	1165841.SULAR_04097	7.76e-111	336.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2YMWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_110791_1	643473.KB235930_gene1881	2.63e-05	55.8	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1GJ9G@1117|Cyanobacteria,1HR22@1161|Nostocales	1117|Cyanobacteria	QU	PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	DUF4347,Lactonase
k59_158292_1	1165841.SULAR_10354	1.86e-74	224.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2YNZC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_158292_2	387093.SUN_0133	6.01e-81	240.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2YP65@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_158292_3	1165841.SULAR_10364	4.76e-31	121.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_137824_1	1459636.NTE_01583	9.38e-09	52.8	arCOG01588@1|root,arCOG01588@2157|Archaea,41STK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
k59_137824_2	1071085.KK033114_gene1690	7.76e-28	111.0	COG0189@1|root,arCOG01589@2157|Archaea,2XT8Z@28890|Euryarchaeota,23T5T@183963|Halobacteria	183963|Halobacteria	H	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	argX	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
k59_110794_1	1165841.SULAR_05828	1.01e-25	105.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_110794_2	1165841.SULAR_05833	5.65e-47	154.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2YMUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k59_24637_1	1165841.SULAR_08652	1.1e-54	176.0	2BSET@1|root,32MGT@2|Bacteria,1Q39R@1224|Proteobacteria,42WZN@68525|delta/epsilon subdivisions,2YQU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_24637_2	1165841.SULAR_08657	1.51e-55	191.0	COG0433@1|root,COG0433@2|Bacteria,1R7B1@1224|Proteobacteria,42NW4@68525|delta/epsilon subdivisions,2YM8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
k59_106175_1	1165841.SULAR_05588	6.79e-53	181.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_58573_1	387093.SUN_2093	2.01e-21	92.4	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_58573_2	1165841.SULAR_07118	1.51e-130	372.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42RGE@68525|delta/epsilon subdivisions,2YT0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_58573_3	1165841.SULAR_07123	1.81e-34	126.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_51760_1	1165841.SULAR_06388	1.48e-22	90.1	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2YNVK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k59_51760_2	1165841.SULAR_06383	8.59e-83	245.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2YPFW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_51760_3	1165841.SULAR_06378	6.9e-83	253.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2YN4H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_72010_1	857087.Metme_1384	3.52e-32	124.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XDJB@135618|Methylococcales	135618|Methylococcales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_72010_2	1286106.MPL1_10652	1.51e-58	184.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,460PC@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_4498_1	1279017.AQYJ01000029_gene3960	6.26e-69	232.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
k59_173596_1	1165841.SULAR_03642	8.69e-08	53.1	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_173596_2	1165841.SULAR_03637	1.3e-152	435.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_153469_1	1165841.SULAR_05733	6.54e-111	325.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_153469_2	1165841.SULAR_05738	4.17e-24	97.1	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2YMZQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_160295_1	1295642.H839_04799	6.18e-128	379.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,1WEQK@129337|Geobacillus	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
k59_85821_1	29760.VIT_00s1739g00010.t01	8.72e-78	233.0	2CDXT@1|root,2S1NU@2759|Eukaryota,37VRF@33090|Viridiplantae,3GJAF@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44752_1	2340.JV46_03620	5.23e-111	333.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1J4Z9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_58579_1	1165841.SULAR_02488	3.69e-75	236.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42USK@68525|delta/epsilon subdivisions,2YPZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_78821_1	2340.JV46_15350	3.57e-15	77.4	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RZVF@1236|Gammaproteobacteria,1JBWE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	NlpB/DapX lipoprotein	bamC	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_78821_2	497321.C664_11142	1.19e-14	73.2	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KUG2@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_133312_1	1165841.SULAR_09674	1.69e-153	439.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2YMJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_126332_2	472759.Nhal_2114	1.87e-81	245.0	29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,1S6VD@1236|Gammaproteobacteria,1X0VV@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_126332_3	396588.Tgr7_0590	5.3e-30	110.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,1SEFI@1236|Gammaproteobacteria,1WZTE@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146818_1	1165841.SULAR_00670	6.42e-113	328.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2YN88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_146818_2	1165841.SULAR_00665	4.2e-18	80.9	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_92530_2	983545.Glaag_1862	2.75e-32	119.0	COG0702@1|root,COG0702@2|Bacteria,1REY2@1224|Proteobacteria,1SYUB@1236|Gammaproteobacteria,4674D@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
k59_65729_1	880072.Desac_0501	9.98e-65	220.0	COG2202@1|root,COG2204@1|root,COG3290@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3290@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,Response_reg,Sigma54_activat
k59_86218_1	1298593.TOL_3243	4.68e-56	197.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XHH3@135619|Oceanospirillales	135619|Oceanospirillales	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_201240_1	522306.CAP2UW1_3159	1.26e-98	294.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_52138_1	46234.ANA_C11804	5.06e-37	143.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_25,PP-binding,Thioesterase
k59_160687_1	1392488.JHZY01000002_gene74	2.59e-39	138.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2XHXR@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Male sterility protein	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_160687_2	575540.Isop_1756	1.04e-10	62.8	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2IY6V@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_58986_1	313596.RB2501_02840	3.25e-58	199.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_187627_1	756272.Plabr_4675	1.78e-29	118.0	COG1845@1|root,COG1845@2|Bacteria,2IYXN@203682|Planctomycetes	203682|Planctomycetes	C	Heme copper-type cytochrome quinol oxidase, subunit	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_65737_1	1165841.SULAR_00080	4.48e-131	386.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_160690_1	1454004.AW11_02484	4.37e-129	371.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_120108_1	1121456.ATVA01000015_gene2472	1.08e-05	49.7	COG2120@1|root,COG2120@2|Bacteria,1MUTM@1224|Proteobacteria,42Q20@68525|delta/epsilon subdivisions,2WP8Q@28221|Deltaproteobacteria,2MCBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
k59_140168_1	1453505.JASY01000001_gene3645	3.97e-08	57.0	2DNQA@1|root,32YJG@2|Bacteria,4NXEN@976|Bacteroidetes,1IBF7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140168_2	1453505.JASY01000001_gene3646	2.79e-55	184.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HZ28@117743|Flavobacteriia,2NZZR@237|Flavobacterium	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
k59_153859_1	1174684.EBMC1_04314	4.59e-45	159.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,2K39Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
k59_92977_1	880073.Calab_1598	2.75e-54	192.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
k59_45267_2	1249627.D779_1746	3.39e-56	176.0	COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,1S5Y6@1236|Gammaproteobacteria,1WYHX@135613|Chromatiales	135613|Chromatiales	CQ	carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k59_45267_3	713587.THITH_12345	1.8e-32	115.0	COG4576@1|root,COG4576@2|Bacteria,1N7B1@1224|Proteobacteria,1S9JX@1236|Gammaproteobacteria,1WZ5P@135613|Chromatiales	135613|Chromatiales	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
k59_79211_1	1165841.SULAR_04457	2.55e-103	304.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_38155_1	2340.JV46_02880	3.89e-90	273.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1J8CF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518	Chorismate_synt
k59_38155_2	187272.Mlg_1227	2.69e-26	105.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1WWHF@135613|Chromatiales	135613|Chromatiales	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_208186_2	1123242.JH636435_gene1283	9.13e-48	169.0	COG0665@1|root,COG0665@2|Bacteria,2IX78@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
k59_167231_1	1408473.JHXO01000001_gene2118	2.55e-33	133.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,2FMGF@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_31883_1	550540.Fbal_3457	2.4e-138	403.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	'responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_133760_2	2340.JV46_05360	5.84e-101	300.0	COG2010@1|root,COG2010@2|Bacteria,1PDUJ@1224|Proteobacteria,1SUEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
k59_18410_1	1565129.JSFF01000015_gene36	2.96e-15	78.6	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,2QAN8@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM CBS domain containing protein	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_18410_2	768671.ThimaDRAFT_2890	1.91e-75	245.0	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales	135613|Chromatiales	M	HAD-superfamily hydrolase, subfamily IIB	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
k59_133761_1	313596.RB2501_02355	1.48e-26	106.0	COG4886@1|root,COG4886@2|Bacteria,4NUNJ@976|Bacteroidetes,1I5AX@117743|Flavobacteriia	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_126816_1	1122604.JONR01000006_gene2641	1.6e-06	55.8	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1X4TB@135614|Xanthomonadales	135614|Xanthomonadales	M	(Lipo)protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_147225_1	865937.Gilli_1969	2.14e-09	66.6	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	yeeJ	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
k59_120126_1	243090.RB9192	2.91e-40	148.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_86238_1	1321778.HMPREF1982_00108	4.43e-39	148.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_174064_1	313596.RB2501_09580	6.11e-69	214.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1IJPJ@117743|Flavobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_194634_2	1333998.M2A_0071	3.98e-104	305.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,4BQ02@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_194634_3	1532558.JL39_14340	5.9e-14	67.0	COG2350@1|root,COG2350@2|Bacteria,1PZSM@1224|Proteobacteria,2UGH8@28211|Alphaproteobacteria,4BN16@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_147226_1	870187.Thini_0478	1.86e-125	362.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,460H7@72273|Thiotrichales	72273|Thiotrichales	P	Binding-protein-dependent transport system inner membrane component	potI	-	-	ko:K11074	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
k59_147226_2	870187.Thini_0479	1.83e-79	243.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,460H1@72273|Thiotrichales	72273|Thiotrichales	P	Putrescine transport system permease	potH	-	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
k59_140182_1	1165841.SULAR_02668	3.01e-148	423.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_180834_1	1250232.JQNJ01000001_gene1139	2.89e-58	193.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
k59_54566_2	749222.Nitsa_0934	9.29e-16	75.1	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,42VS9@68525|delta/epsilon subdivisions,2YQD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Cytochrome c family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_95206_1	1240350.AMZE01000116_gene950	3.16e-12	71.6	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-associated metal-dependent hydrolase	eptA	-	2.7.8.43	ko:K03760,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_108773_1	247634.GPB2148_2927	4.26e-55	178.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1J554@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO1056	Acetyltransf_11,Hexapep
k59_20739_1	1116375.VEJY3_06860	2.35e-92	275.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1XUS7@135623|Vibrionales	135623|Vibrionales	E	Urea ABC transporter ATP-binding protein	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
k59_20739_2	765913.ThidrDRAFT_2226	1.58e-23	97.1	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1RSB2@1236|Gammaproteobacteria,1WX39@135613|Chromatiales	135613|Chromatiales	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
k59_115573_2	582402.Hbal_1577	1.35e-12	68.2	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,43XS6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF502)	MA20_12960	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_41026_2	1038859.AXAU01000002_gene274	7.87e-24	100.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TSX9@28211|Alphaproteobacteria,3JRBX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	BQ	Histone deacetylase domain	MA20_07590	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_88492_1	323097.Nham_2326	8.23e-20	95.1	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,3JSQ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_190183_1	396588.Tgr7_1735	4.46e-66	211.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_190183_2	1411685.U062_01561	1.11e-12	64.7	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1J60V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0784 FOG CheY-like receiver	pilG	-	-	ko:K02657,ko:K03413	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_81695_1	247639.MGP2080_05452	0.000357	47.4	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	crp	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,cNMP_binding
k59_20752_1	1179778.PMM47T1_13900	7.36e-67	236.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5067,P22_portal,Pkinase
k59_61403_1	1168034.FH5T_18200	2.75e-118	342.0	COG0450@1|root,COG0450@2|Bacteria	2|Bacteria	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_68184_1	1249627.D779_2236	1.8e-59	193.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales	135613|Chromatiales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_20756_1	313596.RB2501_09020	5.63e-102	302.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility	gldN	-	-	-	-	-	-	-	-	-	-	-	-
k59_20756_2	313603.FB2170_08689	1.47e-46	162.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia,2PGAJ@252356|Maribacter	976|Bacteroidetes	S	GldM C-terminal domain	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
k59_163043_1	880070.Cycma_0322	4.33e-57	196.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,47JX4@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_74867_2	1267535.KB906767_gene3318	6.27e-36	134.0	COG0665@1|root,COG0665@2|Bacteria,3Y6FK@57723|Acidobacteria,2JKN4@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_129068_1	1165841.SULAR_07590	2.58e-50	173.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_176576_1	13735.ENSPSIP00000020659	2.14e-50	169.0	COG1622@1|root,KOG4767@2759|Eukaryota,38FF8@33154|Opisthokonta,3BEBX@33208|Metazoa,3D20G@33213|Bilateria,48627@7711|Chordata,4991G@7742|Vertebrata	33208|Metazoa	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	COX2	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006140,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007589,GO:0007595,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010310,GO:0010562,GO:0010726,GO:0010728,GO:0010729,GO:0010939,GO:0010940,GO:0010941,GO:0010942,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030808,GO:0030810,GO:0030879,GO:0031090,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0045935,GO:0045937,GO:0045981,GO:0046034,GO:0046483,GO:0046903,GO:0048513,GO:0048518,GO:0048522,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0050878,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051194,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0080090,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901135,GO:1901360,GO:1901564,GO:1902600,GO:1903426,GO:1903428,GO:1903578,GO:1903580,GO:2000377,GO:2000379,GO:2001169,GO:2001171	-	ko:K02261	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX2,COX2_TM
k59_82242_1	360107.CHAB381_1783	6.64e-26	102.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2YP3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_122810_1	1452718.JBOY01000137_gene1482	3.99e-63	220.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5067,P22_portal,Pkinase
k59_211017_1	3760.EMJ04651	9.55e-06	47.4	KOG1075@1|root,KOG1075@2759|Eukaryota,37TIF@33090|Viridiplantae,3G9IZ@35493|Streptophyta	35493|Streptophyta	L	ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3,zf-RVT
k59_190718_1	472759.Nhal_0712	1.47e-85	269.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_7519_1	1165841.SULAR_09039	1.42e-35	129.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_7519_2	1442598.JABW01000005_gene448	1.96e-38	132.0	COG1393@1|root,COG1393@2|Bacteria,1QDI7@1224|Proteobacteria,42U8X@68525|delta/epsilon subdivisions,2YPXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_7519_3	1165841.SULAR_09029	3.66e-49	157.0	COG0721@1|root,COG0721@2|Bacteria,1Q61J@1224|Proteobacteria,42VIQ@68525|delta/epsilon subdivisions,2YQAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_7519_4	1165841.SULAR_09024	8.56e-74	221.0	COG4802@1|root,COG4802@2|Bacteria,1QYD3@1224|Proteobacteria,42PN1@68525|delta/epsilon subdivisions,2YMYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B,Rhodanese
k59_7519_5	1165841.SULAR_09019	2.86e-62	192.0	COG0607@1|root,COG0607@2|Bacteria,1PX2U@1224|Proteobacteria,434B7@68525|delta/epsilon subdivisions,2YSA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_75371_1	2340.JV46_18630	9.84e-10	55.1	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1JBXM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_75371_2	187272.Mlg_2612	3.95e-15	70.9	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_75371_3	519989.ECTPHS_01534	1.9e-18	79.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1WYHH@135613|Chromatiales	135613|Chromatiales	E	phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
k59_102556_1	857087.Metme_1625	9.63e-17	73.6	COG0633@1|root,COG0633@2|Bacteria,1MZW3@1224|Proteobacteria,1SAM4@1236|Gammaproteobacteria,1XFHE@135618|Methylococcales	135618|Methylococcales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_102556_2	870187.Thini_0805	3.08e-62	192.0	COG0633@1|root,COG0633@2|Bacteria,1N22M@1224|Proteobacteria,1S5ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_55098_1	1165841.SULAR_07128	2.22e-157	447.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2YMR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_48317_1	278957.ABEA03000040_gene3884	1.65e-46	167.0	COG0029@1|root,COG0029@2|Bacteria,46SHQ@74201|Verrucomicrobia,3K72T@414999|Opitutae	414999|Opitutae	H	L-aspartate oxidase	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_89076_1	1165841.SULAR_00440	4e-44	149.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_89076_2	1123326.JFBL01000004_gene2135	7.49e-32	115.0	293MU@1|root,2ZR3M@2|Bacteria,1REEY@1224|Proteobacteria	1224|Proteobacteria	S	Superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
k59_116086_2	1894.JOER01000019_gene4205	1.45e-10	62.8	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_3
k59_55099_1	1453501.JELR01000002_gene302	3.72e-19	85.9	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,468DI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_197483_1	929558.SMGD1_1615	6.36e-64	210.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_211030_1	243233.MCA0813	1.24e-88	274.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,1RS93@1236|Gammaproteobacteria,1XE11@135618|Methylococcales	135618|Methylococcales	I	PFAM Squalene phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
k59_116092_1	2340.JV46_17600	4.15e-22	92.0	COG3151@1|root,COG3151@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1249)	yqiB	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
k59_116092_2	2340.JV46_17650	1.09e-38	132.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1J5XB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_211031_1	887062.HGR_12427	8.35e-76	237.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,4AA26@80864|Comamonadaceae	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_48322_1	439235.Dalk_3968	8.71e-65	214.0	COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
k59_28031_1	1123401.JHYQ01000003_gene2144	2.34e-61	195.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales	72273|Thiotrichales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_862_1	743722.Sph21_4674	1.82e-21	98.6	28JBH@1|root,2Z967@2|Bacteria,4NNHF@976|Bacteroidetes,1IU8H@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
k59_82263_1	1232437.KL662008_gene3438	2.05e-37	139.0	COG4191@1|root,COG4191@2|Bacteria,1R682@1224|Proteobacteria,42P91@68525|delta/epsilon subdivisions,2WKQI@28221|Deltaproteobacteria,2MJEK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
k59_116102_1	1122132.AQYH01000002_gene1283	3.79e-151	441.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,4BAGU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_143220_1	395964.KE386496_gene1028	0.000392	42.4	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,3NAE5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_143220_2	1165841.SULAR_09114	6.73e-72	222.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_14472_1	1211777.BN77_p10815	9.89e-77	248.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_95726_1	90675.XP_010462734.1	1.49e-18	86.3	COG2801@1|root,KOG0017@2759|Eukaryota,37TRV@33090|Viridiplantae,3GJ4K@35493|Streptophyta	35493|Streptophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3
k59_170344_2	1215092.PA6_009_00300	2.93e-30	118.0	28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P22 coat protein-protein 5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45021_1	180332.JTGN01000002_gene5677	2.95e-58	191.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_153678_1	1144305.PMI02_05429	6.46e-39	138.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TQNZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_139983_1	2340.JV46_07160	2.13e-65	200.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1J67P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_139983_2	396588.Tgr7_2304	3.51e-72	230.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales	135613|Chromatiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_194374_1	759914.BP951000_1262	4.99e-40	155.0	COG0841@1|root,COG0841@2|Bacteria,2J5HW@203691|Spirochaetes	203691|Spirochaetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_194374_2	1415779.JOMH01000001_gene449	0.000856	42.7	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3PQ@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_18210_1	1178482.BJB45_12045	1.02e-100	314.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHCN@135619|Oceanospirillales	135619|Oceanospirillales	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_147046_1	1136138.JH604622_gene1529	6.49e-60	191.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_37999_1	321846.PS417_08395	1.32e-21	99.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	ybbP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_139986_1	305700.B447_03583	9.78e-36	135.0	COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria	1224|Proteobacteria	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_187400_1	251229.Chro_5503	5.28e-31	126.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG5001@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5001@2|Bacteria,1GIUR@1117|Cyanobacteria,3VIDX@52604|Pleurocapsales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,Pkinase
k59_153684_1	1122176.KB903532_gene2757	9.2e-22	85.1	29AQG@1|root,2ZXQ8@2|Bacteria,4P7I4@976|Bacteroidetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_147049_2	323261.Noc_0349	4.14e-07	52.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
k59_112614_1	313596.RB2501_01605	7.18e-102	315.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_119979_1	316273.XCV0180	1.38e-12	68.2	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,1S7SZ@1236|Gammaproteobacteria,1X5QD@135614|Xanthomonadales	135614|Xanthomonadales	I	acetyltransferase	plsC1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_133973_1	102129.Lepto7375DRAFT_2225	8.96e-108	338.0	COG0370@1|root,COG0370@2|Bacteria,1G058@1117|Cyanobacteria,1H8CQ@1150|Oscillatoriales	1117|Cyanobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_181016_1	426114.THI_1412	1.57e-34	127.0	COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria	1224|Proteobacteria	S	protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
k59_106900_1	502025.Hoch_1221	8.44e-94	291.0	COG3385@1|root,COG3385@2|Bacteria,1NBHF@1224|Proteobacteria,43BBP@68525|delta/epsilon subdivisions,2WRX0@28221|Deltaproteobacteria,2Z20S@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_194801_2	556268.OFAG_02357	3.75e-29	107.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,474RM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_194801_3	1049564.TevJSym_as00540	6.98e-16	79.3	29QAQ@1|root,30B9W@2|Bacteria,1RGQ5@1224|Proteobacteria,1S5E4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154029_1	1121937.AUHJ01000012_gene2772	1.55e-102	310.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,464AY@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	cbrB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k59_79462_1	1122981.AUME01000010_gene1336	3.65e-54	180.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,2FMCQ@200643|Bacteroidia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
k59_86373_1	631362.Thi970DRAFT_03848	1.78e-35	131.0	2DWAQ@1|root,33ZBQ@2|Bacteria,1P92K@1224|Proteobacteria,1STZN@1236|Gammaproteobacteria,1X201@135613|Chromatiales	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79465_1	5334.XP_003026879.1	0.00041	42.7	COG1028@1|root,KOG1200@2759|Eukaryota,39JM4@33154|Opisthokonta,3Q3YC@4751|Fungi,3VCKV@5204|Basidiomycota,22FC8@155619|Agaricomycetes,3W93M@5338|Agaricales	4751|Fungi	Q	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_79465_2	1165841.SULAR_05893	2.79e-102	300.0	COG3038@1|root,COG3038@2|Bacteria,1NC3G@1224|Proteobacteria,42SCY@68525|delta/epsilon subdivisions,2YQ0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_79465_3	1165841.SULAR_02008	7.94e-17	79.3	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_214723_1	1123400.KB904813_gene3071	2.16e-77	243.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_106906_1	1165841.SULAR_01090	7.3e-49	155.0	COG1144@1|root,COG1144@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	forE	-	1.2.7.1	ko:K00171,ko:K00172,ko:K02573,ko:K13795,ko:K18930	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4,Fer4_21,Fer4_4,Fer4_7,POR
k59_106906_2	1165841.SULAR_01095	6.32e-110	317.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	CO_dh,PBP_like_2
k59_99918_1	95619.PM1_0203065	4.97e-33	133.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	transport system, permease component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_147397_1	1178825.ALIH01000009_gene1260	6.25e-19	91.3	COG2273@1|root,COG3291@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_59152_1	1165841.SULAR_04172	2.9e-30	118.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_59152_2	1165841.SULAR_04167	4.16e-80	251.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_120335_1	1230343.CANP01000039_gene2963	1.74e-09	59.3	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1P31Y@1224|Proteobacteria,1RQNS@1236|Gammaproteobacteria,1JCIJ@118969|Legionellales	118969|Legionellales	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_120335_2	392499.Swit_3883	1.3e-24	102.0	COG0331@1|root,COG0331@2|Bacteria,1MW5Y@1224|Proteobacteria,2TT74@28211|Alphaproteobacteria,2K3K6@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-carrier-protein s-malonyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201461_1	985054.JQEZ01000004_gene806	2.57e-42	153.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4ND0W@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_201461_2	77586.LPERR02G04860.1	1.23e-18	84.7	COG1012@1|root,KOG2730@1|root,KOG2451@2759|Eukaryota,KOG2730@2759|Eukaryota,37Q0D@33090|Viridiplantae,3G9A0@35493|Streptophyta,3KY7I@4447|Liliopsida,3ICJH@38820|Poales	35493|Streptophyta	C	Belongs to the aldehyde dehydrogenase family	-	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019752,GO:0031974,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.24	ko:K17761	ko00250,ko00650,ko01100,map00250,map00650,map01100	-	R00713	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_45520_1	187272.Mlg_0035	8.45e-10	55.8	COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,1WZ84@135613|Chromatiales	135613|Chromatiales	H	TIGRFAM thiamine biosynthesis protein ThiS	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_45520_2	1049564.TevJSym_bv00110	1.72e-33	128.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1J5PE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_65982_1	595460.RRSWK_00180	3.77e-152	442.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Fucosidase_C
k59_72718_1	1168034.FH5T_06525	9.79e-93	296.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_181042_2	1219072.VHA01S_028_00290	2.14e-11	64.3	2E65Y@1|root,330UM@2|Bacteria,1N8U3@1224|Proteobacteria,1SCHF@1236|Gammaproteobacteria,1Y278@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_147400_1	1278307.KB907070_gene2698	8.07e-39	143.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transposase, IS801 IS1294	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_120339_1	13333.ERN02870	3.75e-181	507.0	2CMAK@1|root,2QPT8@2759|Eukaryota,37MKA@33090|Viridiplantae,3GD5I@35493|Streptophyta	35493|Streptophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N,CemA
k59_25117_1	1121007.AUML01000010_gene3329	1.28e-37	142.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2YHMP@290174|Aquimarina	976|Bacteroidetes	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_208381_1	675813.VIB_001783	0.000732	47.8	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XTC4@135623|Vibrionales	135623|Vibrionales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_120348_1	1049564.TevJSym_bo00020	6.51e-204	577.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
k59_32098_2	387093.SUN_1196	4.07e-66	216.0	COG0665@1|root,COG0665@2|Bacteria,1QV9J@1224|Proteobacteria,42PP0@68525|delta/epsilon subdivisions,2YNBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_45540_1	983917.RGE_15860	5.05e-42	157.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VMZD@28216|Betaproteobacteria,1KK64@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_3
k59_181056_1	1165841.SULAR_06738	2.69e-68	223.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42Z4X@68525|delta/epsilon subdivisions,2YRD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_181056_2	1165841.SULAR_06733	2.99e-27	110.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_93195_1	1250232.JQNJ01000001_gene2467	4.16e-18	79.7	2AH1X@1|root,317B1@2|Bacteria,4P85G@976|Bacteroidetes,1IB1V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5224_1	2340.JV46_07310	4.42e-90	268.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1J4GK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_5224_2	2340.JV46_07320	1.15e-17	76.3	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1J668@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_106930_1	1173264.KI913949_gene944	4.02e-30	123.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_7,PAS_8,PAS_9,Response_reg
k59_187867_2	357804.Ping_0396	3.38e-08	57.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,2QHYI@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Predicted permease YjgP/YjgQ family	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
k59_52317_2	313628.LNTAR_03579	3.64e-09	58.9	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	Z012_04225	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
k59_214755_1	234267.Acid_3820	7.63e-20	95.5	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,3Y6V8@57723|Acidobacteria	57723|Acidobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16
k59_79515_1	1165841.SULAR_06663	7.2e-43	154.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2YMYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_28739_1	2340.JV46_17950	1.31e-101	305.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1J4R1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
k59_96437_1	177437.HRM2_37830	7.28e-52	185.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	acs	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_198162_1	866546.EPY54231	2.94e-05	47.0	COG0567@1|root,KOG0450@2759|Eukaryota,38FJ2@33154|Opisthokonta,3NV83@4751|Fungi,3QNW7@4890|Ascomycota,3MC59@451866|Taphrinomycotina	4751|Fungi	C	2-oxoglutarate dehydrogenase	KGD1	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005947,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0009060,GO:0009295,GO:0009353,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030062,GO:0031974,GO:0032991,GO:0042645,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0051186,GO:0055114,GO:0070013,GO:0071704,GO:0072350,GO:0098798,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_170942_1	909663.KI867150_gene1089	9.77e-114	339.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_204736_1	2340.JV46_06290	2.92e-84	253.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1J6R2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	Z012_09465	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_204736_2	2340.JV46_06300	0.000585	41.2	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1J5GV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_123389_1	1168034.FH5T_08440	2.13e-146	443.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia	976|Bacteroidetes	P	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_48964_1	243233.MCA1459	4.01e-53	179.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XDTH@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_75929_2	1298865.H978DRAFT_2952	1.6e-13	64.7	2C16Q@1|root,330H3@2|Bacteria,1NB82@1224|Proteobacteria,1SERQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
k59_96439_1	1168034.FH5T_12195	2.34e-164	484.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_29080_1	391008.Smal_3630	5.74e-20	95.1	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1X43V@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thiol disulfide Interchange Protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_103482_1	1165841.SULAR_00505	6.91e-88	273.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,42XAR@68525|delta/epsilon subdivisions,2YR2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_191625_1	1304888.ATWF01000001_gene1760	3.22e-53	182.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Cytochrome_CBB3,DUF1566,EF-hand_5,FGE-sulfatase,PD40,Peptidase_S9
k59_15396_1	1165841.SULAR_09009	8.24e-08	52.8	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_15396_2	387093.SUN_0490	2.73e-40	138.0	COG1331@1|root,COG1331@2|Bacteria,1QZ2A@1224|Proteobacteria,43CEH@68525|delta/epsilon subdivisions,2YQRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_164453_1	446462.Amir_4699	8.72e-15	80.9	COG0236@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4DZDB@85010|Pseudonocardiales	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_110300_1	2340.JV46_21960	6.86e-75	249.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_29088_1	387093.SUN_0014	1.17e-122	365.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_76306_1	2340.JV46_27740	7.65e-122	359.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,1JB8I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_69624_1	247634.GPB2148_990	8.22e-43	165.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_69625_1	69328.PVLB_16290	3.14e-29	118.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_123800_1	1168034.FH5T_12800	1.55e-85	254.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_103498_1	1168034.FH5T_21185	1.6e-95	292.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia	976|Bacteroidetes	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
k59_35588_1	41431.PCC8801_0856	4.4e-16	77.0	COG1190@1|root,COG1190@2|Bacteria,1G0SA@1117|Cyanobacteria,3KGUS@43988|Cyanothece	1117|Cyanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.lysS	KTSC,tRNA-synt_2,tRNA_anti-codon
k59_35588_2	1121406.JAEX01000014_gene2339	3.88e-14	76.6	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2M7ZM@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_205130_1	2340.JV46_05440	2.64e-46	169.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1J8EA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_49385_1	998674.ATTE01000001_gene2142	2.84e-166	482.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales	72273|Thiotrichales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_117216_1	1168034.FH5T_05040	2.67e-32	123.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,2FMCR@200643|Bacteroidia	976|Bacteroidetes	S	HD domain protein	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_117216_2	1168034.FH5T_05045	8.22e-62	200.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,2FMZE@200643|Bacteroidia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_1912_1	1380355.JNIJ01000053_gene2150	4.23e-55	191.0	COG0179@1|root,COG1893@1|root,COG0179@2|Bacteria,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2TRJN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C,DUF2437,FAA_hydrolase
k59_198576_1	608538.HTH_1391	3.73e-07	57.0	COG0354@1|root,COG0354@2|Bacteria,2G4QJ@200783|Aquificae	200783|Aquificae	S	Belongs to the GcvT family	-	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
k59_143981_1	757424.Hsero_3525	1.47e-07	59.3	COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,2VQKH@28216|Betaproteobacteria,474VA@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K04033	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
k59_150940_1	1328313.DS2_08068	2.51e-50	183.0	COG0642@1|root,COG0834@1|root,COG4251@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,46DDS@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,SBP_bac_3
k59_164468_2	323261.Noc_0797	1.07e-40	143.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1WX3I@135613|Chromatiales	135613|Chromatiales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_103515_1	2340.JV46_27540	1.5e-103	305.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,1JA91@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_29109_1	313596.RB2501_10187	4.98e-08	52.4	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1HWTZ@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_29109_2	313596.RB2501_10192	1.04e-69	218.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_171340_1	314275.MADE_1008955	1.26e-18	85.9	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,4648Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yhcX	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_1916_1	1165841.SULAR_05723	5.09e-91	270.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_76332_1	1165841.SULAR_05518	1.36e-92	288.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_212023_1	483215.BACFIN_07540	7.42e-36	134.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,2FM4R@200643|Bacteroidia,4AK6N@815|Bacteroidaceae	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_212023_2	1168034.FH5T_11365	4.15e-23	91.7	2AISX@1|root,3199U@2|Bacteria,4NQ7A@976|Bacteroidetes,2FVPS@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49408_1	1165841.SULAR_05463	2.64e-117	340.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,42MPM@68525|delta/epsilon subdivisions,2YMX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_49408_2	1165841.SULAR_05458	1.46e-10	58.5	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2YP8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_29125_1	452637.Oter_2944	2.12e-83	257.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_22208_1	1165841.SULAR_06993	5.88e-111	327.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_22208_2	1165841.SULAR_06988	4.31e-53	177.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_164482_1	195250.CM001776_gene3898	0.000819	47.4	COG3464@1|root,COG3464@2|Bacteria,1G377@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k59_83407_1	985665.HPL003_02340	6.72e-23	98.6	28JEU@1|root,2Z98W@2|Bacteria,1VRU4@1239|Firmicutes,4HTWS@91061|Bacilli,26VIY@186822|Paenibacillaceae	91061|Bacilli	S	PFAM MULE transposase, conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62921_1	1165841.SULAR_09174	5.44e-105	305.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_76341_1	118168.MC7420_4635	7.76e-59	196.0	COG4637@1|root,COG4637@2|Bacteria,1G111@1117|Cyanobacteria,1H8HB@1150|Oscillatoriales	1117|Cyanobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_23
k59_205171_1	13616.ENSMODP00000040418	2.72e-46	165.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,487I3@7711|Chordata,49KYD@7742|Vertebrata,3JPNW@40674|Mammalia	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.3.1.15	ko:K13506	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Exo_endo_phos_2,RVT_1
k59_103547_1	666685.R2APBS1_1464	3.55e-67	215.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1X2ZD@135614|Xanthomonadales	135614|Xanthomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_103547_2	1121015.N789_01590	3.69e-13	68.9	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1X3DY@135614|Xanthomonadales	135614|Xanthomonadales	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_62922_1	749222.Nitsa_0515	1.34e-77	239.0	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,42U7U@68525|delta/epsilon subdivisions,2YN6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
k59_177948_1	1415754.JQMK01000002_gene2809	1.64e-73	247.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria,465X0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_29126_1	1165841.SULAR_02948	2.48e-153	442.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_123823_1	63737.Npun_R2130	3.43e-11	65.1	COG3293@1|root,COG3293@2|Bacteria,1FZVT@1117|Cyanobacteria,1HNVV@1161|Nostocales	1117|Cyanobacteria	L	COGs COG3293 Transposase and inactivated derivatives	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_123823_2	457398.HMPREF0326_05741	5.08e-32	122.0	COG3293@1|root,COG3385@1|root,COG3293@2|Bacteria,COG3385@2|Bacteria,1P5HD@1224|Proteobacteria,42TZG@68525|delta/epsilon subdivisions,2WQT4@28221|Deltaproteobacteria,2MC3W@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_1942_1	156889.Mmc1_3161	2.09e-86	282.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006855,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015238,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015307,GO:0015318,GO:0015672,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902495,GO:1902600,GO:1990281,GO:1990351	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_76343_1	85929.N1QNH3	1.92e-28	122.0	COG0688@1|root,KOG1032@1|root,KOG1032@2759|Eukaryota,KOG2419@2759|Eukaryota,38CUE@33154|Opisthokonta,3NVAR@4751|Fungi,3QMR5@4890|Ascomycota,1ZXGI@147541|Dothideomycetes,3MHGN@451867|Dothideomycetidae	4751|Fungi	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine	PSD2	GO:0000139,GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003674,GO:0003824,GO:0004609,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005773,GO:0005774,GO:0005794,GO:0006575,GO:0006629,GO:0006644,GO:0006646,GO:0006650,GO:0006656,GO:0006658,GO:0006659,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0012505,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0019637,GO:0030447,GO:0031090,GO:0031410,GO:0031667,GO:0031982,GO:0031984,GO:0036170,GO:0036171,GO:0036180,GO:0040007,GO:0042221,GO:0042398,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046337,GO:0046470,GO:0046474,GO:0046486,GO:0050896,GO:0071704,GO:0090407,GO:0097164,GO:0097708,GO:0098588,GO:0098791,GO:0098805,GO:0098852,GO:1901564,GO:1901566,GO:1901576	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	C2,PS_Dcarbxylase
k59_117232_1	261292.Nit79A3_0361	7.05e-93	280.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2WGYA@28216|Betaproteobacteria,374QX@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_117232_2	765912.Thimo_3048	2.79e-35	122.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1WYXS@135613|Chromatiales	135613|Chromatiales	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_205175_1	1121405.dsmv_3107	1.55e-26	108.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MJ5T@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_205175_2	1121405.dsmv_3106	1.92e-14	72.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2MHKY@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_157886_2	1226325.HMPREF1548_01940	6.67e-05	48.9	COG0745@1|root,COG0745@2|Bacteria,1TSCM@1239|Firmicutes,248K7@186801|Clostridia,36FU9@31979|Clostridiaceae	186801|Clostridia	KT	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_58241_2	1165841.SULAR_06678	1.09e-67	208.0	COG2033@1|root,COG2033@2|Bacteria,1Q2YB@1224|Proteobacteria,42WG8@68525|delta/epsilon subdivisions,2YQJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Desulfoferrodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Desulfoferrodox
k59_58241_3	1165841.SULAR_02073	2.07e-96	286.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_18031_1	990073.ATHU01000001_gene917	2.06e-28	117.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_126405_1	1168034.FH5T_11015	8.48e-118	347.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia	976|Bacteroidetes	J	serine--tRNA ligase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_51847_1	870187.Thini_0568	4.78e-45	160.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,45ZPY@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
k59_51847_2	1049564.TevJSym_ad00570	1.22e-54	175.0	COG1633@1|root,COG1633@2|Bacteria,1RDK1@1224|Proteobacteria,1S55F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_166885_1	338963.Pcar_0299	7.46e-26	112.0	COG2202@1|root,COG2203@1|root,COG3920@1|root,COG4936@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3920@2|Bacteria,COG4936@2|Bacteria,COG5002@2|Bacteria,1MVPJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_4,PAS_9,PocR,dCache_2
k59_200876_1	1122201.AUAZ01000006_gene3867	5.31e-22	103.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZS5@1236|Gammaproteobacteria,4676G@72275|Alteromonadaceae	1236|Gammaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,SBP_bac_3
k59_37874_1	1165841.SULAR_00505	1.25e-141	413.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,42XAR@68525|delta/epsilon subdivisions,2YR2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_160367_1	1049564.TevJSym_ae00930	8.45e-132	380.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4CK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_133399_1	5970.XP_009159190.1	4.38e-26	114.0	COG0402@1|root,KOG3968@2759|Eukaryota,38CBX@33154|Opisthokonta,3NU83@4751|Fungi,3QJIV@4890|Ascomycota,20EB8@147545|Eurotiomycetes,3MUQ4@451870|Chaetothyriomycetidae	4751|Fungi	FQ	Guanine deaminase	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_194230_1	1348583.ATLH01000015_gene314	3.76e-05	54.3	COG2911@1|root,COG2911@2|Bacteria,4NS01@976|Bacteroidetes,1I3QG@117743|Flavobacteriia,1F8HT@104264|Cellulophaga	976|Bacteroidetes	M	InterPro IPR003367	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C
k59_166888_1	1131814.JAFO01000001_gene402	1.66e-26	102.0	COG1942@1|root,COG1942@2|Bacteria,1RAXK@1224|Proteobacteria,2U5S6@28211|Alphaproteobacteria,3EZTK@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	4-oxalocrotonate tautomerase	MA20_35940	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_166888_2	358220.C380_22830	1.38e-17	80.5	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,2VQER@28216|Betaproteobacteria,4AEJB@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Glutathione S-transferase domain	gst3	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
k59_92621_1	313596.RB2501_03945	1.29e-24	92.8	2E826@1|root,332G8@2|Bacteria,4NVW3@976|Bacteroidetes,1I54V@117743|Flavobacteriia	976|Bacteroidetes	S	DNA polymerase III subunit alpha	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_92621_2	1185652.USDA257_c05820	3.97e-08	56.6	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,4B9PE@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
k59_160370_1	2340.JV46_25130	1.14e-41	148.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1J5VQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_37876_1	665571.STHERM_c17110	5.41e-111	327.0	COG0214@1|root,COG0214@2|Bacteria,2J5SI@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k59_207838_1	1392838.AWNM01000001_gene1718	3.96e-93	281.0	COG3335@1|root,COG3335@2|Bacteria,1MW8A@1224|Proteobacteria,2W0I7@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k59_92624_2	1297570.MESS4_320073	1.37e-06	48.9	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2UTVN@28211|Alphaproteobacteria,43MAU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_18052_1	187272.Mlg_1400	1.6e-28	111.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1WW4Q@135613|Chromatiales	135613|Chromatiales	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_18052_2	1121033.AUCF01000008_gene5688	7.07e-21	89.4	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,2JRW7@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
k59_37878_1	1165841.SULAR_08377	2.19e-39	137.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2YNGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_37878_2	1165841.SULAR_08372	2.22e-45	152.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2YMH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,NMO
k59_126424_2	981085.XP_010096025.1	1.06e-10	61.2	COG2940@1|root,KOG1082@2759|Eukaryota,37IV0@33090|Viridiplantae,3G9R9@35493|Streptophyta,4JMDI@91835|fabids	35493|Streptophyta	B	histone-lysine N-methyltransferase, H3 lysine-9 specific	-	GO:0000166,GO:0000775,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006325,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008327,GO:0008757,GO:0009987,GO:0010216,GO:0010385,GO:0010428,GO:0010429,GO:0016043,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0034641,GO:0034968,GO:0036094,GO:0036211,GO:0042054,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046974,GO:0051276,GO:0051567,GO:0061647,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0098687,GO:0140096,GO:1901265,GO:1901360,GO:1901363,GO:1901564	2.1.1.43	ko:K11420	ko00310,ko04211,map00310,map04211	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	Pre-SET,SAD_SRA,SET
k59_51864_1	1357714.A0A067XQW4_9CAUD	5.4e-14	80.5	4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses  no RNA stage,4QPYH@28883|Caudovirales,4QIYN@10662|Myoviridae	10662|Myoviridae	S	exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_65383_1	1165841.SULAR_08257	5.8e-42	152.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
k59_65383_2	1165841.SULAR_08262	2.57e-58	192.0	29VY7@1|root,30HGA@2|Bacteria,1Q32U@1224|Proteobacteria,42WPE@68525|delta/epsilon subdivisions,2YQKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_126425_1	3988.XP_002534719.1	1.54e-86	272.0	COG3344@1|root,KOG4768@2759|Eukaryota,37KUX@33090|Viridiplantae,3GHBI@35493|Streptophyta,4JTJX@91835|fabids	35493|Streptophyta	A	NADH dehydrogenase (quinone) activity	matR	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2
k59_194248_1	1168034.FH5T_06725	3.07e-79	237.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,2FSJX@200643|Bacteroidia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_65385_1	1165841.SULAR_02008	6.01e-12	65.5	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2YNPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_65385_2	1165841.SULAR_02003	4.22e-106	331.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,Na_H_Exchanger
k59_146895_1	314265.R2601_19789	1.09e-64	223.0	COG1187@1|root,COG2911@1|root,COG1187@2|Bacteria,COG2911@2|Bacteria,1P8N9@1224|Proteobacteria,2TWRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
k59_126429_1	236097.ADG881_1169	3.02e-40	140.0	COG1216@1|root,COG1216@2|Bacteria,1N6DH@1224|Proteobacteria,1T31U@1236|Gammaproteobacteria,1XRSX@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_126429_2	1173024.KI912149_gene6090	4.33e-46	158.0	COG0562@1|root,COG0562@2|Bacteria,1GBR1@1117|Cyanobacteria,1JJYM@1189|Stigonemataceae	1117|Cyanobacteria	M	UDP-galactopyranose mutase	-	-	-	-	-	-	-	-	-	-	-	-	GLF,NAD_binding_8
k59_44876_1	998674.ATTE01000001_gene4560	4.47e-88	276.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,1RPFC@1236|Gammaproteobacteria,463KS@72273|Thiotrichales	72273|Thiotrichales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_200893_1	397945.Aave_3359	1.78e-67	225.0	COG0286@1|root,COG5502@1|root,COG0286@2|Bacteria,COG5502@2|Bacteria,1MW3A@1224|Proteobacteria,2VK6V@28216|Betaproteobacteria,4ABV9@80864|Comamonadaceae	28216|Betaproteobacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_72113_1	1165841.SULAR_08242	3.25e-235	664.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_78907_1	1131553.JIBI01000039_gene1941	7.47e-31	119.0	COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,2VNRP@28216|Betaproteobacteria,372MR@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,DUF2934,OSCP
k59_78907_2	1288826.MSNKSG1_00536	2.3e-38	129.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_153578_1	1492737.FEM08_33520	2.82e-09	56.6	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia,2NTHK@237|Flavobacterium	976|Bacteroidetes	O	Molecular chaperone, HSP90	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_153578_2	313596.RB2501_01915	5.08e-40	140.0	28HM7@1|root,2Z7VU@2|Bacteria,4NGV1@976|Bacteroidetes,1HXYU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_58703_1	1165841.SULAR_09904	2.7e-84	260.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_133426_2	156889.Mmc1_2664	9.78e-32	115.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,2U7MB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_133426_3	1121937.AUHJ01000066_gene16	7.5e-23	97.8	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,4655T@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_180454_1	1442599.JAAN01000031_gene1423	2.17e-23	94.7	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,1X76E@135614|Xanthomonadales	135614|Xanthomonadales	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
k59_180454_2	1123261.AXDW01000024_gene2078	0.000404	42.4	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1X3C3@135614|Xanthomonadales	135614|Xanthomonadales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_194261_1	493475.GARC_4142	6.81e-15	71.6	2E37U@1|root,32Y7H@2|Bacteria,1N8JQ@1224|Proteobacteria,1SCAH@1236|Gammaproteobacteria,468V8@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2956
k59_51882_1	1168034.FH5T_01575	1.63e-45	160.0	COG1520@1|root,COG1520@2|Bacteria,4P15Y@976|Bacteroidetes,2FWBU@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2
k59_51882_2	1267211.KI669560_gene634	3.81e-36	132.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1IS2R@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
k59_85912_1	502025.Hoch_1723	2.93e-30	123.0	COG4870@1|root,COG4870@2|Bacteria,1Q2ZQ@1224|Proteobacteria,438PA@68525|delta/epsilon subdivisions,2X3X1@28221|Deltaproteobacteria,2YXEN@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase C1 family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166924_1	2340.JV46_06580	1.32e-101	307.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1J895@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_153589_1	682795.AciX8_0788	2.31e-92	302.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_146919_1	331869.BAL199_29100	1.03e-15	78.6	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
k59_4656_1	1165841.SULAR_02668	2.44e-111	327.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_112514_1	90814.KL370892_gene2147	1.69e-46	160.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,460ST@72273|Thiotrichales	72273|Thiotrichales	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_65417_1	1123400.KB904746_gene1191	7.69e-19	87.4	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,46223@72273|Thiotrichales	72273|Thiotrichales	V	involved in Fe-S cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_65417_2	2340.JV46_11240	6.06e-60	187.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,1T20V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
k59_126459_1	1110502.TMO_2573	5.96e-64	218.0	COG0119@1|root,COG4770@1|root,COG0119@2|Bacteria,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2JPR7@204441|Rhodospirillales	204441|Rhodospirillales	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_126459_2	1184267.A11Q_2274	2.31e-57	193.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,42N6D@68525|delta/epsilon subdivisions,2MSQI@213481|Bdellovibrionales,2X5IJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	carboxylase	mccB	-	6.4.1.4,6.4.1.5	ko:K01969,ko:K13778	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R03494,R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3290	Carboxyl_trans
k59_31635_1	1442598.JABW01000012_gene395	7.51e-71	234.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,43DHS@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_34782_1	1169161.KB897725_gene1740	3.43e-28	109.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k59_34782_2	760568.Desku_0008	4.78e-30	113.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,261H3@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
k59_211109_1	1165841.SULAR_01718	7.55e-12	70.5	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1N68I@1224|Proteobacteria,43BAI@68525|delta/epsilon subdivisions,2YT7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_143267_1	1165841.SULAR_09049	3.4e-30	109.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2YPGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	fur	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_143267_2	1165841.SULAR_09044	3.73e-101	298.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42Y2B@68525|delta/epsilon subdivisions,2YT6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane protein, required for colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_143267_3	1165841.SULAR_09039	3.64e-27	107.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_89162_1	1168034.FH5T_08830	1.35e-84	256.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,2FM5W@200643|Bacteroidia	976|Bacteroidetes	Q	ABC transporter, ATP-binding protein	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_34787_1	102232.GLO73106DRAFT_00004350	1.8e-08	60.8	COG3210@1|root,COG3210@2|Bacteria,1G0EK@1117|Cyanobacteria	1117|Cyanobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
k59_197565_1	177437.HRM2_17050	5.48e-71	223.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria,2MIFR@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ATP_bind_3
k59_75436_1	1165841.SULAR_07645	3.36e-63	207.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,42P2P@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	phosphotransferase system, EIIB	nagE	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0015764,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0090563,GO:0090586,GO:1901264	2.7.1.193	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	iECP_1309.ECP_0691	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k59_109354_1	316067.Geob_3224	1.25e-33	132.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,42V8Q@68525|delta/epsilon subdivisions,2WRSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k59_143272_1	1353276.JADR01000006_gene1166	4.39e-15	80.1	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes,1HZ8C@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
k59_163624_1	118173.KB235914_gene3164	1.21e-69	225.0	COG0033@1|root,COG0033@2|Bacteria,1G0ZB@1117|Cyanobacteria,1H9DN@1150|Oscillatoriales	1117|Cyanobacteria	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_21270_2	1121405.dsmv_2725	1.26e-53	181.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2WM7G@28221|Deltaproteobacteria,2MJ9U@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	PFAM nucleoside H symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_89171_1	395493.BegalDRAFT_2574	5.17e-68	233.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,46043@72273|Thiotrichales	1236|Gammaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_177100_1	4081.Solyc00g052430.2.1	2.81e-102	306.0	COG2801@1|root,KOG0017@2759|Eukaryota,37TAQ@33090|Viridiplantae,3GDDG@35493|Streptophyta	35493|Streptophyta	L	cellular component organization	ccmFc	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	CcmF_C
k59_150091_1	756272.Plabr_1440	1.09e-59	192.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C
k59_82317_1	1165841.SULAR_01868	5.67e-32	114.0	COG2138@1|root,COG2138@2|Bacteria,1PRX7@1224|Proteobacteria,42VX1@68525|delta/epsilon subdivisions,2YSGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cobalt chelatase (CbiK)	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
k59_82317_2	1165841.SULAR_01863	1.02e-60	190.0	COG3040@1|root,COG3040@2|Bacteria,1PSJU@1224|Proteobacteria,42VH5@68525|delta/epsilon subdivisions,2YQC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
k59_7613_1	1278307.KB906975_gene1888	1.28e-35	125.0	COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,2QHY5@267894|Psychromonadaceae	1236|Gammaproteobacteria	J	Elongation factor P (EF-P) OB domain	yeiP	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_7613_2	1049564.TevJSym_aa02450	2.72e-24	102.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,1RSFG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k59_197580_1	391587.KAOT1_06397	7.33e-11	61.2	COG0028@1|root,COG0028@2|Bacteria,4NINQ@976|Bacteroidetes,1HXH8@117743|Flavobacteriia	976|Bacteroidetes	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_197580_2	1165841.SULAR_06683	4.47e-53	169.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,42VPQ@68525|delta/epsilon subdivisions,2YRZA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_934_1	557598.LHK_02764	1.7e-25	108.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,2KPGD@206351|Neisseriales	206351|Neisseriales	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_89185_1	387093.SUN_0406	1.46e-48	163.0	COG4461@1|root,COG4461@2|Bacteria,1PFFH@1224|Proteobacteria,43ABM@68525|delta/epsilon subdivisions,2YR0C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
k59_183908_2	1217705.F900_01118	4.12e-07	52.0	COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S5B3@1236|Gammaproteobacteria,3NNHQ@468|Moraxellaceae	1236|Gammaproteobacteria	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
k59_143285_1	340177.Cag_1600	1.17e-24	102.0	COG3950@1|root,COG3950@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
k59_143285_2	56110.Oscil6304_1093	2.11e-66	217.0	COG0732@1|root,COG0732@2|Bacteria,1G796@1117|Cyanobacteria,1HBPS@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_109371_1	395493.BegalDRAFT_2585	1.9e-72	237.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,CHAT,GerE,NB-ARC,TPR_10,TPR_12
k59_21275_1	3827.XP_004516189.1	0.0	1118.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,4JSMX@91835|fabids	35493|Streptophyta	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_129686_1	2340.JV46_17420	3.27e-39	137.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1J4Q3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
k59_129686_2	290398.Csal_3286	8.62e-26	106.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XHRG@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_116210_1	246197.MXAN_3461	1.14e-52	183.0	COG0236@1|root,COG1028@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,42KZK@68525|delta/epsilon subdivisions,2X25T@28221|Deltaproteobacteria,2YX97@29|Myxococcales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	fabG9	-	-	-	-	-	-	-	-	-	-	-	PP-binding,adh_short_C2
k59_68734_1	1123399.AQVE01000006_gene3555	6.22e-26	105.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K19661	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,Response_reg
k59_68734_2	1123399.AQVE01000006_gene3556	7.35e-25	101.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RMPB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase-like, 20kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_156839_1	1198232.CYCME_0822	1.45e-80	247.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_21279_1	1298867.AUES01000035_gene2166	1.11e-24	102.0	COG2020@1|root,COG2020@2|Bacteria,1RDC4@1224|Proteobacteria,2TUXA@28211|Alphaproteobacteria,3JU1Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_183916_1	1165841.SULAR_08482	3.85e-98	297.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_122935_1	1217710.F969_03677	3.37e-35	132.0	COG3039@1|root,COG3039@2|Bacteria,1MXP1@1224|Proteobacteria,1RSBM@1236|Gammaproteobacteria,3NIY5@468|Moraxellaceae	1236|Gammaproteobacteria	L	There are 9 addittional ORFs identical to this one	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
k59_136468_1	998088.B565_2943	7.58e-47	159.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1Y40H@135624|Aeromonadales	135624|Aeromonadales	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_82341_1	243233.MCA3071	2.33e-63	205.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,1T1N6@1236|Gammaproteobacteria,1XEN9@135618|Methylococcales	135618|Methylococcales	C	PFAM Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_957_2	65393.PCC7424_5877	2.38e-34	128.0	COG3335@1|root,COG3335@2|Bacteria,1G06Q@1117|Cyanobacteria,3KKQ2@43988|Cyanothece	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_Tnp_IS630
k59_143295_1	395493.BegalDRAFT_2618	1.06e-67	210.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,45ZXA@72273|Thiotrichales	72273|Thiotrichales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_143295_2	983545.Glaag_0545	1.98e-23	92.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,467D4@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_95826_1	1121923.GPUN_1571	8.62e-14	75.5	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,464D7@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_61956_1	1121937.AUHJ01000001_gene758	5.71e-39	145.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_61956_2	247634.GPB2148_3202	1.52e-59	196.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1J565@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	zinc metalloprotease	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_75463_1	1168034.FH5T_05140	2.8e-59	189.0	COG4912@1|root,COG4912@2|Bacteria,4NUAZ@976|Bacteroidetes,2FQ8F@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_183924_1	1128421.JAGA01000002_gene1117	1.26e-29	122.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	gumK	-	2.4.1.264	ko:K07011,ko:K13659	-	-	R09732	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT70	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
k59_190843_1	566466.NOR53_675	1.76e-37	132.0	COG1416@1|root,COG1416@2|Bacteria,1NP3E@1224|Proteobacteria	1224|Proteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_1234_1	746697.Aeqsu_3121	9.54e-17	85.1	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1HYJU@117743|Flavobacteriia	976|Bacteroidetes	L	Restriction	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
k59_68933_2	4577.GRMZM5G815453_P01	0.0	875.0	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta,3KWKY@4447|Liliopsida,3ICQI@38820|Poales	35493|Streptophyta	G	Ribulose bisphosphate carboxylase large chain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_177361_1	870187.Thini_4337	3.06e-30	115.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,1RNM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	4.2.1.113,4.2.1.171	ko:K02549,ko:K21624	ko00130,ko00330,ko01100,ko01110,map00130,map00330,map01100,map01110	M00116	R04031,R11625	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k59_1241_2	3712.Bo00984s040.1	6.67e-06	48.9	29IBG@1|root,2RRIT@2759|Eukaryota,385CA@33090|Viridiplantae,3GQVJ@35493|Streptophyta	35493|Streptophyta	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
k59_1241_3	71139.XP_010042046.1	1.43e-07	52.8	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta	35493|Streptophyta	L	DNA RNA polymerases superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Chromo,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_85854_1	1165841.SULAR_00175	4.75e-43	146.0	COG1566@1|root,COG1566@2|Bacteria,1QYCU@1224|Proteobacteria,42TB0@68525|delta/epsilon subdivisions,2YPDT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k59_173651_1	631362.Thi970DRAFT_03839	1.19e-78	243.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,1WYUF@135613|Chromatiales	135613|Chromatiales	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
k59_207804_1	1396858.Q666_08260	1.81e-100	301.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,466DK@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG1793 ATP-dependent DNA ligase	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k59_153518_1	1298880.AUEV01000006_gene4237	1.18e-34	131.0	COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,2IAU4@201174|Actinobacteria	201174|Actinobacteria	M	methyltransferase	-	-	2.1.1.156,2.1.1.157	ko:K18896,ko:K18897	ko00260,map00260	-	R10060,R10061	RC00003,RC03038,RC03040	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
k59_153518_2	582515.KR51_00033120	6.46e-39	136.0	COG0500@1|root,COG2226@2|Bacteria,1G3XX@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family	gsmt	GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0017174,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052730,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.1.1.156	ko:K18896	ko00260,map00260	-	R10060	RC00003,RC03038	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25
k59_31559_1	1189620.AJXL01000240_gene1528	2.82e-17	73.2	arCOG05874@1|root,2ZJ01@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85858_1	7425.NV19168-PA	1.86e-28	118.0	2CN0N@1|root,2QT5H@2759|Eukaryota,38HD6@33154|Opisthokonta,3BNTW@33208|Metazoa,3D1YD@33213|Bilateria,41XP3@6656|Arthropoda	33208|Metazoa	S	nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2,Endonuclease_7
k59_92571_2	555778.Hneap_1232	2.24e-24	100.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1WWN2@135613|Chromatiales	135613|Chromatiales	O	PFAM peptidase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_200858_1	251221.35211057	1.14e-36	135.0	COG4798@1|root,COG4798@2|Bacteria,1GCU2@1117|Cyanobacteria	1117|Cyanobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146851_1	998674.ATTE01000001_gene4336	1.09e-81	256.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,45ZPY@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_85861_1	313596.RB2501_02380	7.7e-112	345.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_146853_1	1165841.SULAR_07405	1.31e-106	311.0	COG2426@1|root,COG2426@2|Bacteria,1N9Q5@1224|Proteobacteria,43BIM@68525|delta/epsilon subdivisions,2YS5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
k59_92576_1	398580.Dshi_1709	2.06e-40	149.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2U3WC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
k59_72060_1	1340434.AXVA01000011_gene3242	6.79e-67	225.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,4HCVY@91061|Bacilli,1ZBTS@1386|Bacillus	91061|Bacilli	C	COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, alpha subunit	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
k59_99461_1	2340.JV46_13300	4.98e-173	517.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J582@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_18001_1	7260.FBpp0248828	0.000519	50.8	COG0318@1|root,COG1131@1|root,KOG0059@2759|Eukaryota,KOG1176@2759|Eukaryota,38D90@33154|Opisthokonta,3BIS4@33208|Metazoa,3CTVC@33213|Bilateria,41U94@6656|Arthropoda,3SHQB@50557|Insecta,44Y9J@7147|Diptera,45WAB@7214|Drosophilidae	33208|Metazoa	I	activity. It is involved in the biological process described with metabolic process	-	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0015645,GO:0016053,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_187234_1	82654.Pse7367_0728	1.93e-100	300.0	COG2326@1|root,COG2326@2|Bacteria,1G34U@1117|Cyanobacteria,1H708@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_31569_1	1121448.DGI_2662	4.25e-95	311.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
k59_99464_2	317025.Tcr_0486	2.1e-56	178.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,460QK@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_92584_2	4081.Solyc00g014830.2.1	3.27e-73	229.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase (Ubiquinone) iron-sulfur protein	nad7	-	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k59_4571_1	2340.JV46_15470	1.28e-69	210.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1J6P0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	part of a sulfur-relay system	tusE	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_4571_2	2340.JV46_15480	9.55e-34	118.0	COG2168@1|root,COG2168@2|Bacteria	2|Bacteria	P	tRNA wobble position uridine thiolation	tusB	GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
k59_153536_1	1229780.BN381_380002	4.69e-14	73.2	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k59_160350_1	313596.RB2501_09370	7.63e-67	214.0	COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes,1HXP5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_173672_1	686578.AFFX01000003_gene179	1.03e-12	67.8	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_173672_2	1033802.SSPSH_002815	4.97e-81	247.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
k59_4573_1	395493.BegalDRAFT_2969	5.57e-64	222.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_133375_2	1165841.SULAR_03522	2.54e-55	176.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_194210_2	491952.Mar181_2412	4.77e-27	106.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,1S6SU@1236|Gammaproteobacteria,1XS89@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
k59_207820_1	1115512.EH105704_02_05190	5.82e-57	190.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,3XMG0@561|Escherichia	1236|Gammaproteobacteria	M	Lytic murein transglycosylase B	mltB	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031402,GO:0031420,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044462,GO:0044464,GO:0046872,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	iECABU_c1320.ECABU_c29710,iNRG857_1313.NRG857_13215	SLT_2
k59_78872_2	313598.MED152_02130	5.04e-20	86.7	2A263@1|root,30QGN@2|Bacteria,4NMYV@976|Bacteroidetes,1I29B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_99473_1	385682.AFSL01000034_gene2983	2.83e-47	152.0	COG2963@1|root,COG2963@2|Bacteria,4NSUA@976|Bacteroidetes,2G29G@200643|Bacteroidia,3XKFP@558415|Marinilabiliaceae	976|Bacteroidetes	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_207822_1	33169.AAS53625	3.19e-08	53.9	COG0151@1|root,KOG0237@2759|Eukaryota,38BPB@33154|Opisthokonta,3NXWQ@4751|Fungi,3QPMK@4890|Ascomycota,3RRBW@4891|Saccharomycetes,3S0NH@4893|Saccharomycetaceae	4751|Fungi	F	to Saccharomyces cerevisiae ADE5,7 (YGL234W)	-	GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1,6.3.4.13	ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YGL234W,iND750.YGL234W	AIRS,AIRS_C,GARS_A,GARS_C,GARS_N
k59_207822_2	313596.RB2501_06655	2.89e-76	236.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_37866_1	177437.HRM2_03750	1.77e-60	206.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,42NX3@68525|delta/epsilon subdivisions,2WME4@28221|Deltaproteobacteria,2MPJH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_37866_2	1129374.AJE_09419	1.78e-23	93.2	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,46851@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_85875_1	387093.SUN_2211	2.02e-19	89.0	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions	1224|Proteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_85875_2	387093.SUN_2210	2.1e-104	305.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2YNWA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0321	Guanylate_kin
k59_173679_1	1198232.CYCME_1854	2.48e-26	106.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,460SY@72273|Thiotrichales	72273|Thiotrichales	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_173679_2	2340.JV46_18820	9.31e-132	380.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1J4MQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k59_106249_2	3880.AES58577	3.54e-90	292.0	COG0056@1|root,COG0356@1|root,COG1622@1|root,KOG1353@2759|Eukaryota,KOG4665@2759|Eukaryota,KOG4767@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta,4JSJY@91835|fabids	35493|Streptophyta	C	ATP synthase	atp1	-	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,COX2_TM
k59_126402_1	1165841.SULAR_01838	5.61e-35	127.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2YM84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k59_126402_2	1165841.SULAR_01843	2.58e-47	155.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,42U84@68525|delta/epsilon subdivisions,2YPVG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_153548_1	1125863.JAFN01000001_gene1311	1.36e-88	271.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,42PDK@68525|delta/epsilon subdivisions,2WJKJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
k59_160359_3	1123269.NX02_20130	3.41e-14	75.5	2ERQK@1|root,33J9W@2|Bacteria,1NQEB@1224|Proteobacteria,2UWBQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_51845_1	637905.SVI_1055	2.2e-32	125.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,2Q8GP@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	mscS	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_146872_1	270374.MELB17_01135	1.26e-129	377.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,465E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_31923_2	1286106.MPL1_05664	7.65e-55	179.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,460HI@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_160749_1	313628.LNTAR_18278	1.07e-05	53.1	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
k59_65806_1	589865.DaAHT2_0587	7.32e-54	192.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,2MN6Y@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_106735_1	1121918.ARWE01000001_gene216	1.44e-09	65.9	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,43RYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RadC,ResIII
k59_52172_2	1340434.AXVA01000019_gene973	5.46e-14	71.2	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,1ZQA5@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
k59_52172_3	1121939.L861_00175	0.0004	43.1	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_8,PAS_9,Response_reg
k59_214584_1	1410628.JNKS01000013_gene471	1.42e-15	81.6	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,27JID@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
k59_174112_2	1150600.ADIARSV_2193	2.26e-19	90.1	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IVQ5@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
k59_52176_1	244582.JQAK01000002_gene577	4.36e-39	143.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U0BU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_120183_1	1165841.SULAR_02483	1.44e-88	267.0	2DN4A@1|root,32VFK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194672_2	765913.ThidrDRAFT_1746	1.08e-37	128.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1WZA0@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_194672_3	2340.JV46_07290	2.05e-23	90.5	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1J6WB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_174117_1	472759.Nhal_3824	9.68e-27	110.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales	135613|Chromatiales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_174117_2	424716.B1GS51_9CAUD	1.99e-25	98.6	4QAU9@10239|Viruses,4QVR2@35237|dsDNA viruses  no RNA stage,4QQV4@28883|Caudovirales,4QKUJ@10699|Siphoviridae	10699|Siphoviridae	S	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174123_1	1216007.AOPM01000032_gene3407	0.00013	46.6	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1TDYI@1236|Gammaproteobacteria,2Q1I1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	Outer membrane receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_174123_2	491952.Mar181_3516	1.09e-22	97.1	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales	135619|Oceanospirillales	L	Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_54979_1	1379270.AUXF01000001_gene1944	5.91e-64	219.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
k59_170152_1	545276.KB898729_gene1622	2.21e-16	79.3	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1WWQF@135613|Chromatiales	135613|Chromatiales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_170152_2	2340.JV46_17110	1.37e-44	156.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1J5VI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_163433_1	709986.Deima_2038	3.24e-116	354.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1WIBM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	bhbA	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_21136_1	1249480.B649_03965	5.37e-97	313.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_143048_1	1227261.HMPREF0043_00005	1.29e-14	75.9	COG0314@1|root,COG0521@1|root,COG0314@2|Bacteria,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4D4NU@85005|Actinomycetales	201174|Actinobacteria	H	Molybdenum cofactor synthesis	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoaE
k59_143048_2	529818.AMSG_06447T0	1.67e-38	142.0	COG0143@1|root,KOG1247@2759|Eukaryota,KOG2241@2759|Eukaryota	2759|Eukaryota	J	tRNA binding	MES1	GO:0002181,GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10,6.1.1.6	ko:K01874,ko:K04567	ko00450,ko00970,map00450,map00970	M00359,M00360	R03658,R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,MetRS-N,WHEP-TRS,tRNA-synt_1g,tRNA_bind
k59_54987_1	765911.Thivi_2664	2.33e-66	216.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria,1SHHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
k59_163444_1	667632.KB890165_gene2592	5.82e-19	87.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VRGJ@28216|Betaproteobacteria,1K0H4@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_88922_1	1121405.dsmv_2856	2.22e-42	156.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_197347_1	1168289.AJKI01000002_gene2510	3.56e-12	67.0	COG2849@1|root,COG2849@2|Bacteria,4NUDS@976|Bacteroidetes,2FTTJ@200643|Bacteroidia,3XK3X@558415|Marinilabiliaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
k59_7436_2	981383.AEWH01000050_gene116	4.02e-15	75.1	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHGJ@91061|Bacilli	91061|Bacilli	T	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_744_1	2340.JV46_14510	1.25e-90	279.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1J50Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0019438,GO:0019464,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_210916_1	1168034.FH5T_19750	2.64e-39	145.0	COG0527@1|root,COG0527@2|Bacteria,4PKFA@976|Bacteroidetes,2G3F2@200643|Bacteroidia	976|Bacteroidetes	E	Amino acid kinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_68565_1	1168034.FH5T_12600	1.22e-64	213.0	COG3266@1|root,COG3266@2|Bacteria,4NH1U@976|Bacteroidetes,2FUGU@200643|Bacteroidia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_21148_1	234831.PSM_A0470	6.35e-36	125.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,2Q4NZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_88936_2	1042377.AFPJ01000037_gene2984	1.94e-20	91.3	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,464IU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Mannosyl-3-phosphoglycerate phosphatase	yedP	-	2.7.1.31,3.1.3.70	ko:K07026,ko:K15918	ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200	M00532	R01514,R05790	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3,S6PP
k59_149870_1	63737.Npun_R0250	4.93e-29	112.0	COG0835@1|root,COG0835@2|Bacteria,1G6T8@1117|Cyanobacteria,1HSCG@1161|Nostocales	1117|Cyanobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K13488	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
k59_14342_1	1165841.SULAR_06728	4.52e-44	144.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_197357_1	1165841.SULAR_03782	2.9e-95	300.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_82134_1	1041139.KB902702_gene2563	7.52e-27	116.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_19
k59_48204_1	1168289.AJKI01000031_gene1072	1.83e-54	182.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,3XJIK@558415|Marinilabiliaceae	976|Bacteroidetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_163467_1	1165841.SULAR_00675	2.83e-78	238.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MUK@68525|delta/epsilon subdivisions,2YNN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ABC transporter superfamily	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00190,M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
k59_163467_2	1165841.SULAR_00670	1.31e-24	97.8	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2YN88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_129486_2	402881.Plav_0223	4.63e-51	176.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,1JMZH@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_143068_2	1528106.JRJE01000008_gene1485	2.03e-39	145.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2JR4A@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
k59_775_2	756272.Plabr_1285	2.25e-25	107.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
k59_95627_1	261292.Nit79A3_3091	1.26e-30	118.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2WGFK@28216|Betaproteobacteria,372XY@32003|Nitrosomonadales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_14363_1	1165841.SULAR_03517	8.08e-56	178.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,433JY@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_14363_2	1165841.SULAR_03562	1.34e-34	120.0	COG1550@1|root,COG1550@2|Bacteria,1Q2MJ@1224|Proteobacteria,42VYB@68525|delta/epsilon subdivisions,2YQ9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k59_27919_1	2340.JV46_04780	1.61e-72	230.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_149883_1	387093.SUN_1885	4.63e-88	263.0	COG1376@1|root,COG1376@2|Bacteria,1Q44E@1224|Proteobacteria,42Y80@68525|delta/epsilon subdivisions,2YR1Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_183731_1	388413.ALPR1_21088	1.33e-39	150.0	COG1361@1|root,COG3210@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11
k59_34697_1	1358423.N180_20780	1.41e-09	57.8	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_34697_2	1249997.JHZW01000003_gene3643	3.62e-28	102.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1I50J@117743|Flavobacteriia,2PHNE@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_197804_1	857087.Metme_1124	1.1e-39	150.0	COG0515@1|root,COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
k59_1185_1	1121405.dsmv_0504	4.68e-72	232.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N5C@68525|delta/epsilon subdivisions,2WM18@28221|Deltaproteobacteria,2MIV1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_68895_1	1336803.PHEL49_1433	3.28e-45	159.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia,3VV30@52959|Polaribacter	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_68895_2	313596.RB2501_16014	9.84e-29	111.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1HWJN@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
k59_34999_1	1165841.SULAR_01743	4.07e-81	251.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_197807_1	2340.JV46_25970	4.52e-120	350.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1J7FX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_48654_1	391615.ABSJ01000005_gene600	3.52e-93	281.0	COG0225@1|root,COG2143@1|root,COG0225@2|Bacteria,COG2143@2|Bacteria,1MVUS@1224|Proteobacteria,1T0T1@1236|Gammaproteobacteria,1JBSC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR,Thioredoxin_2
k59_177317_1	156889.Mmc1_1609	2.45e-91	277.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2U2RA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_136685_1	546274.EIKCOROL_01800	1.5e-29	111.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KR3W@206351|Neisseriales	206351|Neisseriales	S	Macro domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_136685_2	768671.ThimaDRAFT_1391	3.9e-48	158.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1WY5Q@135613|Chromatiales	135613|Chromatiales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_14793_1	1165841.SULAR_07885	5.17e-56	174.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2YPSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Nitrogen fixation protein NifU	-	-	-	-	-	-	-	-	-	-	-	-	NifU
k59_14793_2	387093.SUN_2286	2.43e-24	96.3	2AJZN@1|root,31ANZ@2|Bacteria,1Q5WH@1224|Proteobacteria,42UJ4@68525|delta/epsilon subdivisions,2YPXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_116504_1	1112209.AHVZ01000011_gene249	5.64e-13	70.1	COG2204@1|root,COG2204@2|Bacteria,1QXZY@1224|Proteobacteria,1T3KW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_55431_1	203119.Cthe_1722	3.27e-13	74.3	COG1372@1|root,COG4626@1|root,COG1372@2|Bacteria,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,3WHWB@541000|Ruminococcaceae	186801|Clostridia	L	large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
k59_177327_1	1165841.SULAR_09144	1.64e-82	254.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_177327_2	1165841.SULAR_09149	4.07e-52	167.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,42RGH@68525|delta/epsilon subdivisions,2YP5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_21492_1	2340.JV46_06670	8.27e-130	382.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1J4NG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_21492_2	1116472.MGMO_86c00110	2.38e-09	58.5	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XE8E@135618|Methylococcales	135618|Methylococcales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_211441_1	56107.Cylst_0785	2.58e-39	149.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,PilZ
k59_177333_1	285514.JNWO01000019_gene7511	1.33e-60	201.0	COG0686@1|root,COG0686@2|Bacteria,2GKMN@201174|Actinobacteria	201174|Actinobacteria	E	alanine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_35015_1	1165841.SULAR_10369	6.57e-75	249.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_35015_2	1165841.SULAR_10364	1.38e-118	374.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_150294_1	1165841.SULAR_00545	1.7e-102	303.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_184141_2	243233.MCA1962	2.33e-17	79.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1XE9E@135618|Methylococcales	135618|Methylococcales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_109644_1	1168034.FH5T_08840	3.22e-17	79.7	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,2FNHF@200643|Bacteroidia	976|Bacteroidetes	M	Mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_85545_1	876044.IMCC3088_2206	2.54e-79	245.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_99226_1	247490.KSU1_C1159	2.97e-10	62.0	COG2733@1|root,COG2733@2|Bacteria,2J2DM@203682|Planctomycetes	203682|Planctomycetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_37600_1	2340.JV46_06610	3.53e-88	276.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_64972_1	84531.JMTZ01000044_gene965	7e-69	221.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1X9GG@135614|Xanthomonadales	135614|Xanthomonadales	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_133013_1	1165841.SULAR_03762	2.38e-154	445.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_31220_2	1249627.D779_1739	9.57e-67	203.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S765@1236|Gammaproteobacteria,1WYIN@135613|Chromatiales	135613|Chromatiales	C	PFAM Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
k59_31220_3	1485544.JQKP01000008_gene1763	3.68e-10	59.3	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,44W9J@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_213987_2	1049564.TevJSym_be00350	1.68e-55	180.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1J59F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07660	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_24331_1	537013.CLOSTMETH_00712	1.16e-22	97.1	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3WG9T@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_146537_1	991.IW20_05235	6.75e-14	69.7	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia,2NTNF@237|Flavobacterium	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_146537_2	313596.RB2501_09980	1.14e-125	359.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1HWWF@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_10718_1	1121875.KB907546_gene2720	2.33e-120	364.0	28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes,1I89H@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_17662_2	1538644.KO02_05430	2.87e-59	202.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_37604_1	1121015.N789_06345	4.27e-59	209.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_44493_1	1169143.KB911041_gene636	3.7e-33	119.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1JZT7@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Acetolactate synthase, small subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_85557_1	1500890.JQNL01000001_gene1507	2.55e-51	165.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1X64V@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_44494_1	1122599.AUGR01000006_gene3887	1.13e-13	70.1	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1XJ6T@135619|Oceanospirillales	135619|Oceanospirillales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_44494_2	1121033.AUCF01000008_gene5736	1.26e-44	155.0	COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,2TR3K@28211|Alphaproteobacteria,2JSKX@204441|Rhodospirillales	204441|Rhodospirillales	M	Penicillin-insensitive murein endopeptidase	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
k59_186960_3	339670.Bamb_1333	2.58e-07	54.3	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VP1R@28216|Betaproteobacteria,1K48K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_119535_1	640081.Dsui_3012	1.07e-53	181.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria,2KV18@206389|Rhodocyclales	206389|Rhodocyclales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_207530_1	118173.KB235914_gene2641	1.35e-12	70.1	2C3WA@1|root,2Z8P1@2|Bacteria,1G958@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166604_1	1121085.AUCI01000010_gene423	0.000434	44.3	COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,1ZGY4@1386|Bacillus	91061|Bacilli	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_17669_1	1384054.N790_14915	2.3e-30	112.0	COG3682@1|root,COG3682@2|Bacteria,1PWS8@1224|Proteobacteria,1RU6Q@1236|Gammaproteobacteria,1X8DM@135614|Xanthomonadales	135614|Xanthomonadales	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_17669_2	379066.GAU_0801	1.21e-07	59.7	COG1413@1|root,COG4219@1|root,COG1413@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Peptidase_M56
k59_105904_1	1538644.KO02_00665	5.64e-06	48.5	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IP7Q@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_S41,Tricorn_C1
k59_85563_1	78398.KS43_07485	7.02e-37	137.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1MR77@122277|Pectobacterium	1236|Gammaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	iSDY_1059.SDY_4251	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_92293_1	2340.JV46_18360	1.81e-50	166.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1J54R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
k59_92293_2	1396858.Q666_09165	2.5e-30	115.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,466DX@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECO111_1330.ECO111_2936,iYL1228.KPN_02080	CcmB
k59_44500_1	1168034.FH5T_11720	7.18e-56	185.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,2FKYE@200643|Bacteroidia	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
k59_105909_1	1121937.AUHJ01000001_gene567	8.72e-15	75.5	29Y8Z@1|root,30K2R@2|Bacteria,1Q11V@1224|Proteobacteria,1SW6B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ
k59_105909_2	1125973.JNLC01000004_gene3121	2.3e-07	51.2	COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,2UA0Y@28211|Alphaproteobacteria,3JW6Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	hupE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03192	-	-	-	-	ko00000	-	-	-	HupE_UreJ
k59_214004_1	639030.JHVA01000001_gene1491	9.73e-20	88.2	COG3247@1|root,COG3247@2|Bacteria,3Y5AN@57723|Acidobacteria,2JJYZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
k59_17676_1	1122212.AULO01000006_gene1844	5.35e-36	132.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1XH7T@135619|Oceanospirillales	135619|Oceanospirillales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_17676_2	319224.Sputcn32_1957	4e-08	51.2	COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,2QCSE@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM Cbb3-type cytochrome oxidase component	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_133458_3	1165841.SULAR_01873	2.03e-61	192.0	COG1853@1|root,COG1853@2|Bacteria,1RAIQ@1224|Proteobacteria,42QXX@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Flavin reductase like domain	flr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_173724_1	1165841.SULAR_09864	3.57e-86	264.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_214269_1	1000565.METUNv1_02818	1.64e-52	182.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,2KVHB@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_153609_1	1168034.FH5T_07865	1.42e-68	209.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,2FYF3@200643|Bacteroidia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_72137_1	177437.HRM2_12930	6.91e-93	280.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2WU0J@28221|Deltaproteobacteria,2MMVY@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_99532_1	1049564.TevJSym_ad01420	4.29e-104	312.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1J5JA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_31647_1	765913.ThidrDRAFT_1063	2.28e-37	145.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales	135613|Chromatiales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_119867_1	2340.JV46_11610	1.71e-60	190.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1JBM2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
k59_160427_1	225937.HP15_2744	6.8e-80	243.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,467CR@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	NnrU protein	nnrU	-	-	-	-	-	-	-	-	-	-	-	NnrU
k59_194285_1	1233488.S4T7A1_9CAUD	3.65e-23	94.0	4QEW9@10239|Viruses,4QWFV@35237|dsDNA viruses  no RNA stage,4QRGP@28883|Caudovirales,4QNCN@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_51917_1	987059.RBXJA2T_17896	5.74e-14	67.8	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,1KKKW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_51917_2	1165841.SULAR_06938	3.39e-81	240.0	COG1145@1|root,COG1145@2|Bacteria,1QZ2K@1224|Proteobacteria,42SFI@68525|delta/epsilon subdivisions,2YPQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_51917_3	1437610.BREU_0281	6.48e-16	76.3	COG0192@1|root,COG0192@2|Bacteria,2IEP4@201174|Actinobacteria,4CZT4@85004|Bifidobacteriales	201174|Actinobacteria	H	S-adenosylmethionine synthetase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_18125_1	1122613.ATUP01000001_gene1600	2.51e-13	67.0	COG0454@1|root,COG0456@2|Bacteria,1RH0C@1224|Proteobacteria,2U9B4@28211|Alphaproteobacteria,440B5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	phnO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_18125_2	101028.EKJ75357	1.83e-05	49.7	COG3338@1|root,KOG0382@2759|Eukaryota,39UTB@33154|Opisthokonta,3NYY5@4751|Fungi,3QQ4Q@4890|Ascomycota,211T9@147550|Sordariomycetes,3TJQH@5125|Hypocreales,1FM77@110618|Nectriaceae	4751|Fungi	P	Eukaryotic-type carbonic anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	Carb_anhydrase
k59_180488_1	1443665.JACA01000001_gene2859	2.08e-107	325.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1HXFR@117743|Flavobacteriia,2YI98@290174|Aquimarina	976|Bacteroidetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_72140_1	983545.Glaag_2327	3.47e-70	244.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_166957_1	1255043.TVNIR_1306	6.59e-22	99.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_58757_1	1121875.KB907547_gene2872	2.72e-102	300.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1HXZT@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_194291_1	28229.ND2E_1970	2.42e-51	176.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,2Q78K@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_78946_1	929562.Emtol_3681	3.92e-48	170.0	COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,47NQE@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294,ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
k59_106361_1	2340.JV46_27780	6.64e-16	75.5	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
k59_106361_2	2340.JV46_09960	1.91e-23	101.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_165766_1	4096.XP_009794768.1	0.000201	47.8	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta	35493|Streptophyta	E	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3,rve
k59_36856_1	268746.Q58MM0_BPPRM	1.24e-34	134.0	4QHPV@10239|Viruses,4QWVT@35237|dsDNA viruses  no RNA stage,4QTVP@28883|Caudovirales,4QICC@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36856_2	1141136.K4F9L0_9CAUD	7.6e-05	50.4	4QAJ5@10239|Viruses,4QUS9@35237|dsDNA viruses  no RNA stage,4QPY5@28883|Caudovirales,4QHUT@10662|Myoviridae	10662|Myoviridae	S	Major capsid protein Gp23	-	GO:0005575,GO:0019012,GO:0019028,GO:0044423	-	-	-	-	-	-	-	-	-	-	-
k59_43656_1	387093.SUN_2219	1.73e-146	425.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_16772_1	2340.JV46_13820	6.33e-52	171.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1JA45@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_3411_1	1129794.C427_1896	3.73e-83	255.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,464XH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0714 MoxR-like ATPases	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_98335_1	247634.GPB2148_430	1.5e-101	302.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1J4Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_84761_1	292414.TM1040_2000	2.66e-40	150.0	COG1574@1|root,COG1574@2|Bacteria,1R53N@1224|Proteobacteria,2VF84@28211|Alphaproteobacteria,4NBCU@97050|Ruegeria	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_213390_2	1165841.SULAR_01698	5.28e-171	485.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_64206_1	1158146.KB907123_gene598	1.87e-54	179.0	COG1028@1|root,COG1028@2|Bacteria,1RFQT@1224|Proteobacteria,1S58Z@1236|Gammaproteobacteria,1X0HD@135613|Chromatiales	135613|Chromatiales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_36874_1	1123399.AQVE01000003_gene2067	2.06e-56	187.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,46027@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_179139_1	1223523.H340_17487	1.59e-36	132.0	COG1834@1|root,COG1834@2|Bacteria,2H33J@201174|Actinobacteria	201174|Actinobacteria	E	N-dimethylarginine dimethylaminohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
k59_179139_2	435591.BDI_0215	3.05e-16	80.1	COG0534@1|root,COG0534@2|Bacteria,4NFIR@976|Bacteroidetes,2FMSA@200643|Bacteroidia,22X5G@171551|Porphyromonadaceae	976|Bacteroidetes	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_43672_1	933262.AXAM01000003_gene2808	5.84e-28	115.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2MIAK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578,ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_98346_1	1266914.ATUK01000015_gene975	8.13e-49	168.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_98346_2	2340.JV46_15830	1.25e-08	55.1	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1J4FG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
k59_23534_1	472759.Nhal_3424	2.77e-23	92.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SF76@1236|Gammaproteobacteria,1WZJF@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_23534_2	1485545.JQLW01000006_gene457	1.32e-21	93.2	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria	1224|Proteobacteria	O	Peptidase M48	agmM	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_84772_1	1121403.AUCV01000074_gene1301	8.41e-41	154.0	COG0642@1|root,COG4251@1|root,COG0642@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CDW@68525|delta/epsilon subdivisions,2X8IN@28221|Deltaproteobacteria,2MPPH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_16795_1	3659.XP_004154167.1	6.89e-154	436.0	COG0843@1|root,2S5UM@2759|Eukaryota	2759|Eukaryota	C	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
k59_36877_1	1165841.SULAR_02748	2.09e-109	330.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_145668_2	1230476.C207_02437	2.4e-22	95.1	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria,3JSU2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha beta hydrolase	MA20_16715	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Lipase_2
k59_118766_1	697282.Mettu_1336	6.14e-108	330.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XDNZ@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_159149_1	1168034.FH5T_21805	2.93e-33	125.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_145674_1	1179773.BN6_28570	6.98e-22	101.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4DZJG@85010|Pseudonocardiales	201174|Actinobacteria	T	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_23541_1	879212.DespoDRAFT_02386	1.8e-68	221.0	COG2357@1|root,COG2357@2|Bacteria,1RCHE@1224|Proteobacteria,42PPK@68525|delta/epsilon subdivisions,2WJBS@28221|Deltaproteobacteria,2MHSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_50736_2	1165841.SULAR_08327	1.01e-84	255.0	COG0388@1|root,COG0388@2|Bacteria,1PZZZ@1224|Proteobacteria,42REP@68525|delta/epsilon subdivisions,2YP77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_98369_1	1165841.SULAR_07218	4.19e-149	425.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2YMJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0625	GcpE
k59_57412_1	1280001.BAOA01000031_gene5175	1.18e-48	176.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Calx-beta,He_PIG,OmpA_membrane,VWA_2,fn3
k59_159161_1	1408473.JHXO01000006_gene1315	5.9e-68	212.0	COG0500@1|root,COG2226@2|Bacteria,4PHN8@976|Bacteroidetes,2FVJG@200643|Bacteroidia	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70982_1	102129.Lepto7375DRAFT_7505	4.9e-40	152.0	COG2351@1|root,COG2351@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
k59_30549_1	1165841.SULAR_09769	1.12e-116	338.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2YM7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0510	DapB_C,DapB_N
k59_98389_2	502025.Hoch_6444	8.39e-144	427.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_172770_2	585423.KR49_03635	2.3e-22	98.6	COG2931@1|root,COG2931@2|Bacteria,1G3V2@1117|Cyanobacteria,1GZKW@1129|Synechococcus	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PAP2
k59_91474_1	1397666.RS24_00690	5.14e-29	115.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,4BQ95@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_165842_1	1047013.AQSP01000123_gene1533	1.96e-23	107.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_206706_1	1173029.JH980292_gene3090	2.97e-53	197.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
k59_172772_1	1165841.SULAR_09764	5.07e-104	312.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_111677_1	1267534.KB906759_gene1773	4.38e-05	48.1	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria,2JNBY@204432|Acidobacteriia	204432|Acidobacteriia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_70996_1	1165841.SULAR_06038	1.83e-123	369.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_206714_1	768671.ThimaDRAFT_3237	6.79e-24	97.4	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,1SCHA@1236|Gammaproteobacteria,1WZU8@135613|Chromatiales	135613|Chromatiales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_105039_2	1131269.AQVV01000030_gene275	2.77e-35	131.0	29MQ2@1|root,308MT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_186268_1	1163617.SCD_n00829	3.42e-06	48.9	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,2WEVJ@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_186268_2	1123401.JHYQ01000001_gene1887	1.04e-30	114.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,4628I@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k59_138776_1	580332.Slit_2552	1.57e-96	298.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k59_30570_1	2340.JV46_28910	4.29e-56	176.0	COG0607@1|root,COG0607@2|Bacteria,1QMXA@1224|Proteobacteria,1S6DI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Pfam Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_165863_1	1288494.EBAPG3_19770	9.47e-27	113.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria,372RG@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_50777_1	1165841.SULAR_06018	1.47e-124	370.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_36916_1	396588.Tgr7_2026	1.76e-40	157.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1WW7V@135613|Chromatiales	135613|Chromatiales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_152447_1	314254.OA2633_01544	2.42e-30	126.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,2U2SA@28211|Alphaproteobacteria,43ZG5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_165867_2	595460.RRSWK_02905	7.63e-44	152.0	COG0299@1|root,COG0299@2|Bacteria,2IZ96@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_200004_1	1123253.AUBD01000009_gene2225	7.78e-76	243.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1X3CQ@135614|Xanthomonadales	135614|Xanthomonadales	E	Transporter	yhiP	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_30573_1	1165841.SULAR_09939	2.1e-46	152.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2YNX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_57458_1	1265505.ATUG01000002_gene2199	7.04e-10	60.5	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,42QHA@68525|delta/epsilon subdivisions,2WMFT@28221|Deltaproteobacteria,2MHYN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_159192_1	1174528.JH992890_gene608	9.63e-44	164.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_111947_1	1348114.OM33_15870	1.15e-30	120.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,2Q0BR@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_111947_2	1041159.AZUW01000017_gene2190	2.04e-13	69.7	2E3VP@1|root,32YSV@2|Bacteria,1RFZF@1224|Proteobacteria,2UFT8@28211|Alphaproteobacteria,4BK77@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166213_1	550540.Fbal_0091	4.47e-65	211.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_166213_2	413404.Rmag_0714	1.9e-11	65.9	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1J70K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_139138_1	323261.Noc_2156	1.4e-56	186.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1WWDH@135613|Chromatiales	135613|Chromatiales	D	Belongs to the ParA family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
k59_139138_2	349124.Hhal_0477	1.54e-19	85.1	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1WXKN@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_147052_1	56780.SYN_02705	6.05e-111	325.0	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,42QAW@68525|delta/epsilon subdivisions,2WIXS@28221|Deltaproteobacteria,2MRNN@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	ATPase MipZ	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_147052_2	511062.GU3_10050	2.57e-08	52.0	COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria,1Y4N2@135624|Aeromonadales	135624|Aeromonadales	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
k59_4802_1	1168034.FH5T_05000	8.25e-63	199.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,2FMST@200643|Bacteroidia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_4802_2	1168034.FH5T_04995	3.26e-13	63.9	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 9.82	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
k59_147054_1	391587.KAOT1_20017	1.63e-125	366.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HXDJ@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
k59_99616_1	387093.SUN_0591	8.72e-55	184.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2YMRT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_51995_1	1163409.UUA_11758	4.87e-31	121.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1X35Q@135614|Xanthomonadales	135614|Xanthomonadales	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_11152_1	595460.RRSWK_03715	5.28e-82	250.0	COG0714@1|root,COG0714@2|Bacteria,2IX1F@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_119992_1	883069.HMPREF9238_01293	4.64e-28	116.0	COG0591@1|root,COG0591@2|Bacteria,2HF7Z@201174|Actinobacteria,4D3DX@85005|Actinomycetales	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_106494_1	1123368.AUIS01000003_gene1800	4.71e-10	62.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_31741_1	2340.JV46_14800	8.35e-111	327.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1J57J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695	FA_synthesis
k59_18221_1	857087.Metme_2940	5.53e-33	124.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1XDJ2@135618|Methylococcales	135618|Methylococcales	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_79045_1	378806.STAUR_5206	4.81e-89	280.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,42NBE@68525|delta/epsilon subdivisions,2WMG2@28221|Deltaproteobacteria,2YUJX@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
k59_72264_1	631362.Thi970DRAFT_03598	1.88e-111	338.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales	135613|Chromatiales	CI	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_208008_1	118168.MC7420_4451	8.4e-46	168.0	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG3850@1|root,COG4191@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHXQ@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_160560_2	483219.LILAB_20150	3.36e-61	203.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,439F3@68525|delta/epsilon subdivisions,2X4QF@28221|Deltaproteobacteria,2YZE7@29|Myxococcales	28221|Deltaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_153711_1	1123514.KB905903_gene347	2.01e-41	148.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,45ZP6@72273|Thiotrichales	72273|Thiotrichales	L	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_52007_1	706587.Desti_0887	1.83e-67	207.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_52007_2	706587.Desti_0895	1.57e-36	127.0	COG5423@1|root,COG5423@2|Bacteria	2|Bacteria	M	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
k59_79051_1	234267.Acid_7231	2.19e-40	150.0	COG3533@1|root,COG3533@2|Bacteria,3Y6B7@57723|Acidobacteria	57723|Acidobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
k59_24843_1	1195246.AGRI_09981	2.51e-68	226.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,464Q7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
k59_187443_1	272134.KB731324_gene5678	0.000266	48.5	COG1100@1|root,COG1672@1|root,COG1100@2|Bacteria,COG1672@2|Bacteria,1G5IV@1117|Cyanobacteria,1HATH@1150|Oscillatoriales	1117|Cyanobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,CHAT,TIR_2,Trypsin_2
k59_106507_2	46234.ANA_C11881	1.35e-113	333.0	COG5464@1|root,COG5464@2|Bacteria,1G211@1117|Cyanobacteria,1HS60@1161|Nostocales	1117|Cyanobacteria	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,PDDEXK_2
k59_72276_2	1049564.TevJSym_au00280	8.64e-43	141.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1J6K6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_4831_1	349521.HCH_03259	5.76e-76	238.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,1RY10@1236|Gammaproteobacteria,1XNMD@135619|Oceanospirillales	1236|Gammaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_33
k59_208014_2	1268239.PALB_19440	1.94e-20	90.5	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,1S5DM@1236|Gammaproteobacteria,2Q2DQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_133592_1	742767.HMPREF9456_01314	1.73e-09	63.5	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FQ8Z@200643|Bacteroidia,22X3T@171551|Porphyromonadaceae	976|Bacteroidetes	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_173888_1	686340.Metal_2130	9.15e-84	259.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1T9DW@1236|Gammaproteobacteria,1XG6V@135618|Methylococcales	135618|Methylococcales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k59_24846_1	1249627.D779_4054	2.78e-175	503.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alkaline phosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_147081_1	1129374.AJE_01059	7.13e-45	160.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,46442@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_119994_1	4081.Solyc01g007320.2.1	0.0	910.0	COG0055@1|root,COG0355@1|root,KOG1350@2759|Eukaryota,KOG1758@2759|Eukaryota,37K5M@33090|Viridiplantae,3GCIP@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit beta	atpB	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_DE_N,ATP-synt_ab,ATP-synt_ab_N
k59_119994_2	3702.ATCG00470.1	1.37e-77	232.0	COG0355@1|root,KOG1758@2759|Eukaryota,37UFP@33090|Viridiplantae,3GIN2@35493|Streptophyta	35493|Streptophyta	C	ATP synthase epsilon chain	atpE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009526,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009941,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_99639_1	313596.RB2501_08885	2.76e-89	272.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_201067_1	338963.Pcar_0911	1.76e-40	150.0	COG2199@1|root,COG2984@1|root,COG2984@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF,GGDEF,PAS_2,PHY
k59_4839_1	1279009.ADICEAN_04034	2.62e-21	97.8	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
k59_38045_1	1121904.ARBP01000016_gene5281	2.59e-91	276.0	COG2084@1|root,COG2084@2|Bacteria,4NEF7@976|Bacteroidetes,47N6M@768503|Cytophagia	976|Bacteroidetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_173896_1	2340.JV46_23640	2.83e-142	443.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_52022_1	234267.Acid_4384	1.21e-46	160.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
k59_140026_1	340177.Cag_0763	3.2e-16	83.2	COG1330@1|root,COG1330@2|Bacteria,1FEMY@1090|Chlorobi	1090|Chlorobi	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k59_92811_2	933262.AXAM01000016_gene189	1.9e-39	137.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MIHA@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
k59_65586_1	553385.JEMF01000021_gene3160	7.68e-61	202.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XHK9@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_52023_1	1121015.N789_12940	3.12e-27	112.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_86095_1	1195246.AGRI_07190	2.16e-82	254.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_72293_1	1120966.AUBU01000016_gene3070	1.89e-38	148.0	COG1361@1|root,COG2911@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,4PPBJ@976|Bacteroidetes,47TYA@768503|Cytophagia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_106525_1	518766.Rmar_0857	2.47e-27	105.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1FJB0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_106525_2	1122216.AUHW01000005_gene478	3.1e-19	82.4	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4H4PJ@909932|Negativicutes	909932|Negativicutes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_147101_1	1415780.JPOG01000001_gene2926	6.52e-127	371.0	COG0702@1|root,COG0702@2|Bacteria,1QR5G@1224|Proteobacteria,1SMSE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
k59_133601_2	1249627.D779_2374	2.07e-54	184.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1WWIC@135613|Chromatiales	135613|Chromatiales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_45099_1	313603.FB2170_08709	8.53e-62	209.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWY2@117743|Flavobacteriia,2PGWY@252356|Maribacter	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_106529_1	1123261.AXDW01000001_gene1418	1.45e-21	94.4	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1X6EE@135614|Xanthomonadales	135614|Xanthomonadales	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_79080_1	1168034.FH5T_07760	1.89e-106	321.0	COG0793@1|root,COG4206@1|root,COG0793@2|Bacteria,COG4206@2|Bacteria,4NEF4@976|Bacteroidetes,2FVM1@200643|Bacteroidia	976|Bacteroidetes	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
k59_133607_1	266835.14023707	2.06e-08	53.5	COG3609@1|root,COG3609@2|Bacteria,1P0RI@1224|Proteobacteria,2UU82@28211|Alphaproteobacteria,43MBS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	addiction module antidote protein	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
k59_24867_1	1280953.HOC_18124	8.35e-150	441.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,43Z43@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	pyruvate flavodoxin ferredoxin oxidoreductase	MA20_01045	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_58888_2	4565.Traes_2AL_6FA19E019.1	7.25e-83	245.0	COG0048@1|root,KOG1750@2759|Eukaryota,37UKS@33090|Viridiplantae,3GIMC@35493|Streptophyta,3KZQG@4447|Liliopsida,3IH6R@38820|Poales	35493|Streptophyta	J	Rps12 protein	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_181172_1	598659.NAMH_0970	6.56e-115	347.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_208462_1	1165841.SULAR_06858	7.8e-122	355.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,TPR_8,VWA_2
k59_38416_1	765913.ThidrDRAFT_3389	2.86e-89	280.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1WW58@135613|Chromatiales	135613|Chromatiales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_201600_1	502025.Hoch_5002	3.92e-71	236.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_214860_1	237368.SCABRO_01395	4.06e-66	217.0	COG4262@1|root,COG4262@2|Bacteria,2J4XV@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_63892_1	2340.JV46_05320	3.36e-80	254.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,1S0H0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_63892_2	2340.JV46_05330	1.11e-54	174.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,1S6Y2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
k59_165383_1	1123368.AUIS01000004_gene239	1.71e-75	233.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,2NBWI@225057|Acidithiobacillales	225057|Acidithiobacillales	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_124896_1	78898.MVEG_02603T0	7.27e-82	260.0	COG0129@1|root,KOG2448@2759|Eukaryota,38F28@33154|Opisthokonta,3NUBR@4751|Fungi,1GS3V@112252|Fungi incertae sedis	4751|Fungi	E	Dehydratase family	ILV3	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006549,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_185794_1	2340.JV46_27400	1.84e-05	43.9	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S6HX@1236|Gammaproteobacteria,1JBUQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pnaB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
k59_185794_2	2340.JV46_27390	7.07e-187	528.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1J4FV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_16403_1	717772.THIAE_05235	8.8e-07	48.5	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,460U2@72273|Thiotrichales	72273|Thiotrichales	S	CYTH	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
k59_16403_2	2340.JV46_03890	1.79e-40	149.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1JBY1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_131642_2	765911.Thivi_3658	1.76e-24	95.1	2EE2B@1|root,32X3W@2|Bacteria,1N4QZ@1224|Proteobacteria,1SB3P@1236|Gammaproteobacteria,1WZ1S@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118314_1	2340.JV46_20400	1.6e-66	216.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1J5MF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase subunit	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_118314_2	870187.Thini_1439	8.55e-22	96.7	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_16407_1	1122604.JONR01000007_gene2798	1.54e-102	322.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1X3DK@135614|Xanthomonadales	135614|Xanthomonadales	J	due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_36542_1	83219.PM02_14455	2.57e-15	75.1	COG1802@1|root,COG1802@2|Bacteria,1P945@1224|Proteobacteria,2TV2V@28211|Alphaproteobacteria,3ZXCC@60136|Sulfitobacter	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_43403_2	686340.Metal_3804	3.88e-19	87.8	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1XE58@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_36543_2	1297742.A176_00787	7.65e-06	50.1	COG1398@1|root,COG1398@2|Bacteria,1QA95@1224|Proteobacteria,439A9@68525|delta/epsilon subdivisions,2X4HT@28221|Deltaproteobacteria,2YZ1J@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_118331_1	1122975.AQVC01000031_gene670	9.92e-20	95.1	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,2FPVW@200643|Bacteroidia,22XA7@171551|Porphyromonadaceae	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
k59_206308_1	1437824.BN940_08286	2.58e-18	84.3	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	sqr	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_3056_2	2340.JV46_12220	3.66e-90	279.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1J4D3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2699	PALP,Thr_dehydrat_C
k59_178872_1	1165841.SULAR_05503	1.94e-85	259.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_16422_1	699218.HMPREF0889_1638	3.14e-59	187.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4H3ZR@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k59_3059_1	313596.RB2501_10070	6.99e-92	287.0	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3059_2	313596.RB2501_10065	5.1e-35	122.0	COG1595@1|root,COG1595@2|Bacteria,4NMCX@976|Bacteroidetes,1I1EN@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_131660_1	454957.IA64_00755	1.55e-13	72.4	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,1X2Y2@135614|Xanthomonadales	135614|Xanthomonadales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
k59_138281_1	387093.SUN_0476	1.61e-21	89.0	COG4951@1|root,COG4951@2|Bacteria,1PC94@1224|Proteobacteria,42NUB@68525|delta/epsilon subdivisions,2YMWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Domain of unknown function (DUF1882)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1882
k59_138281_2	1165841.SULAR_09059	1.04e-113	336.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_50489_1	387093.SUN_1807	6.98e-69	215.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_50489_2	387093.SUN_1812	1.6e-115	339.0	COG3869@1|root,COG3869@2|Bacteria,1R4ST@1224|Proteobacteria,42MP2@68525|delta/epsilon subdivisions,2YNUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP:guanido phosphotransferase, N-terminal domain	-	-	2.7.3.2,2.7.3.3	ko:K00933,ko:K00934	ko00330,ko01100,map00330,map01100	M00047	R00554,R01881	RC00002,RC00203	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ATP-gua_Ptrans,ATP-gua_PtransN
k59_84377_1	1356852.N008_11775	1.77e-12	69.3	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_30192_1	1165841.SULAR_05923	3.29e-137	403.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2YMQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_57044_1	396588.Tgr7_0944	4.49e-132	385.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1WXTC@135613|Chromatiales	135613|Chromatiales	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_43413_1	1165841.SULAR_05448	2.73e-97	302.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_70624_1	1004149.AFOE01000038_gene892	1.58e-90	275.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_131670_1	927658.AJUM01000040_gene832	1.25e-12	67.4	2DX5A@1|root,343EM@2|Bacteria,4P5EZ@976|Bacteroidetes,2FYQS@200643|Bacteroidia,3XKVJ@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9740_1	232346.JHQL01000002_gene1013	5.15e-96	291.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1XH60@135619|Oceanospirillales	135619|Oceanospirillales	Q	Fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
k59_138295_1	1165841.SULAR_04257	1.18e-104	315.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_84395_1	2340.JV46_04130	1.18e-99	300.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1J4KY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	iPC815.YPO2896,iYL1228.KPN_02862	Aminotran_5
k59_84396_1	1165841.SULAR_02663	4.15e-113	339.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_63931_1	589865.DaAHT2_0933	5.45e-32	124.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2MJ1I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_77497_1	228410.NE0619	1.22e-22	96.3	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,372KR@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_3092_1	879212.DespoDRAFT_01456	1.48e-46	152.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria,2MM3T@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
k59_63936_1	1165841.SULAR_10479	7.76e-116	352.0	COG1287@1|root,COG1287@2|Bacteria,1R8YG@1224|Proteobacteria,43BIB@68525|delta/epsilon subdivisions,2YT8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharide transferase	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_138300_3	485915.Dret_2298	9.15e-83	260.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Q0C@68525|delta/epsilon subdivisions,2WIIZ@28221|Deltaproteobacteria,2MDPJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
k59_9755_1	1165841.SULAR_09959	1.39e-148	422.0	COG4121@1|root,COG4121@2|Bacteria,1Q8T8@1224|Proteobacteria,42RAP@68525|delta/epsilon subdivisions,2YP3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_9755_2	697282.Mettu_4118	2.7e-08	54.7	COG3837@1|root,COG3837@2|Bacteria,1R0Y0@1224|Proteobacteria,1T54B@1236|Gammaproteobacteria,1XH1S@135618|Methylococcales	135618|Methylococcales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_36574_1	765913.ThidrDRAFT_0096	6.22e-42	155.0	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,1RNZA@1236|Gammaproteobacteria,1WXHK@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70637_1	338969.Rfer_0505	1.28e-39	147.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VZWB@28216|Betaproteobacteria,4AJ8B@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k59_57057_1	1123057.P872_21910	1.87e-85	268.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,47KCH@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
k59_172373_1	886293.Sinac_4445	5.72e-29	114.0	COG0745@1|root,COG0745@2|Bacteria,2IX2M@203682|Planctomycetes	203682|Planctomycetes	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07657,ko:K07662	ko01503,ko02020,map01503,map02020	M00434,M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_3098_1	886293.Sinac_6188	1.89e-48	173.0	COG0129@1|root,COG0129@2|Bacteria,2IWXV@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_71010_1	1198232.CYCME_1119	9.36e-70	224.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,461RJ@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_165872_1	1165841.SULAR_08627	4.54e-44	147.0	2AKA4@1|root,31B0R@2|Bacteria,1Q6NQ@1224|Proteobacteria,433FV@68525|delta/epsilon subdivisions,2YSK0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152455_1	387093.SUN_0595	1.8e-29	109.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2YPX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_152455_2	387093.SUN_0596	8.06e-35	129.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2YMAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_213448_1	4081.Solyc01g007640.2.1	1.6e-92	301.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_10101_1	768671.ThimaDRAFT_3002	7.11e-80	265.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1WW6H@135613|Chromatiales	135613|Chromatiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_105059_1	929703.KE386491_gene985	4.55e-27	115.0	COG2972@1|root,COG2972@2|Bacteria,4NHXJ@976|Bacteroidetes,47K62@768503|Cytophagia	976|Bacteroidetes	T	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Pentapeptide
k59_118840_1	1235803.C825_00967	2.8e-21	99.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,2FNT9@200643|Bacteroidia,22WDA@171551|Porphyromonadaceae	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_77783_1	2340.JV46_08110	1.04e-77	257.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1J4RE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_4025	PEPcase
k59_193139_1	1123399.AQVE01000042_gene1326	2.58e-33	119.0	COG0454@1|root,COG0454@2|Bacteria,1QUS5@1224|Proteobacteria,1RRHY@1236|Gammaproteobacteria,4630T@72273|Thiotrichales	72273|Thiotrichales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_165882_1	2340.JV46_18780	1.81e-35	124.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	gloA	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_105063_1	1165841.SULAR_07590	1.67e-70	227.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_43729_1	313596.RB2501_07485	3.19e-103	327.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_172805_1	4155.Migut.G00885.1.p	1.88e-122	350.0	KOG1721@1|root,KOG1721@2759|Eukaryota,38A9Z@33090|Viridiplantae,3GY91@35493|Streptophyta,44UXV@71274|asterids	35493|Streptophyta	S	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10108_1	1049564.TevJSym_ac00030	9.46e-76	233.0	COG2863@1|root,COG2863@2|Bacteria,1RBXV@1224|Proteobacteria,1SEAS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_23583_1	314278.NB231_17298	5.14e-06	47.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1WWEP@135613|Chromatiales	135613|Chromatiales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_23583_2	876044.IMCC3088_2588	3.94e-20	90.5	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_6336_1	395493.BegalDRAFT_2924	1.17e-81	260.0	COG2198@1|root,COG2198@2|Bacteria,1QY43@1224|Proteobacteria,1S0ZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	fimL	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_33269_1	1168034.FH5T_11930	1.89e-81	253.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,2FMJV@200643|Bacteroidia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_188715_1	1165841.SULAR_05818	4.8e-61	199.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2YMZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_188715_2	1165841.SULAR_05813	1.98e-44	156.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_67293_1	1192759.AKIB01000028_gene2028	1.12e-37	147.0	COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3386@1|root,COG3391@1|root,COG5276@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2UHRC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FGMQ	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,He_PIG,Laminin_G_3
k59_46827_1	713586.KB900536_gene2634	5.56e-67	212.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_87407_2	497964.CfE428DRAFT_4947	8.55e-33	120.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
k59_87407_3	1396418.BATQ01000087_gene1046	2.95e-52	177.0	COG0438@1|root,COG0438@2|Bacteria,46UG2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_141503_1	1165841.SULAR_08020	1.16e-55	174.0	COG0089@1|root,COG0089@2|Bacteria,1QJHM@1224|Proteobacteria,42TRQ@68525|delta/epsilon subdivisions,2YPUJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_141503_2	1165841.SULAR_08015	6.77e-33	120.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2YN0T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_46832_1	395493.BegalDRAFT_0268	2.68e-15	80.5	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,DUF4347,Lactonase,Laminin_G_3
k59_60453_1	1036674.A28LD_1557	3.23e-06	52.4	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,2QFS1@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_134955_2	1168034.FH5T_18220	1.34e-54	171.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,2FT22@200643|Bacteroidia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_134955_3	1168034.FH5T_18225	6.16e-28	103.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_175606_1	1121875.KB907549_gene1749	2.27e-43	147.0	COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,1IINH@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_67306_1	1165841.SULAR_03098	1.19e-96	298.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_6352_1	1168065.DOK_01059	9.37e-78	243.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1J5GB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Phage integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_6352_2	926561.KB900618_gene449	6.32e-27	108.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_215989_2	1168034.FH5T_00025	2.95e-53	174.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,2FN60@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_87418_1	1049564.TevJSym_ag00660	4.24e-130	400.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM von Willebrand factor type A	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	-
k59_67307_1	1165841.SULAR_00560	3.06e-87	266.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMVY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_94360_1	1382306.JNIM01000001_gene1446	6.76e-61	214.0	COG1020@1|root,COG1020@2|Bacteria,2G86H@200795|Chloroflexi	2|Bacteria	Q	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_80612_1	264198.Reut_C6415	1.25e-126	372.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,2WESJ@28216|Betaproteobacteria,1KHUQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	zinc-finger of transposase IS204/IS1001/IS1096/IS1165	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_195888_1	1165841.SULAR_07300	3.35e-124	373.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_195888_2	387093.SUN_2151	5.25e-19	81.3	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2YN9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_141522_1	1232437.KL662020_gene705	2.47e-51	177.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_134960_1	1392498.JQLH01000001_gene274	3.87e-76	239.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia,2PGA1@252356|Maribacter	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_188727_1	237609.PSAKL28_07670	7.02e-47	163.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k59_46855_1	1168034.FH5T_06120	6.79e-70	231.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_94367_1	1165841.SULAR_09494	3.46e-186	529.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,42U1I@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	IV02_00930	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k59_141527_1	1168034.FH5T_14150	5.79e-102	298.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,2FM4M@200643|Bacteroidia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_168916_1	765912.Thimo_0707	3.42e-101	313.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_148653_1	1165096.ARWF01000001_gene1739	2.63e-43	144.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KMRE@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
k59_148653_2	626887.J057_04906	2.19e-36	133.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,4652P@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Ammonium transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_182201_1	1589733.A0A0C5AAX2_9CAUD	3.75e-19	100.0	4QEE7@10239|Viruses,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94371_1	765912.Thimo_2568	2.03e-27	101.0	2E3CN@1|root,32YBX@2|Bacteria,1N716@1224|Proteobacteria,1SEFN@1236|Gammaproteobacteria,1WYWS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_216010_1	1304880.JAGB01000001_gene819	5.6e-48	169.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_67321_1	1523503.JPMY01000002_gene3958	6.29e-97	296.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k59_94373_1	247639.MGP2080_12297	2.53e-33	129.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	mechanosensitive ion channel	ynaI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_108121_1	1385517.N800_15265	8.93e-45	145.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,1X7FM@135614|Xanthomonadales	135614|Xanthomonadales	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_195903_1	1198232.CYCME_0106	2.95e-43	152.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,45ZU4@72273|Thiotrichales	72273|Thiotrichales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_195903_2	857087.Metme_1801	1.48e-39	140.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1XEKP@135618|Methylococcales	135618|Methylococcales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_188731_1	2340.JV46_19910	4.11e-120	349.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,1J5BS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407	PEP_mutase
k59_162006_1	563040.Saut_1382	5.51e-34	122.0	2AIVI@1|root,30TB8@2|Bacteria,1PD2X@1224|Proteobacteria,42TB3@68525|delta/epsilon subdivisions,2YPG6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162006_2	1165841.SULAR_01788	6.23e-66	216.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_134970_1	1227266.HMPREF1551_00356	7.85e-153	436.0	COG3039@1|root,COG3039@2|Bacteria,4NGY9@976|Bacteroidetes,1I0T1@117743|Flavobacteriia,1ESPR@1016|Capnocytophaga	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
k59_141540_1	1411123.JQNH01000001_gene1212	1.34e-44	151.0	COG0431@1|root,COG0431@2|Bacteria,1RDFK@1224|Proteobacteria,2U70M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_33314_1	1122201.AUAZ01000014_gene214	2.31e-49	166.0	COG0546@1|root,COG0546@2|Bacteria,1RHAA@1224|Proteobacteria,1S67H@1236|Gammaproteobacteria,46DH9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
k59_189104_1	768671.ThimaDRAFT_2563	3.18e-33	119.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1WY2E@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM DJ-1 family protein	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_189104_2	379731.PST_4082	4.07e-11	66.6	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1Z0GY@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_101350_1	768671.ThimaDRAFT_2144	1.36e-101	323.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_135363_1	1165841.SULAR_07153	1.16e-157	474.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2YSXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
k59_81082_1	1173029.JH980292_gene1177	9.52e-36	142.0	COG0642@1|root,COG0745@1|root,COG2905@1|root,COG4251@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2905@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_162323_1	1047013.AQSP01000059_gene2095	2.19e-26	107.0	COG1757@1|root,COG1757@2|Bacteria,2NRD3@2323|unclassified Bacteria	2|Bacteria	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k59_162323_2	1089550.ATTH01000001_gene448	1.95e-12	68.9	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_60886_2	1123371.ATXH01000030_gene2005	9.37e-35	128.0	COG1694@1|root,COG3956@2|Bacteria,2GHCS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
k59_114369_1	1168034.FH5T_19360	4.1e-103	313.0	COG5476@1|root,COG5476@2|Bacteria,4NG23@976|Bacteroidetes,2FQI1@200643|Bacteroidia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
k59_94737_1	459495.SPLC1_S051180	5.54e-50	181.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G0BI@1117|Cyanobacteria,1H9XU@1150|Oscillatoriales	1117|Cyanobacteria	S	Soluble NSF attachment protein, SNAP	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
k59_176034_1	1165841.SULAR_05573	1.61e-163	477.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_13330_1	1286106.MPL1_07942	1.29e-14	80.5	COG1361@1|root,COG1361@2|Bacteria,1QV4I@1224|Proteobacteria,1T281@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53929_1	933262.AXAM01000003_gene2805	5.47e-50	167.0	COG0727@1|root,COG0727@2|Bacteria,1RIJV@1224|Proteobacteria,42U8U@68525|delta/epsilon subdivisions,2WPB4@28221|Deltaproteobacteria,2MKIE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k59_81096_1	1144305.PMI02_04519	4.05e-41	150.0	COG3203@1|root,COG3203@2|Bacteria,1Q96Q@1224|Proteobacteria,2U9II@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_20152_2	1168034.FH5T_07270	7.05e-81	252.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,2FPTN@200643|Bacteroidia	976|Bacteroidetes	M	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_87918_1	1235457.C404_19315	7.24e-27	103.0	2DF7Q@1|root,33391@2|Bacteria,1NB8A@1224|Proteobacteria,2VWDS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13339_1	754477.Q7C_1704	1.3e-49	172.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,460BE@72273|Thiotrichales	72273|Thiotrichales	EGP	major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_176042_1	1165841.SULAR_01958	2.45e-36	133.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_176042_2	1165841.SULAR_01948	7.69e-122	354.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_53940_1	1168034.FH5T_05450	8.64e-13	65.1	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,2FSVU@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG14471 non supervised orthologous group	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_53940_2	1168034.FH5T_05445	1.43e-37	134.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,2FQ6G@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149031_1	215803.DB30_4669	8.77e-97	297.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUGB@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.3.4.14,6.3.4.6,6.4.1.2	ko:K01941,ko:K01961	ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R00774,R04385	RC00040,RC00253,RC00367,RC00378	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_73889_1	1536774.H70357_19070	1.82e-24	108.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NAD_binding_4,PP-binding,ketoacyl-synt
k59_28158_1	1260251.SPISAL_03465	3.37e-22	95.1	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1WX6R@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_68769_1	395493.BegalDRAFT_1286	1.46e-81	252.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_204283_1	1004149.AFOE01000014_gene1079	3.75e-33	123.0	298D5@1|root,2ZVIG@2|Bacteria,4NP2F@976|Bacteroidetes,1I24E@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
k59_204283_2	313596.RB2501_10597	3.5e-29	110.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
k59_136504_1	324057.Pjdr2_4486	1.34e-79	249.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_143334_1	1279017.AQYJ01000029_gene3961	4.51e-82	255.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,464UI@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG4974 Site-specific recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
k59_163675_1	566466.NOR53_1454	7.6e-68	215.0	COG0332@1|root,COG0332@2|Bacteria,1P9I2@1224|Proteobacteria,1S3GP@1236|Gammaproteobacteria,1J7XP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_21316_1	362418.IW19_12790	8.12e-46	168.0	COG0331@1|root,COG2070@1|root,COG0331@2|Bacteria,COG2070@2|Bacteria,4NIXD@976|Bacteroidetes,1I0Z3@117743|Flavobacteriia,2NYPX@237|Flavobacterium	976|Bacteroidetes	I	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1
k59_211192_1	1165841.SULAR_03417	2.36e-86	265.0	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_136509_1	1121405.dsmv_0204	2.14e-95	286.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2MID1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM PhoH family protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_156881_1	102125.Xen7305DRAFT_00022690	1.12e-118	345.0	COG1662@1|root,COG3677@1|root,COG1662@2|Bacteria,COG3677@2|Bacteria,1G617@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_102721_1	1120953.AUBH01000008_gene216	9.91e-24	101.0	COG3540@1|root,COG3540@2|Bacteria,1R5RU@1224|Proteobacteria,1RQUJ@1236|Gammaproteobacteria,46A0E@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
k59_34843_1	479431.Namu_2599	8.62e-56	195.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria,4EVSA@85013|Frankiales	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k59_136510_1	211586.SO_3321	9.14e-84	261.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,1SZQR@1236|Gammaproteobacteria,2QEAJ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_7695_1	240016.ABIZ01000001_gene3760	6.5e-20	93.6	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_21325_1	1165841.SULAR_07720	5.73e-122	350.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2YMPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_197667_1	1165841.SULAR_01813	1.99e-102	302.0	COG0715@1|root,COG0715@2|Bacteria,1MVRA@1224|Proteobacteria,42M17@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	NMT1/THI5 like	thi	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
k59_197667_2	1165841.SULAR_01808	2.42e-18	80.5	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42TAK@68525|delta/epsilon subdivisions,2YPP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_102722_2	1206101.AZXC01000005_gene2733	1.64e-20	91.3	COG2368@1|root,COG2368@2|Bacteria,2GKIQ@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
k59_34847_1	102107.XP_008245779.1	3.61e-23	97.8	COG1850@1|root,2QTI9@2759|Eukaryota,37HQX@33090|Viridiplantae,3GDC3@35493|Streptophyta,4JS2T@91835|fabids	35493|Streptophyta	C	Ribulose bisphosphate carboxylase, large chain	rbcL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.1.3.15,4.1.1.39,6.4.1.2	ko:K01601,ko:K01963	ko00061,ko00620,ko00630,ko00640,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00630,map00640,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00165,M00166,M00376,M00532	R00024,R00742,R03140,R04386	RC00040,RC00172,RC00253,RC00367,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_197669_1	1283300.ATXB01000002_gene2758	2.95e-91	299.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria,1XFZD@135618|Methylococcales	135618|Methylococcales	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
k59_21330_1	1158150.KB906242_gene105	2.68e-30	120.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1WWBR@135613|Chromatiales	135613|Chromatiales	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k59_21330_2	2340.JV46_06590	1.23e-16	79.7	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1J8KX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_204305_1	1216007.AOPM01000012_gene75	3.31e-10	63.5	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,2Q08F@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_204305_2	1217712.F971_00723	9.5e-06	52.4	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,3NII0@468|Moraxellaceae	1236|Gammaproteobacteria	T	Signal transducing histidine kinase, homodimeric domain	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_163688_1	497964.CfE428DRAFT_2659	6.34e-27	110.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_163688_2	1396418.BATQ01000012_gene4451	1.78e-13	71.2	COG1300@1|root,COG1300@2|Bacteria,46SIF@74201|Verrucomicrobia,2IUXK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
k59_82396_1	1122619.KB892279_gene1647	2.85e-37	136.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,3T1RX@506|Alcaligenaceae	28216|Betaproteobacteria	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_82397_1	1026882.MAMP_00105	2e-63	211.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	ychM	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	iSbBS512_1146.SbBS512_E1370	STAS,Sulfate_transp
k59_116303_1	583345.Mmol_1025	9.15e-77	239.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_143355_1	10224.XP_006815462.1	7.87e-06	52.0	KOG4731@1|root,KOG4731@2759|Eukaryota,39880@33154|Opisthokonta,3BIZD@33208|Metazoa,3CZ8K@33213|Bilateria	33208|Metazoa	D	Electron transfer DM13	-	GO:0000226,GO:0003674,GO:0003824,GO:0004497,GO:0004500,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005700,GO:0006584,GO:0006725,GO:0006807,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0008150,GO:0008152,GO:0009712,GO:0009987,GO:0016043,GO:0016491,GO:0016705,GO:0016715,GO:0018958,GO:0022402,GO:0022607,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044237,GO:0044424,GO:0044464,GO:0051225,GO:0055114,GO:0070925,GO:0071704,GO:0071840,GO:1901360,GO:1901564,GO:1901615	-	-	-	-	-	-	-	-	-	-	DM13,DOMON
k59_55246_1	1323663.AROI01000004_gene2087	1.69e-98	307.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	UPF0313 protein	ygiQ	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k59_28187_1	3988.XP_002534684.1	4.81e-28	107.0	2E43Y@1|root,2SB2A@2759|Eukaryota,37X2E@33090|Viridiplantae,3GKUQ@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41651_1	1165841.SULAR_03732	2.35e-89	275.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2YNAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
k59_41651_2	1165841.SULAR_03727	4.56e-25	99.4	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42RW5@68525|delta/epsilon subdivisions,2YT3G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_150180_1	1408424.JHYI01000011_gene1387	3.25e-42	158.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus	91061|Bacilli	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_89289_1	377629.TERTU_1670	1.44e-26	102.0	COG0811@1|root,COG0811@2|Bacteria,1MUNJ@1224|Proteobacteria,1RZ2K@1236|Gammaproteobacteria,2PQB3@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_89289_2	377629.TERTU_1671	1.64e-59	190.0	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,2PPX7@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_110001_1	555779.Dthio_PD3191	2.05e-42	145.0	COG3012@1|root,COG3012@2|Bacteria,1QU5B@1224|Proteobacteria,43D30@68525|delta/epsilon subdivisions,2X8A5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
k59_96444_2	292415.Tbd_2456	5.44e-63	202.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,1KRF9@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_170947_2	998674.ATTE01000001_gene2551	4.96e-64	202.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,1S3U0@1236|Gammaproteobacteria,463WR@72273|Thiotrichales	72273|Thiotrichales	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
k59_82985_1	583355.Caka_1352	7.71e-166	483.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_211696_1	2340.JV46_23670	7.33e-156	452.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1J4GC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_3895,iJN746.PP_5056	Metalloenzyme,Phosphodiest,iPGM_N
k59_69269_1	1122599.AUGR01000006_gene3877	2.51e-26	111.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XIBY@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_69272_1	387093.SUN_1012	2.6e-90	276.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_103180_1	306281.AJLK01000210_gene4125	3.6e-07	49.3	2EG09@1|root,339SB@2|Bacteria,1GGEA@1117|Cyanobacteria,1JMPR@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136978_1	243233.MCA0390	5.21e-66	212.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XEFA@135618|Methylococcales	135618|Methylococcales	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_89741_1	1165841.SULAR_04517	2.33e-42	145.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,42S9D@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_211702_1	1165841.SULAR_04572	3.13e-102	299.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2YQ46@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_143679_1	1416760.AYMS01000004_gene3118	9.44e-14	67.8	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,1IKAU@117743|Flavobacteriia,47J2J@76831|Myroides	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
k59_28772_2	1121405.dsmv_0718	1.31e-11	67.4	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,42XKF@68525|delta/epsilon subdivisions,2WT6J@28221|Deltaproteobacteria,2MNG7@213118|Desulfobacterales	28221|Deltaproteobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_123418_1	2340.JV46_23890	1.92e-87	263.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1J4XA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1137 ABC-type (unclassified) transport system, ATPase component	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_48993_1	796940.HMPREF9628_00291	9.39e-37	141.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_62586_1	340177.Cag_1343	1.75e-56	181.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_62586_2	324925.Ppha_0965	5.65e-14	66.6	2EKDQ@1|root,33E40@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15070_1	745014.OMB55_00024200	1.85e-30	121.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1J4NI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	glnL	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_8189_1	398767.Glov_2499	5.35e-34	129.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,43SK7@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_62591_1	1122179.KB890497_gene2793	5.23e-17	86.7	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4NUCQ@976|Bacteroidetes	976|Bacteroidetes	C	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_130206_1	314278.NB231_08335	3.06e-52	177.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria,1WZIC@135613|Chromatiales	135613|Chromatiales	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_89754_1	688270.Celal_2585	1.35e-62	194.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia,1F948@104264|Cellulophaga	976|Bacteroidetes	J	PFAM Translation initiation factor IF-3, C-terminal domain	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_164144_1	373994.Riv7116_3197	2.31e-50	182.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k59_184455_1	999541.bgla_1g38130	6.79e-57	192.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,1K1TI@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_55767_1	316056.RPC_4507	1.89e-85	253.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2UDW5@28211|Alphaproteobacteria,3K4D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_139402_1	1165841.SULAR_00350	2.73e-151	432.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2YMEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_44302_1	1245471.PCA10_24090	1.34e-20	95.1	COG3203@1|root,COG3203@2|Bacteria,1RBTH@1224|Proteobacteria,1S3AI@1236|Gammaproteobacteria,1YHGK@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_125897_1	983544.Lacal_2377	5.33e-20	85.5	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1HY9V@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_125897_2	313596.RB2501_12919	9.65e-44	144.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1I40R@117743|Flavobacteriia	976|Bacteroidetes	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
k59_37463_1	1168034.FH5T_07050	1.64e-75	226.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_37463_2	1168034.FH5T_07055	2.59e-27	103.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,2FS1V@200643|Bacteroidia	976|Bacteroidetes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_146350_1	1147.D082_11560	3.08e-17	86.3	COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,1H4G7@1142|Synechocystis	1117|Cyanobacteria	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_24127_1	247634.GPB2148_1677	6.73e-22	93.6	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1J58P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2340	AIRS,AIRS_C
k59_24127_2	1126627.BAWE01000004_gene4009	5.84e-23	95.5	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,3JS16@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
k59_207354_1	1168034.FH5T_04005	3.68e-69	219.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_153055_1	396588.Tgr7_3288	1.15e-73	234.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_24128_1	439496.RBY4I_1862	2.41e-109	332.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_207357_1	888059.HMPREF9071_2432	2.56e-98	291.0	COG1662@1|root,COG3677@1|root,COG1662@2|Bacteria,COG3677@2|Bacteria,4NQ2X@976|Bacteroidetes,1I2SR@117743|Flavobacteriia,1ES1K@1016|Capnocytophaga	976|Bacteroidetes	L	Protein involved in DNA binding, transposase activity and transposition, DNA-mediated	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1,HTH_Tnp_IS1,Zn_Tnp_IS1
k59_200518_1	1028801.RG1141_CH20440	1.84e-46	157.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,4BAQU@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_24132_1	1392498.JQLH01000001_gene3251	4.28e-49	177.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI3H@252356|Maribacter	976|Bacteroidetes	S	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD,Sortilin-Vps10,TSP_3
k59_166424_1	754477.Q7C_1704	1.4e-31	122.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,460BE@72273|Thiotrichales	72273|Thiotrichales	EGP	major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_85399_1	2340.JV46_22160	1.48e-05	45.8	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1J4FJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0018995,GO:0022610,GO:0030430,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0050789,GO:0051082,GO:0051704,GO:0061077,GO:0065007,GO:0101031,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_85399_2	2340.JV46_22150	8.32e-55	172.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1J6G0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_4062_1	1165841.SULAR_07193	1.35e-54	176.0	COG2863@1|root,COG2863@2|Bacteria,1Q4WC@1224|Proteobacteria,42NFN@68525|delta/epsilon subdivisions,2YMWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Plasminogen-binding protein pgbA N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PGBA_N
k59_4062_2	1165841.SULAR_07198	1.5e-54	182.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2YMAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycolate oxidase subunit	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_139419_1	1121921.KB898712_gene2146	3.54e-16	82.4	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_125906_1	755732.Fluta_0886	2.5e-24	102.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1I39P@117743|Flavobacteriia,2PBF1@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_207369_1	643473.KB235930_gene3651	1.45e-51	174.0	28PYN@1|root,2ZCI8@2|Bacteria,1G2MM@1117|Cyanobacteria,1HNYC@1161|Nostocales	1117|Cyanobacteria	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
k59_37473_1	1046714.AMRX01000006_gene3063	6.5e-07	51.2	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,464UE@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_37473_2	348780.NP_3196A	3.92e-14	75.1	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,23TI6@183963|Halobacteria	183963|Halobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_58103_1	314231.FP2506_15554	1.93e-28	112.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2PJG1@255475|Aurantimonadaceae	28211|Alphaproteobacteria	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_146374_1	399739.Pmen_2087	5.04e-26	100.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1YCXC@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	rraA	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
k59_146374_2	8469.XP_007065374.1	8.26e-09	56.2	COG1028@1|root,KOG1205@2759|Eukaryota,38HW1@33154|Opisthokonta,3BFJM@33208|Metazoa,3CYPY@33213|Bilateria,483AW@7711|Chordata,491ZK@7742|Vertebrata,4CD5W@8459|Testudines	33208|Metazoa	Q	Dehydrogenase reductase SDR family member 7	DHRS7	-	-	ko:K11165	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
k59_31089_1	768671.ThimaDRAFT_1325	2.88e-14	71.6	COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,1RQ44@1236|Gammaproteobacteria,1X080@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_31089_2	411459.RUMOBE_04035	2.79e-12	67.4	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3Y08K@572511|Blautia	186801|Clostridia	L	Psort location CytoplasmicMembrane, score	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
k59_193764_2	903818.KI912268_gene3366	2.31e-54	175.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
k59_64843_1	331678.Cphamn1_1027	3.63e-68	233.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1FEJP@1090|Chlorobi	1090|Chlorobi	G	glycoside hydrolase, family 65 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
k59_99044_1	439235.Dalk_5087	4.45e-104	313.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_159826_1	1249480.B649_10150	4.59e-16	73.9	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2YPJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k59_159826_2	1165841.SULAR_01608	2.58e-36	126.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC4@68525|delta/epsilon subdivisions,2YMGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_146765_2	882378.RBRH_03065	8.56e-25	97.8	COG0454@1|root,COG0454@2|Bacteria,1RHV9@1224|Proteobacteria,2VQ1X@28216|Betaproteobacteria,1K890@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
k59_214147_1	886377.Murru_0144	2.99e-81	247.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1HWN1@117743|Flavobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
k59_92489_1	324602.Caur_1089	2.25e-08	63.5	COG1572@1|root,COG1572@2|Bacteria,2G7MU@200795|Chloroflexi,374XB@32061|Chloroflexia	32061|Chloroflexia	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k59_24611_1	1279017.AQYJ01000023_gene3226	2.68e-66	207.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,464Y9@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_31466_1	1216007.AOPM01000021_gene3122	2.81e-33	119.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,2Q24U@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_31466_2	1198114.AciX9_2927	1.08e-28	112.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_200803_1	1121374.KB891588_gene3296	2.39e-14	73.9	COG0591@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0591 Na proline symporter	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF
k59_200803_2	247634.GPB2148_2411	6.4e-19	80.1	COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,1S84U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_180313_1	1173027.Mic7113_2675	1.58e-49	179.0	COG0457@1|root,COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
k59_133270_1	272556.CF65_01291	3.32e-110	346.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1Y6SS@135625|Pasteurellales	135625|Pasteurellales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_85802_1	530564.Psta_0510	2.92e-05	51.2	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	pedG	-	-	-	-	-	-	-	-	-	-	-	FMO-like
k59_10887_1	56110.Oscil6304_1052	8.92e-64	221.0	COG0464@1|root,COG0464@2|Bacteria,1G1YA@1117|Cyanobacteria,1H8T6@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_160273_1	1168034.FH5T_01875	4.9e-70	214.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,2FTAK@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG14473 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_17919_1	395493.BegalDRAFT_2175	1.93e-140	435.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,45ZSY@72273|Thiotrichales	72273|Thiotrichales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_51733_1	2340.JV46_17220	2.38e-101	304.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1J50Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	related to Ser Thr protein kinases	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_106155_1	1165841.SULAR_08127	1.01e-22	96.3	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_58563_1	1165841.SULAR_10084	2.12e-137	390.0	COG1845@1|root,COG1845@2|Bacteria,1RI5A@1224|Proteobacteria,43B3F@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_106162_2	1120792.JAFV01000001_gene3437	9.21e-08	53.9	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,37196@31993|Methylocystaceae	28211|Alphaproteobacteria	KT	helix_turn_helix, Lux Regulon	MA20_19670	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_17930_1	344747.PM8797T_12006	3.97e-74	236.0	COG4658@1|root,COG4658@2|Bacteria,2IY8E@203682|Planctomycetes	203682|Planctomycetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	-	-	-	-	-	-	-	-	-	-	NQR2_RnfD_RnfE
k59_17930_2	709991.Odosp_1606	2.86e-15	75.1	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,22XC8@171551|Porphyromonadaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_166800_1	267608.RSp1180	2.12e-30	124.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VNQS@28216|Betaproteobacteria,1K4ZC@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3,HemolysinCabind
k59_194135_1	1173028.ANKO01000077_gene5338	2.27e-37	144.0	COG0515@1|root,COG0642@1|root,COG0784@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,Pkinase,Response_reg
k59_31481_2	1408422.JHYF01000001_gene3061	1.12e-104	319.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,36DRK@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_24632_1	396588.Tgr7_0226	3.81e-98	301.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_10897_1	1165841.SULAR_02433	4.07e-88	267.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_85819_1	1116472.MGMO_11c00610	3.34e-08	54.3	COG3767@1|root,COG3767@2|Bacteria,1QJQT@1224|Proteobacteria,1THS2@1236|Gammaproteobacteria,1XFHU@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85819_2	2340.JV46_12630	1.97e-40	139.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1J5SJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
k59_51756_1	1192034.CAP_6731	4.92e-29	119.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42Y66@68525|delta/epsilon subdivisions,2WU83@28221|Deltaproteobacteria,2YX71@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_10898_1	1165841.SULAR_09284	1.16e-45	153.0	COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,42N9F@68525|delta/epsilon subdivisions,2YNBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
k59_85820_1	1165841.SULAR_01718	1.6e-84	260.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1N68I@1224|Proteobacteria,43BAI@68525|delta/epsilon subdivisions,2YT7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_160292_1	1218084.BBJK01000016_gene1640	2.93e-05	48.5	28JPA@1|root,2Z9FC@2|Bacteria,1PN1F@1224|Proteobacteria,2VMSI@28216|Betaproteobacteria,1K3QT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160292_2	1121405.dsmv_2663	1.49e-07	53.1	COG0644@1|root,COG0644@2|Bacteria,1NRHS@1224|Proteobacteria,42Z9T@68525|delta/epsilon subdivisions,2WUMT@28221|Deltaproteobacteria,2MMGQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14909_1	794903.OPIT5_07185	6.62e-25	109.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,46V2T@74201|Verrucomicrobia,3K9RQ@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
k59_157216_1	1168034.FH5T_18230	4.65e-86	267.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FNCD@200643|Bacteroidia	976|Bacteroidetes	I	Carboxyl transferase domain protein	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_1360_1	1165841.SULAR_06093	1.22e-72	219.0	COG2905@1|root,COG2905@2|Bacteria,1RI05@1224|Proteobacteria,43BDH@68525|delta/epsilon subdivisions,2YPVH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1360_2	387093.SUN_1868	3.45e-30	116.0	COG0642@1|root,COG2205@2|Bacteria,1QZNK@1224|Proteobacteria,42R3C@68525|delta/epsilon subdivisions,2YP1R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_8003_1	697282.Mettu_1766	1.57e-94	295.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XEF1@135618|Methylococcales	135618|Methylococcales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_89567_2	395493.BegalDRAFT_1628	3.89e-58	188.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,1S0X4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	nifY	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
k59_103025_1	102125.Xen7305DRAFT_00012670	5.93e-62	214.0	COG0515@1|root,COG2199@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GHRX@1117|Cyanobacteria,3VHRW@52604|Pleurocapsales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,Pkinase
k59_150449_1	203119.Cthe_3123	5.34e-07	57.4	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
k59_143557_1	313596.RB2501_03195	1.67e-83	253.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_177449_1	1195246.AGRI_12781	8.36e-75	256.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4645Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_75764_1	395493.BegalDRAFT_2485	4.45e-27	114.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_157225_1	765914.ThisiDRAFT_2254	2.57e-79	255.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales	135613|Chromatiales	I	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_8007_1	1397699.JNIS01000001_gene1613	3.55e-109	335.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3WE1E@539002|Bacillales incertae sedis	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_211576_1	402881.Plav_3625	2.64e-17	81.6	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,1JP0H@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	RimP C-terminal SH3 domain	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_75765_1	1121370.AQUY01000001_gene495	1.13e-09	61.2	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,22MNF@1653|Corynebacteriaceae	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_8010_1	1121022.ABENE_05900	1.66e-55	184.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,2TU3Y@28211|Alphaproteobacteria,2KFIE@204458|Caulobacterales	204458|Caulobacterales	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
k59_197981_1	1121904.ARBP01000007_gene2888	2.8e-67	233.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,47MF6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_157234_1	335543.Sfum_0279	7.35e-18	83.2	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_163921_2	1129794.C427_4693	6.44e-76	236.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,469JR@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_163921_3	1121035.AUCH01000004_gene429	1.34e-05	46.6	COG1924@1|root,COG1924@2|Bacteria,1PKG6@1224|Proteobacteria	1224|Proteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
k59_69054_1	469381.Dpep_1798	1.59e-25	110.0	COG0642@1|root,COG0642@2|Bacteria,3T9SP@508458|Synergistetes	508458|Synergistetes	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,SBP_bac_3
k59_109800_1	1347342.BN863_31600	1.19e-49	177.0	COG0574@1|root,COG0574@2|Bacteria,4NH4R@976|Bacteroidetes,1HWKY@117743|Flavobacteriia	976|Bacteroidetes	G	Pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_109800_2	1121011.AUCB01000009_gene1907	5.47e-07	51.2	COG2367@1|root,COG2367@2|Bacteria,4NHF9@976|Bacteroidetes,1HZHM@117743|Flavobacteriia,23GV7@178469|Arenibacter	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
k59_116730_1	7029.ACYPI071932-PA	1.95e-12	71.6	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1758,DUF1759,Peptidase_A17,rve
k59_55605_1	1165841.SULAR_01445	8.06e-98	298.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DEAD DEAH box helicase	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_42458_1	1165841.SULAR_05733	2.14e-29	113.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_42458_2	1165841.SULAR_05728	4.5e-20	83.6	COG0711@1|root,COG0711@2|Bacteria,1Q2G9@1224|Proteobacteria,42VN4@68525|delta/epsilon subdivisions,2YQBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the ATPase B chain family	atpF'	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_22231_1	1168034.FH5T_18935	4.59e-104	320.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,2FQB7@200643|Bacteroidia	976|Bacteroidetes	C	dehydrogenase E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_191680_1	1168034.FH5T_06970	3.81e-16	79.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,2FSM8@200643|Bacteroidia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
k59_150983_1	443255.SCLAV_5689	2.68e-128	377.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_198609_1	635013.TherJR_0119	0.000244	48.9	COG3391@1|root,COG3391@2|Bacteria,1UW22@1239|Firmicutes,24W73@186801|Clostridia,266DU@186807|Peptococcaceae	186801|Clostridia	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
k59_42462_1	387093.SUN_0164	4.84e-49	160.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42RJW@68525|delta/epsilon subdivisions,2YP85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_56057_1	1121920.AUAU01000004_gene805	5.2e-26	107.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,3Y578@57723|Acidobacteria	57723|Acidobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
k59_144014_2	2340.JV46_24180	1.75e-06	48.1	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1J50E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_22235_1	243233.MCA2447	3.22e-41	155.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XDRZ@135618|Methylococcales	135618|Methylococcales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_96831_1	29760.VIT_00s0246g00230.t01	1.07e-39	144.0	2C63X@1|root,2S2ZC@2759|Eukaryota,37VFD@33090|Viridiplantae,3GJPI@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1954_1	313596.RB2501_05520	2.14e-149	442.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1HXDK@117743|Flavobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
k59_8495_2	1122212.AULO01000007_gene2498	1.3e-74	229.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,1XIB2@135619|Oceanospirillales	135619|Oceanospirillales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_15474_1	1165841.SULAR_01280	5.53e-41	139.0	COG0778@1|root,COG0778@2|Bacteria,1RFM9@1224|Proteobacteria,43AKB@68525|delta/epsilon subdivisions,2YT1P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_15474_2	1165841.SULAR_01285	2.58e-112	323.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42RJP@68525|delta/epsilon subdivisions,2YP82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1881 Phospholipid-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k59_15474_3	1165841.SULAR_01290	8.38e-46	150.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2YQHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	protein involved in tolerance to divalent cations	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k59_35661_1	1123326.JFBL01000010_gene747	1.02e-95	294.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_110351_1	583355.Caka_2195	4.76e-114	341.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_22241_1	637905.SVI_2664	2.22e-06	55.5	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,2QBEV@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16087,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10,1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_62953_1	177437.HRM2_45150	5.05e-14	77.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria,2MJ8W@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_8497_1	886377.Murru_0263	3.26e-60	192.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1HXY3@117743|Flavobacteriia	976|Bacteroidetes	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
k59_8497_2	867900.Celly_0261	9.48e-25	100.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1HX8P@117743|Flavobacteriia,1F8V8@104264|Cellulophaga	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
k59_96838_1	1535422.ND16A_2148	2.34e-17	82.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,2Q7V3@267889|Colwelliaceae	1236|Gammaproteobacteria	U	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_157913_1	1095769.CAHF01000022_gene432	9.86e-100	328.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_29140_1	65093.PCC7418_2970	2.21e-36	126.0	COG1487@1|root,COG1487@2|Bacteria,1G6RD@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
k59_110358_1	105559.Nwat_2049	7.37e-23	101.0	COG3857@1|root,COG3857@2|Bacteria,1QUQD@1224|Proteobacteria,1T20Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_123841_1	1121937.AUHJ01000007_gene1956	1.34e-51	171.0	2DBQY@1|root,2ZAHD@2|Bacteria,1QYTK@1224|Proteobacteria,1T3V2@1236|Gammaproteobacteria,46DA3@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_69710_1	234267.Acid_2266	3.08e-51	182.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
k59_90142_1	396588.Tgr7_3185	1.38e-84	274.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_205215_1	1266909.AUAG01000022_gene1682	9.93e-47	168.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_76375_1	4081.Solyc11g062200.1.1	3.69e-65	223.0	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae,3GG2K@35493|Streptophyta,44UC5@71274|asterids	35493|Streptophyta	L	Mitochondrial protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve,zf-CCHC
k59_171388_1	1304880.JAGB01000001_gene826	3.07e-38	137.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia	186801|Clostridia	J	Pseudouridine synthase	rluC	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_29148_1	1165841.SULAR_05193	1.75e-83	272.0	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_164527_1	1165841.SULAR_09569	2.1e-94	286.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_110368_1	1283300.ATXB01000001_gene752	1.23e-124	368.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XE4Y@135618|Methylococcales	135618|Methylococcales	C	Glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_69719_1	1085623.GNIT_0194	7.91e-61	214.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,465ZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_212072_1	493475.GARC_0322	6.24e-48	172.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,465CD@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_103603_1	1141106.CAIB01000182_gene1788	2.82e-34	130.0	COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,4HC2H@91061|Bacilli,4GZUE@90964|Staphylococcaceae	91061|Bacilli	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_11553_2	1123399.AQVE01000002_gene2456	3.97e-32	114.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,462Y1@72273|Thiotrichales	72273|Thiotrichales	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_147426_2	376686.Fjoh_2163	2.75e-12	68.6	arCOG10603@1|root,32SV6@2|Bacteria,4NTSF@976|Bacteroidetes,1IJ36@117743|Flavobacteriia,2NS7J@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45553_1	1536773.R70331_05815	3.96e-11	62.4	COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,26YKY@186822|Paenibacillaceae	91061|Bacilli	S	Thiol-disulfide oxidoreductase DCC	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
k59_194832_1	1042375.AFPL01000026_gene3624	2.25e-21	87.4	2E4CK@1|root,32Z81@2|Bacteria,1N7JR@1224|Proteobacteria,1SCEZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	With PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone	pqqD	-	-	ko:K06138	-	-	-	-	ko00000	-	-	-	PqqD
k59_194832_2	765913.ThidrDRAFT_0529	8.62e-65	208.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1WWJ4@135613|Chromatiales	135613|Chromatiales	S	Radical SAM superfamily	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_112942_1	84531.JMTZ01000044_gene965	7.17e-68	218.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1X9GG@135614|Xanthomonadales	135614|Xanthomonadales	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_112942_2	511145.b4475	3.88e-38	137.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria,3XMP7@561|Escherichia	1236|Gammaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
k59_214763_1	1168034.FH5T_14810	2.79e-13	64.3	COG0526@1|root,COG0526@2|Bacteria,4NUP1@976|Bacteroidetes,2FUJZ@200643|Bacteroidia	976|Bacteroidetes	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k59_52325_1	1165841.SULAR_08487	7.67e-183	514.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_167542_1	2340.JV46_16920	2.6e-74	233.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_45559_1	1165841.SULAR_07585	6.69e-59	200.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_45559_2	1165841.SULAR_07580	4.31e-57	186.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2YMNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_93217_1	391625.PPSIR1_05023	8.12e-46	167.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,42PAS@68525|delta/epsilon subdivisions,2WX02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_147918_2	1195236.CTER_5384	0.000236	46.6	COG3386@1|root,COG3386@2|Bacteria,1UQYB@1239|Firmicutes,250RJ@186801|Clostridia	186801|Clostridia	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
k59_161403_1	1177179.A11A3_17167	1.99e-145	415.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1XNN8@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_208805_1	555778.Hneap_0880	1.62e-62	201.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1WWXT@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_208805_2	33905.BTHE_0904	1.47e-08	52.4	COG0393@1|root,COG0393@2|Bacteria,2IQNY@201174|Actinobacteria,4D0ZM@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
k59_79906_1	498848.TaqDRAFT_3533	3.21e-21	98.6	COG0569@1|root,COG0569@2|Bacteria,1WITK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	COG0569 K transport systems NAD-binding component	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_25623_1	1121374.KB891575_gene1462	8.74e-19	83.6	COG0625@1|root,COG0625@2|Bacteria,1RAIN@1224|Proteobacteria,1S3Q5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
k59_25623_2	398578.Daci_5761	8.75e-31	114.0	COG5113@1|root,COG3236@2|Bacteria,1RCXE@1224|Proteobacteria,2VRRD@28216|Betaproteobacteria,4AE7G@80864|Comamonadaceae	28216|Betaproteobacteria	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
k59_5730_1	1121405.dsmv_0890	8.22e-40	145.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MIDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein)	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_5730_2	1121405.dsmv_0889	1.99e-89	269.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NRE@68525|delta/epsilon subdivisions,2WM0E@28221|Deltaproteobacteria,2MJFH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_32570_1	1165841.SULAR_04893	1.14e-86	261.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2YN03@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_208808_1	1163409.UUA_02186	1.01e-68	227.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,1X4EX@135614|Xanthomonadales	135614|Xanthomonadales	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
k59_181480_1	1265313.HRUBRA_02452	9.27e-24	98.6	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_181480_2	1397527.Q670_09870	3.09e-24	96.3	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1XK9R@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
k59_38869_1	313596.RB2501_06835	1.43e-119	350.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_161411_2	688269.Theth_0649	7.66e-05	48.1	COG0845@1|root,COG0845@2|Bacteria,2GD8D@200918|Thermotogae	200918|Thermotogae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_188324_2	4098.XP_009605876.1	1.34e-13	71.2	COG2801@1|root,KOG0017@2759|Eukaryota,38889@33090|Viridiplantae,3GZ32@35493|Streptophyta,44TWH@71274|asterids	35493|Streptophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_3
k59_59779_1	472759.Nhal_1098	7.65e-94	285.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_19177_1	1089551.KE386572_gene4747	9.11e-19	82.4	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,2UBXI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
k59_208810_1	1165841.SULAR_09944	9.65e-205	581.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_5739_1	247633.GP2143_08254	2.81e-54	177.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1J5Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_120866_1	1100720.ALKN01000017_gene1712	3.68e-31	117.0	COG2963@1|root,COG2963@2|Bacteria,1RIC7@1224|Proteobacteria,2VTQ4@28216|Betaproteobacteria,4AJRS@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_120866_2	1485545.JQLW01000010_gene1491	9.73e-132	387.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32,rve,rve_3
k59_181484_1	1165841.SULAR_09099	5.25e-100	294.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,42NNI@68525|delta/epsilon subdivisions,2YNBH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,Methyltransf_31
k59_181484_2	1165841.SULAR_09109	1.17e-123	358.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_25637_1	1165841.SULAR_05648	4.95e-83	260.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	glnL	-	-	ko:K07719	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,TPR_16,TPR_19,TPR_8,YcbB
k59_93714_1	675812.VHA_000873	9.06e-13	76.3	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XTE5@135623|Vibrionales	135623|Vibrionales	D	protein involved in exopolysaccharide biosynthesis	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
k59_168118_1	395493.BegalDRAFT_0867	9.27e-80	251.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,460BC@72273|Thiotrichales	72273|Thiotrichales	Q	transporter, dctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_140847_1	1165841.SULAR_05603	3.41e-05	45.1	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2YMR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_140847_2	1165841.SULAR_05598	1.32e-80	243.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2YT9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_174854_1	1298865.H978DRAFT_2952	1.11e-19	80.5	2C16Q@1|root,330H3@2|Bacteria,1NB82@1224|Proteobacteria,1SERQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
k59_174854_2	1173026.Glo7428_1788	2.31e-45	150.0	COG1569@1|root,COG1569@2|Bacteria,1G5T4@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxin-antitoxin system, toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_161417_1	1165841.SULAR_09659	1.88e-139	419.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_32589_1	387093.SUN_1625	3.19e-64	209.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
k59_107396_1	395493.BegalDRAFT_1821	8.82e-79	243.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,4605X@72273|Thiotrichales	72273|Thiotrichales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_52802_1	1095769.CAHF01000022_gene432	4.24e-137	442.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_38898_1	1198232.CYCME_2326	2.26e-81	254.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,4601D@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_154488_1	102129.Lepto7375DRAFT_0843	2.96e-40	156.0	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_25658_1	56110.Oscil6304_0730	6.89e-105	322.0	COG1132@1|root,COG1132@2|Bacteria,1G0C0@1117|Cyanobacteria,1H8B0@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
k59_86805_1	313590.MED134_07706	9.02e-40	142.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia,37DX4@326319|Dokdonia	976|Bacteroidetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_86805_2	1454007.JAUG01000016_gene1763	3.29e-05	46.2	COG3577@1|root,COG3577@2|Bacteria,4PIW5@976|Bacteroidetes,1IYRC@117747|Sphingobacteriia	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
k59_188335_1	1125973.JNLC01000015_gene3449	4.1e-33	128.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,3JSFN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase muconate lactonizing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
k59_134424_1	1523503.JPMY01000046_gene1379	9.28e-18	87.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_38906_1	1123035.ARLA01000025_gene1522	1.96e-31	116.0	2DC7W@1|root,2ZD7C@2|Bacteria,4NMMW@976|Bacteroidetes,1I1HS@117743|Flavobacteriia,4C3SI@83612|Psychroflexus	976|Bacteroidetes	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k59_38906_2	1046724.KB889918_gene261	1.11e-15	74.7	COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,467KI@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Anti-ECFsigma factor ChrR	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
k59_208824_1	1165841.SULAR_06148	7.52e-113	325.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2YNXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_208824_2	1165841.SULAR_06153	1.37e-58	181.0	COG4627@1|root,COG4627@2|Bacteria,1NHR6@1224|Proteobacteria,42VA4@68525|delta/epsilon subdivisions,2YQEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Stress responsive A B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
k59_208824_3	387093.SUN_1879	2.75e-40	142.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_168137_1	1168034.FH5T_08900	1.96e-77	238.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,2FP5N@200643|Bacteroidia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_168137_2	1392838.AWNM01000016_gene3301	5.97e-17	84.3	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,2VRHM@28216|Betaproteobacteria,3T98X@506|Alcaligenaceae	28216|Betaproteobacteria	CG	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
k59_19183_2	2340.JV46_23650	6.01e-105	316.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1J4PB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_140873_1	1123487.KB892865_gene1391	5.75e-64	211.0	COG0553@1|root,COG0553@2|Bacteria,1PN7I@1224|Proteobacteria,2VP2N@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	SNF2_N
k59_195333_1	502025.Hoch_2925	1.69e-81	290.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria,2YYJV@29|Myxococcales	28221|Deltaproteobacteria	M	Rhs family	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN,Tox-PL-2,VCBS,ZU5
k59_100349_1	1165841.SULAR_04167	1.37e-110	330.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_59817_1	886293.Sinac_2583	2.15e-05	49.7	COG2010@1|root,COG2010@2|Bacteria,2IYHH@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
k59_12064_1	1168034.FH5T_04785	1.94e-121	355.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,2FP71@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_38914_1	203275.BFO_3001	8.03e-121	351.0	COG3677@1|root,COG3677@2|Bacteria,4NHYS@976|Bacteroidetes,2FPPS@200643|Bacteroidia,22XK1@171551|Porphyromonadaceae	976|Bacteroidetes	L	SPTR Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_25672_1	1168067.JAGP01000001_gene913	5.21e-28	112.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,1S8D0@1236|Gammaproteobacteria,462RF@72273|Thiotrichales	72273|Thiotrichales	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_137685_1	497964.CfE428DRAFT_4943	1.08e-29	120.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_56408_1	448385.sce8000	1.76e-78	250.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_42787_1	56780.SYN_02552	6.07e-34	135.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria,2MQZ8@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	UvrD/REP helicase N-terminal domain	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_178311_2	1123228.AUIH01000131_gene2866	3.88e-61	204.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1XS1N@135619|Oceanospirillales	135619|Oceanospirillales	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_192061_1	1165841.SULAR_09169	3.07e-108	319.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2YMCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_151306_1	765912.Thimo_3284	5.11e-72	226.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1WWPW@135613|Chromatiales	135613|Chromatiales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_50290_1	1049564.TevJSym_ai00190	3.66e-71	223.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1J5AA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_104328_1	489825.LYNGBM3L_40620	2.71e-60	201.0	COG0025@1|root,COG0025@2|Bacteria,1G2G9@1117|Cyanobacteria,1HDEQ@1150|Oscillatoriales	1117|Cyanobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_172071_1	1396141.BATP01000019_gene1580	1.14e-20	95.1	COG0526@1|root,COG0526@2|Bacteria,46VHM@74201|Verrucomicrobia,2IVZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_77180_1	1517681.HW45_17765	1.82e-49	167.0	COG0582@1|root,COG0582@2|Bacteria,1QUFZ@1224|Proteobacteria,1T1XN@1236|Gammaproteobacteria,1XUVH@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	intIA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_2746_1	1254432.SCE1572_13245	5.8e-37	143.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2X4FQ@28221|Deltaproteobacteria,2YYXH@29|Myxococcales	28221|Deltaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_23,PP-binding
k59_206053_1	370438.PTH_1610	2.28e-57	192.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
k59_29816_1	768671.ThimaDRAFT_0329	2.63e-17	80.5	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,1S09K@1236|Gammaproteobacteria,1WX6Q@135613|Chromatiales	135613|Chromatiales	S	PFAM DMSO reductase anchor subunit (DmsC)	-	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
k59_29816_2	2340.JV46_27590	6.29e-163	457.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1J9UJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7,Molydop_binding
k59_165165_1	768671.ThimaDRAFT_3563	1.42e-67	227.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXY0@135613|Chromatiales	135613|Chromatiales	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
k59_70346_1	387093.SUN_1510	3.3e-226	639.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_144877_1	270374.MELB17_22535	6.83e-110	332.0	COG4467@1|root,COG4467@2|Bacteria,1QW8C@1224|Proteobacteria,1S2JX@1236|Gammaproteobacteria,46BUT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_90903_1	929562.Emtol_4126	2.22e-32	120.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,47K99@768503|Cytophagia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_185508_1	4081.Solyc00g021640.2.1	3.77e-204	572.0	28P22@1|root,2QVNI@2759|Eukaryota,37SGH@33090|Viridiplantae,3GFX8@35493|Streptophyta	35493|Streptophyta	S	ribosomal protein S4	-	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
k59_165166_1	870187.Thini_1247	3.48e-101	301.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,1RNHT@1236|Gammaproteobacteria,462FM@72273|Thiotrichales	72273|Thiotrichales	C	MauM NapG family ferredoxin-type protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_22887_1	1169144.KB910965_gene3039	9.2e-07	50.1	COG1969@1|root,COG1969@2|Bacteria,1UYHW@1239|Firmicutes,4HDEE@91061|Bacilli,1ZDZD@1386|Bacillus	91061|Bacilli	C	Domain of unknown function (DUF4405)	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	HycI,Ni_hydr_CYTB
k59_22887_2	991.IW20_03690	7.98e-61	202.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1I3BR@117743|Flavobacteriia,2NYJF@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_84044_1	1165841.SULAR_05898	1.01e-112	353.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_206069_1	1168034.FH5T_20545	1.71e-123	369.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,2FX28@200643|Bacteroidia	976|Bacteroidetes	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_77200_1	706587.Desti_1791	4.16e-07	57.0	COG0726@1|root,COG3391@1|root,COG0726@2|Bacteria,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS
k59_118040_1	1168034.FH5T_18945	2.68e-48	167.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,2FMC4@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_118040_2	1168034.FH5T_18950	6.72e-15	75.5	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_206070_1	98439.AJLL01000025_gene215	2.65e-31	115.0	COG1569@1|root,COG1569@2|Bacteria,1G5T4@1117|Cyanobacteria,1JIHH@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_70365_1	717774.Marme_3282	1.06e-30	115.0	COG1215@1|root,COG1215@2|Bacteria,1R6YR@1224|Proteobacteria,1RRS4@1236|Gammaproteobacteria,1XRYQ@135619|Oceanospirillales	135619|Oceanospirillales	M	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_70365_2	1167006.UWK_02363	7.54e-28	111.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria,2MI8V@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_165182_1	469617.FUAG_01691	3.32e-05	47.0	COG0461@1|root,COG0461@2|Bacteria,3790D@32066|Fusobacteria	32066|Fusobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_151753_1	870187.Thini_0563	6.89e-75	249.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,1T1AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_2757_1	396588.Tgr7_2064	2.26e-26	102.0	2DXWD@1|root,346YK@2|Bacteria,1P0D0@1224|Proteobacteria,1SRBF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2757_2	2340.JV46_27310	1.35e-05	47.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1J5T6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	ThiF family	ygdL	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k59_56793_2	1118153.MOY_08082	1.54e-12	69.3	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,1XIRQ@135619|Oceanospirillales	135619|Oceanospirillales	L	EcoEI R protein C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,Helicase_C,ResIII
k59_206076_2	1168034.FH5T_05385	4.87e-69	213.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_9440_1	43989.cce_2208	3.47e-16	75.5	COG1853@1|root,COG1853@2|Bacteria,1G4QZ@1117|Cyanobacteria,3KGJX@43988|Cyanothece	1117|Cyanobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_77214_1	1121405.dsmv_0168	1.22e-68	212.0	2CA4A@1|root,32RQK@2|Bacteria,1RE4A@1224|Proteobacteria,42RRI@68525|delta/epsilon subdivisions,2WND4@28221|Deltaproteobacteria,2MJUU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
k59_144920_1	1123399.AQVE01000013_gene312	5.11e-40	138.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,460WR@72273|Thiotrichales	72273|Thiotrichales	S	Fe-S metabolism associated domain	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k59_212723_1	46234.ANA_C11804	3.14e-53	192.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_25,PP-binding,Thioesterase
k59_144923_1	666681.M301_0477	1.04e-08	58.9	COG2834@1|root,COG2834@2|Bacteria,1R8JU@1224|Proteobacteria,2VPQR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_22917_1	2340.JV46_11270	1.79e-111	325.0	COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1J5KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3412,iSDY_1059.SDY_0027	AdoMet_dc
k59_70377_1	1184607.AUCHE_05_02670	3.61e-14	72.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4F6WJ@85018|Dermatophilaceae	201174|Actinobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	preT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
k59_165191_1	1278307.KB907072_gene2701	1.15e-144	414.0	COG1637@1|root,COG1637@2|Bacteria	2|Bacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
k59_212727_1	1122201.AUAZ01000022_gene3082	1.41e-117	342.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,1RR82@1236|Gammaproteobacteria,466BC@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k59_2775_1	395493.BegalDRAFT_2997	4.43e-43	154.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,45ZX6@72273|Thiotrichales	72273|Thiotrichales	S	AI-2E family transporter	-	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
k59_84068_1	1047013.AQSP01000122_gene2249	8.67e-112	340.0	28NDD@1|root,2ZBG6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_192468_1	880070.Cycma_0163	1.21e-42	149.0	COG3828@1|root,COG3828@2|Bacteria,4PNCT@976|Bacteroidetes,47YBZ@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
k59_185556_1	756067.MicvaDRAFT_2896	4.08e-26	111.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H7QZ@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_70387_1	1123368.AUIS01000031_gene1418	6.25e-83	256.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,1T8C8@1236|Gammaproteobacteria,2NCKI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_212732_1	313596.RB2501_00321	1.76e-27	111.0	COG1208@1|root,COG1208@2|Bacteria,4PM6W@976|Bacteroidetes,1IJJT@117743|Flavobacteriia	976|Bacteroidetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,NTP_transf_4
k59_212732_2	886377.Murru_0085	2.85e-27	100.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1I3YC@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL31 family	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_206091_1	357804.Ping_0681	3.7e-30	110.0	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria,2QJ4R@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11022	ko05134,map05134	-	-	-	ko00000,ko00001,ko02042	-	-	-	-
k59_206091_2	1236501.BAJU01000010_gene1417	7.85e-12	66.2	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,2JPNG@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_165195_1	1195246.AGRI_10286	9.93e-06	48.9	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,46612@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313	Inositol_P
k59_192470_1	335543.Sfum_2777	1.78e-49	177.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MQ89@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
k59_185561_1	879212.DespoDRAFT_01813	3.6e-11	62.4	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,2MJUG@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_185561_2	1123073.KB899243_gene466	3.59e-60	198.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1X3X4@135614|Xanthomonadales	135614|Xanthomonadales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_104360_1	395493.BegalDRAFT_1194	1.2e-83	258.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RVJU@1236|Gammaproteobacteria,461VP@72273|Thiotrichales	72273|Thiotrichales	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_124640_1	45351.EDO46109	1.6e-26	112.0	KOG0621@1|root,KOG0621@2759|Eukaryota,38I3R@33154|Opisthokonta,3BBDE@33208|Metazoa	33208|Metazoa	M	phospholipid scrambling	PLSCR3	GO:0000981,GO:0000982,GO:0001077,GO:0001228,GO:0001775,GO:0002237,GO:0002252,GO:0002376,GO:0002520,GO:0002526,GO:0002682,GO:0002684,GO:0002694,GO:0003674,GO:0003700,GO:0005102,GO:0005154,GO:0005215,GO:0005319,GO:0005488,GO:0005509,GO:0005515,GO:0005548,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005794,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006575,GO:0006629,GO:0006644,GO:0006650,GO:0006658,GO:0006659,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006915,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0006955,GO:0007009,GO:0007154,GO:0007165,GO:0007275,GO:0007596,GO:0007599,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009611,GO:0009615,GO:0009617,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010256,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010876,GO:0010911,GO:0010912,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0015711,GO:0015748,GO:0015914,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0017121,GO:0017124,GO:0017128,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019899,GO:0019904,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030168,GO:0031012,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031974,GO:0031981,GO:0032091,GO:0032496,GO:0032501,GO:0032502,GO:0032774,GO:0032781,GO:0033003,GO:0033036,GO:0033500,GO:0033993,GO:0034097,GO:0034641,GO:0034645,GO:0034654,GO:0035455,GO:0035456,GO:0035556,GO:0042060,GO:0042221,GO:0042398,GO:0042592,GO:0042593,GO:0042609,GO:0042632,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043462,GO:0043900,GO:0043901,GO:0043903,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044271,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045017,GO:0045069,GO:0045071,GO:0045088,GO:0045089,GO:0045121,GO:0045893,GO:0045935,GO:0045944,GO:0046474,GO:0046483,GO:0046486,GO:0046872,GO:0048306,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048525,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050817,GO:0050865,GO:0050878,GO:0050896,GO:0051098,GO:0051100,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051254,GO:0051336,GO:0051345,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055088,GO:0055092,GO:0060255,GO:0060368,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070782,GO:0070851,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071396,GO:0071702,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090407,GO:0097035,GO:0097190,GO:0097193,GO:0097194,GO:0097659,GO:0098542,GO:0098589,GO:0098805,GO:0098857,GO:0140110,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701,GO:1902229,GO:1902231,GO:1902531,GO:1902533,GO:1902680,GO:1903506,GO:1903508,GO:1903900,GO:1903901,GO:2000112,GO:2000371,GO:2000373,GO:2001020,GO:2001022,GO:2001141,GO:2001233,GO:2001235,GO:2001242,GO:2001244	-	-	-	-	-	-	-	-	-	-	Scramblase
k59_43228_1	305900.GV64_14130	2.16e-108	336.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1XHDB@135619|Oceanospirillales	135619|Oceanospirillales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.117	ko:K20455	ko00640,map00640	-	R11263	RC01152	ko00000,ko00001,ko01000	-	-	-	Aconitase,Aconitase_C
k59_165196_1	575540.Isop_3064	1.22e-22	103.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_111044_1	1242864.D187_010405	4.65e-80	253.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42ZA9@68525|delta/epsilon subdivisions,2WU3B@28221|Deltaproteobacteria,2YU7S@29|Myxococcales	28221|Deltaproteobacteria	KT	GAF domain	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GAF_3,HTH_8,Sigma54_activat
k59_97773_1	1165841.SULAR_01160	2.77e-103	308.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,42PT0@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_104363_1	1348663.KCH_21330	2.95e-06	49.7	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	ko:K08365,ko:K13640,ko:K18997,ko:K19057	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_17,MerR_1,MerR_2
k59_192473_1	518766.Rmar_0494	2.55e-103	311.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1FIQT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_50325_1	1249627.D779_0897	1.36e-44	159.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RPAZ@1236|Gammaproteobacteria,1WWIG@135613|Chromatiales	135613|Chromatiales	G	PFAM Ribulose bisphosphate carboxylase large	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large
k59_199404_1	1165841.SULAR_05583	2.56e-16	75.5	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2YMCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_199404_2	1165841.SULAR_05578	2.14e-38	128.0	COG1758@1|root,COG1758@2|Bacteria,1Q28G@1224|Proteobacteria,42V5Z@68525|delta/epsilon subdivisions,2YQDH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_199404_3	1165841.SULAR_05573	8.09e-45	160.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_80862_1	1049564.TevJSym_aa01810	4.24e-41	150.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1J8SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Citrate transporter	sac1	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_202863_1	115991.K0NZW4_9CAUD	7.95e-28	119.0	4QHQV@10239|Viruses,4QX6C@35237|dsDNA viruses  no RNA stage,4QRJ7@28883|Caudovirales,4QIJU@10662|Myoviridae	10662|Myoviridae	S	virus tail assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6575_1	713587.THITH_13040	1.33e-18	85.1	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales	135613|Chromatiales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_6575_2	999141.GME_12539	1.46e-59	188.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1XJHQ@135619|Oceanospirillales	135619|Oceanospirillales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_39787_1	1122185.N792_10940	2.44e-08	52.8	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1X7UU@135614|Xanthomonadales	135614|Xanthomonadales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
k59_39787_2	1249627.D779_0049	5.67e-72	234.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_94552_1	1209072.ALBT01000076_gene69	7.44e-08	54.7	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1FGFM@10|Cellvibrio	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	rhdA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_94552_2	2340.JV46_07950	1.94e-70	223.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,1J4QK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	pucG	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_73686_1	744872.Spica_1249	1.14e-37	145.0	COG1205@1|root,COG1205@2|Bacteria,2J5DK@203691|Spirochaetes	203691|Spirochaetes	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
k59_67538_1	1165841.SULAR_05178	4.4e-33	118.0	COG2834@1|root,COG2834@2|Bacteria,1PQ15@1224|Proteobacteria,42WEH@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_67538_2	1165841.SULAR_05173	3e-52	180.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_188871_1	1168034.FH5T_11685	4.53e-38	139.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,2FQ4K@200643|Bacteroidia	976|Bacteroidetes	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_26640_2	113355.CM001775_gene3659	2.83e-51	166.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_19971_1	313603.FB2170_12856	6.01e-75	233.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,1IJ8P@117743|Flavobacteriia,2PGKG@252356|Maribacter	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_182428_2	631362.Thi970DRAFT_01150	1.21e-29	114.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWVI@135613|Chromatiales	135613|Chromatiales	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_108295_1	1408823.AXUS01000022_gene2402	1.35e-07	55.1	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,25TQP@186804|Peptostreptococcaceae	186801|Clostridia	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_188876_2	1392498.JQLH01000001_gene1042	1.9e-62	194.0	COG3564@1|root,COG3564@2|Bacteria,4NQEN@976|Bacteroidetes,1I2VZ@117743|Flavobacteriia,2PIP0@252356|Maribacter	976|Bacteroidetes	S	Protein of unknown function (DUF779)	-	-	-	ko:K09959	-	-	-	-	ko00000	-	-	-	DUF779
k59_169131_1	1469557.JSWF01000044_gene667	3.27e-69	218.0	2EP6X@1|root,33GTN@2|Bacteria,4NXH1@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF3575)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
k59_188880_1	1168034.FH5T_05590	3.97e-107	333.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,2FN1R@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_39806_1	1589297.A0A0B5H2N3_9CAUD	2.46e-77	238.0	4QEMD@10239|Viruses,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae	10744|Podoviridae	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_47090_1	313596.RB2501_11557	5.02e-20	87.8	COG0392@1|root,COG0392@2|Bacteria,4NMZ1@976|Bacteroidetes,1I0GR@117743|Flavobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_47090_2	313596.RB2501_11562	1.36e-79	244.0	COG0463@1|root,COG0463@2|Bacteria,4PMAN@976|Bacteroidetes,1IJPP@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_175892_1	243233.MCA1429	2.04e-24	104.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1QY3G@1224|Proteobacteria,1SN4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73696_1	1165841.SULAR_03462	1.8e-35	131.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2YNSP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k59_73696_2	598659.NAMH_0766	5.55e-42	153.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2YMT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_196094_1	667015.Bacsa_2096	1.11e-61	204.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,2FNXZ@200643|Bacteroidia,4APGM@815|Bacteroidaceae	976|Bacteroidetes	P	COG2382 Enterochelin esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
k59_87717_2	566461.SSFG_07877	1.44e-22	100.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_121689_1	640511.BC1002_2556	1.56e-56	187.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,1K09V@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_13100_1	1287276.X752_26315	1.23e-33	127.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2TS3I@28211|Alphaproteobacteria,43HH4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC transporter	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_19986_1	1121918.ARWE01000001_gene1055	3.09e-28	119.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,43S1R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	RecF/RecN/SMC N terminal domain	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_175896_1	448385.sce8257	1.6e-61	215.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria	1224|Proteobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_135164_1	1408473.JHXO01000005_gene1855	1.3e-51	165.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia	976|Bacteroidetes	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k59_196117_1	365044.Pnap_1956	6.03e-27	113.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4AD9I@80864|Comamonadaceae	28216|Betaproteobacteria	T	Sigma-54 interaction domain	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_108327_1	1162668.LFE_0875	1.01e-109	353.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_13116_1	1165841.SULAR_06823	2.93e-16	75.5	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42MTC@68525|delta/epsilon subdivisions,2YMSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cosR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_13116_2	1165841.SULAR_06818	4.26e-56	176.0	COG1539@1|root,COG1539@2|Bacteria,1RHII@1224|Proteobacteria,42V1R@68525|delta/epsilon subdivisions,2YQ8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydroneopterin aldolase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_39841_1	1121937.AUHJ01000008_gene2129	1.79e-55	184.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,4673H@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
k59_26691_1	218491.ECA1488	1.4e-09	64.3	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1MQB1@122277|Pectobacterium	1236|Gammaproteobacteria	Q	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_188910_1	207954.MED92_13261	5.15e-102	305.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XIBJ@135619|Oceanospirillales	135619|Oceanospirillales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	-	-	-	-	-	-	-	-	-	-	PALP
k59_13127_1	1410668.JNKC01000001_gene1987	0.000757	47.0	COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,36H4V@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Gram_pos_anchor
k59_87732_1	1123517.JOMR01000001_gene145	6.77e-35	131.0	2C8CV@1|root,2Z8NV@2|Bacteria,1MWPM@1224|Proteobacteria,1RQRC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3095)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3095
k59_73709_1	1395587.P364_0102495	9.68e-06	53.5	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
k59_47131_1	756272.Plabr_4750	3.09e-66	224.0	COG3119@1|root,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_209659_1	228410.NE2329	1.17e-37	142.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,3720B@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_60750_1	90675.XP_010424030.1	5.34e-09	57.8	KOG1075@1|root,KOG1075@2759|Eukaryota,37T71@33090|Viridiplantae,3GHK2@35493|Streptophyta,3I05T@3699|Brassicales	35493|Streptophyta	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	C2,DUF4283,RVT_1,RVT_3,zf-RVT
k59_53753_1	587753.EY04_21235	5e-34	135.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	pvdL	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_182469_1	1207063.P24_10066	1.49e-05	52.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2TSB6@28211|Alphaproteobacteria,2JQHC@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_60757_1	1005999.GLGR_1702	1.14e-18	81.3	2BN5D@1|root,32GSI@2|Bacteria,1RM5H@1224|Proteobacteria,1SDU7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13141_1	697282.Mettu_0993	1.05e-154	445.0	COG3385@1|root,COG3385@2|Bacteria,1NIWM@1224|Proteobacteria,1S5FT@1236|Gammaproteobacteria,1XFX0@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_39857_1	1298593.TOL_1469	1.17e-57	182.0	COG5113@1|root,COG3236@2|Bacteria,1RCXE@1224|Proteobacteria,1S8DV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	protein conserved in bacteria	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
k59_39857_2	314285.KT71_09047	1.23e-66	203.0	COG3791@1|root,COG3791@2|Bacteria,1PY7C@1224|Proteobacteria,1SXYN@1236|Gammaproteobacteria,1JBC0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_39857_3	1396858.Q666_02815	1.62e-70	215.0	COG0454@1|root,COG0456@2|Bacteria,1RGV2@1224|Proteobacteria,1S8FN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_196144_1	1168034.FH5T_08385	6.76e-49	175.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_141811_1	1121930.AQXG01000007_gene478	1.38e-09	59.3	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1IR43@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_141811_2	518766.Rmar_1421	3.16e-124	368.0	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_121735_1	177439.DP0421	4.05e-13	74.7	COG0358@1|root,COG0358@2|Bacteria,1P00T@1224|Proteobacteria	1224|Proteobacteria	L	Toprim-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF927,Toprim_2
k59_40436_1	935863.AWZR01000001_gene1928	4.11e-106	318.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1X43Q@135614|Xanthomonadales	135614|Xanthomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_114783_1	118163.Ple7327_0933	3.48e-23	97.8	2DBVQ@1|root,2ZBCX@2|Bacteria,1GQCQ@1117|Cyanobacteria,3VNIJ@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_16475_2	1349785.BAUG01000004_gene356	1e-48	164.0	COG3637@1|root,COG3637@2|Bacteria,4NX35@976|Bacteroidetes,1I9V6@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_43445_1	1249627.D779_1895	9.71e-68	214.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1WX0R@135613|Chromatiales	135613|Chromatiales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_178916_1	1353529.M899_2051	1.88e-61	202.0	KOG0788@1|root,2Z9Q6@2|Bacteria,1R6QG@1224|Proteobacteria	1224|Proteobacteria	E	PFAM S-adenosylmethionine decarboxylase	speD	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	SAM_decarbox
k59_50522_1	1121104.AQXH01000001_gene1400	1.41e-45	163.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_118402_1	395493.BegalDRAFT_2362	7.81e-11	67.4	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,461AE@72273|Thiotrichales	72273|Thiotrichales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
k59_192748_1	983544.Lacal_1829	3.34e-19	85.9	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_192748_2	1168034.FH5T_17185	9.74e-35	128.0	COG2071@1|root,COG2071@2|Bacteria	2|Bacteria	S	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	puuD	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
k59_98065_1	395493.BegalDRAFT_0240	2.82e-69	216.0	COG2201@1|root,COG2201@2|Bacteria,1RCWE@1224|Proteobacteria,1S6II@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	protein-glutamate methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
k59_50523_1	1313172.YM304_33630	3.92e-41	157.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
k59_145339_1	1144275.COCOR_02059	3.56e-35	137.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_77523_2	1178482.BJB45_03615	2.53e-31	120.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,1XHUZ@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_138330_1	1120963.KB894491_gene1137	9.48e-09	62.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,2Q1NH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_138330_2	670292.JH26_25990	7.13e-05	47.8	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,1JRTD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_185861_1	2340.JV46_11150	1.87e-134	393.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1J80F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_213030_1	1165841.SULAR_07355	8.32e-46	160.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_213030_2	765912.Thimo_1331	6.1e-55	177.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1WY8B@135613|Chromatiales	135613|Chromatiales	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_158853_1	555778.Hneap_2110	5.33e-68	213.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1WWPE@135613|Chromatiales	135613|Chromatiales	G	HAD-superfamily hydrolase, subfamily IA, variant 3	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_36614_1	1165841.SULAR_09569	2.5e-112	332.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_30256_1	595460.RRSWK_00866	6.63e-57	192.0	COG0517@1|root,COG0517@2|Bacteria,2J27U@203682|Planctomycetes	203682|Planctomycetes	S	Best DB hits BLAST	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_213035_1	933262.AXAM01000006_gene1869	4.72e-90	273.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2MIBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k59_131732_1	1121459.AQXE01000001_gene2816	2.02e-70	228.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2M8KS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_158857_1	317025.Tcr_1242	2.74e-71	222.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,46091@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_30261_1	1408473.JHXO01000006_gene1315	5.15e-74	228.0	COG0500@1|root,COG2226@2|Bacteria,4PHN8@976|Bacteroidetes,2FVJG@200643|Bacteroidia	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36624_1	387093.SUN_1006	1.09e-107	317.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,42QE2@68525|delta/epsilon subdivisions,2YNKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_57118_1	768671.ThimaDRAFT_2692	2.28e-12	64.7	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,1S54N@1236|Gammaproteobacteria,1WVV7@135613|Chromatiales	135613|Chromatiales	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_57118_2	998674.ATTE01000001_gene4187	3.25e-32	127.0	COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,460CF@72273|Thiotrichales	72273|Thiotrichales	V	ATP-binding protein	cydD	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
k59_84474_2	765913.ThidrDRAFT_1490	2.09e-71	222.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,1S3UT@1236|Gammaproteobacteria,1X1ZK@135613|Chromatiales	135613|Chromatiales	H	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2,UbiA
k59_111316_1	395493.BegalDRAFT_0569	1.74e-53	179.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	heptosyltransferase	rfaQ	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	iAF1260.b3632,iBWG_1329.BWG_3323,iECDH10B_1368.ECDH10B_3814,iJO1366.b3632,iSSON_1240.SSON_3775,iY75_1357.Y75_RS18975	Glyco_transf_9
k59_111316_2	300852.55773331	3.36e-29	114.0	COG3391@1|root,COG3391@2|Bacteria,1WICY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57121_1	247634.GPB2148_3814	2.79e-106	311.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1J51Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	exodeoxyribonuclease III	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_199685_1	575588.ACPN01000074_gene1509	1.22e-16	80.9	COG1573@1|root,COG1573@2|Bacteria,1QGYE@1224|Proteobacteria,1S73S@1236|Gammaproteobacteria,3NJ70@468|Moraxellaceae	1236|Gammaproteobacteria	L	Domain of unknown function (DUF4130	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
k59_199685_2	177439.DP2153	5.43e-31	111.0	2CG94@1|root,337GB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70690_2	1165841.SULAR_05853	5.59e-128	371.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2YMEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_63983_1	768066.HELO_4435	3.28e-123	372.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1XHD3@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_158866_1	313596.RB2501_14444	3.23e-38	139.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,1HYF9@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_158866_2	143224.JQMD01000002_gene746	5.11e-74	236.0	COG1012@1|root,COG1012@2|Bacteria,4NEQ2@976|Bacteroidetes,1HYQ7@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	gapN	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_192774_1	1385935.N836_04580	1.74e-21	95.1	COG0642@1|root,COG2205@2|Bacteria,1G13T@1117|Cyanobacteria,1H77Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,Response_reg
k59_192774_2	65393.PCC7424_5156	3.56e-19	86.3	COG0863@1|root,COG0863@2|Bacteria,1G1WV@1117|Cyanobacteria	1117|Cyanobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_9814_1	1122165.AUHS01000010_gene824	7.38e-64	212.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1JDR9@118969|Legionellales	118969|Legionellales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_43472_1	1165841.SULAR_07485	2.68e-119	348.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_213057_1	102129.Lepto7375DRAFT_7506	1.07e-50	182.0	COG3209@1|root,COG3209@2|Bacteria,1G3BX@1117|Cyanobacteria,1HER8@1150|Oscillatoriales	1117|Cyanobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_84485_1	1347392.CCEZ01000049_gene1324	1.64e-23	95.1	COG0778@1|root,COG0778@2|Bacteria,1V49Q@1239|Firmicutes,24IH8@186801|Clostridia,36VPW@31979|Clostridiaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_84485_2	1408433.JHXV01000036_gene240	1.97e-12	68.2	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,1HX2E@117743|Flavobacteriia,2PBPZ@246874|Cryomorphaceae	976|Bacteroidetes	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_104686_1	941449.dsx2_3261	2.33e-21	97.8	COG1463@1|root,COG1463@2|Bacteria,1Q6ZU@1224|Proteobacteria,42RZ3@68525|delta/epsilon subdivisions,2WNF0@28221|Deltaproteobacteria,2M8JA@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_91174_1	89187.ISM_10236	9.1e-27	106.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,46PZA@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
k59_70696_1	768671.ThimaDRAFT_3238	3e-40	148.0	2BUET@1|root,32PQT@2|Bacteria,1RG6G@1224|Proteobacteria,1SKB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k59_131750_1	395493.BegalDRAFT_2251	1.94e-98	305.0	COG2114@1|root,COG3447@1|root,COG2114@2|Bacteria,COG3447@2|Bacteria,1MW5Z@1224|Proteobacteria,1SZ7T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_199695_1	2340.JV46_17410	2.9e-69	223.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_199695_2	1049564.TevJSym_aq00430	1.55e-71	221.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1J6DN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	OSCP
k59_37008_1	243265.plu3469	1.06e-35	135.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1NEHF@1224|Proteobacteria,1RMJ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Peptidase_M78
k59_118892_1	1168034.FH5T_06525	1.28e-116	360.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_30654_1	1121033.AUCF01000005_gene5372	1.35e-17	86.7	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,2JQ4S@204441|Rhodospirillales	204441|Rhodospirillales	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
k59_30654_2	1049564.TevJSym_am00320	5.69e-10	59.3	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1J9H8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_64354_1	1120999.JONM01000002_gene924	1.3e-09	58.2	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,2KQZ6@206351|Neisseriales	206351|Neisseriales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_64354_2	626887.J057_20120	5.72e-74	230.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,465QZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_165960_1	345073.VC395_1995	1.31e-44	151.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XSNS@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	TLL0138	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_77891_1	1064535.MELS_1276	1.18e-24	102.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H1WE@909932|Negativicutes	909932|Negativicutes	E	threonine	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
k59_77891_2	2340.JV46_13060	1.7e-21	92.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1J5E5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_43788_1	1173264.KI913949_gene1576	1.23e-19	85.1	COG3415@1|root,COG3415@2|Bacteria,1G802@1117|Cyanobacteria	1117|Cyanobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32
k59_43788_2	768671.ThimaDRAFT_4427	3.71e-82	258.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,1S900@1236|Gammaproteobacteria,1WZQJ@135613|Chromatiales	135613|Chromatiales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_37028_1	511062.GU3_09530	1.27e-46	154.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1Y5WJ@135624|Aeromonadales	135624|Aeromonadales	S	Phosphate-starvation-inducible E	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
k59_10187_1	313596.RB2501_03405	3.87e-102	307.0	COG1914@1|root,COG1914@2|Bacteria,4NEG8@976|Bacteroidetes,1HYMN@117743|Flavobacteriia	976|Bacteroidetes	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k59_200138_1	1168034.FH5T_19530	1.03e-51	186.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_46653_1	1121939.L861_23610	4.62e-69	230.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XHFN@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_155015_1	1165841.SULAR_09604	3.87e-28	110.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_155015_2	1165841.SULAR_09609	3.59e-46	154.0	COG1387@1|root,COG1387@2|Bacteria,1MX8T@1224|Proteobacteria,43BI2@68525|delta/epsilon subdivisions,2YT8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
k59_60314_1	472759.Nhal_3711	2.9e-69	220.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales	135613|Chromatiales	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_19657_1	1123060.JONP01000007_gene5009	7.71e-09	59.7	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,2JS6N@204441|Rhodospirillales	204441|Rhodospirillales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_202504_1	2340.JV46_06590	1.53e-123	372.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1J8KX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_127908_1	2340.JV46_26520	2.29e-131	387.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1J4HM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125	GATase_6,GATase_7,Pribosyltran
k59_161877_2	595460.RRSWK_07036	3.82e-52	184.0	COG0187@1|root,COG0187@2|Bacteria,2IXF8@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_121281_1	926569.ANT_12300	2.42e-44	148.0	COG3293@1|root,COG3293@2|Bacteria,2G9EK@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
k59_161878_1	269799.Gmet_1668	2.95e-12	66.2	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria,43VIR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
k59_33156_1	1179773.BN6_68440	9.01e-54	187.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4DYDE@85010|Pseudonocardiales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_215869_1	396588.Tgr7_0842	8.82e-60	198.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1WWQM@135613|Chromatiales	135613|Chromatiales	P	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_80471_1	1415778.JQMM01000001_gene2181	4.66e-113	338.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_182067_1	2340.JV46_15930	5.71e-63	196.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1SFHK@1236|Gammaproteobacteria,1JB86@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	MraZ protein, putative antitoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	MraZ
k59_161879_1	1049564.TevJSym_ae00910	1.98e-52	177.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1J4TF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_161879_2	2340.JV46_07570	7.04e-53	171.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,1J6R4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
k59_168707_1	387093.SUN_2408	5.65e-43	166.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2YNPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_195758_1	1123257.AUFV01000003_gene1169	2.75e-62	205.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,1SM3A@1236|Gammaproteobacteria,1XDFJ@135614|Xanthomonadales	135614|Xanthomonadales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_67150_1	7668.SPU_028768-tr	6.14e-89	301.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3DE2J@33213|Bilateria	33208|Metazoa	L	Pao retrotransposon peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1758,DUF1759,Peptidase_A17,RVT_1,rve
k59_175399_1	1165841.SULAR_04607	4.97e-58	188.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,42MX3@68525|delta/epsilon subdivisions,2YR64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2951 Membrane-bound lytic murein transglycosylase B	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_175399_2	1165841.SULAR_04612	3.67e-84	265.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GGDEF,PAS_9,dCache_3
k59_33163_1	1123020.AUIE01000014_gene346	8.3e-28	115.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1YDPR@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_195761_2	1165841.SULAR_09499	7.28e-73	223.0	COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,43B1S@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_87291_1	1177179.A11A3_06958	1.91e-15	77.4	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80485_2	105559.Nwat_0443	1.65e-25	102.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_100910_1	1128421.JAGA01000002_gene116	2.58e-31	123.0	COG0436@1|root,COG0436@2|Bacteria,2NP6E@2323|unclassified Bacteria	2|Bacteria	E	PFAM Aminotransferase class I and II	ybdL	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	2.6.1.17,2.6.1.88	ko:K10907,ko:K14267,ko:K14287	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475,R08618	RC00006,RC00025	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv0858c	Aminotran_1_2
k59_87294_1	1165841.SULAR_00710	3.97e-130	406.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_141368_1	1230343.CANP01000008_gene908	2.98e-48	158.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1JE9E@118969|Legionellales	118969|Legionellales	O	bacterioferritin comigratory protein	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_107953_1	1168065.DOK_04232	2.45e-07	53.1	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1J6QU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_107953_2	1123487.KB892857_gene2436	1.04e-49	167.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,2KVAT@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_73469_1	717231.Flexsi_1467	6.89e-13	71.2	COG1102@1|root,COG1102@2|Bacteria,2GFKW@200930|Deferribacteres	200930|Deferribacteres	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_121304_1	1121935.AQXX01000114_gene3278	5.7e-33	124.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1XIEV@135619|Oceanospirillales	135619|Oceanospirillales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_134852_1	159087.Daro_1319	3.29e-69	229.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,2KVAJ@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_168732_1	2340.JV46_16270	4.3e-130	385.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1J4IR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	iYL1228.KPN_04331	ABC1
k59_148523_1	1165841.SULAR_10139	3.28e-116	344.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2YN8R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_60344_1	670487.Ocepr_0634	3.26e-74	244.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_182089_1	1049564.TevJSym_ac00130	7.15e-166	483.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide	nosZ	GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	COX2,Cupredoxin_1
k59_155048_1	313596.RB2501_09585	1.13e-54	177.0	2C59T@1|root,305DH@2|Bacteria,4NNXD@976|Bacteroidetes,1I259@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_134855_1	143224.JQMD01000002_gene2288	6.5e-77	239.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,1HX7F@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine synthase I (cobalamin-dependent), methyltransferase domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_195770_1	1121937.AUHJ01000010_gene1668	5.53e-85	254.0	COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,464BN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_46698_1	765914.ThisiDRAFT_0270	5.52e-31	122.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales	135613|Chromatiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_12671_1	314254.OA2633_11435	2.29e-07	51.6	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,43ZKA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_12671_2	1415778.JQMM01000001_gene1257	7.94e-24	94.0	2EQBS@1|root,33596@2|Bacteria,1NFEU@1224|Proteobacteria,1SFW6@1236|Gammaproteobacteria,1JB8M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3240
k59_12671_3	237368.SCABRO_00130	0.000148	45.4	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_39457_1	1165841.SULAR_01155	1.29e-09	57.8	2E36N@1|root,32Y6C@2|Bacteria,1NX8V@1224|Proteobacteria,42UV2@68525|delta/epsilon subdivisions,2YSEU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_39457_2	1165841.SULAR_01150	4.16e-115	332.0	COG2249@1|root,COG2249@2|Bacteria,1MWV9@1224|Proteobacteria,42NNM@68525|delta/epsilon subdivisions,2YNA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	modulator of drug activity	mdaB	-	-	ko:K03923	-	-	-	-	ko00000	-	-	-	Flavodoxin_2
k59_134856_1	1408473.JHXO01000008_gene2798	4.88e-66	225.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_108358_1	395493.BegalDRAFT_1285	7.57e-28	115.0	COG1672@1|root,COG1672@2|Bacteria,1N54W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_216297_1	497321.C664_06588	2.06e-57	189.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,2KX2B@206389|Rhodocyclales	206389|Rhodocyclales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_135216_1	1231190.NA8A_23744	0.000948	47.8	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2TQWR@28211|Alphaproteobacteria,43P84@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	rci	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_182476_1	886293.Sinac_6825	1.59e-08	61.2	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
k59_108365_1	4081.Solyc01g007370.2.1	9.58e-62	196.0	28IB5@1|root,2QV51@2759|Eukaryota,37SP0@33090|Viridiplantae,3GHPJ@35493|Streptophyta,44UE0@71274|asterids	35493|Streptophyta	C	CemA family	cemA	-	-	-	-	-	-	-	-	-	-	-	CemA
k59_155441_1	1296415.JACC01000039_gene4014	3.38e-77	239.0	COG1028@1|root,COG1028@2|Bacteria,4NHSE@976|Bacteroidetes,1I0J1@117743|Flavobacteriia	976|Bacteroidetes	IQ	with different specificities (Related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_39871_1	929558.SMGD1_0488	1.3e-76	236.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2YNAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_39871_2	243233.MCA1282	2.37e-44	154.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1XDK3@135618|Methylococcales	135618|Methylococcales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_169190_1	387093.SUN_1173	2.59e-77	238.0	COG1752@1|root,COG1752@2|Bacteria,1Q43H@1224|Proteobacteria,42Y72@68525|delta/epsilon subdivisions,2YR75@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_155442_1	1165841.SULAR_07575	2.77e-106	310.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,43B19@68525|delta/epsilon subdivisions,2YT52@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_216311_1	1515746.HR45_17895	4.87e-14	67.8	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,2QADG@267890|Shewanellaceae	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664	ATP-synt_B
k59_216311_2	292415.Tbd_2802	9.71e-39	130.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,1KRWR@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_216311_3	1122194.AUHU01000008_gene3364	5.25e-12	65.1	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,464QZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
k59_135226_1	395493.BegalDRAFT_1542	3.54e-148	434.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_47165_1	1165841.SULAR_02398	3.11e-20	90.1	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_47165_2	1165841.SULAR_03482	7.38e-56	181.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,42TM7@68525|delta/epsilon subdivisions,2YQ62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_114283_1	411477.PARMER_00128	2.14e-05	58.2	COG0823@1|root,COG0823@2|Bacteria,4NGH4@976|Bacteroidetes,2FN8G@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_73720_1	675635.Psed_0252	3.88e-53	194.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K16428,ko:K16429	ko01055,map01055	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_94607_1	1122604.JONR01000007_gene2852	9.53e-26	111.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1X43V@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thiol disulfide Interchange Protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_182486_1	118168.MC7420_4206	1.12e-08	61.6	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,1G2I8@1117|Cyanobacteria,1H8CU@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction protein with nacht domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,GUN4,NACHT
k59_73723_1	1165841.SULAR_01095	1.81e-21	88.2	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	CO_dh,PBP_like_2
k59_73723_2	1165841.SULAR_01100	2.38e-111	329.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_162216_1	1168034.FH5T_09495	8.99e-20	84.7	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,2FN8E@200643|Bacteroidia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_162216_2	1168034.FH5T_09490	3.93e-61	199.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,2FMQV@200643|Bacteroidia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_196165_1	1165841.SULAR_00355	4.94e-191	540.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_39888_1	1195246.AGRI_12636	1.49e-26	112.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,46428@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	COG2202 FOG PAS PAC domain	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
k59_13168_1	298654.FraEuI1c_4957	5.97e-91	280.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EUWK@85013|Frankiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldA	GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016620,GO:0016903,GO:0022607,GO:0033723,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840	-	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	-	R00711	RC00047	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_159518_1	445688.E3SNS2_9CAUD	6.03e-24	99.4	4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses  no RNA stage,4QPJE@28883|Caudovirales,4QI9Y@10662|Myoviridae	10662|Myoviridae	S	ATPase family associated with various cellular activities (AAA)	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_159518_2	238854.Q5GQL6_BPSYP	1.14e-30	120.0	4QB2Z@10239|Viruses,4QWQN@35237|dsDNA viruses  no RNA stage,4QPYN@28883|Caudovirales	28883|Caudovirales	S	gp45 sliding clamp, C terminal	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_159518_4	238854.Q5GQL7_BPSYP	1.03e-36	137.0	4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses  no RNA stage,4QPJE@28883|Caudovirales	28883|Caudovirales	S	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10346_1	1049564.TevJSym_ac00140	7.06e-78	248.0	COG1999@1|root,COG4531@1|root,COG1999@2|Bacteria,COG4531@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,1J6I1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC,ZnuA
k59_10346_2	749222.Nitsa_0495	2.02e-07	51.2	COG2010@1|root,COG4263@1|root,COG2010@2|Bacteria,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,42P9D@68525|delta/epsilon subdivisions,2YMS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	COX2,Cupredoxin_1,Cytochrom_C
k59_51023_1	387093.SUN_1391	3.41e-10	64.3	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_111928_1	2340.JV46_17620	7.79e-99	307.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1J572@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Oligopeptidase A	prlC	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_57812_1	886377.Murru_1019	3.83e-87	273.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_193469_1	338966.Ppro_1373	2.41e-32	127.0	COG5544@1|root,COG5544@2|Bacteria,1QU58@1224|Proteobacteria,42S6G@68525|delta/epsilon subdivisions,2WNWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44033_1	1165841.SULAR_10664	3.88e-56	184.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2YMD9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_23890_2	90814.KL370891_gene1376	3.9e-20	82.4	2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria,4639K@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_23890_3	717231.Flexsi_1531	9.91e-32	117.0	COG0410@1|root,COG0410@2|Bacteria	2|Bacteria	E	branched-chain amino acid transmembrane transporter activity	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_125640_1	1120999.JONM01000035_gene4198	1.16e-34	136.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KQ86@206351|Neisseriales	206351|Neisseriales	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_10352_2	1515746.HR45_18770	1.25e-71	226.0	COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,1RV4C@1236|Gammaproteobacteria,2QESZ@267890|Shewanellaceae	1236|Gammaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_71347_1	2340.JV46_08410	1.7e-52	181.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1J571@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345	SBP_bac_3,SLT
k59_111934_1	1121874.KB892377_gene873	2.18e-06	50.4	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
k59_30871_1	1165841.SULAR_04417	4.83e-136	401.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_132541_1	2340.JV46_27860	4.71e-132	389.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1JBHG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	ArsB,CitMHS
k59_91781_1	1123326.JFBL01000014_gene240	5.52e-47	179.0	COG3209@1|root,COG3209@2|Bacteria,1R0C4@1224|Proteobacteria,43CUG@68525|delta/epsilon subdivisions,2YSH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200335_1	1165841.SULAR_05973	1.37e-100	304.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2YMK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
k59_132544_1	1280390.CBQR020000058_gene1126	5.46e-08	60.8	COG3266@1|root,COG4856@1|root,COG3266@2|Bacteria,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,26RPS@186822|Paenibacillaceae	91061|Bacilli	S	Protein conserved in bacteria	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
k59_139119_1	411460.RUMTOR_01524	2.03e-16	83.6	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia,3XYWK@572511|Blautia	186801|Clostridia	S	COG COG2270 Permeases of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_166200_2	314345.SPV1_07204	7.2e-18	85.5	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria	1224|Proteobacteria	E	Gamma-glutamyltransferase	acyI	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_3789_2	1165841.SULAR_03098	7.97e-12	65.5	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_193489_1	1283300.ATXB01000001_gene2341	3.29e-74	229.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_193489_2	714943.Mucpa_4717	2.76e-31	116.0	COG3335@1|root,COG3335@2|Bacteria,4PNWI@976|Bacteroidetes,1IZ7Q@117747|Sphingobacteriia	976|Bacteroidetes	L	SPTR Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_17172_1	1249480.B649_08995	4.11e-33	124.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_152825_1	385682.AFSL01000031_gene3005	1.14e-13	74.7	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,2G2V4@200643|Bacteroidia,3XM1H@558415|Marinilabiliaceae	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_24289_1	644968.DFW101_3127	1.14e-104	321.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,42M93@68525|delta/epsilon subdivisions,2WK5I@28221|Deltaproteobacteria,2M9GS@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_159956_1	1121875.KB907551_gene1147	6.09e-54	176.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,1I26T@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	paiA	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_153196_1	29581.BW37_01171	1.5e-12	64.7	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2VQDH@28216|Betaproteobacteria,4736X@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Redoxin	ahp1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
k59_153196_2	392500.Swoo_2376	7.72e-05	48.1	COG2010@1|root,COG2010@2|Bacteria,1PDUJ@1224|Proteobacteria,1SUEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
k59_105852_1	754476.Q7A_2043	1.53e-86	270.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,4609G@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_78533_1	765420.OSCT_0473	1.62e-78	254.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G5QP@200795|Chloroflexi,3770F@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_64957_1	313628.LNTAR_11691	2.15e-39	154.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_44466_1	98439.AJLL01000090_gene135	4.33e-20	95.5	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JJEC@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_105855_1	945713.IALB_1293	5.79e-32	127.0	COG1523@1|root,COG4935@1|root,COG1523@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PUD,Reprolysin_4
k59_24301_1	1085623.GNIT_3241	2.5e-38	145.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	GGDEF domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_85534_1	33876.JNXY01000004_gene1551	9.7e-31	125.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4D8GT@85008|Micromonosporales	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,PP-binding,Thioesterase
k59_64958_1	76114.p2A163	6.03e-70	223.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,2VRJ7@28216|Betaproteobacteria,2KZUS@206389|Rhodocyclales	206389|Rhodocyclales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_33
k59_159967_1	749222.Nitsa_1979	2.89e-08	52.8	2ADBR@1|root,31316@2|Bacteria,1RD6U@1224|Proteobacteria,430GW@68525|delta/epsilon subdivisions,2YS4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2853
k59_159967_2	1165841.SULAR_10334	9.49e-42	137.0	COG2932@1|root,COG2932@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
k59_99216_3	1128427.KB904821_gene4236	2.34e-29	127.0	COG0464@1|root,COG0464@2|Bacteria,1G2M7@1117|Cyanobacteria,1HE1K@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_58261_1	1499967.BAYZ01000160_gene421	1.27e-51	183.0	COG2274@1|root,COG2274@2|Bacteria,2NS5Q@2323|unclassified Bacteria	2|Bacteria	V	Peptidase C39 family	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_31212_1	1165841.SULAR_01563	9.63e-153	439.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Z0P@68525|delta/epsilon subdivisions,2YR4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_213982_1	675817.VDA_001344	6.53e-09	56.2	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1XU58@135623|Vibrionales	135623|Vibrionales	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH
k59_213982_2	1968.JOEV01000029_gene8698	2.31e-16	89.4	COG0457@1|root,COG0457@2|Bacteria,2GJD3@201174|Actinobacteria	201174|Actinobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
k59_4198_13	1123487.KB892865_gene1388	2.89e-94	318.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	PriCT_2,Prim-Pol
k59_85543_2	981336.F944_01893	1.53e-06	49.3	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,3NK06@468|Moraxellaceae	1236|Gammaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_207514_1	446470.Snas_1894	1.41e-63	221.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EZ68@85014|Glycomycetales	201174|Actinobacteria	M	PFAM virulence plasmid 65kDa B protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
k59_33866_2	1118054.CAGW01000072_gene1701	6.82e-10	58.5	2CK5I@1|root,2ZEE3@2|Bacteria,1W4ZH@1239|Firmicutes,4HZTI@91061|Bacilli,2713S@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210063_1	1245471.PCA10_32700	4.76e-42	140.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,1S6KT@1236|Gammaproteobacteria,1YJV4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
k59_210063_2	1341181.FLJC2902T_09140	6.47e-14	66.6	COG3360@1|root,COG3360@2|Bacteria,4NURJ@976|Bacteroidetes,1I534@117743|Flavobacteriia,2NXJZ@237|Flavobacterium	976|Bacteroidetes	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_101593_1	313596.RB2501_07635	1e-115	338.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_54155_1	1121012.AUKX01000006_gene402	3.64e-87	268.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1HZAN@117743|Flavobacteriia,23FMM@178469|Arenibacter	976|Bacteroidetes	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_203301_1	1215092.PA6_009_00220	1.54e-54	194.0	291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142189_1	566466.NOR53_3441	6.48e-85	266.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1J7W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_155751_1	203119.Cthe_1371	5.78e-08	60.1	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,3WI3K@541000|Ruminococcaceae	186801|Clostridia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD,RHS_repeat
k59_20313_1	102129.Lepto7375DRAFT_0843	5.44e-17	88.6	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_74027_1	1279019.ARQK01000050_gene1298	1.53e-75	239.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_101601_2	1123277.KB893190_gene4913	6.62e-13	71.2	COG2885@1|root,COG2885@2|Bacteria,4NGCV@976|Bacteroidetes,47K14@768503|Cytophagia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_216596_1	485918.Cpin_3622	5.59e-31	127.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia	976|Bacteroidetes	M	conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
k59_54170_1	3880.AES58588	5.48e-08	52.8	2CY54@1|root,2S23H@2759|Eukaryota,3896T@33090|Viridiplantae,3GY43@35493|Streptophyta,4JWBW@91835|fabids	35493|Streptophyta	S	Ribosomal protein S10p/S20e	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_33886_1	1165841.SULAR_06328	1.09e-129	391.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_210081_1	1397278.AYMV01000028_gene2610	5.25e-26	108.0	COG2084@1|root,COG2084@2|Bacteria,2HGXH@201174|Actinobacteria,4FPIU@85023|Microbacteriaceae	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_20318_1	1165841.SULAR_01663	2.12e-73	231.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,42MVB@68525|delta/epsilon subdivisions,2YNU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	O-acetylhomoserine sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_20318_2	1165841.SULAR_01658	1.63e-16	73.9	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2YT0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_54175_2	2340.JV46_25850	6.8e-33	116.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1J6V1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsO	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698	-	ko:K08485,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1	-	-	PTS-HPr
k59_74031_1	1165841.SULAR_09934	4.12e-220	612.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_216600_1	1298867.AUES01000051_gene4511	2.44e-24	108.0	COG0771@1|root,COG2931@1|root,COG4625@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3K2H3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
k59_27030_1	313603.FB2170_07055	1.2e-25	110.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia,2PGID@252356|Maribacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_27031_1	95619.PM1_0209395	3.58e-58	193.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEcE24377_1341.EcE24377A_1004,iPC815.YPO1389,iYL1228.KPN_00935	Aminotran_5
k59_54188_1	616991.JPOO01000003_gene1065	8.7e-10	64.7	COG5661@1|root,COG5661@2|Bacteria,4PN8B@976|Bacteroidetes	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_35495_1	1123366.TH3_14684	4.11e-63	205.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2JPEG@204441|Rhodospirillales	204441|Rhodospirillales	FL	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
k59_205028_1	2340.JV46_02800	2.06e-79	246.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1J4I4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_177855_1	555779.Dthio_PD0436	3.66e-32	124.0	COG1373@1|root,COG1373@2|Bacteria,1MWDX@1224|Proteobacteria,42Q61@68525|delta/epsilon subdivisions,2WM4W@28221|Deltaproteobacteria,2MG0J@213115|Desulfovibrionales	555779.Dthio_PD0436|-	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123741_1	765911.Thivi_4140	2.74e-99	301.0	COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,1S58V@1236|Gammaproteobacteria,1X0Q7@135613|Chromatiales	135613|Chromatiales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_150830_1	396588.Tgr7_1159	1.7e-95	285.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1WW47@135613|Chromatiales	135613|Chromatiales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_177857_1	1165841.SULAR_03198	1.95e-43	144.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2YP5R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_177857_2	1165841.SULAR_03193	2.28e-35	130.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2YN69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_171219_1	572477.Alvin_1508	1.59e-55	175.0	COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria,1WYQ6@135613|Chromatiales	135613|Chromatiales	P	Part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_29014_1	1502852.FG94_02446	5.14e-75	236.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,472BA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
k59_76258_1	483219.LILAB_14305	1.47e-18	90.9	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,437YB@68525|delta/epsilon subdivisions,2X387@28221|Deltaproteobacteria,2YVXR@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_29017_1	247634.GPB2148_1735	2.46e-72	231.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,1RPHR@1236|Gammaproteobacteria,1J4UK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	M18 family aminopeptidase	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_143924_1	1122927.KB895416_gene3577	9.41e-25	102.0	COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,4HB9T@91061|Bacilli,272GF@186822|Paenibacillaceae	91061|Bacilli	S	Putative vitamin uptake transporter	yhhQ_2	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_191579_1	998674.ATTE01000001_gene4492	1.36e-47	153.0	COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,460SU@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
k59_69569_1	1121405.dsmv_1537	1.18e-94	291.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,2MJD6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k59_22126_1	1165841.SULAR_02103	1.7e-131	376.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42MFD@68525|delta/epsilon subdivisions,2YN54@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	NAD-dependent protein deacetylase, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	SIR2
k59_55988_1	1165841.SULAR_02043	2.67e-103	310.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2YTJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_205044_1	1249627.D779_0086	1.09e-158	461.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1WX77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_164414_1	158190.SpiGrapes_1304	0.000913	41.2	COG0040@1|root,COG0040@2|Bacteria,2J8TS@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_164414_2	340.xcc-b100_2094	5.4e-27	103.0	COG4496@1|root,COG4496@2|Bacteria,1NAAX@1224|Proteobacteria,1SG3S@1236|Gammaproteobacteria,1X7DY@135614|Xanthomonadales	135614|Xanthomonadales	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
k59_143936_1	1234364.AMSF01000013_gene673	6.59e-76	246.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales	135614|Xanthomonadales	E	Acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_62868_1	1165841.SULAR_01115	9.94e-79	241.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,42Q6E@68525|delta/epsilon subdivisions,2YQCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
k59_96711_1	204669.Acid345_0985	7.72e-45	155.0	COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria,2JKGK@204432|Acidobacteriia	204432|Acidobacteriia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_62870_1	1165841.SULAR_09979	3.03e-64	208.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,430CZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_62870_2	387093.SUN_0196	2.39e-77	246.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,43BKT@68525|delta/epsilon subdivisions,2YN1M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k59_177880_1	387093.SUN_2329	5.14e-29	104.0	COG0255@1|root,COG0255@2|Bacteria,1Q5ZI@1224|Proteobacteria,42VCR@68525|delta/epsilon subdivisions,2YQ6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_177880_2	1165841.SULAR_07995	1.39e-90	266.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2YNWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_177880_3	1165841.SULAR_08000	3.37e-57	182.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2YN05@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_42405_1	1265505.ATUG01000002_gene2628	4.18e-127	377.0	COG0730@1|root,COG0730@2|Bacteria,1N1I6@1224|Proteobacteria,42N92@68525|delta/epsilon subdivisions,2WJT2@28221|Deltaproteobacteria,2MIX7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_211973_1	870187.Thini_2168	1.81e-153	442.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Iron-sulfur cluster binding protein	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_8408_1	1165841.SULAR_05198	1.17e-15	74.7	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_8408_2	1165841.SULAR_05228	8.39e-89	267.0	COG1672@1|root,COG1672@2|Bacteria,1PMVJ@1224|Proteobacteria,42PCP@68525|delta/epsilon subdivisions,2YNZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Archaea bacterial proteins of	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_62872_1	1274374.CBLK010000070_gene1112	2.96e-69	225.0	COG0668@1|root,COG0668@2|Bacteria,1TSHU@1239|Firmicutes,4HBC1@91061|Bacilli,26T2D@186822|Paenibacillaceae	91061|Bacilli	M	Mechanosensitive ion channel	-	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
k59_29049_1	1165841.SULAR_01065	4.25e-49	158.0	2BTTK@1|root,32P16@2|Bacteria,1Q41F@1224|Proteobacteria,42Y3I@68525|delta/epsilon subdivisions,2YQQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_143949_2	395493.BegalDRAFT_2566	4.83e-28	106.0	COG0500@1|root,COG2226@2|Bacteria,1RFGA@1224|Proteobacteria,1S4V2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_157790_1	1238182.C882_4529	1.62e-101	310.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2TRUJ@28211|Alphaproteobacteria,2JQ8I@204441|Rhodospirillales	204441|Rhodospirillales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_15368_1	1165841.SULAR_02048	3.71e-123	362.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2YRI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_164429_1	247490.KSU1_C1314	2.05e-53	186.0	COG0535@1|root,COG0535@2|Bacteria,2J2KS@203682|Planctomycetes	203682|Planctomycetes	S	Proto-chlorophyllide reductase 57 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	PCP_red,Radical_SAM,SPASM
k59_35545_1	391008.Smal_3298	1.18e-09	62.8	COG0515@1|root,COG0515@2|Bacteria,1QVSB@1224|Proteobacteria,1SJ90@1236|Gammaproteobacteria,1XCXV@135614|Xanthomonadales	135614|Xanthomonadales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184784_1	626418.bglu_2g12850	9.45e-40	147.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2VHAK@28216|Betaproteobacteria,1K410@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_171267_1	506534.Rhein_3384	3.26e-77	246.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WYHW@135613|Chromatiales	135613|Chromatiales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_171270_1	1150399.AQYK01000001_gene1162	2.34e-11	66.2	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4FKXH@85023|Microbacteriaceae	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	pkn1	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0055114,GO:0071704,GO:0120147,GO:1901564	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_22139_1	1123401.JHYQ01000003_gene2171	2.4e-92	282.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,45ZMN@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_49346_1	1266909.AUAG01000063_gene1806	1.33e-126	373.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1WZPM@135613|Chromatiales	135613|Chromatiales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_110276_1	1000565.METUNv1_03496	4.14e-15	74.7	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,2KW06@206389|Rhodocyclales	206389|Rhodocyclales	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_110276_2	395495.Lcho_0067	6.84e-48	169.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KNAW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_62886_1	1415778.JQMM01000001_gene1258	8.73e-62	213.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1J4SU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_164437_1	296591.Bpro_4822	1.99e-11	69.3	COG4191@1|root,COG4191@2|Bacteria,1R3RN@1224|Proteobacteria,2VPMH@28216|Betaproteobacteria,4AGQ3@80864|Comamonadaceae	28216|Betaproteobacteria	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_8424_2	1278307.KB906970_gene1098	5.68e-16	73.9	COG3153@1|root,COG3153@2|Bacteria,1RHPP@1224|Proteobacteria,1S7G1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	acetyltransferase	VVA1529	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Acetyltransf_9
k59_117186_1	713586.KB900536_gene91	1.53e-67	223.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
k59_103470_1	313596.RB2501_07015	4.77e-29	115.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IJ85@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3
k59_103470_2	313596.RB2501_07020	3.66e-45	154.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_35556_1	1541065.JRFE01000011_gene4574	8.99e-46	162.0	COG3385@1|root,COG3385@2|Bacteria,1G2NV@1117|Cyanobacteria,3VMET@52604|Pleurocapsales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1,DDE_Tnp_2
k59_35556_2	879212.DespoDRAFT_02660	3.84e-56	189.0	COG3385@1|root,COG3385@2|Bacteria,1NNH0@1224|Proteobacteria	1224|Proteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83344_1	2340.JV46_09750	2.79e-87	273.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1J4UV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_90031_1	387093.SUN_0193	3.03e-193	556.0	COG4166@1|root,COG4166@2|Bacteria,1Q4KZ@1224|Proteobacteria,43A0X@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_130486_1	1165841.SULAR_00400	2.76e-59	194.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2YMMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_130486_2	1165841.SULAR_00395	6.93e-97	289.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2YMCC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_171285_1	1125863.JAFN01000001_gene1027	4.38e-76	238.0	COG1250@1|root,COG1250@2|Bacteria,1RKDY@1224|Proteobacteria,42YWC@68525|delta/epsilon subdivisions,2WURQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH_N
k59_22150_1	95619.PM1_0224395	8.34e-53	183.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fad linked oxidase	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_130490_1	396588.Tgr7_3218	1.23e-19	84.7	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans	fkpB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_130490_2	754477.Q7C_467	2.54e-28	107.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,460TI@72273|Thiotrichales	72273|Thiotrichales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_103478_2	43228.XP_007730381.1	2.86e-10	62.0	COG1225@1|root,2SIVC@2759|Eukaryota,39QSZ@33154|Opisthokonta,3Q6TZ@4751|Fungi,3RPMI@4890|Ascomycota	4751|Fungi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_35570_1	2340.JV46_16830	2.71e-85	256.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1J5T9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions	slmA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
k59_137313_1	2340.JV46_15110	9.96e-64	207.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1J4S0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
k59_96767_1	907239.HPSA_02765	8.63e-40	146.0	COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,42U0V@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k59_191623_1	742817.HMPREF9449_01400	7.82e-33	124.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,2FNHU@200643|Bacteroidia,22XBJ@171551|Porphyromonadaceae	976|Bacteroidetes	E	LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_5910_3	398512.JQKC01000052_gene2672	2.59e-101	307.0	2C8MZ@1|root,2ZA7T@2|Bacteria,1UFFD@1239|Firmicutes,24F4E@186801|Clostridia,3WN3M@541000|Ruminococcaceae	186801|Clostridia	S	Family of unknown function (DUF5309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5309
k59_80104_1	1348114.OM33_16190	3.96e-61	214.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q42B@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_46283_1	118173.KB235914_gene3855	3.51e-26	115.0	COG2133@1|root,COG2931@1|root,COG5434@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG5434@2|Bacteria,1G0JG@1117|Cyanobacteria,1HADF@1150|Oscillatoriales	1117|Cyanobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349,DUF4347,Pectate_lyase_3
k59_73237_1	765914.ThisiDRAFT_1141	4.26e-51	175.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_73237_2	395493.BegalDRAFT_1132	5.85e-33	117.0	2BQ8D@1|root,32J37@2|Bacteria,1PCFP@1224|Proteobacteria,1SXG7@1236|Gammaproteobacteria,463B8@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73237_3	765914.ThisiDRAFT_0335	3.5e-38	140.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1WWRB@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k59_161598_1	1121935.AQXX01000126_gene952	3.64e-12	71.2	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,1T1G3@1236|Gammaproteobacteria,1XRS7@135619|Oceanospirillales	135619|Oceanospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
k59_100530_1	1165841.SULAR_01210	2.51e-137	405.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42PNH@68525|delta/epsilon subdivisions,2YRFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_66777_1	1168034.FH5T_18935	6.3e-123	369.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,2FQB7@200643|Bacteroidia	976|Bacteroidetes	C	dehydrogenase E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_32787_1	745411.B3C1_08781	4.86e-48	174.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,DUF285,FIVAR,PG_binding_1,Pertactin,Phage_fiber_2,Sel1,YSIRK_signal
k59_202181_1	313603.FB2170_00410	1.26e-75	229.0	COG5502@1|root,COG5502@2|Bacteria,4NN8N@976|Bacteroidetes,1I1CJ@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
k59_120964_1	1125863.JAFN01000001_gene2110	4.74e-08	53.9	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_120964_2	1137271.AZUM01000005_gene99	1.65e-05	49.7	COG1051@1|root,COG2062@1|root,COG1051@2|Bacteria,COG2062@2|Bacteria,2I2N2@201174|Actinobacteria,4DZW1@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
k59_188430_1	472759.Nhal_3890	1.05e-28	110.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales	135613|Chromatiales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
k59_188430_2	1144325.PMI22_05637	8.96e-05	44.3	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_161605_1	631362.Thi970DRAFT_03553	2.11e-41	155.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_93847_1	1265503.KB905167_gene1768	3.34e-10	62.8	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,2Q6WG@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Multi-copper polyphenol oxidoreductase laccase	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_107606_2	1165841.SULAR_06003	2.9e-58	182.0	COG2863@1|root,COG2863@2|Bacteria,1PFA2@1224|Proteobacteria,42XJ8@68525|delta/epsilon subdivisions,2YQVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome c class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_120966_1	1117958.PE143B_0126170	5.05e-17	81.3	COG1120@1|root,COG1120@2|Bacteria,1MWPV@1224|Proteobacteria,1RZ91@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HP	abc transporter atp-binding protein	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_120966_2	1246448.ANAZ01000010_gene3257	5.95e-28	111.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4EG7Y@85012|Streptosporangiales	201174|Actinobacteria	P	FecCD transport family	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_195480_1	1123393.KB891326_gene13	3.64e-55	177.0	COG1416@1|root,COG1416@2|Bacteria,1NAV2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_195480_2	713586.KB900536_gene2810	2.71e-24	100.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_202190_1	990073.ATHU01000001_gene199	7.05e-61	203.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_174984_1	1336233.JAEH01000013_gene3464	7.33e-47	171.0	COG0457@1|root,COG0457@2|Bacteria,1PBYW@1224|Proteobacteria,1SWS0@1236|Gammaproteobacteria,2QDGR@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_86967_1	755178.Cyan10605_1717	8.13e-28	122.0	COG2274@1|root,COG2274@2|Bacteria,1G1Y7@1117|Cyanobacteria	1117|Cyanobacteria	V	TIGRFAM NHLM bacteriocin system ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_19349_2	981085.XP_010095761.1	2.6e-30	121.0	COG2801@1|root,KOG1839@1|root,KOG0017@2759|Eukaryota,KOG1839@2759|Eukaryota,37HWS@33090|Viridiplantae,3G83W@35493|Streptophyta,4JF31@91835|fabids	35493|Streptophyta	L	Clustered mitochondria protein	-	-	-	ko:K03255	-	-	-	-	ko00000,ko03012	-	-	-	CLU_N,TPR_12,eIF3_p135
k59_46303_2	344747.PM8797T_26050	4.52e-06	50.1	COG1520@1|root,COG1520@2|Bacteria,2IX6B@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_202195_1	439235.Dalk_0941	8.77e-44	156.0	COG2984@1|root,COG2984@2|Bacteria,1R84M@1224|Proteobacteria,42PKD@68525|delta/epsilon subdivisions,2WMBV@28221|Deltaproteobacteria,2MJYP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
k59_202195_2	1408164.MOLA814_00485	2.64e-05	45.8	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_107618_1	349521.HCH_06406	1.17e-51	183.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1XHHF@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
k59_202198_1	768671.ThimaDRAFT_4062	1.32e-18	87.0	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1WY3A@135613|Chromatiales	135613|Chromatiales	T	SH3 domain	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k59_39104_1	95619.PM1_0213770	7.18e-50	166.0	COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,1RQ7J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_161629_1	7234.FBpp0180806	6.16e-09	63.5	KOG4155@1|root,KOG4155@2759|Eukaryota,39TPU@33154|Opisthokonta,3BC39@33208|Metazoa,3D1JB@33213|Bilateria,41Y1R@6656|Arthropoda,3SIR0@50557|Insecta,44Y7E@7147|Diptera,45XCM@7214|Drosophilidae	33208|Metazoa	S	WD domain, G-beta repeat	-	GO:0003008,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0007600,GO:0007606,GO:0008150,GO:0010033,GO:0010243,GO:0030424,GO:0030425,GO:0032501,GO:0036477,GO:0042221,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043279,GO:0044297,GO:0044424,GO:0044463,GO:0044464,GO:0050877,GO:0050896,GO:0050909,GO:0050913,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1901698	-	ko:K11887	-	-	-	-	ko00000,ko03051	-	-	-	WD40
k59_32817_1	545264.KB898744_gene1891	2.29e-12	66.6	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_32817_2	1499967.BAYZ01000104_gene3654	7.03e-63	204.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
k59_154685_1	1165841.SULAR_00715	3.84e-36	128.0	COG0483@1|root,COG0483@2|Bacteria,1Q17W@1224|Proteobacteria,42T1U@68525|delta/epsilon subdivisions,2YPGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_154685_2	1165841.SULAR_00710	1.48e-108	346.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_148167_1	1121896.JMLU01000019_gene790	7.77e-05	53.9	COG0358@1|root,COG5545@1|root,COG0358@2|Bacteria,COG5545@2|Bacteria,4NETK@976|Bacteroidetes,1HXGM@117743|Flavobacteriia,2NS97@237|Flavobacterium	976|Bacteroidetes	L	Protein of unknown function (DUF3987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987,VirE_N
k59_25852_1	1165841.SULAR_08567	7.33e-22	92.4	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2YMPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0324 family	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_25852_2	387093.SUN_0014	3.87e-60	200.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_181690_1	1165841.SULAR_08729	1.5e-109	317.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2YTQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_181690_2	1165841.SULAR_08734	4.07e-17	75.9	COG2236@1|root,COG2236@2|Bacteria,1Q1HY@1224|Proteobacteria,42TR4@68525|delta/epsilon subdivisions,2YP9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	phosphoribosyltransferase	gpt	-	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_32824_2	435908.IDSA_10965	1.08e-50	166.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,2QFCE@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_161636_2	1121861.KB899916_gene1707	5.74e-89	274.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2TT31@28211|Alphaproteobacteria,2JPK9@204441|Rhodospirillales	204441|Rhodospirillales	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_154691_1	387093.SUN_1901	6.53e-11	62.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_154691_2	1165841.SULAR_06308	1.85e-93	273.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42T1B@68525|delta/epsilon subdivisions,2YPHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_154691_3	1165841.SULAR_06313	2.44e-28	113.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07676,ko:K10715,ko:K20976	ko02020,ko02024,ko02025,ko02026,map02020,map02024,map02025,map02026	M00474,M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg
k59_202213_1	1168034.FH5T_05850	1.62e-97	306.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,2FN8Q@200643|Bacteroidia	976|Bacteroidetes	U	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_107639_1	313596.RB2501_01735	3.56e-83	271.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_148180_1	886377.Murru_1437	7.63e-107	315.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_195509_1	933262.AXAM01000010_gene1407	2.62e-84	261.0	COG1662@1|root,COG1662@2|Bacteria,1Q56I@1224|Proteobacteria,430ND@68525|delta/epsilon subdivisions,2WVQF@28221|Deltaproteobacteria,2MNPZ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IS1 transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_113574_1	1254432.SCE1572_24725	1.46e-46	172.0	COG1020@1|root,COG3319@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,43BZC@68525|delta/epsilon subdivisions,2X7A3@28221|Deltaproteobacteria,2YWPR@29|Myxococcales	28221|Deltaproteobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt
k59_100560_2	314278.NB231_04395	5.67e-16	76.3	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria,1WYEW@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_154695_1	497964.CfE428DRAFT_3727	1.5e-14	74.3	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
k59_154695_2	502025.Hoch_3156	5.38e-31	118.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26528_1	1168034.FH5T_19415	1.52e-102	319.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,2FQ61@200643|Bacteroidia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
k59_19824_1	926556.Echvi_0773	4.73e-70	240.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_188736_1	1280946.HY29_03945	1.8e-42	154.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria,43Z1B@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	MA20_04810	-	3.5.1.82	ko:K01461	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_3
k59_188736_2	1121875.KB907546_gene2208	3.8e-25	102.0	COG1680@1|root,COG1680@2|Bacteria,4PI69@976|Bacteroidetes,1I0GH@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_202680_1	631362.Thi970DRAFT_03638	1.47e-40	142.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WWT5@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_41328_1	1168034.FH5T_20550	4.31e-45	159.0	COG2223@1|root,COG2223@2|Bacteria,4NHX9@976|Bacteroidetes,2FZ04@200643|Bacteroidia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_61686_1	404589.Anae109_4094	4.97e-63	216.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_210843_1	1165841.SULAR_02118	3.44e-95	296.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,42MZ4@68525|delta/epsilon subdivisions,2YNF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_14266_1	857087.Metme_4122	2.48e-61	192.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XF6D@135618|Methylococcales	135618|Methylococcales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_14266_2	882378.RBRH_00800	2.24e-15	70.1	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VX5F@28216|Betaproteobacteria,1KHAT@119060|Burkholderiaceae	28216|Betaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
k59_156613_1	679937.Bcop_1121	5.97e-33	130.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_7373_1	1165841.SULAR_03442	2.45e-18	77.0	2AK15@1|root,31AQQ@2|Bacteria,1Q5Z2@1224|Proteobacteria,43242@68525|delta/epsilon subdivisions,2YSUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27817_1	90814.KL370891_gene740	3.06e-90	291.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,45ZVJ@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_183630_1	1487953.JMKF01000035_gene1217	1.2e-43	162.0	COG4191@1|root,COG4191@2|Bacteria,1G0DI@1117|Cyanobacteria,1H7WA@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
k59_102386_1	96561.Dole_2548	8.22e-78	238.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2MI6N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qrcC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
k59_102386_2	1121405.dsmv_1078	4.1e-30	119.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,2MI3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_48108_1	143224.JQMD01000002_gene2774	1.01e-15	76.3	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_48108_2	616991.JPOO01000001_gene2967	2.06e-84	266.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia,23FR4@178469|Arenibacter	976|Bacteroidetes	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_122664_1	1123070.KB899252_gene982	3.83e-54	185.0	COG4313@1|root,COG4313@2|Bacteria,46YUS@74201|Verrucomicrobia,2IVMT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_176884_1	1165841.SULAR_01648	6.53e-93	277.0	2AINN@1|root,31954@2|Bacteria,1NDHA@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_82041_1	713586.KB900536_gene1619	2.27e-70	228.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1WXYV@135613|Chromatiales	135613|Chromatiales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_170088_1	102107.XP_008224000.1	1.83e-307	912.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta,4JREA@91835|fabids	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	ycf1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	-	-	-	-	-	-	-	-	-	Ycf1
k59_75206_1	865937.Gilli_1500	5.26e-10	64.7	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,1HZ0N@117743|Flavobacteriia,2P5R6@244698|Gillisia	976|Bacteroidetes	KT	COGs COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_115936_1	768671.ThimaDRAFT_1939	1.39e-124	368.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,1T5B6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_109110_1	1165841.SULAR_07895	6.16e-124	359.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2YM93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_109110_2	1165841.SULAR_07900	3.62e-92	272.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2YMCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_183643_1	1165841.SULAR_01005	2.17e-63	206.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2YMFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_27835_1	395493.BegalDRAFT_3259	6.26e-79	241.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,45ZU2@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_142987_1	267608.RSc1700	1.63e-41	142.0	COG4678@1|root,COG4678@2|Bacteria,1R92U@1224|Proteobacteria,2VUZ6@28216|Betaproteobacteria,1K9F9@119060|Burkholderiaceae	28216|Betaproteobacteria	G	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	Phage_lysozyme
k59_54933_1	1317122.ATO12_04935	4.39e-54	192.0	COG1028@1|root,COG3321@1|root,COG4221@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia,2YGKF@290174|Aquimarina	976|Bacteroidetes	IQ	PKS_DH	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_75219_1	1165841.SULAR_05268	2.17e-140	403.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2YM8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_68496_1	1165841.SULAR_04177	1.08e-42	148.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_68496_2	1165841.SULAR_04182	1.8e-85	254.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,42V9F@68525|delta/epsilon subdivisions,2YQRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_68496_3	1165841.SULAR_04187	7.63e-47	154.0	COG4807@1|root,COG4807@2|Bacteria,1N991@1224|Proteobacteria,43BD5@68525|delta/epsilon subdivisions,2YQNH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1456)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
k59_694_1	1121441.AUCX01000021_gene730	3.13e-81	246.0	COG1177@1|root,COG1177@2|Bacteria,1MV84@1224|Proteobacteria	1224|Proteobacteria	P	ABC-type spermidine putrescine transport system, permease component II	MA20_32205	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_109120_1	395493.BegalDRAFT_2461	1.24e-73	240.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4623I@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CcmF_C,Cytochrom_C_asm
k59_34630_1	1485545.JQLW01000009_gene47	4.89e-60	196.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria	1224|Proteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSbBS512_1146.SbBS512_E3351	PGK
k59_34630_2	2340.JV46_03540	2.75e-31	117.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4IE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
k59_102414_1	296587.XP_002501992.1	1.65e-38	147.0	COG1026@1|root,KOG2019@2759|Eukaryota,37R6J@33090|Viridiplantae,34GSW@3041|Chlorophyta	3041|Chlorophyta	O	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_88856_1	247639.MGP2080_11128	1.48e-79	243.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exodeoxyribonuclease III	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_163397_1	1165841.SULAR_08607	2.23e-44	148.0	2AW1P@1|root,31MW9@2|Bacteria,1QJNC@1224|Proteobacteria,42Y3R@68525|delta/epsilon subdivisions,2YQZ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_163397_2	1165841.SULAR_08612	4.07e-42	140.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2YPMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_170112_1	1168034.FH5T_02500	1.89e-58	194.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_27845_1	887327.HMPREF0476_0349	1.7e-34	131.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,2KPIX@206351|Neisseriales	206351|Neisseriales	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_704_1	679191.HMPREF9018_0033	0.000443	44.3	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia	976|Bacteroidetes	H	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF4301
k59_68517_1	1029823.AFIE01000001_gene2103	4.15e-106	320.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,3NJ0S@468|Moraxellaceae	1236|Gammaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_102422_1	313603.FB2170_07984	1.22e-114	360.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1HXEG@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_14294_1	1009370.ALO_14397	1.02e-24	107.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H2S2@909932|Negativicutes	909932|Negativicutes	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_34640_2	572477.Alvin_0956	2.45e-27	104.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1WYG6@135613|Chromatiales	135613|Chromatiales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_210873_1	1423144.Gal_02387	1.46e-21	93.2	COG2197@1|root,COG2197@2|Bacteria,1RDUR@1224|Proteobacteria,2U7E1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	COG2771 DNA-binding HTH domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_149813_1	313596.RB2501_06545	1.03e-09	58.2	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_149813_2	867900.Celly_1393	2.01e-61	197.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia,1F914@104264|Cellulophaga	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_95579_1	59689.fgenesh2_kg.2__723__ATCG00270.1	2.52e-264	723.0	2CNIT@1|root,2QWJF@2759|Eukaryota,37RZQ@33090|Viridiplantae,3GF68@35493|Streptophyta	35493|Streptophyta	C	Photosystem II (PSII) is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1 D2 (PsbA PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex	psbD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0010287,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	1.10.3.9	ko:K02706	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Photo_RC
k59_95579_2	4572.TRIUR3_00075-P1	8.6e-301	822.0	28ISP@1|root,2QR3X@2759|Eukaryota,37T53@33090|Viridiplantae,3G7SE@35493|Streptophyta,3KP6W@4447|Liliopsida,3IG0F@38820|Poales	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbC	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k59_163403_1	1165841.SULAR_06423	1.66e-58	189.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2YMK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_75246_1	1461577.CCMH01000006_gene2118	4.14e-55	186.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_48151_1	991905.SL003B_3944	1.41e-49	171.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2TTSG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	beta-lactamase	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_129447_1	3880.AES66713	6.92e-34	119.0	2E8XP@1|root,2SFC6@2759|Eukaryota,37XVB@33090|Viridiplantae,3GMRR@35493|Streptophyta,4JV96@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115970_1	1168034.FH5T_16965	1.04e-76	237.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149816_1	349521.HCH_04317	1.46e-07	57.0	COG4935@1|root,COG4935@2|Bacteria,1NJV7@1224|Proteobacteria,1RN7Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_4
k59_176922_1	411464.DESPIG_00449	1.72e-29	118.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria,2M7UE@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_170810_1	1168034.FH5T_06525	4.91e-91	291.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_82784_1	1232683.ADIMK_1232	6.72e-48	168.0	COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,1T42H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C13
k59_89595_2	458817.Shal_2432	1.3e-24	99.8	COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,1T24M@1236|Gammaproteobacteria,2QEVY@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
k59_62411_1	1121935.AQXX01000095_gene2582	3.42e-84	265.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria	1224|Proteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483,ko:K11183	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
k59_75780_1	1165841.SULAR_01758	3.28e-214	608.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_136857_1	1461577.CCMH01000011_gene1772	1.35e-89	281.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1I0PW@117743|Flavobacteriia	976|Bacteroidetes	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1380_1	570268.ANBB01000033_gene2039	1.26e-25	101.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4EIFX@85012|Streptosporangiales	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
k59_41938_1	377629.TERTU_3372	1.87e-12	72.8	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,2PQ0B@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_69065_2	760117.JN27_01145	5.2e-41	143.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2VVF7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
k59_96299_1	1392498.JQLH01000001_gene2545	8.24e-45	157.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1HZ1W@117743|Flavobacteriia,2PHTE@252356|Maribacter	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_143572_1	1123355.JHYO01000016_gene1867	5.25e-35	131.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,36XYC@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Carboxyl transferase domain	mccB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_143572_2	1123355.JHYO01000016_gene1866	1.08e-71	227.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_8030_1	247634.GPB2148_1374	2.15e-105	324.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1J5GZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	GM	Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_123311_1	1168034.FH5T_15240	1.49e-65	219.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,2FX71@200643|Bacteroidia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_55618_1	868595.Desca_1607	7.91e-08	55.5	COG0784@1|root,COG2199@1|root,COG5000@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,COG5000@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,265M5@186807|Peptococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,FIST,FIST_C,GGDEF,PAS,PAS_8,PAS_9,Response_reg
k59_96304_1	1216007.AOPM01000021_gene3073	1.64e-67	224.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2PZZY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_82807_1	1200792.AKYF01000010_gene2781	2.13e-31	127.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K16093	ko01054,map01054	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_109823_1	1123296.JQKE01000063_gene1644	1.75e-08	55.5	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,2KPYU@206351|Neisseriales	206351|Neisseriales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_109823_2	1122207.MUS1_13660	1.8e-46	159.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1XI8M@135619|Oceanospirillales	135619|Oceanospirillales	M	Arabinose 5-phosphate isomerase	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_55620_2	326297.Sama_3114	3.98e-14	74.3	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,1S6US@1236|Gammaproteobacteria,2QBT5@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130065_1	1195073.I6WLQ1_9CAUD	1.82e-25	101.0	4QG5T@10239|Viruses,4QYVN@35237|dsDNA viruses  no RNA stage,4QTYJ@28883|Caudovirales,4QNPX@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130065_3	1219031.BBJR01000065_gene1151	4.01e-16	75.9	2CIBZ@1|root,2ZH0V@2|Bacteria,1PBAQ@1224|Proteobacteria,2W5YZ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_96315_1	1453498.LG45_04030	1.84e-23	98.6	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia,2NV9Y@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_62436_1	395493.BegalDRAFT_1057	7.74e-75	226.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	CP_0464	-	-	ko:K01999,ko:K07001	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	HTH_Crp_2,cNMP_binding
k59_103077_1	1165841.SULAR_04622	2.9e-38	135.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_103077_2	387093.SUN_1561	5.56e-61	189.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k59_1398_1	4081.Solyc01g007340.2.1	3.33e-263	732.0	COG4799@1|root,KOG0540@2759|Eukaryota,37NPW@33090|Viridiplantae,3GG0Z@35493|Streptophyta,44QTN@71274|asterids	35493|Streptophyta	H	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963,ko:K02696	ko00061,ko00195,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00195,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Carboxyl_trans,PSI_8
k59_163963_2	1159870.KB907784_gene2192	1.08e-20	94.4	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2VKSJ@28216|Betaproteobacteria,3T9IC@506|Alcaligenaceae	28216|Betaproteobacteria	S	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_1399_2	387093.SUN_0517	2.77e-62	203.0	COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,43DZE@68525|delta/epsilon subdivisions,2YRGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
k59_177487_1	1165841.SULAR_05343	1.3e-43	147.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2YT0S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_69097_1	754476.Q7A_2567	2.54e-28	115.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,45ZYF@72273|Thiotrichales	72273|Thiotrichales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_82826_1	1121374.KB891576_gene673	6.02e-05	45.1	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RPVB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	3-hydroxyacyl-coa dehydrogenase	paaH	GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_1532,iJN746.PP_3282	3HCDH,3HCDH_N
k59_82826_2	1123279.ATUS01000001_gene1815	2.05e-87	266.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,1RPE2@1236|Gammaproteobacteria,1J4CT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase carnithine racemase	paaG	GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_1531,iJN746.PP_3283,iYL1228.KPN_01475	ECH_1
k59_69098_1	1122179.KB890469_gene599	1.48e-38	147.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_170842_1	1121920.AUAU01000023_gene2415	2.53e-24	101.0	COG0664@1|root,COG1716@1|root,COG0664@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,cNMP_binding
k59_184297_1	1121878.AUGL01000010_gene1038	7.08e-70	222.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSbBS512_1146.SbBS512_E3351	PGK
k59_184297_2	105559.Nwat_0283	1.98e-30	119.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales	135613|Chromatiales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_163969_1	1122226.AUHX01000006_gene2205	0.000379	44.3	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_136888_1	1165841.SULAR_01678	6.2e-79	246.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_136888_2	1165841.SULAR_01673	1.89e-136	391.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2YMK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_116776_1	1168034.FH5T_16995	4.52e-93	275.0	COG0526@1|root,COG0526@2|Bacteria,4NNMK@976|Bacteroidetes,2FQ45@200643|Bacteroidia	976|Bacteroidetes	CO	Redoxin family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_116776_2	1168034.FH5T_17000	1.5e-74	230.0	COG0788@1|root,COG0788@2|Bacteria,4NEGJ@976|Bacteroidetes,2FN3H@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_41967_1	1165841.SULAR_01035	2.14e-101	317.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	2|Bacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_143589_2	1168034.FH5T_18900	2.48e-48	164.0	COG2197@1|root,COG2197@2|Bacteria,4NP7F@976|Bacteroidetes	976|Bacteroidetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_89640_1	1165841.SULAR_10014	8.63e-93	296.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_157277_1	1396418.BATQ01000199_gene3625	1.76e-08	54.3	COG3328@1|root,COG3328@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_130084_1	1173025.GEI7407_0914	6.12e-32	125.0	COG0142@1|root,COG0142@2|Bacteria,1G0V7@1117|Cyanobacteria,1H72T@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the FPP GGPP synthase family	sds	-	2.5.1.84,2.5.1.85	ko:K05356	ko00900,ko01110,map00900,map01110	-	R07267,R09250,R09251	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_62456_2	2340.JV46_16620	5.58e-60	198.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SBMS@1236|Gammaproteobacteria,1JBHM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_1415_1	1121920.AUAU01000002_gene2061	1.96e-69	233.0	COG1530@1|root,COG1530@2|Bacteria,3Y40K@57723|Acidobacteria	57723|Acidobacteria	J	Ribonuclease, Rne Rng family	-	-	-	-	-	-	-	-	-	-	-	-	RNase_E_G,S1
k59_41968_1	2340.JV46_11970	7.93e-92	278.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1J5BW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC transporter	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_103091_1	595460.RRSWK_00179	6.43e-05	46.2	COG1520@1|root,COG1520@2|Bacteria,2IYI8@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_184303_1	225937.HP15_4072	1.02e-35	140.0	COG0697@1|root,COG2199@1|root,COG0697@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,46766@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF
k59_191251_1	331869.BAL199_15808	1.93e-11	63.5	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,4BQAJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_55650_1	293826.Amet_1439	1.79e-27	106.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12,2.7.11.1,3.6.4.13	ko:K00627,ko:K03310,ko:K03578,ko:K12132	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko01001	2.A.25	-	-	2-oxoacid_dh,Biotin_lipoyl
k59_157285_1	387093.SUN_0033	6.64e-119	361.0	COG0433@1|root,COG0433@2|Bacteria,1R7B1@1224|Proteobacteria,42NW4@68525|delta/epsilon subdivisions,2YM8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
k59_191254_1	1034807.FBFL15_0377	1.31e-59	194.0	COG5464@1|root,COG5464@2|Bacteria,4NGSI@976|Bacteroidetes,1IBPT@117743|Flavobacteriia	976|Bacteroidetes	S	to proteins from other organisms	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
k59_62463_1	323261.Noc_3080	7.77e-55	180.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1WWUT@135613|Chromatiales	135613|Chromatiales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_109871_1	631362.Thi970DRAFT_03296	9.04e-105	308.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,1S518@1236|Gammaproteobacteria,1X0QD@135613|Chromatiales	1236|Gammaproteobacteria	U	Type II secretory pathway, component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_8077_2	1118153.MOY_03408	2.03e-18	77.8	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	The gene assignment is based on its position in a multicopy insertion sequence, directly adjacent to an ORF matching an HMM for the IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_143595_1	1168034.FH5T_02630	1.01e-75	243.0	COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,2FNWH@200643|Bacteroidia	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_69122_1	395493.BegalDRAFT_1181	1.75e-152	436.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,4606E@72273|Thiotrichales	72273|Thiotrichales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
k59_96353_1	1229276.DI53_0535	9.58e-06	47.4	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IVF9@117747|Sphingobacteriia	976|Bacteroidetes	L	DbpA RNA binding domain	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_35705_2	314275.MADE_1014265	1.94e-11	62.4	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,463ZI@72275|Alteromonadaceae	1236|Gammaproteobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
k59_49492_1	1468411.X2KPC6_9CAUD	1.18e-28	110.0	4QH94@10239|Viruses,4QWKQ@35237|dsDNA viruses  no RNA stage,4QTV5@28883|Caudovirales,4QN48@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103625_1	1165841.SULAR_08457	3.45e-49	166.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2YMMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_63009_1	1165841.SULAR_05478	7.09e-65	200.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42R6H@68525|delta/epsilon subdivisions,2YP0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_15525_1	443152.MDG893_07185	2.41e-37	143.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,465RG@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_137380_1	2340.JV46_21930	1.35e-57	180.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_137380_2	1249627.D779_0034	8.32e-34	124.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,1S0ZZ@1236|Gammaproteobacteria,1WX12@135613|Chromatiales	135613|Chromatiales	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9,Response_reg
k59_164545_2	911239.CF149_13822	2.1e-60	197.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k59_171418_1	202952.BBLI01000003_gene280	3.85e-10	57.4	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,3NN5J@468|Moraxellaceae	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_171418_2	1121940.AUDZ01000017_gene2464	8.73e-39	147.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1XIN2@135619|Oceanospirillales	135619|Oceanospirillales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_35713_1	1122176.KB903561_gene3587	3.25e-05	52.8	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,1IWR7@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
k59_8552_1	1125863.JAFN01000001_gene1503	2.53e-05	52.4	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,42UIQ@68525|delta/epsilon subdivisions,2WQAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_191713_1	72658.Bostr.6885s0002.1.p	7.29e-43	151.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,3GBUN@35493|Streptophyta,3HYCY@3699|Brassicales	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)	-	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k59_137387_1	314230.DSM3645_19603	1.83e-48	166.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_59416_2	545264.KB898746_gene812	8.99e-50	159.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales	135613|Chromatiales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_113075_1	316067.Geob_1146	1.97e-23	93.6	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,42W91@68525|delta/epsilon subdivisions,2WRAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
k59_93413_1	1165841.SULAR_02503	5.25e-82	246.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria,42TNP@68525|delta/epsilon subdivisions,2YTE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_93413_2	1165841.SULAR_02498	6.15e-44	147.0	COG1309@1|root,COG1309@2|Bacteria,1R53F@1224|Proteobacteria,42T25@68525|delta/epsilon subdivisions,2YPFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_5412_1	330214.NIDE1537	1.64e-50	172.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	PPC,Peptidase_C14,Sel1
k59_208544_1	247634.GPB2148_3255	1.36e-132	390.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1J4D4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k59_79707_1	279714.FuraDRAFT_0707	7e-117	342.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VH85@28216|Betaproteobacteria,2KQ7T@206351|Neisseriales	206351|Neisseriales	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_214933_1	1123008.KB905692_gene352	6.6e-11	61.6	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,2FM75@200643|Bacteroidia,22W39@171551|Porphyromonadaceae	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_93418_1	2340.JV46_11990	8.86e-103	316.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1J4TI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_120532_1	1165841.SULAR_10349	1.31e-152	448.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_32263_1	997346.HMPREF9374_3033	2.03e-41	155.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,27BER@186824|Thermoactinomycetaceae	91061|Bacilli	Q	cog cog1020	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_93424_1	865937.Gilli_1826	6.48e-39	142.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,1HYEB@117743|Flavobacteriia,2P6B5@244698|Gillisia	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,DUF4301
k59_214943_1	330214.NIDE3169	1.03e-39	135.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_194999_1	643867.Ftrac_3669	1.81e-35	136.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_86527_2	985255.APHJ01000035_gene7	8.99e-51	168.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia,2P6HK@244698|Gillisia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_147598_1	1121875.KB907548_gene1228	7.08e-80	247.0	COG1215@1|root,COG1215@2|Bacteria,4PKBU@976|Bacteroidetes,1HXS3@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
k59_79715_1	1165841.SULAR_05583	2.65e-111	323.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2YMCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_201725_1	1160707.AJIK01000007_gene1164	8.76e-21	94.4	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4HHT7@91061|Bacilli,26I9B@186818|Planococcaceae	91061|Bacilli	T	diguanylate cyclase	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GGDEF
k59_174511_2	2340.JV46_20360	5.06e-78	236.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_174511_3	2340.JV46_20350	5.02e-34	125.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1J5UV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_38525_1	452662.SJA_C2-00800	8.82e-09	58.2	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2UD9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
k59_208561_1	313596.RB2501_06480	7.23e-77	238.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_181224_1	765910.MARPU_15840	9.85e-20	90.5	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X29W@135613|Chromatiales	135613|Chromatiales	NT	chemotaxis	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_181224_2	1163409.UUA_08029	9.12e-28	119.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales	135614|Xanthomonadales	T	Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_188068_1	2340.JV46_19790	1.04e-62	206.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1J4SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Permease	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_66218_1	395493.BegalDRAFT_3347	1.82e-94	298.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,4600P@72273|Thiotrichales	72273|Thiotrichales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_127202_1	1165841.SULAR_07400	3.24e-78	236.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SSI@68525|delta/epsilon subdivisions,2YPDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_93436_1	754477.Q7C_132	2.79e-129	393.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_201732_2	78245.Xaut_1433	3.79e-20	89.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,3F16W@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_59430_1	1165841.SULAR_02748	7.65e-120	358.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_59430_2	1165841.SULAR_02753	1.52e-107	317.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YN8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0191	Fer2_3,Fer4_8
k59_100054_1	1165841.SULAR_06118	9.78e-109	326.0	COG4775@1|root,COG4775@2|Bacteria,1R536@1224|Proteobacteria	1224|Proteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_167758_1	382464.ABSI01000017_gene46	5.95e-54	188.0	COG3507@1|root,COG3507@2|Bacteria,46UI1@74201|Verrucomicrobia,2IVMS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_201742_1	1168289.AJKI01000007_gene209	5e-42	139.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,3XK95@558415|Marinilabiliaceae	976|Bacteroidetes	L	bacterial (prokaryotic) histone like domain	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_161125_1	313596.RB2501_14859	3.94e-82	274.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_127206_2	1123487.KB892865_gene1380	1.89e-62	214.0	COG3170@1|root,COG3170@2|Bacteria,1PMRK@1224|Proteobacteria,2W7ZG@28216|Betaproteobacteria,2KZB6@206389|Rhodocyclales	206389|Rhodocyclales	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45794_1	565045.NOR51B_2046	9.35e-07	50.4	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1J5CG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_45794_2	391615.ABSJ01000012_gene1790	2.27e-57	192.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1J4DV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	iJN746.PP_0104	COX1
k59_161127_1	380358.XALC_1056	1.91e-31	127.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_154190_1	247490.KSU1_D0180	3.49e-34	134.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	rtpR	-	1.1.98.6,1.17.4.1	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC
k59_140553_1	234267.Acid_7565	1.27e-65	213.0	COG2227@1|root,COG2227@2|Bacteria,3Y71H@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_93447_1	1392498.JQLH01000001_gene1176	7.88e-81	252.0	28HNS@1|root,2Z7WY@2|Bacteria,4NDYC@976|Bacteroidetes,1HYVW@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4856)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4856
k59_181239_1	1028803.GG9_0496	1.31e-40	154.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1Y9T1@135625|Pasteurellales	135625|Pasteurellales	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,ResIII
k59_93448_1	313596.RB2501_03760	2.1e-75	250.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IJBA@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_127216_1	32057.KB217472_gene7936	1.69e-47	167.0	COG2251@1|root,COG2251@2|Bacteria,1G03D@1117|Cyanobacteria,1HJ7T@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM RecB family nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,DUF4332,RNase_H_2
k59_107113_1	987059.RBXJA2T_14051	9.46e-22	92.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VMPX@28216|Betaproteobacteria,1KIXZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_107113_2	909663.KI867150_gene185	3.82e-46	155.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,42S9S@68525|delta/epsilon subdivisions,2WNSD@28221|Deltaproteobacteria,2MQQV@213462|Syntrophobacterales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD2	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_174539_1	1168034.FH5T_10050	1.9e-91	273.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,2FMRG@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_53010_1	586413.CCDL010000002_gene1900	2.09e-19	93.2	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,23JT9@182709|Oceanobacillus	91061|Bacilli	L	Bacterial DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_161640_1	1165841.SULAR_05573	3.84e-147	434.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_141072_2	1384056.N787_06230	1.41e-37	143.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,1X47V@135614|Xanthomonadales	135614|Xanthomonadales	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_120992_1	1349785.BAUG01000022_gene1432	9.9e-09	60.8	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
k59_181718_1	1168034.FH5T_21045	1.35e-42	145.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_53015_1	1165841.SULAR_09574	1.28e-48	162.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
k59_46343_3	1385515.N791_04490	1.71e-06	49.7	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1X4ZH@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_127639_1	1165841.SULAR_09214	6.42e-39	132.0	COG1585@1|root,COG1585@2|Bacteria,1QAJG@1224|Proteobacteria,43AB2@68525|delta/epsilon subdivisions,2YQRB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k59_66822_1	118163.Ple7327_3963	1.17e-42	158.0	2BXCB@1|root,2Z8QU@2|Bacteria	2|Bacteria	M	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers	phaZ2	-	3.1.1.22	ko:K07518	ko00650,map00650	-	R00048	RC00037,RC00094	ko00000,ko00001,ko01000	-	-	-	3HBOH
k59_39141_1	903818.KI912268_gene2060	7.43e-75	234.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
k59_107658_1	1122194.AUHU01000003_gene1955	1.6e-69	219.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,1S275@1236|Gammaproteobacteria,466SI@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_107658_2	506534.Rhein_1263	3.34e-43	152.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1WXQU@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_202218_1	2340.JV46_29220	1.12e-86	265.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1J4QH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Permease	perM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
k59_141086_1	1121904.ARBP01000004_gene886	1.6e-38	144.0	COG0204@1|root,COG0204@2|Bacteria,4NJDA@976|Bacteroidetes,47MU0@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_25885_2	5970.XP_009152359.1	7.51e-11	61.6	COG0251@1|root,KOG2317@2759|Eukaryota,3A5RT@33154|Opisthokonta,3P5AT@4751|Fungi,3QVNS@4890|Ascomycota,20HGJ@147545|Eurotiomycetes	4751|Fungi	J	Endoribonuclease L-PSP	-	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006549,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_87000_1	1165841.SULAR_02093	3.34e-49	159.0	COG2193@1|root,COG2193@2|Bacteria,1RF3C@1224|Proteobacteria,431VK@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_87000_2	1121921.KB898707_gene1168	2.9e-39	143.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,2PMXW@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Aminoacyl-tRNA editing domain	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_161657_1	317025.Tcr_1108	3.53e-10	67.8	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1QYKR@1224|Proteobacteria,1T3X5@1236|Gammaproteobacteria,460SR@72273|Thiotrichales	72273|Thiotrichales	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_87004_1	1049564.TevJSym_bu00030	2.89e-05	42.7	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1J5YE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_87004_2	2340.JV46_07410	6.03e-90	265.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1J5QN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_195532_1	929703.KE386491_gene1885	3.29e-39	135.0	COG0242@1|root,COG0242@2|Bacteria,4NMRE@976|Bacteroidetes,47PA5@768503|Cytophagia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_41120_1	1206777.B195_11386	1.15e-19	94.4	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,1T1FF@1236|Gammaproteobacteria,1Z996@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	TonB dependent receptor	irp	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_176656_1	1168034.FH5T_02905	9.17e-29	114.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,2FMQC@200643|Bacteroidia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_135961_1	555779.Dthio_PD0923	2.87e-06	48.9	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2M81M@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_122455_1	519989.ECTPHS_13123	2.68e-32	114.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1WYNJ@135613|Chromatiales	135613|Chromatiales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_122455_2	977880.RALTA_A2929	2.39e-35	124.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,1K77S@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_115684_1	58344.JOEL01000030_gene3014	1.32e-13	79.0	COG3292@1|root,COG3292@2|Bacteria,2HY4Z@201174|Actinobacteria	201174|Actinobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
k59_142775_1	335543.Sfum_3200	8.75e-128	377.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Q0C@68525|delta/epsilon subdivisions,2WIIZ@28221|Deltaproteobacteria,2MRB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
k59_183421_1	1168034.FH5T_04210	1.02e-110	327.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_47865_1	396588.Tgr7_0748	2.12e-40	140.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1WY4I@135613|Chromatiales	135613|Chromatiales	S	NGG1p interacting factor 3	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_47865_2	587753.EY04_04065	5.14e-22	96.7	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	degS	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
k59_34364_1	243231.GSU2262	7.65e-70	223.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	gnnB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2351	DegT_DnrJ_EryC1
k59_169824_1	1046714.AMRX01000008_gene745	2.93e-08	63.9	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_163130_1	28229.ND2E_4082	2.1e-15	77.4	COG3137@1|root,COG3137@2|Bacteria,1RCKQ@1224|Proteobacteria,1S0GK@1236|Gammaproteobacteria,2Q6RK@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
k59_210602_1	1166018.FAES_1522	6.11e-25	107.0	COG4198@1|root,COG4198@2|Bacteria,4PKS3@976|Bacteroidetes	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_88591_1	1168034.FH5T_16915	1.11e-62	205.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_88594_1	2880.D7G909	2.05e-33	131.0	COG0008@1|root,KOG1149@2759|Eukaryota	2759|Eukaryota	J	glutamyl-tRNA aminoacylation	-	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009657,GO:0009658,GO:0009791,GO:0009908,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0034641,GO:0034645,GO:0034660,GO:0035670,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048467,GO:0048481,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0061458,GO:0071704,GO:0071840,GO:0090304,GO:0090567,GO:0099402,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698,ko:K18752	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03009,ko03016,ko03019	1.I.1	-	-	tRNA-synt_1c
k59_183436_1	1189619.pgond44_14943	5.81e-65	209.0	COG3547@1|root,COG3547@2|Bacteria,4NF2F@976|Bacteroidetes,1HXCM@117743|Flavobacteriia,4C2NG@83612|Psychroflexus	976|Bacteroidetes	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_20879_1	526222.Desal_2832	1.56e-104	316.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_482_1	1121405.dsmv_2856	4.4e-145	429.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_88600_1	1122212.AULO01000006_gene1632	6.39e-11	68.6	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XH5K@135619|Oceanospirillales	135619|Oceanospirillales	L	helicase superfamily c-terminal domain	-	-	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
k59_81822_2	1380600.AUYN01000003_gene60	1.9e-10	65.9	COG3307@1|root,COG3307@2|Bacteria,4NGIS@976|Bacteroidetes,1HYGB@117743|Flavobacteriia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k59_176687_1	272123.Anacy_5452	1.2e-86	270.0	COG0076@1|root,COG0076@2|Bacteria,1G3F8@1117|Cyanobacteria	1117|Cyanobacteria	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
k59_61520_1	713586.KB900536_gene1569	2.46e-69	220.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1WWYR@135613|Chromatiales	135613|Chromatiales	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_176689_1	891391.LAC30SC_05040	3.11e-13	70.1	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_190317_1	1134510.O9A_00525	1.65e-17	89.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,48TBN@772|Bartonellaceae	28211|Alphaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
k59_74978_1	1165841.SULAR_00220	3.03e-42	148.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,42SHJ@68525|delta/epsilon subdivisions,2YPQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin,Thioredoxin_8
k59_95350_1	395493.BegalDRAFT_2698	8.09e-34	134.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1QTDW@1224|Proteobacteria,1RXD3@1236|Gammaproteobacteria,461GI@72273|Thiotrichales	72273|Thiotrichales	U	domain, Protein	-	-	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
k59_190319_1	997346.HMPREF9374_3653	6e-53	179.0	COG0451@1|root,COG0451@2|Bacteria,1TPHV@1239|Firmicutes,4HCJR@91061|Bacilli,27CRK@186824|Thermoactinomycetaceae	91061|Bacilli	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_27651_2	768671.ThimaDRAFT_4796	0.000129	50.4	28P52@1|root,2ZC06@2|Bacteria,1QDPX@1224|Proteobacteria,1S1Z6@1236|Gammaproteobacteria,1WY58@135613|Chromatiales	135613|Chromatiales	S	Type II secretion system protein B	-	-	-	ko:K02451	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	T2SSB
k59_14060_1	1198232.CYCME_1995	1.21e-15	75.5	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,45ZYD@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_156443_1	1165841.SULAR_00710	7.84e-132	411.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_129183_1	1254432.SCE1572_37890	1.61e-13	75.9	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,42X2Z@68525|delta/epsilon subdivisions,2WTRX@28221|Deltaproteobacteria,2YTSH@29|Myxococcales	28221|Deltaproteobacteria	FH	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
k59_169860_1	1165841.SULAR_09394	3.11e-94	285.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_190325_1	2340.JV46_28290	3.53e-68	214.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1JBCR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
k59_81827_1	998674.ATTE01000001_gene674	1.65e-60	199.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,46052@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_81827_2	754476.Q7A_2023	3.75e-12	66.2	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_163654_1	1121362.A605_07920	4.33e-19	91.3	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,22K4N@1653|Corynebacteriaceae	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_82353_1	1165841.SULAR_03452	8e-54	179.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_183927_1	765910.MARPU_01725	4.85e-23	94.4	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1WWID@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_68751_1	1165841.SULAR_01385	7.29e-172	481.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2YMW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_68751_2	1165841.SULAR_01380	1.01e-37	131.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2YNF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 1	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_89219_1	102129.Lepto7375DRAFT_1004	9.4e-52	175.0	COG3039@1|root,COG3039@2|Bacteria,1GCCT@1117|Cyanobacteria	1117|Cyanobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_197622_1	1499967.BAYZ01000156_gene568	1.31e-22	102.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria	2|Bacteria	Q	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_977_2	1165841.SULAR_09739	1.31e-65	207.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42QPW@68525|delta/epsilon subdivisions,2YP0Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75474_1	1165841.SULAR_01973	2.9e-128	369.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_75474_2	1165841.SULAR_09219	2.15e-27	107.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_82362_1	387093.SUN_1010	1.59e-15	75.1	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_82362_2	1165841.SULAR_02663	5.19e-46	164.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_89233_1	1499967.BAYZ01000172_gene5764	2.71e-26	115.0	COG0515@1|root,COG2114@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GGDEF,GerE,Guanylate_cyc,HATPase_c,HisKA,PAS_9,Pkinase,Response_reg
k59_986_1	983544.Lacal_2806	8.89e-41	142.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_14591_1	706587.Desti_4553	2.82e-35	138.0	COG1203@1|root,COG1203@2|Bacteria,1MX99@1224|Proteobacteria,42NPE@68525|delta/epsilon subdivisions,2WJKI@28221|Deltaproteobacteria,2MQCE@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	TIGRFAM CRISPR-associated helicase Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
k59_204274_1	338963.Pcar_1709	1.68e-06	53.1	COG3857@1|root,COG3857@2|Bacteria,1Q1TF@1224|Proteobacteria,43EZ0@68525|delta/epsilon subdivisions,2X1XI@28221|Deltaproteobacteria,43S26@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_204274_2	1049564.TevJSym_ad01200	0.000602	41.6	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1J4ZH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_95863_1	313628.LNTAR_14877	9.56e-26	107.0	COG0540@1|root,COG0540@2|Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490,iZ_1308.Z5856	OTCace,OTCace_N
k59_55212_1	1198232.CYCME_0391	9.15e-57	183.0	COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,460P8@72273|Thiotrichales	72273|Thiotrichales	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_55212_2	1122603.ATVI01000006_gene705	5.26e-24	98.6	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1X658@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
k59_177143_1	2340.JV46_03600	6.69e-56	187.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1J54Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_177143_2	314278.NB231_15228	8.43e-65	198.0	COG0347@1|root,COG0347@2|Bacteria,1RIY4@1224|Proteobacteria,1S67U@1236|Gammaproteobacteria,1WYIZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
k59_177143_3	1249627.D779_1733	3.05e-153	463.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_136503_1	1392486.JIAF01000004_gene2264	1.53e-38	149.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia	976|Bacteroidetes	P	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_211186_1	1304888.ATWF01000001_gene1791	6.4e-10	55.1	COG5450@1|root,COG5450@2|Bacteria,2GGN7@200930|Deferribacteres	200930|Deferribacteres	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
k59_995_2	880073.Calab_2556	1.1e-37	127.0	COG3251@1|root,COG3251@2|Bacteria,2NRE2@2323|unclassified Bacteria	2|Bacteria	S	MbtH-like protein	-	-	-	ko:K05375,ko:K09190	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH,YqcI_YcgG
k59_55215_1	1380355.JNIJ01000006_gene3041	1.64e-63	206.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,3JR1M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_106982_2	218851.Aquca_023_00075.1	1.32e-13	69.3	COG1008@1|root,KOG4845@2759|Eukaryota,37KP8@33090|Viridiplantae,3GEAS@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	nad4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03881	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_11595_1	929558.SMGD1_2862	9.01e-116	353.0	COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_5281_1	1123277.KB893194_gene5840	2.86e-32	122.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,47NU5@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
k59_194880_1	1165841.SULAR_07970	2.39e-124	354.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2YN2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_194880_2	1165841.SULAR_07965	6.96e-31	108.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2YQIN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_66077_1	7029.ACYPI073472-PA	3.43e-06	53.1	COG2801@1|root,KOG0017@2759|Eukaryota,39ZX7@33154|Opisthokonta,3BQ45@33208|Metazoa,3D40D@33213|Bilateria,4222J@6656|Arthropoda,3SQHH@50557|Insecta	33208|Metazoa	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_208446_1	4565.Traes_2AL_A313D8886.1	7.76e-67	208.0	29XCM@1|root,2RXRI@2759|Eukaryota,37U8V@33090|Viridiplantae,3GHWM@35493|Streptophyta,3KZGB@4447|Liliopsida,3IHE6@38820|Poales	35493|Streptophyta	S	ATP synthase protein YMF19	atp8	GO:0000276,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005773,GO:0009507,GO:0009536,GO:0016020,GO:0016469,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033177,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045259,GO:0045263,GO:0046872,GO:0046914,GO:0050897,GO:0098796,GO:0098798,GO:0098800	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	DUF1082,YMF19
k59_187939_1	1265505.ATUG01000001_gene4787	3.45e-23	97.8	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2WJYS@28221|Deltaproteobacteria,2MI4W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_187939_2	1121405.dsmv_2060	1.06e-26	106.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria,2MJNM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_201563_1	387093.SUN_0648	3.57e-102	305.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_99976_1	1165841.SULAR_08257	2.17e-161	467.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
k59_99976_2	1165841.SULAR_08252	1.22e-132	380.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_147474_1	1448857.JFAP01000007_gene312	1.66e-10	63.9	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,43B2E@68525|delta/epsilon subdivisions,2YN33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidylprolyl isomerase	peb4	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_147474_2	313612.L8106_23705	1.02e-09	58.5	COG2173@1|root,COG2173@2|Bacteria,1G07K@1117|Cyanobacteria,1H8T7@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
k59_25183_1	247639.MGP2080_12023	5.14e-68	221.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1J57E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_154089_1	349521.HCH_05230	1.31e-26	102.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,1S70H@1236|Gammaproteobacteria,1XKFQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Invasion gene expression up-regulator	-	-	-	-	-	-	-	-	-	-	-	-	SirB
k59_93280_1	1168034.FH5T_09685	2.97e-26	101.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,2FMTB@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
k59_93280_2	880070.Cycma_0956	3.21e-05	48.5	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,47NQ9@768503|Cytophagia	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_167602_1	1132836.RCCGE510_20779	2.66e-93	292.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_181140_1	1150626.PHAMO_290092	3.44e-13	71.6	COG1102@1|root,COG1102@2|Bacteria,1RGPZ@1224|Proteobacteria,2U7QU@28211|Alphaproteobacteria,2JSJK@204441|Rhodospirillales	204441|Rhodospirillales	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_167605_1	2340.JV46_17410	3.44e-111	333.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_194892_1	1382359.JIAL01000001_gene2795	1.82e-57	194.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_45640_1	243090.RB9308	2.04e-50	178.0	COG1538@1|root,COG1538@2|Bacteria,2IYRU@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_99979_1	1493510.A0A0E3F5A9_9CAUD	5.72e-06	55.1	4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae	10662|Myoviridae	S	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_147484_1	1165841.SULAR_05603	1.06e-111	330.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2YMR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_32181_1	653045.Strvi_5195	1e-42	160.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Beta-lactamase,Condensation,PP-binding
k59_140411_1	2340.JV46_23450	2.19e-26	106.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1J4QB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0281 Malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_140411_2	1255043.TVNIR_0227	2.28e-30	108.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales	135613|Chromatiales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_59293_1	1165841.SULAR_03188	6.13e-91	275.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_52363_1	99598.Cal7507_1449	1.85e-47	155.0	COG4634@1|root,COG4634@2|Bacteria,1G8JH@1117|Cyanobacteria,1HQAA@1161|Nostocales	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
k59_52363_2	575540.Isop_2412	8.17e-06	45.8	COG2442@1|root,COG2442@2|Bacteria,2J1H3@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
k59_25198_1	1250232.JQNJ01000001_gene2502	9.03e-109	330.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_73051_1	1049564.TevJSym_aa00830	8.78e-41	141.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,1J71P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_59687_1	1117318.PRUB_11666	1.15e-15	75.1	2BU8D@1|root,32PHV@2|Bacteria,1NANB@1224|Proteobacteria,1SFYJ@1236|Gammaproteobacteria,2Q3D1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
k59_5646_1	1165841.SULAR_03772	2.68e-115	349.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2YMAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_147815_1	948565.AFFP02000001_gene1165	5.46e-29	122.0	COG2369@1|root,COG2369@2|Bacteria,1PH12@1224|Proteobacteria,1T6BN@1236|Gammaproteobacteria,1Y9TA@135625|Pasteurellales	135625|Pasteurellales	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_79876_1	326298.Suden_0621	1.96e-61	197.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42PYD@68525|delta/epsilon subdivisions,2YN6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k59_181409_1	1267535.KB906767_gene5244	1.84e-27	115.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
k59_100267_1	1090318.ATTI01000001_gene3129	2.09e-87	262.0	COG2310@1|root,COG2310@2|Bacteria,1N1IX@1224|Proteobacteria,2TS9X@28211|Alphaproteobacteria,2K244@204457|Sphingomonadales	204457|Sphingomonadales	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
k59_52725_1	1165841.SULAR_00540	1.27e-83	249.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2YP4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_25532_1	697282.Mettu_3266	6.09e-111	322.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1XEGX@135618|Methylococcales	135618|Methylococcales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_154376_1	1168065.DOK_16998	2.64e-48	156.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,1S6AM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_154376_2	344747.PM8797T_00407	1.63e-14	70.1	COG3070@1|root,COG3070@2|Bacteria,2J0Y3@203682|Planctomycetes	203682|Planctomycetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
k59_215164_1	595460.RRSWK_03372	4.85e-31	126.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_100268_1	498211.CJA_0002	1.69e-69	226.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1FG21@10|Cellvibrio	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_52729_1	1380387.JADM01000007_gene665	1.23e-48	171.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XHRM@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_188295_1	1123401.JHYQ01000005_gene256	1.23e-85	262.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,461RN@72273|Thiotrichales	72273|Thiotrichales	G	Glucokinase	-	-	-	-	-	-	-	-	-	-	-	-	Glucokinase
k59_73068_1	4081.Solyc01g007640.2.1	9.38e-108	346.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_66536_1	391038.Bphy_1748	4.74e-36	140.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,1K1P9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_120830_1	572480.Arnit_0838	6.11e-43	150.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2YPQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
k59_120830_2	367737.Abu_2150	2.7e-48	160.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2YP0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_93648_1	1336233.JAEH01000013_gene3464	4.63e-64	217.0	COG0457@1|root,COG0457@2|Bacteria,1PBYW@1224|Proteobacteria,1SWS0@1236|Gammaproteobacteria,2QDGR@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_127420_1	305900.GV64_19805	1.72e-17	88.2	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1XH98@135619|Oceanospirillales	135619|Oceanospirillales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_5674_1	314285.KT71_003846	1.62e-70	217.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria	1224|Proteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_38810_1	398767.Glov_3465	6.53e-83	274.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,43TI4@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_100282_1	2340.JV46_05690	1.96e-102	308.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1JBRQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_107345_1	2340.JV46_24660	1.25e-52	172.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,1S42J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_195256_1	395493.BegalDRAFT_0326	2.9e-39	142.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,461U7@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin	-	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_195256_2	7739.XP_002590720.1	4.83e-24	93.2	2CZEB@1|root,2S9YW@2759|Eukaryota,3AB3P@33154|Opisthokonta,3BUXI@33208|Metazoa,3DB54@33213|Bilateria	33208|Metazoa	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_25561_1	1254432.SCE1572_35625	3.79e-11	63.2	COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,42VD2@68525|delta/epsilon subdivisions,2WRMS@28221|Deltaproteobacteria,2Z0FP@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_25561_2	1307437.J139_15427	5.61e-26	102.0	29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,1SB4D@1236|Gammaproteobacteria,2Q34Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
k59_168057_2	765913.ThidrDRAFT_0748	6.88e-22	95.5	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales	135613|Chromatiales	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
k59_52751_1	1461580.CCAS010000037_gene3098	7.6e-34	128.0	COG2021@1|root,COG2021@2|Bacteria,1V0J9@1239|Firmicutes,4HCZZ@91061|Bacilli,1ZSGS@1386|Bacillus	91061|Bacilli	E	alpha/beta hydrolase fold	estA3	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_181433_2	67257.JODR01000013_gene6238	1.23e-09	63.9	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	accA2	-	6.4.1.1,6.4.1.3,6.4.1.4	ko:K01959,ko:K01965,ko:K01968	ko00020,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01130,ko01200,ko01230,map00020,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01130,map01200,map01230	M00036,M00173,M00373,M00620,M00741	R00344,R01859,R04138	RC00040,RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0973c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_25568_1	395493.BegalDRAFT_3357	5.6e-40	145.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,1RNUW@1236|Gammaproteobacteria,463EF@72273|Thiotrichales	1224|Proteobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
k59_215197_1	395493.BegalDRAFT_0032	6.34e-57	188.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_124417_1	1165841.SULAR_07710	5.38e-128	372.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_158377_2	1165841.SULAR_06138	1.62e-31	112.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SJM@68525|delta/epsilon subdivisions,2YPJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_205820_1	32042.PstZobell_05523	6.54e-06	54.3	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1	comC	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
k59_50076_1	748658.KB907313_gene2317	8.24e-69	221.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1WWZ0@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_199205_1	1168034.FH5T_10400	1.25e-96	309.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes,2FM1V@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_70061_1	768671.ThimaDRAFT_0126	1.79e-44	162.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales	135613|Chromatiales	G	pfam mofrl	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
k59_124421_1	1026955.F5B412_9CAUD	3.09e-165	503.0	4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses  no RNA stage,4QPWY@28883|Caudovirales,4QHVQ@10662|Myoviridae	10662|Myoviridae	S	nucleotide binding	-	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	-
k59_36183_1	313596.RB2501_04555	2.1e-148	447.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1HX66@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_192229_1	1165841.SULAR_01165	1.94e-14	73.9	COG4886@1|root,COG4886@2|Bacteria,1R9FD@1224|Proteobacteria,42XXN@68525|delta/epsilon subdivisions,2YQP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Leucine Rich repeats (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
k59_192229_2	1165841.SULAR_01175	2.76e-68	211.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
k59_104174_1	1165841.SULAR_05448	5.76e-106	325.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_144633_1	1165841.SULAR_09534	2.79e-143	406.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2YM7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_144633_2	1165841.SULAR_09529	3.96e-41	137.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2YPEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_2521_1	378806.STAUR_0742	2.61e-41	146.0	COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria	1224|Proteobacteria	Q	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_151555_1	1170562.Cal6303_3041	4.74e-137	407.0	COG2433@1|root,COG2433@2|Bacteria,1G93F@1117|Cyanobacteria,1HTA7@1161|Nostocales	1117|Cyanobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_104176_1	1382359.JIAL01000001_gene2059	2.59e-46	160.0	COG1060@1|root,COG1060@2|Bacteria,3Y677@57723|Acidobacteria,2JKTA@204432|Acidobacteriia	204432|Acidobacteriia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_104176_2	479433.Caci_5825	1.52e-23	99.8	COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria	201174|Actinobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9210_1	314292.VAS14_06303	4.37e-42	148.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XTZN@135623|Vibrionales	135623|Vibrionales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_9210_2	998674.ATTE01000001_gene425	3.68e-40	143.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_36187_1	29730.Gorai.013G213000.1	1.2e-67	218.0	COG0056@1|root,KOG1353@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit alpha	atp1	-	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_70068_1	1165841.SULAR_01180	9.9e-99	287.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM SEC-C motif domain protein	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_151557_2	1165841.SULAR_09929	7.69e-53	175.0	COG2857@1|root,COG2857@2|Bacteria,1PX4N@1224|Proteobacteria,42MFF@68525|delta/epsilon subdivisions,2YMBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ubiquinol cytochrome c oxidoreductase, cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	iIT341.HP1538	Cytochrom_C,Cytochrom_C1
k59_29592_1	1165841.SULAR_10604	2.11e-88	261.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2YP3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_29592_2	1165841.SULAR_10599	2.88e-11	61.6	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria	1224|Proteobacteria	NU	ErfK ybiS ycfS ynhG family protein	IV02_27405	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_151565_1	1165841.SULAR_06393	1.58e-77	236.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2YM9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_50411_2	1165841.SULAR_08070	3.85e-101	293.0	COG2346@1|root,COG2346@2|Bacteria,1Q5UZ@1224|Proteobacteria,42U39@68525|delta/epsilon subdivisions,2YPTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_185705_1	402881.Plav_1750	9.4e-26	103.0	COG3217@1|root,COG3217@2|Bacteria,1MVSP@1224|Proteobacteria,2U1ST@28211|Alphaproteobacteria,1JNW1@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	MOSC domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
k59_185705_2	998674.ATTE01000001_gene3043	2.91e-25	97.8	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1S69A@1236|Gammaproteobacteria,460MJ@72273|Thiotrichales	72273|Thiotrichales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_124801_1	1500893.JQNB01000001_gene1545	6.82e-12	65.1	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,1RXYM@1236|Gammaproteobacteria,1X3GY@135614|Xanthomonadales	135614|Xanthomonadales	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
k59_165309_1	550540.Fbal_0253	3.56e-59	186.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_30058_1	1165841.SULAR_09624	6.81e-33	119.0	COG2755@1|root,COG2755@2|Bacteria,1RHMJ@1224|Proteobacteria,42VVK@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_30058_2	387093.SUN_1501	2.34e-71	226.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2YNPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_111148_1	1165841.SULAR_05808	3.29e-127	371.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_118222_1	555079.Toce_1366	6.65e-20	94.4	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,42FKT@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
k59_9618_1	879212.DespoDRAFT_01896	1.58e-56	191.0	COG5659@1|root,COG5659@2|Bacteria,1MXSA@1224|Proteobacteria,433H7@68525|delta/epsilon subdivisions,2WXZP@28221|Deltaproteobacteria,2MP9M@213118|Desulfobacterales	1224|Proteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_145134_1	2340.JV46_22310	2.46e-73	233.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1J4RZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	iSDY_1059.SDY_4251	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_30063_1	313596.RB2501_03255	2.52e-81	244.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1I1AX@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_43332_1	1165841.SULAR_09749	2.25e-100	301.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_118225_1	7070.TC008562-PA	1.21e-28	118.0	COG2801@1|root,KOG0017@2759|Eukaryota,39ZX7@33154|Opisthokonta,3BQ45@33208|Metazoa,3D40D@33213|Bilateria,4222J@6656|Arthropoda,3SQHH@50557|Insecta	33208|Metazoa	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_172252_1	1254432.SCE1572_17105	3.65e-65	216.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_91040_1	2340.JV46_29010	4.25e-38	145.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
k59_178801_1	47716.JOFH01000035_gene4089	4.14e-34	134.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,PP-binding,Thioesterase
k59_70523_1	1173264.KI913949_gene1449	1.61e-33	132.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H72F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_84272_1	929558.SMGD1_0413	8.54e-105	311.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,42Q1Y@68525|delta/epsilon subdivisions,2YNR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_70526_2	1165841.SULAR_09459	5.17e-85	253.0	2AMMX@1|root,31CI0@2|Bacteria,1Q8WA@1224|Proteobacteria,42UGB@68525|delta/epsilon subdivisions,2YPW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_16340_1	272624.lpg2421	5.26e-38	137.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,1JFMM@118969|Legionellales	118969|Legionellales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_30078_2	1165841.SULAR_06048	0.000139	46.6	COG1477@1|root,COG1477@2|Bacteria,1PFA4@1224|Proteobacteria,42S5P@68525|delta/epsilon subdivisions,2YPB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_23120_1	1165841.SULAR_01573	3.9e-115	338.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42YUF@68525|delta/epsilon subdivisions,2YR9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_70527_1	1144343.PMI41_01882	1.69e-11	72.4	COG3566@1|root,COG3566@2|Bacteria,1REIQ@1224|Proteobacteria,2U9XH@28211|Alphaproteobacteria,43JI4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2213)	-	-	-	ko:K09960	-	-	-	-	ko00000	-	-	-	DUF2213
k59_36480_1	272134.KB731325_gene631	1.03e-63	213.0	COG3385@1|root,COG3385@2|Bacteria,1G2NV@1117|Cyanobacteria,1HEUG@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1,DDE_Tnp_2
k59_77413_1	1165841.SULAR_05188	2.76e-46	159.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2YMKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_30083_1	1347342.BN863_30540	3.95e-12	68.6	COG1305@1|root,COG1305@2|Bacteria,4NF4N@976|Bacteroidetes,1I0MX@117743|Flavobacteriia	976|Bacteroidetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_30083_2	156889.Mmc1_0394	1.15e-22	102.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,2TRJE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	MA20_16190	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_84282_1	523791.Kkor_0946	3.78e-31	123.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1XH7G@135619|Oceanospirillales	135619|Oceanospirillales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_118247_1	204669.Acid345_2640	6.92e-23	103.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_2,Abhydrolase_4,Esterase
k59_172265_1	517417.Cpar_0326	1.3e-43	160.0	COG1067@1|root,COG1067@2|Bacteria,1FETE@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S16 lon domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_30086_1	1165841.SULAR_04798	5.24e-13	67.8	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_30086_2	1165841.SULAR_04793	2.45e-48	166.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_199553_1	96561.Dole_1421	3.65e-37	140.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42NWQ@68525|delta/epsilon subdivisions,2WM5R@28221|Deltaproteobacteria,2MJ8Y@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,PAS,PAS_4
k59_91052_1	1455076.W6PPK7_9CAUD	2.3e-27	107.0	4QEFP@10239|Viruses,4QZ30@35237|dsDNA viruses  no RNA stage,4QS4Z@28883|Caudovirales,4QP1I@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70540_1	1168034.FH5T_11955	4.04e-64	197.0	COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,2FSSH@200643|Bacteroidia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_30098_1	326442.PSHAa2811	1.58e-56	180.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,2Q25W@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_50439_1	1122201.AUAZ01000028_gene169	2.15e-45	155.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,4658I@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074	Metallophos
k59_50439_2	686578.AFFX01000003_gene423	7.6e-13	64.3	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Redox protein regulator of disulfide bond formation	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_131603_1	314287.GB2207_11203	1.6e-37	132.0	COG0457@1|root,COG0457@2|Bacteria,1QVJZ@1224|Proteobacteria,1T372@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
k59_122397_1	870187.Thini_4318	7.42e-12	67.8	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZNC@72273|Thiotrichales	1236|Gammaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_34309_1	234267.Acid_1602	4.76e-57	192.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
k59_34309_2	1293047.CBMA010000042_gene2620	4.25e-15	79.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23SIE@183963|Halobacteria	183963|Halobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_20807_1	1165841.SULAR_00690	6.8e-95	304.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_81748_1	443152.MDG893_09035	2.66e-62	206.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,464W8@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_419_1	479434.Sthe_0471	1e-38	133.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi,27YD2@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_149517_1	1165841.SULAR_02333	3.08e-195	560.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GGDEF,PAS_9,dCache_3
k59_135911_1	1165841.SULAR_02513	2.5e-93	287.0	COG0834@1|root,COG1073@1|root,COG0834@2|Bacteria,COG1073@2|Bacteria,1N3ZN@1224|Proteobacteria,42VWV@68525|delta/epsilon subdivisions	1224|Proteobacteria	ET	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_135923_1	768671.ThimaDRAFT_1251	1.74e-30	115.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1WW0T@135613|Chromatiales	135613|Chromatiales	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_135923_2	292.DM42_1556	1.87e-107	322.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,1K11D@119060|Burkholderiaceae	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_115633_1	469595.CSAG_03355	2.77e-38	148.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,3WWBT@544|Citrobacter	1236|Gammaproteobacteria	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
k59_34697_3	313596.RB2501_02120	3.18e-24	99.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1HWMN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_122749_1	998674.ATTE01000001_gene2965	2.3e-82	253.0	COG0697@1|root,COG0697@2|Bacteria,1NDKG@1224|Proteobacteria,1S87V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_21171_1	395493.BegalDRAFT_2007	1.87e-52	177.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,1RUDN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_21171_2	754476.Q7A_1079	1.05e-44	155.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,4601V@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_143093_1	180332.JTGN01000024_gene1707	1.18e-27	115.0	COG0407@1|root,COG0407@2|Bacteria	180332.JTGN01000024_gene1707|-	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102484_1	1165841.SULAR_08000	4.01e-42	143.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2YN05@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_102484_2	1165841.SULAR_08005	3e-69	209.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2YPJZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_210949_2	1165841.SULAR_01748	2.13e-67	209.0	2A067@1|root,30N97@2|Bacteria,1Q1X8@1224|Proteobacteria,42UM9@68525|delta/epsilon subdivisions,2YPYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109231_2	2340.JV46_26320	1.51e-42	140.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1J6G6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_41454_1	497321.C664_00580	9.24e-49	168.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VM8B@28216|Betaproteobacteria,2KW9Z@206389|Rhodocyclales	206389|Rhodocyclales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_48232_1	1116472.MGMO_45c00250	2.29e-34	128.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1RN84@1236|Gammaproteobacteria,1XFKN@135618|Methylococcales	135618|Methylococcales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_82192_1	1121481.AUAS01000004_gene1656	1.83e-41	157.0	COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,47Y6J@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_82192_2	1123248.KB893332_gene2259	1.35e-71	242.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_27955_1	306281.AJLK01000042_gene5266	1.35e-31	127.0	COG0784@1|root,COG3437@1|root,COG5000@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG5000@2|Bacteria,1GHJE@1117|Cyanobacteria,1JI33@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_116058_1	760732.E5E470_9CAUD	2.96e-41	142.0	4QCXM@10239|Viruses,4QZZ5@35237|dsDNA viruses  no RNA stage,4QT8U@28883|Caudovirales,4QJ27@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_170235_1	589865.DaAHT2_0964	3.46e-57	194.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MHSK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	-	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_170235_2	573413.Spirs_4003	1.14e-117	356.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_190656_1	1448139.AI20_04950	5e-80	253.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,1Y3Y6@135624|Aeromonadales	135624|Aeromonadales	M	mannose-6-phosphate isomerase type	-	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_7479_1	1056820.KB900696_gene4099	2.24e-82	251.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,2PMK2@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Aldo/keto reductase family	dkgA	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988	Aldo_ket_red
k59_143133_1	1165841.SULAR_05158	1.42e-105	319.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_95650_1	1122132.AQYH01000002_gene1283	1.74e-71	233.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,4BAGU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_183780_1	396588.Tgr7_3049	1.26e-17	76.6	COG5481@1|root,COG5481@2|Bacteria	2|Bacteria	S	small protein containing a coiled-coil domain	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
k59_183780_2	360910.BAV3226	6.35e-44	152.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,3T1HY@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_136325_1	1033802.SSPSH_003092	8.2e-74	224.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_136325_2	203122.Sde_0972	5.81e-28	103.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,467UW@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_7481_1	247639.MGP2080_08861	1.76e-108	327.0	COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,1SVEG@1236|Gammaproteobacteria,1JC1B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
k59_34721_1	1479238.JQMZ01000001_gene2534	6.01e-29	115.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,43WVR@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k59_170250_1	211165.AJLN01000149_gene6650	1.97e-58	207.0	COG0500@1|root,COG3321@1|root,COG2226@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1JKSY@1189|Stigonemataceae	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_813_1	156889.Mmc1_3257	5.55e-14	74.7	28T0P@1|root,2ZF9Z@2|Bacteria,1RAUV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68624_1	926560.KE387026_gene4298	2.21e-30	114.0	COG0336@1|root,COG0336@2|Bacteria,1WIZS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_163529_2	7668.SPU_001651-tr	1.24e-35	136.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_183792_1	382464.ABSI01000011_gene3161	5.94e-07	51.6	COG0715@1|root,COG0715@2|Bacteria,46XR6@74201|Verrucomicrobia,2IWEK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,OmpA
k59_190677_1	1121898.Q766_14565	1.13e-38	132.0	COG0614@1|root,COG0614@2|Bacteria,4NRTJ@976|Bacteroidetes,1IJ3W@117743|Flavobacteriia,2P0IS@237|Flavobacterium	976|Bacteroidetes	P	GxxExxY protein	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
k59_89027_1	1038860.AXAP01000016_gene2172	1.45e-13	70.9	COG2114@1|root,COG4753@1|root,COG2114@2|Bacteria,COG4753@2|Bacteria,1PYP4@1224|Proteobacteria,2TVEP@28211|Alphaproteobacteria,3JVII@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
k59_89027_2	1313301.AUGC01000010_gene936	7.83e-24	102.0	COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
k59_61853_1	391625.PPSIR1_26758	3.24e-40	153.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YWMT@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_102523_2	42565.FP66_13245	4.14e-19	87.4	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1XH4F@135619|Oceanospirillales	135619|Oceanospirillales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_102523_3	216596.pRL120546	6.7e-27	104.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TUSA@28211|Alphaproteobacteria,4B809@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_48278_1	317936.Nos7107_0638	2.35e-57	187.0	COG1397@1|root,COG1397@2|Bacteria,1G3YE@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_197430_1	1168034.FH5T_08605	4.46e-66	203.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,2FU39@200643|Bacteroidia	976|Bacteroidetes	S	Acetyltransferase, gnat family	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k59_177000_1	1238450.VIBNISOn1_1130006	1.17e-60	196.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,1XUEH@135623|Vibrionales	135623|Vibrionales	P	ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_89037_1	1165841.SULAR_01410	1.56e-51	165.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,42S81@68525|delta/epsilon subdivisions,2YPD7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_89037_2	1165841.SULAR_01415	9.85e-52	164.0	COG0477@1|root,COG2814@2|Bacteria,1NH45@1224|Proteobacteria,42VV0@68525|delta/epsilon subdivisions,2YQIW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
k59_61858_1	1165841.SULAR_10059	1.1e-17	82.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42NNF@68525|delta/epsilon subdivisions,2YMDJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_55064_1	349521.HCH_05414	3.62e-22	95.5	COG2304@1|root,COG2304@2|Bacteria,1RGCN@1224|Proteobacteria,1S5GI@1236|Gammaproteobacteria,1XPSH@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k59_55064_2	349521.HCH_05415	6.11e-12	64.7	COG0715@1|root,COG0715@2|Bacteria,1QU25@1224|Proteobacteria,1RZKU@1236|Gammaproteobacteria,1XKDD@135619|Oceanospirillales	135619|Oceanospirillales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
k59_156744_1	1488328.JMCL01000104_gene3971	1.52e-23	103.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_7,PAS_8,Response_reg
k59_122795_1	399739.Pmen_3436	7.14e-16	79.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1YFC8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	BCCT, betaine/carnitine/choline family transporter	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k59_122795_2	89187.ISM_11105	1.16e-22	96.7	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2TRJ3@28211|Alphaproteobacteria,46P4M@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0687 Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_31867_2	387093.SUN_2352	2.08e-33	118.0	COG2259@1|root,COG2259@2|Bacteria,1RKEE@1224|Proteobacteria,42SF5@68525|delta/epsilon subdivisions,2YPGK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_5001_1	270374.MELB17_00915	1.68e-22	95.5	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,4651Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_153851_1	521045.Kole_0975	6.94e-09	68.6	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	HSP70,OmpA,VWA
k59_32295_1	1234364.AMSF01000015_gene3277	5.56e-50	176.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1X46J@135614|Xanthomonadales	135614|Xanthomonadales	FP	Belongs to the GppA Ppx family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_93453_1	1165841.SULAR_07645	2.11e-35	131.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,42P2P@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	phosphotransferase system, EIIB	nagE	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0015764,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0090563,GO:0090586,GO:1901264	2.7.1.193	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	iECP_1309.ECP_0691	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k59_93453_2	1165841.SULAR_07640	6.26e-41	149.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
k59_66263_1	1168034.FH5T_15040	5.78e-86	261.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,2FNJ0@200643|Bacteroidia	976|Bacteroidetes	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_66263_2	1168034.FH5T_15045	2.35e-05	46.2	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,2FKYJ@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_52504_1	1321774.HMPREF9108_00623	3.34e-89	273.0	COG0180@1|root,COG0180@2|Bacteria,37854@32066|Fusobacteria	32066|Fusobacteria	J	Psort location Cytoplasmic, score	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_195032_1	637390.AFOH01000078_gene2661	3.3e-34	122.0	COG4113@1|root,COG4113@2|Bacteria,1N169@1224|Proteobacteria,1SIUZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_195032_2	933262.AXAM01000014_gene244	9.54e-29	104.0	COG2161@1|root,COG2161@2|Bacteria,1NJEG@1224|Proteobacteria,431BG@68525|delta/epsilon subdivisions,2WWDW@28221|Deltaproteobacteria,2MNUD@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_181251_1	765912.Thimo_1740	5.09e-84	266.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales	135613|Chromatiales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_59467_1	2340.JV46_23330	1.55e-23	92.8	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1J5P3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_59467_2	713587.THITH_03885	2.12e-45	149.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1WYAT@135613|Chromatiales	135613|Chromatiales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_32304_1	387093.SUN_0532	1.65e-121	368.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,43CM6@68525|delta/epsilon subdivisions,2YTE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_120596_1	1123401.JHYQ01000013_gene611	4.03e-60	201.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,45ZMK@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_120596_2	1121403.AUCV01000019_gene3264	2.32e-14	70.1	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,42Y1T@68525|delta/epsilon subdivisions,2WSZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
k59_66271_1	498211.CJA_2509	7.93e-10	67.0	COG3210@1|root,COG3210@2|Bacteria,1QQD4@1224|Proteobacteria,1RZ1D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201784_1	1123518.ARWI01000001_gene475	2.79e-105	322.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,461JZ@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_195036_1	196367.JNFG01000201_gene2959	5.13e-66	218.0	COG0436@1|root,COG0436@2|Bacteria,1QE0D@1224|Proteobacteria,2VIUB@28216|Betaproteobacteria,1K0XZ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	asdA	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_79746_1	2340.JV46_26050	8.82e-33	121.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1J9IK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_79746_2	1133850.SHJG_5895	1.8e-06	51.2	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
k59_59475_1	398720.MED217_00680	3.25e-15	73.9	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,2XIWT@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Glutamine amidotransferase domain	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_59475_2	1249997.JHZW01000002_gene1374	6.38e-33	128.0	28IHD@1|root,2Z8IK@2|Bacteria,4NF9V@976|Bacteroidetes,1HY20@117743|Flavobacteriia,2PH6P@252356|Maribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
k59_181255_1	395493.BegalDRAFT_1058	8.84e-87	288.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
k59_38576_1	1165841.SULAR_08719	3.1e-94	287.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42YXJ@68525|delta/epsilon subdivisions,2YR3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
k59_86562_1	876044.IMCC3088_2206	1.04e-148	424.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_154209_2	1026882.MAMP_00505	6.65e-51	172.0	COG1133@1|root,COG1133@2|Bacteria,1QU39@1224|Proteobacteria,1T1PR@1236|Gammaproteobacteria,460NC@72273|Thiotrichales	72273|Thiotrichales	I	SbmA/BacA-like family	-	-	-	-	-	-	-	-	-	-	-	-	SbmA_BacA
k59_59479_1	481448.Minf_1950	1.05e-34	128.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_59479_2	1396418.BATQ01000137_gene3864	0.000584	42.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,2ITKY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
k59_32316_1	215803.DB30_2605	1.76e-34	136.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria,2YTXM@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19,TPR_8,Transglut_core
k59_18881_1	1121927.GOHSU_12_00470	1.7e-10	74.3	COG0515@1|root,COG5184@1|root,COG0515@2|Bacteria,COG5184@2|Bacteria,2IG31@201174|Actinobacteria,4GCNZ@85026|Gordoniaceae	201174|Actinobacteria	DKLTZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Flg_new,Pkinase,RCC1,RCC1_2
k59_25321_1	1313421.JHBV01000024_gene4946	2.95e-29	117.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1IP4P@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_120621_1	1165841.SULAR_05193	1.78e-72	241.0	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_59489_1	767817.Desgi_2849	0.000398	48.1	COG0471@1|root,COG0664@1|root,COG0683@1|root,COG0471@2|Bacteria,COG0664@2|Bacteria,COG0683@2|Bacteria,1TSDD@1239|Firmicutes,2483T@186801|Clostridia,261BJ@186807|Peptococcaceae	186801|Clostridia	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_188143_1	1408473.JHXO01000005_gene1444	1.41e-67	213.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,2FMSI@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_208636_1	247634.GPB2148_3317	6.6e-80	261.0	COG2198@1|root,COG2198@2|Bacteria,1NQDP@1224|Proteobacteria,1RXD0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_127274_2	545264.KB898752_gene2383	5.72e-40	150.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_52542_1	406817.XNC1_3632	2.41e-109	328.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_154219_1	1236959.BAMT01000001_gene1038	9.54e-99	315.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,2KKQ5@206350|Nitrosomonadales	206350|Nitrosomonadales	EF	PFAM Carbamoyl-phosphate synthase L chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_11805_2	1349785.BAUG01000135_gene2872	1.05e-65	206.0	COG3335@1|root,COG3335@2|Bacteria,4NR21@976|Bacteroidetes,1I35Q@117743|Flavobacteriia	976|Bacteroidetes	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_174592_2	1165841.SULAR_04102	1.58e-82	249.0	COG2928@1|root,COG2928@2|Bacteria	2|Bacteria	S	Conserved Protein	YH67_14670	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_134198_1	1165841.SULAR_10149	2.04e-104	322.0	COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,43BSV@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_140623_1	1265313.HRUBRA_01296	1.92e-67	221.0	COG4145@1|root,COG4145@2|Bacteria,1QYUD@1224|Proteobacteria,1RZPW@1236|Gammaproteobacteria,1J8XU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_25342_1	595460.RRSWK_00694	0.000367	48.5	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_208639_1	1165841.SULAR_09394	7.34e-104	310.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_38617_1	1123228.AUIH01000102_gene3067	2.8e-87	266.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,1RQQA@1236|Gammaproteobacteria,1XKYJ@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_59520_1	1165841.SULAR_10164	1.38e-38	144.0	COG0642@1|root,COG0642@2|Bacteria,1PZPT@1224|Proteobacteria,42QYI@68525|delta/epsilon subdivisions,2YP31@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,HisKA
k59_59520_2	563040.Saut_1715	1.52e-06	49.7	COG0745@1|root,COG0745@2|Bacteria,1Q6G8@1224|Proteobacteria,42T3T@68525|delta/epsilon subdivisions,2YPQK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_174603_2	1501391.LG35_05925	1.75e-26	110.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22V8H@171550|Rikenellaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
k59_72932_2	1280950.HJO_09889	8.47e-12	65.1	COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,2U9G0@28211|Alphaproteobacteria,43XRK@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_59523_1	1121918.ARWE01000001_gene2377	1.91e-62	206.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_140635_1	1165841.SULAR_05568	4.22e-10	59.3	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_140635_2	1165841.SULAR_05563	1.23e-84	259.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2YMD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	2-nitropropane dioxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_107175_1	1123355.JHYO01000027_gene2096	1.11e-80	251.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2U05W@28211|Alphaproteobacteria,36YNH@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k59_181292_1	56107.Cylst_5566	2.92e-139	417.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1HJE5@1161|Nostocales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_201846_2	1300345.LF41_881	5.4e-05	50.4	2DKZK@1|root,310GY@2|Bacteria,1NQ6H@1224|Proteobacteria,1SSKG@1236|Gammaproteobacteria,1X6D8@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
k59_100121_1	1165841.SULAR_09684	4.85e-133	381.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2YMKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_195071_1	1286106.MPL1_00732	2.37e-34	128.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,460EH@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_59528_1	83219.PM02_04635	8.11e-81	252.0	COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,2TUN2@28211|Alphaproteobacteria,3ZVZ1@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
k59_118918_1	1165841.SULAR_04542	5.98e-88	270.0	COG1538@1|root,COG1538@2|Bacteria,1PBTH@1224|Proteobacteria,42R59@68525|delta/epsilon subdivisions,2YP2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_30666_1	1283300.ATXB01000001_gene603	1.09e-05	46.6	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1XEX5@135618|Methylococcales	135618|Methylococcales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_3546_1	498211.CJA_2520	5.46e-43	160.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k59_50856_2	1121374.KB891585_gene1834	2.88e-36	129.0	COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_91585_1	1265505.ATUG01000002_gene2122	2.92e-112	330.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WKAY@28221|Deltaproteobacteria,2MMEB@213118|Desulfobacterales	28221|Deltaproteobacteria	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,TrkA_C
k59_206845_1	313596.RB2501_09220	7.7e-57	194.0	COG3975@1|root,COG3975@2|Bacteria,4NI7I@976|Bacteroidetes,1HYPY@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_77913_1	1165841.SULAR_06918	2.77e-62	199.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2YMK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_77913_2	1165841.SULAR_06928	3.77e-19	80.5	COG1399@1|root,COG1399@2|Bacteria,1Q1I8@1224|Proteobacteria,42TRP@68525|delta/epsilon subdivisions,2YQ23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_43800_1	323261.Noc_2650	4.1e-15	75.9	2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,1WZCE@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,DUF4124
k59_43800_2	2340.JV46_17570	4.86e-18	84.7	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1J4NI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	glnL	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_105164_1	338969.Rfer_4083	4.8e-28	122.0	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,2VZZU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98518_1	65497.JODV01000002_gene4148	1.87e-11	70.5	COG1404@1|root,COG1404@2|Bacteria,2IEGJ@201174|Actinobacteria,4DXZF@85010|Pseudonocardiales	201174|Actinobacteria	O	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,Malectin,Peptidase_S8
k59_118933_1	1165841.SULAR_01110	2.37e-76	232.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_118933_2	1165841.SULAR_01105	1.47e-143	408.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_105169_1	1382359.JIAL01000001_gene2922	3.68e-98	319.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_179324_1	1268239.PALB_18690	5.67e-41	135.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S99Z@1236|Gammaproteobacteria,2Q2VT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	yoeB	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k59_179324_2	493475.GARC_0010	5.22e-39	131.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,1S9S2@1236|Gammaproteobacteria,467AI@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k59_145837_1	1165841.SULAR_08472	9.96e-15	72.8	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42ZC0@68525|delta/epsilon subdivisions,2YR4G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_145837_2	1165841.SULAR_08477	5.74e-78	234.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2YNW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_132272_1	1165841.SULAR_03782	2.66e-100	317.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_200157_1	272621.LBA0932	1.69e-27	116.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
k59_91599_1	1121355.KB903379_gene760	2.89e-05	45.4	COG2510@1|root,COG2510@2|Bacteria,2HW2B@201174|Actinobacteria,22Q8K@1653|Corynebacteriaceae	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
k59_57604_1	679935.Alfi_1238	1.17e-40	153.0	COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,2FMEX@200643|Bacteroidia,22U31@171550|Rikenellaceae	976|Bacteroidetes	G	glycogen debranching enzyme, archaeal type	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
k59_125415_1	1385515.N791_13150	3.83e-10	65.1	COG3637@1|root,COG3637@2|Bacteria,1N7AR@1224|Proteobacteria,1SHEZ@1236|Gammaproteobacteria,1X5E1@135614|Xanthomonadales	135614|Xanthomonadales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_172871_1	1283076.M1I7U4_9CAUD	1.25e-93	296.0	4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses  no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage T4-like capsid assembly protein (Gp20)	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_132274_1	2340.JV46_18560	3.24e-14	69.7	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1J762@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_132274_2	1249627.D779_2258	2.14e-99	295.0	COG0412@1|root,COG0412@2|Bacteria,1RCWF@1224|Proteobacteria,1RY38@1236|Gammaproteobacteria,1WX5X@135613|Chromatiales	135613|Chromatiales	Q	PFAM Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
k59_105180_1	713586.KB900536_gene463	1.54e-58	183.0	COG3791@1|root,COG3791@2|Bacteria,1PY7G@1224|Proteobacteria,1SXYP@1236|Gammaproteobacteria,1X1WI@135613|Chromatiales	135613|Chromatiales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_105180_2	314287.GB2207_07018	4.08e-17	75.5	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1J5ZB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_145843_1	1179778.PMM47T1_13183	4.74e-67	213.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_206866_1	313612.L8106_08996	5.92e-05	50.8	COG2199@1|root,COG3706@2|Bacteria,1G2A0@1117|Cyanobacteria,1H8JI@1150|Oscillatoriales	1117|Cyanobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_8,Response_reg
k59_50873_1	1165841.SULAR_03757	1.95e-27	109.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_50873_2	1165841.SULAR_03762	3.3e-81	254.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_16975_1	867900.Celly_0836	7.16e-120	351.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,1HYVR@117743|Flavobacteriia,1F8UM@104264|Cellulophaga	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_105181_1	156578.ATW7_14281	1.26e-38	149.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_43824_2	1137799.GZ78_28925	2.44e-69	212.0	COG1943@1|root,COG1943@2|Bacteria,1RI1H@1224|Proteobacteria,1T1BV@1236|Gammaproteobacteria,1XQ50@135619|Oceanospirillales	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_3553_1	1165841.SULAR_02933	1.09e-09	57.8	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	hydC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_3553_2	1165841.SULAR_02938	2.77e-153	445.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hydB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_30693_1	1121405.dsmv_1569	3.96e-94	291.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MHTP@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_3555_1	2340.JV46_23660	3.52e-52	185.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1J4BX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_186395_1	313596.RB2501_08405	1.51e-75	231.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_145856_1	1121447.JONL01000007_gene1312	2e-76	256.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,43EBY@68525|delta/epsilon subdivisions,2X7W0@28221|Deltaproteobacteria,2MHDJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_64398_1	676032.FN3523_0601	5.53e-09	62.0	COG2820@1|root,COG2820@2|Bacteria,1P0EC@1224|Proteobacteria,1RN3N@1236|Gammaproteobacteria,461SN@72273|Thiotrichales	72273|Thiotrichales	F	Phosphorylase superfamily	-	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_43836_1	1223410.KN050846_gene134	3.24e-18	79.0	COG2963@1|root,COG2963@2|Bacteria,4NQ8V@976|Bacteroidetes,1I3MZ@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_43836_2	1048983.EL17_09900	5.14e-40	142.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,47P91@768503|Cytophagia	976|Bacteroidetes	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_16991_1	631362.Thi970DRAFT_01055	1.73e-70	238.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
k59_193235_1	1165841.SULAR_02653	1.51e-105	320.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_98544_1	1121904.ARBP01000011_gene1465	1.99e-148	449.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_105199_2	1165841.SULAR_06878	1.29e-59	191.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_146378_2	314285.KT71_03162	9.97e-18	85.5	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_159829_1	948106.AWZT01000071_gene1342	8.79e-41	141.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K8UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	Transposase_20
k59_71604_1	314278.NB231_00200	4.83e-32	126.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1WYS8@135613|Chromatiales	135613|Chromatiales	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,HAMP,HEAT_2,Pkinase,sCache_3_2
k59_200529_1	1165841.SULAR_08527	4.88e-140	400.0	COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,42VE6@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_37486_1	96561.Dole_3250	5.05e-93	285.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_92126_1	472759.Nhal_3717	1.25e-98	303.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales	135613|Chromatiales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_119400_1	1123393.KB891318_gene2177	3.54e-36	133.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2VH8U@28216|Betaproteobacteria,1KSBU@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
k59_71607_1	1165841.SULAR_08724	1.95e-28	110.0	COG1807@1|root,COG1807@2|Bacteria,1Q901@1224|Proteobacteria,42MGX@68525|delta/epsilon subdivisions,2YNER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_71607_2	1172190.M947_03965	9.38e-37	134.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42YXJ@68525|delta/epsilon subdivisions,2YR3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP citrate lyase citrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2,Citrate_bind
k59_51342_1	1165841.SULAR_09389	4.88e-51	178.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2YRID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13,SPOR
k59_105741_1	1165841.SULAR_05628	2.26e-42	144.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,42MBG@68525|delta/epsilon subdivisions,2YMHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	pfs	-	3.2.2.30,3.2.2.9	ko:K18284	ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R10668	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_105741_2	1165841.SULAR_05633	1.49e-60	194.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2YMWK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_213897_1	983545.Glaag_2253	1.28e-67	229.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,464A0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_125937_1	1123053.AUDG01000018_gene3020	1.11e-53	189.0	COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1S13U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_115506_1	522306.CAP2UW1_0207	1.17e-12	70.1	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
k59_176489_1	1121116.KB894766_gene437	4.72e-19	88.2	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,4ADS0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin
k59_149364_1	1122179.KB890497_gene2751	1.96e-13	78.2	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes,1IYDP@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_128974_1	640081.Dsui_0900	2.26e-41	144.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,2KVN6@206389|Rhodocyclales	206389|Rhodocyclales	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_128974_2	1297617.JPJD01000032_gene2068	0.000295	44.7	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,268BW@186813|unclassified Clostridiales	186801|Clostridia	M	Beta-lactamase enzyme family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_40943_1	1541065.JRFE01000073_gene3320	6.61e-68	221.0	COG3464@1|root,COG3464@2|Bacteria,1G42D@1117|Cyanobacteria,3VMW4@52604|Pleurocapsales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_101986_1	391587.KAOT1_22641	3.26e-08	60.1	COG1361@1|root,COG1361@2|Bacteria,4NMB8@976|Bacteroidetes,1HYNW@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,SdrD_B,SprB
k59_7043_1	483219.LILAB_30110	1.6e-71	250.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,TauD,Thioesterase,ketoacyl-synt
k59_210412_1	387093.SUN_1342	2.11e-31	125.0	COG1289@1|root,COG1289@2|Bacteria,1PSN0@1224|Proteobacteria,42WM7@68525|delta/epsilon subdivisions,2YSKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_210412_2	338966.Ppro_2218	1.9e-05	48.5	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MKA@68525|delta/epsilon subdivisions,2WNAP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_20665_1	62928.azo3379	2.52e-15	76.6	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria,2KVMB@206389|Rhodocyclales	206389|Rhodocyclales	S	Beta-lactamase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_135799_1	717231.Flexsi_0074	1.85e-37	140.0	COG0341@1|root,COG0341@2|Bacteria,2GEP5@200930|Deferribacteres	200930|Deferribacteres	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_286_1	1168034.FH5T_07960	9.38e-57	192.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,2FUCA@200643|Bacteroidia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_162970_1	1265313.HRUBRA_01434	3.9e-92	292.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,1J5G2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338,ko:K08675	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03029	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_61308_1	675635.Psed_1304	5.61e-22	100.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpV	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K12954,ko:K12956,ko:K17686,ko:K21887	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_108704_1	2340.JV46_25730	4.38e-72	224.0	COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_156201_1	1165841.SULAR_06738	3.85e-106	325.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42Z4X@68525|delta/epsilon subdivisions,2YRD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_54480_1	1121939.L861_01450	9.56e-48	164.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,1XP0V@135619|Oceanospirillales	135619|Oceanospirillales	P	Eukaryotic-type carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_210427_1	1165841.SULAR_01270	6.02e-62	212.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_149376_1	1122169.AREN01000008_gene868	4.11e-19	86.7	COG3882@1|root,COG3882@2|Bacteria,1PNPC@1224|Proteobacteria,1RSDT@1236|Gammaproteobacteria,1JF5K@118969|Legionellales	118969|Legionellales	Q	enzyme involved in methoxymalonyl-ACP biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128986_1	261292.Nit79A3_3398	1.24e-22	102.0	2CGCV@1|root,31JER@2|Bacteria,1RJJ8@1224|Proteobacteria	1224|Proteobacteria	S	Thrombospondin C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TSP_C,VPEP
k59_135808_1	595494.Tola_0300	1.49e-99	306.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1Y3VC@135624|Aeromonadales	135624|Aeromonadales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k59_142620_1	313596.RB2501_06780	9.02e-98	293.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,1HY6H@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
k59_122294_1	523791.Kkor_0859	1.85e-68	220.0	COG0106@1|root,COG0139@1|root,COG0140@1|root,COG0106@2|Bacteria,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XK33@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,PRA-CH,PRA-PH
k59_40957_1	1249997.JHZW01000002_gene851	3.24e-76	248.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia,2PGX1@252356|Maribacter	976|Bacteroidetes	P	Phosphate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_20685_1	1121875.KB907547_gene3019	6e-83	259.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_20685_2	313595.P700755_002263	3.9e-14	72.4	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia,4C30C@83612|Psychroflexus	976|Bacteroidetes	S	Domain of unknown function (DUF4131)	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
k59_54486_1	1165841.SULAR_09579	4.64e-149	422.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,42MHJ@68525|delta/epsilon subdivisions,2YMM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	dinuclear metal center protein, YbgI	-	-	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
k59_54486_2	387093.SUN_0361	1.13e-07	54.7	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
k59_47722_1	305700.B447_18558	4.95e-78	261.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_190118_1	96561.Dole_0802	7.52e-40	133.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42UFU@68525|delta/epsilon subdivisions,2WR59@28221|Deltaproteobacteria,2MKI0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_190118_2	1121405.dsmv_1711	5.88e-14	69.3	COG0711@1|root,COG0711@2|Bacteria,1NANU@1224|Proteobacteria,42VCJ@68525|delta/epsilon subdivisions,2WRGZ@28221|Deltaproteobacteria,2MM1Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_108709_1	63737.Npun_F1213	1.49e-47	172.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HK2M@1161|Nostocales	1117|Cyanobacteria	S	C-terminal of Roc, COR, domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_1,LRR_4,LRR_8,LRR_9,Roc
k59_102011_1	1454004.AW11_01184	1.94e-36	142.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_115530_1	1121405.dsmv_2382	2.46e-17	86.3	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2MIC5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_203625_1	314285.KT71_12790	2.26e-86	282.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria,1J9EJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_54495_1	2340.JV46_27550	3.86e-66	209.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_54495_2	298386.PBPRA2812	3.13e-19	83.6	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,1XU34@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_122306_1	713587.THITH_17380	6.83e-39	136.0	COG3439@1|root,COG3439@2|Bacteria,1RA8I@1224|Proteobacteria,1S34D@1236|Gammaproteobacteria,1WXZJ@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_203630_1	616991.JPOO01000003_gene1808	3.56e-39	134.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1I1XM@117743|Flavobacteriia,23FWW@178469|Arenibacter	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_203630_2	313596.RB2501_08970	8.17e-42	146.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,1HZ4X@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_88443_2	714943.Mucpa_3155	1.29e-76	239.0	COG1028@1|root,COG1028@2|Bacteria,4P0BT@976|Bacteroidetes,1IWK3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_88443_3	1500894.JQNN01000001_gene737	2.18e-46	160.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,47279@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF480	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k59_13865_1	502025.Hoch_2304	2.78e-34	137.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2YU9U@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k59_95167_1	395493.BegalDRAFT_1285	2e-48	176.0	COG1672@1|root,COG1672@2|Bacteria,1N54W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162998_1	1165841.SULAR_10364	4.2e-164	499.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_68107_2	1165841.SULAR_01803	1.8e-75	232.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2YP5A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_48156_1	1209072.ALBT01000051_gene534	1.84e-27	111.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1FFUX@10|Cellvibrio	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	gacA	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_163408_1	59689.scaffold_201066.1	1.79e-40	148.0	COG0055@1|root,COG0355@1|root,KOG1350@2759|Eukaryota,KOG1758@2759|Eukaryota,37K5M@33090|Viridiplantae,3GCIP@35493|Streptophyta,3I24X@3699|Brassicales	35493|Streptophyta	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpB	-	3.6.3.14	ko:K02112,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N,ATP-synt_ab,ATP-synt_ab_N
k59_170129_1	765910.MARPU_12605	5.64e-92	295.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_21115_1	493475.GARC_3963	1.06e-24	100.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,464XT@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_21115_2	1122236.KB905141_gene905	1.61e-26	102.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,2KM99@206350|Nitrosomonadales	206350|Nitrosomonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_75252_1	472759.Nhal_2930	6.77e-39	136.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,1SZ4J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_75252_2	211165.AJLN01000135_gene5748	2.95e-21	90.1	COG3415@1|root,COG3415@2|Bacteria,1GKFF@1117|Cyanobacteria,1JM31@1189|Stigonemataceae	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_27867_1	261292.Nit79A3_3384	2.83e-44	159.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,371VC@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D2
k59_7416_1	1214101.BN159_3168	1.6e-23	101.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K12239	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,Condensation,Nitroreductase,PP-binding
k59_210886_1	870187.Thini_1609	1.15e-64	209.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_210886_2	870187.Thini_3937	1.98e-94	287.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_21125_1	765913.ThidrDRAFT_2898	8.01e-41	145.0	2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,1RZVK@1236|Gammaproteobacteria,1WWI9@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156662_1	2340.JV46_15750	6.43e-40	142.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1J5BU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_156662_2	443152.MDG893_12675	4.87e-21	92.4	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,464DY@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_129461_1	56780.SYN_03213	1.62e-96	292.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MR3T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_14310_1	1168034.FH5T_04270	4.19e-97	291.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,2FXM7@200643|Bacteroidia	976|Bacteroidetes	F	AIR synthase related protein, C-terminal domain	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
k59_68540_1	1165841.SULAR_08849	1.4e-162	462.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2YMEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k59_68540_2	1165841.SULAR_08854	8.42e-55	178.0	COG2204@1|root,COG2204@2|Bacteria,1QUIV@1224|Proteobacteria,42M4N@68525|delta/epsilon subdivisions,2YMIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_82095_1	118168.MC7420_435	0.000811	41.2	2C5EZ@1|root,32YI6@2|Bacteria,1G9I0@1117|Cyanobacteria,1HD0H@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82095_2	1125699.HMPREF9194_01606	2.07e-18	81.3	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_82095_3	631362.Thi970DRAFT_03240	1.93e-20	84.3	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
k59_170146_1	1499967.BAYZ01000137_gene98	4.39e-33	136.0	COG1409@1|root,COG2304@1|root,COG4677@1|root,COG1409@2|Bacteria,COG2304@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	rapB1	-	3.2.1.18,4.2.2.2	ko:K01186,ko:K01728,ko:K07004,ko:K12548	ko00040,ko00511,ko00600,ko02024,ko04142,map00040,map00511,map00600,map02024,map04142	-	R02361,R04018,R06240	RC00028,RC00049,RC00077,RC00705	ko00000,ko00001,ko01000,ko02042	-	GH33	-	Beta_helix,Laminin_G_3
k59_136261_1	1165841.SULAR_05788	3.32e-43	145.0	COG0476@1|root,COG0476@2|Bacteria,1P1FY@1224|Proteobacteria,42PK6@68525|delta/epsilon subdivisions,2YNCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_136261_2	1165841.SULAR_05783	1.67e-44	145.0	2B3E9@1|root,31W34@2|Bacteria,1MZ95@1224|Proteobacteria,42U85@68525|delta/epsilon subdivisions,2YQ41@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14316_1	1121007.AUML01000011_gene3519	2.37e-07	51.6	COG0491@1|root,COG0491@2|Bacteria,4NJZR@976|Bacteroidetes,1HZBW@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_14316_2	313596.RB2501_05920	7.51e-92	273.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1HWTU@117743|Flavobacteriia	976|Bacteroidetes	O	Part of SUF system involved in inserting iron-sulfur clusters into proteins	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_143040_1	1168034.FH5T_07830	1.36e-14	73.2	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,2FXCC@200643|Bacteroidia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_143040_2	1168034.FH5T_07825	8.83e-48	157.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k59_116006_1	2340.JV46_02720	5.89e-52	184.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	2.7.11.1	ko:K03546,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko03400	-	-	-	AAA_23,Pkinase,SMC_N
k59_174241_1	1347393.HG726021_gene295	5.39e-38	141.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_5,Abhydrolase_6,Hydrolase_4
k59_112864_1	1168034.FH5T_16970	2.71e-56	178.0	COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
k59_112864_2	1168034.FH5T_16965	1.91e-08	55.1	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_112865_1	1453501.JELR01000002_gene529	3.61e-42	152.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_112865_2	118173.KB235914_gene1128	8.73e-32	118.0	COG0431@1|root,COG0431@2|Bacteria,1G22E@1117|Cyanobacteria,1H8TA@1150|Oscillatoriales	1117|Cyanobacteria	S	Nadph-dependent fmn reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
k59_65933_1	28229.ND2E_2258	1.53e-16	80.1	COG0318@1|root,COG0318@2|Bacteria,1R5I6@1224|Proteobacteria,1RNFC@1236|Gammaproteobacteria,2Q7K1@267889|Colwelliaceae	1236|Gammaproteobacteria	IQ	AMP-binding enzyme	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
k59_45477_1	870187.Thini_2563	7.36e-76	237.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_72677_1	387093.SUN_1107	4.96e-97	310.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_133951_1	1121875.KB907552_gene276	2.28e-111	323.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_208343_1	1168034.FH5T_03850	9.77e-59	203.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_45479_1	395493.BegalDRAFT_2894	1.02e-69	216.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,460IU@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_45479_2	243233.MCA1065	1.34e-44	148.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1XF9Z@135618|Methylococcales	135618|Methylococcales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_140284_1	519989.ECTPHS_10696	7.66e-13	68.2	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_140284_2	518766.Rmar_1719	4.06e-05	47.4	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1FJBN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_72679_1	28229.ND2E_3471	3.45e-60	199.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,2Q7V3@267889|Colwelliaceae	1236|Gammaproteobacteria	U	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_133953_2	314230.DSM3645_21122	8.91e-77	233.0	2EPE8@1|root,33H0U@2|Bacteria,2J3C3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201418_1	10224.XP_006826129.1	1.01e-86	289.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k59_99898_1	248742.XP_005646805.1	8.65e-33	124.0	COG3186@1|root,KOG3820@2759|Eukaryota,37IBP@33090|Viridiplantae,34K7X@3041|Chlorophyta	3041|Chlorophyta	E	Biopterin-dependent aromatic amino acid hydroxylase	-	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
k59_187824_1	1500893.JQNB01000001_gene1717	1.74e-59	189.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1X304@135614|Xanthomonadales	135614|Xanthomonadales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_187824_2	998674.ATTE01000001_gene4288	8.76e-34	119.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,460I6@72273|Thiotrichales	72273|Thiotrichales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_112881_1	991905.SL003B_1339	3.63e-26	107.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,4BPKS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_112881_2	342610.Patl_3526	3.93e-06	48.5	COG3116@1|root,COG3116@2|Bacteria,1N9MH@1224|Proteobacteria,1SC7P@1236|Gammaproteobacteria,2Q2TU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
k59_167454_1	1165841.SULAR_03342	1.78e-50	172.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_167454_2	1165841.SULAR_03347	3.89e-54	175.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_38309_1	765869.BDW_10825	1.44e-18	84.7	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2MUEX@213481|Bdellovibrionales,2WQRF@28221|Deltaproteobacteria	213481|Bdellovibrionales	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_65946_1	2340.JV46_11930	3.52e-70	223.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1J4U9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	antiporter	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_140290_1	1165841.SULAR_08512	1.6e-42	143.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928	GTP_cyclohydroI
k59_140290_2	1165841.SULAR_08507	1.22e-58	191.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_167459_1	1127673.GLIP_1552	8.77e-41	153.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,468K9@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C
k59_133964_1	395493.BegalDRAFT_3539	2.26e-94	293.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,461YB@72273|Thiotrichales	72273|Thiotrichales	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
k59_25103_1	1121920.AUAU01000005_gene1008	5.06e-106	330.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_59139_1	268748.Q58N56_BPPRP	9.68e-63	199.0	4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses  no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120309_1	696747.NIES39_Q00060	6.13e-05	46.6	COG3243@1|root,COG3243@2|Bacteria,1G33I@1117|Cyanobacteria,1H852@1150|Oscillatoriales	1117|Cyanobacteria	I	Protein of unknown function (DUF3141)	phaC	GO:0008150,GO:0008152,GO:0009058,GO:0042618,GO:0042619,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	iJN678.phbC	Abhydrolase_1
k59_120309_2	2340.JV46_12450	4.06e-20	93.2	28KIX@1|root,2Z9Y0@2|Bacteria,1R427@1224|Proteobacteria,1RRGI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit	phaE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
k59_18544_1	2340.JV46_03510	7.58e-89	274.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J4EJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740	PK,PK_C
k59_113274_1	1165841.SULAR_06578	1.13e-106	326.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_167945_1	66377.JOBH01000004_gene3834	1.31e-41	157.0	COG0318@1|root,COG1028@1|root,COG0318@2|Bacteria,COG1028@2|Bacteria,2I2RH@201174|Actinobacteria	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,KR,PP-binding
k59_52627_1	1453503.AU05_21150	1.22e-18	87.4	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_52627_2	2340.JV46_26350	2.24e-91	278.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1J4MT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_201933_1	335283.Neut_1777	1.55e-43	152.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,3720J@32003|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_167946_1	1121930.AQXG01000007_gene478	1.36e-09	58.5	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1IR43@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_45967_1	1165841.SULAR_05593	3.26e-108	318.0	COG2177@1|root,COG2177@2|Bacteria,1R85B@1224|Proteobacteria,42PX3@68525|delta/epsilon subdivisions,2YQ4H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
k59_5589_1	1122138.AQUZ01000041_gene7242	1.02e-20	90.5	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4DUY3@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_32403_1	997830.HMPREF1124_0564	4.02e-12	70.9	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,43G1Y@68892|Streptococcus infantis	91061|Bacilli	S	Transporter associated domain	hlyX	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_174701_1	1313304.CALK_0608	2.78e-53	191.0	COG0475@1|root,COG1762@1|root,COG0475@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	kefB	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	Na_H_Exchanger,PTS_EIIA_2
k59_107267_1	1095769.CAHF01000022_gene432	3.96e-96	323.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_167955_1	1165841.SULAR_01160	1.18e-94	286.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,42PT0@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_134306_1	1232437.KL662014_gene1301	1.64e-23	103.0	COG2414@1|root,COG2414@2|Bacteria,1R9KF@1224|Proteobacteria,42PQB@68525|delta/epsilon subdivisions,2WKS3@28221|Deltaproteobacteria,2MPW2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_181346_1	1046625.AFQY01000003_gene2479	1.56e-27	109.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,1RT3H@1236|Gammaproteobacteria,3NJ71@468|Moraxellaceae	1236|Gammaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_32411_1	377629.TERTU_2295	8.16e-56	192.0	COG1032@1|root,COG1032@2|Bacteria,1PFIF@1224|Proteobacteria,1SWGW@1236|Gammaproteobacteria,2PQ5T@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140690_1	1216967.L100_13879	1.15e-126	369.0	COG3677@1|root,COG3677@2|Bacteria,4NPDE@976|Bacteroidetes,1I5ER@117743|Flavobacteriia	976|Bacteroidetes	L	Protein involved in DNA binding, transposase activity and transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,Transposase_mut
k59_19055_2	1288298.rosmuc_03888	8.25e-39	143.0	COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,2TSQQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Conjugal transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,MobA_MobL,Relaxase,Viral_helicase1
k59_208708_1	740709.A10D4_05762	2.63e-07	50.4	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,2QG4K@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iYL1228.KPN_03664	Biotin_lipoyl
k59_208708_2	999611.KI421504_gene3162	9.73e-106	320.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,27ZNS@191028|Leisingera	28211|Alphaproteobacteria	I	ATP-grasp domain	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_11923_1	1235788.C802_01133	1.11e-46	168.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,2FN3P@200643|Bacteroidia,4AMTA@815|Bacteroidaceae	976|Bacteroidetes	D	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
k59_215112_1	1123393.KB891326_gene36	1.51e-10	62.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2VR0S@28216|Betaproteobacteria,1KSTC@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_66450_1	118168.MC7420_4838	4.67e-89	270.0	COG2084@1|root,COG2084@2|Bacteria,1G3A6@1117|Cyanobacteria,1HAFH@1150|Oscillatoriales	1117|Cyanobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
k59_11925_1	402777.KB235898_gene5119	1.79e-15	77.0	COG0683@1|root,COG0683@2|Bacteria,1G1WJ@1117|Cyanobacteria,1H79U@1150|Oscillatoriales	1117|Cyanobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_25483_1	1101190.ARWB01000001_gene744	2.18e-79	249.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2TRA6@28211|Alphaproteobacteria,370BJ@31993|Methylocystaceae	28211|Alphaproteobacteria	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_25483_2	1392489.JPOL01000002_gene2700	2.35e-06	48.5	COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,1HZTF@117743|Flavobacteriia,2XJF6@283735|Leeuwenhoekiella	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.183,3.2.1.184	ko:K08068,ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
k59_134329_1	1049564.TevJSym_ai00870	1.75e-48	174.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1J4VK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_73020_1	1163407.UU7_14800	1.25e-42	157.0	2EHP3@1|root,33BEW@2|Bacteria,1RHA6@1224|Proteobacteria,1SJY9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215125_1	1267533.KB906741_gene430	2.07e-28	115.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria,2JIDH@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_215125_2	107636.JQNK01000009_gene2317	2.23e-10	62.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,36YH3@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	tdcB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_195194_1	1384056.N787_11090	4.96e-18	82.4	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1X3S4@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_5619_1	1121104.AQXH01000001_gene1400	4.37e-71	231.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_107294_1	391615.ABSJ01000041_gene2	1.1e-14	73.9	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1J587@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
k59_107294_2	87626.PTD2_11474	2.15e-61	209.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,2PZGY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_185631_1	566466.NOR53_3441	6.84e-85	263.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1J7W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_138158_1	313596.RB2501_11452	7.99e-188	533.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1HX65@117743|Flavobacteriia	976|Bacteroidetes	J	TRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_63779_1	1168034.FH5T_05370	1.96e-22	96.3	COG4773@1|root,COG4773@2|Bacteria,4PM17@976|Bacteroidetes,2G187@200643|Bacteroidia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_178762_1	1168034.FH5T_16965	8.16e-74	229.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36425_1	1165841.SULAR_02543	2.81e-119	351.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_199455_1	283699.D172_2441	2.31e-63	206.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,2PZIJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0382	AIRS,AIRS_C
k59_111119_1	1499967.BAYZ01000090_gene4959	1.26e-73	243.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2NNT2@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00162,ko:K00167,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_97885_1	504728.K649_14655	8.21e-35	136.0	COG0557@1|root,COG0557@2|Bacteria,1WI1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_IclR,OB_RNB,RNB,S1
k59_145059_1	595537.Varpa_3209	0.000407	48.9	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,2VHPF@28216|Betaproteobacteria,4AB26@80864|Comamonadaceae	28216|Betaproteobacteria	M	Bacterial cellulose synthase subunit	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB
k59_172202_1	767817.Desgi_0498	2.23e-13	75.5	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,260ZM@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_29988_1	1165841.SULAR_02953	7.61e-66	216.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_212815_1	2340.JV46_26130	3.4e-26	105.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1SJJV@1236|Gammaproteobacteria,1J77S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	-	-	-	-	-	-	-	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
k59_212815_2	305700.B447_21227	5.25e-34	123.0	COG0394@1|root,COG0394@2|Bacteria,1N0DZ@1224|Proteobacteria,2VUYF@28216|Betaproteobacteria,2KZCG@206389|Rhodocyclales	206389|Rhodocyclales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_212815_3	1134474.O59_000457	7.87e-35	128.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1FFT8@10|Cellvibrio	1236|Gammaproteobacteria	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_124751_1	1123355.JHYO01000030_gene365	5.57e-39	149.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,37001@31993|Methylocystaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,dCache_1
k59_43298_1	1177181.T9A_00237	2.14e-19	92.8	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XN31@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_16322_1	522306.CAP2UW1_3815	1.62e-18	87.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,1KQZ0@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_16322_2	754477.Q7C_2336	4.65e-12	66.2	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,4610C@72273|Thiotrichales	72273|Thiotrichales	N	Belongs to the bacterial flagellin family	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_70473_1	1449350.OCH239_03905	2.96e-26	105.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_70473_2	459495.SPLC1_S040120	7.8e-07	54.7	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G06Q@1117|Cyanobacteria,1HA2E@1150|Oscillatoriales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_Tnp_IS630
k59_206168_1	579405.Dd703_1931	1.94e-07	52.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,2JCZB@204037|Dickeya	1236|Gammaproteobacteria	S	SMART phosphoesterase PHP domain protein	trpH	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k59_124758_1	1392490.JHZX01000001_gene2677	1.58e-21	96.3	28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,1HX78@117743|Flavobacteriia	976|Bacteroidetes	S	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
k59_118169_1	1165841.SULAR_01823	4.13e-123	356.0	2CEAP@1|root,3322D@2|Bacteria,1N7SG@1224|Proteobacteria,42WE8@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63797_1	1249627.D779_1971	3.34e-126	371.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_70481_1	1165841.SULAR_03767	1.29e-172	487.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_151859_1	395965.Msil_2844	2.83e-34	134.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2U0ZY@28211|Alphaproteobacteria,3NAVP@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_212829_2	1231190.NA8A_09449	1.06e-10	63.5	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,43GXC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	short-chain	ptr1	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_178775_1	420324.KI912086_gene7296	8.3e-07	55.1	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_2,TPR_8
k59_104481_2	326427.Cagg_1493	1.2e-14	73.6	COG3501@1|root,COG3501@2|Bacteria,2G6XN@200795|Chloroflexi	200795|Chloroflexi	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124767_2	1049564.TevJSym_av00170	5.53e-82	256.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1J547@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iEC042_1314.EC042_2616	tRNA-synt_1c
k59_2893_1	1168034.FH5T_12935	4.2e-102	298.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_151860_1	2340.JV46_23320	6.71e-153	437.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1J6TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_4539,iSBO_1134.SBO_4033,iSbBS512_1146.SbBS512_E4507	HTS
k59_30015_1	1165841.SULAR_00280	4.13e-136	397.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_212834_1	1165841.SULAR_02953	9.73e-135	398.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_97912_1	443143.GM18_3946	2.01e-17	84.3	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,43W1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_97912_2	411154.GFO_0160	1.3e-27	111.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_50397_1	1250232.JQNJ01000001_gene1346	3.44e-108	330.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia	976|Bacteroidetes	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_77361_1	631362.Thi970DRAFT_00715	3.12e-47	169.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_84228_1	1210884.HG799468_gene13829	3.41e-25	108.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
k59_23084_1	765912.Thimo_1274	1.13e-42	155.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1WX1Q@135613|Chromatiales	135613|Chromatiales	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_97922_1	1540221.JQNI01000002_gene1453	3.86e-06	51.6	COG2770@1|root,COG2770@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,dCache_1
k59_77364_1	1165841.SULAR_08232	4.28e-117	346.0	COG3203@1|root,COG3203@2|Bacteria,1R1K3@1224|Proteobacteria,43DCJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_97923_1	1056820.KB900651_gene3146	8.55e-62	197.0	COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,1RSHR@1236|Gammaproteobacteria,2PPJQ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_97923_2	765911.Thivi_2767	4.11e-11	64.3	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WWA8@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_212848_1	315456.RF_0482	3.59e-05	48.1	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2TT7B@28211|Alphaproteobacteria,47FGU@766|Rickettsiales	766|Rickettsiales	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k59_84235_1	1165841.SULAR_04532	1.68e-99	315.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_30040_1	1167006.UWK_01043	1.06e-93	300.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	bamE	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2
k59_206200_1	224911.27348496	3.81e-16	82.8	COG0402@1|root,COG0402@2|Bacteria,1R9S5@1224|Proteobacteria,2U10N@28211|Alphaproteobacteria,3JU9Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_97926_1	379731.PST_3678	8.57e-126	372.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1YZXX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_16333_1	4155.Migut.F01470.1.p	8.91e-217	598.0	COG1007@1|root,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,44UT6@71274|asterids	35493|Streptophyta	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K05573	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M
k59_16333_2	4572.TRIUR3_00337-P1	2.4e-100	291.0	COG0049@1|root,KOG3291@2759|Eukaryota,37YX8@33090|Viridiplantae,3GNS6@35493|Streptophyta,3KTYP@4447|Liliopsida,3IAPX@38820|Poales	35493|Streptophyta	J	ribosomal protein S7	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S7
k59_56950_1	1178537.BA1_02985	5.41e-41	154.0	COG0367@1|root,COG0367@2|Bacteria,1VT9B@1239|Firmicutes,4HUM7@91061|Bacilli,1ZMNE@1386|Bacillus	91061|Bacilli	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_43323_1	132113.XP_003494838.1	2.02e-26	108.0	COG0519@1|root,KOG1622@2759|Eukaryota,38DHS@33154|Opisthokonta,3BDTV@33208|Metazoa,3CW4N@33213|Bilateria,41TJK@6656|Arthropoda,3SJCG@50557|Insecta,46GX7@7399|Hymenoptera	33208|Metazoa	F	GMP synthase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_43323_2	1123401.JHYQ01000003_gene2105	3.84e-67	217.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,45ZZA@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_50411_1	1165841.SULAR_08075	1.38e-37	134.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2YMZH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_3397_1	2340.JV46_06620	3.29e-86	266.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1J9BP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_3397_2	2340.JV46_06610	5.41e-83	264.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_186206_2	1121091.AUMP01000003_gene2690	5.65e-24	98.2	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli	91061|Bacilli	K	Histone acetyltransferase HPA2 and related acetyltransferases	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_23518_1	985255.APHJ01000028_gene985	2.54e-95	286.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia,2P6KA@244698|Gillisia	976|Bacteroidetes	S	ATPases associated with a variety of cellular activities	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_85676_1	1449355.JQNR01000005_gene4307	1.16e-16	80.1	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_85676_2	1168034.FH5T_01025	2.08e-39	143.0	COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes	976|Bacteroidetes	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_N
k59_112320_1	998674.ATTE01000001_gene670	1.79e-20	91.3	COG3409@1|root,COG3409@2|Bacteria,1N3E4@1224|Proteobacteria,1RZ2A@1236|Gammaproteobacteria,4624D@72273|Thiotrichales	72273|Thiotrichales	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
k59_214068_1	1323663.AROI01000020_gene717	1.16e-31	115.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S4NE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Type IV pilus response regulator PilH	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_58404_1	1168034.FH5T_18215	2.73e-81	243.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,2FSTU@200643|Bacteroidia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_10796_1	765914.ThisiDRAFT_2031	9.98e-101	305.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_160134_1	1449335.JQLG01000004_gene2101	3.17e-21	92.4	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27FS6@186828|Carnobacteriaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_31354_1	395019.Bmul_0889	6.29e-09	59.7	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,2VHS9@28216|Betaproteobacteria,1KFDI@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_71862_1	926549.KI421517_gene3440	1.49e-54	186.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,47J97@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_153340_1	999141.GME_09626	7.35e-25	105.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1XHE2@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_153340_2	2340.JV46_10890	5.4e-20	86.7	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1J8PV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Phosphoribulokinase / Uridine kinase family	prkB	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_214072_1	1049564.TevJSym_ac00050	1.27e-43	147.0	COG4314@1|root,COG4314@2|Bacteria,1N3G0@1224|Proteobacteria,1SPJU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
k59_214072_2	1049564.TevJSym_ac00060	2.18e-23	96.7	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	abc transporter atp-binding protein	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_85688_1	1168034.FH5T_06720	4.97e-99	308.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,2FMI1@200643|Bacteroidia	976|Bacteroidetes	E	peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009987,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033218,GO:0034641,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
k59_126169_1	1232410.KI421413_gene776	3.77e-30	120.0	COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria,1MWF8@1224|Proteobacteria,42PRD@68525|delta/epsilon subdivisions,2X5MX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_153345_1	880071.Fleli_3106	2.72e-55	195.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
k59_92395_1	1168034.FH5T_04015	9.84e-107	343.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_71870_1	421531.IX38_07895	1.4e-21	93.2	COG5018@1|root,COG5018@2|Bacteria,4NGIP@976|Bacteroidetes,1I10Q@117743|Flavobacteriia,3ZNIX@59732|Chryseobacterium	976|Bacteroidetes	L	DNA polymerase III	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
k59_133150_1	489825.LYNGBM3L_53030	1.67e-92	281.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1G21B@1117|Cyanobacteria,1H7N0@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_112331_1	237368.SCABRO_03591	1.77e-38	145.0	COG0845@1|root,COG0845@2|Bacteria,2IYDV@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_65131_1	655815.ZPR_2875	3.37e-37	142.0	COG4948@1|root,COG4948@2|Bacteria,4PKP3@976|Bacteroidetes,1HZYY@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
k59_106040_1	765914.ThisiDRAFT_1082	3.91e-31	115.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_106040_2	1407650.BAUB01000007_gene1568	9.38e-24	98.2	COG0264@1|root,COG0264@2|Bacteria,1G00T@1117|Cyanobacteria,1GYCT@1129|Synechococcus	1117|Cyanobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_37703_1	360911.EAT1b_2865	6.47e-89	279.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3WDZ8@539002|Bacillales incertae sedis	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_65134_1	316067.Geob_3522	8.75e-34	131.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	baeS	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_58427_1	1165841.SULAR_01215	1.85e-77	241.0	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions,2YR4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_58427_2	1165841.SULAR_09719	5.48e-35	130.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_173471_1	204669.Acid345_1131	8.28e-110	328.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria,2JIRM@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_10814_1	1137799.GZ78_11890	1.86e-18	89.7	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1XKYA@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k59_10814_2	745014.OMB55_00021680	3.25e-10	58.5	COG0810@1|root,COG0810@2|Bacteria,1NI06@1224|Proteobacteria,1SA5F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB4	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_65135_1	1304885.AUEY01000002_gene330	8.95e-55	181.0	COG1418@1|root,COG1418@2|Bacteria,1RGCM@1224|Proteobacteria,42RC5@68525|delta/epsilon subdivisions,2WNBA@28221|Deltaproteobacteria,2MJS4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_194038_1	1165841.SULAR_01698	3.63e-18	82.4	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_194038_2	1165841.SULAR_01693	4.58e-86	256.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2YPJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_194038_3	1165841.SULAR_01688	3.46e-93	280.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_65138_1	1249480.B649_03280	9.84e-48	174.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_99357_1	1042376.AFPK01000063_gene1120	1.19e-57	187.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
k59_99357_2	521674.Plim_2857	5.2e-12	66.2	COG0673@1|root,COG0673@2|Bacteria,2IX6I@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_160164_1	1165841.SULAR_08582	1.09e-98	296.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2YMGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_207668_1	984962.XP_009550215.1	3.43e-11	68.6	KOG0266@1|root,KOG0266@2759|Eukaryota,38E6T@33154|Opisthokonta,3NUUI@4751|Fungi,3UYSJ@5204|Basidiomycota,225U6@155619|Agaricomycetes,3H20J@355688|Agaricomycetes incertae sedis	4751|Fungi	S	WD40 repeat-like protein	-	-	-	ko:K06666	ko04011,ko04111,map04011,map04111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Tup_N,WD40
k59_126184_1	886379.AEWI01000037_gene2924	1.51e-57	188.0	COG3401@1|root,COG3401@2|Bacteria,4NKNR@976|Bacteroidetes,2FX7E@200643|Bacteroidia,3XK7N@558415|Marinilabiliaceae	976|Bacteroidetes	S	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_24520_1	1121104.AQXH01000001_gene1723	1.29e-87	276.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1IPZE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_146693_1	1049564.TevJSym_aa01930	2.21e-83	276.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_166711_1	768670.Calni_0147	9.03e-52	186.0	COG0326@1|root,COG0326@2|Bacteria,2GF3F@200930|Deferribacteres	200930|Deferribacteres	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_44624_1	580332.Slit_1659	8.8e-62	199.0	COG3221@1|root,COG3221@2|Bacteria,1MX7I@1224|Proteobacteria,2VP4Q@28216|Betaproteobacteria,44VB1@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_4367_1	72658.Bostr.12474s0002.1.p	2.83e-52	167.0	COG1005@1|root,KOG4770@2759|Eukaryota,37XCB@33090|Viridiplantae,3GWP4@35493|Streptophyta,3I0BQ@3699|Brassicales	35493|Streptophyta	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K03878	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_92410_1	1260251.SPISAL_06995	9.46e-65	213.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1WVZD@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_119646_1	740709.A10D4_00915	3.68e-31	125.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,2QFST@267893|Idiomarinaceae	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_119646_2	1085623.GNIT_2807	0.000245	43.5	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
k59_24523_2	1040982.AXAL01000015_gene2402	5.45e-07	55.8	2AMF5@1|root,31CAN@2|Bacteria,1P9QS@1224|Proteobacteria,2UYFM@28211|Alphaproteobacteria,43QR1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_99364_1	1519464.HY22_08590	2.98e-62	206.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_58450_1	530564.Psta_1166	6.18e-78	248.0	COG3712@1|root,COG3712@2|Bacteria,2IZ99@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,Laminin_G_3
k59_160178_1	28583.AMAG_01413T0	3.78e-71	230.0	COG0418@1|root,KOG2902@2759|Eukaryota,38HVG@33154|Opisthokonta,3NU7X@4751|Fungi	4751|Fungi	F	dihydroorotase	URA4	GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019856,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YLR420W,iND750.YLR420W	Amidohydro_1,Amidohydro_2
k59_119647_1	1279009.ADICEAN_03078	2.03e-62	214.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47P0R@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
k59_44636_1	1232437.KL662019_gene628	1.23e-64	207.0	COG3385@1|root,COG3385@2|Bacteria,1NUI6@1224|Proteobacteria,42ZJ8@68525|delta/epsilon subdivisions,2WV27@28221|Deltaproteobacteria,2MND0@213118|Desulfobacterales	28221|Deltaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10834_1	666681.M301_1907	4.6e-23	99.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VN53@28216|Betaproteobacteria,2KM14@206350|Nitrosomonadales	206350|Nitrosomonadales	I	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_10834_2	400668.Mmwyl1_3830	2.24e-37	132.0	COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria,1T2JB@1236|Gammaproteobacteria,1XRX9@135619|Oceanospirillales	135619|Oceanospirillales	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
k59_85738_1	335543.Sfum_1617	3.53e-38	145.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_4387_1	1165841.SULAR_09764	7.46e-85	262.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_4387_2	1165841.SULAR_09769	9.86e-49	161.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2YM7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0510	DapB_C,DapB_N
k59_92425_1	879212.DespoDRAFT_00063	8.93e-42	143.0	COG0071@1|root,COG0071@2|Bacteria,1RE2H@1224|Proteobacteria,42RP0@68525|delta/epsilon subdivisions,2WNC4@28221|Deltaproteobacteria,2MK0Y@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_119979_2	1008459.TASI_0670	5.57e-10	60.5	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,3T1JD@506|Alcaligenaceae	28216|Betaproteobacteria	C	Catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_58837_1	373903.Hore_16040	7.68e-27	108.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3WA9A@53433|Halanaerobiales	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_58837_2	1158756.AQXQ01000006_gene37	1.04e-13	69.3	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales	135613|Chromatiales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_11135_1	215803.DB30_5408	3.22e-38	137.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,42TDM@68525|delta/epsilon subdivisions,2WP8D@28221|Deltaproteobacteria,2YV8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
k59_99608_1	911239.CF149_06714	2.03e-26	108.0	2ETQP@1|root,33M8C@2|Bacteria,1QX2A@1224|Proteobacteria,1T34R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0259
k59_162415_1	1168034.FH5T_10550	4.38e-98	289.0	COG0546@1|root,COG0546@2|Bacteria,4NMPP@976|Bacteroidetes,2FS95@200643|Bacteroidia	976|Bacteroidetes	S	HAD hydrolase, family IA, variant	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_33738_1	226186.BT_1885	1.31e-114	340.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia,4AKYN@815|Bacteroidaceae	976|Bacteroidetes	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_142058_1	867900.Celly_1871	9.25e-124	369.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,1HZ6B@117743|Flavobacteriia,1F8DP@104264|Cellulophaga	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_40057_1	1401065.HMPREF2130_03165	1.92e-17	86.3	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,2VKHS@28216|Betaproteobacteria,3T6HW@506|Alcaligenaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
k59_114417_1	1232437.KL662020_gene705	1.68e-33	127.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_162419_1	1168034.FH5T_10055	1e-105	315.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,2FNR5@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_203201_1	1120954.ATXE01000004_gene29	5.74e-72	234.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4DPBE@85009|Propionibacteriales	201174|Actinobacteria	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_33747_1	1125699.HMPREF9194_00435	2.22e-71	233.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_189236_1	452652.KSE_39440	2.68e-07	53.5	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,2M2SF@2063|Kitasatospora	201174|Actinobacteria	T	Forkhead associated domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
k59_128483_2	1049564.TevJSym_aj00350	1.28e-46	166.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1J4PM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_216537_1	118168.MC7420_2502	3.65e-23	103.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,Thioesterase
k59_54020_1	1168034.FH5T_01730	1.6e-169	483.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_176080_1	1165841.SULAR_07535	9.6e-64	201.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2YMN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_176080_2	1165841.SULAR_07540	1.41e-114	330.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,42RFD@68525|delta/epsilon subdivisions,2YP9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_176080_3	387093.SUN_2217	1.82e-32	121.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2YMKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_162422_1	1168034.FH5T_07780	1.44e-41	145.0	COG1063@1|root,COG1063@2|Bacteria,4NHCK@976|Bacteroidetes,2G2S2@200643|Bacteroidia	976|Bacteroidetes	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_162422_2	1168034.FH5T_07775	3.1e-35	130.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
k59_142073_2	278957.ABEA03000094_gene4683	1.97e-20	92.0	COG0642@1|root,COG2205@2|Bacteria,46UQ3@74201|Verrucomicrobia,3K7IN@414999|Opitutae	414999|Opitutae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_94835_1	1165841.SULAR_02833	2.49e-117	338.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,42S7E@68525|delta/epsilon subdivisions,2YP7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	2-keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_73946_1	1492738.FEM21_31710	4.59e-68	221.0	COG3547@1|root,COG3547@2|Bacteria,4NF2F@976|Bacteroidetes,1HXCM@117743|Flavobacteriia,2NU5F@237|Flavobacterium	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_60982_1	1165841.SULAR_09269	2.06e-135	401.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_54026_1	1408473.JHXO01000001_gene2394	8.73e-18	83.6	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,2FQ6G@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54026_2	1168034.FH5T_05440	5.41e-27	100.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_26925_1	903818.KI912268_gene2163	9.89e-96	300.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria	57723|Acidobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_149115_2	1205680.CAKO01000035_gene159	3.71e-11	60.5	COG4197@1|root,COG4197@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	YdaS_antitoxin
k59_182662_1	338969.Rfer_2735	7.75e-08	55.1	COG2204@1|root,COG2204@2|Bacteria,1QZ6X@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_94844_1	1086011.HJ01_00870	3.13e-20	94.7	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HXMU@117743|Flavobacteriia,2P028@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_162432_1	2340.JV46_14860	2.69e-92	286.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1J4MJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CI	COG5016 Pyruvate oxaloacetate carboxyltransferase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_101492_1	1340810.V5USR5_9CAUD	1.97e-53	182.0	4QHGY@10239|Viruses,4R0DU@35237|dsDNA viruses  no RNA stage,4QRJK@28883|Caudovirales,4QI22@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_101492_3	238854.Q5GQK2_BPSYP	2.24e-18	87.4	4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses  no RNA stage,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae	10662|Myoviridae	S	DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_20216_1	870187.Thini_2167	1.03e-70	222.0	COG1556@1|root,COG1556@2|Bacteria,1RJ6A@1224|Proteobacteria,1S7WZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LUD domain	ykgG	-	-	ko:K00782	-	-	-	-	ko00000	-	-	iECO111_1330.ECO111_0342,iECO26_1355.ECO26_0342	LUD_dom
k59_169429_1	1121904.ARBP01000002_gene7145	3.28e-30	120.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_88034_1	713587.THITH_01425	4.37e-76	230.0	COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,1S2MS@1236|Gammaproteobacteria,1WY6J@135613|Chromatiales	135613|Chromatiales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
k59_216559_1	1280001.BAOA01000077_gene3069	1.01e-41	157.0	COG1361@1|root,COG2304@1|root,COG2931@1|root,COG2982@1|root,COG3121@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3121@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XSBS@135623|Vibrionales	135623|Vibrionales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind,VWA_2
k59_33785_1	29760.VIT_09s0054g00520.t01	6.4e-140	424.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	ycf1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	-	-	-	-	-	-	-	-	-	Ycf1
k59_155651_1	1366050.N234_36085	1.77e-138	405.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32
k59_94865_1	1150621.SMUL_2018	2.87e-73	231.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria	1224|Proteobacteria	L	transposase IS116 IS110 IS902 family	Z012_08285	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_176110_1	1556290.A0A0A0RM00_9CAUD	3.4e-45	165.0	4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae	10699|Siphoviridae	S	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128511_1	3847.GLYMA0973S200.1	1.26e-27	103.0	2EZXM@1|root,2T167@2759|Eukaryota,3823B@33090|Viridiplantae,3GS09@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73980_1	1165841.SULAR_08332	1.05e-114	335.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,42ME8@68525|delta/epsilon subdivisions,2YN4W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_142129_1	502025.Hoch_5743	1.28e-97	302.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria,2YZK2@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_88056_1	449447.MAE_05120	2.09e-59	196.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G3YK@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
k59_81241_1	1049564.TevJSym_ad00180	3.88e-17	82.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,1J4P6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KLT	COG0515 Serine threonine protein kinase	stk1	-	2.7.11.1	ko:K08282,ko:K11916,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,Pkinase
k59_135520_1	1165841.SULAR_00800	8.41e-116	343.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YTMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	COG4232 Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbD,Thioredoxin_2
k59_13478_1	1519464.HY22_12110	1.07e-16	90.9	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
k59_128513_1	1165841.SULAR_00105	2.21e-92	272.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2YM7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_128513_2	387093.SUN_0559	2.98e-27	110.0	COG3439@1|root,COG3439@2|Bacteria,1PWY7@1224|Proteobacteria,42Y9J@68525|delta/epsilon subdivisions,2YRF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40151_1	886377.Murru_0734	3.84e-89	270.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_40151_2	1250232.JQNJ01000001_gene656	2.11e-65	214.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_169554_1	1317122.ATO12_21020	5.35e-34	122.0	294EW@1|root,2ZRUR@2|Bacteria,4NPA3@976|Bacteroidetes,1I38U@117743|Flavobacteriia,2YJJT@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
k59_88261_1	572477.Alvin_2229	2.52e-23	91.7	2DQRC@1|root,32ZAU@2|Bacteria,1N730@1224|Proteobacteria,1SCPP@1236|Gammaproteobacteria,1WZBP@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_88261_2	667121.ET1_05_02030	8.41e-20	84.3	COG3784@1|root,COG3784@2|Bacteria,1N6R1@1224|Proteobacteria,1SC8V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ydbL	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
k59_20491_1	1249627.D779_3711	9.96e-64	213.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1WW8I@135613|Chromatiales	135613|Chromatiales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_176346_1	391603.FBALC1_12672	1.23e-47	156.0	COG0346@1|root,COG0346@2|Bacteria,4NRRY@976|Bacteroidetes,1I3EF@117743|Flavobacteriia	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_176346_2	1178540.BA70_10380	1.46e-15	75.5	arCOG03997@1|root,33T0K@2|Bacteria,1VU3K@1239|Firmicutes,4HUYD@91061|Bacilli,1ZDKK@1386|Bacillus	91061|Bacilli	S	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
k59_203474_2	1500893.JQNB01000001_gene1390	1.64e-68	217.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1X3UK@135614|Xanthomonadales	135614|Xanthomonadales	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_27261_1	1168034.FH5T_05050	4.42e-95	290.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,2FM6X@200643|Bacteroidia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_85307_1	1403819.BATR01000002_gene77	4.54e-14	79.3	COG1520@1|root,COG1520@2|Bacteria,46U9S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_31016_1	317025.Tcr_0656	1.5e-05	50.4	COG0582@1|root,COG0582@2|Bacteria,1MX7E@1224|Proteobacteria,1RNX5@1236|Gammaproteobacteria,462RH@72273|Thiotrichales	72273|Thiotrichales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
k59_166343_1	396588.Tgr7_3234	3.38e-36	135.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1WWA9@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_44211_1	1168034.FH5T_04950	8.32e-46	160.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes	976|Bacteroidetes	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_186739_1	1504981.KO116_3682	1.3e-37	140.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,1RNRG@1236|Gammaproteobacteria,1XQYS@135619|Oceanospirillales	135619|Oceanospirillales	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_179769_1	1168034.FH5T_14750	7.38e-90	276.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
k59_78362_1	1121396.KB893080_gene889	1.53e-26	106.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,42PBT@68525|delta/epsilon subdivisions,2WMAY@28221|Deltaproteobacteria,2MJ4X@213118|Desulfobacterales	28221|Deltaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_139306_1	314345.SPV1_01592	7.26e-39	139.0	2B64P@1|root,31Z1K@2|Bacteria,1RGUR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_139306_2	1128912.GMES_1832	1.01e-06	50.8	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,464MX@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_64744_1	1168034.FH5T_10080	6.17e-121	353.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_64744_2	694427.Palpr_0512	1.32e-16	78.6	COG0458@1|root,COG0505@1|root,COG0458@2|Bacteria,COG0505@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22W4Y@171551|Porphyromonadaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_132748_2	1165841.SULAR_10039	8.33e-182	509.0	COG2010@1|root,COG2010@2|Bacteria,1PDTK@1224|Proteobacteria,42N5Z@68525|delta/epsilon subdivisions,2YMTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_213817_1	1283076.M1IDH2_9CAUD	3.28e-22	104.0	4QAYA@10239|Viruses,4QVN5@35237|dsDNA viruses  no RNA stage,4QRZE@28883|Caudovirales,4QIAY@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213817_3	69279.BG36_11075	1.55e-22	94.4	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,43JP8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
k59_146269_1	7668.SPU_022296-tr	1.84e-41	156.0	COG5059@1|root,KOG1075@1|root,KOG0242@2759|Eukaryota,KOG1075@2759|Eukaryota,38GPV@33154|Opisthokonta,3BF94@33208|Metazoa,3CWIA@33213|Bilateria	33208|Metazoa	Z	microtubule motor activity	KIF22	GO:0000070,GO:0000278,GO:0000280,GO:0000775,GO:0000776,GO:0000785,GO:0000819,GO:0000902,GO:0000904,GO:0001654,GO:0001756,GO:0001966,GO:0002376,GO:0002478,GO:0002495,GO:0002504,GO:0003002,GO:0003674,GO:0003676,GO:0003677,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0005871,GO:0005875,GO:0006810,GO:0006890,GO:0006928,GO:0006996,GO:0007017,GO:0007018,GO:0007049,GO:0007059,GO:0007062,GO:0007080,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007417,GO:0007420,GO:0007423,GO:0008150,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009952,GO:0009987,GO:0015630,GO:0016043,GO:0016192,GO:0016462,GO:0016604,GO:0016607,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019882,GO:0019884,GO:0019886,GO:0021952,GO:0021953,GO:0021954,GO:0021955,GO:0022008,GO:0022402,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0035282,GO:0040011,GO:0042330,GO:0043009,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0048002,GO:0048193,GO:0048285,GO:0048468,GO:0048513,GO:0048592,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050000,GO:0050896,GO:0051179,GO:0051234,GO:0051276,GO:0051303,GO:0051310,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0060322,GO:0060429,GO:0061053,GO:0061564,GO:0070013,GO:0071840,GO:0072686,GO:0090596,GO:0097159,GO:0098687,GO:0098813,GO:0120036,GO:0120039,GO:0140014,GO:1901363,GO:1903047	-	ko:K02988,ko:K10403	ko03010,ko04914,map03010,map04914	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04812	-	-	-	HHH_3,Kinesin
k59_152994_1	301.JNHE01000003_gene1806	2.81e-07	55.5	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,1YKRX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	Type II secretion system (T2SS), protein K	gspK	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_152994_2	395493.BegalDRAFT_0545	1.98e-22	91.3	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k59_91993_1	1408473.JHXO01000006_gene1255	9.94e-91	298.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,2FNH9@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_146270_2	1192868.CAIU01000019_gene2556	4e-41	149.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2TTW3@28211|Alphaproteobacteria,43MXG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	Biotin-lipoyl like	yiaV	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
k59_105625_1	1165841.SULAR_08212	2.2e-33	120.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria	1224|Proteobacteria	NU	Sel1 domain protein repeat-containing protein	-	GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF3857,Sel1,Transglut_core
k59_105625_2	1165841.SULAR_08217	1.06e-79	241.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2YMC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0566	DAP_epimerase
k59_17351_2	1304885.AUEY01000009_gene1949	3.19e-92	281.0	COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,43CQR@68525|delta/epsilon subdivisions,2X7Y7@28221|Deltaproteobacteria,2MPPF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_78375_1	207954.MED92_09166	5.59e-37	129.0	COG2703@1|root,COG2703@2|Bacteria,1PEG5@1224|Proteobacteria,1SEQN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	oxygen carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_159739_1	323261.Noc_0279	2.17e-62	203.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1WXRI@135613|Chromatiales	135613|Chromatiales	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
k59_159739_2	478801.Ksed_20470	6.55e-17	78.6	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,1ZVJ8@145357|Dermacoccaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	sugB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_112068_1	1163617.SCD_n01153	7.17e-29	114.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_10514_1	1089552.KI911559_gene1740	8.19e-125	381.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2JPMS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_173203_1	1168034.FH5T_09805	9.01e-177	496.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,2FX9N@200643|Bacteroidia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
k59_139331_1	1408303.JNJJ01000070_gene2835	6.43e-07	57.4	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1ZBK3@1386|Bacillus	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM
k59_153006_2	7719.XP_002123084.2	6.79e-70	229.0	2CQJ9@1|root,2R501@2759|Eukaryota,39VPP@33154|Opisthokonta,3BH26@33208|Metazoa,3D1HX@33213|Bilateria,48CQC@7711|Chordata	33208|Metazoa	S	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_125843_1	1499967.BAYZ01000182_gene4457	2.3e-146	423.0	COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria	2|Bacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	cobW
k59_132770_1	1165841.SULAR_00305	2.64e-22	89.7	2FGS9@1|root,348MQ@2|Bacteria,1P3H2@1224|Proteobacteria,42SDS@68525|delta/epsilon subdivisions,2YPE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
k59_132770_2	1165841.SULAR_00310	2.26e-82	245.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,42SIJ@68525|delta/epsilon subdivisions,2YPP8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	G T U mismatch-specific DNA glycosylase	mug	-	-	-	-	-	-	-	-	-	-	-	UDG
k59_200475_1	697282.Mettu_3480	2.13e-91	297.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales	135618|Methylococcales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_78392_1	1123518.ARWI01000001_gene2416	2.21e-20	90.5	COG1595@1|root,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,1RU98@1236|Gammaproteobacteria,4632H@72273|Thiotrichales	72273|Thiotrichales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_159751_1	1168034.FH5T_08955	8.6e-57	181.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,2FPCJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_179817_1	1121878.AUGL01000014_gene1630	2.57e-69	210.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_179817_2	1279019.ARQK01000032_gene1160	7.97e-29	112.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
k59_71540_1	570268.ANBB01000048_gene3460	9.47e-22	97.1	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4EHHK@85012|Streptosporangiales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_159758_1	45351.EDO47327	5.58e-11	64.7	KOG1591@1|root,KOG1591@2759|Eukaryota,38RNT@33154|Opisthokonta,3BE11@33208|Metazoa	33208|Metazoa	E	prolyl 4-hydroxylase	P4HTM	GO:0002682,GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016706,GO:0045595,GO:0045637,GO:0045646,GO:0050789,GO:0050793,GO:0050794,GO:0051213,GO:0051239,GO:0055114,GO:0065007,GO:0065008,GO:1903706,GO:2000026	-	ko:K06711	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3,EF-hand_5,EF-hand_7
k59_92030_1	765912.Thimo_3491	8.06e-22	93.6	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1WY3A@135613|Chromatiales	135613|Chromatiales	T	SH3 domain	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k59_213840_2	1046714.AMRX01000008_gene1060	1.11e-62	194.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,46851@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_200482_1	251221.35211640	1.29e-22	104.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825,PBP_dimer,Peptidase_M56,Transpeptidase
k59_98966_1	84531.JMTZ01000038_gene3624	2.36e-50	184.0	COG3562@1|root,COG3562@2|Bacteria,1QC30@1224|Proteobacteria,1T7R1@1236|Gammaproteobacteria,1X9KH@135614|Xanthomonadales	135614|Xanthomonadales	M	Capsule polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Capsule_synth
k59_31042_4	1179778.PMM47T1_13900	3.67e-68	236.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5067,P22_portal,Pkinase
k59_58048_1	1167006.UWK_00586	1.16e-65	211.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,42PXT@68525|delta/epsilon subdivisions,2WR2Y@28221|Deltaproteobacteria,2MNE7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_78411_1	880073.Calab_1195	8.7e-69	236.0	COG0841@1|root,COG0841@2|Bacteria,2NQI6@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_92425_2	933262.AXAM01000002_gene558	0.000134	43.9	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_99369_1	1165841.SULAR_00490	3.21e-31	120.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_71917_1	1120966.AUBU01000008_gene2619	1.73e-46	167.0	COG2866@1|root,COG2866@2|Bacteria,4NH4I@976|Bacteroidetes,47MEA@768503|Cytophagia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_200751_1	754477.Q7C_859	3e-66	224.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_4389_2	1300345.LF41_505	5.98e-18	82.8	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1SKNI@1236|Gammaproteobacteria,1X5G2@135614|Xanthomonadales	135614|Xanthomonadales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_37730_1	1233488.S4T7A1_9CAUD	4.13e-16	75.5	4QEW9@10239|Viruses,4QWFV@35237|dsDNA viruses  no RNA stage,4QRGP@28883|Caudovirales,4QNCN@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_173500_1	1134474.O59_004079	8.23e-46	161.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
k59_187107_1	1122619.KB892341_gene785	9.49e-92	292.0	COG3012@1|root,COG3012@2|Bacteria,1R5E5@1224|Proteobacteria,2VZMD@28216|Betaproteobacteria,3T744@506|Alcaligenaceae	28216|Betaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,SEC-C
k59_31409_1	1165841.SULAR_07193	1.8e-32	118.0	COG2863@1|root,COG2863@2|Bacteria,1Q4WC@1224|Proteobacteria,42NFN@68525|delta/epsilon subdivisions,2YMWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Plasminogen-binding protein pgbA N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PGBA_N
k59_31409_2	1165841.SULAR_07188	8.88e-138	401.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2YMW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_10841_1	697282.Mettu_2804	4.25e-117	351.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1XE4R@135618|Methylococcales	135618|Methylococcales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
k59_65180_1	998674.ATTE01000001_gene1109	5.18e-133	383.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,46076@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
k59_133203_1	864073.HFRIS_004493	1.17e-23	103.0	2DQY9@1|root,339CR@2|Bacteria,1NR8Y@1224|Proteobacteria,2VNF6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
k59_99380_1	1123253.AUBD01000009_gene2301	8.7e-18	88.6	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X372@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	xpsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_4406_1	396588.Tgr7_0941	8.16e-114	350.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_51667_1	870187.Thini_3484	2.03e-93	285.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,1RQ8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the NifD NifK NifE NifN family	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_126232_2	1165841.SULAR_06043	1.31e-94	293.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_20585_1	1165841.SULAR_01455	5.12e-142	416.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_115437_1	1123256.KB907932_gene2946	2.46e-11	65.5	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1X4NM@135614|Xanthomonadales	135614|Xanthomonadales	C	E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_142540_1	1165841.SULAR_06083	2.86e-46	162.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,42P6Y@68525|delta/epsilon subdivisions,2YMZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_142540_2	387093.SUN_1866	6.67e-32	114.0	COG0347@1|root,COG0347@2|Bacteria,1NEHV@1224|Proteobacteria,42VRF@68525|delta/epsilon subdivisions,2YQK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61200_1	1541065.JRFE01000025_gene1938	0.000683	42.4	COG0297@1|root,COG0297@2|Bacteria,1G0PX@1117|Cyanobacteria,3VI8C@52604|Pleurocapsales	1117|Cyanobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_61200_2	2340.JV46_06570	6.82e-106	331.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_190029_1	1198232.CYCME_1998	2.02e-07	49.3	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,46175@72273|Thiotrichales	72273|Thiotrichales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_190029_2	1502770.JQMG01000001_gene1131	2.39e-10	59.7	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_190029_3	1158762.KB898037_gene2210	1.51e-24	95.5	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1SFNP@1236|Gammaproteobacteria,1X2FC@135613|Chromatiales	135613|Chromatiales	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
k59_122208_1	2340.JV46_24170	1.49e-28	114.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1J5A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k59_122208_2	2340.JV46_24140	1.75e-38	136.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1J7JW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_142542_1	767434.Fraau_2646	4.46e-141	424.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales	135614|Xanthomonadales	I	converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k59_74755_1	203122.Sde_3179	1.65e-18	89.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,4642B@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_176451_1	1165841.SULAR_08602	3.79e-46	152.0	2A1AT@1|root,30PHH@2|Bacteria,1Q6P3@1224|Proteobacteria,433GY@68525|delta/epsilon subdivisions,2YSHB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61203_1	1509403.GW12_15560	5.03e-06	50.8	COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1S4ZG@1236|Gammaproteobacteria,3NJHN@468|Moraxellaceae	1236|Gammaproteobacteria	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
k59_61203_2	227377.CBU_1295	1.09e-19	83.6	COG4118@1|root,COG4118@2|Bacteria,1QTA8@1224|Proteobacteria,1SUJ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_61203_3	398767.Glov_3572	8.53e-57	179.0	COG1487@1|root,COG1487@2|Bacteria,1N44Q@1224|Proteobacteria,42UNG@68525|delta/epsilon subdivisions,2WRVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_95104_1	1165841.SULAR_00690	3.41e-114	356.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_115445_1	207954.MED92_01029	2.1e-93	283.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,1XH81@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k59_183200_1	1502851.FG93_04163	6.2e-22	98.2	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,3JZ7W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_40884_1	314345.SPV1_12170	2.6e-41	140.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria	1224|Proteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_95108_1	1089547.KB913013_gene4280	9.21e-05	49.7	COG4675@1|root,COG4675@2|Bacteria,4NPFY@976|Bacteroidetes,47QZ4@768503|Cytophagia	976|Bacteroidetes	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k59_74763_1	1165841.SULAR_06833	2.89e-76	241.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_74763_2	1211114.ALIP01000101_gene1306	3.56e-18	77.4	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1X7EK@135614|Xanthomonadales	135614|Xanthomonadales	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_190043_1	272123.Anacy_1752	5.91e-08	55.1	28HHG@1|root,2ZF3I@2|Bacteria,1G5E6@1117|Cyanobacteria,1HN70@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27371_1	1165841.SULAR_09389	4.23e-99	304.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2YRID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13,SPOR
k59_74764_2	1168034.FH5T_12095	2.92e-55	190.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,2FMEE@200643|Bacteroidia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_142556_1	1354722.JQLS01000004_gene4292	1.42e-18	92.8	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,46RUQ@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
k59_47638_1	2340.JV46_23230	4.52e-142	410.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1J4NC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_183207_1	522306.CAP2UW1_3092	7.34e-05	45.8	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VH9H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_142558_1	1165841.SULAR_01828	2.44e-164	470.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_210372_1	313596.RB2501_06885	6.79e-10	57.8	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1HYQ9@117743|Flavobacteriia	976|Bacteroidetes	E	Lysine transporter LysE	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_210372_2	313596.RB2501_06880	6.64e-54	171.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_122217_1	1250232.JQNJ01000001_gene986	6.84e-37	140.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_47643_1	1279038.KB907339_gene1201	7.53e-05	44.7	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TUGD@28211|Alphaproteobacteria,2JQFT@204441|Rhodospirillales	204441|Rhodospirillales	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_47643_2	998674.ATTE01000001_gene3544	1.2e-48	164.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,1RR75@1236|Gammaproteobacteria,461WD@72273|Thiotrichales	72273|Thiotrichales	S	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_74768_1	556269.ACDQ01000002_gene1141	5.36e-32	118.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,473C9@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_74768_2	1353529.M899_2964	2.51e-05	47.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2MT4E@213481|Bdellovibrionales,2WK1Y@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	PFAM oxidoreductase domain protein	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_142568_1	218491.ECA3996	6.18e-56	187.0	COG0009@1|root,COG0551@1|root,COG0009@2|Bacteria,COG0551@2|Bacteria,1MX2E@1224|Proteobacteria,1RQ85@1236|Gammaproteobacteria,1MRN3@122277|Pectobacterium	1236|Gammaproteobacteria	L	Topoisomerase DNA binding C4 zinc finger	yrdD	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005506,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0097159,GO:1901363	-	ko:K07479	-	-	-	-	ko00000	-	-	-	zf-C4_Topoisom
k59_47654_1	1116472.MGMO_61c00020	3.46e-34	132.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
k59_47654_2	1279017.AQYJ01000025_gene760	2.77e-09	58.2	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_183212_1	4572.TRIUR3_09014-P1	0.000182	44.3	2EWDF@1|root,2SY7Z@2759|Eukaryota,381PD@33090|Viridiplantae,3GRPC@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_203559_1	686340.Metal_2403	2.68e-39	145.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XDVY@135618|Methylococcales	135618|Methylococcales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
k59_68055_1	401526.TcarDRAFT_0653	3.87e-21	97.8	COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4H568@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_47659_1	1144307.PMI04_00175	1.15e-66	219.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TSHC@28211|Alphaproteobacteria,2K0UX@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
k59_40924_1	582899.Hden_0689	2.61e-105	308.0	COG1150@1|root,COG1150@2|Bacteria,1R7PH@1224|Proteobacteria,2U2FE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_8
k59_20623_1	992406.RIA_0591	0.000226	50.4	COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,1I0VK@117743|Flavobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_196819_1	1121405.dsmv_0891	2.38e-33	118.0	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria,2MMAB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27396_1	1163409.UUA_11613	9e-44	153.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,1RRNV@1236|Gammaproteobacteria,1X6MJ@135614|Xanthomonadales	135614|Xanthomonadales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k59_122243_1	396595.TK90_0879	3.34e-35	137.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_136140_1	4565.Traes_2AL_F52C84040.1	4.28e-89	265.0	COG0839@1|root,2S14H@2759|Eukaryota,389Z6@33090|Viridiplantae,3GX82@35493|Streptophyta,3MAU6@4447|Liliopsida	35493|Streptophyta	P	Belongs to the complex I subunit 6 family	NAD6	-	1.6.5.3	ko:K03884	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q3
k59_75138_1	1410630.JNKP01000005_gene844	2e-49	170.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,24AER@186801|Clostridia,27J3Z@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
k59_81982_1	1027273.GZ77_22380	2.07e-44	150.0	COG1662@1|root,COG1662@2|Bacteria,1RIVU@1224|Proteobacteria,1SA15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_81982_2	1499967.BAYZ01000134_gene16	2.23e-39	133.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1,HTH_Tnp_IS1,Zn_Tnp_IS1
k59_21002_1	1168034.FH5T_01045	8.94e-75	231.0	COG2207@1|root,COG2207@2|Bacteria,4NMFW@976|Bacteroidetes,2G07E@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k59_183570_1	247634.GPB2148_1835	2.67e-24	97.1	COG1917@1|root,COG1917@2|Bacteria,1QXXM@1224|Proteobacteria,1SIKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
k59_203923_1	485913.Krac_12005	3.54e-18	86.3	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_54841_2	314275.MADE_1014600	2.18e-150	436.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
k59_197209_1	679200.HMPREF9333_02305	1.54e-21	94.0	COG2801@1|root,COG2801@2|Bacteria,1TRNK@1239|Firmicutes,24B7I@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_197209_2	443144.GM21_3075	5e-27	102.0	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria	1224|Proteobacteria	L	COG2963, Transposase and inactivated derivatives	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
k59_210770_1	395493.BegalDRAFT_1189	6.4e-13	65.9	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,1SH3A@1236|Gammaproteobacteria,463C1@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210770_2	1123400.KB904817_gene1526	7.47e-80	244.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,46080@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_27758_1	545276.KB898732_gene2445	9.87e-14	70.5	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1WY2P@135613|Chromatiales	135613|Chromatiales	J	catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_27758_2	1123400.KB904756_gene2671	1.31e-18	83.2	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,460YI@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_41266_1	679199.HMPREF9332_01334	0.000238	52.0	COG0419@1|root,COG0419@2|Bacteria,4NH9H@976|Bacteroidetes,2FPAQ@200643|Bacteroidia,1WCW5@1283313|Alloprevotella	976|Bacteroidetes	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_68428_1	1165841.SULAR_09914	1.4e-30	112.0	COG0720@1|root,COG0720@2|Bacteria,1R62M@1224|Proteobacteria,42R4Z@68525|delta/epsilon subdivisions,2YNZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_190459_1	97139.C824_01911	2.3e-19	92.4	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,24AB0@186801|Clostridia,36FBK@31979|Clostridiaceae	186801|Clostridia	G	Sucrose phosphorylase	-	-	2.4.1.329,2.4.1.7	ko:K00690,ko:K21350	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
k59_109046_2	387093.SUN_0825	1.31e-74	228.0	296U5@1|root,2ZU34@2|Bacteria,1Q4NP@1224|Proteobacteria,42ZIJ@68525|delta/epsilon subdivisions,2YRP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142926_1	242619.PG_1290	2.82e-60	195.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,22XCN@171551|Porphyromonadaceae	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_163294_1	1122599.AUGR01000015_gene2617	3.45e-36	147.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XP0I@135619|Oceanospirillales	135619|Oceanospirillales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_27762_1	2340.JV46_05960	5.82e-59	204.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
k59_190467_1	313596.RB2501_03760	4.39e-133	408.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IJBA@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_1579_1	1122603.ATVI01000012_gene1200	3.31e-30	115.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1X36H@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_69316_1	502025.Hoch_4134	4.33e-06	48.9	COG2050@1|root,COG2050@2|Bacteria,1RHAN@1224|Proteobacteria,43157@68525|delta/epsilon subdivisions,2WWIW@28221|Deltaproteobacteria,2YVGQ@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
k59_130224_1	1165841.SULAR_00265	6.75e-151	427.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2YMPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf04305	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_89773_1	7070.TC001495-PA	6.59e-40	152.0	2CMGD@1|root,2QQ9V@2759|Eukaryota,39B3J@33154|Opisthokonta,3BKG5@33208|Metazoa,3CTR5@33213|Bilateria,41V8V@6656|Arthropoda,3SQAF@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2
k59_150637_1	1165841.SULAR_05418	4.07e-108	322.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1Q55C@1224|Proteobacteria,42RCA@68525|delta/epsilon subdivisions,2YND3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	PPR
k59_184473_1	639030.JHVA01000001_gene639	1.24e-41	163.0	COG4796@1|root,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
k59_143707_1	1403819.BATR01000055_gene1716	3.94e-11	65.9	COG5414@1|root,COG5414@2|Bacteria,46VD3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	histone acetyltransferase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42099_1	1165841.SULAR_10409	6.41e-30	115.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2YMZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_42099_2	1165841.SULAR_10399	2.49e-26	97.4	COG0690@1|root,COG0690@2|Bacteria,1N8YN@1224|Proteobacteria,42VP0@68525|delta/epsilon subdivisions,2YQ7E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_42099_3	1165841.SULAR_10394	1.58e-68	210.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2YMJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_103227_2	2340.JV46_06250	3.1e-112	325.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1J60R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
k59_62624_1	1168034.FH5T_04085	9.85e-86	269.0	COG2913@1|root,COG2913@2|Bacteria,4NNWY@976|Bacteroidetes,2G3FI@200643|Bacteroidia	976|Bacteroidetes	J	COG NOG25454 non supervised orthologous group	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_137044_1	177437.HRM2_18670	1.63e-62	198.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2MJ2V@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_49042_1	749222.Nitsa_0695	1.53e-58	184.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_49042_2	1165841.SULAR_09604	3.3e-18	83.6	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_35297_1	1238182.C882_0970	5.17e-69	231.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,2JQ58@204441|Rhodospirillales	204441|Rhodospirillales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_89780_1	388413.ALPR1_21088	9.03e-89	300.0	COG1361@1|root,COG3210@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11
k59_211753_1	1168034.FH5T_06400	1.48e-38	131.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
k59_35300_1	1117647.M5M_05170	1.08e-44	148.0	COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,1J731@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3,Glutaredoxin
k59_123473_1	572477.Alvin_0770	1.22e-07	49.7	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,1S90G@1236|Gammaproteobacteria,1X29T@135613|Chromatiales	135613|Chromatiales	S	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123473_2	458817.Shal_1305	0.000115	46.2	COG0272@1|root,COG0272@2|Bacteria,1RH16@1224|Proteobacteria,1S0E5@1236|Gammaproteobacteria,2QD05@267890|Shewanellaceae	1236|Gammaproteobacteria	L	BRCA1 C Terminus (BRCT) domain	-	-	-	-	-	-	-	-	-	-	-	-	BRCT
k59_62631_2	2340.JV46_28940	1.25e-38	131.0	2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,1S7UG@1236|Gammaproteobacteria,1JAKI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130238_1	319224.Sputcn32_3399	1.51e-27	111.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,2QAQR@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_110057_1	1189612.A33Q_2380	7.07e-36	145.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_150657_1	589865.DaAHT2_2599	5.32e-158	462.0	COG3385@1|root,COG3385@2|Bacteria,1R8CS@1224|Proteobacteria,42P9F@68525|delta/epsilon subdivisions,2WKTA@28221|Deltaproteobacteria,2MJAY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_2
k59_69335_1	743720.Psefu_2619	6.6e-38	146.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_191395_1	272123.Anacy_0117	8.84e-33	129.0	COG4928@1|root,COG4928@2|Bacteria,1G1HK@1117|Cyanobacteria,1HKGM@1161|Nostocales	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
k59_157453_1	391615.ABSJ01000016_gene1735	2.9e-78	257.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1J4XZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1611_1	1168034.FH5T_14650	6.17e-40	140.0	COG0506@1|root,COG0506@2|Bacteria,4NKZB@976|Bacteroidetes,2FW9Q@200643|Bacteroidia	976|Bacteroidetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k59_137055_1	360107.CHAB381_0830	1.06e-21	93.6	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_69346_1	1249997.JHZW01000003_gene2099	1.23e-67	212.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia,2PGVZ@252356|Maribacter	976|Bacteroidetes	E	Dihydrodipicolinate reductase, C-terminus	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_184501_1	747.DR93_2068	3.51e-32	118.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1Y7FR@135625|Pasteurellales	135625|Pasteurellales	CO	Thiol disulfide interchange protein dsbE	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	Redoxin
k59_184501_2	2340.JV46_18410	5.19e-49	161.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1J6GH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	subunit of a heme lyase	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH,TPR_19
k59_110070_1	1165841.SULAR_02288	9.65e-114	336.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_90271_2	1437425.CSEC_2336	2.78e-12	65.5	COG2070@1|root,COG2070@2|Bacteria,2JGSD@204428|Chlamydiae	204428|Chlamydiae	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
k59_191775_1	1333998.M2A_0802	5.31e-12	71.2	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,4BPQ0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_144172_1	1121878.AUGL01000016_gene3246	4.68e-45	166.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
k59_56138_1	472759.Nhal_3933	7.85e-32	126.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1X0CU@135613|Chromatiales	135613|Chromatiales	H	HemY domain protein	-	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
k59_49580_1	1419583.V466_07760	2.13e-26	111.0	COG0438@1|root,COG0438@2|Bacteria,1R3TV@1224|Proteobacteria,1RQZC@1236|Gammaproteobacteria,1YUAE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
k59_137468_1	1366050.N234_25920	4.55e-98	298.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VNU5@28216|Betaproteobacteria,1K1AA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_96941_1	562970.Btus_1013	1.26e-34	133.0	COG1078@1|root,COG1078@2|Bacteria	2|Bacteria	S	dGTPase activity	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_2102_1	1165841.SULAR_07595	7.03e-158	447.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_164612_1	616991.JPOO01000003_gene1188	6.44e-29	105.0	COG0690@1|root,COG0690@2|Bacteria,4NV63@976|Bacteroidetes,1I536@117743|Flavobacteriia,23HNR@178469|Arenibacter	976|Bacteroidetes	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_164612_2	313596.RB2501_02100	5.25e-64	198.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1HWPB@117743|Flavobacteriia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_35800_1	768671.ThimaDRAFT_0050	4.45e-98	296.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_151086_1	485913.Krac_7793	1.83e-53	191.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_123963_1	760192.Halhy_0975	2.25e-08	60.8	COG0457@1|root,COG4191@1|root,COG0457@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1IQBI@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
k59_90281_1	395493.BegalDRAFT_2678	4.86e-62	210.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,45ZVF@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_76468_1	203124.Tery_2970	3.4e-07	52.4	COG1181@1|root,COG1181@2|Bacteria,1G1R5@1117|Cyanobacteria,1HA9Q@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
k59_76468_2	43989.cce_3120	4.95e-74	234.0	COG2232@1|root,COG2232@2|Bacteria,1G0SG@1117|Cyanobacteria,3KGZS@43988|Cyanothece	1117|Cyanobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_8662_1	1121875.KB907550_gene666	6.5e-119	360.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_191794_1	998088.B565_2608	2.18e-49	170.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1Y3RZ@135624|Aeromonadales	135624|Aeromonadales	T	Two component signalling adaptor domain	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_2109_1	1121439.dsat_2263	4.22e-09	58.2	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2M7T1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_2109_2	1165841.SULAR_00490	2.39e-73	236.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_49604_1	1165841.SULAR_09479	7.29e-108	317.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_178088_2	1249627.D779_3881	7.9e-42	144.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales	135613|Chromatiales	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_144198_1	1163617.SCD_n01213	4.13e-48	164.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria	28216|Betaproteobacteria	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_42567_1	1165841.SULAR_00955	1.75e-63	197.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_153877_1	1198232.CYCME_2039	5.65e-12	70.9	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,46196@72273|Thiotrichales	72273|Thiotrichales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_11363_2	1454004.AW11_02365	8.63e-156	461.0	COG3385@1|root,COG3385@2|Bacteria,1RA6A@1224|Proteobacteria,2VUMQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_112776_1	2340.JV46_24730	2.7e-100	308.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1J5N2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	bepA	GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
k59_38174_1	879212.DespoDRAFT_03471	1.73e-29	121.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_133773_2	1267535.KB906767_gene3953	7.36e-40	145.0	COG3185@1|root,COG3185@2|Bacteria,3Y2XN@57723|Acidobacteria,2JMM4@204432|Acidobacteriia	204432|Acidobacteriia	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
k59_86242_1	1168034.FH5T_09380	4.41e-111	331.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FWYQ@200643|Bacteroidia	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k59_160719_1	1165841.SULAR_03232	8.76e-113	337.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_140189_1	1041826.FCOL_01345	4.7e-27	107.0	COG3415@1|root,COG3415@2|Bacteria,4NZ4U@976|Bacteroidetes,1I6F6@117743|Flavobacteriia	976|Bacteroidetes	L	COG3415 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_33
k59_140189_2	1041826.FCOL_13515	2.35e-70	219.0	COG3335@1|root,COG3335@2|Bacteria,4NR21@976|Bacteroidetes,1I35Q@117743|Flavobacteriia	976|Bacteroidetes	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_167256_1	1165841.SULAR_06043	6.96e-57	192.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_167256_2	1165841.SULAR_06048	1.48e-78	242.0	COG1477@1|root,COG1477@2|Bacteria,1PFA4@1224|Proteobacteria,42S5P@68525|delta/epsilon subdivisions,2YPB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_72502_1	1165841.SULAR_03098	2.47e-107	326.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_65777_1	1165841.SULAR_09499	1.44e-86	258.0	COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,43B1S@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_187660_1	981223.AIED01000006_gene3443	3.83e-58	205.0	COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,1RV69@1236|Gammaproteobacteria,3NJEH@468|Moraxellaceae	1236|Gammaproteobacteria	L	Mu transposase, C-terminal	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_29,HTH_Tnp_Mu_2,Mu-transpos_C,rve
k59_79245_2	2340.JV46_07260	6.16e-55	173.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1J6C1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_99790_1	545276.KB898724_gene1881	4.03e-31	121.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_99790_2	2340.JV46_20650	3.55e-46	149.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1J6I4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_147246_1	1341181.FLJC2902T_17060	3.99e-11	65.9	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia,2NTJM@237|Flavobacterium	976|Bacteroidetes	S	peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_167268_1	331869.BAL199_05294	3.68e-143	432.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2U1PA@28211|Alphaproteobacteria,4BPCU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	psrA	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_93034_1	1144319.PMI16_00408	1.48e-20	95.9	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,473K1@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Linear gramicidin synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_160748_1	498211.CJA_2520	4.21e-44	164.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k59_31923_1	876044.IMCC3088_1387	1.47e-15	78.6	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1J5BU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_160928_1	555779.Dthio_PD1848	1.86e-224	651.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,430KD@68525|delta/epsilon subdivisions,2WVSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind
k59_214770_1	387093.SUN_0017	2.27e-24	97.1	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_214770_2	387093.SUN_0016	3.25e-67	212.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_66029_1	1123277.KB893175_gene1395	2.18e-32	120.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,47JHR@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_18618_1	4081.Solyc00g013180.1.1	1.37e-93	276.0	COG1008@1|root,KOG4845@2759|Eukaryota,37TUR@33090|Viridiplantae,3GI7Y@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_174318_1	994573.T472_0212665	1.45e-63	205.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,36DUE@31979|Clostridiaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_134016_1	1327036.R4JGG7_9CAUD	0.00061	44.3	4QENI@10239|Viruses,4QZ2F@35237|dsDNA viruses  no RNA stage,4QPXP@28883|Caudovirales,4QKPH@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_134016_2	1380346.JNIH01000064_gene5212	5.12e-09	58.9	COG5301@1|root,COG5301@2|Bacteria,2ISHQ@201174|Actinobacteria	201174|Actinobacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_99961_1	867900.Celly_1952	3.5e-17	84.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia,1F8EY@104264|Cellulophaga	976|Bacteroidetes	F	PFAM Na dependent nucleoside transporter, C-terminal	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_99961_2	1168034.FH5T_11075	2.81e-27	104.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,2FTKZ@200643|Bacteroidia	976|Bacteroidetes	S	Conserved protein	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
k59_66033_1	870187.Thini_3053	4.96e-18	84.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,461QU@72273|Thiotrichales	72273|Thiotrichales	F	N-terminal domain of ribose phosphate pyrophosphokinase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran,Pribosyltran_N
k59_45569_1	1165841.SULAR_09659	4.18e-97	305.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_174321_2	1123511.KB905852_gene3432	1.21e-05	48.9	COG1120@1|root,COG1120@2|Bacteria,1TQ6P@1239|Firmicutes,4H20I@909932|Negativicutes	909932|Negativicutes	HP	ABC transporter, ATP-binding protein	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_127001_1	102107.XP_008244832.1	2.6e-80	239.0	2C63X@1|root,2S2ZC@2759|Eukaryota,37VFD@33090|Viridiplantae,3GJPI@35493|Streptophyta,4JW29@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140350_1	765913.ThidrDRAFT_2299	3.66e-74	248.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WXAA@135613|Chromatiales	135613|Chromatiales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_167554_1	768671.ThimaDRAFT_2471	1.08e-84	262.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria,1X08U@135613|Chromatiales	135613|Chromatiales	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_120381_2	247633.GP2143_07954	5.92e-57	185.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,1SD41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_18628_1	177437.HRM2_14160	5.64e-71	238.0	COG2414@1|root,COG4992@1|root,COG2414@2|Bacteria,COG4992@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MHYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_5246_1	1211114.ALIP01000124_gene674	1.62e-38	146.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1X31T@135614|Xanthomonadales	135614|Xanthomonadales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_181093_1	933262.AXAM01000042_gene1809	1.11e-74	239.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_25157_1	631362.Thi970DRAFT_03296	1.18e-28	109.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,1S518@1236|Gammaproteobacteria,1X0QD@135613|Chromatiales	1236|Gammaproteobacteria	U	Type II secretory pathway, component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_201532_1	1260251.SPISAL_01910	1.08e-77	244.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales	135613|Chromatiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_167563_1	1165841.SULAR_01958	1.07e-87	272.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_160944_1	1168034.FH5T_21825	1.35e-83	251.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,2FMW9@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_25158_1	761193.Runsl_3068	3.56e-12	72.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_140363_1	933262.AXAM01000019_gene1091	4.56e-41	154.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MIS3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_120394_1	2340.JV46_27580	3.86e-101	318.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	ttrA	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K08357,ko:K21307	ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020	-	R10149,R10150,R11487	RC00168,RC02823,RC03109	ko00000,ko00001,ko01000,ko02000	5.A.3.10,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_147459_1	1198232.CYCME_1141	1.08e-90	273.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,463TN@72273|Thiotrichales	72273|Thiotrichales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79571_2	589865.DaAHT2_0671	4.68e-30	110.0	COG2197@1|root,COG2197@2|Bacteria,1N4GT@1224|Proteobacteria,42TY6@68525|delta/epsilon subdivisions,2WQVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_120398_1	1165841.SULAR_09369	2.3e-109	320.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	ydiY	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF3078,DUF481
k59_160951_1	1232410.KI421428_gene1211	1.49e-69	229.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43RZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Aminoacyl-tRNA editing domain	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_174352_1	28532.XP_010535813.1	2.94e-11	70.1	COG0153@1|root,KOG0631@2759|Eukaryota,37NK5@33090|Viridiplantae,3GCI8@35493|Streptophyta,3HW7C@3699|Brassicales	35493|Streptophyta	G	Galactokinase galactose-binding signature	-	-	2.7.1.46	ko:K12446	ko00520,ko01100,map00520,map01100	-	R01754	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg,Glyco_trans_1_3
k59_194871_1	395493.BegalDRAFT_2627	4.49e-96	299.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,46061@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_160957_1	1121405.dsmv_2596	1.41e-108	329.0	COG4467@1|root,COG4467@2|Bacteria	2|Bacteria	L	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_72773_1	1168034.FH5T_08890	1.37e-36	132.0	2C793@1|root,2Z9MK@2|Bacteria,4NI6K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_79586_1	1121406.JAEX01000007_gene2381	3.99e-25	105.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2MAE5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_79586_2	696747.NIES39_Q02590	1.25e-31	113.0	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria,1HBSJ@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
k59_28045_1	1298598.JCM21714_34	9.45e-32	124.0	COG1196@1|root,COG4717@1|root,COG1196@2|Bacteria,COG4717@2|Bacteria	2|Bacteria	S	serine-type aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27,DUF3584
k59_89108_1	1168034.FH5T_04910	1.14e-15	75.5	COG0726@1|root,COG0726@2|Bacteria,4NPJX@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_89108_2	1168034.FH5T_04915	6.62e-64	207.0	COG0454@1|root,COG0456@2|Bacteria,4NYFM@976|Bacteroidetes	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_82276_1	1165841.SULAR_01390	2.96e-85	253.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_7550_1	1298593.TOL_1324	8.93e-42	162.0	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,1XMP6@135619|Oceanospirillales	135619|Oceanospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_183863_1	1121859.KB890738_gene3122	1.51e-50	177.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_143233_1	977880.RALTA_A2314	3.18e-34	123.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1K3IX@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_143233_2	2340.JV46_27740	4.32e-84	259.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,1JB8I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_190757_1	103733.JNYO01000009_gene4607	7.86e-15	71.6	COG5472@1|root,COG5472@2|Bacteria,2II3H@201174|Actinobacteria,4E3QB@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted small integral membrane protein (DUF2165)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2165
k59_116124_1	395495.Lcho_2718	1.38e-11	70.1	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,1KPMM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
k59_163594_1	1279017.AQYJ01000023_gene3188	6.18e-79	258.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,465F9@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_183866_1	443255.SCLAV_5689	3.58e-74	235.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_82278_1	1165841.SULAR_05183	1.57e-88	283.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_41542_1	1165841.SULAR_06623	2.73e-85	255.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_41542_2	1165841.SULAR_06628	2.05e-37	128.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_204209_1	713587.THITH_07425	3.34e-110	339.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1SMH6@1236|Gammaproteobacteria,1X0JB@135613|Chromatiales	135613|Chromatiales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_89124_1	886293.Sinac_1231	1.44e-46	167.0	COG3464@1|root,COG3464@2|Bacteria,2J4EX@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_48357_1	195250.CM001776_gene960	1.23e-07	57.4	COG4974@1|root,COG4974@2|Bacteria,1G4JW@1117|Cyanobacteria,1GZF3@1129|Synechococcus	1117|Cyanobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_109336_1	935848.JAEN01000005_gene3824	1.42e-45	159.0	COG1073@1|root,COG1073@2|Bacteria,1QV2M@1224|Proteobacteria,2TW92@28211|Alphaproteobacteria,2PU7F@265|Paracoccus	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_21243_1	1232410.KI421413_gene827	2.31e-43	156.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
k59_883_1	1122165.AUHS01000002_gene3033	8.03e-85	268.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1JD0Z@118969|Legionellales	118969|Legionellales	IQ	AMP-binding enzyme C-terminal domain	lidS	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_116145_1	983545.Glaag_1427	1.88e-37	129.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,4683K@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_116145_2	380358.XALC_0614	4.45e-27	104.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1X30Z@135614|Xanthomonadales	135614|Xanthomonadales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_143254_1	1177181.T9A_03081	1.56e-44	151.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,1XK1Z@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
k59_89132_2	32057.KB217478_gene5388	3.73e-31	115.0	COG4636@1|root,COG4636@2|Bacteria,1G4MT@1117|Cyanobacteria,1HMD8@1161|Nostocales	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_197540_1	631362.Thi970DRAFT_03648	9.27e-05	50.1	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1WXJ3@135613|Chromatiales	135613|Chromatiales	E	PFAM Transglutaminase-like	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_190771_1	1408418.JNJH01000043_gene3127	5.08e-30	119.0	2FITE@1|root,34AIX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136417_1	990073.ATHU01000001_gene253	1.43e-09	56.6	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2YP5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase maturation protease	hydD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_136417_2	1165841.SULAR_02933	6.12e-76	233.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	hydC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_183876_1	395493.BegalDRAFT_2591	2.63e-93	284.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,460SY@72273|Thiotrichales	72273|Thiotrichales	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_21586_1	313596.RB2501_05265	5.04e-82	256.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1HXKA@117743|Flavobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_35113_1	1165841.SULAR_09759	2.35e-100	294.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2YNQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_157165_1	1168034.FH5T_20260	7.04e-69	219.0	COG2273@1|root,COG2273@2|Bacteria,4NQU3@976|Bacteroidetes,2FT4I@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_191119_1	768671.ThimaDRAFT_4890	3.73e-63	205.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1WWFP@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k59_28516_1	1236541.BALL01000068_gene4802	9.23e-08	51.6	COG0784@1|root,COG0784@2|Bacteria,1QFXP@1224|Proteobacteria,1TD92@1236|Gammaproteobacteria,2QE4T@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_28516_2	1123326.JFBL01000002_gene1767	2.84e-33	126.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_48794_1	1165841.SULAR_01080	9.13e-63	213.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,42ZJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_82719_2	2340.JV46_18840	1.15e-125	366.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1J4GT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_14890_1	1165841.SULAR_09294	1.44e-94	278.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_35119_1	1165841.SULAR_01618	4.27e-110	320.0	COG0745@1|root,COG0745@2|Bacteria,1R9AZ@1224|Proteobacteria,42NYS@68525|delta/epsilon subdivisions,2YNW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	response regulator	dccR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_35119_2	1165841.SULAR_01623	5.15e-66	211.0	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_197940_1	1255043.TVNIR_0911	1.73e-219	618.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1WYPQ@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_191125_1	2340.JV46_15420	1.08e-110	322.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
k59_116667_1	1406840.Q763_12565	6.04e-17	79.7	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1HY99@117743|Flavobacteriia,2NSKX@237|Flavobacterium	976|Bacteroidetes	E	Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_116667_2	997353.HMPREF9144_2148	1.72e-23	98.6	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia	976|Bacteroidetes	O	ATPase histidine kinase DNA gyrase B HSP90 domain protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_123257_1	886293.Sinac_7397	4.12e-65	213.0	COG1861@1|root,COG1861@2|Bacteria,2J3F7@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_184236_1	314285.KT71_08620	4.83e-187	527.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1J9WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_21596_1	1122185.N792_13355	8.63e-90	280.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1X4BQ@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_197945_1	870187.Thini_4305	1.49e-47	172.0	COG2358@1|root,COG3597@1|root,COG2358@2|Bacteria,COG3597@2|Bacteria,1QEZ0@1224|Proteobacteria,1S3C0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
k59_48801_1	756272.Plabr_2666	7.86e-51	177.0	COG0480@1|root,COG0480@2|Bacteria,2IXUD@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_184237_1	1165841.SULAR_06903	3.61e-49	171.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_157188_1	1165841.SULAR_05448	1.4e-06	48.9	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_157188_3	1165841.SULAR_05458	2.03e-51	165.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2YP8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_177431_1	1116472.MGMO_157c00100	3.12e-35	138.0	2EF1J@1|root,338UN@2|Bacteria,1P071@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41895_1	709032.Sulku_1992	1.63e-52	167.0	COG3370@1|root,COG3370@2|Bacteria,1N27G@1224|Proteobacteria,42UAJ@68525|delta/epsilon subdivisions,2YPZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_41895_2	1242969.ATCC51562_441	2.08e-15	75.1	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_28532_1	1165841.SULAR_04622	1.01e-105	311.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_197953_1	1165841.SULAR_00785	1.97e-126	361.0	COG2227@1|root,COG2227@2|Bacteria,1R74R@1224|Proteobacteria,43CZS@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	HMA,Methyltransf_11,Methyltransf_25,TPMT
k59_96235_1	1167006.UWK_00638	2.12e-65	216.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WQGS@28221|Deltaproteobacteria,2MP5P@213118|Desulfobacterales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_150432_2	1168034.FH5T_17650	3.89e-130	370.0	COG1595@1|root,COG1595@2|Bacteria,4NVR6@976|Bacteroidetes	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
k59_62367_1	1122134.KB893650_gene1288	1.16e-48	162.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_197957_1	1485545.JQLW01000005_gene945	1.09e-47	155.0	COG2402@1|root,COG2402@2|Bacteria,1N28Q@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
k59_197957_2	641524.ADICYQ_2579	1.67e-08	53.9	2DMNP@1|root,32SQ4@2|Bacteria,4NT2A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1352_1	395493.BegalDRAFT_0278	3.15e-254	709.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_35134_1	1165841.SULAR_02663	8.32e-106	321.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_82747_2	1269813.ATUL01000036_gene703	3e-20	84.7	COG3514@1|root,COG3514@2|Bacteria,1N7UF@1224|Proteobacteria,1SE0J@1236|Gammaproteobacteria,1X1NQ@135613|Chromatiales	135613|Chromatiales	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
k59_82747_3	1158146.KB907126_gene1590	3.15e-13	65.1	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,1SDIE@1236|Gammaproteobacteria,1WZPU@135613|Chromatiales	135613|Chromatiales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
k59_193627_1	1499967.BAYZ01000134_gene16	4.01e-05	43.9	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1,HTH_Tnp_IS1,Zn_Tnp_IS1
k59_193627_2	1027273.GZ77_22380	4.87e-36	128.0	COG1662@1|root,COG1662@2|Bacteria,1RIVU@1224|Proteobacteria,1SA15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_132701_1	156889.Mmc1_3249	3.91e-71	240.0	COG0841@1|root,COG3087@1|root,COG0841@2|Bacteria,COG3087@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_3923_1	1366050.N234_04755	1.2e-77	253.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,1K0FS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_91938_1	1165841.SULAR_05993	4.17e-93	281.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_200427_1	1168034.FH5T_04715	2.58e-79	254.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,2FMIK@200643|Bacteroidia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_193634_2	287.DR97_3829	7.62e-25	100.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1YF81@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_105573_1	1165841.SULAR_09259	5.89e-74	226.0	COG2843@1|root,COG2843@2|Bacteria,1RCV8@1224|Proteobacteria,42UIX@68525|delta/epsilon subdivisions,2YRGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
k59_125785_2	909663.KI867150_gene1831	1.33e-27	110.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MRQY@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_159694_1	1165841.SULAR_03827	4.05e-63	197.0	COG0586@1|root,COG0586@2|Bacteria,1NBBA@1224|Proteobacteria,42MFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_166322_1	1379698.RBG1_1C00001G1161	7.4e-45	160.0	COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_213801_1	511680.BUTYVIB_00341	5.29e-39	148.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,4BWTE@830|Butyrivibrio	186801|Clostridia	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_23998_1	1255043.TVNIR_3280	5.46e-101	309.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,1RYKV@1236|Gammaproteobacteria,1X06D@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_159700_1	395493.BegalDRAFT_2065	4.65e-21	97.1	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1QW47@1224|Proteobacteria,1RQU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
k59_213802_1	71139.XP_010064529.1	9.79e-07	54.7	KOG0406@1|root,KOG0406@2759|Eukaryota	2759|Eukaryota	O	glutathione transferase activity	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N
k59_57973_1	1137281.D778_02331	7.77e-14	69.3	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
k59_51196_1	1266909.AUAG01000015_gene2739	6.9e-50	179.0	COG0004@1|root,COG0642@1|root,COG0004@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07646,ko:K07679	ko02020,ko05133,map02020,map05133	M00454,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_207246_1	1449050.JNLE01000003_gene1850	8.02e-19	90.1	COG4916@1|root,COG4916@2|Bacteria,1US40@1239|Firmicutes,24UZ0@186801|Clostridia	186801|Clostridia	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
k59_44194_1	1249627.D779_0912	2.73e-44	147.0	COG3118@1|root,COG3118@2|Bacteria,1RI6E@1224|Proteobacteria,1S8B4@1236|Gammaproteobacteria,1WYJW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	Thioredoxin
k59_91955_1	313596.RB2501_06895	4.54e-119	362.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_92300_1	640081.Dsui_0048	1.16e-64	207.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,2KUQQ@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_186976_1	75379.Tint_1656	1.82e-21	93.2	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	cbbR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_78590_1	118161.KB235922_gene396	2.33e-93	281.0	COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_112266_1	1165841.SULAR_10264	2.62e-113	334.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2YN5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_24374_1	1168034.FH5T_16880	2.83e-35	134.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,2FNT9@200643|Bacteroidia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_24374_2	1168034.FH5T_16885	1.61e-22	92.4	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,2FMNQ@200643|Bacteroidia	976|Bacteroidetes	M	NlpC P60 family	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
k59_214014_2	399739.Pmen_0298	1.89e-37	133.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1SDU8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_133047_1	391598.FBBAL38_12160	3.3e-45	154.0	COG0583@1|root,COG0583@2|Bacteria,4NGHS@976|Bacteroidetes,1HXYJ@117743|Flavobacteriia	976|Bacteroidetes	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_126078_1	1328313.DS2_04775	5.55e-110	328.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,463Z5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_126078_2	1128912.GMES_1004	2.81e-75	244.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,465BK@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_105932_1	314278.NB231_17423	3.9e-85	268.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales	135613|Chromatiales	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_24385_1	62928.azo1001	1.59e-50	174.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,2KUHR@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
k59_51513_1	1165841.SULAR_01100	7.11e-47	160.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_51513_2	1165841.SULAR_01105	7.96e-47	157.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_31265_1	155515.JP36_05145	3.33e-12	70.1	COG3676@1|root,COG3676@2|Bacteria,1R7ZF@1224|Proteobacteria,1S6YQ@1236|Gammaproteobacteria,1Y7XM@135625|Pasteurellales	135625|Pasteurellales	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
k59_146586_1	1179773.BN6_32470	1.37e-56	200.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4E2GQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_17714_1	765912.Thimo_0720	3.75e-70	221.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales	135613|Chromatiales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_65044_1	702113.PP1Y_AT4598	3.13e-90	278.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TR8I@28211|Alphaproteobacteria,2K2N9@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_85615_1	1123502.AQXD01000002_gene525	2.92e-60	202.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1X4MX@135614|Xanthomonadales	135614|Xanthomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_10756_1	1165841.SULAR_07370	9.9e-88	268.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2YMR3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_10756_2	387093.SUN_2166	1.01e-06	46.6	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2YPX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_153280_1	57918.XP_004300707.1	3.51e-83	256.0	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae,3GHHH@35493|Streptophyta,4JTJR@91835|fabids	35493|Streptophyta	O	mitochondrial protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve
k59_173416_1	395493.BegalDRAFT_1704	4.75e-113	329.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,46210@72273|Thiotrichales	72273|Thiotrichales	S	CcmB protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_17724_1	1121405.dsmv_2856	6.77e-31	124.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_51529_2	387093.SUN_0974	1.72e-27	111.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42NGE@68525|delta/epsilon subdivisions,2YN37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_58344_1	1168034.FH5T_07950	4.56e-114	348.0	COG4772@1|root,COG4772@2|Bacteria,4NF0U@976|Bacteroidetes,2FM7N@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_112290_1	316274.Haur_3961	2.18e-38	147.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,2G68I@200795|Chloroflexi,3765Y@32061|Chloroflexia	2|Bacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
k59_207590_1	1304885.AUEY01000041_gene3689	2.42e-90	278.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria,2MN57@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_78631_1	1165841.SULAR_01718	4.63e-19	85.1	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1N68I@1224|Proteobacteria,43BAI@68525|delta/epsilon subdivisions,2YT7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_78631_2	1165841.SULAR_01713	2.2e-60	196.0	COG0811@1|root,COG0811@2|Bacteria,1QUIX@1224|Proteobacteria,42MTG@68525|delta/epsilon subdivisions,2YMAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_187011_1	941449.dsx2_2275	8.45e-24	104.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MGAF@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC-2 type transporter	ybhR	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_85630_1	1442598.JABW01000031_gene1279	8.11e-24	93.6	COG2963@1|root,COG2963@2|Bacteria,1QWYW@1224|Proteobacteria,432XW@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Protein of unknown function (DUF2805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2805
k59_85630_2	1442598.JABW01000031_gene1276	1.22e-40	149.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,42QR0@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_105972_1	425104.Ssed_3079	6.35e-15	79.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,2Q9ZA@267890|Shewanellaceae	1236|Gammaproteobacteria	N	TIGRFAM flagellar rod assembly protein muramidase FlgJ	flgJ	GO:0003674,GO:0005198	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k59_214040_1	1168034.FH5T_07900	5.77e-17	74.3	2FH9E@1|root,3493R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160083_1	4565.Traes_2AL_33F114DA3.1	1.48e-118	352.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,3GEEJ@35493|Streptophyta,3KME8@4447|Liliopsida,3IAIW@38820|Poales	35493|Streptophyta	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cox1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k59_4284_1	1165841.SULAR_03123	2.11e-85	261.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,42RT7@68525|delta/epsilon subdivisions,2YRF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_65065_1	1232437.KL661994_gene354	6.49e-100	301.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria,2MKFC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_214042_1	502025.Hoch_0170	1.15e-72	229.0	COG1409@1|root,COG1409@2|Bacteria,1R70J@1224|Proteobacteria,437FQ@68525|delta/epsilon subdivisions,2X2NB@28221|Deltaproteobacteria,2YTZ0@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_4289_1	313596.RB2501_14289	9.53e-121	367.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_166657_1	1165841.SULAR_00295	4.52e-117	345.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_180158_1	1565129.JSFF01000006_gene2556	3.76e-76	234.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RPSX@1236|Gammaproteobacteria,2QCFS@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadB1x	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_200696_1	592027.CLG_B0569	1.87e-64	203.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24JC8@186801|Clostridia,36RET@31979|Clostridiaceae	186801|Clostridia	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_153307_1	265072.Mfla_0738	4.83e-07	56.6	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,2KN2F@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_139640_1	1042375.AFPL01000046_gene2010	1.98e-76	235.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,466EB@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_129561_2	479431.Namu_2611	5.5e-27	108.0	COG1280@1|root,COG1280@2|Bacteria,2HRC6@201174|Actinobacteria,4EVHM@85013|Frankiales	201174|Actinobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
k59_183817_1	243233.MCA1426	5.39e-23	94.7	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,1SHZQ@1236|Gammaproteobacteria,1XFXG@135618|Methylococcales	135618|Methylococcales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_183817_2	1201292.DR75_1015	1.95e-05	49.3	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,4HE8D@91061|Bacilli,4B0UB@81852|Enterococcaceae	91061|Bacilli	M	Glycosyltransferase like family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_95688_1	1250232.JQNJ01000001_gene971	9.03e-38	127.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_95688_2	983548.Krodi_1384	6.78e-32	120.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia,37EQ3@326319|Dokdonia	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_136356_1	321332.CYB_0121	3.15e-29	114.0	COG0821@1|root,COG0821@2|Bacteria,1G1GY@1117|Cyanobacteria,1GYGB@1129|Synechococcus	1117|Cyanobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.gcpE	GcpE
k59_183824_1	1173025.GEI7407_1885	5.32e-58	192.0	COG4638@1|root,COG4638@2|Bacteria,1G4PW@1117|Cyanobacteria,1HCQP@1150|Oscillatoriales	1117|Cyanobacteria	P	large terminal subunit'	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
k59_204169_1	743722.Sph21_1756	1.05e-62	217.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1INWH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycoside hydrolase, family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_143186_1	765913.ThidrDRAFT_2298	3.52e-73	233.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1WWE4@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23
k59_96353_2	1168034.FH5T_06450	1.06e-45	155.0	28NPZ@1|root,2ZBPQ@2|Bacteria,4NN3K@976|Bacteroidetes,2FPEH@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_41976_2	1165841.SULAR_02448	6.39e-45	147.0	2CBEP@1|root,32RT7@2|Bacteria,1MZXD@1224|Proteobacteria,42VUE@68525|delta/epsilon subdivisions,2YQCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62472_1	1117318.PRUB_06415	3.66e-10	64.7	COG2203@1|root,COG3292@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RRSF@1236|Gammaproteobacteria,2Q48I@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase with beta propeller sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,Reg_prop,Y_Y_Y
k59_177507_1	4513.MLOC_76383.1	9.4e-15	67.8	28YPX@1|root,2R5HW@2759|Eukaryota,386B3@33090|Viridiplantae,3GU83@35493|Streptophyta,3M8JJ@4447|Liliopsida,3ISVX@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14987_1	1121920.AUAU01000004_gene791	2.96e-20	94.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
k59_21696_1	1442599.JAAN01000032_gene1552	2.09e-67	206.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1X6K2@135614|Xanthomonadales	135614|Xanthomonadales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_21696_2	1279019.ARQK01000024_gene2509	2.01e-19	81.3	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales	135613|Chromatiales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_136914_1	237368.SCABRO_03007	1.5e-93	291.0	2A1MP@1|root,30PVX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109884_1	1215114.BBIU01000029_gene3444	5.03e-62	199.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_62478_1	1449347.JQLN01000007_gene1751	6.38e-36	132.0	COG0604@1|root,COG0604@2|Bacteria,2GIWC@201174|Actinobacteria,2M0FI@2063|Kitasatospora	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
k59_82869_1	9986.ENSOCUP00000005072	6.42e-25	103.0	COG2988@1|root,2QRAK@2759|Eukaryota,39S2G@33154|Opisthokonta,3BF8M@33208|Metazoa,3CX8W@33213|Bilateria,4840C@7711|Chordata,4953E@7742|Vertebrata,3JEDI@40674|Mammalia,35CS9@314146|Euarchontoglires	33208|Metazoa	E	aspartoacylase activity	ASPA	GO:0003674,GO:0003824,GO:0004046,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006520,GO:0006531,GO:0006533,GO:0006807,GO:0007272,GO:0007275,GO:0007399,GO:0007417,GO:0008150,GO:0008152,GO:0008366,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0010001,GO:0010720,GO:0014003,GO:0014013,GO:0014015,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0016999,GO:0017144,GO:0019752,GO:0019807,GO:0021782,GO:0022008,GO:0022010,GO:0030154,GO:0032291,GO:0032501,GO:0032502,GO:0032787,GO:0042063,GO:0042552,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045595,GO:0045597,GO:0045685,GO:0045687,GO:0046394,GO:0046395,GO:0048468,GO:0048518,GO:0048522,GO:0048699,GO:0048709,GO:0048713,GO:0048714,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051239,GO:0051240,GO:0051960,GO:0051962,GO:0060284,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:2000026	3.5.1.15	ko:K01437	ko00250,ko00340,ko01100,map00250,map00340,map01100	-	R00488,R00526	RC00064,RC00165,RC00300,RC00323	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k59_82869_2	1165841.SULAR_02573	3.83e-109	322.0	COG5239@1|root,COG5239@2|Bacteria,1QZF3@1224|Proteobacteria,42XN9@68525|delta/epsilon subdivisions,2YR35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	A	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_198064_1	1116472.MGMO_37c00290	1.47e-12	68.6	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XF7V@135618|Methylococcales	135618|Methylococcales	M	Belongs to the skp family	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_8088_1	1165841.SULAR_09139	5.05e-47	154.0	2BM55@1|root,32FNN@2|Bacteria,1Q0P6@1224|Proteobacteria,42SB7@68525|delta/epsilon subdivisions,2YPGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA replication regulator	hobA	-	-	-	-	-	-	-	-	-	-	-	HobA
k59_8088_2	1165841.SULAR_09144	7.93e-117	344.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_103114_1	1442598.JABW01000017_gene1945	7.27e-207	586.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2YRPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_89671_1	1123228.AUIH01000091_gene569	2.43e-74	248.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
k59_82880_2	395493.BegalDRAFT_2568	1.95e-27	110.0	COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,1S0R5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_62493_1	470145.BACCOP_01058	1.44e-56	199.0	COG1554@1|root,COG2755@1|root,COG1554@2|Bacteria,COG2755@2|Bacteria,4NEWW@976|Bacteroidetes,2FMF9@200643|Bacteroidia,4AMRU@815|Bacteroidaceae	976|Bacteroidetes	G	COG NOG04001 non supervised orthologous group	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
k59_130118_1	1429916.X566_19790	0.000104	43.1	COG3686@1|root,COG3686@2|Bacteria,1RAEH@1224|Proteobacteria,2U5JJ@28211|Alphaproteobacteria,3JY5A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MAPEG family	MA20_30600	-	-	-	-	-	-	-	-	-	-	-	MAPEG
k59_130118_2	745776.DGo_CA1316	1.99e-32	121.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	dhaR5	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k59_8104_1	283942.IL2591	3.22e-61	200.0	COG0701@1|root,COG0701@2|Bacteria,1NC9F@1224|Proteobacteria,1RYKB@1236|Gammaproteobacteria,2QFH2@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_116830_1	1165841.SULAR_05493	1.26e-99	299.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_177539_1	1029823.AFIE01000001_gene2103	3.5e-113	339.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,3NJ0S@468|Moraxellaceae	1236|Gammaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_15021_1	314285.KT71_12045	3.09e-87	268.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1J570@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	oadB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008948,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044464,GO:0055114,GO:0071944	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_157331_1	313596.RB2501_03515	7.7e-75	238.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1HWPI@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_123360_1	1168034.FH5T_20355	5.75e-139	414.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes	976|Bacteroidetes	E	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_103133_1	1165841.SULAR_00425	1.49e-192	547.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_8111_1	29730.Gorai.001G167800.1	1.22e-77	239.0	COG1007@1|root,KOG4668@2759|Eukaryota,382PB@33090|Viridiplantae,3GQMA@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_204702_1	697282.Mettu_1749	1.44e-81	257.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1XE6S@135618|Methylococcales	135618|Methylococcales	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
k59_8113_1	298386.PBPRA3352	3.71e-16	83.2	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales	135623|Vibrionales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_198117_1	1117319.PSPO_14493	2.88e-45	163.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q1FC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_55696_1	1165841.SULAR_08262	7.52e-95	288.0	29VY7@1|root,30HGA@2|Bacteria,1Q32U@1224|Proteobacteria,42WPE@68525|delta/epsilon subdivisions,2YQKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_89685_1	1007103.AFHW01000007_gene4345	2.51e-21	90.1	COG3415@1|root,COG3415@2|Bacteria,1VHWW@1239|Firmicutes,4I7ZS@91061|Bacilli,26YD3@186822|Paenibacillaceae	91061|Bacilli	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_89685_2	102129.Lepto7375DRAFT_0248	3.27e-126	363.0	COG3335@1|root,COG3335@2|Bacteria,1G5W5@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_109940_1	1165841.SULAR_06143	5.82e-106	314.0	COG2404@1|root,COG2404@2|Bacteria,1NHB1@1224|Proteobacteria,42NB0@68525|delta/epsilon subdivisions,2YMQ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
k59_170911_1	2340.JV46_06570	2.24e-95	301.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_184363_1	1165841.SULAR_09094	6.79e-15	73.2	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_184363_2	1165841.SULAR_09099	8.41e-57	182.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,42NNI@68525|delta/epsilon subdivisions,2YNBH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,Methyltransf_31
k59_136956_1	387093.SUN_1237	5.93e-148	422.0	COG0561@1|root,COG0561@2|Bacteria,1Q5G6@1224|Proteobacteria,42R7D@68525|delta/epsilon subdivisions,2YP2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_157348_1	403833.Pmob_1700	8.51e-61	211.0	COG0458@1|root,COG0458@2|Bacteria,2GDV8@200918|Thermotogae	200918|Thermotogae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_150568_1	706587.Desti_4231	1.38e-94	286.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,42RIK@68525|delta/epsilon subdivisions,2WNDV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_109949_1	631362.Thi970DRAFT_04985	7.41e-40	148.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1R97Q@1224|Proteobacteria,1RRDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_130148_1	10689.H9C0C7_BPCPT	1.96e-19	93.2	4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses  no RNA stage,4QPTC@28883|Caudovirales,4QJW3@10662|Myoviridae	10662|Myoviridae	S	Pfam:Terminase_6C	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75905_1	1033802.SSPSH_001413	1.2e-21	94.0	COG0811@1|root,COG0811@2|Bacteria,1PPAP@1224|Proteobacteria,1SEK5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_75905_2	1033802.SSPSH_001412	1.04e-23	96.3	28NA5@1|root,2ZBDZ@2|Bacteria,1MXY5@1224|Proteobacteria,1S45N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15037_2	1041138.KB890246_gene5529	1.59e-53	193.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,4B7J0@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_1516_1	1165841.SULAR_03567	6.19e-106	329.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Belongs to the peptidase S16 family	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_198137_1	748280.NH8B_2436	4.72e-08	61.2	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQNU@206351|Neisseriales	206351|Neisseriales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4
k59_69222_1	1049564.TevJSym_ac00040	2.69e-57	184.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria,1JBG1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC-2 family transporter protein	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
k59_69222_2	1049564.TevJSym_ac00050	1.73e-21	89.7	COG4314@1|root,COG4314@2|Bacteria,1N3G0@1224|Proteobacteria,1SPJU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
k59_62552_1	1317118.ATO8_21086	1.13e-56	197.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,2TS1X@28211|Alphaproteobacteria,4KNI4@93682|Roseivivax	28211|Alphaproteobacteria	M	Cellulose synthase	celA	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glycos_transf_2,PilZ
k59_8141_2	1095769.CAHF01000006_gene1808	1.4e-07	56.6	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_198146_1	1165841.SULAR_01993	1.55e-99	318.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_96425_1	754476.Q7A_2113	6.44e-85	280.0	COG2203@1|root,COG5001@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4609X@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4
k59_28731_1	500640.CIT292_08412	3.21e-15	77.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,3WWCE@544|Citrobacter	1236|Gammaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_28731_2	34506.g5952	5.71e-16	77.4	COG0389@1|root,COG0790@1|root,COG1278@1|root,KOG1550@2759|Eukaryota,KOG2093@2759|Eukaryota,KOG3070@2759|Eukaryota,3965V@33154|Opisthokonta,3CAJ3@33208|Metazoa,3DEHJ@33213|Bilateria,40PNC@6231|Nematoda,1M75G@119089|Chromadorea,415RG@6236|Rhabditida	33208|Metazoa	L	Domain of unknown function (DUF4113)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4113,IMS
k59_96430_1	395493.BegalDRAFT_3164	2.33e-103	309.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,45ZNN@72273|Thiotrichales	72273|Thiotrichales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_198156_1	1349822.NSB1T_08125	1.11e-31	129.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,22WGY@171551|Porphyromonadaceae	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_96433_1	1168034.FH5T_18355	1.93e-47	168.0	COG0438@1|root,COG1011@1|root,COG0438@2|Bacteria,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	2.4.1.270,3.1.3.102,3.1.3.104	ko:K07025,ko:K20862,ko:K21369	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1,HAD_2
k59_96433_2	1168034.FH5T_18350	3.7e-60	198.0	COG0438@1|root,COG0438@2|Bacteria,4P01C@976|Bacteroidetes	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_31636_1	1517681.HW45_12540	5.89e-33	123.0	COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,1RMJK@1236|Gammaproteobacteria,1XSNP@135623|Vibrionales	135623|Vibrionales	M	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
k59_160415_1	998674.ATTE01000001_gene4590	2.04e-62	208.0	COG5383@1|root,COG5383@2|Bacteria,1P16G@1224|Proteobacteria,1RR9P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ydcJ	-	-	-	-	-	-	-	-	-	-	-	DUF1338
k59_99525_1	981085.XP_010086549.1	3.95e-32	115.0	COG1007@1|root,KOG4668@2759|Eukaryota,37WWH@33090|Viridiplantae,3GKTY@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_139892_1	1121931.AUHG01000016_gene1001	2.04e-21	99.0	COG2271@1|root,COG2271@2|Bacteria,4NK2M@976|Bacteroidetes,1I107@117743|Flavobacteriia	976|Bacteroidetes	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_180474_1	1537994.JQFW01000042_gene2212	4.2e-20	95.1	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1T1YU@1236|Gammaproteobacteria,46D6C@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Y_Y_Y domain	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HisKA,Hpt,MASE1,Reg_prop,Response_reg,Y_Y_Y
k59_207878_1	1168034.FH5T_01510	2.74e-44	164.0	COG0577@1|root,COG0577@2|Bacteria,4NZYZ@976|Bacteroidetes,2FWFC@200643|Bacteroidia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_4934_1	1121289.JHVL01000009_gene1416	1.8e-55	192.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,36E1T@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,DUF3369,GAF_2,GGDEF,HD,HD_5,Response_reg
k59_160622_1	1121013.P873_04475	2.1e-76	251.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1X4DX@135614|Xanthomonadales	135614|Xanthomonadales	P	Nitric oxide reductase large subunit	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
k59_106610_1	1085623.GNIT_3021	2.57e-94	287.0	COG1073@1|root,COG1073@2|Bacteria,1QY08@1224|Proteobacteria,1SJFT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79128_1	309807.SRU_0109	3.68e-28	109.0	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1
k59_86176_1	1165841.SULAR_06743	1.22e-105	315.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2YMBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_86176_2	1165841.SULAR_06748	3.1e-52	170.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2YN11@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_201175_2	443144.GM21_1836	3.04e-06	53.5	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,43T72@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_38086_1	1236959.BAMT01000011_gene3218	2.98e-167	483.0	COG0286@1|root,COG5502@1|root,COG0286@2|Bacteria,COG5502@2|Bacteria,1MW3A@1224|Proteobacteria,2VK6V@28216|Betaproteobacteria	28216|Betaproteobacteria	V	type I restriction-modification	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_18329_1	1165841.SULAR_05878	1.15e-97	297.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,42PS0@68525|delta/epsilon subdivisions,2YMQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M20
k59_18329_2	387093.SUN_1807	2.31e-66	209.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_208107_1	1168034.FH5T_04250	5.02e-50	177.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein, OMP85 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_187580_1	7668.SPU_003151-tr	2.25e-22	97.4	KOG1075@1|root,KOG1075@2759|Eukaryota,3A7X5@33154|Opisthokonta,3BTPZ@33208|Metazoa,3D9N3@33213|Bilateria	33208|Metazoa	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1891,RVT_1
k59_140116_1	391600.ABRU01000008_gene2797	6.57e-16	83.2	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria,2KICB@204458|Caulobacterales	204458|Caulobacterales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_11280_1	1049564.TevJSym_bw00080	1.91e-109	330.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1J5FV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_99725_3	1283340.Q6WHE3_BPKVM	4.21e-48	164.0	4QAWI@10239|Viruses,4QW40@35237|dsDNA viruses  no RNA stage,4QPUX@28883|Caudovirales,4QINW@10662|Myoviridae	10662|Myoviridae	S	Pfam:Peptidase_S77	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160630_1	2340.JV46_05750	1.67e-21	93.6	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1J523@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_160630_2	754476.Q7A_2047	1.3e-74	227.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,460NY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_160630_3	519989.ECTPHS_10916	8.55e-26	103.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1WWXU@135613|Chromatiales	135613|Chromatiales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_153828_1	63737.Npun_R2082	5.62e-05	52.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HIST@1161|Nostocales	1117|Cyanobacteria	Q	acyl transferase domain	-	-	-	ko:K16128	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Aminotran_1_2,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_147164_1	2340.JV46_24170	8.63e-118	348.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1J5A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k59_140120_1	638303.Thal_0657	6.29e-68	216.0	COG3329@1|root,COG3329@2|Bacteria	2|Bacteria	S	Na+-dependent bicarbonate transporter superfamily	sbtA	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
k59_72402_2	1128421.JAGA01000003_gene3182	2.02e-42	155.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
k59_58960_1	1042375.AFPL01000022_gene2531	7.32e-78	243.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,464MX@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_31843_1	1123368.AUIS01000007_gene2682	2.05e-14	73.9	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,2NBTJ@225057|Acidithiobacillales	225057|Acidithiobacillales	CP	NADH Ubiquinone plastoquinone (Complex I)	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_31843_2	765912.Thimo_2946	5.65e-93	298.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WWPR@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_214490_1	1165841.SULAR_09839	2.19e-107	329.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_153835_1	1168034.FH5T_03065	1.05e-59	187.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,2FNZ6@200643|Bacteroidia	976|Bacteroidetes	C	COG1905 NADH ubiquinone oxidoreductase 24 kD subunit	hndA	-	1.12.1.3	ko:K18330	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
k59_153835_2	1168034.FH5T_03060	3.45e-36	129.0	COG2267@1|root,COG2267@2|Bacteria,4PKKD@976|Bacteroidetes	976|Bacteroidetes	I	COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_126773_1	1121920.AUAU01000011_gene183	4.85e-73	239.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,3Y85P@57723|Acidobacteria	57723|Acidobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,Guanylate_cyc
k59_65690_1	305700.B447_14449	3.74e-26	103.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2VMVW@28216|Betaproteobacteria,2KW3A@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k59_187598_1	318161.Sden_3407	3.63e-14	71.6	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,2QA78@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcHS_1320.EcHS_A4240,iPC815.YPO3728	AICARFT_IMPCHas,MGS
k59_187598_2	857087.Metme_1472	1.13e-21	88.2	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XFS7@135618|Methylococcales	135618|Methylococcales	K	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
k59_187598_3	1049564.TevJSym_ao00450	1.74e-14	73.9	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1J4ZK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_72409_1	1165841.SULAR_00065	4.03e-112	327.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2YMV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0400	LYTB
k59_133703_1	203122.Sde_1119	4.4e-55	185.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,4656M@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrE	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_24931_2	1278073.MYSTI_03042	6.52e-23	102.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2YVI1@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_167182_1	314271.RB2654_19998	2.64e-08	59.3	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	degPch1	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_167182_2	1121104.AQXH01000002_gene569	1.79e-22	97.4	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,1IYDA@117747|Sphingobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_187602_1	566466.NOR53_1180	1.11e-63	210.0	COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1J8ZH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_106630_3	1312959.KI914682_gene2026	1.81e-05	47.8	COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria,1WAAH@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
k59_72412_1	395493.BegalDRAFT_2065	3.26e-05	55.1	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1QW47@1224|Proteobacteria,1RQU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
k59_92941_1	1089551.KE386572_gene1010	7.9e-48	173.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,4BQCA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	KL	COG0553 Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
k59_187603_1	1168289.AJKI01000031_gene931	2.61e-45	164.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_187603_2	1395571.TMS3_0123535	3.35e-07	50.8	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,1S1F0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k59_58968_1	768671.ThimaDRAFT_2108	1.41e-55	188.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,1WYGD@135613|Chromatiales	135613|Chromatiales	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_45219_1	439235.Dalk_0818	2.67e-98	293.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MJ7T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_167186_1	754436.JCM19237_5134	2.43e-20	90.9	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,1Y2PS@135623|Vibrionales	135623|Vibrionales	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_31851_1	2340.JV46_04260	1.62e-58	190.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,1J535@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_52125_1	2340.JV46_16160	3.96e-89	262.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1J5SI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_52125_2	305900.GV64_23265	5.79e-61	193.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1XH9B@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_208151_1	105559.Nwat_1703	1.53e-79	256.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1WVYF@135613|Chromatiales	135613|Chromatiales	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_86199_1	49964.Q94MS1_9CAUD	6.79e-51	171.0	4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses  no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_18364_1	28229.ND2E_2839	2.78e-71	236.0	COG0265@1|root,COG0265@2|Bacteria,1MWCG@1224|Proteobacteria	1224|Proteobacteria	O	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
k59_153847_1	1265313.HRUBRA_01119	3.83e-88	269.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_79169_1	1469245.JFBG01000023_gene1284	7.62e-65	219.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_201222_1	1168034.FH5T_08890	3.64e-88	267.0	2C793@1|root,2Z9MK@2|Bacteria,4NI6K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_38130_1	3641.EOY05821	1.83e-11	68.2	KOG1075@1|root,KOG1075@2759|Eukaryota,37ZQ4@33090|Viridiplantae,3GK8S@35493|Streptophyta	35493|Streptophyta	S	Domain of unknown function (DUF4283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,zf-CCHC_4
k59_112753_1	1396418.BATQ01000103_gene5522	2.75e-135	403.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_106643_1	1168034.FH5T_08780	1.03e-89	273.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,2FPCQ@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_79176_1	2340.JV46_06570	1.42e-95	301.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_92956_2	908612.HMPREF9720_0064	2.45e-34	130.0	COG4231@1|root,COG4231@2|Bacteria,4NJM1@976|Bacteroidetes,2FMYS@200643|Bacteroidia,22V15@171550|Rikenellaceae	976|Bacteroidetes	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR_N,TPP_enzyme_C
k59_52134_1	1244528.CFT03427_0185	2.37e-09	62.8	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_120094_1	557393.B8QTP9_9CAUD	6.3e-06	50.1	4QFRX@10239|Viruses,4QWQF@35237|dsDNA viruses  no RNA stage,4QUAP@28883|Caudovirales,4QJCG@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_157097_1	1408310.JHUW01000013_gene290	1.88e-39	147.0	COG0702@1|root,COG0702@2|Bacteria,4PNT7@976|Bacteroidetes,2G0XS@200643|Bacteroidia	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_116571_1	1122176.KB903554_gene3870	1.74e-17	83.2	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_116571_2	1242864.D187_010202	7.72e-31	117.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,42QN8@68525|delta/epsilon subdivisions,2WM0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
k59_170684_1	1049564.TevJSym_ah00230	2.17e-85	265.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1J4R1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
k59_1245_2	2340.JV46_18960	3.29e-23	100.0	COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1JB3D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	gspL	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
k59_82646_1	330084.JNYZ01000003_gene2353	8.12e-57	190.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4DXH9@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32,HTH_33
k59_75689_2	1449350.OCH239_07850	1.9e-06	54.7	COG1309@1|root,COG1309@2|Bacteria,1ND64@1224|Proteobacteria,2TTVA@28211|Alphaproteobacteria,4KMHM@93682|Roseivivax	28211|Alphaproteobacteria	K	Transcriptional regulator	rutR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
k59_163859_1	1504981.KO116_3261	2.8e-64	197.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	The gene assignment is based on its position in a multicopy insertion sequence, directly adjacent to an ORF matching an HMM for the IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_204542_1	41431.PCC8801_1889	5.1e-26	99.8	COG4634@1|root,COG4634@2|Bacteria,1GJHA@1117|Cyanobacteria,3KIYR@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_204542_2	1128427.KB904821_gene1605	2.84e-23	90.9	COG2442@1|root,COG2442@2|Bacteria,1G8A6@1117|Cyanobacteria,1HHJC@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
k59_129958_1	566466.NOR53_2066	2.76e-24	101.0	2DV0F@1|root,33TCS@2|Bacteria,1NSNY@1224|Proteobacteria,1SKXY@1236|Gammaproteobacteria,1J9F5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109683_1	118173.KB235914_gene2071	1.29e-30	110.0	COG2963@1|root,COG2963@2|Bacteria,1GAAT@1117|Cyanobacteria,1HGRD@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_109683_2	1397528.Q671_09500	1.5e-113	335.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_62278_1	1168034.FH5T_15445	2.77e-98	298.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,2FMP4@200643|Bacteroidia	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_191090_1	387093.SUN_1363	3.95e-150	448.0	COG1752@1|root,COG1752@2|Bacteria,1NCAA@1224|Proteobacteria,430CE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_55503_1	443152.MDG893_14243	1.53e-33	118.0	COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,1SEAC@1236|Gammaproteobacteria,46CX7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Helix-turn-helix domain	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_55503_2	1121937.AUHJ01000048_gene1211	2.47e-43	150.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,46ABE@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DDE domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_62282_1	1168034.FH5T_10410	2.94e-80	265.0	COG0841@1|root,COG1131@1|root,COG0841@2|Bacteria,COG1131@2|Bacteria,4NF8M@976|Bacteroidetes,2FQY7@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ACR_tran
k59_14849_1	756067.MicvaDRAFT_1141	2.6e-32	129.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
k59_197896_1	1382230.ASAP_0190	1.04e-18	90.1	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2JQ62@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_129967_1	1239962.C943_02115	4.1e-17	79.0	COG3015@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3187@2|Bacteria,4NSEQ@976|Bacteroidetes,47SMJ@768503|Cytophagia	976|Bacteroidetes	MP	NlpE N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	META,NlpE
k59_75698_1	1168034.FH5T_11520	4.79e-68	214.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,2FP5P@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_75698_2	1168034.FH5T_11525	5.55e-31	115.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,2FMH1@200643|Bacteroidia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_55518_1	1121937.AUHJ01000002_gene3434	1.11e-60	197.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,46AVD@72275|Alteromonadaceae	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_96174_1	1165841.SULAR_04207	1.35e-45	155.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2,CW_binding_1,DUF5011,PG_binding_1,YkuD
k59_96174_2	1165841.SULAR_04202	7.5e-73	223.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,42VAD@68525|delta/epsilon subdivisions,2YPP1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,TehB
k59_204563_1	1255043.TVNIR_2014	3.91e-54	184.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_21563_1	224911.27356272	7.18e-49	176.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,3JVPM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_136767_1	1286093.C266_10129	1.62e-25	105.0	COG4521@1|root,COG4521@2|Bacteria,1MVH2@1224|Proteobacteria,2VINJ@28216|Betaproteobacteria,1JZVK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	taurine ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
k59_75700_1	1165841.SULAR_07815	5.76e-102	299.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_129974_1	1541065.JRFE01000036_gene6503	2.61e-51	166.0	COG3415@1|root,COG3415@2|Bacteria,1GK71@1117|Cyanobacteria,3VNE9@52604|Pleurocapsales	1117|Cyanobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184207_1	1185876.BN8_01576	2.03e-05	48.1	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,47KRY@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_184207_2	1049564.TevJSym_ax00490	3.47e-31	122.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_150387_1	1121875.KB907555_gene376	1.13e-65	223.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75708_1	622637.KE124774_gene2771	4.93e-32	122.0	COG5501@1|root,COG5501@2|Bacteria,1PB0I@1224|Proteobacteria,2TR7M@28211|Alphaproteobacteria,36ZKC@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Sulfur oxidation protein SoxY	MA20_34470	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
k59_211551_1	291112.PAU_00108	5.72e-75	247.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	oligopeptidase	prlC	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_96192_1	2340.JV46_09630	1.16e-10	62.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_96192_2	765911.Thivi_4247	3.05e-43	154.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1SB6M@1236|Gammaproteobacteria,1X0V1@135613|Chromatiales	135613|Chromatiales	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_170728_1	1121875.KB907546_gene2208	9.36e-85	263.0	COG1680@1|root,COG1680@2|Bacteria,4PI69@976|Bacteroidetes,1I0GH@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_204589_2	765912.Thimo_2418	1.03e-14	72.8	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1WXW3@135613|Chromatiales	135613|Chromatiales	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_1306_1	572480.Arnit_0213	1.08e-63	201.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2YM7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
k59_62325_1	661478.OP10G_4644	5.61e-51	183.0	COG0058@1|root,COG0058@2|Bacteria	2|Bacteria	G	glycogen phosphorylase activity	-	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
k59_157160_1	2340.JV46_23420	8.26e-87	261.0	COG1376@1|root,COG1376@2|Bacteria,1R7VK@1224|Proteobacteria,1RZ5W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75719_1	517418.Ctha_1282	5.19e-33	127.0	COG4247@1|root,COG4247@2|Bacteria,1FEBY@1090|Chlorobi	1090|Chlorobi	I	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
k59_7965_1	1313421.JHBV01000041_gene3558	1.12e-56	181.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes	976|Bacteroidetes	K	gnat family	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_14882_1	2340.JV46_26630	1.3e-07	57.4	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,1RYAA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Pentapeptide repeat	-	-	-	ko:K18555	-	M00729	-	-	ko00000,ko00002,ko01504	-	-	-	DUF2169,Pentapeptide,Pentapeptide_4
k59_7967_1	1165841.SULAR_03322	1.32e-59	192.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_7967_2	1165841.SULAR_03327	7.88e-46	155.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_8324_1	237368.SCABRO_03590	3.29e-16	78.6	COG3696@1|root,COG3696@2|Bacteria,2IYCN@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_8324_2	237368.SCABRO_03591	4.99e-16	79.3	COG0845@1|root,COG0845@2|Bacteria,2IYDV@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_22003_1	749222.Nitsa_0755	5.37e-28	105.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42S15@68525|delta/epsilon subdivisions,2YT6B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_22003_2	1165841.SULAR_02698	2.82e-38	143.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2YRC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_171139_1	1121012.AUKX01000053_gene2559	1.05e-30	114.0	2CBAQ@1|root,32U2I@2|Bacteria,4NTIM@976|Bacteroidetes,1I3ZJ@117743|Flavobacteriia,23HJ6@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_171139_2	1121875.KB907549_gene1730	1.84e-17	82.0	COG1595@1|root,COG1595@2|Bacteria,4NGYM@976|Bacteroidetes,1I0GZ@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
k59_69462_1	471223.GWCH70_3187	1.35e-11	70.9	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1WE2R@129337|Geobacillus	91061|Bacilli	M	Ami_3	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
k59_83190_1	595460.RRSWK_01776	7.3e-08	60.8	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_2,TPR_8
k59_55926_1	313596.RB2501_06925	1.79e-73	221.0	2AMQ7@1|root,31CKD@2|Bacteria,4NQVK@976|Bacteroidetes,1I2S8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55926_2	743718.Isova_0755	9.54e-05	44.7	COG2153@1|root,COG2153@2|Bacteria,2IFAM@201174|Actinobacteria,4F52G@85017|Promicromonosporaceae	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k59_177807_1	1118054.CAGW01000063_gene2183	4.86e-39	142.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,26VCV@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter, ATP-binding protein	dppD	-	-	ko:K16202	ko02010,map02010	M00566	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.2	-	-	ABC_tran,oligo_HPY
k59_42299_1	886377.Murru_3244	4.69e-24	96.3	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1HXVV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_42299_2	143224.JQMD01000002_gene749	2.48e-42	151.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,1HYF9@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_69466_2	1165841.SULAR_03317	1.75e-83	269.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_201293_1	28229.ND2E_3821	6.36e-94	292.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,2Q7GQ@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_106756_2	867903.ThesuDRAFT_01105	5.64e-09	62.8	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
k59_140218_1	1165841.SULAR_04217	8.26e-88	268.0	COG0477@1|root,COG2814@2|Bacteria,1R7DW@1224|Proteobacteria,43BJI@68525|delta/epsilon subdivisions,2YT98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_140218_2	1165841.SULAR_04222	3.83e-07	50.1	COG0546@1|root,COG0546@2|Bacteria,1NDKE@1224|Proteobacteria,42SW4@68525|delta/epsilon subdivisions,2YPI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_25024_1	247634.GPB2148_3624	8.05e-122	372.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
k59_5082_1	953739.SVEN_7420	0.000534	48.1	COG3055@1|root,COG3055@2|Bacteria,2I91M@201174|Actinobacteria	201174|Actinobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
k59_167319_1	1165841.SULAR_03038	5.46e-101	298.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,42PD0@68525|delta/epsilon subdivisions,2YNP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_194698_1	1165841.SULAR_02268	1.93e-31	124.0	COG2200@1|root,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_120210_1	395493.BegalDRAFT_2876	5.9e-21	89.0	2EDW5@1|root,337RA@2|Bacteria,1N9KH@1224|Proteobacteria,1SDZH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k59_208260_1	1121272.KB903249_gene1816	4.47e-07	57.0	COG3033@1|root,COG3033@2|Bacteria,2GKH3@201174|Actinobacteria,4DI4T@85008|Micromonosporales	201174|Actinobacteria	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_59064_1	237727.NAP1_14638	1.55e-40	155.0	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,2TW3Y@28211|Alphaproteobacteria,2KEA5@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_18463_1	1121904.ARBP01000023_gene5047	0.000343	49.3	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47JJ5@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_99821_1	55952.BU52_17025	1.44e-10	68.2	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
k59_201315_1	313596.RB2501_08940	5.01e-132	380.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia	976|Bacteroidetes	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_38238_1	388413.ALPR1_11965	3.23e-129	388.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47TP1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_140229_1	768710.DesyoDRAFT_0565	3.09e-52	179.0	COG2199@1|root,COG3706@2|Bacteria,1V469@1239|Firmicutes,25BDA@186801|Clostridia,2625Y@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PilJ
k59_72586_1	313596.RB2501_09380	1.82e-79	241.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1HXWI@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_11438_1	1001530.BACE01000022_gene3634	2.42e-23	103.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XV3U@135623|Vibrionales	135623|Vibrionales	M	Biotin-lipoyl like	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_99827_1	472759.Nhal_1520	3.1e-34	134.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1WZX0@135613|Chromatiales	135613|Chromatiales	Q	PFAM multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
k59_86284_1	765420.OSCT_2325	1.66e-29	120.0	2C8CV@1|root,2Z8NV@2|Bacteria,2GB29@200795|Chloroflexi,376SN@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3095)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3095
k59_167339_1	870187.Thini_4336	2.41e-43	159.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RS9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
k59_208270_1	395493.BegalDRAFT_3501	6.08e-16	82.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9
k59_208270_2	395493.BegalDRAFT_1552	5.76e-25	97.4	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,462RB@72273|Thiotrichales	72273|Thiotrichales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_201323_2	1469245.JFBG01000010_gene614	2.73e-08	55.5	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWSZ@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_72590_1	927658.AJUM01000034_gene203	1.69e-65	212.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,2G0M8@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_72590_2	1165841.SULAR_09584	1.7e-25	98.2	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_99836_1	314282.PCNPT3_07310	3.58e-17	78.6	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria,2QISU@267894|Psychromonadaceae	1236|Gammaproteobacteria	C	Nitroreductase family	nfnB	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_140230_3	589865.DaAHT2_2431	2.94e-138	412.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MPFP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_133865_1	1165841.SULAR_10289	7.5e-08	52.8	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2YN2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_160794_1	3656.XP_008460615.1	0.0	1158.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RRH@33090|Viridiplantae,3G8MV@35493|Streptophyta,4JM10@91835|fabids	35493|Streptophyta	H	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Chromo,RVT_1,Retrotrans_gag,gag-asp_proteas,rve
k59_59077_1	340.xcc-b100_1709	9.72e-39	147.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1X313@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_167353_1	927658.AJUM01000037_gene2283	1.24e-18	83.6	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,3XIMI@558415|Marinilabiliaceae	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_167353_2	1168034.FH5T_06225	7.92e-46	155.0	COG0652@1|root,COG0652@2|Bacteria,4NI3Q@976|Bacteroidetes,2FQYV@200643|Bacteroidia	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_106807_1	395493.BegalDRAFT_1488	2.65e-62	203.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,460NT@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k59_160796_1	3988.XP_002535312.1	3.22e-140	414.0	COG0197@1|root,KOG3422@2759|Eukaryota,38965@33090|Viridiplantae,3GY34@35493|Streptophyta,4JV2J@91835|fabids	35493|Streptophyta	J	RIBOSOMAL protein	-	-	-	ko:K02878,ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16,Ribosomal_S3_C
k59_93093_2	2340.JV46_27870	1.5e-111	325.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1J5PX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
k59_25056_1	335284.Pcryo_1777	3.56e-53	187.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,3NIYQ@468|Moraxellaceae	1236|Gammaproteobacteria	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
k59_201349_1	992406.RIA_1371	2.08e-18	79.3	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1I3XI@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_201349_2	1120985.AUMI01000015_gene1460	1.03e-14	75.5	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4H2K8@909932|Negativicutes	909932|Negativicutes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_86309_1	2340.JV46_10870	2.56e-214	617.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1J4DR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_126888_1	2340.JV46_14730	2.76e-43	152.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1J56S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_126888_2	1206777.B195_09881	3.48e-08	56.6	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1Z4PT@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	EH	4-amino-4-deoxychorismate lyase	pabC	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366	Aminotran_4
k59_45427_2	742767.HMPREF9456_00078	1.63e-40	142.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,22W13@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_45429_1	1385420.FRA_44c11310	7.28e-05	47.4	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,46154@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
k59_140250_1	378806.STAUR_4846	1.12e-38	149.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WNBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K13611	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_107184_1	387092.NIS_0652	4.53e-82	258.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42NR1@68525|delta/epsilon subdivisions,2YMG6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the succinate malate CoA ligase beta subunit family	-	-	2.3.3.8	ko:K15231	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Citrate_bind
k59_134223_1	1232410.KI421420_gene3228	7.82e-23	100.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,43SP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_45886_1	1168034.FH5T_20720	4.14e-47	153.0	COG2801@1|root,COG2801@2|Bacteria,4P7NB@976|Bacteroidetes,2FZNI@200643|Bacteroidia	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve_3
k59_167875_1	313595.P700755_001830	2.6e-34	130.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1HWUY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
k59_167875_2	865937.Gilli_3466	4.08e-16	76.3	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1HXJT@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
k59_127293_1	163908.KB235896_gene4069	2.52e-40	151.0	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_9
k59_140643_1	1165841.SULAR_10119	7.07e-79	241.0	COG3705@1|root,COG3705@2|Bacteria,1QV6Q@1224|Proteobacteria,43BNS@68525|delta/epsilon subdivisions,2YT9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
k59_140643_2	1165841.SULAR_10124	1.65e-68	217.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2YN1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_120676_1	1123269.NX02_05540	7e-79	251.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2K04K@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_195082_1	909663.KI867150_gene1309	4.75e-07	52.0	COG2801@1|root,COG2801@2|Bacteria,1R6TH@1224|Proteobacteria,42VCD@68525|delta/epsilon subdivisions,2WRUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
k59_195082_2	909663.KI867150_gene1310	1.07e-24	102.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,42Y9C@68525|delta/epsilon subdivisions,2WUJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_79787_1	1165841.SULAR_00170	5.78e-14	65.9	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,42VKI@68525|delta/epsilon subdivisions,2YQD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
k59_79787_2	1165841.SULAR_00165	7.38e-193	536.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2YMZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_79787_3	1165841.SULAR_00160	3.81e-06	47.8	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_195093_1	1123318.KB904595_gene1701	2.21e-09	58.2	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_154248_1	1165841.SULAR_03267	3.96e-15	72.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2YMH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_154248_2	472759.Nhal_3098	2.46e-37	139.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_147711_1	582899.Hden_0696	1.81e-19	82.8	COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,2UAPN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glycine cleavage H-protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_215060_1	870187.Thini_0497	4.25e-46	151.0	COG2337@1|root,COG2337@2|Bacteria,1MYU1@1224|Proteobacteria,1SI9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
k59_215060_2	697282.Mettu_0483	0.000236	43.1	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,1TGY7@1236|Gammaproteobacteria,1XG5C@135618|Methylococcales	135618|Methylococcales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_201871_1	765912.Thimo_1333	1.78e-69	221.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1WVWC@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM RNA polymerase sigma factor RpoS	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_127297_1	1168034.FH5T_05700	1.43e-11	63.9	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,2FN92@200643|Bacteroidia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_69432_2	2340.JV46_24150	1.93e-35	122.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1J6U6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_69432_3	1537715.JQFJ01000002_gene803	2.03e-10	64.7	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,2JZWN@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_76101_1	1004149.AFOE01000033_gene720	2.48e-49	171.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1I0C6@117743|Flavobacteriia	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
k59_76101_2	1121875.KB907550_gene668	1.28e-23	98.6	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1HYER@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_28910_1	1279019.ARQK01000061_gene1854	1.69e-52	183.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1WXXX@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_164296_2	1045004.OKIT_1540	8.94e-29	108.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,4AXV8@81850|Leuconostocaceae	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_123603_1	75379.Tint_2201	4.49e-33	131.0	COG3843@1|root,COG3843@2|Bacteria	2|Bacteria	U	relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
k59_171113_1	386415.NT01CX_0007	2.72e-14	73.2	COG3963@1|root,COG3963@2|Bacteria,1V2ZK@1239|Firmicutes,24IUQ@186801|Clostridia,36HY6@31979|Clostridiaceae	186801|Clostridia	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	RrnaAD
k59_83165_1	797299.HALLA_16155	1.52e-06	56.2	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,23SV0@183963|Halobacteria	183963|Halobacteria	L	exporters of the RND superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_62759_1	1254432.SCE1572_15570	9.93e-12	68.9	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
k59_62759_2	1208321.D104_12620	3.34e-16	76.3	COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,1XJ9T@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_1716_1	1209072.ALBT01000031_gene1829	7.97e-13	72.4	COG3866@1|root,COG4677@1|root,COG5276@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,COG5276@2|Bacteria,1QPFF@1224|Proteobacteria,1T5VI@1236|Gammaproteobacteria,1FFY2@10|Cellvibrio	1236|Gammaproteobacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
k59_143794_1	686340.Metal_1114	7.94e-88	266.0	COG5464@1|root,COG5464@2|Bacteria,1R8FS@1224|Proteobacteria,1SC36@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
k59_8307_1	545694.TREPR_2598	3.32e-10	63.2	COG0544@1|root,COG0544@2|Bacteria,2J5FS@203691|Spirochaetes	203691|Spirochaetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_177783_1	1165841.SULAR_00280	1.76e-124	367.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_96593_1	1165841.SULAR_09279	3.76e-56	189.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42Q9B@68525|delta/epsilon subdivisions,2YNKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_164305_1	887062.HGR_15414	8.24e-65	207.0	COG1309@1|root,COG1309@2|Bacteria,1R5AI@1224|Proteobacteria,2VH3Y@28216|Betaproteobacteria,4ABHB@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_9,TetR_N
k59_137191_1	745411.B3C1_17662	2.07e-48	164.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1J68Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_137191_2	1238190.AMQY01000023_gene267	1.56e-20	89.4	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k59_83176_1	945713.IALB_0655	1.57e-31	122.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	CP_0468	-	-	ko:K03308,ko:K03466	-	-	-	-	ko00000,ko03036	2.A.22.4,2.A.22.5,3.A.12	-	-	SNF
k59_171124_1	1335757.SPICUR_07685	1.85e-35	129.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1WWCD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_117048_1	519989.ECTPHS_04418	5.68e-34	130.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1WW2P@135613|Chromatiales	135613|Chromatiales	D	Reduces the stability of FtsZ polymers in the presence of ATP	zapE	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
k59_184633_1	3702.ATMG00520.1	2.61e-143	422.0	COG3344@1|root,KOG4768@2759|Eukaryota,37KUX@33090|Viridiplantae,3GHBI@35493|Streptophyta,3HZNG@3699|Brassicales	35493|Streptophyta	A	Intron maturase, type II family protein	matR	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2
k59_55911_1	387093.SUN_0406	8.66e-48	160.0	COG4461@1|root,COG4461@2|Bacteria,1PFFH@1224|Proteobacteria,43ABM@68525|delta/epsilon subdivisions,2YR0C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
k59_89896_1	1120999.JONM01000002_gene767	6.44e-19	90.5	COG0277@1|root,COG4798@1|root,COG0277@2|Bacteria,COG4798@2|Bacteria,1MV1Q@1224|Proteobacteria,2VI37@28216|Betaproteobacteria,2KS9Z@206351|Neisseriales	206351|Neisseriales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
k59_157598_1	1165841.SULAR_00565	1.68e-79	250.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42Z72@68525|delta/epsilon subdivisions,2YRGJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_164321_1	1165841.SULAR_01958	2.01e-82	258.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_211882_1	1121930.AQXG01000001_gene1102	5.3e-15	79.7	COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_191523_1	379066.GAU_1197	1.75e-11	63.2	COG1595@1|root,COG1595@2|Bacteria,1ZV2F@142182|Gemmatimonadetes	2|Bacteria	K	ECF sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
k59_28932_1	1165841.SULAR_03887	2.06e-36	123.0	2AN4M@1|root,31D2D@2|Bacteria,1QA3X@1224|Proteobacteria,433I5@68525|delta/epsilon subdivisions,2YSM0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_28932_2	929558.SMGD1_0338	1.48e-29	105.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2YPX8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Cold-shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_69449_1	1165841.SULAR_09409	7.87e-49	164.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2YMM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_69449_2	1165841.SULAR_09414	1.07e-106	322.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2YM9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_143829_1	2340.JV46_11690	6.93e-121	365.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1J4H9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	iJN746.PP_5217	PP_kinase,PP_kinase_C,PP_kinase_N
k59_184650_1	1173027.Mic7113_1194	1.06e-40	155.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,Pkinase,Response_reg
k59_76146_1	1121875.KB907546_gene2208	3.06e-135	396.0	COG1680@1|root,COG1680@2|Bacteria,4PI69@976|Bacteroidetes,1I0GH@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_164328_1	1165841.SULAR_07795	8.62e-13	67.4	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_164328_2	1165841.SULAR_07800	3.53e-61	199.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,42VG8@68525|delta/epsilon subdivisions,2YR2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
k59_28934_1	556267.HWAG_00816	4.8e-18	88.2	COG5362@1|root,COG5362@2|Bacteria,1N1KT@1224|Proteobacteria,42N35@68525|delta/epsilon subdivisions,2YN75@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TIGRFAM Phage	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55921_1	1144275.COCOR_07019	6.36e-93	297.0	COG1960@1|root,COG1960@2|Bacteria,1RIW2@1224|Proteobacteria	1224|Proteobacteria	I	Acyl-CoA oxidase	-	-	1.3.3.6	ko:K00232	ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146	M00087,M00113	R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_157617_1	1122614.JHZF01000013_gene3129	2.65e-32	131.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_9,TarH
k59_63215_1	1244083.CSUNSWCD_2364	1.12e-24	101.0	28HH1@1|root,2Z7SS@2|Bacteria,1NB2F@1224|Proteobacteria,42ZFT@68525|delta/epsilon subdivisions,2YRRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63215_2	1163617.SCD_n02931	2.04e-09	57.8	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_56282_1	1121405.dsmv_1256	1.33e-17	80.5	COG2197@1|root,COG2197@2|Bacteria,1R3YQ@1224|Proteobacteria,42N0Q@68525|delta/epsilon subdivisions,2WM6W@28221|Deltaproteobacteria,2MIJG@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_4,PAS_9
k59_56282_2	1121405.dsmv_3248	5.37e-20	88.2	28PNF@1|root,2ZCB7@2|Bacteria,1RA6N@1224|Proteobacteria,42RBI@68525|delta/epsilon subdivisions,2WN4P@28221|Deltaproteobacteria,2MJHU@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_69877_2	390235.PputW619_1257	4.79e-20	91.3	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1YWXN@136845|Pseudomonas putida group	1236|Gammaproteobacteria	L	May be involved in recombination	rdgC	GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009295,GO:0019219,GO:0019222,GO:0031323,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k59_22488_2	1056820.KB900665_gene2870	2.95e-11	67.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,2PNKN@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	U	haemagglutination activity domain	rscA	-	-	-	-	-	-	-	-	-	-	-	DUF3739,ESPR,Haemagg_act,PATR
k59_103877_1	1165841.SULAR_08879	1.07e-84	265.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2YS4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
k59_103877_2	387093.SUN_0515	1.31e-37	136.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2YMJJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	malic enzyme	mez	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_191954_1	1408473.JHXO01000006_gene1027	1.47e-70	219.0	COG0664@1|root,COG0664@2|Bacteria,4P3ES@976|Bacteroidetes	976|Bacteroidetes	T	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_124122_1	1004785.AMBLS11_18400	2.02e-80	261.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,464NC@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG2183 Transcriptional accessory protein	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_110576_1	443144.GM21_1745	1.12e-112	330.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WIPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_158133_1	1336233.JAEH01000023_gene1900	7.3e-12	74.7	COG2202@1|root,COG3292@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3292@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q9C5@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_8,PAS_9
k59_97130_1	1165841.SULAR_06783	3.07e-63	196.0	COG1214@1|root,COG1214@2|Bacteria,1Q1J6@1224|Proteobacteria,42TUF@68525|delta/epsilon subdivisions,2YQ3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_97130_2	1165841.SULAR_06788	1.54e-39	138.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2YMMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_151206_1	402777.KB235898_gene5045	3.62e-52	187.0	COG4251@1|root,COG5001@1|root,COG4251@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GAF,GAF_2,GGDEF,PAS_3,PAS_9,PHY
k59_83623_1	1168034.FH5T_05020	5.22e-68	229.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
k59_124133_1	1380394.JADL01000010_gene4277	4.04e-94	296.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,2TSSM@28211|Alphaproteobacteria,2JR62@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
k59_97134_1	1177181.T9A_02810	2.44e-10	61.6	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,1S1AU@1236|Gammaproteobacteria,1XR3J@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_97134_2	489825.LYNGBM3L_40520	1e-25	107.0	28HH1@1|root,2Z7SS@2|Bacteria,1G3TR@1117|Cyanobacteria,1H8R1@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_29326_1	283942.IL1312	8.7e-71	228.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,2QFE1@267893|Idiomarinaceae	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_124134_1	857087.Metme_3206	1.6e-36	142.0	COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1XG26@135618|Methylococcales	135618|Methylococcales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_2237_1	1165841.SULAR_04382	4.49e-91	269.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2YQ20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EJ	GlutRNAGln amidotransferase subunit D	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_35941_1	745718.JADT01000001_gene1800	4.21e-12	65.1	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1HY38@117743|Flavobacteriia	976|Bacteroidetes	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_42678_2	879212.DespoDRAFT_00640	2.12e-30	113.0	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria,2MMAB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124136_2	98439.AJLL01000075_gene887	8.66e-11	57.8	2AGP1@1|root,316WK@2|Bacteria,1GKU8@1117|Cyanobacteria,1JMR8@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_185098_1	4513.MLOC_62325.1	1.29e-21	95.9	COG5429@1|root,2QQGJ@2759|Eukaryota,37NT0@33090|Viridiplantae,3GAAC@35493|Streptophyta,3KQ82@4447|Liliopsida,3IC5C@38820|Poales	35493|Streptophyta	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
k59_207110_1	1168034.FH5T_16520	1.57e-69	224.0	COG3547@1|root,COG3547@2|Bacteria,4NHYP@976|Bacteroidetes,2FKYS@200643|Bacteroidia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_166214_1	318161.Sden_2282	7.28e-32	122.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,2QBUG@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0502 family	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k59_186606_1	592015.HMPREF1705_01710	2.23e-14	68.2	COG1942@1|root,COG1942@2|Bacteria	2|Bacteria	S	isomerase activity	MA20_05500	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_186606_2	1042877.GQS_04165	5.46e-10	56.6	arCOG02240@1|root,arCOG02240@2157|Archaea,2Y0KC@28890|Euryarchaeota,244PY@183968|Thermococci	183968|Thermococci	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_159566_1	1123237.Salmuc_04623	1.12e-15	79.0	COG1674@1|root,COG2319@1|root,COG1674@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2U3AU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_152838_1	1165841.SULAR_09379	2.52e-107	312.0	2AIWB@1|root,319DT@2|Bacteria,1Q2F3@1224|Proteobacteria,42VJD@68525|delta/epsilon subdivisions,2YQCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111953_1	396588.Tgr7_1531	5.69e-76	241.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_85175_1	2340.JV46_15380	1.64e-15	75.5	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	dsrS	-	-	-	-	-	-	-	-	-	-	-	-
k59_85175_2	631362.Thi970DRAFT_00868	5.51e-82	251.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1WWMV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_139151_1	1120956.JHZK01000042_gene3049	2.25e-108	319.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,2TV8A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Protein of unknown function (DUF1254)	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	DUF1214,DUF1254
k59_105452_1	1268622.AVS7_00055	1.93e-16	82.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VNK7@28216|Betaproteobacteria,4AA8Z@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_57859_1	1283300.ATXB01000002_gene2597	2.24e-47	163.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,1XF1M@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_132576_1	1165841.SULAR_01638	2.75e-25	97.8	28QM5@1|root,3192M@2|Bacteria,1Q1JK@1224|Proteobacteria,42TV6@68525|delta/epsilon subdivisions,2YPT2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132576_2	1165841.SULAR_01638	1.86e-53	169.0	28QM5@1|root,3192M@2|Bacteria,1Q1JK@1224|Proteobacteria,42TV6@68525|delta/epsilon subdivisions,2YPT2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119196_1	1121353.H924_07255	5.82e-15	80.5	COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria,22MAR@1653|Corynebacteriaceae	201174|Actinobacteria	KL	Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	SNF2_N
k59_23927_1	643867.Ftrac_2983	7.45e-08	64.7	COG1361@1|root,COG2931@1|root,COG3391@1|root,COG3420@1|root,COG3468@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,47Y61@768503|Cytophagia	976|Bacteroidetes	MN	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
k59_98775_1	395961.Cyan7425_2304	2.77e-11	64.3	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1G1M0@1117|Cyanobacteria,3KG4Q@43988|Cyanothece	1117|Cyanobacteria	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_98775_2	1165841.SULAR_01460	1.77e-68	219.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2YNK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_3819_1	2340.JV46_24720	1.3e-50	163.0	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,1JAGD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	soxX	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_3819_2	1123514.KB905899_gene554	3.09e-07	50.4	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,463KC@72273|Thiotrichales	72273|Thiotrichales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,TAT_signal
k59_111955_1	1165841.SULAR_01883	2.16e-66	206.0	COG4276@1|root,COG4276@2|Bacteria,1N2Z3@1224|Proteobacteria,42THP@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_105458_1	666686.B1NLA3E_00845	1.06e-28	109.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,4HH7M@91061|Bacilli,1ZHKI@1386|Bacillus	91061|Bacilli	S	GyrI-like small molecule binding domain	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	GyrI-like
k59_30905_2	1273707.L7TJP4_9CAUD	7.98e-25	105.0	4QCM6@10239|Viruses,4QVAQ@35237|dsDNA viruses  no RNA stage,4QPVV@28883|Caudovirales,4QNID@10744|Podoviridae	10744|Podoviridae	S	actin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_17191_1	631362.Thi970DRAFT_03499	1.52e-74	231.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1WWCV@135613|Chromatiales	135613|Chromatiales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_10389_1	387093.SUN_0530	6.26e-68	211.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0000287,GO:0003674,GO:0003824,GO:0004789,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00788,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4300,iSSON_1240.SSON_4166	TMP-TENI
k59_10389_2	1165841.SULAR_08789	5.41e-16	75.1	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2YMUY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_57871_1	338963.Pcar_0428	2.43e-24	107.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2WQTT@28221|Deltaproteobacteria,43VJV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_207126_1	1192034.CAP_4580	1.99e-21	102.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1MX27@1224|Proteobacteria	1224|Proteobacteria	TV	ABC-type multidrug transport system ATPase component	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
k59_71389_2	1122207.MUS1_09105	6.45e-11	67.8	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XIFS@135619|Oceanospirillales	135619|Oceanospirillales	CI	Oxaloacetate decarboxylase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_37279_1	1334046.AYTB01000008_gene2521	1.03e-64	214.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,26EKB@186818|Planococcaceae	91061|Bacilli	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_3827_1	387093.SUN_0559	3.38e-27	115.0	COG3439@1|root,COG3439@2|Bacteria,1PWY7@1224|Proteobacteria,42Y9J@68525|delta/epsilon subdivisions,2YRF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_51083_1	313596.RB2501_07625	2.3e-61	205.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44088_1	314285.KT71_08620	1.01e-87	268.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1J9WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_98791_1	754477.Q7C_1650	2.27e-88	272.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,4606R@72273|Thiotrichales	72273|Thiotrichales	L	ATPase (AAA	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_105466_1	1165841.SULAR_10409	4.78e-210	585.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2YMZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_57877_1	40373.F991_03112	1.18e-08	62.4	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,3NKHS@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
k59_139173_1	261292.Nit79A3_3476	2.17e-32	125.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,371TQ@32003|Nitrosomonadales	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_139173_2	1408444.JHYC01000014_gene2318	2.19e-05	47.8	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1JC9J@118969|Legionellales	118969|Legionellales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_23947_1	1165841.SULAR_01360	9.21e-132	402.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_179651_1	1288826.MSNKSG1_00546	7.79e-42	139.0	2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
k59_179651_2	1415778.JQMM01000001_gene2176	2.14e-27	103.0	COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	epsilon subunit	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k59_111973_1	1165841.SULAR_09669	4.11e-123	358.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_71402_1	2340.JV46_18890	3.19e-35	131.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1J7ED@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG1459 Type II secretory pathway, component PulF	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_71402_2	561230.PC1_2857	9.96e-32	117.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1MQU6@122277|Pectobacterium	1236|Gammaproteobacteria	U	General secretion pathway protein	gspG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_207148_1	713586.KB900536_gene2831	1.26e-15	76.3	28JUY@1|root,2Z9JY@2|Bacteria,1R822@1224|Proteobacteria,1RPY0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105478_1	1122619.KB892341_gene785	3.34e-92	291.0	COG3012@1|root,COG3012@2|Bacteria,1R5E5@1224|Proteobacteria,2VZMD@28216|Betaproteobacteria,3T744@506|Alcaligenaceae	28216|Betaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,SEC-C
k59_186640_2	1165841.SULAR_05503	4.4e-82	251.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2YN5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_152869_1	377629.TERTU_0024	3.59e-35	124.0	2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,2PQD7@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152869_2	83406.HDN1F_27770	8.66e-05	45.4	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1J4MZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
k59_91854_1	247490.KSU1_C0343	3.69e-32	131.0	COG1404@1|root,COG3534@1|root,COG1404@2|Bacteria,COG3534@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
k59_139188_1	568816.Acin_0985	2.43e-71	226.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4H1YG@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_37298_1	313596.RB2501_09320	1.39e-68	234.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD,Sortilin-Vps10,TSP_3
k59_179657_1	395493.BegalDRAFT_0091	1.01e-61	208.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_91859_1	313596.RB2501_01555	3.6e-120	361.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1HYUH@117743|Flavobacteriia	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_30937_1	1236542.BALM01000026_gene1951	2.25e-83	252.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,1RNXB@1236|Gammaproteobacteria,2QB50@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Coenzyme A transferase	pcaI	-	2.8.3.5,2.8.3.6	ko:K01027,ko:K01031	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_152881_1	1379698.RBG1_1C00001G0607	8.23e-22	100.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
k59_125716_1	2340.JV46_16110	2.38e-140	433.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_179669_1	765914.ThisiDRAFT_1638	1.48e-44	155.0	COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1RY54@1236|Gammaproteobacteria,1WWFU@135613|Chromatiales	135613|Chromatiales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase
k59_64656_1	1274524.BSONL12_01837	3.11e-39	144.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus	91061|Bacilli	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_64656_2	99598.Cal7507_5929	1.73e-31	116.0	COG0512@1|root,COG0512@2|Bacteria,1G0QK@1117|Cyanobacteria,1HK1B@1161|Nostocales	1117|Cyanobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_207166_1	2340.JV46_17160	5.79e-139	410.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1J5M7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_213752_1	395493.BegalDRAFT_0114	2.92e-67	216.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,461W9@72273|Thiotrichales	72273|Thiotrichales	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_125719_1	555778.Hneap_0762	4.91e-23	100.0	COG1538@1|root,COG1538@2|Bacteria,1R7SQ@1224|Proteobacteria,1SN2C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_125719_2	1424334.W822_09630	4.61e-05	44.7	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,3T3JU@506|Alcaligenaceae	28216|Betaproteobacteria	Q	ABC transporter substrate-binding protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_71420_1	1165841.SULAR_02888	3.48e-64	197.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_71420_2	387093.SUN_0973	3.38e-39	142.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_166677_2	1191523.MROS_1799	4.09e-10	60.1	COG0283@1|root,COG0283@2|Bacteria	2|Bacteria	F	belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.19,2.7.4.25,6.3.2.1	ko:K00800,ko:K00945,ko:K03977,ko:K13799	ko00240,ko00400,ko00410,ko00770,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map00410,map00770,map01100,map01110,map01130,map01230	M00022,M00052,M00119	R00158,R00512,R01665,R02473,R03460	RC00002,RC00096,RC00141,RC00350	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Cytidylate_kin,Pantoate_ligase
k59_92370_1	323261.Noc_2083	4.73e-57	194.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,1RSFG@1236|Gammaproteobacteria,1WW9R@135613|Chromatiales	135613|Chromatiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k59_146650_1	348824.LPU83_4015	7.07e-49	171.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2TU9Q@28211|Alphaproteobacteria,4BDJD@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Phospholipase D. Active site motifs.	ymdC	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_19828_1	1004149.AFOE01000038_gene873	1.23e-85	261.0	COG3595@1|root,COG3595@2|Bacteria,4PMD5@976|Bacteroidetes,1IK6I@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
k59_87471_3	2340.JV46_02720	5.78e-42	153.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	2.7.11.1	ko:K03546,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko03400	-	-	-	AAA_23,Pkinase,SMC_N
k59_141558_1	765910.MARPU_07365	1.81e-33	125.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1X04E@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_216030_1	243233.MCA1276	9.15e-21	90.9	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1XE0C@135618|Methylococcales	135618|Methylococcales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_202685_1	1165841.SULAR_00405	3.43e-93	286.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_155181_1	1165841.SULAR_10014	5.2e-100	315.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_121501_2	376686.Fjoh_3893	2.36e-06	48.9	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1IIM8@117743|Flavobacteriia,2P0EE@237|Flavobacterium	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_114047_1	997346.HMPREF9374_0195	1.73e-14	72.8	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,27C4A@186824|Thermoactinomycetaceae	91061|Bacilli	L	RuvA, C-terminal domain	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_114047_2	880073.Calab_1909	1.05e-18	82.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
k59_175658_1	444861.E3SPK9_9CAUD	1.33e-59	203.0	4QAJ5@10239|Viruses,4QUS9@35237|dsDNA viruses  no RNA stage,4QPY5@28883|Caudovirales	28883|Caudovirales	S	Major capsid protein Gp23	-	GO:0005575,GO:0019012,GO:0019028,GO:0044423	-	-	-	-	-	-	-	-	-	-	-
k59_148678_1	1123400.KB904782_gene1366	9.29e-26	99.0	2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	type III effector	hopJ	-	-	-	-	-	-	-	-	-	-	-	HopJ
k59_148678_2	2340.JV46_05350	4.5e-38	132.0	COG3439@1|root,COG3439@2|Bacteria,1NDCV@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_53542_1	765912.Thimo_0545	3.65e-23	91.7	COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria,1WYQ6@135613|Chromatiales	135613|Chromatiales	P	Part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_128098_1	1168034.FH5T_04765	1.17e-73	228.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,2FNI4@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_128098_2	1168034.FH5T_04755	1.77e-17	81.6	COG1509@1|root,COG1509@2|Bacteria,4NK6C@976|Bacteroidetes,2FMW5@200643|Bacteroidia	976|Bacteroidetes	E	KamA family	eam	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	-
k59_195937_1	2340.JV46_08130	4.37e-79	250.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1J5DJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_175674_1	395493.BegalDRAFT_0440	3.85e-67	206.0	COG3255@1|root,COG3255@2|Bacteria,1RI49@1224|Proteobacteria,1S38T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26547_1	1074889.MADAR_394	7.86e-05	50.8	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia,3IVH9@39782|Blattabacteriaceae	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_60529_1	1165841.SULAR_08999	2.5e-47	155.0	COG1331@1|root,COG1331@2|Bacteria,1QZ2A@1224|Proteobacteria,43CEH@68525|delta/epsilon subdivisions,2YQRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_60529_2	1165841.SULAR_08994	2.38e-41	145.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_135006_2	870187.Thini_0477	2.26e-70	222.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k59_155211_1	907348.TresaDRAFT_2259	0.000409	48.9	COG3829@1|root,COG3829@2|Bacteria,2J63K@203691|Spirochaetes	203691|Spirochaetes	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_87504_1	159087.Daro_2223	2.96e-203	571.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,2VMP0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_73604_1	314285.KT71_04640	1.5e-89	278.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1J5CG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_135008_1	1056820.KB900674_gene2564	7.91e-16	73.2	2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,1S999@1236|Gammaproteobacteria,2PQG8@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Nitrogen fixation protein NifW	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_135008_2	765912.Thimo_3231	5.97e-50	162.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,1S6X5@1236|Gammaproteobacteria,1WY5W@135613|Chromatiales	135613|Chromatiales	O	PFAM NifZ	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k59_108168_1	1165841.SULAR_09894	1.12e-111	324.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_67374_1	269797.Mbar_A3057	2.27e-06	49.3	COG1513@1|root,arCOG01488@2157|Archaea,2XX3Y@28890|Euryarchaeota,2NA2H@224756|Methanomicrobia	224756|Methanomicrobia	F	MafB19-like deaminase	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_67374_2	1168034.FH5T_01495	2.39e-33	124.0	COG1595@1|root,COG2202@1|root,COG1595@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF4157,HATPase_c,PAS,PAS_3,PAS_9,SatD,Sigma70_r2
k59_182259_1	575540.Isop_1559	8.36e-25	107.0	COG0303@1|root,COG0303@2|Bacteria,2IY2T@203682|Planctomycetes	203682|Planctomycetes	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_94421_1	1123070.KB899249_gene350	7.89e-37	138.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_94421_2	398527.Bphyt_6672	7.19e-87	263.0	COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,2VV9Q@28216|Betaproteobacteria,1KHKU@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12904_1	1121396.KB893106_gene1818	4.26e-53	189.0	COG0823@1|root,COG4870@1|root,COG0823@2|Bacteria,COG4870@2|Bacteria,1R2H6@1224|Proteobacteria,42Y08@68525|delta/epsilon subdivisions,2WSRJ@28221|Deltaproteobacteria	2|Bacteria	U	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4214,LRR_5,Peptidase_C1,SLH
k59_162042_1	1165841.SULAR_00070	3.89e-84	259.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2YMG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_53571_1	179408.Osc7112_5096	8.31e-49	180.0	COG0515@1|root,COG0745@1|root,COG2203@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
k59_33366_1	136993.KB900626_gene1229	2.18e-73	228.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_141602_1	616991.JPOO01000003_gene2681	1.01e-26	115.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia,23FSS@178469|Arenibacter	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_10,TPR_12,TPR_7,TPR_8
k59_121520_1	1165841.SULAR_04132	9.11e-116	338.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_175718_2	1117318.PRUB_09054	2.34e-09	58.2	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,2Q0XI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3318	GDC-P
k59_114101_1	1173026.Glo7428_2548	3.3e-20	95.1	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_9
k59_87529_1	1029823.AFIE01000108_gene1157	1.34e-14	80.9	COG3209@1|root,COG3209@2|Bacteria,1NKN0@1224|Proteobacteria,1SIPX@1236|Gammaproteobacteria,3NS7M@468|Moraxellaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	-
k59_39670_1	1366050.N234_30445	2.66e-08	60.1	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K1T4@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_175722_2	1118054.CAGW01000017_gene4395	1.18e-123	363.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,26TCW@186822|Paenibacillaceae	91061|Bacilli	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_12931_1	387093.SUN_0004	4.17e-84	263.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_12931_2	1165841.SULAR_08492	5.72e-22	94.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2YMUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_169019_1	1340493.JNIF01000003_gene2732	5.14e-56	181.0	COG2096@1|root,COG2096@2|Bacteria,3Y83S@57723|Acidobacteria	57723|Acidobacteria	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
k59_216086_1	1415754.JQMK01000005_gene1767	2.84e-24	96.7	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_108193_1	445686.E3SL62_9CAUD	2.14e-26	112.0	4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses  no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage T4-like capsid assembly protein (Gp20)	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_60938_1	1168034.FH5T_08620	1.45e-87	263.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,2FM2S@200643|Bacteroidia	976|Bacteroidetes	S	Succinate dehydrogenase cytochrome B subunit, b558 family	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_87964_1	1250232.JQNJ01000001_gene809	1.48e-36	127.0	COG1452@1|root,COG1452@2|Bacteria,4PKIN@976|Bacteroidetes,1IJA7@117743|Flavobacteriia	976|Bacteroidetes	M	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	-	-	-	-	-	-	-	-	-	LptC
k59_87964_2	886377.Murru_0892	9.71e-23	89.0	2DQIW@1|root,33758@2|Bacteria,4NV6U@976|Bacteroidetes,1I5DB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_87964_3	1004149.AFOE01000018_gene612	1.47e-115	344.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_203185_1	998674.ATTE01000001_gene1670	4.49e-132	398.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,45ZUZ@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_60940_1	1304883.KI912532_gene1328	5.87e-20	93.2	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,2KVAI@206389|Rhodocyclales	206389|Rhodocyclales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
k59_209942_1	1395513.P343_04770	4.06e-34	127.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,26NY2@186821|Sporolactobacillaceae	91061|Bacilli	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_176068_1	509635.N824_21215	3.42e-35	135.0	COG3547@1|root,COG3547@2|Bacteria,4NGED@976|Bacteroidetes,1IQ9F@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_33737_1	1165841.SULAR_05533	2.51e-112	335.0	COG3203@1|root,COG3203@2|Bacteria,1QVBP@1224|Proteobacteria,42M72@68525|delta/epsilon subdivisions,2YNNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_173513_2	335543.Sfum_1617	4.33e-66	223.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_31419_1	224324.aq_906	5.81e-12	65.9	COG0704@1|root,COG0704@2|Bacteria,2G47N@200783|Aquificae	200783|Aquificae	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0060255,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_31419_2	1260251.SPISAL_06605	1.6e-51	170.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1X0E8@135613|Chromatiales	135613|Chromatiales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_58487_1	1165841.SULAR_01668	1.5e-71	228.0	COG2340@1|root,COG2340@2|Bacteria,1NAW3@1224|Proteobacteria,42PNS@68525|delta/epsilon subdivisions,2YN4B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
k59_214120_1	1218173.BALCAV_0206915	3.77e-28	117.0	COG0624@1|root,COG0624@2|Bacteria,1TPSM@1239|Firmicutes,4HD69@91061|Bacilli,1ZDSF@1386|Bacillus	91061|Bacilli	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_207716_2	765914.ThisiDRAFT_0673	1.19e-22	88.6	COG1145@1|root,COG1145@2|Bacteria,1N859@1224|Proteobacteria,1SEBQ@1236|Gammaproteobacteria,1X2U5@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_126239_1	566466.NOR53_3361	1.58e-16	78.6	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_126239_2	2340.JV46_29200	1.15e-41	144.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1J4GM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_207717_1	886377.Murru_2252	3.57e-33	115.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1I52P@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_207717_2	313590.MED134_00995	3.77e-22	87.8	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia,37F4R@326319|Dokdonia	976|Bacteroidetes	J	Ribosomal protein L20	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_119677_1	666685.R2APBS1_0864	6.14e-38	148.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales	135614|Xanthomonadales	T	Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_65204_1	246197.MXAN_3636	2.26e-30	124.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_146736_1	1408424.JHYI01000005_gene3228	2.09e-06	54.3	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,1ZBRZ@1386|Bacillus	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k59_92458_1	338966.Ppro_1770	3.39e-141	414.0	COG3385@1|root,COG3385@2|Bacteria,1REZ3@1224|Proteobacteria,42RPA@68525|delta/epsilon subdivisions,2WNFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_126251_1	357808.RoseRS_0444	4.87e-28	114.0	COG3385@1|root,COG3385@2|Bacteria,2G9A6@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_37753_1	1122176.KB903564_gene3174	1.84e-14	70.9	COG1573@1|root,COG1573@2|Bacteria,4NG84@976|Bacteroidetes,1IXA2@117747|Sphingobacteriia	976|Bacteroidetes	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
k59_71956_1	1056820.KB900637_gene216	5.72e-12	70.9	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,2PMK9@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	PQQ-like domain	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_85766_2	1123054.KB907762_gene3417	1.42e-20	87.4	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1WYTC@135613|Chromatiales	135613|Chromatiales	L	ATP binding N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_173533_1	693444.D782_3117	5.34e-16	77.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,282QJ@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	U	TolQ protein	tolQ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_173533_2	1236541.BALL01000038_gene3720	1.98e-34	123.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,2QBY4@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM thioesterase superfamily protein	ybgC	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_0747,iSDY_1059.SDY_0684	4HBT
k59_71960_1	1215092.PA6_003_00720	2.04e-38	139.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1YCTI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	C-terminal region of band_7	qmcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k59_4434_1	1033802.SSPSH_003182	1.91e-14	71.6	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	rod shape-determining protein MreB	mreB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_4434_2	870187.Thini_3133	4.21e-34	119.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales	72273|Thiotrichales	H	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_4434_3	1166948.JPZL01000001_gene2473	2.03e-53	182.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XHA4@135619|Oceanospirillales	135619|Oceanospirillales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_99390_1	502025.Hoch_0168	2.85e-13	82.4	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
k59_180293_1	195105.CN97_08455	3.92e-45	158.0	COG0451@1|root,COG0451@2|Bacteria,1RKFJ@1224|Proteobacteria,2UAT9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_106134_2	387093.SUN_0830	6.61e-93	281.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42RRD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	L,D-transpeptidase catalytic domain	yafK	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_112386_1	395493.BegalDRAFT_2299	1.62e-80	251.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_166767_1	330214.NIDE4248	3.16e-43	153.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_106138_1	1165841.SULAR_00050	1.33e-78	233.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2YPE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	Hit family	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_160250_1	1232683.ADIMK_2773	5.83e-27	110.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,463YJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_160250_2	765913.ThidrDRAFT_2347	9.58e-65	203.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1WX3P@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
k59_4445_1	1208321.D104_10860	4.61e-99	296.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_139743_1	1347393.HG726025_gene2697	5.83e-26	109.0	COG5659@1|root,COG5659@2|Bacteria,4NQCF@976|Bacteroidetes,2FXFH@200643|Bacteroidia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_133250_1	215803.DB30_8592	6.2e-51	184.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,43BZC@68525|delta/epsilon subdivisions,2X7A3@28221|Deltaproteobacteria,2YWPR@29|Myxococcales	28221|Deltaproteobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt
k59_65225_1	56107.Cylst_6101	7.8e-74	249.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_119699_1	1382359.JIAL01000001_gene678	4.03e-169	483.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_194107_1	1122201.AUAZ01000002_gene1134	8.41e-112	335.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,469GP@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_31458_1	765911.Thivi_2592	1.56e-56	189.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1WW2C@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_31458_2	768066.HELO_4445	1.2e-23	96.7	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XHVC@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_166774_1	937774.TEQUI_0231	1.8e-23	103.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,3T1VS@506|Alcaligenaceae	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_187152_1	765913.ThidrDRAFT_2339	8.43e-54	181.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_92484_2	436114.SYO3AOP1_1757	5.55e-124	368.0	COG0677@1|root,COG0677@2|Bacteria,2G4GH@200783|Aquificae	200783|Aquificae	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_71979_1	319225.Plut_1120	5.59e-06	50.8	COG2911@1|root,COG2911@2|Bacteria,1FDFV@1090|Chlorobi	1090|Chlorobi	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
k59_71979_2	1198232.CYCME_1400	1.31e-17	75.9	2E371@1|root,32Y6T@2|Bacteria,1N8D8@1224|Proteobacteria,1SCAF@1236|Gammaproteobacteria,463E9@72273|Thiotrichales	72273|Thiotrichales	S	YnbE-like lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
k59_31460_1	314278.NB231_12074	2.37e-103	324.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales	135613|Chromatiales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_4450_1	2340.JV46_02640	8.23e-77	254.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1JB0I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_147108_1	203122.Sde_3753	1.45e-35	135.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,46535@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0581 ABC-type phosphate transport system, permease component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_147108_2	1167006.UWK_00889	4.07e-16	77.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MHPU@213118|Desulfobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_214421_1	938709.AUSH02000069_gene1533	7.87e-13	72.0	COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes	976|Bacteroidetes	S	PFAM YhhN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
k59_58890_1	2340.JV46_21990	2.74e-155	445.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1J4HP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Phosphoenolpyruvate phosphomutase	aceA	GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b4015,iAF1260.b4015,iB21_1397.B21_03847,iBWG_1329.BWG_3671,iE2348C_1286.E2348C_4318,iEC042_1314.EC042_4377,iEC55989_1330.EC55989_4500,iECABU_c1320.ECABU_c45310,iECBD_1354.ECBD_4022,iECB_1328.ECB_03887,iECDH10B_1368.ECDH10B_4204,iECDH1ME8569_1439.ECDH1ME8569_3871,iECD_1391.ECD_03887,iECED1_1282.ECED1_4722,iECIAI1_1343.ECIAI1_4235,iECIAI39_1322.ECIAI39_4401,iECNA114_1301.ECNA114_4164,iECO103_1326.ECO103_4759,iECO111_1330.ECO111_4827,iECO26_1355.ECO26_5119,iECP_1309.ECP_4225,iECSE_1348.ECSE_4300,iECSF_1327.ECSF_3865,iECUMN_1333.ECUMN_4541,iECW_1372.ECW_m4374,iEKO11_1354.EKO11_4310,iETEC_1333.ETEC_4270,iEcDH1_1363.EcDH1_3982,iEcE24377_1341.EcE24377A_4557,iEcHS_1320.EcHS_A4249,iEcSMS35_1347.EcSMS35_4469,iEcolC_1368.EcolC_4015,iJN746.PP_4116,iJO1366.b4015,iJR904.b4015,iLF82_1304.LF82_0012,iNRG857_1313.NRG857_20015,iSDY_1059.SDY_4328,iUMNK88_1353.UMNK88_4859,iWFL_1372.ECW_m4374,iY75_1357.Y75_RS20880	ICL
k59_167107_1	297246.lpp0391	4.54e-103	318.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1JDM7@118969|Legionellales	118969|Legionellales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_52043_1	317025.Tcr_0488	9.13e-77	238.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,460S1@72273|Thiotrichales	72273|Thiotrichales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_126674_1	1123326.JFBL01000021_gene2589	2.32e-16	87.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_194457_1	911045.PSE_0148	2.03e-22	97.1	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2TQYA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_194457_2	72019.SARC_07995T0	7.29e-17	82.8	COG0617@1|root,KOG2159@2759|Eukaryota,38BGG@33154|Opisthokonta	33154|Opisthokonta	J	CTP:tRNA cytidylyltransferase activity	TRNT1	GO:0000049,GO:0000166,GO:0000959,GO:0000963,GO:0000965,GO:0001680,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0004810,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009022,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0031123,GO:0031974,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0034062,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042780,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0052929,GO:0070013,GO:0070566,GO:0071704,GO:0090304,GO:0090646,GO:0097159,GO:0097367,GO:0097747,GO:0140053,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1990180,GO:1990817	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd
k59_72320_1	1249627.D779_0228	4.31e-58	199.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_112672_1	1049564.TevJSym_ab01230	1.66e-35	128.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_79086_1	1565314.OA34_10285	3.93e-154	464.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_86119_1	886377.Murru_1521	3.25e-64	199.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,1I4NU@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB
k59_201109_1	335543.Sfum_3298	3.51e-06	47.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2MQNH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k59_1134_1	2340.JV46_10190	7.4e-118	350.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1J4E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0348 Polyferredoxin	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_156986_1	2340.JV46_27120	1.62e-125	375.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1J4HD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_89388_1	1049564.TevJSym_ak00550	1.77e-20	84.3	COG1918@1|root,COG1918@2|Bacteria,1NBG2@1224|Proteobacteria,1SE39@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Pfam FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_34954_1	1043205.AFYF01000028_gene267	3.55e-33	143.0	COG3087@1|root,COG3291@1|root,COG3087@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FHZF@85021|Intrasporangiaceae	201174|Actinobacteria	P	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Laminin_G_3,PKD
k59_102823_2	1168034.FH5T_07950	1.78e-09	58.5	COG4772@1|root,COG4772@2|Bacteria,4NF0U@976|Bacteroidetes,2FM7N@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_129860_1	1387312.BAUS01000007_gene2219	1.21e-30	113.0	COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,2VRYE@28216|Betaproteobacteria,2KMW8@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_143434_1	395493.BegalDRAFT_0733	2.06e-13	77.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
k59_184077_1	1282876.BAOK01000001_gene1871	2.98e-24	105.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
k59_211361_1	1254432.SCE1572_51425	6.29e-35	133.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2YU35@29|Myxococcales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_75613_1	471854.Dfer_2067	3.02e-43	159.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47JW1@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_7814_1	1165841.SULAR_05543	9.87e-106	322.0	COG0642@1|root,COG4564@1|root,COG0642@2|Bacteria,COG4564@2|Bacteria,1QZ2C@1224|Proteobacteria,42QBR@68525|delta/epsilon subdivisions,2YNQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_2,sCache_2
k59_96027_2	1165841.SULAR_08864	2.56e-51	165.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42RMF@68525|delta/epsilon subdivisions,2YP6U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_7817_1	1121468.AUBR01000078_gene859	3.97e-56	197.0	COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,25D02@186801|Clostridia,42FJ4@68295|Thermoanaerobacterales	186801|Clostridia	L	COGs COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Mu-transpos_C,rve
k59_82512_1	713586.KB900536_gene782	1.45e-87	268.0	COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,1RNYQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	cynR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11921,ko:K21757	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_211376_1	243090.RB13048	2.46e-08	61.2	COG1520@1|root,COG1520@2|Bacteria,2IWVJ@203682|Planctomycetes	203682|Planctomycetes	S	WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_82515_1	1165841.SULAR_03607	2.03e-30	116.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_82515_2	1165841.SULAR_03602	2.97e-50	174.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_150269_1	1278309.KB907101_gene353	7.19e-73	231.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,1XIET@135619|Oceanospirillales	135619|Oceanospirillales	G	C4-dicarboxylate ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_211386_1	187272.Mlg_0587	5.04e-25	104.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k59_211386_2	519989.ECTPHS_00475	5.65e-41	140.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales	135613|Chromatiales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_89401_2	1163617.SCD_n02607	1.95e-24	99.8	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2VUC4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_143448_1	2340.JV46_04180	3.36e-137	411.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1J4IX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_82526_1	1165841.SULAR_04367	2.36e-136	395.0	COG4487@1|root,COG4487@2|Bacteria,1MWNT@1224|Proteobacteria,42NKA@68525|delta/epsilon subdivisions,2YMC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
k59_1174_1	1165841.SULAR_01430	2.03e-58	185.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2YNHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_1174_2	387093.SUN_1437	1.99e-21	93.6	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,43B1H@68525|delta/epsilon subdivisions,2YT54@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_109585_1	1165841.SULAR_00570	2.58e-45	150.0	2EKI4@1|root,33E83@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68888_1	1165841.SULAR_00445	1.07e-79	246.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_68888_2	1165841.SULAR_00440	1.47e-06	48.5	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_34981_2	1047013.AQSP01000144_gene905	4.65e-06	47.8	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_41744_1	768671.ThimaDRAFT_3176	1.81e-47	182.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,1X2UA@135613|Chromatiales	135613|Chromatiales	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
k59_136663_1	1120953.AUBH01000008_gene330	1.05e-10	67.0	COG4191@1|root,COG4191@2|Bacteria,1RC0X@1224|Proteobacteria,1S3G6@1236|Gammaproteobacteria,46AM4@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_211402_1	387093.SUN_1379	1.56e-104	326.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,dCache_2
k59_163802_1	1168034.FH5T_04190	8e-113	327.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_109600_2	2340.JV46_04250	4.99e-57	186.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,1JC06@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_7839_1	1215092.PA6_020_00730	4.23e-19	86.3	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1YD91@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_7839_2	323261.Noc_0298	3.98e-81	253.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1WWQP@135613|Chromatiales	135613|Chromatiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_123131_1	1123247.AUIJ01000001_gene1731	1.08e-146	420.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1613_1	156889.Mmc1_3292	1.05e-92	290.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,2TW7V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_28833_1	1165841.SULAR_07585	9.05e-108	333.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_198261_1	46256.BBIK01000026_gene1849	1.03e-47	165.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,4AWTH@81850|Leuconostocaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	ysdB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_103255_1	686340.Metal_1041	4.74e-62	213.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XDY0@135618|Methylococcales	135618|Methylococcales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_69358_1	1406840.Q763_14750	2.47e-28	118.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia,2NS9E@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_137066_1	272844.PAB1498	5.21e-75	236.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,242WA@183968|Thermococci	183968|Thermococci	F	Aspartate carbamoyltransferase	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_49068_1	279714.FuraDRAFT_3786	3.04e-41	152.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,2KPG7@206351|Neisseriales	206351|Neisseriales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_35320_2	1165841.SULAR_09054	2.07e-65	213.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_55812_1	1260251.SPISAL_01020	9.66e-43	148.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_143730_1	886379.AEWI01000024_gene381	3.07e-28	109.0	COG3023@1|root,COG3103@1|root,COG3023@2|Bacteria,COG3103@2|Bacteria,4NE38@976|Bacteroidetes,2FVEF@200643|Bacteroidia,3XKNZ@558415|Marinilabiliaceae	976|Bacteroidetes	TV	Ami_2	-	-	3.5.1.28	ko:K11066	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2,SH3_3
k59_143730_2	886379.AEWI01000024_gene382	5.35e-35	124.0	2E5N5@1|root,330CZ@2|Bacteria,4PJ4K@976|Bacteroidetes,2G24X@200643|Bacteroidia,3XKK3@558415|Marinilabiliaceae	976|Bacteroidetes	S	Holin of 3TMs, for gene-transfer release	-	-	-	-	-	-	-	-	-	-	-	-	GTA_holin_3TM
k59_96513_1	1165841.SULAR_01788	5.74e-130	385.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_123502_1	519989.ECTPHS_01134	3.42e-95	301.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_35324_1	1165841.SULAR_06768	3.25e-180	526.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_28846_1	926566.Terro_3521	5.18e-43	160.0	COG0532@1|root,COG0532@2|Bacteria,3Y3UG@57723|Acidobacteria,2JHXH@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_8225_1	1123400.KB904746_gene1330	6.23e-139	411.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,45ZWA@72273|Thiotrichales	72273|Thiotrichales	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_116954_2	1204516.I6X7L1_9CAUD	5.39e-36	142.0	4QETB@10239|Viruses,4QZWI@35237|dsDNA viruses  no RNA stage,4QQJ2@28883|Caudovirales,4QK2X@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49082_1	1165841.SULAR_02943	3e-94	285.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_55820_1	1340493.JNIF01000003_gene3504	1.81e-58	192.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria	57723|Acidobacteria	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_55820_2	1163617.SCD_n00549	3.52e-14	70.1	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_8227_1	395493.BegalDRAFT_1705	1.85e-62	210.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,461IW@72273|Thiotrichales	72273|Thiotrichales	N	Gliding motility protein GldG	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_62667_1	575540.Isop_0993	4.63e-55	194.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	575540.Isop_0993|-	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
k59_42156_1	1144312.PMI09_05605	1.54e-77	239.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
k59_171023_1	1165841.SULAR_10364	7.52e-100	322.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1640_1	1122978.AUFP01000042_gene735	1.29e-07	49.3	2B9ZZ@1|root,323DM@2|Bacteria,4NTEB@976|Bacteroidetes,2FU8G@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1640_2	196164.23493383	3.43e-14	75.1	29WRJ@1|root,30ICM@2|Bacteria,2H09C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_116962_1	285535.JOEY01000126_gene834	7.34e-24	99.4	COG0686@1|root,COG0686@2|Bacteria,2GKMN@201174|Actinobacteria	201174|Actinobacteria	E	alanine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_9107_1	859657.RPSI07_mp1443	5.08e-86	263.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VHSE@28216|Betaproteobacteria,1K3GC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K12957,ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_70011_1	1165841.SULAR_03517	8.75e-56	178.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,433JY@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_70011_2	1165841.SULAR_03512	5.84e-91	274.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42PQE@68525|delta/epsilon subdivisions,2YNTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_144567_1	983917.RGE_19320	3.28e-33	129.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VP3I@28216|Betaproteobacteria,1KMPD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_2440_1	500637.PROVRUST_04769	8.06e-35	136.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1NFKU@1224|Proteobacteria,1RP2D@1236|Gammaproteobacteria,3Z7MB@586|Providencia	1236|Gammaproteobacteria	S	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_56506_1	980584.AFPB01000174_gene1637	7.77e-24	99.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1HXVZ@117743|Flavobacteriia,4068C@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_56506_2	1168034.FH5T_05865	2.39e-38	133.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,2FMJH@200643|Bacteroidia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_212435_1	1165841.SULAR_00040	4.63e-20	81.3	2BSSB@1|root,32MVI@2|Bacteria,1Q3ES@1224|Proteobacteria,42X7B@68525|delta/epsilon subdivisions,2YQUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212435_2	1165841.SULAR_00045	2.04e-73	236.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_22686_1	42345.XP_008779879.1	4.71e-47	171.0	COG2801@1|root,KOG0017@2759|Eukaryota,37W11@33090|Viridiplantae,3GN4U@35493|Streptophyta	35493|Streptophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs
k59_131062_1	2340.JV46_08130	1e-93	288.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1J5DJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_199108_1	1356854.N007_00735	1.15e-05	46.2	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,279IB@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_199108_2	1382359.JIAL01000001_gene2708	3.22e-35	135.0	COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria,2JII2@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_15944_1	7897.ENSLACP00000001461	1.67e-16	85.5	COG1524@1|root,KOG2645@2759|Eukaryota,38EE7@33154|Opisthokonta,3BC7K@33208|Metazoa,3CW1U@33213|Bilateria,48024@7711|Chordata,490AZ@7742|Vertebrata	33208|Metazoa	S	phosphodiesterase I activity	ENPP3	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002276,GO:0002366,GO:0002376,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002699,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004528,GO:0004551,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006955,GO:0008081,GO:0008150,GO:0008152,GO:0008270,GO:0008285,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009143,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0031347,GO:0031348,GO:0032101,GO:0032102,GO:0033003,GO:0033004,GO:0033006,GO:0033007,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036230,GO:0042127,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045321,GO:0045575,GO:0045595,GO:0046034,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047429,GO:0048471,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050789,GO:0050793,GO:0050794,GO:0050865,GO:0050866,GO:0050896,GO:0051147,GO:0051150,GO:0055086,GO:0065007,GO:0070663,GO:0070664,GO:0070666,GO:0070667,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0080134,GO:0090304,GO:0090305,GO:0098552,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901575,GO:1901576	3.1.4.1,3.6.1.9	ko:K01513	ko00230,ko00240,ko00500,ko00740,ko00760,ko00770,ko01100,map00230,map00240,map00500,map00740,map00760,map00770,map01100	-	R00056,R00087,R00103,R00160,R00287,R00515,R00662,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko00537,ko01000,ko04090	-	-	-	Endonuclease_NS,Phosphodiest,Somatomedin_B
k59_42886_1	1328313.DS2_14354	8.71e-59	192.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,464XR@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_164888_1	1122201.AUAZ01000050_gene180	6.96e-08	58.9	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,1T5RZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_185252_1	42256.RradSPS_2501	5.4e-72	231.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria,4CQUX@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_199118_1	1165841.SULAR_02318	8.92e-49	157.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42VVX@68525|delta/epsilon subdivisions,2YQGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_199118_2	485916.Dtox_2727	1.7e-18	82.8	COG0622@1|root,COG0622@2|Bacteria,1W44P@1239|Firmicutes,257A9@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42899_1	163908.KB235896_gene2428	2.94e-38	146.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,HisKA_3,PAS_9,Pkinase,Response_reg,SpoIIE
k59_131074_1	1042375.AFPL01000008_gene3154	4e-27	103.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,467E2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_131074_2	1515746.HR45_16790	5.03e-53	176.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,2QA83@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_212453_1	1278073.MYSTI_00537	1.44e-13	78.6	COG0515@1|root,COG0515@2|Bacteria,1Q38C@1224|Proteobacteria,433YY@68525|delta/epsilon subdivisions,2X44H@28221|Deltaproteobacteria,2YY8C@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
k59_29530_1	1165841.SULAR_02918	7.32e-99	309.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_22709_1	761193.Runsl_0933	4.92e-34	130.0	COG0641@1|root,COG0641@2|Bacteria,4NJNZ@976|Bacteroidetes,47Q0H@768503|Cytophagia	976|Bacteroidetes	C	radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	SPASM
k59_9130_1	1165841.SULAR_02698	2.22e-93	293.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2YRC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_104077_1	1089550.ATTH01000001_gene2237	3.72e-29	112.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_63428_1	391593.RCCS2_08329	5.63e-34	123.0	2DB77@1|root,2Z7K3@2|Bacteria,1NHMC@1224|Proteobacteria,2U06K@28211|Alphaproteobacteria,2P2NQ@2433|Roseobacter	28211|Alphaproteobacteria	C	Photosynthetic reaction centre protein	pufL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464	-	ko:K08928	ko02020,map02020	M00597	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Photo_RC
k59_36313_1	1120965.AUBV01000012_gene1410	2.42e-49	176.0	COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,47Y41@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_9307_2	291112.PAU_00582	3.33e-75	238.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422	Thymidylat_synt
k59_178594_1	387093.SUN_2194	1.45e-14	79.3	COG4773@1|root,COG4773@2|Bacteria,1PP2I@1224|Proteobacteria,42WFP@68525|delta/epsilon subdivisions,2YQM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_29723_1	1123355.JHYO01000031_gene1606	6.32e-185	521.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
k59_104271_1	1280952.HJA_02685	1.12e-09	56.2	COG2388@1|root,COG2388@2|Bacteria,1NKJW@1224|Proteobacteria,2UBEQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG,GFA
k59_178597_1	1125863.JAFN01000001_gene2568	1.19e-14	79.7	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_144765_1	234267.Acid_6986	4.03e-08	55.1	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
k59_144765_2	177437.HRM2_03790	6.9e-18	82.8	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_9313_1	237368.SCABRO_01197	1.66e-18	87.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_63608_2	2340.JV46_09930	1.86e-133	386.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1J4PY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	iYL1228.KPN_03597,ic_1306.c3945	polyprenyl_synt
k59_158506_1	1168034.FH5T_06720	8.51e-92	288.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,2FMI1@200643|Bacteroidia	976|Bacteroidetes	E	peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009987,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033218,GO:0034641,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
k59_205963_1	521003.COLINT_03235	4.73e-26	107.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CUX7@84998|Coriobacteriia	84998|Coriobacteriia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_205963_2	1313421.JHBV01000003_gene657	5.13e-08	55.5	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_144780_1	1173264.KI913949_gene122	1.47e-28	111.0	COG3415@1|root,COG3415@2|Bacteria,1G802@1117|Cyanobacteria	1117|Cyanobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32
k59_29752_1	1165841.SULAR_00695	2.63e-79	255.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2YMYH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_22860_1	313603.FB2170_11616	8.07e-96	300.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1HZT1@117743|Flavobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
k59_56714_1	1353537.TP2_13595	5.41e-23	97.4	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS5C@28211|Alphaproteobacteria,2XMGJ@285107|Thioclava	28211|Alphaproteobacteria	Q	COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_151690_1	765910.MARPU_10595	1.68e-114	366.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales	135613|Chromatiales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_90830_1	1165841.SULAR_06223	4.93e-111	340.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_56721_1	1165841.SULAR_04537	3.98e-113	329.0	COG0845@1|root,COG0845@2|Bacteria,1QE6S@1224|Proteobacteria,42QGG@68525|delta/epsilon subdivisions,2YNSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cmeE	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_144798_1	344747.PM8797T_27297	5.45e-12	68.6	COG4102@1|root,COG4102@2|Bacteria,2J2FA@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
k59_104295_1	1122194.AUHU01000002_gene2811	4.55e-14	68.9	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,468GH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_63639_1	1443665.JACA01000001_gene3025	5.08e-17	92.4	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1IKPF@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
k59_56724_1	1235792.C808_03991	0.000873	45.4	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,27KW7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_32513_1	1165841.SULAR_08714	2.31e-113	341.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria,1MUGA@1224|Proteobacteria,42NI0@68525|delta/epsilon subdivisions,2YNKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP citrate synthase	-	-	2.3.3.8	ko:K15230	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,Ligase_CoA
k59_134386_2	1249627.D779_2322	4.12e-17	80.1	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1WWCG@135613|Chromatiales	135613|Chromatiales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_46040_1	234267.Acid_7167	4.34e-109	338.0	COG5549@1|root,COG5549@2|Bacteria,3Y2IY@57723|Acidobacteria	57723|Acidobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_93670_1	1304883.KI912532_gene585	1.06e-13	69.7	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,2VNH9@28216|Betaproteobacteria,2KU7D@206389|Rhodocyclales	206389|Rhodocyclales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_38832_1	1165841.SULAR_00405	1.03e-122	363.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_52761_1	387093.SUN_1107	1.45e-92	298.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_5694_1	1165841.SULAR_00505	2.08e-36	135.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,42XAR@68525|delta/epsilon subdivisions,2YR2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_5694_2	1165841.SULAR_00510	3e-18	83.6	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2YMFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_195273_1	1128398.Curi_c23170	4.3e-55	188.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,267IP@186813|unclassified Clostridiales	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k59_93679_1	1049564.TevJSym_aa00660	2.14e-29	113.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1J587@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
k59_93679_2	1313301.AUGC01000008_gene434	3.62e-07	53.9	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes	976|Bacteroidetes	S	GumN protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_120852_1	1168034.FH5T_11360	5.48e-32	124.0	COG1502@1|root,COG1502@2|Bacteria,4NE2W@976|Bacteroidetes,2FMEA@200643|Bacteroidia	976|Bacteroidetes	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_52769_1	1131553.JIBI01000050_gene1003	5.63e-26	107.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG2	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_181453_1	1165841.SULAR_09489	1.88e-109	322.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,42MVH@68525|delta/epsilon subdivisions	1224|Proteobacteria	HJ	Sugar-transfer associated ATP-grasp	PA1766	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
k59_113380_1	4081.Solyc06g060030.1.1	9.34e-49	179.0	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae,3GG2K@35493|Streptophyta,44UC5@71274|asterids	35493|Streptophyta	L	Mitochondrial protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve,zf-CCHC
k59_127445_1	314278.NB231_16378	3.2e-66	221.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,1SKFJ@1236|Gammaproteobacteria,1X099@135613|Chromatiales	135613|Chromatiales	L	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_12018_1	2340.JV46_27320	1.36e-106	326.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1J4FF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_181458_1	1168034.FH5T_17895	1.17e-101	309.0	COG4231@1|root,COG4231@2|Bacteria,4NJM1@976|Bacteroidetes,2FMYS@200643|Bacteroidia	976|Bacteroidetes	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR_N,TPP_enzyme_C
k59_79895_1	748658.KB907316_gene490	2.17e-19	86.7	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1WXPT@135613|Chromatiales	135613|Chromatiales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_147905_1	1121405.dsmv_2651	2.85e-120	360.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_215224_1	929558.SMGD1_1739	4.32e-29	116.0	COG2984@1|root,COG2984@2|Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_93691_1	1493510.A0A0E3ICC1_9CAUD	1.36e-16	79.3	4QAQQ@10239|Viruses,4QPBX@28883|Caudovirales,4QIBM@10662|Myoviridae	10662|Myoviridae	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_93691_2	1283076.M1IP93_9CAUD	1.13e-103	321.0	4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses  no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae	10662|Myoviridae	S	Phage tail sheath protein	-	GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027	-	-	-	-	-	-	-	-	-	-	-
k59_5725_1	1283076.M1ICV0_9CAUD	5.18e-65	211.0	4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses  no RNA stage,4QPJE@28883|Caudovirales,4QI9Y@10662|Myoviridae	10662|Myoviridae	S	ATPase family associated with various cellular activities (AAA)	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_86777_1	572477.Alvin_1664	1.79e-08	54.7	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1WYNA@135613|Chromatiales	135613|Chromatiales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k59_86777_2	1207063.P24_16862	2.38e-15	77.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2TV2I@28211|Alphaproteobacteria,2JRYA@204441|Rhodospirillales	204441|Rhodospirillales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_80301_2	1165841.SULAR_07725	2.82e-55	181.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2YN3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0663	Chorismate_synt
k59_161764_1	1121396.KB892913_gene116	1.58e-58	197.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_161764_2	1250278.JQNQ01000001_gene3414	1.36e-50	178.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_134719_2	1165841.SULAR_05388	1.55e-47	152.0	2B0AZ@1|root,31SN0@2|Bacteria,1QQ84@1224|Proteobacteria,433DQ@68525|delta/epsilon subdivisions,2YSFU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_134719_3	1165841.SULAR_05383	2.46e-121	352.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2YM8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_94022_1	697282.Mettu_0698	5.3e-51	173.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XDY1@135618|Methylococcales	135618|Methylococcales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_87126_1	1288079.AUKN01000036_gene3934	2.56e-41	159.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,PP-binding,Thioesterase
k59_39281_1	1500893.JQNB01000001_gene169	9.21e-97	298.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1X453@135614|Xanthomonadales	135614|Xanthomonadales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_154854_1	1123355.JHYO01000016_gene1861	7.78e-96	284.0	COG1414@1|root,COG1414@2|Bacteria,1RA2W@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_121100_1	143224.JQMD01000002_gene1717	5.53e-08	54.7	COG2755@1|root,COG3669@1|root,COG2755@2|Bacteria,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HZNT@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Fucosidase_C
k59_121100_3	1168034.FH5T_05325	5.23e-10	58.5	28PU4@1|root,2ZCF6@2|Bacteria,4NTXA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73364_1	1123401.JHYQ01000003_gene2122	4.58e-126	377.0	COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1SN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_215678_1	1168034.FH5T_07335	5.66e-160	464.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,2FM97@200643|Bacteroidia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k59_66950_2	2340.JV46_05410	9.07e-101	308.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1J4ST@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0306 Phosphate sulphate permeases	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_6093_1	1321778.HMPREF1982_01994	1.37e-20	93.2	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2691N@186813|unclassified Clostridiales	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_202351_1	509635.N824_00410	1.24e-07	58.5	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IP8K@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_53170_1	1288826.MSNKSG1_00556	1.06e-149	432.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_66954_1	1033810.HLPCO_000763	0.00026	47.4	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,Peptidase_MA_2
k59_12467_1	666509.RCA23_c13130	1.54e-74	234.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2TTG7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	InterPro IPR001584 COGs COG2801	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_121115_1	391615.ABSJ01000047_gene2127	4.82e-62	206.0	COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,1J56H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_46499_1	329726.AM1_4493	6.66e-56	179.0	COG3350@1|root,COG3350@2|Bacteria,1G6RV@1117|Cyanobacteria	1117|Cyanobacteria	S	Yhs domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
k59_66967_1	314230.DSM3645_11631	2.49e-38	137.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k59_53181_1	1165841.SULAR_06793	1.39e-87	271.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_60205_1	269798.CHU_1632	8.1e-22	89.4	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,47Q95@768503|Cytophagia	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_60205_2	1168034.FH5T_04840	2.97e-35	133.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,2FNND@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_53183_1	1122176.KB903540_gene104	2.42e-27	115.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IUTX@117747|Sphingobacteriia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_107812_1	1211814.CAPG01000045_gene2449	4.85e-141	419.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_121128_1	1317122.ATO12_02605	8.09e-91	273.0	COG0823@1|root,COG0823@2|Bacteria,4NJN5@976|Bacteroidetes,1I0Y8@117743|Flavobacteriia,2YJ9X@290174|Aquimarina	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_94064_1	926549.KI421517_gene3402	4.75e-46	158.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47KNZ@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_94064_2	1004149.AFOE01000003_gene2193	1.5e-38	132.0	2DPRW@1|root,3334N@2|Bacteria,4NVB9@976|Bacteroidetes,1I5MZ@117743|Flavobacteriia	976|Bacteroidetes	J	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175200_1	598659.NAMH_1624	5.69e-07	49.3	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2YNWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_175200_2	1165841.SULAR_07950	1.19e-71	216.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2YPXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_175200_3	1165841.SULAR_07955	2.91e-119	341.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2YMUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_175200_4	1165841.SULAR_07960	6.56e-82	243.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2YT0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_175200_5	556267.HWAG_00160	1.64e-13	63.9	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2YQIN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_6095_1	1304880.JAGB01000001_gene169	8.22e-19	90.9	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_69720_1	1165841.SULAR_04252	1.39e-108	333.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2YNBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_198624_1	697281.Mahau_0741	1.31e-24	107.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,42EXS@68295|Thermoanaerobacterales	186801|Clostridia	E	M3B, thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k59_130610_1	1417296.U879_00310	4.08e-52	183.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	metal-binding protein	nqrF	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_35691_1	1168034.FH5T_05450	7.31e-63	198.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,2FSVU@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG14471 non supervised orthologous group	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_177994_1	1122179.KB890436_gene1334	2.38e-13	75.5	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
k59_137365_1	1159870.KB907784_gene247	6.23e-07	56.2	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2VIY0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_15513_1	313596.RB2501_03565	2.92e-98	291.0	COG1999@1|root,COG1999@2|Bacteria,4NGHC@976|Bacteroidetes,1HXW6@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	ypmQ	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_123864_1	2340.JV46_13970	4.39e-97	297.0	COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,1RQ44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_110374_1	870187.Thini_2792	6.87e-64	209.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,4600H@72273|Thiotrichales	72273|Thiotrichales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_110374_2	765912.Thimo_3278	9.62e-07	48.9	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1WVXJ@135613|Chromatiales	135613|Chromatiales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_205239_1	998674.ATTE01000001_gene808	8.83e-41	151.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,461JH@72273|Thiotrichales	72273|Thiotrichales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
k59_62998_1	1387197.AWGA01000039_gene1671	6.61e-30	117.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040	CPSase_sm_chain,GATase
k59_62998_2	582402.Hbal_1109	1.01e-10	61.2	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,43X25@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_157937_1	1279009.ADICEAN_02584	8.06e-110	333.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k59_164537_1	1049564.TevJSym_aa01830	4.1e-70	229.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1SNU0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_15517_1	87626.PTD2_01541	3.09e-05	46.2	COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,2Q01Z@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_29161_1	572477.Alvin_0777	1.35e-55	180.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_29162_1	1168034.FH5T_10870	4.98e-110	340.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,2FPAU@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_35705_1	1122599.AUGR01000001_gene119	1.85e-13	70.1	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1XKW6@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
k59_63435_1	1379698.RBG1_1C00001G0230	1.06e-37	142.0	COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria	2|Bacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_15959_1	751994.AGIG01000035_gene357	1.17e-75	244.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7VQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	soxB	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_70018_1	981085.XP_010109403.1	3.21e-36	122.0	2D40V@1|root,2STG3@2759|Eukaryota,381GS@33090|Viridiplantae,3GMA3@35493|Streptophyta,4JUQW@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70018_2	218851.Aquca_064_00050.1	1.4e-19	81.3	2D6E7@1|root,2T1Q5@2759|Eukaryota,382XC@33090|Viridiplantae,3GRGP@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70018_4	3649.evm.model.supercontig_23.86	4.49e-15	69.7	2EP17@1|root,2SSB9@2759|Eukaryota,380HF@33090|Viridiplantae,3GQ31@35493|Streptophyta,3I1B7@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70018_5	59689.Al_scaffold_0009_194	4.49e-05	43.5	2EXPB@1|root,2SZAU@2759|Eukaryota,3824W@33090|Viridiplantae,3GRW6@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212474_2	1123399.AQVE01000002_gene2372	3.57e-57	184.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales	72273|Thiotrichales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_104092_1	394503.Ccel_0858	3.02e-41	156.0	COG3321@1|root,COG3321@2|Bacteria,1VU8Z@1239|Firmicutes,24YJI@186801|Clostridia,36UKQ@31979|Clostridiaceae	186801|Clostridia	Q	Beta-ketoacyl synthase	-	-	-	ko:K13612	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_137878_1	1168034.FH5T_02825	1.57e-55	181.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes,2G0E5@200643|Bacteroidia	976|Bacteroidetes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_9148_1	1185876.BN8_01275	3.57e-108	332.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_164930_1	765912.Thimo_1827	2.1e-15	75.1	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1WW67@135613|Chromatiales	135613|Chromatiales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_164930_2	1429851.X548_13520	2.76e-34	125.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1X3NH@135614|Xanthomonadales	135614|Xanthomonadales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_97402_1	225117.XP_009343091.1	6.17e-23	94.4	COG2801@1|root,KOG0017@2759|Eukaryota,37TAQ@33090|Viridiplantae,3GDDG@35493|Streptophyta,4JUJN@91835|fabids	35493|Streptophyta	L	cytochrome c biogenesis	ccmFc	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	CcmF_C
k59_151503_1	710686.Mycsm_01635	2.82e-52	180.0	COG0346@1|root,COG0346@2|Bacteria,2IP2W@201174|Actinobacteria,23B6D@1762|Mycobacteriaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4,Polyketide_cyc2
k59_70035_1	357808.RoseRS_0707	0.000775	43.5	COG2345@1|root,COG2345@2|Bacteria,2G8V0@200795|Chloroflexi,375MI@32061|Chloroflexia	32061|Chloroflexia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_DeoR
k59_90625_2	1268303.RHODMAR_2950	9e-10	60.5	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4FXIN@85025|Nocardiaceae	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_151505_1	616991.JPOO01000003_gene2301	8.2e-66	205.0	COG0558@1|root,COG0558@2|Bacteria,4NHGH@976|Bacteroidetes,1HZ13@117743|Flavobacteriia	976|Bacteroidetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_185279_1	1121440.AUMA01000009_gene695	3.65e-64	209.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria,2M8UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_2487_1	557598.LHK_00855	3.37e-30	117.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,2KPK6@206351|Neisseriales	206351|Neisseriales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_171862_1	1355368.JART01000015_gene1942	1.85e-58	206.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2YN67@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD,Prok-TraM
k59_124380_1	1165841.SULAR_05313	8.03e-55	185.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_171866_2	314278.NB231_05741	4.37e-55	180.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1WW98@135613|Chromatiales	135613|Chromatiales	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_110845_1	1250232.JQNJ01000001_gene1557	2.26e-30	125.0	COG0457@1|root,COG4676@1|root,COG0457@2|Bacteria,COG4676@2|Bacteria,4NGJS@976|Bacteroidetes,1HWZQ@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_70050_1	1163409.UUA_09066	4.19e-13	75.5	COG3941@1|root,COG3941@2|Bacteria,1MZWI@1224|Proteobacteria,1RQ7Y@1236|Gammaproteobacteria,1X98I@135614|Xanthomonadales	135614|Xanthomonadales	S	Mu-like prophage protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_151517_1	998674.ATTE01000001_gene127	1.97e-55	192.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_131103_1	1121935.AQXX01000116_gene5172	4.36e-52	170.0	2EBC6@1|root,335CX@2|Bacteria,1NFQ1@1224|Proteobacteria,1SD3N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36148_1	1449976.KALB_3882	4.18e-47	173.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K04780,ko:K16432	ko01053,ko01055,map01053,map01055	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_25,NAD_binding_4,PP-binding,Thioesterase
k59_110847_2	981369.JQMJ01000004_gene2316	5.27e-25	105.0	COG2197@1|root,COG2197@2|Bacteria,2GIXB@201174|Actinobacteria,2NEEZ@228398|Streptacidiphilus	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_50064_1	1165841.SULAR_07630	6.11e-107	321.0	COG2888@1|root,COG2888@2|Bacteria,1MZH3@1224|Proteobacteria,42VBG@68525|delta/epsilon subdivisions,2YR8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2503_1	756272.Plabr_3627	1.34e-30	119.0	COG2133@1|root,COG2133@2|Bacteria,2IZH6@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
k59_131106_1	1121439.dsat_2904	7.28e-11	63.9	2AZ0G@1|root,31R6J@2|Bacteria,1NMSQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124399_1	1408473.JHXO01000008_gene2878	8.25e-37	127.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,2FTXK@200643|Bacteroidia	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_124399_2	1270196.JCKI01000008_gene1684	1.95e-31	119.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_199184_1	1123508.JH636440_gene2791	1.07e-12	73.6	COG2010@1|root,COG2010@2|Bacteria,2IZC1@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_83867_1	2340.JV46_25150	5.32e-65	201.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,1SQF5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_158364_1	1000565.METUNv1_01904	2.25e-15	76.3	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,2KW82@206389|Rhodocyclales	28216|Betaproteobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	epsR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_117789_1	1249627.D779_3032	4.13e-31	120.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S1NU@1236|Gammaproteobacteria,1X2A6@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_110856_1	1123399.AQVE01000006_gene3507	4.07e-76	243.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,45ZQG@72273|Thiotrichales	72273|Thiotrichales	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k59_199192_1	1122603.ATVI01000011_gene2059	1.29e-59	206.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1X374@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_83873_1	882086.SacxiDRAFT_1781	1.97e-34	139.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,Methyltransf_25,PP-binding
k59_63479_1	387093.SUN_1883	7.8e-56	175.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2YPYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_154497_1	1121920.AUAU01000028_gene1372	2.19e-08	64.7	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_25674_1	318167.Sfri_1812	4.43e-58	192.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
k59_25674_2	1280950.HJO_13721	1.09e-06	49.7	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,43Z2W@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_32622_1	2340.JV46_24120	6.1e-27	103.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1J56A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0625 Glutathione S-transferase	sspA	GO:0001000,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0008150,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0042594,GO:0043175,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N,GST_N_3
k59_32622_2	380358.XALC_1266	3e-50	169.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1X4Q1@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_174874_1	56780.SYN_00331	1.13e-96	285.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_174874_2	387093.SUN_2394	3.63e-22	95.5	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_8
k59_52828_1	382464.ABSI01000013_gene1616	3.11e-39	149.0	COG0612@1|root,COG0612@2|Bacteria,46UTT@74201|Verrucomicrobia,2ITM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_19191_1	234621.RER_35570	6.37e-18	85.1	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4FTX1@85025|Nocardiaceae	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_19191_2	511051.CSE_11860	4.17e-07	53.9	COG0769@1|root,COG0769@2|Bacteria	2|Bacteria	M	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	murE	-	6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_168149_2	1122165.AUHS01000017_gene1818	8.54e-68	213.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1JC5V@118969|Legionellales	118969|Legionellales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_147970_1	1165841.SULAR_03747	8.98e-108	325.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2YNB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_154503_1	2340.JV46_03780	1.76e-05	46.2	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1J4GN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_154503_2	765913.ThidrDRAFT_2042	1.82e-66	209.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1WXKW@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_154503_3	555778.Hneap_2183	2.76e-17	76.6	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1WYM1@135613|Chromatiales	135613|Chromatiales	U	TIGRFAM preprotein translocase, YajC subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_5777_1	697282.Mettu_4063	4.63e-29	118.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1XEBF@135618|Methylococcales	135618|Methylococcales	MU	TIGRFAM type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_86824_1	1049564.TevJSym_ao00260	3.56e-52	187.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1J4G3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iG2583_1286.G2583_0058	OstA,OstA_C
k59_182093_1	641526.ADIWIN_1573	1.63e-23	91.7	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1I21M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_182093_2	688270.Celal_0033	9.27e-71	218.0	COG3279@1|root,COG3279@2|Bacteria,4NFN4@976|Bacteroidetes,1HYAZ@117743|Flavobacteriia,1F7TF@104264|Cellulophaga	976|Bacteroidetes	K	COGs COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_113910_1	1123242.JH636434_gene3727	3.73e-68	233.0	COG1450@1|root,COG1450@2|Bacteria,2IX4B@203682|Planctomycetes	203682|Planctomycetes	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_100921_1	1120965.AUBV01000015_gene1058	4.38e-35	133.0	COG5337@1|root,COG5337@2|Bacteria,4P3EE@976|Bacteroidetes	976|Bacteroidetes	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
k59_107968_1	948565.AFFP02000005_gene462	1.19e-22	96.7	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1Y6YV@135625|Pasteurellales	135625|Pasteurellales	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_127951_2	118168.MC7420_2165	2.88e-62	209.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_39465_1	1122132.AQYH01000002_gene1283	3.6e-106	323.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,4BAGU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_67186_1	1122212.AULO01000008_gene1425	0.000478	49.3	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1XIND@135619|Oceanospirillales	135619|Oceanospirillales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k59_80514_2	1165841.SULAR_07730	1.7e-50	164.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2YP63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_148543_1	1265505.ATUG01000002_gene1713	1.18e-83	272.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,42P3Z@68525|delta/epsilon subdivisions,2WKRN@28221|Deltaproteobacteria,2MJ14@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer2_BFD,GCV_T,GCV_T_C,Pyr_redox_2
k59_94249_1	861299.J421_0905	4.2e-09	61.2	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_33197_1	1524467.IV04_18485	1.12e-78	247.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,40000@613|Serratia	1236|Gammaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUTI89_1310.UTI89_C0772,iZ_1308.Z0993	Aminotran_3
k59_168767_1	4081.Solyc11g056370.1.1	6.83e-44	144.0	COG0838@1|root,KOG4662@2759|Eukaryota,37UUF@33090|Viridiplantae,3GIT0@35493|Streptophyta	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad3	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K03880	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q4
k59_100925_2	7668.SPU_028768-tr	3.45e-69	238.0	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3DE2J@33213|Bilateria	33208|Metazoa	L	Pao retrotransposon peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1758,DUF1759,Peptidase_A17,RVT_1,rve
k59_60366_1	321332.CYB_0679	2.59e-53	178.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1GZ5I@1129|Synechococcus	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
k59_121344_1	1168034.FH5T_03175	8.62e-63	195.0	2ET9N@1|root,33KTN@2|Bacteria,4NZKP@976|Bacteroidetes,2FZMH@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148548_1	1123228.AUIH01000022_gene3107	4.81e-53	187.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XHF9@135619|Oceanospirillales	135619|Oceanospirillales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_80527_1	3218.PP1S346_18V6.1	7.25e-57	198.0	COG3914@1|root,KOG4626@2759|Eukaryota,37IV9@33090|Viridiplantae,3G9DX@35493|Streptophyta	35493|Streptophyta	GOT	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY	SPY	GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_16,TPR_7,TPR_8
k59_121351_1	716541.ECL_01383	8.45e-44	151.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,1RRDM@1236|Gammaproteobacteria,3X329@547|Enterobacter	1236|Gammaproteobacteria	S	Belongs to the UPF0149 family	yecA	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
k59_141417_1	1168034.FH5T_19610	7.17e-100	306.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,2G2RU@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
k59_67208_1	398580.Dshi_1709	2.66e-115	345.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2U3WC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
k59_121353_1	682795.AciX8_0676	1.12e-13	79.3	COG3209@1|root,COG3209@2|Bacteria,3Y7FC@57723|Acidobacteria,2JKK9@204432|Acidobacteriia	204432|Acidobacteriia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
k59_12703_1	1165841.SULAR_01593	2.42e-25	94.7	2AKC8@1|root,31B36@2|Bacteria,1Q6TQ@1224|Proteobacteria,433T1@68525|delta/epsilon subdivisions,2YSPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12703_2	1165841.SULAR_01588	9.65e-45	146.0	COG1254@1|root,COG1254@2|Bacteria,1Q88S@1224|Proteobacteria,42WDB@68525|delta/epsilon subdivisions,2YQCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
k59_12703_3	1165841.SULAR_01583	6.48e-30	109.0	2AYIJ@1|root,319EA@2|Bacteria,1Q2GZ@1224|Proteobacteria,42VPA@68525|delta/epsilon subdivisions,2YQB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80534_1	4155.Migut.D01328.1.p	1.66e-55	175.0	COG0096@1|root,KOG1754@2759|Eukaryota,37UMN@33090|Viridiplantae,3GIWP@35493|Streptophyta,44TEK@71274|asterids	35493|Streptophyta	J	Ribosomal protein S8	rps8	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14,Ribosomal_L16,Ribosomal_S8
k59_80534_2	3649.evm.model.supercontig_0.195	3.65e-52	169.0	COG0093@1|root,COG0197@1|root,KOG0901@2759|Eukaryota,KOG3422@2759|Eukaryota,383TF@33090|Viridiplantae,3GWN0@35493|Streptophyta,3I06C@3699|Brassicales	35493|Streptophyta	J	Ribosomal protein L16p/L10e	-	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14,Ribosomal_L16
k59_168782_1	203122.Sde_0732	4.91e-92	283.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,464ND@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0229 family	yeaH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
k59_107997_1	2340.JV46_15900	1.63e-100	311.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1J9M8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PBP_dimer,Transpeptidase
k59_175481_1	1168034.FH5T_04080	3.62e-05	45.4	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_113940_1	1165841.SULAR_00555	9.59e-30	107.0	2AK3E@1|root,31AT6@2|Bacteria,1Q635@1224|Proteobacteria,432B1@68525|delta/epsilon subdivisions,2YSJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_113940_2	387093.SUN_0826	5.04e-33	121.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2YQCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NlpC/P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SPOR
k59_80538_1	644801.Psest_3613	1.11e-82	272.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1Z1J8@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_6272_1	452637.Oter_3802	5.65e-69	233.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia,3K7E7@414999|Opitutae	414999|Opitutae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_175488_1	1541065.JRFE01000006_gene4681	0.000233	44.3	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3S2@1117|Cyanobacteria,3VM13@52604|Pleurocapsales	1117|Cyanobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	Condensation,PP-binding,Thioesterase
k59_202572_1	1128398.Curi_c18410	3.8e-69	219.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,26827@186813|unclassified Clostridiales	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_148560_1	1165841.SULAR_05433	4.09e-22	90.5	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_148560_2	1165841.SULAR_05438	1.29e-99	299.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_175489_1	1165841.SULAR_07865	3.72e-45	147.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,42SBM@68525|delta/epsilon subdivisions,2YPGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_175489_2	387093.SUN_2280	9.27e-31	110.0	COG3411@1|root,COG3411@2|Bacteria,1N0XK@1224|Proteobacteria,42SE0@68525|delta/epsilon subdivisions,2YPJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
k59_182139_1	745718.JADT01000015_gene2897	9.99e-37	133.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
k59_46746_2	71139.XP_010026055.1	8.75e-09	58.5	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta	35493|Streptophyta	E	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	G-patch,RVT_1,RVT_3,Retrotrans_gag,rve
k59_33223_1	1165841.SULAR_09074	1.34e-98	299.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_209381_1	2340.JV46_27480	0.000125	43.5	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1J530@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	FP	Belongs to the GppA Ppx family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_209381_2	2340.JV46_05590	3.76e-36	126.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1J6VX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	RnfH family Ubiquitin	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
k59_209381_3	2340.JV46_05600	9.44e-63	196.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1J6IB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG2867 Oligoketide cyclase lipid transport protein	ratA	GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_108020_1	1165841.SULAR_10694	1.98e-61	193.0	COG5501@1|root,COG5501@2|Bacteria	2|Bacteria	-	-	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ,TAT_signal
k59_108020_2	1165841.SULAR_10699	7.44e-14	67.4	COG1397@1|root,COG1397@2|Bacteria,1PUW9@1224|Proteobacteria,42Z7N@68525|delta/epsilon subdivisions,2YR1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_80558_2	643867.Ftrac_3598	5.39e-61	206.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
k59_19735_1	1210884.HG799463_gene9989	3.66e-10	61.2	COG1595@1|root,COG1595@2|Bacteria,2IZXS@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_182153_1	1165841.SULAR_01465	1.46e-150	436.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2YN1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_97786_1	379731.PST_1363	3.84e-34	131.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1Z1VP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_50328_1	1165841.SULAR_05673	1.63e-20	90.9	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_50328_2	1165841.SULAR_05678	1.36e-97	287.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_50328_3	1150621.SMUL_0069	1.44e-08	56.2	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_199410_1	1165841.SULAR_03078	2.03e-76	229.0	2BMN0@1|root,32G77@2|Bacteria,1Q0X8@1224|Proteobacteria,42SM0@68525|delta/epsilon subdivisions,2YPGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_199410_2	1167006.UWK_02860	8.3e-42	144.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,42Q8Q@68525|delta/epsilon subdivisions,2WMKQ@28221|Deltaproteobacteria,2MIYE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_165584_1	1506583.JQJY01000004_gene3070	6.15e-41	147.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia,2NSUB@237|Flavobacterium	976|Bacteroidetes	E	Cystathionine beta-lyase	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_145445_1	1165841.SULAR_09154	2.4e-78	241.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2YMCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_3223_1	1165841.SULAR_00865	3.27e-46	158.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,42RPB@68525|delta/epsilon subdivisions,2YP5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_138449_1	572480.Arnit_0404	7.47e-114	338.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,42PB4@68525|delta/epsilon subdivisions,2YNJ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_23336_1	2340.JV46_20690	3.16e-87	268.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1J537@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	AI-2E family transporter	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_145446_1	545264.KB898749_gene191	2.52e-09	55.1	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1WYJN@135613|Chromatiales	135613|Chromatiales	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_145446_2	1121939.L861_10830	6.28e-31	115.0	COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,1SAXI@1236|Gammaproteobacteria,1XR0T@135619|Oceanospirillales	135619|Oceanospirillales	T	Universal stress protein UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_165585_1	411469.EUBHAL_00740	7.29e-11	66.2	COG3316@1|root,COG3316@2|Bacteria,1UK6Y@1239|Firmicutes,24RFW@186801|Clostridia	186801|Clostridia	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C
k59_178977_1	396588.Tgr7_1800	1.05e-53	187.0	COG1518@1|root,COG3344@1|root,COG1518@2|Bacteria,COG3344@2|Bacteria,1MUKK@1224|Proteobacteria,1RNYK@1236|Gammaproteobacteria,1WWHK@135613|Chromatiales	1236|Gammaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	-	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k59_36709_1	317619.ANKN01000024_gene1584	2.16e-36	133.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
k59_98149_1	143224.JQMD01000002_gene669	3.31e-39	147.0	COG1621@1|root,COG1621@2|Bacteria,4NG4M@976|Bacteroidetes,1HZSX@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_178978_1	998674.ATTE01000001_gene3543	1.17e-116	343.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,1RYCX@1236|Gammaproteobacteria,461K5@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
k59_9863_1	633697.EubceDRAFT1_1450	2.35e-36	135.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,25UXZ@186806|Eubacteriaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_9863_2	1089553.Tph_c00330	2.95e-62	201.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,42F5R@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_70776_1	1269813.ATUL01000004_gene2243	3.09e-06	47.8	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WWV1@135613|Chromatiales	135613|Chromatiales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_70776_2	1123257.AUFV01000012_gene2925	1.08e-34	130.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1X5H4@135614|Xanthomonadales	135614|Xanthomonadales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3235_1	1173026.Glo7428_4866	2.33e-34	131.0	COG1473@1|root,COG1473@2|Bacteria,1G01G@1117|Cyanobacteria	2|Bacteria	S	PFAM Peptidase family M20 M25 M40	yxeP_1	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_138462_1	746697.Aeqsu_2076	1.33e-22	100.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,Laminin_G_3,P_proprotein
k59_138462_2	370438.PTH_1843	7.25e-38	132.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,261UI@186807|Peptococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_23355_1	1123368.AUIS01000004_gene149	7.38e-32	125.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,2NBVV@225057|Acidithiobacillales	225057|Acidithiobacillales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_125096_1	313596.RB2501_07780	2.22e-44	155.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_125096_2	1348583.ATLH01000031_gene2109	1.85e-17	79.3	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1I1E3@117743|Flavobacteriia,1F7XI@104264|Cellulophaga	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_213167_1	1112209.AHVZ01000009_gene2697	1.85e-21	97.4	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,3NR79@468|Moraxellaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
k59_213167_2	1189612.A33Q_0369	2.98e-18	83.2	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,47ND4@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_30369_1	946077.W5A_01845	9.91e-40	138.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1I1EE@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
k59_30369_2	1086011.HJ01_01244	3.28e-11	63.2	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2NSB8@237|Flavobacterium	976|Bacteroidetes	S	Hemolysin	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_152198_1	351348.Maqu_4228	6.78e-125	360.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,4679W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_158952_1	2340.JV46_29080	4.7e-77	245.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1J4EF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1519 3-deoxy-D-manno-octulosonic-acid transferase	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
k59_64069_1	765911.Thivi_2664	8.97e-67	215.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria,1SHHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
k59_206465_1	1047013.AQSP01000123_gene1522	1.44e-25	110.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_16591_1	1165841.SULAR_00070	1.54e-106	318.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2YMG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_152202_1	1392490.JHZX01000001_gene2028	3.75e-68	231.0	COG4677@1|root,COG4677@2|Bacteria,4PNFN@976|Bacteroidetes,1I0J5@117743|Flavobacteriia	976|Bacteroidetes	G	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase,TSP_3
k59_77627_1	1165841.SULAR_06898	3.08e-73	239.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_77627_2	387093.SUN_2045	5.57e-41	142.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2YN7B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
k59_199790_1	545694.TREPR_3511	8.42e-55	194.0	COG3604@1|root,COG3604@2|Bacteria,2J5TK@203691|Spirochaetes	203691|Spirochaetes	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k59_158956_1	1168034.FH5T_05795	1.63e-84	278.0	COG3250@1|root,COG3250@2|Bacteria,4NKZX@976|Bacteroidetes,2FNTC@200643|Bacteroidia	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
k59_206469_1	1144342.PMI40_04849	7.8e-30	117.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2VHXH@28216|Betaproteobacteria,4723V@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
k59_165614_1	1056820.KB900661_gene3925	2.31e-07	51.6	COG2220@1|root,COG2220@2|Bacteria,1R4BX@1224|Proteobacteria,1RS4A@1236|Gammaproteobacteria,2PPGR@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
k59_165614_2	1237149.C900_01680	1.95e-17	82.8	COG2175@1|root,COG2175@2|Bacteria,4P1R5@976|Bacteroidetes,47WG6@768503|Cytophagia	976|Bacteroidetes	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
k59_145466_1	1165841.SULAR_02058	1.24e-107	320.0	COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,42U81@68525|delta/epsilon subdivisions,2YR2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_4
k59_178993_1	314287.GB2207_07537	4.37e-71	235.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1J4JG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	scpA	GO:0003674,GO:0003824,GO:0004494,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0019842,GO:0031419,GO:0036094,GO:0046906,GO:0048037,GO:0097159,GO:1901363	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_3653,iECO26_1355.ECO26_4004	B12-binding,MM_CoA_mutase
k59_206470_1	443152.MDG893_18974	1.3e-20	99.8	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_213182_1	313596.RB2501_03210	6.69e-110	329.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia	976|Bacteroidetes	F	nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_111467_1	1168034.FH5T_02935	1e-90	274.0	COG0657@1|root,COG0657@2|Bacteria,4NNWF@976|Bacteroidetes,2G18S@200643|Bacteroidia	976|Bacteroidetes	I	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
k59_30379_1	1121875.KB907550_gene638	7.56e-77	242.0	COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_178996_1	1117318.PRUB_09109	4.27e-41	150.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,2Q13Z@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_186018_1	1121943.KB900005_gene3999	1.78e-41	154.0	COG3666@1|root,COG3666@2|Bacteria,1Q0SK@1224|Proteobacteria,1SQNW@1236|Gammaproteobacteria,1XPP8@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_23383_1	555778.Hneap_1340	4.3e-27	106.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,1SCVK@1236|Gammaproteobacteria,1WZND@135613|Chromatiales	135613|Chromatiales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_111476_1	1165841.SULAR_06793	7.34e-100	302.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_152223_1	1070319.CAGGBEG34_190050	1.15e-73	247.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K25W@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Efflux pump membrane transporter	bpeB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_158975_1	292415.Tbd_1280	1.01e-70	226.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,1KSGA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_84599_1	313596.RB2501_06875	3.99e-97	289.0	COG3064@1|root,COG3064@2|Bacteria,4NESI@976|Bacteroidetes,1HXS4@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_145489_1	857087.Metme_3863	1.23e-80	263.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1XG25@135618|Methylococcales	135618|Methylococcales	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_213207_1	1175306.GWL_04340	3.43e-12	64.3	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,2VQER@28216|Betaproteobacteria,474MD@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gst3	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
k59_64095_2	314230.DSM3645_28137	1.12e-39	135.0	COG3436@1|root,COG3436@2|Bacteria,2J11P@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_3274_1	438753.AZC_1303	7.14e-108	332.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2015, Alkyl sulfatase and related hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_140639_1	395493.BegalDRAFT_0902	8.15e-150	431.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,461TD@72273|Thiotrichales	72273|Thiotrichales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_215049_1	2340.JV46_18530	5.5e-79	257.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1J4QN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009436,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iJN746.PP_0356,iWFL_1372.ECW_m3242	Malate_synthase
k59_25686_1	395493.BegalDRAFT_0393	3.52e-46	159.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,45ZNK@72273|Thiotrichales	72273|Thiotrichales	NU	PFAM Type II IV secretion system protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_134439_1	1537915.JU57_05185	5.35e-100	318.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_208842_1	65071.PYU1_T003453	4.51e-09	64.3	COG1506@1|root,KOG2281@2759|Eukaryota,1MGFA@121069|Pythiales	121069|Pythiales	O	Dipeptidyl peptidase. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
k59_113438_1	1279017.AQYJ01000021_gene2815	9e-45	156.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,1RN43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Choloylglycine hydrolase	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_86829_2	1165841.SULAR_01808	2.42e-96	284.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42TAK@68525|delta/epsilon subdivisions,2YPP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_140893_1	314278.NB231_03952	1.43e-06	56.2	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1WZ5E@135613|Chromatiales	135613|Chromatiales	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
k59_215295_1	57918.XP_004301673.1	4.81e-19	89.7	COG2801@1|root,KOG0017@2759|Eukaryota,37R6P@33090|Viridiplantae,3G8BW@35493|Streptophyta,4JN0G@91835|fabids	35493|Streptophyta	L	Uncharacterized protein K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,RVT_3,Retrotrans_gag,rve
k59_19206_1	1168034.FH5T_22140	3.51e-61	201.0	COG0860@1|root,COG1463@1|root,COG0860@2|Bacteria,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,2FPK9@200643|Bacteroidia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_66659_1	1232410.KI421418_gene2364	3.59e-68	220.0	28MC7@1|root,2ZBGF@2|Bacteria,1R7M9@1224|Proteobacteria	1224|Proteobacteria	S	DpnII restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DpnII
k59_79977_1	1249627.D779_3936	6.85e-65	202.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,1WX7S@135613|Chromatiales	135613|Chromatiales	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_107463_1	1123277.KB893243_gene184	2.05e-20	95.1	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,47JHQ@768503|Cytophagia	976|Bacteroidetes	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_12,TPR_7,TPR_8
k59_174892_1	1165841.SULAR_06603	0.000701	40.4	COG1017@1|root,COG1017@2|Bacteria,1QUQ4@1224|Proteobacteria,42R0F@68525|delta/epsilon subdivisions,2YP24@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the globin family	cgb	-	1.14.12.17	ko:K05916	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	Globin
k59_174892_2	1165841.SULAR_06598	3.04e-109	317.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,42RSQ@68525|delta/epsilon subdivisions,2YRW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k59_38948_1	504472.Slin_4666	2.37e-37	137.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,47N0C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_25713_1	1121405.dsmv_2856	4.02e-81	261.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_113443_1	1121875.KB907550_gene869	1.35e-33	123.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_113443_2	1121875.KB907550_gene868	6.19e-67	214.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia	976|Bacteroidetes	EJ	GlutRNAGln amidotransferase subunit D	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_161486_1	561229.Dd1591_1467	4.09e-25	112.0	COG1205@1|root,COG1205@2|Bacteria,1QTSR@1224|Proteobacteria,1T1FX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF1998,Helicase_C
k59_134456_1	1108045.GORHZ_247_00260	1.35e-65	229.0	COG3209@1|root,COG5412@1|root,COG3209@2|Bacteria,COG5412@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
k59_38960_1	472759.Nhal_2432	5.63e-69	216.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_161491_1	313596.RB2501_09180	1.03e-97	295.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_25721_1	1030157.AFMP01000008_gene3254	5.83e-15	75.1	COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,2TTJ4@28211|Alphaproteobacteria,2K20K@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_25721_2	469383.Cwoe_2289	1.29e-43	159.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4CS56@84995|Rubrobacteria	84995|Rubrobacteria	EI	ArgK protein	-	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_52864_1	1349767.GJA_3738	1.12e-25	110.0	2F1ZX@1|root,33UZ6@2|Bacteria,1NUV1@1224|Proteobacteria,2WC1W@28216|Betaproteobacteria,476VQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_208872_1	1286632.P278_33560	5.12e-20	87.8	29Q6S@1|root,30B5S@2|Bacteria,4NIX7@976|Bacteroidetes,1I0R1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_208872_2	1121094.KB894646_gene127	2.18e-21	85.9	COG0401@1|root,COG0401@2|Bacteria,4NUY1@976|Bacteroidetes,2FV78@200643|Bacteroidia,4AURH@815|Bacteroidaceae	976|Bacteroidetes	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
k59_107484_1	1385935.N836_06020	2.54e-30	118.0	COG1131@1|root,COG1131@2|Bacteria,1G11U@1117|Cyanobacteria,1H8ET@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_174902_1	545264.KB898751_gene2622	2.85e-112	338.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_73166_2	439375.Oant_1111	6.07e-57	185.0	COG3938@1|root,COG3938@2|Bacteria,1NVF9@1224|Proteobacteria,2TX8Z@28211|Alphaproteobacteria,1J1YQ@118882|Brucellaceae	28211|Alphaproteobacteria	G	4-hydroxyproline epimerase activity	-	GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006579,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0036361,GO:0042219,GO:0044237,GO:0044248,GO:0044270,GO:0047580,GO:0047661,GO:0071704,GO:1901564,GO:1901565,GO:1901575	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k59_154543_1	926559.JoomaDRAFT_1708	3.43e-82	258.0	COG2124@1|root,COG2124@2|Bacteria,4NG9Z@976|Bacteroidetes,1HY9E@117743|Flavobacteriia	976|Bacteroidetes	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
k59_93767_1	563040.Saut_1310	1.21e-141	423.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_195369_1	1502770.JQMG01000001_gene2416	3.85e-76	259.0	COG2304@1|root,COG2931@1|root,COG3898@1|root,COG5295@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3898@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,2KNPI@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VWA_2
k59_93768_1	443144.GM21_0990	2.27e-49	168.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,43T0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_38967_1	1007105.PT7_2483	2.44e-100	310.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,3T2I1@506|Alcaligenaceae	1224|Proteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_80004_1	742767.HMPREF9456_02192	1.19e-12	70.5	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,4NGZ0@976|Bacteroidetes,2FNI2@200643|Bacteroidia,2328A@171551|Porphyromonadaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	pleD	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k59_195375_1	472759.Nhal_2289	1.05e-104	312.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1WXSW@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_202112_1	592029.DDD_2394	6.89e-80	253.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1HZJI@117743|Flavobacteriia,3HJRR@363408|Nonlabens	976|Bacteroidetes	Q	FAD dependent oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_134476_1	7668.SPU_019679-tr	1.37e-40	145.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39N4Q@33154|Opisthokonta,3B9WN@33208|Metazoa,3D1S8@33213|Bilateria	33208|Metazoa	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_52883_2	103690.17130246	8.65e-22	103.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase
k59_208896_1	1165841.SULAR_10149	3.23e-112	340.0	COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,43BSV@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_188371_1	498211.CJA_0059	1.57e-13	72.8	2BWJV@1|root,32U7J@2|Bacteria,1N47S@1224|Proteobacteria,1S8XJ@1236|Gammaproteobacteria,1FI8Q@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86875_1	1165841.SULAR_02808	1.26e-178	513.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_140943_1	153948.NAL212_3117	7.62e-138	427.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase recycling family C-terminal	-	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N
k59_5838_1	1232437.KL661988_gene319	5.37e-45	166.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,438KJ@68525|delta/epsilon subdivisions,2X3V0@28221|Deltaproteobacteria,2MMUG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	hydroxyisourate hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_59898_1	1165841.SULAR_04417	6.19e-97	300.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_12108_1	886293.Sinac_6601	7.73e-07	54.7	COG1595@1|root,COG3170@1|root,COG1595@2|Bacteria,COG3170@2|Bacteria,2J20Z@203682|Planctomycetes	203682|Planctomycetes	KNU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_66700_2	1122179.KB890458_gene818	2.32e-24	107.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1J0HU@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_66700_3	34506.g2062	2.02e-29	117.0	COG1132@1|root,COG1720@1|root,KOG0055@2759|Eukaryota,KOG2942@2759|Eukaryota,38FMK@33154|Opisthokonta,3BAF0@33208|Metazoa,3D2P4@33213|Bilateria	33208|Metazoa	V	tRNA (adenine-N6-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_12110_1	1121875.KB907546_gene2830	1.98e-61	193.0	28P9K@1|root,2ZC31@2|Bacteria,4NPW6@976|Bacteroidetes,1I1KA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
k59_140953_1	1165841.SULAR_09264	4.45e-96	286.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2YN8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_208905_1	1165841.SULAR_02893	9.03e-101	300.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_127532_1	1239962.C943_02883	1.62e-56	192.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,47KIP@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
k59_148061_1	1123508.JH636455_gene6	1.47e-99	290.0	COG3865@1|root,COG3865@2|Bacteria,2IZP0@203682|Planctomycetes	203682|Planctomycetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
k59_46192_1	247634.GPB2148_3670	1.12e-53	173.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
k59_15303_1	313596.RB2501_07745	1.08e-73	232.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,1HY3H@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_76160_2	1168034.FH5T_00560	1.79e-23	99.8	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,2FNXZ@200643|Bacteroidia	976|Bacteroidetes	P	Enterochelin esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	AMPK1_CBM,CBM_48,Esterase
k59_157632_1	945713.IALB_1492	5.42e-41	149.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
k59_157632_2	1136417.AZWE01000009_gene2144	2.81e-12	67.8	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4DBHC@85008|Micromonosporales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
k59_62811_1	998088.B565_2310	1.35e-15	77.8	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1Y3HM@135624|Aeromonadales	135624|Aeromonadales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_62811_2	1249627.D779_2414	2.53e-38	130.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales	135613|Chromatiales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_110197_1	933262.AXAM01000019_gene1102	3.44e-104	312.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MIF1@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_157642_1	1049564.TevJSym_ap00670	1.1e-34	129.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1J4XT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
k59_49234_1	1165841.SULAR_03178	3.61e-61	194.0	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2YPTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3786 conserved	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_49234_2	1165841.SULAR_03173	2.28e-48	155.0	COG0810@1|root,COG0810@2|Bacteria,1PEYQ@1224|Proteobacteria,42WJI@68525|delta/epsilon subdivisions,2YQ9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
k59_110202_1	383372.Rcas_2386	6.79e-65	214.0	COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi	200795|Chloroflexi	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k59_204972_1	387093.SUN_0489	1.15e-180	509.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_204972_2	1165841.SULAR_09014	7.41e-50	162.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,42SFN@68525|delta/epsilon subdivisions,2YSYM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0227
k59_49240_1	1168034.FH5T_14195	2.12e-85	259.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,2FM91@200643|Bacteroidia	976|Bacteroidetes	F	Ser Thr phosphatase family protein	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
k59_35457_1	1165841.SULAR_01783	8.85e-112	327.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2YMPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_123679_2	1165841.SULAR_01320	4.09e-134	384.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42R15@68525|delta/epsilon subdivisions,2YNVA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_35459_1	983545.Glaag_2193	4.68e-50	169.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,464W3@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iJN746.PP_4253	Cytochrome_CBB3,FixP_N
k59_22036_1	1049564.TevJSym_bu00040	1.24e-99	323.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_49243_1	42565.FP66_00700	4.25e-46	152.0	COG3126@1|root,COG3126@2|Bacteria,1N8AF@1224|Proteobacteria,1SCM7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ybaY	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	YscW
k59_83201_1	926561.KB900621_gene2772	1.73e-20	94.7	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WBJB@53433|Halanaerobiales	186801|Clostridia	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_117102_1	477184.KYC_19434	6.04e-21	94.4	2AAD4@1|root,30ZP1@2|Bacteria,1NBWF@1224|Proteobacteria,2VXBU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123687_1	1249627.D779_2175	9.21e-121	364.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1WWMA@135613|Chromatiales	135613|Chromatiales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_177819_1	522306.CAP2UW1_4372	8.41e-70	226.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the NifD NifK NifE NifN family	nifN	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_150786_2	563040.Saut_0794	6.29e-18	82.0	2AJGA@1|root,31A2S@2|Bacteria,1Q4T9@1224|Proteobacteria,42ZUF@68525|delta/epsilon subdivisions,2YRSU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150786_3	1278307.KB906990_gene3107	8.07e-50	168.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,2QITP@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Patatin-like phospholipase	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_143888_1	388413.ALPR1_11965	2.73e-127	383.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47TP1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_171174_1	1002339.HMPREF9373_1483	1.05e-117	340.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,1SZQV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
k59_150790_1	3880.AES58578	1.66e-09	60.8	2CKHQ@1|root,2S5E8@2759|Eukaryota,37WKE@33090|Viridiplantae,3GKNN@35493|Streptophyta	35493|Streptophyta	S	BEST Arabidopsis thaliana protein match is Mitovirus RNA-dependent RNA polymerase (TAIR	-	-	-	-	-	-	-	-	-	-	-	-	Mitovir_RNA_pol
k59_211912_1	582515.KR51_00016460	1.37e-05	47.8	COG0358@1|root,COG0358@2|Bacteria,1G0TV@1117|Cyanobacteria	1117|Cyanobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
k59_211912_2	195250.CM001776_gene962	2.91e-41	139.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,HTH_3,HTH_31
k59_211912_4	56110.Oscil6304_2504	1.26e-41	142.0	COG2405@1|root,COG2405@2|Bacteria,1G5DX@1117|Cyanobacteria,1HBC1@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
k59_28981_1	1026882.MAMP_02515	8.52e-92	293.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_164360_1	1168034.FH5T_11570	1.59e-12	66.2	COG1509@1|root,COG1509@2|Bacteria,4NI73@976|Bacteroidetes,2G2FN@200643|Bacteroidia	976|Bacteroidetes	E	lysine 2,3-aminomutase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49258_1	745411.B3C1_03530	2.7e-52	179.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1J86Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_123702_1	1121405.dsmv_2602	2.79e-42	158.0	COG0642@1|root,COG0715@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0715@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MITZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_83223_1	1042377.AFPJ01000051_gene87	2.82e-43	154.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,46DHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_15332_1	304371.MCP_2981	6.41e-30	113.0	COG0456@1|root,arCOG00833@2157|Archaea,2XXV1@28890|Euryarchaeota	28890|Euryarchaeota	S	COG1246 N-acetylglutamate synthase and related acetyltransferases	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_15332_2	78898.MVEG_03572T0	0.00032	43.5	COG0169@1|root,KOG0692@2759|Eukaryota,38GV4@33154|Opisthokonta,3NTWM@4751|Fungi,1GS0B@112252|Fungi incertae sedis	4751|Fungi	E	The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis	ARO1	GO:0003674,GO:0003824,GO:0003855,GO:0003856,GO:0003866,GO:0004764,GO:0004765,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016765,GO:0016772,GO:0016773,GO:0016829,GO:0016835,GO:0016836,GO:0016838,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0055114,GO:0071704,GO:1901576	1.1.1.24,1.1.1.25,2.5.1.19,2.7.1.71,4.2.1.10,4.2.3.4	ko:K09484,ko:K13830	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01872,R02412,R02413,R03083,R03084,R03460	RC00002,RC00078,RC00154,RC00206,RC00350,RC00847,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,DHquinase_I,EPSP_synthase,SKI,Shikimate_DH,Shikimate_dh_N
k59_15335_1	1165841.SULAR_04482	2.61e-86	269.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_8355_1	768671.ThimaDRAFT_0802	6.48e-72	229.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,1X2B5@135613|Chromatiales	1236|Gammaproteobacteria	NU	PFAM Sulphatase-modifying factor	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,PEGA,Pkinase
k59_171188_1	1165841.SULAR_00100	2.54e-113	342.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_211923_1	1165841.SULAR_02978	1.57e-63	213.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria	1224|Proteobacteria	Q	Multi-copper	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_62830_1	1165841.SULAR_07670	1.28e-81	253.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,42ZSN@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_143906_1	261292.Nit79A3_1360	2.77e-80	271.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2WEJA@28216|Betaproteobacteria,374P7@32003|Nitrosomonadales	28216|Betaproteobacteria	EO	pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M1,Peptidase_M28
k59_198477_1	29730.Gorai.001G161700.1	1.12e-173	493.0	COG1622@1|root,KOG4767@2759|Eukaryota,37T4F@33090|Viridiplantae,3GGAX@35493|Streptophyta	35493|Streptophyta	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1	cox2	GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	ko:K02261	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX2,COX2_TM
k59_76234_1	1168034.FH5T_13490	1.28e-76	245.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
k59_150803_1	273121.WS1695	7.72e-26	97.8	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2YP8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_150803_2	1165841.SULAR_07905	1.79e-78	234.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2YP73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_150803_3	1165841.SULAR_07900	0.000141	42.7	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2YMCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_143913_1	767434.Fraau_0681	6.93e-81	245.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1X3DJ@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_69832_9	4081.Solyc01g007470.1.1	1.77e-75	227.0	COG0292@1|root,KOG4707@2759|Eukaryota,37VVT@33090|Viridiplantae,3GJCY@35493|Streptophyta	35493|Streptophyta	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rpl20	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0031967,GO:0031975,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_69832_10	29730.Gorai.010G129700.1	4.86e-54	170.0	KOG3162@1|root,KOG3162@2759|Eukaryota,37WM8@33090|Viridiplantae,3GJCQ@35493|Streptophyta	35493|Streptophyta	J	30S ribosomal protein S18, chloroplastic	rps18	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_69832_11	4081.Solyc01g067760.1.1	1.32e-24	93.2	2DZSX@1|root,2S79R@2759|Eukaryota,37WT4@33090|Viridiplantae,3GUGA@35493|Streptophyta,44UJ2@71274|asterids	35493|Streptophyta	C	Photosystem I reaction center subunit IX	-	-	-	ko:K02697	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PSI_PsaJ
k59_69832_12	13333.ERN02869	5.52e-54	171.0	2CHYC@1|root,2S3QA@2759|Eukaryota,37V66@33090|Viridiplantae,3GJP6@35493|Streptophyta	35493|Streptophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbE	-	-	ko:K02707,ko:K02713	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559,Cytochrom_B559a,PsbL
k59_69832_13	4565.EPlTAEP00000010029	1.48e-21	84.0	2E87T@1|root,2SEUE@2759|Eukaryota,37XI9@33090|Viridiplantae,3GMTY@35493|Streptophyta,3M1DX@4447|Liliopsida	35493|Streptophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02708	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559
k59_69832_14	4555.Si020883m	4.32e-20	80.5	2C8JW@1|root,2SBI8@2759|Eukaryota,37XIV@33090|Viridiplantae,3GMK0@35493|Streptophyta,3M8NW@4447|Liliopsida	35493|Streptophyta	S	Photosystem II protein J	psbJ	-	-	ko:K02711	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbJ
k59_35851_1	1165841.SULAR_08347	1.14e-140	418.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_63134_1	406817.XNC1_2299	1.13e-51	186.0	COG0500@1|root,COG1020@1|root,COG1020@2|Bacteria,COG2226@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Condensation,Methyltransf_25,PP-binding
k59_191848_1	391038.Bphy_2996	7.3e-06	54.7	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,1K2QG@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glyco_transf_41,MethyTransf_Reg,SEC-C,TPR_1,TPR_10,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
k59_205434_1	2340.JV46_05290	1.93e-154	450.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_35860_1	1120968.AUBX01000010_gene1156	1.14e-56	189.0	COG4461@1|root,COG4461@2|Bacteria,4NIBZ@976|Bacteroidetes,47QEU@768503|Cytophagia	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PliI
k59_164656_1	768671.ThimaDRAFT_1398	4.4e-16	79.7	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1WX9F@135613|Chromatiales	135613|Chromatiales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_164656_2	159087.Daro_1083	1.39e-16	78.2	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,2KW4R@206389|Rhodocyclales	28216|Betaproteobacteria	G	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k59_127297_2	1168034.FH5T_05705	3.22e-76	228.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,2FSPP@200643|Bacteroidia	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_167896_2	1123392.AQWL01000008_gene1146	3.8e-38	144.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
k59_100148_1	1249627.D779_1000	1.49e-87	266.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,1RNYE@1236|Gammaproteobacteria,1WW73@135613|Chromatiales	135613|Chromatiales	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_38668_1	1149133.ppKF707_6095	6.31e-70	222.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_25384_1	396595.TK90_0063	1.21e-48	163.0	2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,1RRV2@1236|Gammaproteobacteria,1WXVA@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_72961_1	1168034.FH5T_05695	1.3e-125	369.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,2FQNC@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_107213_1	237368.SCABRO_03556	4.63e-12	71.6	COG1357@1|root,COG1357@2|Bacteria,2J0M1@203682|Planctomycetes	203682|Planctomycetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
k59_38673_1	1235813.JCM10003_1047	1.38e-144	418.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia,4AKYN@815|Bacteroidaceae	976|Bacteroidetes	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_154261_1	1165841.SULAR_00865	1.12e-21	91.3	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,42RPB@68525|delta/epsilon subdivisions,2YP5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_154261_2	1165841.SULAR_00860	3.45e-88	264.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_25393_2	472759.Nhal_0142	2.31e-41	146.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1WW02@135613|Chromatiales	135613|Chromatiales	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
k59_18986_1	796606.BMMGA3_03470	9.17e-45	166.0	COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus	91061|Bacilli	N	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_208673_1	1123228.AUIH01000131_gene2866	2.94e-124	374.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1XS1N@135619|Oceanospirillales	135619|Oceanospirillales	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_120711_1	690850.Desaf_2573	2.85e-84	263.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,42Q8I@68525|delta/epsilon subdivisions,2X5IX@28221|Deltaproteobacteria,2MA7R@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_107221_1	1165841.SULAR_08884	4.91e-74	233.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2YMJJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	malic enzyme	mez	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_5572_1	756272.Plabr_0241	8.72e-58	192.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
k59_201901_1	1165841.SULAR_01310	4.97e-116	342.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YQ1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_134266_1	313596.RB2501_13749	7.11e-60	189.0	COG0668@1|root,COG0668@2|Bacteria,4NMMB@976|Bacteroidetes,1I2BV@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_66387_1	1168034.FH5T_03550	1.7e-63	207.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,2FUVZ@200643|Bacteroidia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
k59_66387_2	1168034.FH5T_03555	1.48e-42	144.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,2G2B1@200643|Bacteroidia	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_45945_1	1266925.JHVX01000005_gene1875	2.86e-06	54.3	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,371WD@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_188218_1	1122201.AUAZ01000008_gene467	3.88e-90	278.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_167932_1	1379270.AUXF01000003_gene3453	2.72e-103	312.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_161219_1	1168034.FH5T_05860	3.43e-41	147.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_215080_2	1504981.KO116_4679	3.99e-48	160.0	COG3415@1|root,COG3415@2|Bacteria,1QUXF@1224|Proteobacteria,1T24W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_215080_3	1249627.D779_2570	3.1e-138	403.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1WWFP@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k59_86639_1	314345.SPV1_02092	1.32e-67	225.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria	1224|Proteobacteria	S	fad dependent oxidoreductase	IV02_08645	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,FAD_binding_3,Pyr_redox_2
k59_134278_1	2340.JV46_16750	2.71e-104	311.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,1J5D1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_19015_2	1397528.Q671_03275	1.58e-32	125.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XHB6@135619|Oceanospirillales	135619|Oceanospirillales	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
k59_161225_1	1492737.FEM08_06180	9.78e-69	234.0	COG4206@1|root,COG4206@2|Bacteria,4NFRU@976|Bacteroidetes,1I0Y2@117743|Flavobacteriia,2NVQX@237|Flavobacterium	2|Bacteria	H	TIGRFAM SusC_RagA_signa TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_19020_1	768710.DesyoDRAFT_0050	7.99e-42	148.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,260K0@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_167938_1	2340.JV46_16280	9.34e-57	184.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1J6XG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yigP	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
k59_167938_2	2340.JV46_16290	2e-87	262.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1J4ZD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
k59_154280_1	349124.Hhal_1138	3.24e-26	102.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1WXCN@135613|Chromatiales	135613|Chromatiales	H	May be involved in the biosynthesis of molybdopterin	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_59582_1	1121405.dsmv_2573	1.64e-70	222.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,2MI0E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_195138_1	1131269.AQVV01000114_gene1804	1.67e-18	84.7	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_195138_2	1283300.ATXB01000001_gene925	9.99e-12	64.3	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1XE5C@135618|Methylococcales	135618|Methylococcales	O	ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_134497_1	4572.TRIUR3_00083-P1	2.84e-67	221.0	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,3KWRZ@4447|Liliopsida,3IFBD@38820|Poales	35493|Streptophyta	J	Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_5856_1	498761.HM1_1148	1.17e-53	177.0	COG0451@1|root,COG0451@2|Bacteria,1V8JZ@1239|Firmicutes,24UBU@186801|Clostridia	186801|Clostridia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_5856_2	395493.BegalDRAFT_1600	1.17e-12	67.4	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_195407_1	572480.Arnit_0089	1.11e-142	412.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_80045_1	1049564.TevJSym_aa00520	2.32e-28	103.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1J6G6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_80045_2	2340.JV46_26330	1.13e-47	153.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1J6MX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_134498_1	1079460.ATTQ01000010_gene1	1.18e-16	79.3	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,2VF65@28211|Alphaproteobacteria,4BJM0@82115|Rhizobiaceae	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_38996_2	2340.JV46_21920	1.42e-51	170.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,1T217@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	sensory box protein response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PilZ,Response_reg
k59_100453_1	572477.Alvin_2861	3.78e-33	130.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1WWAT@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_80048_1	983548.Krodi_2955	4.33e-71	228.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,37ECW@326319|Dokdonia	976|Bacteroidetes	F	CTP synthase N-terminus	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_134500_1	1165841.SULAR_09614	4.89e-145	420.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_140973_2	566466.NOR53_2285	1.02e-32	122.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1SJVR@1236|Gammaproteobacteria,1J7YK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_80049_1	504472.Slin_4900	7.06e-63	223.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_46214_1	471854.Dfer_0554	4.2e-104	315.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_46215_1	1165841.SULAR_09964	1.39e-98	288.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,42QP7@68525|delta/epsilon subdivisions,2YNWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
k59_134506_1	1168034.FH5T_04850	2.97e-72	219.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,2FPFU@200643|Bacteroidia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_134506_2	1168034.FH5T_04845	1.4e-52	167.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia	976|Bacteroidetes	FG	Histidine triad domain protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_32724_1	582744.Msip34_2269	3.41e-34	122.0	COG3133@1|root,COG3133@2|Bacteria,1RJWY@1224|Proteobacteria,2WE8P@28216|Betaproteobacteria,2KMTH@206350|Nitrosomonadales	206350|Nitrosomonadales	M	PFAM 17 kDa surface antigen	-	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
k59_76596_2	1250278.JQNQ01000001_gene3374	3.24e-30	120.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1HYNJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_151213_2	1185876.BN8_06062	1.95e-09	58.2	COG0239@1|root,COG0239@2|Bacteria,4PA5X@976|Bacteroidetes,47SST@768503|Cytophagia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_2239_1	1123399.AQVE01000006_gene3551	7.54e-11	68.6	COG3259@1|root,COG3259@2|Bacteria,1RFVW@1224|Proteobacteria,1T354@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
k59_8857_1	1254432.SCE1572_49540	4.6e-31	117.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,43CIK@68525|delta/epsilon subdivisions,2WQ8R@28221|Deltaproteobacteria,2Z1G2@29|Myxococcales	28221|Deltaproteobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k59_137591_1	1069080.KB913028_gene646	2.47e-19	90.5	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,4H30B@909932|Negativicutes	909932|Negativicutes	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_130879_1	1165841.SULAR_00235	2.66e-105	306.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2YPAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
k59_90432_1	1165841.SULAR_00080	1.08e-164	473.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_205554_1	722419.PH505_bl00280	6.99e-67	223.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,2Q1I5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	VP1725	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_22524_2	305900.GV64_20240	8.31e-58	182.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XK7A@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_22524_3	455436.DS989812_gene1341	3.6e-41	136.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,467YE@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_22524_4	1249627.D779_0567	3.56e-226	645.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales	135613|Chromatiales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_117499_1	314278.NB231_12671	2.24e-74	233.0	COG4715@1|root,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
k59_205556_1	388399.SSE37_20812	5.66e-25	102.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_110600_1	1033810.HLPCO_000287	3.95e-08	53.5	COG1986@1|root,COG1986@2|Bacteria,2NS1I@2323|unclassified Bacteria	2|Bacteria	F	Protein of unknown function DUF84	yjjX	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
k59_110600_2	1168034.FH5T_11820	1.55e-59	187.0	COG0454@1|root,COG0456@2|Bacteria,4NT3M@976|Bacteroidetes,2FYWS@200643|Bacteroidia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_8870_1	395493.BegalDRAFT_3277	2.85e-115	347.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CZB,EAL,GAF_2,GGDEF,NMT1,PAS,PAS_3,PAS_9,Phosphonate-bd,SBP_bac_3
k59_158160_1	313596.RB2501_15889	6.41e-27	107.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes,1HWJF@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_158160_2	1223410.KN050846_gene148	1.22e-23	94.7	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1I47G@117743|Flavobacteriia	976|Bacteroidetes	O	general stress protein	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
k59_56325_1	2340.JV46_23710	1.06e-31	113.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1J6H8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
k59_56325_2	96561.Dole_2838	1.74e-13	70.9	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,2MHUD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM oxidoreductase domain protein	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_42698_1	2340.JV46_27010	6.42e-45	157.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria,1J4S8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Malate:quinone oxidoreductase (Mqo)	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
k59_198939_1	1278307.KB906982_gene3940	1.36e-116	365.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QIXR@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9,Reg_prop
k59_151228_1	1123405.AUMM01000052_gene2639	2.83e-11	60.1	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,26P1C@186821|Sporolactobacillaceae	91061|Bacilli	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
k59_151228_2	401053.AciPR4_3676	4.98e-85	269.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_144355_1	497964.CfE428DRAFT_5914	7.78e-52	182.0	COG0367@1|root,COG0367@2|Bacteria,46UNK@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Asparagine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,GATase_7
k59_63250_1	665942.HMPREF1022_02940	5.02e-57	229.0	COG0553@1|root,COG0827@1|root,COG1040@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG4646@2|Bacteria,1PGZG@1224|Proteobacteria,42NYW@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	COG0827 Adenine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,Helicase_C,N6_Mtase,ResIII,SNF2_N
k59_117510_1	870187.Thini_0187	4.23e-69	213.0	COG2878@1|root,COG2878@2|Bacteria,1RE44@1224|Proteobacteria,1S5MU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_117510_2	870187.Thini_0186	1.47e-58	186.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,4604J@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
k59_49813_1	7668.SPU_025907-tr	1.04e-64	209.0	2BEH2@1|root,2S14S@2759|Eukaryota,39MAV@33154|Opisthokonta,3CNXX@33208|Metazoa,3E63V@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_90447_2	349521.HCH_00125	4.67e-62	200.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,1S1WW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
k59_171651_1	1117319.PSPO_20376	6.73e-12	76.6	COG3343@1|root,COG5183@1|root,COG3343@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,2Q202@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	AK	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
k59_63255_1	1165841.SULAR_05418	2.24e-131	384.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1Q55C@1224|Proteobacteria,42RCA@68525|delta/epsilon subdivisions,2YND3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	PPR
k59_76628_1	472759.Nhal_0093	4.09e-111	332.0	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1WVY7@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_124175_1	1121918.ARWE01000001_gene3104	1.66e-25	103.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,43TCG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_198946_1	1458357.BG58_25890	3.22e-62	217.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,Thioesterase
k59_117515_1	1165841.SULAR_01958	8.78e-101	306.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_56341_1	523791.Kkor_1351	1.02e-24	103.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XI9V@135619|Oceanospirillales	135619|Oceanospirillales	P	Sodium proton antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_56341_2	391615.ABSJ01000022_gene311	4.53e-14	70.9	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1J9WE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718	BPL_LplA_LipB
k59_49820_1	1121430.JMLG01000017_gene296	2.44e-52	181.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,2617T@186807|Peptococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_103926_1	1161401.ASJA01000003_gene2846	5.14e-12	62.8	COG3682@1|root,COG3682@2|Bacteria,1MZU3@1224|Proteobacteria,2UIN1@28211|Alphaproteobacteria,43Y9J@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_103926_2	926549.KI421517_gene3202	2.84e-29	117.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,47MV0@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_158168_1	1168067.JAGP01000001_gene767	1.64e-19	87.4	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,1RRFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63265_1	1165841.SULAR_00995	5.7e-128	367.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_192478_1	1121405.dsmv_3556	1.68e-89	276.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MJ1N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_16246_1	443144.GM21_1324	8.51e-11	61.6	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2WM7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Isocitrate dehydrogenase NADP-dependent, monomeric type	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_63725_1	1123228.AUIH01000003_gene939	5.24e-05	45.1	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XHBS@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_97793_1	983545.Glaag_0584	6.74e-18	88.2	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
k59_124655_1	335543.Sfum_2226	6.29e-55	193.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2MQCS@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	pbp2	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k59_63728_1	1168034.FH5T_07405	2.39e-71	238.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_144966_1	392500.Swoo_2749	2.91e-105	321.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,2QAK4@267890|Shewanellaceae	1236|Gammaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	GO:0000166,GO:0003674,GO:0003824,GO:0004066,GO:0004071,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006541,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016054,GO:0016211,GO:0016597,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0017076,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	iB21_1397.B21_00622,iECBD_1354.ECBD_2988,iECB_1328.ECB_00631,iECD_1391.ECD_00631,iEcHS_1320.EcHS_A0717,iEcolC_1368.EcolC_2982,iSF_1195.SF0619	Asn_synthase,GATase_7
k59_165213_1	1168289.AJKI01000036_gene3400	1.12e-44	159.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131445_1	395493.BegalDRAFT_3320	8.84e-56	187.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,46093@72273|Thiotrichales	72273|Thiotrichales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_97795_1	1123253.AUBD01000002_gene1275	6.54e-11	65.9	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_97795_2	1123257.AUFV01000003_gene1133	7.8e-60	192.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1X4ID@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_165214_1	387093.SUN_0481	2.12e-76	239.0	COG2951@1|root,COG2951@2|Bacteria,1PPIK@1224|Proteobacteria,43ABD@68525|delta/epsilon subdivisions,2YQXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_50337_1	1123053.AUDG01000008_gene3596	7.18e-08	53.9	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales	135613|Chromatiales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
k59_50337_2	1385517.N800_15240	4.73e-30	117.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1X3US@135614|Xanthomonadales	135614|Xanthomonadales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_84109_1	350058.Mvan_3615	5.85e-20	86.7	COG2813@1|root,COG2813@2|Bacteria,2I4F5@201174|Actinobacteria,234KU@1762|Mycobacteriaceae	201174|Actinobacteria	J	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_43246_1	1165841.SULAR_03208	1.68e-95	288.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2YM9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_118085_1	631362.Thi970DRAFT_01551	1.71e-20	90.5	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales	135613|Chromatiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_118085_2	1437448.AZRT01000037_gene3329	2.93e-05	48.1	COG3735@1|root,COG3735@2|Bacteria,1RBFT@1224|Proteobacteria,2U5YM@28211|Alphaproteobacteria,1J2GE@118882|Brucellaceae	28211|Alphaproteobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_111071_2	1122176.KB903532_gene2577	2.44e-15	72.8	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU1T@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
k59_172124_1	1148.1653058	2.05e-20	89.4	COG0376@1|root,COG0376@2|Bacteria,1G1NM@1117|Cyanobacteria,1H65X@1142|Synechocystis	1117|Cyanobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_36385_1	983545.Glaag_1670	9.78e-49	156.0	COG2944@1|root,COG2944@2|Bacteria,1N0M9@1224|Proteobacteria,1T0CA@1236|Gammaproteobacteria,46D0N@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	MqsA_antitoxin
k59_36385_2	28072.Nos7524_4000	3.32e-11	60.1	2C3PV@1|root,3307H@2|Bacteria,1GB76@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2834)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2834
k59_43249_1	2340.JV46_26430	4.17e-22	98.2	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1J4F9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM,TPR_19
k59_178717_2	1121346.KB899820_gene2758	1.02e-53	180.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,26SYT@186822|Paenibacillaceae	91061|Bacilli	L	Adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_144982_1	865937.Gilli_2202	8.42e-10	64.7	COG4447@1|root,COG4447@2|Bacteria,4PI0T@976|Bacteroidetes,1IG7E@117743|Flavobacteriia,2P756@244698|Gillisia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124672_1	1174528.JH992898_gene1303	1.13e-54	183.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G3DB@1117|Cyanobacteria	1117|Cyanobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
k59_50348_1	395493.BegalDRAFT_0559	4.7e-35	127.0	COG0457@1|root,COG0457@2|Bacteria,1R714@1224|Proteobacteria,1SA9Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165226_1	1165841.SULAR_01345	1.78e-144	434.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_84130_1	313596.RB2501_03535	4.13e-66	206.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_84130_2	1121875.KB907550_gene935	2.74e-30	116.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_22957_1	1123503.KB908056_gene1241	2.09e-42	148.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria,2KFVC@204458|Caulobacterales	204458|Caulobacterales	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k59_206118_1	1121895.Q765_08615	1.2e-06	52.4	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia,2NU08@237|Flavobacterium	976|Bacteroidetes	S	Cytochrome C oxidase assembly protein	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_45999_1	1121091.AUMP01000003_gene2870	7.44e-22	98.2	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli	91061|Bacilli	C	Glycolate oxidase	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
k59_52678_1	929562.Emtol_0552	6.07e-75	244.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47KUQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_147788_3	886377.Murru_0615	7.23e-14	72.4	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,1HWK3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
k59_134341_1	565045.NOR51B_2309	4.52e-49	173.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_38738_1	553385.JEMF01000022_gene3191	3.65e-19	91.7	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XISX@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein, tip-associated adhesin PilY1	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_5629_2	870187.Thini_0479	7.02e-74	229.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,460H1@72273|Thiotrichales	72273|Thiotrichales	P	Putrescine transport system permease	potH	-	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
k59_134342_1	1195246.AGRI_09700	7.55e-24	100.0	COG2856@1|root,COG2856@2|Bacteria,1PFUN@1224|Proteobacteria,1RR40@1236|Gammaproteobacteria,46AVB@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
k59_134342_2	1046724.KB889890_gene706	9.34e-20	83.6	COG1487@1|root,COG1487@2|Bacteria,1PUQF@1224|Proteobacteria,1TKAB@1236|Gammaproteobacteria,46BTX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
k59_188267_1	2340.JV46_05010	6.37e-69	225.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1J51F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_93606_1	395493.BegalDRAFT_3535	1.42e-98	295.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,4605M@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_100232_1	1121405.dsmv_2239	8.22e-50	166.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MIME@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k59_66484_1	572477.Alvin_1199	1.02e-67	223.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_113307_1	1165841.SULAR_04312	2.99e-89	266.0	COG2230@1|root,COG2230@2|Bacteria,1QZNI@1224|Proteobacteria,43CMD@68525|delta/epsilon subdivisions,2YTE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_147801_1	1121904.ARBP01000021_gene3616	8.91e-67	223.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_154349_1	983544.Lacal_0421	6.33e-49	177.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_134356_1	1051646.VITU9109_17658	4.29e-22	100.0	COG2984@1|root,COG2984@2|Bacteria,1NU5E@1224|Proteobacteria,1SJP9@1236|Gammaproteobacteria,1XWE3@135623|Vibrionales	135623|Vibrionales	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_25509_1	449447.MAE_59290	1.43e-90	270.0	2DM7C@1|root,3214Q@2|Bacteria,1GQS7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120805_1	1122194.AUHU01000002_gene2481	3.38e-15	69.3	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,468RS@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	cspD	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_120805_2	566466.NOR53_923	1.56e-44	147.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1J6Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_52705_1	1168034.FH5T_08640	1.62e-12	68.6	28NZ3@1|root,2ZBW2@2|Bacteria,4NN5U@976|Bacteroidetes,2FKZ5@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_52705_2	1168034.FH5T_08645	1.7e-22	94.7	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,2FT47@200643|Bacteroidia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_120808_1	240292.Ava_C0039	1.19e-54	173.0	COG0399@1|root,COG0399@2|Bacteria,1GDTU@1117|Cyanobacteria,1HSKF@1161|Nostocales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_195218_1	1121948.AUAC01000002_gene1127	5.65e-43	149.0	COG5403@1|root,COG5403@2|Bacteria,1N0H4@1224|Proteobacteria,2UFMN@28211|Alphaproteobacteria,43XNE@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
k59_113315_1	1165841.SULAR_03262	8.5e-37	135.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_113315_2	1165841.SULAR_03252	2.22e-21	92.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,42UIK@68525|delta/epsilon subdivisions,2YQ7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_140731_1	2340.JV46_28090	2.24e-108	325.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1J4E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0348 Polyferredoxin	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_93625_1	272134.KB731324_gene1426	2.65e-41	157.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD
k59_174764_1	1279017.AQYJ01000026_gene94	2.16e-15	75.9	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	crtF	-	2.1.1.210	ko:K09846	ko00906,ko01100,map00906,map01100	-	R07521,R07524,R07527,R07529,R07533,R07535	RC00003,RC02082	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_2
k59_6038_1	395493.BegalDRAFT_2105	5.84e-103	311.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,45ZYW@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_80227_2	1123518.ARWI01000001_gene880	3.26e-14	68.2	COG3609@1|root,COG3609@2|Bacteria,1N0MU@1224|Proteobacteria,1SAEQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	addiction module antidote protein	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
k59_113649_1	1396141.BATP01000022_gene387	2.35e-80	253.0	COG1215@1|root,COG1215@2|Bacteria,46SF7@74201|Verrucomicrobia,2ITZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_148283_1	1168034.FH5T_19470	5.34e-73	222.0	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,2FUCT@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
k59_215594_1	2340.JV46_17580	7.45e-91	281.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4KP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_175095_1	794903.OPIT5_19160	0.000156	50.1	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,CUB,Calx-beta,DUF3739,Haemagg_act,SdrD_B
k59_127686_1	1249627.D779_3331	9.79e-09	55.8	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S3WT@1236|Gammaproteobacteria,1WY7Z@135613|Chromatiales	135613|Chromatiales	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
k59_127686_2	395493.BegalDRAFT_0081	3.35e-26	103.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,460EX@72273|Thiotrichales	72273|Thiotrichales	KO	TIGRFAM Hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_181800_1	1165841.SULAR_04517	1.11e-74	227.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,42S9D@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_100657_1	631362.Thi970DRAFT_03247	2.38e-50	173.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1WWQM@135613|Chromatiales	135613|Chromatiales	P	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_168452_1	1280001.BAOA01000045_gene1668	1.3e-66	221.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1SM5A@1236|Gammaproteobacteria,1XVNU@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_161711_1	1121875.KB907547_gene3302	3e-62	197.0	COG3743@1|root,COG3743@2|Bacteria,4NQAU@976|Bacteroidetes,1I38D@117743|Flavobacteriia	976|Bacteroidetes	S	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141153_1	1307761.L21SP2_2030	2.17e-17	84.7	COG3666@1|root,COG3666@2|Bacteria,2J98U@203691|Spirochaetes	203691|Spirochaetes	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_168453_1	1144319.PMI16_02472	1.71e-11	60.1	COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,2VVRR@28216|Betaproteobacteria,4752E@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	acpM	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_168453_2	402881.Plav_1487	4.99e-43	152.0	COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,2U88A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_12381_1	1165841.SULAR_00205	1.59e-192	542.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2YMAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_154799_1	2340.JV46_03890	3.45e-39	144.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1JBY1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_154799_2	395493.BegalDRAFT_2957	3.62e-18	80.9	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,460TV@72273|Thiotrichales	72273|Thiotrichales	S	PFAM L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_46408_1	1394178.AWOO02000012_gene3741	2.45e-38	148.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4EHMT@85012|Streptosporangiales	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_39232_1	1229276.DI53_0414	3.92e-17	75.5	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
k59_39232_2	1168034.FH5T_04170	3.23e-94	305.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_60126_1	1245471.PCA10_19370	1.48e-68	230.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1YD1R@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_93978_1	631362.Thi970DRAFT_02016	4.6e-81	258.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales	135613|Chromatiales	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,RLAN,RimK
k59_215615_1	546268.NEISUBOT_04742	2.94e-17	88.6	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KPXZ@206351|Neisseriales	206351|Neisseriales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_148308_1	1165841.SULAR_10574	1.09e-58	188.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2YMNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_148308_2	1165841.SULAR_10569	5.56e-09	56.6	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2YN4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_121051_1	1239962.C943_00057	2.43e-25	109.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_19469_1	1173026.Glo7428_5010	9.66e-37	142.0	COG0500@1|root,COG0604@1|root,COG3321@1|root,COG0500@2|Bacteria,COG0604@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k59_12399_2	1288826.MSNKSG1_04681	1.1e-24	98.2	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria,4671I@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
k59_113683_1	335543.Sfum_2416	0.00029	43.1	COG1463@1|root,COG1463@2|Bacteria,1Q6ZU@1224|Proteobacteria,42RZ3@68525|delta/epsilon subdivisions,2WNF0@28221|Deltaproteobacteria,2MRII@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_113683_2	1049564.TevJSym_ad01540	1.77e-65	206.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1J5PY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	E COG1126 ABC-type polar amino acid transport system, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_46434_1	1288484.APCS01000046_gene107	4.86e-38	137.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_181831_1	1408444.JHYC01000021_gene13	3.09e-86	266.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1JD94@118969|Legionellales	118969|Legionellales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_168500_1	2340.JV46_10170	4.9e-77	238.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1J545@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iJN746.PP_4253	Cytochrome_CBB3,FixP_N
k59_1040_1	273075.Ta0344m	3.86e-17	82.0	COG2605@1|root,arCOG01030@2157|Archaea,2Y7BC@28890|Euryarchaeota,242B5@183967|Thermoplasmata	183967|Thermoplasmata	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_183985_1	83406.HDN1F_24710	8.53e-31	109.0	COG2002@1|root,COG2002@2|Bacteria,1NBUR@1224|Proteobacteria,1SSDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
k59_102752_1	926556.Echvi_1013	1.04e-59	202.0	COG0783@1|root,COG3039@1|root,COG0783@2|Bacteria,COG3039@2|Bacteria,4NI06@976|Bacteroidetes,47WK3@768503|Cytophagia	976|Bacteroidetes	LP	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_163701_1	313596.RB2501_02485	9.1e-68	216.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1I0Z6@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_163701_2	1107311.Q767_12210	2.72e-15	74.3	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,2NSRF@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_204334_1	1198232.CYCME_1844	1.01e-26	105.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,4611A@72273|Thiotrichales	72273|Thiotrichales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_204334_2	2340.JV46_10180	3.92e-20	83.2	2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,1SGKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55263_1	1528106.JRJE01000004_gene541	1.71e-26	107.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,2JS8P@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_62028_1	1177181.T9A_02468	1.23e-18	80.9	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XH9F@135619|Oceanospirillales	135619|Oceanospirillales	O	Alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_1046_1	383407.XOC_4041	3.4e-29	110.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,1RNQE@1236|Gammaproteobacteria,1X54N@135614|Xanthomonadales	135614|Xanthomonadales	C	NADH dehydrogenase NAD(P)H nitroreductase	-	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_1046_2	2340.JV46_05260	1.51e-146	422.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,1J515@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Flavocytochrome c sulphide dehydrogenase, flavin-binding	fccB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_211235_1	2340.JV46_16090	2.2e-136	409.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1J53A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475	ACT_4,HD_4,RelA_SpoT,TGS
k59_123039_1	1296415.JACC01000039_gene4040	1.42e-86	265.0	COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,1HWTG@117743|Flavobacteriia,2YM3E@290174|Aquimarina	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_204342_1	153948.NAL212_2209	5.21e-62	206.0	COG3211@1|root,COG3211@2|Bacteria,1NSHF@1224|Proteobacteria,2WGDG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_136533_1	1121904.ARBP01000005_gene4494	1.7e-64	217.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82421_1	1122603.ATVI01000006_gene625	1.21e-103	311.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1X4F0@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_211242_2	387093.SUN_1474	1.54e-42	145.0	COG1853@1|root,COG1853@2|Bacteria,1PD46@1224|Proteobacteria,42T15@68525|delta/epsilon subdivisions,2YPFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_1054_1	667014.Thein_0927	9.14e-80	253.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2GHHW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_177183_1	472759.Nhal_1283	1.09e-44	154.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_68820_1	1122621.ATZA01000030_gene2702	7.82e-29	119.0	COG0803@1|root,COG0803@2|Bacteria,4NHBN@976|Bacteroidetes,1IRG6@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_211244_1	870187.Thini_0272	1.2e-91	287.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales	72273|Thiotrichales	P	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
k59_14650_1	754476.Q7A_2836	3.74e-54	181.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,4602K@72273|Thiotrichales	72273|Thiotrichales	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_190937_1	1201290.M902_0860	1.08e-21	94.0	COG3631@1|root,COG3752@1|root,COG3631@2|Bacteria,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,42R9G@68525|delta/epsilon subdivisions,2WMTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_190937_2	1007104.SUS17_3848	2.37e-41	140.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,2K4FM@204457|Sphingomonadales	204457|Sphingomonadales	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_102781_1	1049564.TevJSym_bk00230	2.01e-121	364.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Alpha amylase catalytic	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_34881_1	1165841.SULAR_09629	1.89e-83	258.0	COG0025@1|root,COG0025@2|Bacteria,1QHRZ@1224|Proteobacteria,42RU2@68525|delta/epsilon subdivisions,2YPAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0025 NhaP-type Na H and K H	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	GGDEF,Na_H_Exchanger
k59_34881_2	1165841.SULAR_09634	7.77e-107	312.0	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,42ZIN@68525|delta/epsilon subdivisions,2YRQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	Thioredoxin_5
k59_34881_3	1165841.SULAR_09639	8.62e-131	392.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_109478_1	395493.BegalDRAFT_0200	1.54e-75	238.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HAMP,Response_reg,dCache_1
k59_34883_1	862908.BMS_2670	4.08e-05	44.3	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2MT7G@213481|Bdellovibrionales,2WQ23@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_34883_2	1165841.SULAR_01035	1.1e-49	176.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	2|Bacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_89321_1	272123.Anacy_0583	1.59e-14	69.7	COG1487@1|root,COG1487@2|Bacteria,1G6RD@1117|Cyanobacteria,1HSGC@1161|Nostocales	1117|Cyanobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
k59_7742_1	1165841.SULAR_03327	2.76e-87	264.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_21373_2	1265313.HRUBRA_01472	3.05e-20	89.4	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_28230_2	470145.BACCOP_03886	1.69e-09	61.6	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,2G2SA@200643|Bacteroidia,4AW3Q@815|Bacteroidaceae	976|Bacteroidetes	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.29,3.6.3.30,3.6.3.31	ko:K02010,ko:K02017,ko:K10112,ko:K11072	ko02010,map02010	M00189,M00190,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00299,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.10,3.A.1.11.1,3.A.1.8	-	-	ABC_tran,TOBE_2
k59_82446_1	1232683.ADIMK_0777	1.9e-63	210.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,46A4Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Aldehyde dehydrogenase family	xylC	-	1.2.1.28	ko:K00141	ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667	RC00075	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_75557_1	1165841.SULAR_04522	5.78e-94	280.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2YNK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_28233_1	1283300.ATXB01000001_gene2476	1.68e-111	325.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_28233_2	1283300.ATXB01000001_gene2477	1.85e-56	181.0	COG3415@1|root,COG3415@2|Bacteria,1QVAE@1224|Proteobacteria,1T533@1236|Gammaproteobacteria,1XGNF@135618|Methylococcales	135618|Methylococcales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_197742_1	387093.SUN_2375	2.49e-108	328.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2YRQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_89334_1	373994.Riv7116_3783	2.37e-34	130.0	COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,1HRAP@1161|Nostocales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_28235_1	55601.VANGNB10_cI0545	5.87e-05	42.7	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1XXSE@135623|Vibrionales	135623|Vibrionales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_28235_2	387093.SUN_1875	1.5e-50	162.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SJM@68525|delta/epsilon subdivisions,2YPJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_123068_1	1165841.SULAR_07128	1.07e-24	99.8	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2YMR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_123068_2	1165841.SULAR_07123	4.86e-89	271.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_48551_2	2340.JV46_06700	1.97e-95	289.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1J4C1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	histidyl-tRNA synthetase	hisS	GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358	HGTP_anticodon,tRNA-synt_His
k59_102798_1	218851.Aquca_019_00205.1	0.0	1052.0	COG0086@1|root,2QPYA@2759|Eukaryota,37HSD@33090|Viridiplantae,3GDVE@35493|Streptophyta	35493|Streptophyta	K	RNA polymerase	rpoC2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_102798_2	4155.Migut.D01338.1.p	6.33e-163	456.0	COG0052@1|root,KOG0832@2759|Eukaryota,37S1B@33090|Viridiplantae,3GHIA@35493|Streptophyta,44SIK@71274|asterids	35493|Streptophyta	J	Ribosomal protein S2	rps2	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_116377_1	1173023.KE650771_gene4342	4.09e-18	88.6	COG3240@1|root,COG4625@1|root,COG3240@2|Bacteria,COG4625@2|Bacteria,1G2WT@1117|Cyanobacteria,1JKJE@1189|Stigonemataceae	1117|Cyanobacteria	I	Autotransporter beta-domain	-	-	-	ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,Lipase_GDSL
k59_28237_1	1168034.FH5T_10115	2.64e-39	139.0	COG1052@1|root,COG1052@2|Bacteria,4NIHV@976|Bacteroidetes,2FPG0@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_28237_2	1168034.FH5T_10120	3.04e-37	130.0	2EVWW@1|root,33PAJ@2|Bacteria,4NZKD@976|Bacteroidetes,2FZQQ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75567_2	261292.Nit79A3_3464	3.31e-66	226.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase recycling family C-terminal	-	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N
k59_109498_1	883126.HMPREF9710_04198	2.15e-07	58.5	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,472HT@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_109498_2	176280.SE_1368	4.82e-15	81.3	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,4GXKP@90964|Staphylococcaceae	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
k59_150214_1	1219080.VEZ01S_05_01470	2.91e-90	289.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XUHS@135623|Vibrionales	135623|Vibrionales	S	transport system, fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_62079_1	466088.CL42_15305	2.66e-14	74.3	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,3NMZ7@468|Moraxellaceae	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
k59_28244_1	998674.ATTE01000001_gene3681	4.86e-06	46.6	2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria,46111@72273|Thiotrichales	72273|Thiotrichales	S	PFAM HopJ type III effector protein	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
k59_28244_2	2340.JV46_09620	2.77e-50	167.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1J9U3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	glxR	GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.1.1.411,1.1.1.60	ko:K00042,ko:K08319	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_1088_1	349521.HCH_03070	1.51e-96	290.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1XIG5@135619|Oceanospirillales	135619|Oceanospirillales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14686_1	1165841.SULAR_00120	4.58e-166	497.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_190961_1	545694.TREPR_1251	0.000242	45.4	COG0642@1|root,COG0642@2|Bacteria,2JBJB@203691|Spirochaetes	2|Bacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg,dCache_1
k59_117128_1	319003.Bra1253DRAFT_00080	2.6e-51	175.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,3JURJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_1841_1	395493.BegalDRAFT_1364	8.26e-09	62.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,45ZZC@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_29175_1	395493.BegalDRAFT_2044	3.36e-102	303.0	COG0618@1|root,COG0618@2|Bacteria,1MX0B@1224|Proteobacteria,1RMZ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0618 Exopolyphosphatase-related proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103639_2	1122599.AUGR01000023_gene4126	2.84e-31	116.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1XJAY@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_90197_2	572477.Alvin_3302	4.88e-14	75.1	COG5527@1|root,COG5527@2|Bacteria,1R7A6@1224|Proteobacteria,1RQMU@1236|Gammaproteobacteria,1X0XK@135613|Chromatiales	135613|Chromatiales	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
k59_130646_1	1165841.SULAR_05743	9.68e-27	103.0	COG0340@1|root,COG0340@2|Bacteria,1Q1NZ@1224|Proteobacteria,42RQM@68525|delta/epsilon subdivisions,2YP5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_130646_2	1165841.SULAR_05748	2.28e-48	162.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_191717_1	675814.VIC_004768	2.07e-34	132.0	COG4659@1|root,COG4660@1|root,COG4659@2|Bacteria,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1XT8E@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfE	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_117332_2	1165841.SULAR_01295	1.62e-40	137.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42T4D@68525|delta/epsilon subdivisions,2YPHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_56094_1	1125863.JAFN01000001_gene1312	5.2e-54	186.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,42MYY@68525|delta/epsilon subdivisions,2WJ6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SpoVR family protein	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_76411_1	349124.Hhal_1183	3.15e-09	55.5	2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SX58@1236|Gammaproteobacteria,1WZBH@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM TIGR02449 family protein	-	-	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	-
k59_76411_2	1123393.KB891316_gene2117	2.98e-18	80.1	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VVSV@28216|Betaproteobacteria,1KT6K@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Cell division protein ZapA	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_191719_1	215803.DB30_5190	9.39e-18	82.4	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,437GH@68525|delta/epsilon subdivisions,2X2P4@28221|Deltaproteobacteria,2YU9N@29|Myxococcales	28221|Deltaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_49521_1	1173028.ANKO01000250_gene2343	2.02e-98	295.0	COG1215@1|root,COG1215@2|Bacteria,1G2NN@1117|Cyanobacteria,1H8F0@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_205278_1	335543.Sfum_1617	7.12e-11	63.5	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_205278_2	10228.TriadP23574	2.39e-06	56.2	COG0457@1|root,KOG1124@2759|Eukaryota,38F8U@33154|Opisthokonta,3BAQE@33208|Metazoa	33208|Metazoa	S	Transmembrane and	TMTC1	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_137403_1	395493.BegalDRAFT_2591	1.35e-99	300.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,460SY@72273|Thiotrichales	72273|Thiotrichales	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_191729_1	2340.JV46_04100	3.63e-33	121.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1J6NP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
k59_191729_2	747.DR93_1094	8.45e-36	123.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1Y8WG@135625|Pasteurellales	135625|Pasteurellales	C	Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_63028_1	1165841.SULAR_00135	4.59e-103	318.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_157964_1	387093.SUN_0555	9.55e-118	354.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_76418_1	1121935.AQXX01000093_gene3409	3.41e-08	54.7	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria,1XI2E@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD1	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_76418_2	1163617.SCD_n00183	4e-41	146.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_178032_1	709991.Odosp_2222	2.41e-56	189.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,2FSFF@200643|Bacteroidia,22ZCX@171551|Porphyromonadaceae	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_123897_1	713587.THITH_08960	1.53e-93	286.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_123897_2	2340.JV46_23640	7.63e-15	73.9	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_69787_1	1167006.UWK_01356	1.3e-40	156.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,42TR0@68525|delta/epsilon subdivisions,2WQ94@28221|Deltaproteobacteria,2MQ09@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_hydro_8,Glyco_trans_2_3,Glycos_transf_2,PilZ
k59_35726_2	395493.BegalDRAFT_2859	4.94e-76	263.0	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_171445_1	566466.NOR53_428	2.9e-186	524.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1J5DE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_35728_1	395493.BegalDRAFT_0387	8.23e-58	200.0	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,1MX2X@1224|Proteobacteria,1RY8H@1236|Gammaproteobacteria,4625Z@72273|Thiotrichales	72273|Thiotrichales	Q	methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25
k59_130672_1	1168034.FH5T_03830	1.93e-87	264.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_198678_1	1265505.ATUG01000001_gene4053	4.9e-10	65.5	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1R91W@1224|Proteobacteria,42PXP@68525|delta/epsilon subdivisions,2WJJX@28221|Deltaproteobacteria,2MJ2Z@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_9
k59_151050_1	1313301.AUGC01000010_gene983	9.04e-06	44.3	2DTS4@1|root,33MFD@2|Bacteria,4NZQB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_205297_1	1168034.FH5T_03110	2e-27	102.0	COG4109@1|root,COG4109@2|Bacteria,4NTDQ@976|Bacteroidetes,2FTXG@200643|Bacteroidia	976|Bacteroidetes	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
k59_205297_2	1168034.FH5T_03105	2.15e-54	173.0	COG2172@1|root,COG2172@2|Bacteria,4NRAS@976|Bacteroidetes,2FT57@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2
k59_8601_1	566466.NOR53_2675	1.95e-71	229.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria,1J8KH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_171455_1	1165841.SULAR_04302	4.59e-209	593.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_137432_1	1227457.C451_04913	9.7e-10	65.9	COG2304@1|root,arCOG07611@1|root,arCOG02902@2157|Archaea,arCOG07611@2157|Archaea,2Y8GQ@28890|Euryarchaeota	28890|Euryarchaeota	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
k59_49543_2	1123325.JHUV01000016_gene176	5.47e-64	213.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56115_1	765914.ThisiDRAFT_0073	8.81e-17	81.6	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_15568_2	1028800.RG540_PA10390	1.63e-65	213.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,4BDDJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_164587_1	1168034.FH5T_04080	1.87e-77	256.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_212117_1	194699.Q774Z7_BPBPP	2.12e-23	92.0	4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses  no RNA stage,4QPH6@28883|Caudovirales,4QNEM@10744|Podoviridae	10744|Podoviridae	S	Protein of unknwon function (DUF3310)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212117_6	637389.Acaty_c1775	8.78e-13	65.5	COG1734@1|root,COG1734@2|Bacteria,1PUIF@1224|Proteobacteria,1T8U8@1236|Gammaproteobacteria,2NDF8@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_42532_1	1165841.SULAR_02068	8.43e-106	312.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2YNC5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_130692_1	1168034.FH5T_06525	2.86e-126	385.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_184946_1	1191523.MROS_1652	1.53e-63	203.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,TAT_signal
k59_49563_1	1165841.SULAR_05968	5.64e-100	299.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,43BHX@68525|delta/epsilon subdivisions,2YMEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_191763_1	469610.HMPREF0189_01976	6.47e-12	69.3	COG1484@1|root,COG1484@2|Bacteria,1MZNW@1224|Proteobacteria,2VUAM@28216|Betaproteobacteria	28216|Betaproteobacteria	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
k59_205334_1	1168034.FH5T_06025	8.9e-117	339.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,2FN7D@200643|Bacteroidia	976|Bacteroidetes	G	Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
k59_76456_1	1312959.KI914701_gene2876	3.76e-26	100.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,1W9G6@1268|Micrococcaceae	201174|Actinobacteria	CO	Belongs to the thioredoxin family	trxA	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
k59_144168_1	1121405.dsmv_0665	6.74e-58	199.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_8633_1	1165841.SULAR_09119	4.66e-115	347.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_184952_1	2340.JV46_26640	8.75e-106	337.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_90268_1	388051.AUFE01000035_gene4020	7.55e-62	206.0	COG4653@1|root,COG4653@2|Bacteria	2|Bacteria	G	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_capsid
k59_103717_1	1168034.FH5T_17375	1.81e-89	275.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
k59_151565_2	1165841.SULAR_06398	3.98e-45	153.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_16020_2	395493.BegalDRAFT_0843	5.58e-98	288.0	COG4636@1|root,COG4636@2|Bacteria,1R58B@1224|Proteobacteria,1RSKS@1236|Gammaproteobacteria,4637Z@72273|Thiotrichales	72273|Thiotrichales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_158408_1	1121875.KB907546_gene2218	9.1e-45	159.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,1HWZ5@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23
k59_2542_2	1165841.SULAR_04437	5.93e-39	133.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065	OstA
k59_165007_1	595460.RRSWK_01941	5.95e-44	155.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_56606_1	1168034.FH5T_04325	2.25e-67	206.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,2FS0P@200643|Bacteroidia	976|Bacteroidetes	L	COG NOG19098 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
k59_137956_1	387093.SUN_0422	1.88e-31	112.0	2BQJ4@1|root,32JEZ@2|Bacteria,1Q29Y@1224|Proteobacteria,42V8X@68525|delta/epsilon subdivisions,2YQIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_137956_2	1165841.SULAR_09339	2.09e-93	277.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_171924_1	1165841.SULAR_10024	5.7e-39	134.0	COG5456@1|root,COG5456@2|Bacteria	2|Bacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_158410_1	2340.JV46_05350	2.27e-27	104.0	COG3439@1|root,COG3439@2|Bacteria,1NDCV@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_158410_2	661367.LLO_2343	3.04e-22	93.2	COG1376@1|root,COG1376@2|Bacteria,1RDA8@1224|Proteobacteria,1S4PD@1236|Gammaproteobacteria,1JCVH@118969|Legionellales	118969|Legionellales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_104191_1	393595.ABO_1841	2.34e-56	180.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1XJSV@135619|Oceanospirillales	135619|Oceanospirillales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_192262_1	1121459.AQXE01000005_gene1537	3.35e-07	58.5	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2M8IF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_141097_1	269482.Bcep1808_5897	1.66e-12	72.8	COG0789@1|root,COG0789@2|Bacteria,1RFQI@1224|Proteobacteria,2VS80@28216|Betaproteobacteria,1K7HC@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_25909_1	717231.Flexsi_0145	3.58e-13	63.5	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
k59_168374_1	1267533.KB906737_gene1663	1.88e-08	57.0	COG3299@1|root,COG3299@2|Bacteria,3Y45Q@57723|Acidobacteria,2JI3P@204432|Acidobacteriia	204432|Acidobacteriia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_168374_2	373994.Riv7116_5196	1.82e-17	84.0	COG3292@1|root,COG3299@1|root,COG4447@1|root,COG3292@2|Bacteria,COG3299@2|Bacteria,COG4447@2|Bacteria,1G6U3@1117|Cyanobacteria,1HQRU@1161|Nostocales	1117|Cyanobacteria	T	protein, phage tail-like region	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,Sortilin-Vps10
k59_202227_2	665032.C9DG24_9CAUD	6.18e-13	70.5	4QEE7@10239|Viruses,4QV59@35237|dsDNA viruses  no RNA stage,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53036_1	349521.HCH_02430	8.38e-90	274.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XH6T@135619|Oceanospirillales	135619|Oceanospirillales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_32869_1	384765.SIAM614_17164	2.58e-116	347.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_32869_2	1123247.AUIJ01000001_gene1730	1.98e-54	186.0	COG4665@1|root,COG4665@2|Bacteria,1QZG7@1224|Proteobacteria,2U0WE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_154737_1	472759.Nhal_2320	2.02e-116	335.0	COG0288@1|root,COG0288@2|Bacteria,1R979@1224|Proteobacteria,1RS85@1236|Gammaproteobacteria,1X075@135613|Chromatiales	135613|Chromatiales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_134626_1	335283.Neut_2171	4.9e-65	210.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,371VW@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_127657_1	1165841.SULAR_04282	8.65e-115	334.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2YMJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_209059_1	330214.NIDE0577	4.17e-12	72.4	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
k59_66850_1	1112274.KI911560_gene923	2.22e-107	326.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,2VJHS@28216|Betaproteobacteria,2KKQ9@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM sulfatase	-	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_113616_1	247634.GPB2148_2801	5.17e-102	312.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_9
k59_161678_1	7668.SPU_010256-tr	1.8e-36	139.0	KOG1075@1|root,KOG1075@2759|Eukaryota	7668.SPU_010256-tr|-	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_195551_1	2340.JV46_23640	1.94e-146	453.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_25934_1	1165841.SULAR_05183	9.3e-174	509.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_19423_1	202952.BBLI01000015_gene1343	5.32e-09	65.9	COG4974@1|root,COG4974@2|Bacteria,1QUFQ@1224|Proteobacteria,1T1XD@1236|Gammaproteobacteria,3NN1Z@468|Moraxellaceae	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k59_209075_1	1408473.JHXO01000001_gene2095	2.13e-140	404.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,2FNZB@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_161683_1	1165841.SULAR_01445	3.02e-170	484.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DEAD DEAH box helicase	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_168409_1	326298.Suden_0222	2.94e-81	256.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2YN29@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_154757_1	879212.DespoDRAFT_02234	1.97e-12	65.9	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_154757_2	879212.DespoDRAFT_02234	4.9e-79	244.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_107728_1	1165841.SULAR_00230	1.63e-67	221.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_39194_1	349520.PPE_04324	1.36e-31	122.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli,26TD7@186822|Paenibacillaceae	91061|Bacilli	S	glycosyl transferase family 2	galnac-T15	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
k59_39194_2	1250278.JQNQ01000001_gene1434	1.04e-37	138.0	COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,1HY83@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_53060_1	329726.AM1_6085	4.71e-31	126.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria	1117|Cyanobacteria	K	ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_127674_1	631362.Thi970DRAFT_01926	4.99e-30	108.0	2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,1SBDA@1236|Gammaproteobacteria,1WZ0Q@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148274_2	1268622.AVS7_00217	1.17e-27	110.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,2VICY@28216|Betaproteobacteria,4AD86@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_32911_1	395493.BegalDRAFT_0392	9.42e-64	213.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	twitching motility protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_107738_1	1165841.SULAR_00585	7.9e-132	377.0	COG0596@1|root,COG0596@2|Bacteria,1NH3R@1224|Proteobacteria,42R8Q@68525|delta/epsilon subdivisions,2YNWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_25958_1	1123059.KB823013_gene469	9.83e-108	335.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,43W9Q@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_113641_1	555500.I215_15140	2.9e-09	57.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1HX18@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_113641_2	484018.BACPLE_00801	1.4e-08	57.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,2FPV4@200643|Bacteroidia,4AM8G@815|Bacteroidaceae	976|Bacteroidetes	T	COG0589 Universal stress protein UspA and related nucleotide-binding	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
k59_93948_1	105559.Nwat_1442	6.77e-86	268.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0324	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_93948_2	1266925.JHVX01000006_gene2180	2.87e-06	46.2	arCOG10395@1|root,33G89@2|Bacteria,1NN4G@1224|Proteobacteria,2WE4F@28216|Betaproteobacteria,374BQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Family of unknown function (DUF5395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5395
k59_195574_1	1168034.FH5T_05590	2.81e-127	388.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,2FN1R@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_209105_1	1121451.DESAM_21142	3.36e-37	141.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,42QFG@68525|delta/epsilon subdivisions,2WK91@28221|Deltaproteobacteria,2MGCW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_175090_1	396588.Tgr7_0237	1.49e-12	68.9	COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1SCSU@1236|Gammaproteobacteria,1WZQA@135613|Chromatiales	135613|Chromatiales	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k59_181792_1	1122604.JONR01000031_gene1284	1.39e-12	67.0	COG1418@1|root,COG1418@2|Bacteria,1RGE5@1224|Proteobacteria,1SSYD@1236|Gammaproteobacteria,1XDF6@135614|Xanthomonadales	135614|Xanthomonadales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148281_1	653733.Selin_1711	4.88e-34	117.0	COG1813@1|root,COG1813@2|Bacteria	2|Bacteria	K	peptidyl-tyrosine sulfation	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
k59_202278_1	349521.HCH_02561	5.07e-21	97.1	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1XMX0@135619|Oceanospirillales	135619|Oceanospirillales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_209106_1	1121875.KB907546_gene2199	2.27e-86	272.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_73323_2	1121405.dsmv_3498	7.85e-30	113.0	2AIMV@1|root,31947@2|Bacteria,1Q1RW@1224|Proteobacteria,42U9F@68525|delta/epsilon subdivisions,2WQ95@28221|Deltaproteobacteria,2MKIY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
k59_12747_3	1174528.JH992893_gene5682	2.27e-07	50.1	COG3251@1|root,COG3251@2|Bacteria	2|Bacteria	P	PFAM MbtH domain protein	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	CBF_beta,MbtH
k59_12755_1	575540.Isop_0706	2.82e-17	86.3	COG1404@1|root,COG1404@2|Bacteria,2IZ64@203682|Planctomycetes	203682|Planctomycetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_26454_1	1168034.FH5T_21310	1.17e-116	357.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,2FMX0@200643|Bacteroidia	976|Bacteroidetes	D	FtsK SpoIIIE family protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_6323_1	395493.BegalDRAFT_0701	2.46e-67	222.0	2AK75@1|root,31AXA@2|Bacteria,1PPBJ@1224|Proteobacteria,1SH0P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_215941_1	75379.Tint_0957	4.09e-42	154.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KJ32@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE1	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_6325_1	1168034.FH5T_17425	6.16e-118	347.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_182168_1	768671.ThimaDRAFT_4484	6.62e-119	353.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1Q7PK@1224|Proteobacteria,1RSF0@1236|Gammaproteobacteria,1WWA3@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
k59_33256_1	1165841.SULAR_07395	4.28e-100	297.0	COG0642@1|root,COG2205@2|Bacteria,1R5ZF@1224|Proteobacteria,43CBR@68525|delta/epsilon subdivisions,2YTBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_209407_1	665956.HMPREF1032_01027	3.39e-08	60.8	COG3754@1|root,COG3754@2|Bacteria,1UIQ8@1239|Firmicutes,25FGI@186801|Clostridia,3WJB0@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX
k59_94315_1	1168034.FH5T_10830	3.25e-95	280.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_12766_1	1157943.KB892705_gene884	1.14e-56	190.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,233IZ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_80585_1	768671.ThimaDRAFT_2982	8.15e-82	249.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1X0WW@135613|Chromatiales	135613|Chromatiales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_80585_2	882378.RBRH_02088	2.32e-16	79.0	COG1024@1|root,COG1024@2|Bacteria,1R75Q@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01825,ko:K07516,ko:K13816	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko02024,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map02024	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_53462_1	1123514.KB905899_gene1933	2.98e-106	315.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_121439_1	314230.DSM3645_09257	6.17e-32	127.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2IX1D@203682|Planctomycetes	203682|Planctomycetes	H	May be the GTPase, regulating ATP sulfurylase activity	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
k59_67278_1	1089547.KB913013_gene3056	5.05e-25	102.0	COG0607@1|root,COG3118@1|root,COG0607@2|Bacteria,COG3118@2|Bacteria,4NUPH@976|Bacteroidetes,47PJB@768503|Cytophagia	976|Bacteroidetes	OP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
k59_33263_1	497964.CfE428DRAFT_6362	7.04e-54	182.0	COG1146@1|root,COG1146@2|Bacteria,46TI2@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_19773_1	1121324.CLIT_5c00880	1.7e-84	257.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia	1239|Firmicutes	S	Threonyl alanyl tRNA synthetase SAD	-	-	6.1.1.7	ko:K01872,ko:K07050	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
k59_19773_2	290318.Cvib_0387	3.28e-18	82.0	COG2094@1|root,COG2094@2|Bacteria,1FDYR@1090|Chlorobi	1090|Chlorobi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
k59_195860_1	1499967.BAYZ01000061_gene5966	4.77e-91	293.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	wspE	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3,2.7.7.65	ko:K03407,ko:K11444,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_215961_1	1165841.SULAR_01125	1.76e-75	226.0	2BYFY@1|root,33EM6@2|Bacteria,1NIAK@1224|Proteobacteria,432Y1@68525|delta/epsilon subdivisions,2YSQQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83090_1	589873.EP13_03130	2.32e-38	145.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	tolC	GO:0002790,GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0010033,GO:0014070,GO:0015031,GO:0015075,GO:0015267,GO:0015288,GO:0015318,GO:0015562,GO:0015688,GO:0015711,GO:0015833,GO:0015850,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042886,GO:0042930,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0046618,GO:0046903,GO:0047485,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:1901678,GO:1902495,GO:1990195,GO:1990196,GO:1990281,GO:1990351	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	iAPECO1_1312.APECO1_3378,iEC042_1314.EC042_3326,iECOK1_1307.ECOK1_3463	OEP
k59_62679_1	1165841.SULAR_00360	1.64e-105	318.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_1644_2	1267535.KB906767_gene4444	5.62e-09	58.9	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_15180_1	105559.Nwat_0547	2.19e-94	303.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales	135613|Chromatiales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_143743_1	530564.Psta_2699	9.07e-16	85.5	COG1874@1|root,COG2304@1|root,COG1874@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
k59_103293_1	876044.IMCC3088_1003	3.45e-20	90.1	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1J4VG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1509 Lysine 2,3-aminomutase	epmB	GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569	Fer4_12,Fer4_14,Radical_SAM
k59_184550_1	2340.JV46_07220	3.25e-85	255.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1J5Q4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_55839_1	1297742.A176_05102	1.86e-17	87.4	COG2850@1|root,COG2850@2|Bacteria	2|Bacteria	P	peptidyl-arginine hydroxylation	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
k59_204875_1	1123054.KB907748_gene3425	4.19e-125	365.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1X0JE@135613|Chromatiales	135613|Chromatiales	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_35347_1	1165841.SULAR_04157	3.99e-145	417.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_35347_2	1165841.SULAR_04167	3.29e-71	228.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2YMS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_184551_1	754436.JCM19237_32	6.54e-05	43.9	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XSXY@135623|Vibrionales	135623|Vibrionales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_184551_2	2340.JV46_22290	6.34e-82	250.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1J4DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Mg2 and Co2 transporter CorC	corC	GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_21896_1	933262.AXAM01000072_gene2248	1.95e-23	92.0	2E1B7@1|root,32WR3@2|Bacteria,1N4JM@1224|Proteobacteria,42Y3K@68525|delta/epsilon subdivisions,2WTEN@28221|Deltaproteobacteria,2MNM6@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_21896_2	1229172.JQFA01000004_gene983	4.62e-05	44.7	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
k59_110101_1	1165841.SULAR_09979	5.16e-107	322.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,430CZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_55844_1	1048983.EL17_12710	5.86e-54	186.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47MAI@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_157501_1	688270.Celal_1053	1.24e-39	140.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia,1F863@104264|Cellulophaga	976|Bacteroidetes	S	COGs COG1853 Conserved protein domain typically associated with flavoprotein oxygenase DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_42182_1	95619.PM1_0220975	7.45e-15	78.2	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria,1R4WG@1224|Proteobacteria,1T1FC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	oprF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,OprF,TSP_3
k59_69394_1	397945.Aave_3355	8.26e-98	311.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VMB0@28216|Betaproteobacteria,4ABB8@80864|Comamonadaceae	28216|Betaproteobacteria	L	Type I restriction enzyme R protein N terminus (HSDR_N)	hsdR-1	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,ResIII
k59_204879_1	83406.HDN1F_27670	5.05e-82	263.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1J4MV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
k59_49108_1	2340.JV46_24900	1.01e-122	360.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1J5D4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	O-acetylhomoserine sulfhydrylase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	iJN746.PP_2528	Cys_Met_Meta_PP
k59_89843_1	28229.ND2E_1481	7.59e-32	119.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,2Q728@267889|Colwelliaceae	1236|Gammaproteobacteria	D	Maf-like protein	yhdE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_171058_1	525897.Dbac_2138	3.9e-54	188.0	COG3437@1|root,COG3437@2|Bacteria,1PZ2F@1224|Proteobacteria,42Q4C@68525|delta/epsilon subdivisions,2WM32@28221|Deltaproteobacteria,2MEND@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_15211_1	1150600.ADIARSV_2564	1e-15	78.6	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1ISDY@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DUF3887,Hydrolase_4
k59_15211_2	313596.RB2501_01975	1.1e-19	89.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_184567_1	501479.ACNW01000062_gene2740	3.34e-70	229.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_1670_1	999541.bgla_2g10690	3.49e-08	62.4	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,1JZUU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	amino acid adenylation domain protein	-	-	-	ko:K04780	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_116992_1	562743.JH976442_gene678	2.42e-42	149.0	COG2227@1|root,COG2227@2|Bacteria,1UXZZ@1239|Firmicutes,4HG9W@91061|Bacilli	91061|Bacilli	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_21919_1	1165841.SULAR_02883	1.78e-123	364.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_157520_1	1163617.SCD_n00435	4.59e-24	102.0	COG0515@1|root,COG1639@1|root,COG2203@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HDOD,Pkinase
k59_157520_2	2340.JV46_16980	2.74e-12	63.2	COG3118@1|root,COG3118@2|Bacteria,1RI6E@1224|Proteobacteria,1S8B4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	Thioredoxin
k59_184576_1	1335757.SPICUR_05145	8.78e-15	76.3	COG1794@1|root,COG1794@2|Bacteria,1QEFX@1224|Proteobacteria,1S0ER@1236|Gammaproteobacteria,1WZJN@135613|Chromatiales	135613|Chromatiales	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_49128_1	2340.JV46_13510	4.7e-34	123.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S9PP@1236|Gammaproteobacteria,1J6J0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_49128_2	768671.ThimaDRAFT_4369	4.11e-23	95.9	COG1432@1|root,COG1432@2|Bacteria,1PC2I@1224|Proteobacteria,1TIXS@1236|Gammaproteobacteria,1WXAE@135613|Chromatiales	135613|Chromatiales	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k59_117002_1	391615.ABSJ01000041_gene70	2.85e-60	192.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1J4ZS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_117002_2	1380380.JIAX01000014_gene2741	1.55e-11	64.3	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_137136_1	1294143.H681_14065	4.31e-69	228.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GAF_2,GGDEF,HTH_8,Sigma54_activat,V4R,XylR_N
k59_62725_1	1165841.SULAR_05563	1.12e-60	196.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2YMD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	2-nitropropane dioxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_62725_2	1165841.SULAR_05558	2.09e-62	203.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_149117_1	1408428.JNJP01000004_gene2881	1.17e-83	260.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
k59_94892_1	571166.KI421509_gene2083	2.62e-93	296.0	COG2931@1|root,COG2931@2|Bacteria,1QX4P@1224|Proteobacteria,2U0QK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PAP2
k59_33895_1	1165841.SULAR_00815	6.14e-113	328.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2YP9T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
k59_13559_2	98439.AJLL01000075_gene887	7.47e-15	69.7	2AGP1@1|root,316WK@2|Bacteria,1GKU8@1117|Cyanobacteria,1JMR8@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169455_1	631362.Thi970DRAFT_01984	1.22e-28	112.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,1RQES@1236|Gammaproteobacteria,1WXQ1@135613|Chromatiales	135613|Chromatiales	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
k59_169455_2	1123400.KB904747_gene553	3.87e-39	133.0	COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,462NI@72273|Thiotrichales	72273|Thiotrichales	S	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_122007_1	2340.JV46_09700	2.65e-46	156.0	COG3448@1|root,COG3448@2|Bacteria,1QUQ5@1224|Proteobacteria,1T20R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_196567_1	278963.ATWD01000001_gene3942	3.25e-67	214.0	COG0175@1|root,COG0175@2|Bacteria,3Y36I@57723|Acidobacteria,2JHYJ@204432|Acidobacteriia	204432|Acidobacteriia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_203349_1	324925.Ppha_2399	2.62e-05	47.8	COG1012@1|root,COG1012@2|Bacteria,1FDHS@1090|Chlorobi	1090|Chlorobi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_122010_1	225937.HP15_373	5.94e-44	159.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,464QF@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_122010_2	1298865.H978DRAFT_3835	2.53e-46	152.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,46787@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_122010_3	2340.JV46_16140	1.24e-34	122.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1J5V2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_54238_1	95619.PM1_0209865	1.86e-34	126.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_94898_1	1296416.JACB01000026_gene3952	6.51e-05	50.4	COG1858@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG5276@1|root,COG1858@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,COG5276@2|Bacteria,4NIPP@976|Bacteroidetes,1I7A8@117743|Flavobacteriia,2YKAC@290174|Aquimarina	976|Bacteroidetes	MP	Cellulose binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_3,Cytochrom_C,Cytochrom_D1,PKD
k59_101680_1	756067.MicvaDRAFT_4927	3.7e-61	212.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_61014_1	1564096.A0A0A0YRA9_9CAUD	1.93e-19	97.4	4QEE7@10239|Viruses,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189798_1	765911.Thivi_0919	1.5e-39	139.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1WX2M@135613|Chromatiales	135613|Chromatiales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_189798_2	1380387.JADM01000021_gene1656	2.96e-06	51.6	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XIW5@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM,TPR_19
k59_155913_1	929558.SMGD1_0923	0.000713	42.4	COG5001@1|root,COG5001@2|Bacteria,1QVXB@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_88130_1	118168.MC7420_879	4.59e-44	161.0	COG0515@1|root,COG1672@1|root,COG0515@2|Bacteria,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria,1H73P@1150|Oscillatoriales	1117|Cyanobacteria	KLT	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_35,CHAT,Pkinase,TIR_2
k59_88133_1	616991.JPOO01000001_gene3787	3.57e-86	268.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia,23GT1@178469|Arenibacter	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_203363_1	411459.RUMOBE_01293	8.7e-37	132.0	2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,254MP@186801|Clostridia,3Y083@572511|Blautia	186801|Clostridia	S	COG NOG38524 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169475_1	2340.JV46_27980	2.57e-20	82.8	2EHQ5@1|root,33BFX@2|Bacteria,1NJW1@1224|Proteobacteria,1SHMS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
k59_169475_2	2340.JV46_28000	1.86e-75	233.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1J545@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_61016_1	314275.MADE_1008335	1.73e-79	240.0	COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria,46742@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Phosphoribosyl transferase domain	hpt	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_74580_1	234267.Acid_7625	1.58e-45	156.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
k59_122034_1	49964.Q94MS4_9CAUD	1.04e-44	167.0	4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses  no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210135_1	1165841.SULAR_06998	1.14e-86	260.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2YNZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_158898_1	1168034.FH5T_12215	1.78e-49	167.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,2FPDM@200643|Bacteroidia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_158898_2	1168034.FH5T_12220	8.98e-14	69.7	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_84516_1	1165841.SULAR_08247	2.9e-47	172.0	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36674_1	1517681.HW45_25615	5.49e-27	113.0	COG3659@1|root,COG3659@2|Bacteria,1R8TI@1224|Proteobacteria,1S21B@1236|Gammaproteobacteria,1XVR4@135623|Vibrionales	135623|Vibrionales	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
k59_192813_1	929712.KI912613_gene106	8.33e-14	73.9	COG1309@1|root,COG1309@2|Bacteria,2IB4X@201174|Actinobacteria,4CSQ6@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_152129_1	926559.JoomaDRAFT_3386	5.13e-07	56.2	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,1HX5V@117743|Flavobacteriia	976|Bacteroidetes	HQ	Isochorismate synthase	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
k59_3194_1	1144305.PMI02_04751	2.42e-78	253.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_30326_2	1219077.VAZ01S_048_00240	2.99e-67	211.0	COG3208@1|root,COG3208@2|Bacteria,1R0QV@1224|Proteobacteria,1T4NZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192815_1	650150.ERH_1520	9.56e-14	76.6	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,3VNZD@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Psort location Cytoplasmic, score 8.87	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_10,Mur_ligase_C,Mur_ligase_M
k59_64027_1	1165841.SULAR_02498	1.17e-78	238.0	COG1309@1|root,COG1309@2|Bacteria,1R53F@1224|Proteobacteria,42T25@68525|delta/epsilon subdivisions,2YPFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_111376_1	748247.AZKH_3053	5.17e-69	225.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,2KUBM@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_30332_1	1123368.AUIS01000007_gene2681	5.68e-107	333.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,2NCDM@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_131797_2	1408473.JHXO01000011_gene3054	2.9e-74	224.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,2FN4T@200643|Bacteroidia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_172496_1	1158756.AQXQ01000012_gene1688	2.5e-16	79.7	COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAES@1236|Gammaproteobacteria,1WZM3@135613|Chromatiales	135613|Chromatiales	O	DNA-J related protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DnaJ
k59_91215_1	378806.STAUR_6538	4.09e-43	157.0	COG0304@1|root,COG0304@2|Bacteria,1Q3B2@1224|Proteobacteria,43927@68525|delta/epsilon subdivisions,2X47V@28221|Deltaproteobacteria,2YYFV@29|Myxococcales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_131801_1	644968.DFW101_1208	4.7e-37	135.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,42QZX@68525|delta/epsilon subdivisions,2WN5T@28221|Deltaproteobacteria,2MA07@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
k59_104741_1	2340.JV46_27610	3.4e-48	160.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1J4EE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_43508_1	177437.HRM2_45430	1.54e-36	130.0	COG1176@1|root,COG1176@2|Bacteria,1MW9Y@1224|Proteobacteria,42N6W@68525|delta/epsilon subdivisions,2WM70@28221|Deltaproteobacteria,2MN5U@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k59_43508_2	177437.HRM2_45420	2.55e-64	204.0	COG1177@1|root,COG1177@2|Bacteria,1MWVC@1224|Proteobacteria,42PRM@68525|delta/epsilon subdivisions,2WM44@28221|Deltaproteobacteria,2MN3J@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k59_152149_1	1095769.CAHF01000022_gene432	1.21e-49	186.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_91218_1	1284352.AOIG01000012_gene1528	0.00071	50.1	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,4HB5X@91061|Bacilli,26RVA@186822|Paenibacillaceae	91061|Bacilli	G	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate	yulC	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_104745_2	1121937.AUHJ01000002_gene3402	1.56e-48	159.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,465GT@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	crp	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,cNMP_binding
k59_185944_1	749222.Nitsa_1851	6.4e-07	50.1	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_185944_2	1165841.SULAR_09869	5.85e-58	187.0	COG1426@1|root,COG1426@2|Bacteria,1QT7G@1224|Proteobacteria,42XGH@68525|delta/epsilon subdivisions,2YQZ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213129_1	1121403.AUCV01000004_gene2051	7.95e-06	47.4	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2WRW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YkuD
k59_213129_2	1165841.SULAR_00015	1.37e-64	210.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2YNFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_36695_1	1165841.SULAR_04898	1.71e-118	343.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_213130_2	400682.PAC_15715252	1.61e-05	49.7	KOG2177@1|root,KOG2177@2759|Eukaryota	400682.PAC_15715252|-	O	zinc ion binding	-	-	2.3.2.27	ko:K12035	ko05206,map05206	-	-	-	ko00000,ko00001,ko01000,ko03019,ko04121	-	-	-	-
k59_36696_1	1046724.KB889908_gene989	9.56e-27	109.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,46506@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
k59_16559_1	756272.Plabr_3960	3.82e-74	245.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_70761_1	1165841.SULAR_09904	6.31e-100	300.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_50594_1	203275.BFO_1778	3.19e-05	47.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,2FMT6@200643|Bacteroidia,22Y4K@171551|Porphyromonadaceae	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_3220_1	97096.XP_007798908.1	6.27e-08	63.2	2CH50@1|root,2QVJA@2759|Eukaryota,38I5H@33154|Opisthokonta,3NUEA@4751|Fungi,3QRRK@4890|Ascomycota	4751|Fungi	S	deiminase	-	-	3.5.3.15	ko:K01481	-	-	-	-	ko00000,ko01000	-	-	-	PAD
k59_43843_1	522373.Smlt3218	1.44e-45	158.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1X44M@135614|Xanthomonadales	135614|Xanthomonadales	M	phospholipase	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_23694_1	1429851.X548_19465	3.38e-55	194.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_159321_1	1165841.SULAR_03267	1.57e-87	261.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2YMH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_57639_1	313596.RB2501_06545	5.41e-190	538.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_179370_1	2340.JV46_05710	2.39e-42	148.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1J4QV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	stress-induced protein	yicC	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_77968_1	472759.Nhal_2761	1.26e-50	176.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WWEY@135613|Chromatiales	135613|Chromatiales	C	FAD linked oxidase	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_193242_1	395493.BegalDRAFT_0207	8.1e-169	505.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T4BF@1236|Gammaproteobacteria	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	chiS	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg,Y_Y_Y
k59_30706_1	1268622.AVS7_01625	1.23e-10	67.8	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1-like protein	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_71152_1	864702.OsccyDRAFT_3461	9.85e-43	159.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_57642_1	981085.XP_010087824.1	2.45e-05	46.2	COG1643@1|root,KOG0920@2759|Eukaryota,37KD0@33090|Viridiplantae,3G8MK@35493|Streptophyta,4JD5Y@91835|fabids	35493|Streptophyta	A	ATP-dependent RNA helicase	-	GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0001012,GO:0001047,GO:0001067,GO:0001503,GO:0001817,GO:0001819,GO:0002151,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0003724,GO:0003725,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006725,GO:0006807,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009605,GO:0009607,GO:0009615,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010638,GO:0014070,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032204,GO:0032206,GO:0032479,GO:0032481,GO:0032501,GO:0032647,GO:0032727,GO:0032879,GO:0032880,GO:0033043,GO:0033044,GO:0034641,GO:0042221,GO:0042623,GO:0042826,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043330,GO:0043331,GO:0043487,GO:0043489,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051052,GO:0051054,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051707,GO:0051880,GO:0060255,GO:0065007,GO:0065008,GO:0070034,GO:0070035,GO:0070201,GO:0071704,GO:0080090,GO:0090087,GO:0090304,GO:0090669,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901698,GO:1902369,GO:1902680,GO:1902739,GO:1902741,GO:1903506,GO:1903508,GO:1903530,GO:1903532,GO:1904951,GO:1990837,GO:2000112,GO:2001141,GO:2001252	3.6.4.13	ko:K14442	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,HA2,Helicase_C,OB_NTP_bind,dsrm
k59_145883_1	68170.KL590487_gene8770	5.01e-05	48.9	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria,4E05A@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_213578_1	1249997.JHZW01000002_gene1713	1.53e-56	184.0	28HGK@1|root,2Z7SE@2|Bacteria,4NGDR@976|Bacteroidetes,1I856@117743|Flavobacteriia	976|Bacteroidetes	S	Malonate/sodium symporter MadM subunit	-	-	-	-	-	-	-	-	-	-	-	-	MadM
k59_105220_1	1165841.SULAR_02953	2.77e-124	370.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_172911_1	929558.SMGD1_1616	3.85e-40	147.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_172911_2	2340.JV46_05410	1.15e-20	90.9	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1J4ST@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0306 Phosphate sulphate permeases	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_132333_2	1121396.KB893001_gene3994	2.69e-16	79.3	COG3210@1|root,COG3210@2|Bacteria,1QA27@1224|Proteobacteria,42YV9@68525|delta/epsilon subdivisions,2WUC5@28221|Deltaproteobacteria,2MMYW@213118|Desulfobacterales	28221|Deltaproteobacteria	U	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
k59_119007_1	1165841.SULAR_04612	1.07e-94	293.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GGDEF,PAS_9,dCache_3
k59_91630_2	1165841.SULAR_00340	5.31e-72	226.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_77989_1	1165841.SULAR_04127	4.16e-107	314.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2YM9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_138903_1	2340.JV46_17130	1.3e-81	253.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1J4Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_186445_1	314275.MADE_1008400	1.94e-11	63.9	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,46442@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_186445_2	1535422.ND16A_3772	7.57e-97	289.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,1RPDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphoglucomutase	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_186447_1	1267534.KB906756_gene218	1.62e-36	138.0	COG0763@1|root,COG0763@2|Bacteria,3Y34H@57723|Acidobacteria,2JID9@204432|Acidobacteriia	204432|Acidobacteriia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_186447_2	653733.Selin_2283	1.49e-55	185.0	COG0499@1|root,COG0499@2|Bacteria	2|Bacteria	H	adenosylhomocysteinase activity	ahcY	GO:0000096,GO:0000097,GO:0000098,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0035375,GO:0035635,GO:0036094,GO:0036293,GO:0040007,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0070482,GO:0071268,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_105234_1	886293.Sinac_1231	6.39e-48	169.0	COG3464@1|root,COG3464@2|Bacteria,2J4EX@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159349_1	1443665.JACA01000033_gene1842	6.1e-30	119.0	COG1721@1|root,COG1721@2|Bacteria,4NFX4@976|Bacteroidetes,1HXMB@117743|Flavobacteriia,2YJ42@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_43882_1	293826.Amet_4631	2.05e-43	151.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,36DZX@31979|Clostridiaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	baiA	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
k59_3612_1	395495.Lcho_2430	1.28e-49	176.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,1KJG8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_186455_1	1267535.KB906767_gene4240	2.67e-41	154.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
k59_145915_1	536232.CLM_2409	1.97e-80	249.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,36E2Z@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_6095_2	694431.DESACE_00480	1.18e-12	69.7	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k59_148396_1	565045.NOR51B_1612	2.65e-42	144.0	COG2343@1|root,COG2343@2|Bacteria,1RJ3M@1224|Proteobacteria,1T0E0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
k59_148396_2	1219072.VHA01S_004_01420	3.37e-33	119.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,1XXKV@135623|Vibrionales	135623|Vibrionales	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_154888_2	1232437.KL662042_gene2011	3.18e-44	151.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,42Y9C@68525|delta/epsilon subdivisions,2WUJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_73380_1	382464.ABSI01000006_gene819	2.84e-50	172.0	COG3693@1|root,COG3693@2|Bacteria,46URW@74201|Verrucomicrobia,2IVBA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
k59_87154_1	1168289.AJKI01000015_gene2161	5.53e-41	151.0	COG1026@1|root,COG1026@2|Bacteria,4PJ9W@976|Bacteroidetes,2G279@200643|Bacteroidia,3XKNA@558415|Marinilabiliaceae	976|Bacteroidetes	S	Peptidase M16C associated	-	-	-	-	-	-	-	-	-	-	-	-	M16C_assoc,Peptidase_M16_C
k59_148399_1	13333.ERN02618	2.57e-96	315.0	COG0052@1|root,COG0356@1|root,KOG0832@2759|Eukaryota,KOG4665@2759|Eukaryota,38964@33090|Viridiplantae,3GY32@35493|Streptophyta	35493|Streptophyta	J	RNA polymerase Rpb1, domain 5	rpoC2	-	2.7.7.6	ko:K02108,ko:K03046	ko00190,ko00195,ko00230,ko00240,ko01100,ko03020,map00190,map00195,map00230,map00240,map01100,map03020	M00157,M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko00194,ko01000,ko03021,ko03110,ko03400	3.A.2.1	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,Ribosomal_S2
k59_39313_1	398512.JQKC01000023_gene3346	4.76e-99	301.0	COG0012@1|root,COG0012@2|Bacteria,1UIBA@1239|Firmicutes,24DM9@186801|Clostridia	186801|Clostridia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141250_1	313596.RB2501_03185	3.29e-104	324.0	COG3203@1|root,COG3203@2|Bacteria,4PKBJ@976|Bacteroidetes,1HYG6@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_154891_1	1049564.TevJSym_am00820	9.56e-134	394.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1J5BJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0022411,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032984,GO:0034641,GO:0034645,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_161799_1	1249627.D779_0053	1.1e-94	291.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales	135613|Chromatiales	U	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_161799_2	1042375.AFPL01000044_gene1290	1.96e-17	75.9	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,467D0@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_80351_1	1177179.A11A3_13720	1.58e-12	60.8	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria,1XM7A@135619|Oceanospirillales	135619|Oceanospirillales	C	rubredoxin	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_80351_2	1034943.BN1094_02659	9.8e-18	81.6	COG1376@1|root,COG1376@2|Bacteria,1RDA8@1224|Proteobacteria,1S4PD@1236|Gammaproteobacteria,1JCVH@118969|Legionellales	118969|Legionellales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_19558_1	1123368.AUIS01000029_gene1289	1.96e-89	282.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,2NBWK@225057|Acidithiobacillales	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_202381_1	1165841.SULAR_05348	1.25e-68	231.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2YM9E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL,Patched
k59_168558_2	531844.FIC_01598	1e-35	132.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWRC@117743|Flavobacteriia,405U1@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_181936_1	1123401.JHYQ01000025_gene3320	1.51e-25	106.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,460Z9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_175231_1	653733.Selin_2134	6.72e-43	155.0	COG2838@1|root,COG2838@2|Bacteria	2|Bacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_134764_1	1168034.FH5T_12555	4.88e-57	189.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,2FPG5@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_134764_2	376686.Fjoh_4970	3.38e-22	92.8	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,1I1SA@117743|Flavobacteriia,2NT92@237|Flavobacterium	976|Bacteroidetes	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_33055_1	1122179.KB890469_gene602	2.32e-66	226.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1IQA2@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_181944_1	2340.JV46_22570	1.54e-63	211.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,1RR35@1236|Gammaproteobacteria,1J87X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k59_148428_1	1165841.SULAR_00225	3.8e-95	281.0	COG0212@1|root,COG0212@2|Bacteria,1RDZJ@1224|Proteobacteria,42SXM@68525|delta/epsilon subdivisions,2YPJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_148428_2	1165841.SULAR_00230	2.26e-24	103.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_161813_1	2340.JV46_18870	1.57e-32	124.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1J57C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_60639_1	879212.DespoDRAFT_01215	1.75e-59	195.0	COG3335@1|root,COG3335@2|Bacteria,1R1IX@1224|Proteobacteria,43DBP@68525|delta/epsilon subdivisions,2X8HP@28221|Deltaproteobacteria,2MN2B@213118|Desulfobacterales	1224|Proteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_155338_1	1165841.SULAR_02743	1.33e-86	265.0	COG0479@1|root,COG0479@2|Bacteria,1QE4T@1224|Proteobacteria,42QE6@68525|delta/epsilon subdivisions,2YM7P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_47001_1	1247963.JPHU01000001_gene2087	2.98e-21	90.1	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Outer membrane protein W	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_188816_1	1168034.FH5T_06060	4.27e-114	339.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,2FMRM@200643|Bacteroidia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_155340_1	1307437.J139_09346	1.18e-67	217.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,2PZV3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG1194 A G-specific DNA glycosylase	mutY	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_87657_1	330214.NIDE2328	2.57e-53	180.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	lmbP	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_141692_1	1476391.X5KCB6_9CAUD	2.14e-43	163.0	4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae	10744|Podoviridae	S	DNA polymerase family A	-	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_135097_1	1121948.AUAC01000005_gene2012	5.19e-21	97.1	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,2TWZ1@28211|Alphaproteobacteria,44159@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Trans_reg_C
k59_60645_1	187272.Mlg_0353	6.63e-32	129.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X102@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_121587_1	595460.RRSWK_01373	3.53e-26	114.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
k59_67493_1	644107.SL1157_0471	2.62e-44	159.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,4NARN@97050|Ruegeria	28211|Alphaproteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
k59_80800_1	1165841.SULAR_05233	8.82e-142	404.0	COG2204@1|root,COG2204@2|Bacteria,1QASN@1224|Proteobacteria,42RV2@68525|delta/epsilon subdivisions,2YP76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activ_2,Sigma54_activat
k59_162114_2	1173022.Cri9333_2605	2.02e-37	129.0	COG1359@1|root,COG1359@2|Bacteria,1G8H0@1117|Cyanobacteria,1HC7H@1150|Oscillatoriales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_148747_1	1121381.JNIV01000209_gene3332	1.49e-34	124.0	COG1487@1|root,COG1487@2|Bacteria,1WKHG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
k59_148747_2	202956.BBNL01000003_gene1288	3.65e-17	74.7	COG4456@1|root,COG4456@2|Bacteria,1QSWZ@1224|Proteobacteria,1RWHY@1236|Gammaproteobacteria,3NPKM@468|Moraxellaceae	1236|Gammaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
k59_216173_1	91604.ID47_08260	4.31e-44	147.0	COG3293@1|root,32RFK@2|Bacteria,1RI8T@1224|Proteobacteria,2UXPF@28211|Alphaproteobacteria,47GMW@766|Rickettsiales	766|Rickettsiales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
k59_216173_2	1385420.FRA_34c05850	2.11e-46	155.0	COG1234@1|root,COG1234@2|Bacteria,1MZ04@1224|Proteobacteria,1SF4J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_4
k59_87672_1	1165841.SULAR_01450	1.2e-17	76.6	COG3630@1|root,COG3630@2|Bacteria	2|Bacteria	C	sodium ion export across plasma membrane	oadG	GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
k59_87672_2	1165841.SULAR_01445	6.55e-40	144.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DEAD DEAH box helicase	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_19927_1	443152.MDG893_04492	4.42e-49	164.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,464M8@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
k59_128201_1	714943.Mucpa_5251	4.71e-29	119.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1J0JM@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	todS_10	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_114241_1	1169143.KB911034_gene1484	2.49e-81	253.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1K39S@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	phbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_47026_2	2340.JV46_27860	4.07e-26	105.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1JBHG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	ArsB,CitMHS
k59_13036_1	941824.TCEL_00365	2.17e-60	205.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,36EHV@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_188828_1	765911.Thivi_3793	2.45e-08	57.8	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria,1WYSZ@135613|Chromatiales	135613|Chromatiales	D	PFAM Sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_39745_2	1122194.AUHU01000005_gene871	2.05e-48	162.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,466SY@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_47027_1	1123401.JHYQ01000025_gene3341	2.44e-52	180.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,45ZSH@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_47027_2	2340.JV46_13020	3.17e-28	110.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1J5A7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the thiolase family	yqeF	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034308,GO:0034309,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046165,GO:0046395,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:0072329,GO:1901575,GO:1901576,GO:1901615,GO:1901617	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSSON_1240.SSON_3004	Thiolase_C,Thiolase_N
k59_60665_1	1492737.FEM08_15000	2.05e-10	67.0	COG4886@1|root,COG4886@2|Bacteria,4NI2K@976|Bacteroidetes,1I0CI@117743|Flavobacteriia,2NTVA@237|Flavobacterium	976|Bacteroidetes	S	Pfam Leucine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_6,LRR_8
k59_26623_2	1131553.JIBI01000039_gene1942	1.25e-22	98.6	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,2VPGJ@28216|Betaproteobacteria,3728R@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA2	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_169104_1	247634.GPB2148_3603	1.25e-101	301.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,1J4QA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0714 MoxR-like ATPases	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_216183_1	756067.MicvaDRAFT_5243	1.98e-38	141.0	COG3950@1|root,COG3950@2|Bacteria,1G26S@1117|Cyanobacteria,1H9HD@1150|Oscillatoriales	1117|Cyanobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
k59_47030_1	465817.ETA_22510	1.39e-85	266.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,3X59R@551|Erwinia	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_188834_1	1266925.JHVX01000013_gene1665	4.4e-29	120.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,372H6@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_216184_1	565045.NOR51B_1971	1.43e-86	277.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,1RN0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	CTI
k59_169107_2	1147.D082_06070	1.59e-11	65.1	COG3001@1|root,COG3001@2|Bacteria,1G040@1117|Cyanobacteria,1H4IJ@1142|Synechocystis	1117|Cyanobacteria	G	Fructosamine kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_128210_1	384765.SIAM614_21355	1.68e-84	282.0	COG1112@1|root,COG2852@1|root,COG1112@2|Bacteria,COG2852@2|Bacteria,1MWMG@1224|Proteobacteria,2TSE1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1112 Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559,WGR
k59_165762_1	1454004.AW11_04033	1.99e-41	142.0	COG0310@1|root,COG0310@2|Bacteria,1MXW7@1224|Proteobacteria,2VP3N@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
k59_213328_1	999419.HMPREF1077_02732	1.78e-84	267.0	COG1070@1|root,COG1070@2|Bacteria,4NIJC@976|Bacteroidetes,2FP4C@200643|Bacteroidia,22X3Q@171551|Porphyromonadaceae	976|Bacteroidetes	G	FGGY family of carbohydrate kinases, N-terminal domain	rhaB	GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_118705_1	1054217.TALC_00629	1.59e-29	117.0	COG0002@1|root,arCOG00495@2157|Archaea,2XTC1@28890|Euryarchaeota,2425Z@183967|Thermoplasmata	183967|Thermoplasmata	E	Belongs to the NAGSA dehydrogenase family. Type 1 subfamily	-	-	1.2.1.38	ko:K00145,ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00028,M00031,M00763,M00845	R03443,R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_179098_1	445696.E3SST5_9CAUD	1.02e-26	118.0	4QIJU@10662|Myoviridae	10662|Myoviridae	S	virus tail assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159086_1	313596.RB2501_08585	3.58e-82	269.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_98295_1	387093.SUN_1850	9.09e-17	79.3	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_98295_2	1123279.ATUS01000002_gene297	5.88e-62	203.0	COG0531@1|root,COG0531@2|Bacteria,1QXK2@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	AA_permease_2
k59_36846_1	686340.Metal_1989	9.46e-57	187.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XE3A@135618|Methylococcales	135618|Methylococcales	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_138685_1	1122194.AUHU01000008_gene3282	1.42e-13	77.8	COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
k59_64175_1	1056820.KB900633_gene2031	1.09e-26	116.0	COG3299@1|root,COG3299@2|Bacteria,1R96N@1224|Proteobacteria,1SXWZ@1236|Gammaproteobacteria,2PQ5I@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_145622_1	861299.J421_1459	3.64e-18	79.7	2EAHU@1|root,334M0@2|Bacteria,1ZV5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_145622_2	204669.Acid345_4667	1.19e-40	137.0	COG0346@1|root,COG0346@2|Bacteria,3Y85T@57723|Acidobacteria,2JN5Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_3390_2	4641.GSMUA_AchrUn_randomP21780_001	1.25e-153	481.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,3KRI7@4447|Liliopsida	35493|Streptophyta	K	Dna-directed rna polymerase	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_138687_1	1117318.PRUB_21822	9.91e-33	130.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,2PZQP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303,ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iPC815.YPO0158	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_10015_1	189753.AXAS01000002_gene5201	1.61e-08	58.2	COG4206@1|root,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,2TU7B@28211|Alphaproteobacteria,3JVXG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_23509_1	96561.Dole_1930	7.74e-51	169.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_118726_2	438753.AZC_0427	8.94e-13	64.7	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria,3EZN6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_57358_1	1165841.SULAR_09559	2.46e-134	383.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42N4V@68525|delta/epsilon subdivisions,2YN04@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	rluA	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_165763_1	998674.ATTE01000001_gene3756	4.58e-31	120.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_64181_1	1165841.SULAR_09089	5.3e-106	316.0	COG0642@1|root,COG2205@2|Bacteria,1QZF7@1224|Proteobacteria,43CIH@68525|delta/epsilon subdivisions,2YTD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_138695_1	1110502.TMO_1165	3.22e-31	119.0	COG1695@1|root,COG1695@2|Bacteria,1N33P@1224|Proteobacteria,2VER5@28211|Alphaproteobacteria,2JYHP@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
k59_186204_1	1173027.Mic7113_1195	3.73e-45	167.0	COG0784@1|root,COG3437@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_200386_1	7668.SPU_025385-tr	7.86e-29	120.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_152892_1	565045.NOR51B_1278	2.74e-65	210.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_23966_1	1122137.AQXF01000004_gene1506	8.82e-45	170.0	COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2U11H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
k59_125729_1	396588.Tgr7_1157	3.72e-87	283.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales	135613|Chromatiales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_186671_1	2340.JV46_13530	6.61e-49	163.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C
k59_51133_1	498211.CJA_3132	9.38e-59	202.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1FH1F@10|Cellvibrio	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_166277_2	1242864.D187_002045	1.31e-45	166.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WUE6@28221|Deltaproteobacteria,2YTX9@29|Myxococcales	28221|Deltaproteobacteria	V	Efflux ABC transporter, permease ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_17248_1	1168034.FH5T_05955	3.08e-58	182.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,2FV5K@200643|Bacteroidia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
k59_17248_2	742767.HMPREF9456_00233	3.23e-24	99.4	COG0731@1|root,COG0731@2|Bacteria,4NJEM@976|Bacteroidetes,2FMWY@200643|Bacteroidia,22WAC@171551|Porphyromonadaceae	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
k59_152898_1	1394178.AWOO02000091_gene1048	1.7e-84	262.0	COG0161@1|root,COG0161@2|Bacteria,2I2DN@201174|Actinobacteria,4EGKX@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_91886_1	1121405.dsmv_3289	2.96e-159	461.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
k59_105517_2	370438.PTH_1622	2.35e-27	109.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,260FR@186807|Peptococcaceae	186801|Clostridia	E	PFAM DAHP synthetase I	aroF1	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_78288_2	72658.Bostr.12863s0004.1.p	2.04e-78	240.0	2CVK7@1|root,2RS7A@2759|Eukaryota,37RP9@33090|Viridiplantae,3GGMM@35493|Streptophyta	35493|Streptophyta	S	MttB protein	mttB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	-	-	-	-	-	-	-	-	-	TatC
k59_166284_1	273121.WS0069	2.65e-64	207.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2YM84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k59_98843_1	1121405.dsmv_2282	7.95e-54	189.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,42TBM@68525|delta/epsilon subdivisions,2WP92@28221|Deltaproteobacteria,2MPCA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
k59_44138_1	1122176.KB903539_gene1375	7.93e-18	77.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
k59_44138_2	948106.AWZT01000030_gene4802	6e-73	229.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,2VJZI@28216|Betaproteobacteria,1K0UP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_30966_1	1168034.FH5T_04170	3.05e-14	77.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_78293_1	742766.HMPREF9455_02391	2.51e-15	76.3	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia,22XC3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_78293_2	1168034.FH5T_01215	1.51e-73	221.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,2FSYB@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_193593_1	518766.Rmar_2423	1.76e-102	324.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes	976|Bacteroidetes	T	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_30970_2	717774.Marme_1269	4.32e-38	142.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XHJX@135619|Oceanospirillales	135619|Oceanospirillales	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k59_112010_1	187272.Mlg_1343	3.13e-49	172.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_125748_1	243365.CV_3695	4.67e-114	337.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,2KQFE@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_78298_1	1037409.BJ6T_56200	6.51e-71	230.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2TU9Q@28211|Alphaproteobacteria,3JW1M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_37342_1	449673.BACSTE_03217	1.37e-15	80.9	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMCC@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_213778_1	1165841.SULAR_05113	5.06e-50	167.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2YMPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_213778_2	1355374.JARU01000013_gene53	1.24e-30	113.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,42T0B@68525|delta/epsilon subdivisions,2YP5M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_10448_1	1165841.SULAR_09679	5.05e-145	429.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_71450_1	1165841.SULAR_00060	1.26e-104	325.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_78309_1	1165841.SULAR_01350	6.03e-98	310.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_71451_1	1227739.Hsw_2641	1.05e-19	92.4	COG0577@1|root,COG0577@2|Bacteria,4NI8K@976|Bacteroidetes,47KIT@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_44164_1	926559.JoomaDRAFT_0139	3.82e-71	225.0	COG3039@1|root,COG3039@2|Bacteria,4NGHT@976|Bacteroidetes,1HZR7@117743|Flavobacteriia	976|Bacteroidetes	L	Pfam Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_98850_1	1123400.KB904790_gene216	1.56e-27	113.0	COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1S4ZG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
k59_132690_1	1165841.SULAR_07635	3.87e-187	534.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_78314_1	42565.FP66_11430	1.83e-71	235.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XICM@135619|Oceanospirillales	135619|Oceanospirillales	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_173159_1	46234.ANA_C12690	1.19e-07	62.4	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1G051@1117|Cyanobacteria,1HMY4@1161|Nostocales	1117|Cyanobacteria	LV	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
k59_105556_1	1122169.AREN01000003_gene1193	6.82e-07	49.7	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1JEB7@118969|Legionellales	118969|Legionellales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k59_105556_2	2340.JV46_20780	8.41e-66	207.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
k59_51172_1	1249627.D779_2141	5.58e-19	79.0	2E3CD@1|root,32YBP@2|Bacteria,1N8PD@1224|Proteobacteria,1SCSK@1236|Gammaproteobacteria,1WZ7C@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44173_1	880073.Calab_0798	2.33e-29	108.0	COG2131@1|root,COG2131@2|Bacteria,2NPW9@2323|unclassified Bacteria	2|Bacteria	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_44173_2	264462.Bd2408	1.62e-36	130.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1N34Y@1224|Proteobacteria,42TV3@68525|delta/epsilon subdivisions,2WQ5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
k59_91933_1	313603.FB2170_04060	3.12e-31	125.0	COG4772@1|root,COG4772@2|Bacteria,4PKRQ@976|Bacteroidetes,1HX89@117743|Flavobacteriia,2PGD1@252356|Maribacter	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_57951_1	1449357.JQLK01000001_gene1953	3.34e-08	53.9	COG4636@1|root,COG4636@2|Bacteria,1WM25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
k59_78319_2	1168034.FH5T_12840	2.07e-68	208.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,2FS3J@200643|Bacteroidia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_134908_2	1026970.XP_008823244.1	4.16e-09	65.1	KOG2401@1|root,KOG2401@2759|Eukaryota,39R9J@33154|Opisthokonta,3CNQA@33208|Metazoa,3E4W6@33213|Bilateria,48R2T@7711|Chordata,49MNV@7742|Vertebrata,3JPYT@40674|Mammalia	33208|Metazoa	L	AAA domain	N4BP2L2	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k59_53434_1	1183438.GKIL_2770	1.65e-85	283.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1G1EB@1117|Cyanobacteria	1117|Cyanobacteria	KLT	serine threonine protein kinase	-	-	2.7.1.37,2.7.11.1	ko:K00870,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase,TPR_11,TPR_16,TPR_8
k59_202600_1	1168034.FH5T_12120	7.28e-94	276.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,2FNRJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
k59_39520_1	1165841.SULAR_07555	6.09e-21	91.3	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_39520_2	1165841.SULAR_07550	3.06e-88	273.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_60407_1	1168034.FH5T_17865	2.31e-12	67.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,2FW3E@200643|Bacteroidia	976|Bacteroidetes	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_108036_1	1165841.SULAR_05483	2.31e-114	344.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_161950_1	716544.wcw_1073	1.33e-48	175.0	COG3264@1|root,COG3264@2|Bacteria,2JFV5@204428|Chlamydiae	204428|Chlamydiae	M	Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_94302_1	118168.MC7420_860	5.93e-60	202.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Trypsin_2
k59_12747_1	426117.M446_0169	8.88e-24	99.0	COG3208@1|root,COG3208@2|Bacteria,1RGYT@1224|Proteobacteria,2U9ZM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase domain	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Thioesterase
k59_175962_1	1165841.SULAR_09409	5.41e-107	316.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2YMM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_13223_1	313596.RB2501_02685	1.15e-100	304.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,1HWX3@117743|Flavobacteriia	976|Bacteroidetes	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_53814_1	1279017.AQYJ01000016_gene434	4.83e-142	408.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,465IU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS116/IS110/IS902 family	Z012_08285	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_196209_2	82996.sch_00615	2.74e-39	148.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria,400NV@613|Serratia	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_155487_1	1124983.PFLCHA0_c06830	1.66e-39	137.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1YPGV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0560	DHquinase_II
k59_33599_1	317025.Tcr_1536	8.18e-73	220.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,460J9@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_87812_1	268746.Q58MM6_BPPRM	5.98e-41	151.0	4QHDM@10239|Viruses,4QYV6@35237|dsDNA viruses  no RNA stage,4QRD0@28883|Caudovirales,4QI2W@10662|Myoviridae	10662|Myoviridae	S	Terminase-like family	-	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949	-	-	-	-	-	-	-	-	-	-	-
k59_175963_1	314278.NB231_15163	2.05e-60	206.0	28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,1WW4J@135613|Chromatiales	135613|Chromatiales	S	Carboxysome shell peptide mid-region	-	-	-	-	-	-	-	-	-	-	-	-	CsoS2_M
k59_73797_1	196367.JNFG01000020_gene4594	1.58e-42	155.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,2VK41@28216|Betaproteobacteria,1K1NJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
k59_175964_1	765912.Thimo_0119	4.94e-78	252.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales	135613|Chromatiales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_121848_1	313596.RB2501_11137	2.41e-43	142.0	COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes,1I2YN@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_121848_2	313603.FB2170_01192	2.05e-44	154.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1HYDV@117743|Flavobacteriia,2PH0Y@252356|Maribacter	976|Bacteroidetes	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_87815_1	880073.Calab_0100	1.36e-23	100.0	COG0123@1|root,COG0123@2|Bacteria,2NRDM@2323|unclassified Bacteria	2|Bacteria	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_87815_2	930166.CD58_15405	4.46e-19	89.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_141870_2	1121403.AUCV01000003_gene1785	4.4e-16	76.6	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria	1224|Proteobacteria	D	involved in chromosome partitioning	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_189031_1	1049564.TevJSym_bk00230	2.03e-97	303.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Alpha amylase catalytic	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_73811_1	768671.ThimaDRAFT_0313	6.25e-19	84.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1WW2T@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
k59_73811_2	385682.AFSL01000006_gene2333	1.06e-34	122.0	COG0432@1|root,COG0432@2|Bacteria,4NUS2@976|Bacteroidetes,2FW13@200643|Bacteroidia,3XK30@558415|Marinilabiliaceae	976|Bacteroidetes	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_87827_1	1123393.KB891317_gene2372	7.2e-32	114.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,2W1W6@28216|Betaproteobacteria,1KSRH@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
k59_108436_1	1535422.ND16A_1956	4.63e-40	144.0	COG2270@1|root,COG2270@2|Bacteria,1QUVA@1224|Proteobacteria,1T226@1236|Gammaproteobacteria,2Q6F8@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Acetyl-coenzyme A transporter 1	Z012_03780	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_108436_2	94624.Bpet0422	5.44e-29	110.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,3T375@506|Alcaligenaceae	28216|Betaproteobacteria	L	Exodeoxyribonuclease III	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_101298_1	86106.I862_05015	1.23e-09	64.3	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2TWNB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
k59_128378_1	2340.JV46_27580	2.33e-107	335.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	ttrA	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K08357,ko:K21307	ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020	-	R10149,R10150,R11487	RC00168,RC02823,RC03109	ko00000,ko00001,ko01000,ko02000	5.A.3.10,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_189041_1	1168034.FH5T_12530	7.85e-99	301.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNG7@200643|Bacteroidia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_141890_1	1168034.FH5T_05050	3.21e-76	240.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,2FM6X@200643|Bacteroidia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_33615_1	509635.N824_24920	4.84e-09	63.5	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,1IPHA@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_94688_1	870187.Thini_3627	1.12e-101	317.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,45ZNI@72273|Thiotrichales	72273|Thiotrichales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_87841_1	857087.Metme_1706	9.86e-63	197.0	COG0454@1|root,COG0456@2|Bacteria,1N009@1224|Proteobacteria,1T54A@1236|Gammaproteobacteria,1XH1R@135618|Methylococcales	135618|Methylococcales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_87841_2	857087.Metme_1705	4.93e-35	122.0	COG4453@1|root,COG4453@2|Bacteria,1PW10@1224|Proteobacteria,1TEV8@1236|Gammaproteobacteria,1XGWH@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
k59_148963_2	1112214.AHIS01000091_gene952	2.57e-13	71.6	COG4916@1|root,COG4916@2|Bacteria,1R81D@1224|Proteobacteria,2U2YD@28211|Alphaproteobacteria,2K1CH@204457|Sphingomonadales	204457|Sphingomonadales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
k59_203042_1	983545.Glaag_1372	5.54e-100	308.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,464MC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_67700_1	2340.JV46_10370	9.8e-216	605.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1J5MK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0498 Threonine synthase	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
k59_216418_1	1165841.SULAR_03502	5e-86	259.0	COG0526@1|root,COG0526@2|Bacteria,1R0XY@1224|Proteobacteria,43D37@68525|delta/epsilon subdivisions,2YTFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_73841_1	78245.Xaut_1009	1.24e-42	160.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,3F0EP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,Nitroreductase,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_94694_1	1472716.KBK24_0105585	2.33e-24	95.9	COG3791@1|root,COG3791@2|Bacteria,1N263@1224|Proteobacteria,2VVWM@28216|Betaproteobacteria,1K7X3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating GFA	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_13277_1	329726.AM1_4438	6.02e-40	141.0	COG3335@1|root,COG3335@2|Bacteria,1G6I9@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
k59_182565_1	452637.Oter_3898	9.45e-07	55.8	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia,3K9Y4@414999|Opitutae	414999|Opitutae	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
k59_94695_1	1165841.SULAR_01928	1.13e-113	337.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2YNRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG2230 Cyclopropane fatty acid synthase and related	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_135330_1	1283300.ATXB01000001_gene1199	1.26e-10	61.2	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hydrolase	yigB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
k59_135330_2	1191299.AJYX01000099_gene835	6.69e-17	79.3	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1XSNT@135623|Vibrionales	135623|Vibrionales	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_182568_1	261292.Nit79A3_3309	5.68e-59	195.0	COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,2WFID@28216|Betaproteobacteria,372P9@32003|Nitrosomonadales	28216|Betaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_53861_1	1120966.AUBU01000013_gene433	2.03e-26	106.0	28N4A@1|root,2ZB9T@2|Bacteria,4NS50@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_203066_1	1535422.ND16A_1227	4.29e-18	88.6	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1T8KC@1236|Gammaproteobacteria,2Q8A4@267889|Colwelliaceae	1236|Gammaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_216432_2	1121022.ABENE_11320	2.28e-54	191.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	ko:K02014,ko:K15721	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.7.2	-	-	Plug,TonB_dep_Rec
k59_47318_1	102107.XP_008236536.1	2.1e-121	353.0	COG0356@1|root,KOG4665@2759|Eukaryota,37J5M@33090|Viridiplantae,3GEF0@35493|Streptophyta,4JSKT@91835|fabids	35493|Streptophyta	C	ATP synthase A chain	atp6-1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	-	ko:K02126	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko03029	3.A.2.1	-	-	ATP-synt_A
k59_209818_2	1121931.AUHG01000017_gene1618	1.24e-32	122.0	COG3279@1|root,COG3279@2|Bacteria,4NFZT@976|Bacteroidetes,1HYGC@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_135342_1	1168034.FH5T_08840	2.04e-20	88.6	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,2FNHF@200643|Bacteroidia	976|Bacteroidetes	M	Mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_135342_2	1168034.FH5T_08835	5.52e-08	52.8	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,2FNVR@200643|Bacteroidia	976|Bacteroidetes	Q	Psort location CytoplasmicMembrane, score 10.00	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_114351_1	999141.GME_05300	6.21e-50	173.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1XNBZ@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_94709_1	1238190.AMQY01000021_gene1593	3.13e-36	140.0	COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ORF located using Glimmer RBSfinder	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A,DNA_pol_A_exo1
k59_33640_1	745411.B3C1_09523	3.72e-30	123.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1J8HK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_67734_1	1515746.HR45_01105	4.08e-11	65.1	COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,2QDUF@267890|Shewanellaceae	1236|Gammaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	yigM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
k59_70809_1	1120953.AUBH01000004_gene3032	2.03e-97	298.0	COG1253@1|root,COG1253@2|Bacteria,1N0IQ@1224|Proteobacteria,1RY1D@1236|Gammaproteobacteria,46A5K@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	DUF21
k59_9897_2	1120746.CCNL01000009_gene872	2.58e-36	140.0	COG5002@1|root,COG5002@2|Bacteria,2NS51@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	baeS	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_70810_2	2340.JV46_28190	1.09e-59	187.0	2AAM4@1|root,30ZYM@2|Bacteria,1RFTG@1224|Proteobacteria,1S4UQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
k59_77651_1	1165841.SULAR_09369	3.12e-63	199.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	ydiY	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF3078,DUF481
k59_77651_2	1165841.SULAR_09364	4.01e-13	68.2	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_213214_1	1214242.B446_01685	1.44e-19	94.4	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K13611,ko:K13614	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_213603_1	1163617.SCD_n01730	6.39e-103	319.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJI0@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA_2
k59_64481_1	1397528.Q671_14960	1.23e-115	343.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales	135619|Oceanospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_166051_1	525897.Dbac_1386	6.5e-37	133.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2M9J5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
k59_166051_2	357808.RoseRS_0103	2.84e-19	81.6	COG4281@1|root,COG4281@2|Bacteria,2G98T@200795|Chloroflexi,377KT@32061|Chloroflexia	32061|Chloroflexia	I	PFAM acyl-coA-binding protein, ACBP	-	-	-	-	-	-	-	-	-	-	-	-	ACBP
k59_166051_3	105559.Nwat_0709	9.19e-48	157.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1WWRN@135613|Chromatiales	135613|Chromatiales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_57697_1	401053.AciPR4_0111	9.53e-12	68.9	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,3Y35S@57723|Acidobacteria,2JP33@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,Reg_prop,Y_Y_Y
k59_57697_2	1123057.P872_19995	9e-18	85.1	COG1960@1|root,COG1960@2|Bacteria,4NF87@976|Bacteroidetes,47NXN@768503|Cytophagia	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.3.6	ko:K00232	ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146	M00087,M00113	R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_200246_1	472759.Nhal_0357	5.39e-90	274.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXUS@135613|Chromatiales	1236|Gammaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_64485_1	1279015.KB908457_gene2208	9.09e-22	100.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1Y3XM@135624|Aeromonadales	135624|Aeromonadales	M	Soluble lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k59_159394_1	35754.JNYJ01000018_gene9576	1.18e-10	66.6	COG4221@1|root,COG4335@1|root,COG4221@2|Bacteria,COG4335@2|Bacteria,2GP05@201174|Actinobacteria,4DDJD@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_125521_1	1408433.JHXV01000010_gene585	4.8e-47	159.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia,2PAH9@246874|Cryomorphaceae	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_111869_1	1137799.GZ78_12510	2.93e-83	271.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1XHAB@135619|Oceanospirillales	135619|Oceanospirillales	K	accessory protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_85026_1	247634.GPB2148_197	5.96e-86	264.0	COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,1J59Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_179458_1	1121875.KB907549_gene1707	2.38e-14	77.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
k59_132407_1	598659.NAMH_0580	5.79e-48	172.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_132407_2	1165841.SULAR_02923	4.11e-83	262.0	COG0068@1|root,COG0068@2|Bacteria,1NS2D@1224|Proteobacteria,42RUP@68525|delta/epsilon subdivisions,2YP7H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hydE	-	-	-	-	-	-	-	-	-	-	-	-
k59_30771_1	1279017.AQYJ01000028_gene2405	3.99e-88	281.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_172978_1	387093.SUN_1139	3.25e-44	159.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2YNBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_172978_2	1165841.SULAR_04237	2.13e-24	97.4	COG0847@1|root,COG0847@2|Bacteria,1PDD1@1224|Proteobacteria,42MUX@68525|delta/epsilon subdivisions,2YNB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_85032_1	697282.Mettu_2626	7e-47	167.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XDUC@135618|Methylococcales	135618|Methylococcales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_166069_2	1120977.JHUX01000003_gene1875	8.82e-14	67.8	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,3NNGV@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
k59_64496_1	1165841.SULAR_07820	7.33e-37	128.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,42SKN@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_64496_2	472759.Nhal_3837	2.36e-33	120.0	COG0811@1|root,COG0811@2|Bacteria,1NZ0Y@1224|Proteobacteria,1SQUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_3683_1	929558.SMGD1_2123	3.96e-69	218.0	COG0598@1|root,COG0598@2|Bacteria,1NWUN@1224|Proteobacteria,42S8K@68525|delta/epsilon subdivisions,2YPDR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	CorA-like Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_125533_1	1165841.SULAR_09119	4.43e-118	355.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_132413_1	1168034.FH5T_12605	5.69e-85	271.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia	976|Bacteroidetes	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_23773_1	1165841.SULAR_06033	5.55e-160	451.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_207028_1	391625.PPSIR1_36839	1.22e-16	85.5	COG2960@1|root,COG2960@2|Bacteria,1Q61Y@1224|Proteobacteria,43B4H@68525|delta/epsilon subdivisions,2X6I7@28221|Deltaproteobacteria,2YUYN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
k59_172986_1	177437.HRM2_32920	4.18e-36	123.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_37158_1	935863.AWZR01000001_gene1871	2.07e-29	112.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1X60B@135614|Xanthomonadales	135614|Xanthomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_37158_2	283699.D172_2648	4.92e-06	49.3	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,2Q26T@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045261,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902600	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	OSCP
k59_166083_1	1168034.FH5T_08535	1.2e-130	392.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,2FME6@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_3695_1	768671.ThimaDRAFT_0335	1.62e-94	297.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_57730_1	1111730.ATTM01000002_gene1224	3.56e-07	52.8	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia,2NSQB@237|Flavobacterium	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_57730_2	865938.Weevi_1524	2.08e-20	91.3	COG0726@1|root,COG0726@2|Bacteria,4NRNQ@976|Bacteroidetes,1I4S0@117743|Flavobacteriia	976|Bacteroidetes	G	Xylanase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_179483_1	555779.Dthio_PD2228	3.85e-18	90.5	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2M85G@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_119080_1	349521.HCH_02591	5.32e-54	186.0	2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,1XN39@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_23790_1	472759.Nhal_3799	1.05e-51	169.0	COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_23790_2	555778.Hneap_0689	1.62e-30	112.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1WZ06@135613|Chromatiales	135613|Chromatiales	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
k59_125558_1	935548.KI912159_gene2822	1.02e-14	82.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,2UEFA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
k59_3706_1	314285.KT71_03157	6.68e-93	289.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1JBW7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_57738_1	1167006.UWK_03236	5.81e-05	44.3	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_57738_2	1121403.AUCV01000124_gene2974	2.58e-26	108.0	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2MMJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_119086_1	880073.Calab_1614	1.45e-62	212.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_139018_1	1165841.SULAR_06073	4.01e-91	278.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2YNE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_213633_1	396588.Tgr7_0992	3.36e-76	249.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_139023_1	1123236.KB899378_gene1672	2.98e-43	158.0	COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,46595@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
k59_173002_1	1232437.KL661989_gene449	2.01e-50	168.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WJYH@28221|Deltaproteobacteria,2MI0A@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_173002_2	1322246.BN4_20372	1.13e-17	83.2	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M11@68525|delta/epsilon subdivisions,2WK66@28221|Deltaproteobacteria,2M7WR@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_57748_1	1493511.A0A0E3FLK1_9CAUD	8.79e-68	221.0	4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae	10662|Myoviridae	S	DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98651_1	2340.JV46_27120	4.69e-41	150.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1J4HD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_98651_2	535289.Dtpsy_2572	2.83e-30	116.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,4AB6A@80864|Comamonadaceae	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_119097_1	7668.SPU_003319-tr	1.58e-112	369.0	2CMP4@1|root,2QR56@2759|Eukaryota,39VQX@33154|Opisthokonta,3BR69@33208|Metazoa,3E64E@33213|Bilateria	33208|Metazoa	S	Pao retrotransposon peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1759,Peptidase_A17,rve
k59_64530_1	765910.MARPU_13715	2.14e-20	84.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,1WYK5@135613|Chromatiales	135613|Chromatiales	S	PFAM Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_64530_2	2340.JV46_24710	4.35e-48	159.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S4ZT@1236|Gammaproteobacteria,1JBSY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ,TAT_signal
k59_200289_1	1123508.JH636446_gene6315	0.000161	49.3	COG0515@1|root,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8,WD40
k59_132462_1	1454004.AW11_00535	2.82e-71	234.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,2VKTF@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_85075_1	1165841.SULAR_00075	6.47e-156	451.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_37184_1	702450.CUW_1434	8.29e-26	111.0	COG4467@1|root,COG4467@2|Bacteria,1VK8R@1239|Firmicutes,3VTNX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_111883_1	72664.XP_006392428.1	4.97e-269	805.0	28Q0M@1|root,2QWP8@2759|Eukaryota,37SGC@33090|Viridiplantae,3G8GC@35493|Streptophyta	35493|Streptophyta	S	Zinc knuckle family protein	-	-	-	-	-	-	-	-	-	-	-	-	MP,RVP,zf-CCHC
k59_166127_1	2340.JV46_28850	9.9e-88	266.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,1J63G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_91715_1	1165841.SULAR_03213	1.47e-123	360.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2YMHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	rod shape-determining protein mreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_119103_1	550540.Fbal_3619	1.62e-37	138.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
k59_114783_2	113355.CM001775_gene689	2.19e-16	73.6	2EI5Q@1|root,33BX3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40447_1	1538644.KO02_01420	3.59e-65	208.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	4.1.1.46	ko:K07045,ko:K14333	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821	RC00390	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2,DDE_Tnp_1_4
k59_128661_1	717231.Flexsi_0338	1.21e-91	283.0	COG0034@1|root,COG0034@2|Bacteria,2GEKF@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_114799_1	95619.PM1_0226160	2.2e-16	77.4	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z0994	BATS,Radical_SAM
k59_114799_2	748658.KB907312_gene1488	1.83e-29	111.0	2E1SU@1|root,32X2N@2|Bacteria,1N4HW@1224|Proteobacteria,1SAEX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74182_1	1278073.MYSTI_02692	3.29e-64	225.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_182833_1	981085.XP_010100012.1	9.19e-163	457.0	COG0356@1|root,KOG4665@2759|Eukaryota,37MBD@33090|Viridiplantae,3GH9B@35493|Streptophyta,4JDXB@91835|fabids	35493|Streptophyta	C	it plays a direct role in the translocation of protons across the membrane	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009579,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098807,GO:0099131,GO:0099132,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_182833_3	218851.Aquca_038_00147.1	1.59e-43	142.0	COG0636@1|root,KOG0232@2759|Eukaryota,37W5A@33090|Viridiplantae,3GK4X@35493|Streptophyta	35493|Streptophyta	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_182833_4	3880.AES88228	3.47e-23	97.8	COG0052@1|root,COG0356@1|root,COG0636@1|root,KOG0232@2759|Eukaryota,KOG0832@2759|Eukaryota,KOG4665@2759|Eukaryota,37S1B@33090|Viridiplantae,3GHIA@35493|Streptophyta	35493|Streptophyta	J	ribosomal protein S2	rps2	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_182833_5	981085.XP_010100011.1	4.5e-69	214.0	COG0636@1|root,KOG0232@2759|Eukaryota	2759|Eukaryota	C	ATP hydrolysis coupled proton transport	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031976,GO:0031984,GO:0032991,GO:0033177,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02155,ko:K02919	ko00190,ko00195,ko01100,ko03010,ko04142,ko04145,ko04721,ko04966,ko05110,ko05120,ko05152,ko05323,map00190,map00195,map01100,map03010,map04142,map04145,map04721,map04966,map05110,map05120,map05152,map05323	M00157,M00160,M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00194,ko03011	3.A.2.1,3.A.2.2	-	-	ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_182833_6	4572.TRIUR3_00082-P1	0.0	885.0	COG0056@1|root,KOG1353@2759|Eukaryota,37JWW@33090|Viridiplantae,3G9FP@35493|Streptophyta	35493|Streptophyta	C	ATP synthase subunit alpha	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_182833_7	3880.AES87803	1.83e-15	71.2	2E3TA@1|root,2SAFC@2759|Eukaryota,37XB0@33090|Viridiplantae,3GKW4@35493|Streptophyta,4JVZD@91835|fabids	35493|Streptophyta	S	PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02710,ko:K02712	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbK
k59_182833_8	4155.Migut.G00430.1.p	2.59e-29	105.0	2E3TA@1|root,2SAFC@2759|Eukaryota,37XB0@33090|Viridiplantae,3GKW4@35493|Streptophyta	35493|Streptophyta	S	Photosystem II reaction center protein K	psbK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02710,ko:K02712	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbK
k59_182833_11	4155.Migut.H01168.1.p	4.89e-25	94.7	COG0228@1|root,KOG3419@2759|Eukaryota,37XEF@33090|Viridiplantae,3GM4M@35493|Streptophyta	35493|Streptophyta	J	Ribosomal protein S16	-	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_128670_1	234267.Acid_4623	1.19e-06	58.2	COG4447@1|root,COG4447@2|Bacteria,3Y2SN@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_189646_1	1265505.ATUG01000002_gene1740	1.02e-27	110.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	sarcosine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_189646_2	1121451.DESAM_22845	6.74e-85	256.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,42MVA@68525|delta/epsilon subdivisions,2WKBW@28221|Deltaproteobacteria,2M89C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_114823_1	768671.ThimaDRAFT_3771	8.97e-56	186.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1WW4C@135613|Chromatiales	135613|Chromatiales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_189649_1	1165841.SULAR_00010	3.46e-79	238.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2YPWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_128673_2	313612.L8106_01902	1.36e-13	71.6	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_74214_2	1177154.Y5S_03492	0.000242	45.4	COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,1XMRE@135619|Oceanospirillales	135619|Oceanospirillales	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_6,TPR_8
k59_189692_1	768671.ThimaDRAFT_0847	2.75e-40	150.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1SA31@1236|Gammaproteobacteria	1224|Proteobacteria	T	SMART ATP-binding region, ATPase-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3
k59_114872_1	395493.BegalDRAFT_3236	1.06e-17	82.4	COG2304@1|root,COG2304@2|Bacteria,1QVQA@1224|Proteobacteria,1S9W8@1236|Gammaproteobacteria,461GN@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4381)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4381
k59_114872_2	395493.BegalDRAFT_0037	1.69e-29	115.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,4604T@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
k59_189695_2	3694.POPTR_1512s00200.1	1.57e-18	90.1	KOG1075@1|root,KOG1075@2759|Eukaryota,37TIF@33090|Viridiplantae,3G9IZ@35493|Streptophyta,4JJZN@91835|fabids	35493|Streptophyta	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,RVT_1,RVT_3,zf-RVT
k59_182865_1	10228.TriadP33902	1.64e-07	47.8	2DZEY@1|root,2S6ZB@2759|Eukaryota,3A8VS@33154|Opisthokonta,3BUFV@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182865_2	3847.GLYMA13G11980.1	3.54e-81	271.0	2CUMQ@1|root,2RN4M@2759|Eukaryota,37U2D@33090|Viridiplantae,3GX5D@35493|Streptophyta,4JTXP@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182865_3	981085.XP_010106598.1	4.22e-29	110.0	2E13Y@1|root,2S8GD@2759|Eukaryota,38843@33090|Viridiplantae,3GW79@35493|Streptophyta,4JVE3@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128699_1	1123008.KB905695_gene2485	2.95e-23	97.8	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia,22X50@171551|Porphyromonadaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_128699_2	1168034.FH5T_08435	9.13e-52	177.0	28KJP@1|root,2ZA4Q@2|Bacteria,4NKJJ@976|Bacteroidetes,2FR8N@200643|Bacteroidia	976|Bacteroidetes	S	Putative binding domain, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BACON
k59_189698_1	243090.RB10558	6.81e-73	235.0	COG4935@1|root,COG5126@1|root,COG4935@2|Bacteria,COG5126@2|Bacteria,2J0WB@203682|Planctomycetes	203682|Planctomycetes	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,P_proprotein
k59_189701_1	675813.VIB_001568	2.34e-84	266.0	COG1479@1|root,COG1479@2|Bacteria,1NRBC@1224|Proteobacteria,1RY6F@1236|Gammaproteobacteria,1XY9K@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
k59_189709_1	313628.LNTAR_09801	3.42e-42	154.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.12	ko:K01135,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
k59_189711_1	582345.D6RRL6_BPKPP	2.09e-44	156.0	4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses  no RNA stage,4QQ2S@28883|Caudovirales	28883|Caudovirales	S	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114897_1	387093.SUN_1625	4.14e-82	256.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
k59_114900_1	384765.SIAM614_02581	9.15e-66	216.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_40567_1	1165841.SULAR_07735	3.08e-103	315.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2YNP4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_40593_1	1165841.SULAR_03322	1.43e-75	233.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2YMK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
k59_114945_1	1165841.SULAR_03567	1.11e-98	310.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Belongs to the peptidase S16 family	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_182919_1	1392486.JIAF01000004_gene1399	2.62e-68	228.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,2FMSF@200643|Bacteroidia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_74288_1	1095769.CAHF01000022_gene432	4.62e-53	191.0	COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
k59_40652_1	639030.JHVA01000001_gene1114	1.26e-33	125.0	2DKZK@1|root,310GY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
k59_182938_1	1297865.APJD01000001_gene5965	1.94e-09	63.2	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2TS08@28211|Alphaproteobacteria,3JUB7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128753_1	1123325.JHUV01000009_gene461	4.7e-99	305.0	COG0439@1|root,COG0439@2|Bacteria,2G3K4@200783|Aquificae	200783|Aquificae	I	PFAM Carbamoyl-phosphate synthase L chain	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_128753_2	749222.Nitsa_0802	2.86e-07	50.8	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2YM8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_182962_1	1165841.SULAR_03587	1.13e-68	230.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_74334_1	1168034.FH5T_06155	1.41e-92	286.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,2FNMT@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_74347_1	435908.IDSA_04710	1.3e-15	75.9	COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,1S8VN@1236|Gammaproteobacteria,2QG7N@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Uncharacterized conserved protein (DUF2358)	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_128778_1	1165841.SULAR_03043	1.88e-186	524.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	PFAM SufBD protein	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
k59_128778_2	1165841.SULAR_03038	9.36e-28	106.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,42PD0@68525|delta/epsilon subdivisions,2YNP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_182986_2	595537.Varpa_2084	2.72e-56	186.0	COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,2VP6N@28216|Betaproteobacteria,4ACSU@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix type 11 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
k59_74367_1	391625.PPSIR1_00812	1.54e-140	413.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_115104_1	10665.EXO1_BPT4	4.53e-40	145.0	4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses  no RNA stage,4QPEB@28883|Caudovirales,4QHXI@10662|Myoviridae	10662|Myoviridae	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115113_1	1168034.FH5T_01880	8.02e-25	103.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,2FQ8Y@200643|Bacteroidia	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_115113_2	1168034.FH5T_01875	1.52e-69	213.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,2FTAK@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG14473 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115132_1	1049564.TevJSym_bb00230	4.72e-79	263.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_74405_1	713586.KB900536_gene2975	3.83e-16	81.6	2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,1WXMV@135613|Chromatiales	135613|Chromatiales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
k59_74433_1	909663.KI867150_gene1067	7.96e-36	124.0	COG0847@1|root,COG0847@2|Bacteria,1N05B@1224|Proteobacteria,42UFX@68525|delta/epsilon subdivisions,2WQS3@28221|Deltaproteobacteria,2MQI7@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	CRISPR-associated protein (Cas_Cas2CT1978)	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978
k59_74433_2	1121456.ATVA01000001_gene3057	0.000886	40.8	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,42MT5@68525|delta/epsilon subdivisions,2WJNG@28221|Deltaproteobacteria,2M9PN@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k59_115191_1	585394.RHOM_02595	5.6e-09	62.8	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
k59_115196_1	1123256.KB907936_gene2563	1.55e-05	53.1	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,1T2MP@1236|Gammaproteobacteria,1XCQD@135614|Xanthomonadales	135614|Xanthomonadales	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_74452_1	1046724.KB889828_gene2913	3.52e-90	275.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,464H0@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_74464_1	869213.JCM21142_93819	1.13e-07	53.9	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_74464_2	1218103.CIN01S_20_00400	8.97e-06	47.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1HX1R@117743|Flavobacteriia,3ZPMS@59732|Chryseobacterium	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_74465_1	1168034.FH5T_09550	3.09e-65	205.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,2FMX2@200643|Bacteroidia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_74532_1	715451.ambt_15665	1.75e-42	153.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_74545_1	28229.ND2E_1953	1.22e-19	90.1	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,2Q614@267889|Colwelliaceae	1236|Gammaproteobacteria	J	Formyl transferase, C-terminal domain	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
k59_501_2	1348908.KI518584_gene1653	7.19e-63	194.0	COG4898@1|root,COG4898@2|Bacteria,1V6U6@1239|Firmicutes,4HH1D@91061|Bacilli,1ZG6X@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
k59_136004_1	326297.Sama_1004	1.49e-109	328.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,2Q9R5@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_156456_2	1165841.SULAR_01683	4.06e-100	291.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2YNVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1038	DHquinase_II
k59_156456_3	1165841.SULAR_01688	8.83e-109	322.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_108917_1	1121127.JAFA01000031_gene4654	1.89e-17	82.4	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2VJ40@28216|Betaproteobacteria,1K4VW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_122505_1	349965.yinte0001_25520	6.57e-63	205.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,41ERC@629|Yersinia	1236|Gammaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_14089_1	506534.Rhein_2980	6.97e-15	76.3	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1WW5G@135613|Chromatiales	135613|Chromatiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_144699_1	377629.TERTU_4027	1.98e-09	55.5	2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria,2PQJD@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
k59_36266_1	1500893.JQNB01000001_gene714	2.4e-49	173.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1X4KT@135614|Xanthomonadales	135614|Xanthomonadales	O	Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_70174_1	1121447.JONL01000001_gene914	1.78e-52	174.0	COG1262@1|root,COG1262@2|Bacteria,1RH9I@1224|Proteobacteria,43DAT@68525|delta/epsilon subdivisions,2X632@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_131222_1	391587.KAOT1_04400	2.36e-19	92.8	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_9282_1	596152.DesU5LDRAFT_0343	2.62e-08	55.5	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,2MB8H@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the carbamate kinase family	cpkA	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_70175_1	187272.Mlg_2399	6.02e-16	80.1	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_70175_2	349741.Amuc_1584	6.55e-19	89.4	COG1459@1|root,COG1459@2|Bacteria,46U60@74201|Verrucomicrobia,2IWMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_63579_1	1121920.AUAU01000016_gene1303	1.8e-31	126.0	2BKCR@1|root,32ETA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212599_1	1121926.AXWO01000005_gene556	1.01e-06	57.4	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4EY9U@85014|Glycomycetales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_97574_1	1049564.TevJSym_ab01010	7.27e-43	146.0	2EQTE@1|root,33ID4@2|Bacteria,1RKB7@1224|Proteobacteria,1S6DN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_97574_2	1049564.TevJSym_ac00040	1.21e-34	125.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria,1JBG1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC-2 family transporter protein	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
k59_185411_2	349521.HCH_01257	5.03e-49	162.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1XKKS@135619|Oceanospirillales	135619|Oceanospirillales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k59_56671_1	2340.JV46_15670	1.99e-103	306.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1J4H1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_56671_2	1283300.ATXB01000001_gene2012	1.22e-30	113.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1XF50@135618|Methylococcales	135618|Methylococcales	F	Phosphoribosyl transferase domain	-	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_144717_1	1117647.M5M_19155	1.5e-26	109.0	COG0329@1|root,COG0379@1|root,COG0329@2|Bacteria,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1J56G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919	NadA
k59_144717_2	556269.ACDQ01000011_gene263	1.78e-05	50.4	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,472BS@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_83939_1	765913.ThidrDRAFT_4284	1.47e-57	191.0	COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1RY54@1236|Gammaproteobacteria,1WWFU@135613|Chromatiales	135613|Chromatiales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase
k59_83939_2	349124.Hhal_0277	1.3e-50	171.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,1S6X5@1236|Gammaproteobacteria,1WY5W@135613|Chromatiales	135613|Chromatiales	O	PFAM NifZ	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k59_131230_1	2340.JV46_25480	3.76e-68	215.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1J4HH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_131230_2	768671.ThimaDRAFT_2658	3.75e-13	67.4	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1WWPI@135613|Chromatiales	135613|Chromatiales	D	TIGRFAM Cell division ATP-binding protein FtsE	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_205939_1	247633.GP2143_04710	1.83e-71	225.0	2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1J5GW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2797)	LA2027	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k59_205939_2	326297.Sama_0429	1.01e-14	70.5	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,2QC18@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF971)	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF971
k59_158466_1	572480.Arnit_1757	5.68e-31	127.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2YN67@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD,Prok-TraM
k59_16116_1	1165841.SULAR_09049	3.96e-11	59.7	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2YPGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	fur	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_16116_2	1165841.SULAR_09054	9.76e-192	543.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_185420_2	498211.CJA_3295	6.28e-14	77.4	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,1FFYV@10|Cellvibrio	1236|Gammaproteobacteria	T	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_19,TPR_2,TPR_8
k59_192357_1	313596.RB2501_03760	6.45e-98	312.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IJBA@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_29687_1	313596.RB2501_11032	1.62e-162	459.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1HXPA@117743|Flavobacteriia	976|Bacteroidetes	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_50183_2	1123247.AUIJ01000012_gene822	2.79e-39	140.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TR8F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_192359_1	767434.Fraau_0843	1.68e-11	66.2	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1X4T1@135614|Xanthomonadales	135614|Xanthomonadales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_192359_2	257310.BB3329	4.48e-12	65.1	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,3T219@506|Alcaligenaceae	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_36297_2	1172190.M947_00845	5.16e-44	157.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_83955_1	1168034.FH5T_04175	2.02e-153	466.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,2FMDI@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_165080_1	1165841.SULAR_03048	5.09e-191	540.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_90785_1	1121912.AUHD01000005_gene1669	1.83e-28	117.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_63590_1	886379.AEWI01000003_gene547	1.18e-54	184.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,2FN75@200643|Bacteroidia,3XK45@558415|Marinilabiliaceae	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_138006_1	2340.JV46_29190	7.15e-255	712.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_90791_1	1515746.HR45_17560	6.3e-28	117.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q9C5@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9,Reg_prop
k59_16133_1	2340.JV46_18500	6.54e-97	305.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J57P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k59_2677_1	1469607.KK073768_gene492	2.22e-50	183.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,Thioesterase
k59_36304_1	756272.Plabr_4269	1.46e-101	309.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
k59_29706_1	1123228.AUIH01000026_gene3895	8.18e-90	277.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1XISZ@135619|Oceanospirillales	135619|Oceanospirillales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_56690_1	2340.JV46_03430	1.9e-66	207.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_97607_1	1165841.SULAR_09114	3.2e-63	199.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_97607_2	1165841.SULAR_09119	4.96e-73	236.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_70223_1	553385.JEMF01000036_gene1114	4.32e-12	69.7	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XH3K@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_70223_2	1128421.JAGA01000001_gene2037	6.22e-09	60.1	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2NRQE@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
k59_2681_1	1165841.SULAR_00525	1.64e-93	274.0	COG1846@1|root,COG1846@2|Bacteria,1ND45@1224|Proteobacteria,42UP2@68525|delta/epsilon subdivisions,2YQ0G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
k59_2681_2	1165841.SULAR_00530	1.11e-117	338.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42RV5@68525|delta/epsilon subdivisions,2YP89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_2681_3	1165841.SULAR_00535	1.53e-23	95.9	COG3384@1|root,COG3384@2|Bacteria,1RB6Z@1224|Proteobacteria,43ACS@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_110982_1	1004149.AFOE01000041_gene1192	7.43e-66	215.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_117922_1	1349767.GJA_2247	3.5e-15	72.8	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VJMC@28216|Betaproteobacteria,472YT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the WrbA family	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
k59_131262_1	1123399.AQVE01000005_gene879	5.01e-77	250.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
k59_63597_1	933262.AXAM01000053_gene2719	1.1e-52	171.0	COG1848@1|root,COG1848@2|Bacteria,1N3CQ@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_131693_1	755178.Cyan10605_2828	3.78e-71	229.0	COG3385@1|root,COG3385@2|Bacteria,1G0M7@1117|Cyanobacteria	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_50511_1	1168034.FH5T_17435	1.98e-22	89.4	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,2FUP5@200643|Bacteroidia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_50511_2	1168034.FH5T_17440	1.79e-53	182.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,2FM0Y@200643|Bacteroidia	976|Bacteroidetes	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k59_63942_1	616991.JPOO01000003_gene2664	2.52e-40	145.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HWYG@117743|Flavobacteriia,23GV8@178469|Arenibacter	976|Bacteroidetes	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_91125_1	237368.SCABRO_01719	6.66e-61	191.0	COG1943@1|root,COG1943@2|Bacteria,2J3NS@203682|Planctomycetes	2|Bacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_199630_1	1165841.SULAR_00425	2.67e-80	254.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_185843_1	1396141.BATP01000030_gene3634	2.45e-06	60.5	COG3170@1|root,COG3210@1|root,COG3866@1|root,COG3170@2|Bacteria,COG3210@2|Bacteria,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	pnlA	-	2.7.7.65,4.2.2.10	ko:K01732,ko:K02316,ko:K13590,ko:K20276,ko:K20541	ko02024,ko03030,ko04112,map02024,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko02000,ko03032	4.D.3.1.6	-	-	DUF3086,Pec_lyase_C,RicinB_lectin_2
k59_192737_1	2340.JV46_16230	3.99e-91	275.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1J4D2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665	Pribosyl_synth,Pribosyltran_N
k59_185847_1	1173028.ANKO01000149_gene5570	2.06e-36	144.0	COG2911@1|root,COG2931@1|root,COG3210@1|root,COG5276@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Big_5,DUF4214,LVIVD,TIG
k59_145319_1	1236542.BALM01000001_gene403	8.38e-22	94.4	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,1RN9P@1236|Gammaproteobacteria,2Q9AS@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_145319_2	1123242.JH636434_gene4156	2.01e-14	74.7	COG3379@1|root,COG3379@2|Bacteria,2J27J@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_77514_1	631362.Thi970DRAFT_04554	2.19e-50	169.0	COG3005@1|root,COG3005@2|Bacteria,1QZ6I@1224|Proteobacteria,1RXZD@1236|Gammaproteobacteria,1X0FD@135613|Chromatiales	135613|Chromatiales	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_77514_2	1123240.ATVO01000009_gene720	2.89e-44	150.0	296YQ@1|root,2ZU7A@2|Bacteria,1RDAE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124983_1	426716.JOAJ01000005_gene2486	6.81e-18	87.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4FTYI@85025|Nocardiaceae	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
k59_57077_1	1165841.SULAR_00695	5.53e-52	182.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2YMYH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_70657_1	1165841.SULAR_00625	2.74e-118	345.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NS3@68525|delta/epsilon subdivisions,2YTNJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_138323_1	998674.ATTE01000001_gene2504	3.12e-12	65.1	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,460Y0@72273|Thiotrichales	72273|Thiotrichales	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
k59_138323_2	1123400.KB904747_gene538	1.02e-12	68.9	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_6674_1	1565129.JSFF01000003_gene2070	6.97e-50	176.0	COG0624@1|root,COG0624@2|Bacteria,1R44A@1224|Proteobacteria,1RZ9X@1236|Gammaproteobacteria,2QAEX@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM peptidase M20	pepV	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_53780_1	234267.Acid_7778	4.66e-24	106.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_135231_1	941449.dsx2_2015	2.54e-34	130.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2M8RD@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_135231_2	283942.IL2139	5.95e-25	100.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,2QG8Z@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
k59_20053_1	1168034.FH5T_11915	3.74e-98	298.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,2FM6G@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_209708_2	1165841.SULAR_00115	1.76e-82	246.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,42RGX@68525|delta/epsilon subdivisions,2YPA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TIGRFAM DJ-1 family protein	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_196172_1	377629.TERTU_2693	3.77e-25	107.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,2PMQ4@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_216341_1	1122179.KB890425_gene3431	1.68e-16	84.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_196177_1	395493.BegalDRAFT_2908	1.44e-94	287.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,46072@72273|Thiotrichales	72273|Thiotrichales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_169222_1	742767.HMPREF9456_01419	3.13e-30	118.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,2FMMD@200643|Bacteroidia,22VXW@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA topoisomerase (ATP-hydrolyzing)	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_94631_1	1123517.JOMR01000001_gene1076	2.22e-50	181.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,461UP@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_101240_1	555779.Dthio_PD0002	4.89e-24	94.4	COG0358@1|root,COG0358@2|Bacteria,1N8NW@1224|Proteobacteria,42WR7@68525|delta/epsilon subdivisions,2WS70@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Zinc finger, CHC2-type protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
k59_101240_2	767817.Desgi_1675	3.87e-11	66.6	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24BFG@186801|Clostridia,263S2@186807|Peptococcaceae	186801|Clostridia	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_73741_1	443143.GM18_2493	1.03e-22	99.8	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_202972_1	1165841.SULAR_08859	3.73e-159	453.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_121801_1	1121447.JONL01000001_gene916	1.27e-66	215.0	COG3344@1|root,COG3344@2|Bacteria,1Q9I9@1224|Proteobacteria,42YRP@68525|delta/epsilon subdivisions,2WU26@28221|Deltaproteobacteria,2M9ZE@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_162231_1	265729.GS18_0216480	7.72e-07	52.0	COG1216@1|root,COG1216@2|Bacteria,1TP40@1239|Firmicutes,4HDDN@91061|Bacilli,1ZE37@1386|Bacillus	91061|Bacilli	S	Glycosyltransferase like family 2	ywdF	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_162231_2	713586.KB900536_gene1008	8.83e-27	106.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria,1WW2H@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM CRISPR-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
k59_216352_1	313596.RB2501_12979	3.04e-62	206.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1HX8F@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
k59_202976_2	998674.ATTE01000001_gene2765	2.83e-35	127.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,460ZV@72273|Thiotrichales	72273|Thiotrichales	NU	PFAM Fimbrial assembly protein (PilN)	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
k59_121812_2	1165841.SULAR_00240	2.67e-144	411.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,42N9H@68525|delta/epsilon subdivisions,2YMGK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_13198_1	1165841.SULAR_05818	2.95e-147	425.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2YMZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_6702_1	1120985.AUMI01000001_gene2158	2.51e-28	119.0	COG3299@1|root,COG3299@2|Bacteria,1TQXP@1239|Firmicutes,4H5RU@909932|Negativicutes	909932|Negativicutes	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_135267_1	313596.RB2501_05700	5.88e-90	271.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1HXJT@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
k59_128332_1	1165841.SULAR_02813	1.09e-105	313.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_26757_2	472759.Nhal_3009	2.28e-39	136.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1WYQ1@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, chi subunit	-	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
k59_26757_3	517433.PanABDRAFT_1536	7.68e-49	169.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,3VXWU@53335|Pantoea	1236|Gammaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_216373_1	29730.Gorai.008G221000.1	3.13e-06	54.3	COG1874@1|root,KOG0496@2759|Eukaryota,37RYU@33090|Viridiplantae,3GH7F@35493|Streptophyta	35493|Streptophyta	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Gal_Lectin,Glyco_hydro_35
k59_20077_1	1165841.SULAR_02268	9.84e-146	419.0	COG2200@1|root,COG2200@2|Bacteria,1NQKX@1224|Proteobacteria,43CB3@68525|delta/epsilon subdivisions,2YTAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,sCache_2
k59_13206_1	395493.BegalDRAFT_1771	3.97e-105	311.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,4605V@72273|Thiotrichales	72273|Thiotrichales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_209739_1	1165841.SULAR_03722	8.97e-125	372.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,42P5S@68525|delta/epsilon subdivisions,2YNR9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	edd	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_81012_1	1443665.JACA01000034_gene2492	4.94e-40	152.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia,2YGPR@290174|Aquimarina	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_135273_1	1168034.FH5T_04125	1.65e-83	262.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,2FNDJ@200643|Bacteroidia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_94651_1	313596.RB2501_07605	5.9e-82	260.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_94651_2	980584.AFPB01000174_gene1562	4.13e-08	56.6	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia,406KS@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_101257_1	1174529.WSI_00725	1.08e-09	65.9	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,4B86G@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_121833_1	2340.JV46_21020	3.57e-142	411.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1J4TX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	iPC815.YPO3376	Enolase_C,Enolase_N
k59_121833_2	384676.PSEEN4199	6.45e-09	54.3	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k59_141854_1	583345.Mmol_1417	2.35e-31	120.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,2KKXM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_182518_2	566461.SSFG_07394	5.1e-11	65.9	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_101258_1	903818.KI912269_gene353	8.57e-21	92.8	2ET40@1|root,33KN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_101258_2	91604.ID47_02365	5.79e-05	42.7	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,47FU0@766|Rickettsiales	766|Rickettsiales	L	Bacterial DNA-binding protein	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_128341_1	1165841.SULAR_06963	7.16e-176	496.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_128341_2	387093.SUN_2056	1.03e-12	66.6	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2YMW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_73779_1	1165841.SULAR_09554	1.23e-115	342.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_189016_2	1165841.SULAR_06033	6.17e-13	67.4	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_216387_1	177437.HRM2_41180	1.64e-25	109.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MIDF@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
k59_39921_1	298386.PBPRA2368	8.18e-31	117.0	COG0666@1|root,COG0666@2|Bacteria,1P2CN@1224|Proteobacteria,1SSTG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142585_1	1165841.SULAR_04492	6.93e-106	321.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_115480_1	1333856.L686_13050	4.15e-23	97.1	COG2863@1|root,COG2863@2|Bacteria,1RC1Y@1224|Proteobacteria,1S9J7@1236|Gammaproteobacteria,1YZSM@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	Cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_81589_2	1117314.PCIT_20544	3.05e-06	48.1	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,2Q05H@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	COG0569 K transport systems, NAD-binding component	trkA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iE2348C_1286.E2348C_3552	TrkA_C,TrkA_N
k59_61257_1	313596.RB2501_12687	4.19e-167	488.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_108677_1	929562.Emtol_0432	5.24e-19	92.4	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,47NK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_34177_2	1168034.FH5T_05905	4.87e-35	124.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,2FU81@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_196822_1	55601.VANGNB10_cII0172	2.72e-51	171.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,1S9F3@1236|Gammaproteobacteria,1XSID@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_115486_1	998088.B565_0359	9.49e-15	75.5	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1Y3PI@135624|Aeromonadales	135624|Aeromonadales	NU	pilus assembly	tapB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_156167_1	1415780.JPOG01000001_gene2437	1.47e-50	181.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X32B@135614|Xanthomonadales	135614|Xanthomonadales	P	COG2217 Cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_156167_2	519989.ECTPHS_06587	6.71e-18	76.6	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria	1224|Proteobacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
k59_128945_2	497321.C664_00585	5.05e-10	64.7	COG5501@1|root,COG5501@2|Bacteria,1PB0I@1224|Proteobacteria,2VNJJ@28216|Betaproteobacteria,2KW2T@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
k59_74776_1	4081.Solyc01g007360.2.1	8.62e-124	353.0	2CNI2@1|root,2QWGG@2759|Eukaryota,37P4I@33090|Viridiplantae,3GGGH@35493|Streptophyta,44MN2@71274|asterids	35493|Streptophyta	S	Ycf4	ycf4	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016043,GO:0019684,GO:0022607,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048564,GO:0051082,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Ycf4
k59_54445_1	1279017.AQYJ01000026_gene178	1.01e-72	241.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,464S9@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_2160,iPC815.YPO2428	B3_4,B5,FDX-ACB,tRNA_bind
k59_13824_1	1304885.AUEY01000040_gene1596	1.13e-64	211.0	COG0500@1|root,COG1047@1|root,COG1047@2|Bacteria,COG2226@2|Bacteria,1PCH2@1224|Proteobacteria,42M58@68525|delta/epsilon subdivisions,2WK5Z@28221|Deltaproteobacteria,2MIYH@213118|Desulfobacterales	28221|Deltaproteobacteria	OQ	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_34185_1	387093.SUN_1350	2.79e-69	230.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_88394_1	1165841.SULAR_01160	1.13e-97	293.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,42PT0@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_7035_1	864051.BurJ1DRAFT_3314	8.36e-102	311.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria,1KK04@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_27418_1	292414.TM1040_1831	1.21e-40	146.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,2TTCR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Protein conserved in bacteria	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF900,Sel1
k59_88406_1	1249627.D779_1971	1.98e-133	389.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_57280_1	1041930.Mtc_1044	6.49e-20	88.6	COG0524@1|root,arCOG00014@2157|Archaea	2157|Archaea	G	Belongs to the carbohydrate kinase PfkB family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704	2.7.1.15,2.7.1.213	ko:K00852,ko:K21057	ko00030,ko00240,map00030,map00240	-	R00513,R00964,R01051,R01666,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_186083_1	768671.ThimaDRAFT_0913	5.47e-57	190.0	2DBUZ@1|root,2ZB8W@2|Bacteria,1QWGF@1224|Proteobacteria,1SN24@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_186083_2	1049564.TevJSym_ac00110	1.02e-53	174.0	COG2863@1|root,COG2863@2|Bacteria,1R6DK@1224|Proteobacteria	1224|Proteobacteria	C	Pfam cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_118619_1	635013.TherJR_1461	5.01e-68	221.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_9921_1	2340.JV46_16680	6.13e-69	214.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	HAD-hyrolase-like	gph	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756	HAD_2
k59_91334_1	580332.Slit_2117	1.5e-68	220.0	COG0475@1|root,COG0475@2|Bacteria,1PK6U@1224|Proteobacteria,2WAEY@28216|Betaproteobacteria,44WJS@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_131924_1	870187.Thini_0307	6.52e-37	131.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_192963_1	1168034.FH5T_06695	7.02e-91	278.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,2FM5E@200643|Bacteroidia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_165693_1	7668.SPU_015791-tr	6.04e-54	188.0	2B36B@1|root,2S0E9@2759|Eukaryota,3A1KW@33154|Opisthokonta,3BSTV@33208|Metazoa,3D7KR@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FLYWCH,MULE
k59_213257_1	746697.Aeqsu_0791	1.25e-42	162.0	COG1629@1|root,COG1629@2|Bacteria,4PM9F@976|Bacteroidetes,1HZ8T@117743|Flavobacteriia	976|Bacteroidetes	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192964_1	948870.I7HXL0_9CAUD	1.26e-09	60.8	4QDCQ@10239|Viruses,4QVJW@35237|dsDNA viruses  no RNA stage,4QPZZ@28883|Caudovirales,4QICG@10662|Myoviridae	10662|Myoviridae	S	Domain of unknown function (DUF1768)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_172621_1	570967.JMLV01000015_gene3109	9.95e-39	136.0	COG4778@1|root,COG4778@2|Bacteria,1MUPB@1224|Proteobacteria,2TR7T@28211|Alphaproteobacteria,2JQAN@204441|Rhodospirillales	204441|Rhodospirillales	P	(ABC transporter), ATP-binding	phnL	-	2.7.8.37	ko:K05780	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	ABC_tran
k59_172621_2	1238182.C882_4270	3.2e-18	84.3	COG3454@1|root,COG3454@2|Bacteria,1MV7H@1224|Proteobacteria,2TQMS@28211|Alphaproteobacteria,2JQEN@204441|Rhodospirillales	204441|Rhodospirillales	P	metal-dependent hydrolase involved in phosphonate metabolism	phnM	-	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_64129_1	488538.SAR116_0987	1.66e-26	112.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2U6XU@28211|Alphaproteobacteria,4BR86@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_3320_1	118161.KB235922_gene396	3.14e-46	158.0	COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_3320_2	1041139.KB902683_gene2761	3.12e-55	190.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_145548_1	1168034.FH5T_06520	1.14e-51	176.0	COG0042@1|root,COG0042@2|Bacteria,4NFRH@976|Bacteroidetes,2FMTW@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_145548_2	1168034.FH5T_06525	2.23e-30	119.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_30435_1	768671.ThimaDRAFT_3757	9.33e-68	224.0	COG0421@1|root,COG0421@2|Bacteria,1QZ2Z@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57293_1	1165841.SULAR_03262	6.78e-91	278.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_192974_1	1121374.KB891579_gene1741	1.68e-20	89.4	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_199872_1	1168034.FH5T_09155	4.95e-59	197.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,2FM0W@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_111559_1	313596.RB2501_06760	2.27e-27	100.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_111559_2	313596.RB2501_06755	1.79e-56	183.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_206553_1	1165841.SULAR_08994	2.46e-84	258.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_98252_1	1165841.SULAR_03188	9.76e-90	272.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_98252_2	387093.SUN_1113	3.18e-18	82.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2YN69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_43593_1	563040.Saut_1309	1.46e-146	429.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_125159_1	1117647.M5M_10760	2.74e-18	83.6	COG1075@1|root,COG1075@2|Bacteria,1NR23@1224|Proteobacteria,1SN18@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	cmfA	-	-	-	-	-	-	-	-	-	-	-	-
k59_57297_1	153948.NAL212_2951	2.79e-59	197.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,2VK8B@28216|Betaproteobacteria,373J4@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_179061_1	391603.FBALC1_00592	9.55e-47	160.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1HYD7@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_192981_2	649764.HMPREF0762_00240	3.14e-22	98.2	COG0558@1|root,COG1546@1|root,COG0558@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4CYG4@84998|Coriobacteriia	84998|Coriobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	cinA	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf,CinA
k59_104904_1	926550.CLDAP_06870	3.37e-12	67.4	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k59_64147_1	2340.JV46_16190	2.15e-128	374.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1J5DE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_118655_1	1408473.JHXO01000014_gene4076	3.45e-43	144.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,2FNF1@200643|Bacteroidia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_118655_2	1168034.FH5T_19620	7.46e-35	119.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,2FUKE@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_132480_1	93220.LV28_15855	1.49e-11	71.6	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,1K124@119060|Burkholderiaceae	28216|Betaproteobacteria	M	lytic transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k59_10324_1	661367.LLO_2437	1.28e-53	186.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria,1JCZW@118969|Legionellales	118969|Legionellales	I	Acyl-CoA dehydrogenase, middle domain	aidB	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
k59_105364_2	1168034.FH5T_12405	2.99e-50	161.0	COG4770@1|root,COG4770@2|Bacteria,4NWQ0@976|Bacteroidetes,2FUXX@200643|Bacteroidia	976|Bacteroidetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
k59_50996_2	519989.ECTPHS_13238	1.68e-29	111.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1WW17@135613|Chromatiales	135613|Chromatiales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_132483_1	1121374.KB891588_gene3405	1.51e-05	49.3	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k59_132483_2	247634.GPB2148_2965	1.18e-31	120.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1J4FB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_173022_1	1121105.ATXL01000004_gene1300	0.000352	43.9	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,4B34E@81852|Enterococcaceae	91061|Bacilli	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_173022_2	1122222.AXWR01000011_gene911	5.92e-18	84.7	COG0343@1|root,COG0343@2|Bacteria,1WI0U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_152768_1	395493.BegalDRAFT_3280	7.36e-90	277.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,45ZVI@72273|Thiotrichales	72273|Thiotrichales	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_23845_1	570952.ATVH01000019_gene727	8.48e-50	172.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,2JW2Q@204441|Rhodospirillales	204441|Rhodospirillales	C	ATP ADP translocase	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_207079_1	4081.Solyc00g014830.2.1	7.61e-56	184.0	COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,3GGWT@35493|Streptophyta	35493|Streptophyta	C	NADH dehydrogenase (Ubiquinone) iron-sulfur protein	nad7	-	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k59_50999_1	1049564.TevJSym_ae00910	1.21e-70	223.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1J4TF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_50999_2	582744.Msip34_1003	8.16e-33	124.0	COG1230@1|root,COG1230@2|Bacteria,1QUZ5@1224|Proteobacteria,2WGMK@28216|Betaproteobacteria,2KMTU@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
k59_119124_1	292415.Tbd_2653	5.85e-63	217.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,2VJGQ@28216|Betaproteobacteria,1KSEQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_3748_2	565045.NOR51B_2646	5.16e-281	774.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1J88Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_78140_1	2340.JV46_24850	2.89e-155	445.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1J5CN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG4992 Ornithine acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_186555_1	2340.JV46_05930	2.69e-45	156.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,1SBTI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_37222_1	1165841.SULAR_04542	8.74e-61	199.0	COG1538@1|root,COG1538@2|Bacteria,1PBTH@1224|Proteobacteria,42R59@68525|delta/epsilon subdivisions,2YP2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_111916_1	1165841.SULAR_08442	1.88e-120	355.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_111916_2	1165841.SULAR_08437	7.1e-67	203.0	COG0011@1|root,COG0011@2|Bacteria,1N0UT@1224|Proteobacteria,43B8R@68525|delta/epsilon subdivisions,2YT6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_119142_1	397945.Aave_3295	8.22e-67	229.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,4A9UC@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_44025_1	1499967.BAYZ01000032_gene1153	4.19e-25	103.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2NQ28@2323|unclassified Bacteria	2|Bacteria	L	Integrase core domain	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_28,HTH_Tnp_1,rve,rve_3
k59_44025_2	1137799.GZ78_14485	3.5e-102	305.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_78156_1	395493.BegalDRAFT_0309	7.59e-19	84.3	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,1S32B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_30852_1	395493.BegalDRAFT_0704	1.57e-96	305.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_139092_1	395493.BegalDRAFT_0882	1.81e-62	212.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,1RSJ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
k59_53131_1	1165841.SULAR_09474	4.03e-148	421.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2YM85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_N
k59_53131_2	1165841.SULAR_09479	2.8e-17	80.1	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_181845_1	1168034.FH5T_01865	1.87e-47	166.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
k59_19487_1	1366050.N234_15805	5.38e-49	174.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria,1K2M0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_39264_1	313596.RB2501_00181	6.99e-14	68.6	28P9K@1|root,2ZC31@2|Bacteria,4NPW6@976|Bacteroidetes,1I1KA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
k59_39264_2	867900.Celly_0150	5.14e-46	152.0	COG1413@1|root,COG1413@2|Bacteria,4NUQJ@976|Bacteroidetes,1I52N@117743|Flavobacteriia,1F9KK@104264|Cellulophaga	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_209172_1	278963.ATWD01000002_gene278	2.39e-22	106.0	COG0515@1|root,COG0515@2|Bacteria,3Y6SR@57723|Acidobacteria,2JP6D@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_113703_1	1392498.JQLH01000001_gene3272	5.03e-08	55.5	2CIT3@1|root,32Y0C@2|Bacteria,4NUWR@976|Bacteroidetes,1I533@117743|Flavobacteriia,2PHN7@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
k59_26030_1	1120977.JHUX01000003_gene1442	2.76e-20	83.2	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,3NNW8@468|Moraxellaceae	1236|Gammaproteobacteria	KL	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	fis	GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
k59_26030_2	1120970.AUBZ01000029_gene1066	2.49e-61	204.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,4646Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	purH	GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcHS_1320.EcHS_A4240,iPC815.YPO3728	AICARFT_IMPCHas,MGS
k59_32972_1	153721.MYP_485	1.72e-32	134.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k59_148335_2	396588.Tgr7_0944	1.12e-160	459.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1WXTC@135613|Chromatiales	135613|Chromatiales	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_168507_1	1168034.FH5T_01400	1.73e-102	309.0	COG2304@1|root,COG2304@2|Bacteria,4NFNQ@976|Bacteroidetes,2FMMK@200643|Bacteroidia	976|Bacteroidetes	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
k59_46454_1	1268237.G114_04253	2.88e-26	110.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1Y3NX@135624|Aeromonadales	135624|Aeromonadales	M	penicillin-binding protein 1A	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_195628_1	247634.GPB2148_778	4.64e-96	295.0	COG2010@1|root,COG3420@1|root,COG2010@2|Bacteria,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,1T2I7@1236|Gammaproteobacteria,1J4SI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3420 Nitrous oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
k59_80287_2	765913.ThidrDRAFT_3933	3.32e-67	208.0	COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1WY49@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_80287_3	1260251.SPISAL_02455	2.64e-31	115.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1WWW9@135613|Chromatiales	135613|Chromatiales	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	-	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
k59_209180_1	1123248.KB893348_gene369	2.7e-70	239.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_60164_1	395493.BegalDRAFT_0766	1.11e-97	306.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	3.1.4.52	ko:K21024	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_8,PAS_9
k59_94016_1	349521.HCH_05841	7.33e-14	71.6	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1XIS6@135619|Oceanospirillales	135619|Oceanospirillales	M	Lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_94016_2	2340.JV46_11170	2.17e-112	335.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1J4UD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S11 family	dacA	GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664	PBP5_C,Peptidase_S11
k59_148350_1	1121904.ARBP01000030_gene1961	1.6e-71	227.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,47K0T@768503|Cytophagia	976|Bacteroidetes	S	alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_46465_1	247634.GPB2148_1865	3e-34	129.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1J6F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1566 Multidrug resistance efflux pump	VVA0148	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_94020_1	1165841.SULAR_08055	6.04e-27	105.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	MORN_2,TonB_C
k59_108193_2	1589733.A0A0C5AIT1_9CAUD	6.37e-06	48.5	4QAQQ@10239|Viruses,4QPBX@28883|Caudovirales,4QIBM@10662|Myoviridae	10662|Myoviridae	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94453_1	2340.JV46_05080	4.84e-42	149.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1J7WK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_141622_1	1215114.BBIU01000023_gene2941	6.77e-37	136.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_202749_1	1144275.COCOR_03928	4.58e-145	471.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions,2X7UA@28221|Deltaproteobacteria,2Z3KU@29|Myxococcales	28221|Deltaproteobacteria	IQ	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_155254_1	269084.syc1395_c	8.1e-65	203.0	COG0783@1|root,COG0783@2|Bacteria,1G586@1117|Cyanobacteria,1H0B1@1129|Synechococcus	1117|Cyanobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k59_175731_1	1165841.SULAR_06123	1.95e-29	115.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_175731_2	1165841.SULAR_06128	5.75e-84	252.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2YPMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_175731_3	1165841.SULAR_06133	1.2e-08	52.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2YPU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_182282_1	323848.Nmul_A1673	1.09e-39	147.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,372TK@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Nickel-dependent hydrogenase	hoxH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_169024_2	1121935.AQXX01000081_gene1113	3.24e-25	108.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XHAT@135619|Oceanospirillales	135619|Oceanospirillales	T	GAF domain	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_12938_1	768066.HELO_4445	3.21e-77	240.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XHVC@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_175736_1	387093.SUN_2273	1.33e-65	206.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_182286_1	1123326.JFBL01000004_gene2039	9.36e-33	121.0	2AJE1@1|root,319ZU@2|Bacteria,1Q4J6@1224|Proteobacteria,42U7R@68525|delta/epsilon subdivisions,2YQ63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12942_2	1144275.COCOR_06627	2.98e-54	186.0	COG1061@1|root,COG1061@2|Bacteria,1NF8B@1224|Proteobacteria,42VEZ@68525|delta/epsilon subdivisions,2WSK2@28221|Deltaproteobacteria,2YU59@29|Myxococcales	28221|Deltaproteobacteria	L	ERCC3/RAD25/XPB C-terminal helicase	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,ResIII
k59_188779_1	1537917.JU82_02905	1.63e-38	135.0	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_188779_2	1165841.SULAR_08582	3.7e-08	53.9	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,42P57@68525|delta/epsilon subdivisions,2YMGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_33390_1	1120965.AUBV01000005_gene1867	2.12e-111	336.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47JC1@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_141634_1	1121346.KB899827_gene490	5.95e-89	278.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,26R94@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_195981_1	62977.ACIAD1232	5.09e-16	73.6	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,3NNJH@468|Moraxellaceae	1236|Gammaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin,Rhodanese
k59_202757_1	1121875.KB907551_gene1027	2.22e-87	280.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IJ85@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3
k59_53599_1	387093.SUN_0974	3.78e-109	328.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42NGE@68525|delta/epsilon subdivisions,2YN37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_175742_1	1165841.SULAR_01573	1.31e-28	110.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42YUF@68525|delta/epsilon subdivisions,2YR9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_73623_1	1165841.SULAR_07680	1.01e-154	445.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2YMC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_155264_1	1121859.KB890738_gene3302	2.37e-11	66.2	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47K5R@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_101098_1	1348583.ATLH01000022_gene2399	1.09e-78	244.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia,1F8K2@104264|Cellulophaga	976|Bacteroidetes	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_195985_1	44251.PDUR_11270	4.59e-69	230.0	COG0331@1|root,COG2070@1|root,COG0331@2|Bacteria,COG2070@2|Bacteria,1UG0E@1239|Firmicutes,4HE1K@91061|Bacilli,26RF2@186822|Paenibacillaceae	91061|Bacilli	I	Malonyl CoA-acyl carrier protein transacylase	pfaD	-	-	ko:K15329	-	-	-	-	ko00000,ko01008	-	-	-	Acyl_transf_1,NMO
k59_101102_1	742766.HMPREF9455_00522	1.38e-18	84.7	COG5293@1|root,COG5293@2|Bacteria,4P0PX@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised protein conserved in bacteria (DUF2326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2326
k59_101102_2	742766.HMPREF9455_00521	2.63e-22	88.6	2E3PI@1|root,32YMM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_101102_3	742766.HMPREF9455_00520	1.22e-39	142.0	COG0457@1|root,COG0457@2|Bacteria,4PNY7@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141646_1	1165841.SULAR_06288	5.83e-12	64.7	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_141646_2	1165841.SULAR_06283	2.77e-76	241.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_94472_1	1300345.LF41_142	4.13e-72	238.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1X3NX@135614|Xanthomonadales	135614|Xanthomonadales	O	ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_101103_1	1260251.SPISAL_07280	1.35e-47	158.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1WYGP@135613|Chromatiales	135613|Chromatiales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_53614_1	556269.ACDQ01000016_gene528	7.69e-17	82.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,472HU@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_12962_1	1121403.AUCV01000002_gene644	9.87e-89	276.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,43AXP@68525|delta/epsilon subdivisions,2X6BV@28221|Deltaproteobacteria,2MPWC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_73629_1	50452.A0A087HJ07	4.74e-48	166.0	COG2513@1|root,KOG1260@2759|Eukaryota,37HN9@33090|Viridiplantae,3GD3G@35493|Streptophyta,3HNQU@3699|Brassicales	35493|Streptophyta	C	Carboxyvinyl-carboxyphosphonate phosphorylmutase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	PEP_mutase
k59_195996_1	1049564.TevJSym_aw00120	4.78e-16	77.4	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1J5XD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	dsrL	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Fer4_9,NADH_4Fe-4S,Pyr_redox_2
k59_209531_1	1123073.KB899242_gene1678	3.93e-49	174.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1X4K6@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	gatAX	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,Lipocalin_5
k59_149178_1	1463821.JOGR01000015_gene3506	7.91e-07	55.5	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4EZIY@85014|Glycomycetales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
k59_47529_1	1105367.CG50_09015	4.24e-95	293.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_61074_2	411490.ANACAC_00783	1.51e-49	174.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia	186801|Clostridia	S	Phage terminase, large subunit, PBSX family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k59_135614_1	631362.Thi970DRAFT_02291	2.01e-126	385.0	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales	135613|Chromatiales	M	HAD-superfamily hydrolase, subfamily IIB	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
k59_101754_1	713587.THITH_06955	1.76e-40	145.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WXJB@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_128856_1	1123070.KB899249_gene350	2.81e-88	278.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_122070_1	1163745.HCD_08330	3.99e-54	183.0	COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,42U0V@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k59_40752_1	29760.VIT_03s0038g02780.t01	6.18e-60	184.0	COG0089@1|root,2S1Z9@2759|Eukaryota,37VSJ@33090|Viridiplantae,3GJY5@35493|Streptophyta	35493|Streptophyta	J	ribosomal protein L23	rpl23	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_40752_2	3712.Bo1g034570.1	4.89e-82	258.0	COG0090@1|root,KOG0438@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,3I1MH@3699|Brassicales	35493|Streptophyta	J	Ribosomal Proteins L2, C-terminal domain	rpl2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C,Ribosomal_S19
k59_40752_3	57918.XP_004309313.1	2.29e-104	303.0	COG0090@1|root,KOG0438@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,4JTF7@91835|fabids	35493|Streptophyta	J	50S ribosomal protein	rpl2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C,Ribosomal_S19
k59_40752_4	3880.AES87793	1.94e-34	128.0	COG0090@1|root,COG0185@1|root,KOG0438@2759|Eukaryota,KOG0899@2759|Eukaryota,37SZP@33090|Viridiplantae,3GDE2@35493|Streptophyta,4JTF7@91835|fabids	35493|Streptophyta	J	50S ribosomal protein	rpl2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C,Ribosomal_S19
k59_40752_5	4081.Solyc01g007610.2.1	7.34e-66	211.0	COG0091@1|root,KOG1711@2759|Eukaryota,3842X@33090|Viridiplantae,3GW7N@35493|Streptophyta,44TSR@71274|asterids	35493|Streptophyta	J	Ribosomal protein L22p/L17e	-	GO:0000313,GO:0000315,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_40752_6	3983.cassava4.1_020914m	9.11e-132	376.0	COG0092@1|root,2QV63@2759|Eukaryota,37ITR@33090|Viridiplantae,3GH7T@35493|Streptophyta,4JSQ4@91835|fabids	35493|Streptophyta	J	Belongs to the universal ribosomal protein uS3 family	rps3	GO:0002181,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3_C
k59_183078_1	1349820.M707_14410	3.21e-17	84.7	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,1W87X@1268|Micrococcaceae	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_40753_1	1249627.D779_0110	7.89e-71	237.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1WX68@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_88194_1	395493.BegalDRAFT_3262	9.19e-84	252.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,460EK@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_40755_1	756067.MicvaDRAFT_4072	6.09e-22	103.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_13640_1	204669.Acid345_4155	5.6e-22	100.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
k59_196646_1	1356854.N007_18685	1.17e-61	207.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli	91061|Bacilli	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_149197_1	1242864.D187_009792	9.72e-77	244.0	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,42M4B@68525|delta/epsilon subdivisions,2WJDI@28221|Deltaproteobacteria,2Z03B@29|Myxococcales	28221|Deltaproteobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_13645_1	1123366.TH3_08264	9.48e-06	51.6	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,2JVDV@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_108536_1	616991.JPOO01000001_gene4482	2.58e-48	164.0	COG1595@1|root,COG1595@2|Bacteria,4NGYM@976|Bacteroidetes,1I0GZ@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
k59_54295_1	985255.APHJ01000039_gene235	1.23e-28	103.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia,2P6YV@244698|Gillisia	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_54295_2	1233950.IW22_15295	9.01e-23	92.0	COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,1II63@117743|Flavobacteriia,3ZS22@59732|Chryseobacterium	976|Bacteroidetes	S	RNA-binding protein	ykfA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_54295_3	1433126.BN938_2412	5.02e-36	128.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,2FSAQ@200643|Bacteroidia,22VE8@171550|Rikenellaceae	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
k59_189880_1	1396858.Q666_02180	1.21e-30	115.0	COG4566@1|root,COG4566@2|Bacteria,1R496@1224|Proteobacteria,1SKGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_189880_2	394221.Mmar10_0334	6.91e-07	52.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_16,TPR_8,Trans_reg_C
k59_67875_1	99598.Cal7507_1937	3.76e-46	152.0	COG2442@1|root,COG2442@2|Bacteria,1G60U@1117|Cyanobacteria,1HNJ9@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
k59_67875_2	999423.HMPREF9161_01872	5.3e-39	138.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes	1239|Firmicutes	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_183084_1	1205680.CAKO01000002_gene2222	1.69e-31	129.0	COG1409@1|root,COG1409@2|Bacteria,1R8W7@1224|Proteobacteria,2U64B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_109_1	1165841.SULAR_04853	4.33e-105	333.0	COG2911@1|root,COG2911@2|Bacteria,1PBYT@1224|Proteobacteria,42T65@68525|delta/epsilon subdivisions,2YPPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k59_33999_2	1216966.BAUC01000023_gene1607	2.8e-15	74.7	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_115335_2	344747.PM8797T_32265	9.76e-15	77.8	COG1721@1|root,COG1721@2|Bacteria,2IY8R@203682|Planctomycetes	203682|Planctomycetes	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_122081_1	985054.JQEZ01000001_gene2689	2.01e-05	48.9	COG2197@1|root,COG2197@2|Bacteria,1RA3V@1224|Proteobacteria,2U0I0@28211|Alphaproteobacteria,4NB51@97050|Ruegeria	28211|Alphaproteobacteria	T	Response regulator	kdpE	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_122081_2	1101188.KI912155_gene3190	2.3e-06	51.6	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	devS	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
k59_156012_1	472759.Nhal_0338	2.95e-49	162.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1WY5Q@135613|Chromatiales	135613|Chromatiales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_94995_1	243233.MCA1434	5.58e-33	127.0	COG1215@1|root,COG1215@2|Bacteria,1PU38@1224|Proteobacteria,1RUPG@1236|Gammaproteobacteria,1XGIH@135618|Methylococcales	135618|Methylococcales	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_101787_1	1123377.AUIV01000009_gene2584	3.28e-25	107.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1X774@135614|Xanthomonadales	135614|Xanthomonadales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210226_1	243233.MCA0982	5.62e-10	61.2	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1XFEK@135618|Methylococcales	135618|Methylococcales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_20451_1	1329516.JPST01000003_gene1026	7.91e-24	100.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,27BA9@186824|Thermoactinomycetaceae	91061|Bacilli	E	Aminomethyltransferase folate-binding domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_6875_1	395493.BegalDRAFT_0531	3.7e-66	226.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales	72273|Thiotrichales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_142422_1	1165841.SULAR_00565	8.87e-62	202.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42Z72@68525|delta/epsilon subdivisions,2YRGJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_210229_1	1049564.TevJSym_as00080	5.17e-53	174.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1J4YB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126,SHOCT
k59_135656_1	395493.BegalDRAFT_1126	1.82e-48	177.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_128879_1	1049564.TevJSym_ab01210	3.29e-79	260.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1J5MR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Pyruvate phosphate dikinase	ppdK	-	2.7.3.9,2.7.9.1,2.7.9.2	ko:K01006,ko:K01007,ko:K08483	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00710,map00720,map01100,map01120,map01200,map02060	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_13672_1	926549.KI421517_gene3944	4.97e-74	237.0	COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,47JW2@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_27218_1	633149.Bresu_3070	3.48e-11	62.8	COG3861@1|root,COG3861@2|Bacteria,1NU42@1224|Proteobacteria,2TTV5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	photosynthetic reaction center H subunit	puhA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464	-	ko:K13991	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	PRC,PRCH
k59_27218_2	566466.NOR53_2009	9.87e-37	131.0	COG3428@1|root,COG3428@2|Bacteria,1RHA4@1224|Proteobacteria,1S2AV@1236|Gammaproteobacteria,1J8EN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
k59_88233_1	1121861.KB899914_gene2015	7.14e-65	205.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,2JPS6@204441|Rhodospirillales	204441|Rhodospirillales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_88233_2	266748.HY04_00840	2.12e-47	175.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia,3ZQX9@59732|Chryseobacterium	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_40771_1	648885.KB316282_gene346	4.3e-79	257.0	COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1MV41@1224|Proteobacteria,2TQXP@28211|Alphaproteobacteria,1JZHZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	ko:K02613,ko:K07006	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,Putative_PNPOx
k59_135657_1	1292034.OR37_01315	5.2e-45	159.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2TSP6@28211|Alphaproteobacteria,2KGH8@204458|Caulobacterales	204458|Caulobacterales	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_6879_1	156889.Mmc1_2223	8.55e-27	107.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2U613@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Ubie_methyltran
k59_6879_2	243365.CV_3366	5.98e-06	47.8	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2VTX9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_D
k59_13679_1	566466.NOR53_2733	1.78e-66	220.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1J531@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	M COG4775 Outer membrane protein protective antigen OMA87	tamA	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
k59_6881_1	1168034.FH5T_15380	3.25e-20	87.8	COG0167@1|root,COG0167@2|Bacteria,4NF4D@976|Bacteroidetes,2FM0X@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate	preA	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_6881_2	1168034.FH5T_15375	3.95e-71	220.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,2FM94@200643|Bacteroidia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_115359_1	1535422.ND16A_0507	8.85e-31	122.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,2Q668@267889|Colwelliaceae	1236|Gammaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_34025_1	1049564.TevJSym_aa00440	7.02e-33	129.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1J53Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_74668_1	1168034.FH5T_08440	7.87e-53	186.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia	976|Bacteroidetes	P	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_81468_1	944546.ABED_1649	6.64e-65	208.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2YNH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_210241_1	289377.HL41_01235	4.73e-17	84.0	COG0084@1|root,COG0084@2|Bacteria,2GH9G@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_210241_2	391625.PPSIR1_30691	9.06e-15	74.3	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2WNBT@28221|Deltaproteobacteria,2YWBW@29|Myxococcales	28221|Deltaproteobacteria	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k59_189901_1	1283300.ATXB01000001_gene1274	8.85e-13	73.6	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1XDT5@135618|Methylococcales	135618|Methylococcales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_189903_2	1123279.ATUS01000005_gene3217	8.14e-07	50.1	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S4CK@1236|Gammaproteobacteria,1J6F9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
k59_196693_1	857087.Metme_2103	2.17e-70	222.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RQZ9@1236|Gammaproteobacteria,1XG3E@135618|Methylococcales	135618|Methylococcales	E	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_189906_1	452471.Aasi_1225	7.93e-58	191.0	COG3039@1|root,COG3039@2|Bacteria,4NP0I@976|Bacteroidetes,47XTF@768503|Cytophagia	976|Bacteroidetes	L	GENE3D G3DSA 1.25.40.20, Ankyrin	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
k59_149_1	2340.JV46_18750	1.02e-34	132.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1J5FM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Malic enzyme, NAD binding domain	maeA	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_149_2	2340.JV46_18900	2.42e-39	133.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Pfam Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_81471_1	1165841.SULAR_08347	1.16e-118	361.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_131152_1	4081.Solyc01g007640.2.1	0.0	960.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_50118_1	313596.RB2501_06870	3.14e-80	268.0	COG2373@1|root,COG3209@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SprB
k59_70094_1	313596.RB2501_08930	1.38e-48	159.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1I35P@117743|Flavobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
k59_70094_2	1250232.JQNJ01000001_gene791	3.9e-29	115.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_90679_1	1541065.JRFE01000058_gene5641	1.24e-17	87.8	COG2812@1|root,COG2812@2|Bacteria,1G4SF@1117|Cyanobacteria,3VNKI@52604|Pleurocapsales	1117|Cyanobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_131154_2	1165841.SULAR_09454	4.28e-44	148.0	COG0115@1|root,COG0115@2|Bacteria,1N3ZD@1224|Proteobacteria,42TNN@68525|delta/epsilon subdivisions,2YPU5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Branched-chain amino acid aminotransferase	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k59_104202_1	1165841.SULAR_05623	2.03e-100	296.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2YMS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the TtcA family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_104202_2	1165841.SULAR_05628	3.16e-06	47.8	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,42MBG@68525|delta/epsilon subdivisions,2YMHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	pfs	-	3.2.2.30,3.2.2.9	ko:K18284	ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R10668	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_16039_1	1168034.FH5T_06685	6.35e-82	253.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,2FNVF@200643|Bacteroidia	976|Bacteroidetes	L	COG NOG11654 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
k59_124466_1	387092.NIS_0667	2.5e-10	60.8	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_124466_2	1165841.SULAR_00100	1.38e-73	236.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_2570_1	1165841.SULAR_04227	1.29e-57	186.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42MJP@68525|delta/epsilon subdivisions,2YMVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	pglG	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_2570_2	1165841.SULAR_04232	4.72e-61	194.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2YNM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_110928_1	1313421.JHBV01000143_gene1146	6.83e-25	108.0	COG0433@1|root,COG0433@2|Bacteria,4NVJM@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
k59_63516_1	643867.Ftrac_0606	1.75e-20	88.2	COG2963@1|root,COG2963@2|Bacteria,4NQ8V@976|Bacteroidetes,47RTS@768503|Cytophagia	976|Bacteroidetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_63516_2	1123234.AUKI01000003_gene173	1.82e-43	151.0	COG2801@1|root,COG2801@2|Bacteria,4NRIR@976|Bacteroidetes,1I4VB@117743|Flavobacteriia	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_77033_1	3880.AES58561	3.8e-11	60.5	2E0M5@1|root,2S818@2759|Eukaryota,37X5I@33090|Viridiplantae,3GM26@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43001_2	1278971.AOGF01000002_gene1272	2.17e-07	55.8	COG0500@1|root,COG0500@2|Bacteria,1QUI2@1224|Proteobacteria,1RQ53@1236|Gammaproteobacteria,1YAZ0@135625|Pasteurellales	135625|Pasteurellales	Q	Protein of unknown function (DUF1698)	Z012_09430	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_63518_1	1123393.KB891326_gene144	3.57e-50	177.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k59_36225_1	1144307.PMI04_00097	9.17e-43	157.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2TT66@28211|Alphaproteobacteria,2K0GA@204457|Sphingomonadales	204457|Sphingomonadales	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k59_212553_1	392499.Swit_5197	3.22e-42	153.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,2K3NU@204457|Sphingomonadales	204457|Sphingomonadales	L	Protein involved in DNA binding and transposition, DNA-mediated	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_165029_1	3880.AES58569	4.35e-12	65.1	2E724@1|root,2SDQ0@2759|Eukaryota,37XK8@33090|Viridiplantae,3GMV1@35493|Streptophyta	3880.AES58569|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70126_1	383372.Rcas_4158	5.87e-28	115.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_192282_1	1165841.SULAR_08387	4.84e-108	318.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2YMCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_131175_1	203124.Tery_1091	1.02e-06	58.9	COG4675@1|root,COG4675@2|Bacteria,1G8V2@1117|Cyanobacteria	1117|Cyanobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_63525_1	386415.NT01CX_2320	1.62e-44	168.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_22781_1	1379270.AUXF01000001_gene1944	1.04e-34	143.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
k59_56627_1	1196322.A370_00593	1.25e-61	211.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_199252_1	478801.Ksed_07840	1.07e-24	100.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,1ZVHJ@145357|Dermacoccaceae	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_97533_1	1158762.KB898044_gene332	1.04e-52	178.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_97533_2	519989.ECTPHS_06737	1.86e-38	141.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales	135613|Chromatiales	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,RLAN,RimK
k59_199259_1	395493.BegalDRAFT_3503	1.22e-30	122.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24,TIR_2
k59_144674_1	395493.BegalDRAFT_1428	4.13e-05	45.1	2E4CH@1|root,32Z7Y@2|Bacteria,1NBRN@1224|Proteobacteria,1SCB9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	pilus assembly protein, PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_205901_1	1231391.AMZF01000002_gene3221	3e-35	129.0	COG1309@1|root,COG1309@2|Bacteria,1N014@1224|Proteobacteria,2VVAF@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_70146_1	1165841.SULAR_00845	9.16e-62	194.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2YMH3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_70146_2	1165841.SULAR_00850	9.99e-134	396.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_212578_1	1165841.SULAR_09629	5.86e-106	317.0	COG0025@1|root,COG0025@2|Bacteria,1QHRZ@1224|Proteobacteria,42RU2@68525|delta/epsilon subdivisions,2YPAV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0025 NhaP-type Na H and K H	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	GGDEF,Na_H_Exchanger
k59_171965_2	1957.JODX01000018_gene1679	2.05e-06	51.6	COG1878@1|root,COG1878@2|Bacteria,2ICNS@201174|Actinobacteria	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k59_36246_1	868595.Desca_1703	6.13e-36	142.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_104231_1	29730.Gorai.001G163400.1	1.58e-84	267.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,3GBUN@35493|Streptophyta	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k59_50152_1	502025.Hoch_0458	4.18e-84	276.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,438QJ@68525|delta/epsilon subdivisions,2X3XW@28221|Deltaproteobacteria,2YXIE@29|Myxococcales	28221|Deltaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
k59_178543_1	1123355.JHYO01000013_gene1073	2.25e-75	246.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_137989_1	1165841.SULAR_00370	1.12e-127	379.0	COG0790@1|root,COG0790@2|Bacteria,1Q4TH@1224|Proteobacteria,42ZV8@68525|delta/epsilon subdivisions,2YRWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70152_1	388413.ALPR1_11965	3.99e-115	352.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47TP1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_145212_2	1168034.FH5T_04920	1.93e-104	305.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_212950_1	5932.XP_004034721.1	5.16e-25	108.0	COG1748@1|root,KOG0172@2759|Eukaryota,3ZBJ2@5878|Ciliophora	5878|Ciliophora	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.5.1.8,1.5.1.9	ko:K14157	ko00310,ko01100,ko01110,ko01130,map00310,map01100,map01110,map01130	M00032	R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_N,Saccharop_dh_N
k59_118292_1	1249627.D779_0282	1.44e-117	349.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_57012_1	1265505.ATUG01000002_gene1210	8.49e-101	309.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MJ1V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_124881_2	319225.Plut_0143	9.33e-06	53.5	COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1FEC3@1090|Chlorobi	1090|Chlorobi	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
k59_124881_3	710687.KI912270_gene5312	5.96e-18	85.1	COG1028@1|root,COG1028@2|Bacteria,2I9KN@201174|Actinobacteria,232MV@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	short-chain dehydrogenase	-	-	1.1.1.140	ko:K00068	ko00051,map00051	-	R05607	RC00085	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_118298_1	1267535.KB906767_gene2200	1.28e-69	228.0	COG0473@1|root,COG0473@2|Bacteria,3Y3BC@57723|Acidobacteria,2JKC7@204432|Acidobacteriia	204432|Acidobacteriia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_3027_1	1096756.ATKN01000003_gene1676	1.96e-21	95.1	COG0351@1|root,COG0819@1|root,COG0351@2|Bacteria,COG0819@2|Bacteria,2GKZM@201174|Actinobacteria,1W81E@1268|Micrococcaceae	201174|Actinobacteria	HK	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TENA_THI-4,TMP-TENI
k59_3027_2	40373.F991_01673	0.000129	44.3	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,3NK3G@468|Moraxellaceae	1236|Gammaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_2002,iYL1228.KPN_01074	Amidohydro_1
k59_63890_1	1168034.FH5T_01725	4.08e-41	140.0	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes	976|Bacteroidetes	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_63890_2	1168034.FH5T_01720	1.01e-34	125.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Lipase_GDSL_2,Phosphodiest,SLH
k59_131637_1	96561.Dole_2349	2.69e-27	110.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MHSV@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_165380_1	1408473.JHXO01000006_gene1212	4.53e-62	202.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_3029_1	1283300.ATXB01000001_gene213	1.77e-31	122.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,1S4XC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_131640_1	1111730.ATTM01000004_gene2022	2.48e-145	421.0	COG0753@1|root,COG0753@2|Bacteria,4NFQX@976|Bacteroidetes,1HWVN@117743|Flavobacteriia,2NTPG@237|Flavobacterium	976|Bacteroidetes	P	Serves to protect cells from the toxic effects of hydrogen peroxide	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
k59_54857_1	388413.ALPR1_21088	9.42e-26	115.0	COG1361@1|root,COG3210@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11
k59_618_1	1168034.FH5T_22130	2.84e-116	358.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,2FM9F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54858_1	1177179.A11A3_00700	2.22e-86	263.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,1XJAX@135619|Oceanospirillales	135619|Oceanospirillales	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_14228_1	861208.AGROH133_13021	1.92e-31	118.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,4B85J@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k59_14228_2	205918.Psyr_2955	7.05e-36	126.0	COG2259@1|root,COG2259@2|Bacteria,1N06A@1224|Proteobacteria,1S92U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_170038_2	526218.Sterm_2599	1.15e-11	73.2	COG3950@1|root,COG3950@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
k59_122625_1	746697.Aeqsu_3067	9.21e-123	360.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1HXKR@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_122625_2	1121875.KB907548_gene1691	8.41e-06	47.8	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_190482_1	215803.DB30_0041	1.65e-32	128.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2YYVN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
k59_170039_1	1121918.ARWE01000001_gene216	1.22e-46	172.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,43RYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RadC,ResIII
k59_197223_1	1123257.AUFV01000008_gene627	1.59e-131	387.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1X35C@135614|Xanthomonadales	135614|Xanthomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k59_34545_1	631362.Thi970DRAFT_03548	1.87e-30	112.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1WY5S@135613|Chromatiales	135613|Chromatiales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_34545_2	1286171.EAL2_c13310	1.54e-25	102.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,25VD6@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_41282_1	1168034.FH5T_10910	2.08e-129	378.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,2FMTV@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_156583_1	393480.FNP_0431	8.98e-29	115.0	COG3315@1|root,COG3315@2|Bacteria,379R6@32066|Fusobacteria	32066|Fusobacteria	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LCM
k59_142948_1	1223523.H340_30743	2.61e-63	204.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria	201174|Actinobacteria	J	Phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k59_7353_1	2340.JV46_17750	0.000184	43.5	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1J9QP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Aminotransferase class I and II	hisC	GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECO111_1330.ECO111_2745,iSDY_1059.SDY_2220,iSSON_1240.SSON_2092	Aminotran_1_2
k59_7353_2	2340.JV46_17520	5.53e-125	363.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,1J8D6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	ThiI,tRNA_Me_trans
k59_68450_1	1165841.SULAR_08462	3.42e-103	304.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2YMHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_68450_2	1165841.SULAR_08457	2.2e-101	302.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2YMMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_95499_1	1165841.SULAR_09689	2.95e-111	328.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2YMRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_27788_1	1121875.KB907549_gene2050	4.54e-123	357.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1HWWI@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	tktC	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_156591_1	349124.Hhal_1972	1.28e-52	170.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1WY7B@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
k59_156591_2	272942.RCAP_rcc03282	2.08e-13	71.2	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2UPE8@28211|Alphaproteobacteria,1FCGM@1060|Rhodobacter	28211|Alphaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_102363_1	926556.Echvi_4196	6.69e-92	276.0	COG3039@1|root,COG3039@2|Bacteria,4NGY9@976|Bacteroidetes,47Q0A@768503|Cytophagia	976|Bacteroidetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
k59_633_1	387093.SUN_0512	1.64e-54	181.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1N7HT@1224|Proteobacteria,42RFF@68525|delta/epsilon subdivisions,2YP9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_129389_1	1165841.SULAR_08247	1.21e-30	125.0	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34566_1	398578.Daci_3774	4.02e-61	204.0	COG0443@1|root,COG0443@2|Bacteria,1MUR1@1224|Proteobacteria,2VM1B@28216|Betaproteobacteria,4AD2F@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Heat shock protein 70	hscC	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k59_115901_1	1112214.AHIS01000002_gene1823	1.04e-31	124.0	COG0726@1|root,COG0726@2|Bacteria,1RFCG@1224|Proteobacteria,2U92E@28211|Alphaproteobacteria,2K4B9@204457|Sphingomonadales	204457|Sphingomonadales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_61672_1	765911.Thivi_2848	5.38e-32	113.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales	135613|Chromatiales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_27802_1	313596.RB2501_16139	1.91e-187	532.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_82022_1	1121920.AUAU01000006_gene274	6.72e-60	208.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_210825_1	1168034.FH5T_06525	3.8e-104	328.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_197246_1	483219.LILAB_18035	6.96e-44	151.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria	1224|Proteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
k59_129392_1	2340.JV46_05330	4.95e-51	165.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,1S6Y2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
k59_149763_1	387093.SUN_1729	3.99e-74	224.0	COG1943@1|root,COG1943@2|Bacteria,1RF1K@1224|Proteobacteria,42VRT@68525|delta/epsilon subdivisions,2YQZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COGs COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_129828_1	526222.Desal_0418	3.25e-34	124.0	COG3516@1|root,COG3516@2|Bacteria,1RA8Z@1224|Proteobacteria,43BGJ@68525|delta/epsilon subdivisions,2X6UU@28221|Deltaproteobacteria,2MBC5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
k59_123077_1	1165841.SULAR_10424	1.66e-84	260.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_102804_1	765912.Thimo_2536	1.08e-96	300.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_109517_1	555779.Dthio_PD2605	2.99e-95	301.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_211310_1	1168034.FH5T_10180	5.46e-110	340.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,2FMFA@200643|Bacteroidia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_123079_1	985054.JQEZ01000004_gene803	2.31e-88	269.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,4NCIX@97050|Ruegeria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve,rve_3
k59_116408_2	395493.BegalDRAFT_2336	7.93e-33	128.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1QP7Y@1224|Proteobacteria,1RR12@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_23
k59_62107_1	756067.MicvaDRAFT_2177	2.75e-35	130.0	COG0784@1|root,COG2114@1|root,COG0784@2|Bacteria,COG2114@2|Bacteria,1G7N3@1117|Cyanobacteria,1HH4D@1150|Oscillatoriales	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_190980_1	189425.PGRAT_28775	7.06e-11	67.8	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1V96A@1239|Firmicutes,4HA3A@91061|Bacilli,26S7J@186822|Paenibacillaceae	91061|Bacilli	KT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GerE,Pkinase
k59_14713_1	1255043.TVNIR_1258	7.04e-49	165.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria,1WWFD@135613|Chromatiales	135613|Chromatiales	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_102809_2	497964.CfE428DRAFT_1385	2.39e-153	449.0	COG3344@1|root,COG3344@2|Bacteria,46SUD@74201|Verrucomicrobia	2|Bacteria	L	Group II intron maturase-specific domain protein	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_28284_1	1121288.AULL01000012_gene286	1.22e-22	88.2	2DNXG@1|root,32ZNF@2|Bacteria,4NV9Z@976|Bacteroidetes,1I563@117743|Flavobacteriia,3ZTY7@59732|Chryseobacterium	976|Bacteroidetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
k59_62109_1	1121403.AUCV01000066_gene4154	1.04e-151	440.0	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2X6QW@28221|Deltaproteobacteria,2MN97@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_21413_1	1408473.JHXO01000008_gene2871	1.04e-118	349.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,2FN52@200643|Bacteroidia	976|Bacteroidetes	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_1130_1	1165841.SULAR_00150	1.29e-116	335.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2YN5M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fumarate	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
k59_82495_1	234267.Acid_6898	3.31e-30	124.0	COG3464@1|root,COG3464@2|Bacteria,3Y89T@57723|Acidobacteria	57723|Acidobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k59_190993_2	402626.Rpic_0481	1.1e-11	62.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,1K4PP@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k59_211342_1	504472.Slin_2494	1.13e-72	229.0	COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_28289_1	2340.JV46_23640	4.57e-164	502.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_109537_1	1283300.ATXB01000001_gene1457	1.43e-78	249.0	COG0294@1|root,COG0294@2|Bacteria,1MWM3@1224|Proteobacteria,1RZMG@1236|Gammaproteobacteria,1XEAQ@135618|Methylococcales	135618|Methylococcales	H	PFAM Dihydropteroate synthase, DHPS	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55332_1	1442598.JABW01000021_gene2067	4.92e-32	123.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2YNEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_204412_1	1123226.KB899288_gene1073	1.07e-34	135.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,26QZ7@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_190996_1	1265313.HRUBRA_00890	1.58e-45	147.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_190996_2	1265313.HRUBRA_00889	1.86e-50	166.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_177239_1	1523503.JPMY01000036_gene1532	2.1e-40	161.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	ko:K20972	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,NIT,Response_reg
k59_185455_1	1121013.P873_03455	3.45e-39	145.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1X32J@135614|Xanthomonadales	135614|Xanthomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_185455_2	1123257.AUFV01000003_gene1268	4.23e-42	144.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S3J8@1236|Gammaproteobacteria,1XC9E@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2238
k59_16158_1	3880.AES87815	0.00035	42.4	2D08W@1|root,2SD7U@2759|Eukaryota,37XFR@33090|Viridiplantae,3GMII@35493|Streptophyta	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface	psbM	-	-	ko:K02714	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbM
k59_104298_1	7029.ACYPI073888-PA	2.34e-07	57.8	COG2801@1|root,KOG0017@2759|Eukaryota,39TC6@33154|Opisthokonta,3BHT2@33208|Metazoa,3D2MB@33213|Bilateria	33208|Metazoa	J	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1758,DUF1759,Peptidase_A17,rve
k59_56727_1	1406840.Q763_06990	1.99e-82	258.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1HX65@117743|Flavobacteriia,2NS73@237|Flavobacterium	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_2723_2	1223523.H340_23763	9.43e-25	107.0	COG1376@1|root,COG2304@1|root,COG1376@2|Bacteria,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
k59_117991_1	2340.JV46_04090	4.74e-97	301.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k59_70292_1	399795.CtesDRAFT_PD1403	3.57e-05	43.5	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,2VTYA@28216|Betaproteobacteria,4AEEH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
k59_117999_1	1410666.JHXG01000006_gene1999	8.33e-06	51.2	COG0446@1|root,COG0446@2|Bacteria,4P0D3@976|Bacteroidetes,2G09K@200643|Bacteroidia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_63653_1	2340.JV46_28320	2.54e-25	103.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1J65J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	MucB/RseB C-terminal domain	rseB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
k59_144820_1	998674.ATTE01000001_gene4265	2.34e-60	200.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,4601P@72273|Thiotrichales	72273|Thiotrichales	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_84006_1	1045855.DSC_12515	1.22e-15	78.2	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,1X3BA@135614|Xanthomonadales	135614|Xanthomonadales	H	Outer membrane receptor proteins mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_206018_1	1121875.KB907548_gene1547	1.13e-82	247.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1I17D@117743|Flavobacteriia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_206018_2	1250232.JQNJ01000001_gene3334	8.95e-11	62.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_158537_1	550540.Fbal_1527	3.22e-68	218.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na H antiporter, MnhB	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
k59_158537_2	1304275.C41B8_05758	4.68e-46	154.0	COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,1S6BB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	NADH-ubiquinone oxidoreductase, chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
k59_36331_1	313603.FB2170_01045	6.51e-81	264.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia	976|Bacteroidetes	E	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_90879_1	2340.JV46_10130	4.76e-147	425.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1J4J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_56756_1	83406.HDN1F_25740	9.01e-40	153.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RWP8@1236|Gammaproteobacteria,1J8D9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Sensor histidine kinase response regulator	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
k59_192423_1	686340.Metal_2853	5.22e-98	294.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XDRY@135618|Methylococcales	135618|Methylococcales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_50275_1	338963.Pcar_0655	1.75e-109	324.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,43S2S@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_97698_1	2340.JV46_16270	3.63e-68	223.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1J4IR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	iYL1228.KPN_04331	ABC1
k59_16197_1	1165841.SULAR_05808	4.04e-125	366.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_124596_1	1232410.KI421418_gene2309	1.4e-121	367.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,43RZS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_185496_1	1122176.KB903554_gene3961	2.77e-83	270.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IR7S@117747|Sphingobacteriia	976|Bacteroidetes	G	Fibronectin type III-like domain	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_50289_1	1540097.A0A0A0YRP0_9CAUD	1.74e-30	120.0	4QEFX@10239|Viruses,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_50289_2	942016.E9NIJ0_9CAUD	1.74e-19	88.2	4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses  no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_206044_1	1165841.SULAR_00270	6.88e-102	303.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2YN18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_138060_1	1121904.ARBP01000010_gene2436	2.65e-29	117.0	COG0457@1|root,COG0642@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,4PI91@976|Bacteroidetes,47UPB@768503|Cytophagia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
k59_118456_1	1049564.TevJSym_bh00150	1.3e-93	290.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1J5FD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	GTP-binding protein TypA	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_57131_2	998674.ATTE01000001_gene347	6.32e-18	82.8	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,460T9@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Surface antigen	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
k59_138364_1	710111.FraQA3DRAFT_6441	7.08e-35	138.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4ERI4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_30291_1	563031.HMPREF0666_01009	3.43e-13	70.1	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,2FKYH@200643|Bacteroidia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_111335_1	1444711.CCJF01000003_gene26	5.51e-34	129.0	COG3566@1|root,COG3566@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2213)	-	-	-	ko:K09960	-	-	-	-	ko00000	-	-	-	DUF2213
k59_3154_1	1165841.SULAR_00900	1.07e-84	261.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42QN4@68525|delta/epsilon subdivisions,2YTQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_70705_1	1121405.dsmv_0691	1.3e-91	283.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_158876_1	314285.KT71_12160	9.41e-26	112.0	COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,1SU06@1236|Gammaproteobacteria,1J4HW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_57142_1	869213.JCM21142_42083	1.04e-19	94.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_9822_2	1165841.SULAR_10679	2.34e-90	266.0	COG5501@1|root,COG5501@2|Bacteria	2|Bacteria	-	-	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
k59_9822_3	1165841.SULAR_10684	1.1e-236	659.0	COG3245@1|root,COG3258@1|root,COG3245@2|Bacteria,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,42WAQ@68525|delta/epsilon subdivisions,2YTG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
k59_9822_4	1165841.SULAR_10689	6.89e-120	353.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42PRR@68525|delta/epsilon subdivisions,2YMYP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	sulfur dehydrogenase subunit	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_104702_1	1515746.HR45_00725	0.000107	48.5	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,1RQJI@1236|Gammaproteobacteria,2Q8ZI@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Translation elongation factor	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_91184_1	472759.Nhal_0211	9.51e-37	129.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1WYAH@135613|Chromatiales	135613|Chromatiales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_91184_2	1049564.TevJSym_bn00120	6.26e-15	72.4	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1JAMF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_16517_1	2340.JV46_02700	2.27e-93	285.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1J7KN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3	ko:K00113,ko:K11473	ko00564,ko00630,ko01100,ko01110,ko01120,ko01130,map00564,map00630,map01100,map01110,map01120,map01130	-	R00475,R00848	RC00029,RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
k59_131764_1	1165841.SULAR_05158	4.82e-121	359.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_111351_1	1297569.MESS2_p90033	1.89e-36	135.0	COG1879@1|root,COG1879@2|Bacteria,1MUJU@1224|Proteobacteria,2U0QP@28211|Alphaproteobacteria,43NWK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_16519_1	997346.HMPREF9374_0035	6.1e-39	139.0	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,27BCW@186824|Thermoactinomycetaceae	91061|Bacilli	K	YsiA-like protein, C-terminal region	fadR	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
k59_111352_1	1165841.SULAR_05998	1.3e-72	224.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2YP4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_111354_1	1168034.FH5T_08420	2.16e-121	362.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FP0Y@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_172475_1	493475.GARC_4224	4.99e-88	269.0	COG1680@1|root,COG1680@2|Bacteria,1MZQ3@1224|Proteobacteria,1RWRY@1236|Gammaproteobacteria,466A7@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
k59_43488_1	313628.LNTAR_20283	5.18e-16	74.7	2A42S@1|root,30SMP@2|Bacteria	2|Bacteria	S	Nickel-containing superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
k59_118488_1	756067.MicvaDRAFT_2896	5.39e-63	220.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H7QZ@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_98112_1	2340.JV46_16820	2.59e-16	76.3	COG0730@1|root,COG0730@2|Bacteria,1QJ79@1224|Proteobacteria,1TH4W@1236|Gammaproteobacteria,1J7SI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_98112_2	1198232.CYCME_0531	1.43e-07	57.0	COG2433@1|root,COG2433@2|Bacteria,1R1QS@1224|Proteobacteria,1T58I@1236|Gammaproteobacteria,463VZ@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_3179_1	1279017.AQYJ01000023_gene3128	7.47e-92	280.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,4647T@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	iPC815.YPO2896,iYL1228.KPN_02862	Aminotran_5
k59_50564_1	981336.F944_02163	1.86e-41	150.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,3NIEG@468|Moraxellaceae	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_50564_2	316407.85676700	8.54e-22	89.4	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,3XMJS@561|Escherichia	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_199726_1	313596.RB2501_15984	1.43e-127	377.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HWJQ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_145415_1	1121875.KB907548_gene1638	2.83e-40	144.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_91200_1	2340.JV46_28810	1.72e-85	262.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1J4VQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	a CheY-like receiver domain and an HD-GYP domain	rpfG	-	-	ko:K07814,ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,HD_5,Response_reg
k59_185921_2	317025.Tcr_0935	7.76e-117	347.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,460RS@72273|Thiotrichales	72273|Thiotrichales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k59_87689_2	1165841.SULAR_03247	1.03e-82	261.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_67518_1	323850.Shew_0050	1.6e-18	87.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S20V@1236|Gammaproteobacteria,2QAVJ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_67518_2	870187.Thini_1892	3.26e-10	60.1	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,461UB@72273|Thiotrichales	72273|Thiotrichales	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_188840_1	1168034.FH5T_07175	1.39e-89	284.0	COG0363@1|root,COG0363@2|Bacteria,4NDUN@976|Bacteroidetes,2FM2W@200643|Bacteroidia	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_155379_1	1165841.SULAR_03048	3.23e-50	174.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_182405_1	714943.Mucpa_1936	1.4e-15	80.9	COG1680@1|root,COG1680@2|Bacteria,4NGX3@976|Bacteroidetes,1ISWT@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_60674_1	314278.NB231_12259	1.81e-153	464.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_6559_1	396588.Tgr7_3068	9.89e-47	159.0	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,1S4C9@1236|Gammaproteobacteria,1X2AK@135613|Chromatiales	135613|Chromatiales	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_216185_1	1165841.SULAR_08192	8.55e-114	328.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2YNX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_216185_2	1165841.SULAR_08197	7.51e-10	58.5	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_6561_1	1121004.ATVC01000040_gene2384	4.49e-51	184.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,2KU4C@206351|Neisseriales	206351|Neisseriales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_67524_1	458817.Shal_0671	1.93e-19	82.4	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,2QCIH@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k59_67524_2	2340.JV46_22130	7.06e-13	65.5	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1J72N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	fxsA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
k59_47052_1	1121904.ARBP01000012_gene1244	1.69e-27	112.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114266_1	1349767.GJA_2793	2.45e-15	76.6	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,472UR@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_135132_1	765912.Thimo_0696	9.89e-95	305.0	COG0474@1|root,COG0474@2|Bacteria,1R5CD@1224|Proteobacteria,1S0AA@1236|Gammaproteobacteria,1WXVQ@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_13067_1	1165841.SULAR_03098	4.2e-130	387.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_128219_1	1353531.AZNX01000037_gene3804	8.17e-73	236.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_148784_1	438753.AZC_3253	8.12e-49	162.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,3F1SC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_148784_2	1430440.MGMSRv2_0014	1.61e-32	119.0	COG3415@1|root,COG3415@2|Bacteria,1NEVE@1224|Proteobacteria	1224|Proteobacteria	L	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_Tnp_IS630
k59_108288_1	195105.CN97_09805	3.44e-11	67.4	COG1266@1|root,COG1266@2|Bacteria,1RFHC@1224|Proteobacteria,2U7KR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
k59_155386_2	314275.MADE_1014600	1.29e-130	385.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
k59_148787_1	314278.NB231_11604	3.58e-78	247.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales	135613|Chromatiales	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_53710_1	1165841.SULAR_06588	1.97e-45	159.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YMGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_53710_2	1165841.SULAR_06583	1.26e-09	57.4	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_202860_1	396588.Tgr7_1308	5.39e-124	360.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,1WXY5@135613|Chromatiales	135613|Chromatiales	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_67530_1	1469245.JFBG01000027_gene1503	2.65e-62	210.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1X2HJ@135613|Chromatiales	135613|Chromatiales	I	acyl-CoA dehydrogenase	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N,AcylCoA_dehyd_C
k59_101165_2	457396.CSBG_01885	3.9e-14	77.8	COG0542@1|root,COG0542@2|Bacteria,1UJ1Z@1239|Firmicutes,24AIQ@186801|Clostridia,36GMD@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_13072_1	2340.JV46_23200	3.2e-48	155.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1J7C4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	bigR	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_13072_2	1442599.JAAN01000004_gene1074	5.03e-33	120.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1X737@135614|Xanthomonadales	135614|Xanthomonadales	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_13072_3	1236541.BALL01000016_gene2249	1.01e-49	163.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,2QAF8@267890|Shewanellaceae	1236|Gammaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_27032_2	2340.JV46_22190	3.18e-33	117.0	COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1J6Y6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	YcgL domain-containing protein	ycgL	-	-	ko:K09902	-	-	-	-	ko00000	-	-	-	YcgL
k59_81326_1	1165841.SULAR_08854	1.6e-105	311.0	COG2204@1|root,COG2204@2|Bacteria,1QUIV@1224|Proteobacteria,42M4N@68525|delta/epsilon subdivisions,2YMIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_210097_1	4081.Solyc00g020040.1.1	1.43e-105	307.0	2C63N@1|root,2QT9Q@2759|Eukaryota,37P22@33090|Viridiplantae,3GH9T@35493|Streptophyta	35493|Streptophyta	-	-	ccmB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	-	-	-	-	-	-	-	-	-	-
k59_162559_1	2340.JV46_25070	1.19e-82	262.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1J4NF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_196413_1	1127673.GLIP_0967	1.93e-57	192.0	COG1680@1|root,COG1680@2|Bacteria,1RIU7@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_142211_1	1165841.SULAR_04808	9.94e-06	47.8	2ENG1@1|root,33G3G@2|Bacteria,1NPIZ@1224|Proteobacteria,42ZV2@68525|delta/epsilon subdivisions,2YRT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142211_2	387093.SUN_1568	5.94e-35	122.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_114593_1	1165841.SULAR_02508	3.38e-83	250.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42QT6@68525|delta/epsilon subdivisions,2YR4C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_101635_1	1165841.SULAR_03657	3.34e-88	281.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_27046_1	463191.SSEG_09996	4.38e-49	159.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_114601_1	393595.ABO_0294	4.72e-51	176.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1XH4R@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_101639_1	550540.Fbal_1295	2.62e-17	87.4	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
k59_196428_1	929556.Solca_3290	7.45e-38	146.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1IR3G@117747|Sphingobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_40262_1	203122.Sde_2736	5.97e-55	174.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,4674B@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_40262_2	2340.JV46_09920	1.65e-49	163.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1J6UK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k59_101647_1	314285.KT71_04100	1.85e-90	277.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1J4KI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	iJN746.PP_5046	Gln-synt_C,Gln-synt_N
k59_142238_1	1122223.KB890697_gene1222	2.29e-11	69.3	COG0330@1|root,COG0330@2|Bacteria,1WJDX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_114616_1	765912.Thimo_1892	2.64e-05	47.8	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_114616_2	1122194.AUHU01000005_gene899	1.23e-07	55.5	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,4689I@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	rodZ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k59_162588_1	391615.ABSJ01000054_gene1432	2.74e-44	155.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1J5JV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Aminotransferase class I and II	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_176206_1	1165841.SULAR_05708	1.88e-92	277.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2YMRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_176206_2	1165841.SULAR_05703	2.38e-40	144.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_176210_2	395493.BegalDRAFT_2007	3.64e-21	92.4	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,1RUDN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_27070_1	1239962.C943_00059	1.95e-30	125.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47N98@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
k59_101660_1	1123228.AUIH01000006_gene2229	3.1e-103	308.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1XIBX@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_101661_1	631362.Thi970DRAFT_02149	1.17e-24	95.5	COG0298@1|root,COG0298@2|Bacteria,1QKV6@1224|Proteobacteria,1SE6V@1236|Gammaproteobacteria,1WZDC@135613|Chromatiales	135613|Chromatiales	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_196450_1	1165841.SULAR_02583	8.6e-77	243.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_40279_2	83406.HDN1F_01990	2.73e-25	98.6	COG3436@1|root,COG3436@2|Bacteria,1N638@1224|Proteobacteria,1SFHC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
k59_40279_3	1535422.ND16A_0183	1.54e-158	469.0	COG3316@1|root,COG3316@2|Bacteria	1535422.ND16A_0183|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74075_1	1173027.Mic7113_3416	1.56e-58	204.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_155840_1	1165841.SULAR_10089	2.23e-173	496.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_40288_1	869213.JCM21142_41627	2.32e-73	235.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_162626_1	1205680.CAKO01000007_gene4444	6.46e-06	51.2	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2UBSM@28211|Alphaproteobacteria,2JYSD@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40305_1	563040.Saut_1116	3.22e-06	48.1	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_196492_1	911045.PSE_3739	1.95e-47	168.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,2TRI4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_131603_2	1415778.JQMM01000001_gene1483	2.61e-17	78.6	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,1J647@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_2989_2	1247963.JPHU01000005_gene255	7.57e-08	56.6	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_165346_1	1165841.SULAR_00415	3.36e-105	309.0	COG1651@1|root,COG1651@2|Bacteria,1RFRJ@1224|Proteobacteria,42SPD@68525|delta/epsilon subdivisions,2YP88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_124854_2	1134474.O59_000070	2.44e-41	144.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07506,ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k59_43367_1	1128421.JAGA01000003_gene3441	1.1e-68	220.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
k59_36505_1	2340.JV46_08040	2.34e-60	191.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1J5WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0678 Peroxiredoxin	VY92_02980	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Glutaredoxin,Redoxin
k59_111180_1	1089548.KI783301_gene2730	2.28e-40	149.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,3WFT1@539002|Bacillales incertae sedis	91061|Bacilli	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_30116_1	1137799.GZ78_16340	6.58e-93	282.0	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,1RQB4@1236|Gammaproteobacteria,1XIYY@135619|Oceanospirillales	135619|Oceanospirillales	E	PFAM peptidase M14 carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_63867_1	411476.BACOVA_04052	1.12e-34	135.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,2FKYA@200643|Bacteroidia,4AKTY@815|Bacteroidaceae	976|Bacteroidetes	I	pectin acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DUF1460,Peptidase_S9
k59_104542_1	1049564.TevJSym_ak00090	1.77e-111	331.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1J68F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_97980_1	1165841.SULAR_09039	3.12e-113	332.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_63868_1	1165841.SULAR_01578	9.11e-103	301.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2YNTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_43371_1	686340.Metal_0769	5.26e-53	177.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1XE1X@135618|Methylococcales	135618|Methylococcales	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_178837_1	1165841.SULAR_06908	1.48e-120	349.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2YN6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_84294_2	1133850.SHJG_5895	3.47e-16	79.7	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
k59_145205_1	1165841.SULAR_00925	1.23e-68	209.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42U5E@68525|delta/epsilon subdivisions,2YPTW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k59_77442_1	572480.Arnit_1227	1.93e-74	234.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2YNCJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter permease	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_30123_1	1304878.AUGD01000001_gene393	2.02e-59	199.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3JS73@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_131623_1	1168034.FH5T_09310	6.16e-129	375.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,2FS6N@200643|Bacteroidia	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
k59_63875_1	1165841.SULAR_05448	7.76e-79	253.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_145212_1	1168034.FH5T_04925	6.01e-11	60.8	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	fpr	GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004324,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0016043,GO:0016052,GO:0016226,GO:0016491,GO:0016730,GO:0016731,GO:0019318,GO:0019320,GO:0022607,GO:0031163,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901700	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	iECIAI39_1322.ECIAI39_3072,iEcSMS35_1347.EcSMS35_4364,iYL1228.KPN_04002	FAD_binding_6,NAD_binding_1
k59_84683_1	6500.XP_005102740.1	2.56e-90	295.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CZSS@33213|Bilateria	33208|Metazoa	G	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve,zf-H2C2
k59_172645_1	1122201.AUAZ01000044_gene1315	2.79e-98	295.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,4655F@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_77694_1	1168034.FH5T_16615	3.37e-91	286.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,2FNTX@200643|Bacteroidia	976|Bacteroidetes	P	TrkA C-terminal domain protein	kefC	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_145572_1	1168034.FH5T_08775	7.23e-114	335.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_30448_1	519989.ECTPHS_04124	8.27e-86	271.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1WXBU@135613|Chromatiales	135613|Chromatiales	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
k59_50677_1	387093.SUN_0193	7.52e-103	319.0	COG4166@1|root,COG4166@2|Bacteria,1Q4KZ@1224|Proteobacteria,43A0X@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_104911_2	941639.BCO26_0951	1.09e-47	164.0	COG1028@1|root,COG1028@2|Bacteria,1TPDB@1239|Firmicutes,4HAKR@91061|Bacilli,1ZDEP@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
k59_145575_1	1121012.AUKX01000001_gene1295	2.16e-17	82.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia,23GB0@178469|Arenibacter	976|Bacteroidetes	M	Surface antigen	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_145575_2	1004149.AFOE01000020_gene3091	1.07e-66	209.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_36804_1	2340.JV46_27860	1.32e-75	240.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1JBHG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	ArsB,CitMHS
k59_104912_1	572477.Alvin_3113	8.29e-136	410.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_91370_3	948071.S4S2D9_9CAUD	8.25e-134	402.0	4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses  no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae	10744|Podoviridae	S	ribonucleoside-triphosphate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3352_1	65393.PCC7424_2981	8.48e-53	192.0	COG3568@1|root,COG3568@2|Bacteria,1G09C@1117|Cyanobacteria,3KJ78@43988|Cyanothece	1117|Cyanobacteria	S	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_118668_1	765913.ThidrDRAFT_3507	2.73e-82	270.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_30454_2	1165841.SULAR_04577	8.21e-50	163.0	COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,43BAA@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	paraquat-inducible protein A	pqiA2	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_138627_2	880073.Calab_0209	9.37e-19	89.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	-	-	1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13	ko:K00123,ko:K00317,ko:K00528,ko:K09835	ko00630,ko00680,ko00906,ko01100,ko01110,ko01120,ko01200,map00630,map00680,map00906,map01100,map01110,map01120,map01200	M00097	R00519,R01588,R02511,R07512,R10159	RC00185,RC00556,RC00557,RC00732,RC01960,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4_20,NAD_binding_8,Oxidored_FMN,Pyr_redox_2
k59_193005_1	313596.RB2501_00781	3.68e-164	464.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1HXE2@117743|Flavobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_179078_1	713586.KB900536_gene3055	1.13e-88	275.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_165745_1	401526.TcarDRAFT_1697	2.95e-24	99.8	COG0613@1|root,COG0613@2|Bacteria,1V3ZK@1239|Firmicutes,4H203@909932|Negativicutes	909932|Negativicutes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
k59_165745_2	1168034.FH5T_03095	3.48e-32	114.0	COG4109@1|root,COG4109@2|Bacteria,4NTA0@976|Bacteroidetes,2FTZ6@200643|Bacteroidia	976|Bacteroidetes	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
k59_213308_1	1442599.JAAN01000033_gene1670	2.64e-34	131.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1X3C8@135614|Xanthomonadales	135614|Xanthomonadales	M	tonb protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_213308_2	765911.Thivi_3311	2.02e-32	118.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1WX8T@135613|Chromatiales	135613|Chromatiales	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_152353_1	998674.ATTE01000001_gene2583	1.92e-39	141.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,45ZXT@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
k59_152353_2	1123401.JHYQ01000002_gene2576	7.48e-19	82.8	COG3193@1|root,COG3193@2|Bacteria,1RJ3X@1224|Proteobacteria,1S8FV@1236|Gammaproteobacteria,462NR@72273|Thiotrichales	72273|Thiotrichales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k59_36823_1	3983.cassava4.1_010787m	4.32e-18	87.8	COG1515@1|root,KOG4417@2759|Eukaryota,37NHV@33090|Viridiplantae,3GG9X@35493|Streptophyta,4JD5S@91835|fabids	35493|Streptophyta	L	endonuclease	-	GO:0000287,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004536,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016888,GO:0016891,GO:0016893,GO:0031974,GO:0031981,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901363	-	ko:K21813	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
k59_23465_2	102125.Xen7305DRAFT_00053650	5.65e-53	180.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1G1TK@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_159064_2	2340.JV46_06190	8.04e-52	164.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1J7AX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887	-	-	-	-	-	-	-	-	-	-	Iron_traffic
k59_64152_1	3712.Bo5g098620.1	6.39e-07	49.3	2E7CP@1|root,2R1P8@2759|Eukaryota,383D7@33090|Viridiplantae,3GWXB@35493|Streptophyta,3I19M@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_64152_2	4081.Solyc01g007650.2.1	7.05e-41	135.0	2CQT8@1|root,2R5Q2@2759|Eukaryota,386GT@33090|Viridiplantae,3GUDY@35493|Streptophyta,44UFM@71274|asterids	35493|Streptophyta	S	Chloroplast protein precursor Ycf15 putative	-	-	-	-	-	-	-	-	-	-	-	-	Ycf15
k59_64152_3	4081.Solyc01g007640.2.1	0.0	2508.0	2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids	35493|Streptophyta	C	Plant protein of unknown function (DUF825)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA,DUF825
k59_57336_2	590409.Dd586_2073	8.71e-21	92.8	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,2JDTZ@204037|Dickeya	1236|Gammaproteobacteria	S	Haloacid dehalogenase domain protein hydrolase type 3	yedP	-	2.7.1.31,3.1.3.70	ko:K07026,ko:K15918	ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200	M00532	R01514,R05790	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3,S6PP
k59_118701_1	1165841.SULAR_07675	3.67e-91	281.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2YTAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_118701_2	1165841.SULAR_07670	9.31e-20	87.8	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,42ZSN@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_165759_1	686340.Metal_0903	3.73e-06	50.4	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1XDVU@135618|Methylococcales	135618|Methylococcales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_145591_1	1198452.Jab_1c08880	1.25e-15	79.3	COG0457@1|root,COG2199@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1R2E9@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_12
k59_145591_2	953739.SVEN_1612	3.47e-14	73.2	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
k59_186164_1	349521.HCH_03681	6.78e-40	137.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1S8VE@1236|Gammaproteobacteria,1XKNR@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	cadR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
k59_165760_1	1215114.BBIU01000039_gene3865	3.04e-67	208.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_30476_1	1123355.JHYO01000012_gene725	2.17e-55	183.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,370AV@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	natD	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_9981_1	1007105.PT7_1017	6.76e-08	52.8	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,3T2C5@506|Alcaligenaceae	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_9981_2	2340.JV46_14520	1.27e-46	163.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1J4DX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_186165_2	994479.GL877878_gene2063	2.18e-09	63.2	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4E1BI@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Ketoacyl-synt_C,Methyltransf_12,Methyltransf_23,Nitroreductase,PP-binding,Thioesterase,ketoacyl-synt
k59_155530_1	266265.Bxe_A3739	1.06e-49	168.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,2VMVE@28216|Betaproteobacteria,1K5SK@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_155530_2	1331060.RLDS_25255	3.61e-23	100.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,2TVA2@28211|Alphaproteobacteria,2KCS3@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_203074_1	1049564.TevJSym_ac00080	6.47e-147	417.0	COG1143@1|root,COG1143@2|Bacteria,1QWGE@1224|Proteobacteria,1SKS7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
k59_203074_2	1049564.TevJSym_ac00070	1.86e-103	308.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,1SJST@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
k59_189084_1	101162.XP_007693440.1	1.47e-08	61.2	COG0531@1|root,KOG1287@2759|Eukaryota,39YGD@33154|Opisthokonta,3P1KM@4751|Fungi,3QQZE@4890|Ascomycota,200B2@147541|Dothideomycetes,4KBR9@92860|Pleosporales	4751|Fungi	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_87873_1	768671.ThimaDRAFT_2367	7.26e-62	201.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales	135613|Chromatiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_67742_1	313596.RB2501_02035	1.76e-10	68.2	COG1361@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,4PKI1@976|Bacteroidetes,1IJ9R@117743|Flavobacteriia	976|Bacteroidetes	M	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CUB,Calx-beta,DUF11,SdrD_B
k59_94714_1	565045.NOR51B_2798	2.6e-16	76.6	2DBXS@1|root,2ZBR1@2|Bacteria,1RBUD@1224|Proteobacteria,1S1ZK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94714_2	34007.IT40_24760	2.99e-21	89.0	COG2044@1|root,COG2044@2|Bacteria,1RIFN@1224|Proteobacteria,2UBMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_81071_1	1165841.SULAR_04117	7.62e-138	406.0	COG1196@1|root,COG1196@2|Bacteria,1QUJ1@1224|Proteobacteria,42P7I@68525|delta/epsilon subdivisions,2YMKS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
k59_81071_2	1165841.SULAR_04112	1.07e-23	90.5	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2YPTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_26826_1	4565.EPlTAEP00000010095	4.93e-13	72.4	2EVD3@1|root,2SXD4@2759|Eukaryota,389WW@33090|Viridiplantae,3GYZ4@35493|Streptophyta,3M92P@4447|Liliopsida,3ISTD@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73866_1	85643.Tmz1t_3866	3.03e-45	156.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2VSM1@28216|Betaproteobacteria,2M008@206389|Rhodocyclales	1224|Proteobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_216448_1	1165841.SULAR_00510	1.94e-100	304.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2YMFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_169312_1	118163.Ple7327_4324	5.62e-43	160.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GD97@1117|Cyanobacteria,3VI2Q@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,PAS_9,Pkinase,Response_reg
k59_60877_1	1479237.JMLY01000001_gene2710	2.35e-40	149.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4650C@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG0348 Polyferredoxin	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_101349_1	2340.JV46_27230	1.65e-134	392.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1J4Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_176580_1	289376.THEYE_A0114	6.44e-95	286.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_41054_1	272560.BPSS0524	1.06e-40	157.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria,1K160@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Rhs element Vgr	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
k59_88522_1	102232.GLO73106DRAFT_00021500	8.12e-85	266.0	COG1004@1|root,COG1004@2|Bacteria,1GBDR@1117|Cyanobacteria	1117|Cyanobacteria	M	UDP binding domain	-	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_183330_1	439235.Dalk_5256	2.46e-117	348.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MNIW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_74880_1	1165841.SULAR_08030	4.67e-24	95.1	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2YMFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_74880_2	1165841.SULAR_08035	2.04e-65	199.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2YPG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_149476_1	765914.ThisiDRAFT_0267	8.66e-22	96.3	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,1RSFG@1236|Gammaproteobacteria,1WW9R@135613|Chromatiales	135613|Chromatiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k59_149476_2	1120985.AUMI01000021_gene2777	0.000277	43.5	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4H8VR@909932|Negativicutes	909932|Negativicutes	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_176586_1	1165841.SULAR_09554	2.33e-93	285.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_68202_1	1027371.GOALK_067_01000	3.39e-36	132.0	COG0745@1|root,COG0745@2|Bacteria,2GP1I@201174|Actinobacteria,4GBJA@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	vicR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_41063_1	1232683.ADIMK_3486	1.96e-07	54.7	COG0664@1|root,COG0664@2|Bacteria,1QBEY@1224|Proteobacteria,1SJDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_41063_2	1396418.BATQ01000133_gene4051	1.04e-05	46.2	COG0664@1|root,COG0664@2|Bacteria,46X6S@74201|Verrucomicrobia,2IURE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_169745_1	102107.XP_008223735.1	0.0	1065.0	COG1007@1|root,KOG4668@2759|Eukaryota,37P90@33090|Viridiplantae,3GBJ3@35493|Streptophyta,4JRH7@91835|fabids	35493|Streptophyta	C	A subunit of NADH dehydrogenase	ndhF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_169745_2	29760.VIT_00s0246g00170.t01	2.95e-166	473.0	COG0755@1|root,2QU0T@2759|Eukaryota,37NBU@33090|Viridiplantae,3GH1G@35493|Streptophyta	35493|Streptophyta	O	Cytochrome c biogenesis protein CcsA	ccsA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0008152,GO:0009536,GO:0015886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:1901678	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_169745_3	3827.XP_004516946.1	5.33e-299	827.0	COG1008@1|root,KOG4845@2759|Eukaryota,37QQT@33090|Viridiplantae,3G7MJ@35493|Streptophyta,4JSGR@91835|fabids	35493|Streptophyta	C	NAD(P)H-quinone oxidoreductase chain 4	ndhD	-	1.6.5.3	ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M
k59_169745_4	3075.A0A023HHU3	2.36e-36	124.0	COG1145@1|root,2S26M@2759|Eukaryota,37VAY@33090|Viridiplantae,34IB8@3041|Chlorophyta	3041|Chlorophyta	C	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn	psaC	-	-	ko:K02691	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Fer4
k59_169745_5	4155.Migut.D01252.1.p	5.47e-60	185.0	KOG4669@1|root,KOG4669@2759|Eukaryota,37V63@33090|Viridiplantae,3GJK7@35493|Streptophyta,44TJB@71274|asterids	35493|Streptophyta	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008137,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042180,GO:0042181,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050136,GO:0051186,GO:0051188,GO:0055035,GO:0055114,GO:0071704,GO:0098796,GO:1901576,GO:1901661,GO:1901663,GO:1902494	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
k59_169745_6	4155.Migut.D01251.1.p	9.68e-108	312.0	COG0839@1|root,2QQHR@2759|Eukaryota,37N23@33090|Viridiplantae,3GCEY@35493|Streptophyta,44PRZ@71274|asterids	35493|Streptophyta	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	ndhG	GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0044237	1.6.5.3	ko:K05578	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q3
k59_169745_7	4155.Migut.D01250.1.p	5.88e-102	296.0	COG1143@1|root,KOG3256@2759|Eukaryota,37YQF@33090|Viridiplantae,3GCUY@35493|Streptophyta,44RDM@71274|asterids	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhI	GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0055114	1.6.5.3	ko:K05580	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
k59_169745_8	4155.Migut.D01248.1.p	1.62e-102	310.0	COG0649@1|root,COG1005@1|root,KOG2870@2759|Eukaryota,KOG4770@2759|Eukaryota,383XN@33090|Viridiplantae,3GWT5@35493|Streptophyta,44QAB@71274|asterids	35493|Streptophyta	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K03878,ko:K05572	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADHdh
k59_169745_9	59689.scaffold_900034.1	3.15e-276	756.0	COG0649@1|root,KOG2870@2759|Eukaryota,37KKG@33090|Viridiplantae,3GDNP@35493|Streptophyta,3I15P@3699|Brassicales	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhH	GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0015979,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0019866,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0055035,GO:0055114,GO:0070469,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05572,ko:K05579	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_49kDa,NADHdh
k59_169745_10	59689.Al_scaffold_0009_187	5.67e-34	119.0	COG0184@1|root,KOG2815@2759|Eukaryota,37W6V@33090|Viridiplantae,3GKIP@35493|Streptophyta	35493|Streptophyta	J	30S ribosomal protein S15	rps15	GO:0000312,GO:0000313,GO:0000314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0009507,GO:0009532,GO:0009536,GO:0009547,GO:0009570,GO:0015935,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_169745_11	4155.Migut.D01247.1.p	5.61e-266	747.0	28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GWYD@35493|Streptophyta,44U2H@71274|asterids	35493|Streptophyta	U	Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_122376_1	666685.R2APBS1_0004	7.4e-90	285.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1X51M@135614|Xanthomonadales	135614|Xanthomonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_81715_1	1163617.SCD_n02290	1.21e-60	215.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
k59_115606_1	330214.NIDE0901	1.75e-110	340.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
k59_102123_1	313628.LNTAR_17398	1.38e-100	309.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_190229_1	1280947.HY30_17055	3.01e-82	247.0	COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,2UDER@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	manC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_135885_1	998674.ATTE01000001_gene4108	1.98e-104	307.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,461WB@72273|Thiotrichales	72273|Thiotrichales	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_13958_1	690585.JNNU01000002_gene5149	2.56e-22	89.7	COG3620@1|root,COG3620@2|Bacteria,1N84U@1224|Proteobacteria,2V2K4@28211|Alphaproteobacteria,4BGP2@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_88539_1	1165841.SULAR_10424	4.16e-140	407.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_74896_1	29730.Gorai.001G166300.1	5.6e-36	134.0	COG1008@1|root,KOG4845@2759|Eukaryota,37KP8@33090|Viridiplantae,3GEAS@35493|Streptophyta	35493|Streptophyta	C	Proton-conducting membrane transporter	nad4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.6.5.3	ko:K03881	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_102126_2	238854.Q5GQM6_BPSYP	1.54e-83	271.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae	10662|Myoviridae	S	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_88540_2	944435.AXAJ01000001_gene58	3.99e-20	93.6	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,2VJKI@28216|Betaproteobacteria,1K0RW@119060|Burkholderiaceae	28216|Betaproteobacteria	P	phosphonate ABC transporter	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_68219_1	880526.KE386488_gene1177	1.39e-31	117.0	COG3787@1|root,COG3787@2|Bacteria,4NSSF@976|Bacteroidetes,2FYET@200643|Bacteroidia,22UJ9@171550|Rikenellaceae	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_149495_2	1589733.A0A0C5AIV3_9CAUD	1.25e-41	142.0	4QBKQ@10239|Viruses,4QQM7@28883|Caudovirales,4QIAS@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage translational regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61423_1	1123057.P872_11705	2.81e-56	190.0	2DB8Y@1|root,2Z7TF@2|Bacteria,4NIJ2@976|Bacteroidetes,47MSP@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
k59_135891_2	411154.GFO_2921	3.65e-40	144.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_129092_1	1089553.Tph_c16380	1.32e-21	96.7	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,42EY5@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Conserved carboxylase region	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_129093_1	314282.PCNPT3_05870	2.59e-24	100.0	COG0332@1|root,COG0332@2|Bacteria,1P9I2@1224|Proteobacteria,1RP3B@1236|Gammaproteobacteria,2QHTV@267894|Psychromonadaceae	1236|Gammaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
k59_129093_2	381666.H16_A1655	1.75e-26	108.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,2VMNU@28216|Betaproteobacteria,1KFJK@119060|Burkholderiaceae	28216|Betaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_129094_1	1276920.ADIAG_00033	4.12e-24	103.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,1W8II@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_27545_1	748247.AZKH_3147	1.46e-78	244.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VJM9@28216|Betaproteobacteria,2KYGS@206389|Rhodocyclales	206389|Rhodocyclales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15552	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
k59_54622_1	1249627.D779_3736	1.73e-39	155.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WXP6@135613|Chromatiales	135613|Chromatiales	O	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_7138_1	1168034.FH5T_06775	1.88e-55	177.0	COG1917@1|root,COG1917@2|Bacteria,4NMER@976|Bacteroidetes,2G0DI@200643|Bacteroidia	976|Bacteroidetes	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
k59_7138_2	1408473.JHXO01000001_gene2386	1.12e-24	102.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,2FMTR@200643|Bacteroidia	976|Bacteroidetes	IQ	Psort location Cytoplasmic, score 9.97	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_61429_1	1165841.SULAR_06168	5.07e-43	144.0	COG2406@1|root,COG2406@2|Bacteria,1RE25@1224|Proteobacteria,42PJ1@68525|delta/epsilon subdivisions,2YMUJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ferritin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_68226_1	1121875.KB907547_gene3273	3.78e-72	240.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_81739_1	269799.Gmet_3277	3.02e-38	142.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,43S0X@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k59_20798_3	313624.NSP_14380	5.93e-27	100.0	COG2886@1|root,COG2886@2|Bacteria,1G8FV@1117|Cyanobacteria,1HPCD@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
k59_135904_1	1140.Synpcc7942_1233	1.31e-11	65.5	COG1226@1|root,32Y28@2|Bacteria,1G7VB@1117|Cyanobacteria,1H1NC@1129|Synechococcus	1117|Cyanobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
k59_135904_2	1122132.AQYH01000007_gene2179	8.26e-25	100.0	2DS4T@1|root,32USD@2|Bacteria,1RIFI@1224|Proteobacteria,2UBWM@28211|Alphaproteobacteria,4B97C@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135904_3	990285.RGCCGE502_16145	3.93e-42	150.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2TTW3@28211|Alphaproteobacteria,4BC3Z@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	Biotin-lipoyl like	yiaV	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
k59_169766_1	985665.HPL003_07770	9.2e-61	193.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,26SCN@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
k59_61438_1	765912.Thimo_2944	2.28e-130	377.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales	135613|Chromatiales	K	LysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_183357_1	999141.GME_17422	2.49e-151	451.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria,1XHBF@135619|Oceanospirillales	135619|Oceanospirillales	LV	RNA-directed DNA polymerase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k59_54630_1	395493.BegalDRAFT_1229	3.04e-123	365.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,45ZST@72273|Thiotrichales	72273|Thiotrichales	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_10319_1	264402.Cagra.5120s0021.1.p	1.13e-75	237.0	COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,3GF4E@35493|Streptophyta	35493|Streptophyta	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis	cob	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_125588_1	395493.BegalDRAFT_0251	1.07e-200	572.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,45ZSH@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_64537_1	1168034.FH5T_10340	1.72e-112	329.0	COG3177@1|root,COG3177@2|Bacteria,4NHPW@976|Bacteroidetes,2FQXS@200643|Bacteroidia	976|Bacteroidetes	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
k59_50992_1	765913.ThidrDRAFT_3373	1.22e-50	177.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1WXKA@135613|Chromatiales	135613|Chromatiales	G	PFAM Alpha amylase, catalytic	-	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_78127_3	314275.MADE_000001022545	6.69e-25	103.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,465QU@72275|Alteromonadaceae	1236|Gammaproteobacteria	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Mrr_cat,SNF2_N,SWIM
k59_139492_1	3880.AES69832	4.92e-87	273.0	28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,4JV38@91835|fabids	35493|Streptophyta	J	Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns	matK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K20000	-	-	-	-	ko00000,ko03016	-	-	-	Intron_maturas2,MatK_N
k59_85464_1	501479.ACNW01000112_gene3996	3.24e-25	105.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSP5@28211|Alphaproteobacteria	1224|Proteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_186884_1	313596.RB2501_10392	1.08e-100	308.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia	976|Bacteroidetes	T	gtp-binding protein typa	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_119445_1	1165841.SULAR_10074	1.1e-129	380.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,42M7N@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.10.3.10,1.9.3.1	ko:K02275,ko:K02297	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX2,COX2_TM,COX_ARM,Cytochrom_C,Cytochrome_CBB3
k59_64902_1	981384.AEYW01000001_gene1561	0.000752	48.9	COG1404@1|root,COG2374@1|root,COG3391@1|root,COG1404@2|Bacteria,COG2374@2|Bacteria,COG3391@2|Bacteria,1QU1I@1224|Proteobacteria,2TYS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_64902_2	1111732.AZOD01000006_gene96	2.8e-40	140.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1X61I@135614|Xanthomonadales	135614|Xanthomonadales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MafB19-deam,dCMP_cyt_deam_1
k59_179985_1	411154.GFO_1587	1.26e-147	424.0	COG3328@1|root,COG3328@2|Bacteria,4NFQS@976|Bacteroidetes,1HZYN@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_200575_1	519989.ECTPHS_02219	1.18e-37	138.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_92201_1	1168034.FH5T_08780	1.04e-31	119.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,2FPCQ@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_92201_2	1168034.FH5T_08790	1.08e-40	145.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,2FNYP@200643|Bacteroidia	976|Bacteroidetes	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_159906_1	1165841.SULAR_07560	9.08e-80	254.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_159906_2	1165841.SULAR_07565	4.03e-57	178.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2YPSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iIT341.HP1270	Oxidored_q2
k59_159906_3	1165841.SULAR_07570	1.37e-62	195.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2YP9Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_132936_1	749222.Nitsa_0937	2.09e-51	169.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_78496_1	395493.BegalDRAFT_2557	2.74e-70	241.0	COG0784@1|root,COG2199@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
k59_193846_1	2340.JV46_05980	7.41e-37	133.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1J4TG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040	CPSase_sm_chain,GATase
k59_193846_2	2340.JV46_05970	5.43e-32	113.0	COG2841@1|root,COG2841@2|Bacteria,1PJVG@1224|Proteobacteria,1TB3F@1236|Gammaproteobacteria,1JBHY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
k59_193846_3	935567.JAES01000003_gene255	3.84e-61	208.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1X3MZ@135614|Xanthomonadales	135614|Xanthomonadales	F	Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_200576_1	391587.KAOT1_06712	4.85e-130	400.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes,1I0F2@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_85479_1	1537917.JU82_01000	6.33e-54	189.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_71664_1	2340.JV46_05280	2e-32	120.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_112185_1	1265505.ATUG01000002_gene1768	4.93e-25	100.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MMZ2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
k59_112185_2	1265505.ATUG01000002_gene1767	7.7e-77	242.0	COG2070@1|root,COG2070@2|Bacteria,1RH4W@1224|Proteobacteria,42T0D@68525|delta/epsilon subdivisions,2WPHF@28221|Deltaproteobacteria,2MN8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_58199_1	351348.Maqu_1487	1.25e-104	318.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,464X8@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	iJN746.PP_2734	CMAS
k59_213941_1	768671.ThimaDRAFT_3603	2.41e-52	170.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,1X266@135613|Chromatiales	135613|Chromatiales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k59_213941_2	456442.Mboo_0803	1.1e-13	72.4	COG1055@1|root,arCOG00238@2157|Archaea,2XVDU@28890|Euryarchaeota,2N961@224756|Methanomicrobia	224756|Methanomicrobia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_31160_1	314230.DSM3645_18186	8.82e-162	466.0	COG5433@1|root,COG5433@2|Bacteria,2J2DN@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_132947_1	1165841.SULAR_06883	2.61e-99	315.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_85487_1	223283.PSPTO_5490	1.54e-19	90.5	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1Z5VN@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	yeaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_159919_1	395493.BegalDRAFT_3132	8.53e-106	313.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,45ZXS@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_180001_1	1042163.BRLA_c039630	1.45e-16	78.6	28HKZ@1|root,2Z7VP@2|Bacteria,1UZIF@1239|Firmicutes,4HCU2@91061|Bacilli,271JZ@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF3050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3050
k59_10659_1	459495.SPLC1_S520210	2.52e-46	170.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_9
k59_159923_1	1168034.FH5T_05935	3.31e-98	297.0	COG0845@1|root,COG0845@2|Bacteria,4NIP7@976|Bacteroidetes,2FQAJ@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_44426_2	631362.Thi970DRAFT_02241	7.92e-08	55.8	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WX0W@135613|Chromatiales	135613|Chromatiales	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_105828_1	1123401.JHYQ01000005_gene247	2.79e-92	281.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,4637B@72273|Thiotrichales	72273|Thiotrichales	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_200590_1	227086.JGI_V11_92730	3.35e-51	179.0	COG0126@1|root,KOG1367@2759|Eukaryota	2759|Eukaryota	G	phosphoglycerate kinase activity	-	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_213953_1	2340.JV46_27850	3.17e-52	170.0	COG0517@1|root,COG0517@2|Bacteria,1NJC6@1224|Proteobacteria,1SV2H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_213953_2	1485544.JQKP01000003_gene282	1.26e-84	265.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,2WFEH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_44429_2	1123024.AUII01000011_gene4420	2.37e-15	75.1	COG3029@1|root,COG3029@2|Bacteria,2IQ2Z@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
k59_44429_3	1036674.A28LD_1090	2.84e-10	60.5	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,2QF76@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	frdB	GO:0000104,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0040011,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0051179,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0051674,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0097588,GO:0098796,GO:0098797,GO:0098803	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0359,iSDY_1059.SDY_4397	Fer2_3,Fer4_8
k59_126020_1	1123319.AUBE01000014_gene5537	1.98e-63	211.0	COG1167@1|root,COG1167@2|Bacteria,2I310@201174|Actinobacteria	201174|Actinobacteria	EK	Pfam Aminotransferase class I and II	-	-	2.6.1.103	ko:K16423	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06626,R06634	RC00006,RC01104	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_105835_1	1173762.S4TT67_9CAUD	1.06e-56	191.0	4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses  no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105835_2	1476391.X5L118_9CAUD	1.58e-18	85.1	4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses  no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae	10744|Podoviridae	S	viral capsid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132969_1	1165841.SULAR_08859	3.14e-83	257.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_105836_1	225117.XP_009335215.1	6.05e-69	235.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae,3GBWZ@35493|Streptophyta,4JT11@91835|fabids	35493|Streptophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve
k59_105836_2	28532.XP_010534024.1	9.95e-14	71.6	COG2801@1|root,KOG0017@2759|Eukaryota,38A0D@33090|Viridiplantae,3GW7H@35493|Streptophyta,3I0KZ@3699|Brassicales	35493|Streptophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146498_1	658187.LDG_7585	2.89e-136	394.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1JDF5@118969|Legionellales	118969|Legionellales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_146498_2	493475.GARC_1293	8.36e-35	121.0	COG2963@1|root,COG2963@2|Bacteria,1N2T5@1224|Proteobacteria,1S6PQ@1236|Gammaproteobacteria,46CXP@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_105840_1	1165841.SULAR_10609	9.93e-82	252.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,42P5E@68525|delta/epsilon subdivisions,2YN01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fad-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_166556_1	3702.ATCG00180.1	5.58e-37	137.0	COG0086@1|root,2QPYA@2759|Eukaryota,37HVM@33090|Viridiplantae,3GFWY@35493|Streptophyta	35493|Streptophyta	K	DNA-directed RNA polymerase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009295,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3
k59_166556_2	4155.Migut.D01417.1.p	1.48e-93	296.0	COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta,44N3V@71274|asterids	35493|Streptophyta	K	RNA polymerase Rpb2, domain 7	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_186924_1	1168034.FH5T_09195	3.21e-86	277.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_180034_1	1168034.FH5T_16755	7.94e-88	276.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_71705_1	317025.Tcr_1646	2.58e-29	114.0	COG2842@1|root,COG2842@2|Bacteria,1R9BD@1224|Proteobacteria,1SCZF@1236|Gammaproteobacteria,462I6@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
k59_7227_1	1165841.SULAR_05923	1.83e-87	272.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2YMQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_115730_1	1349822.NSB1T_09990	6.91e-80	245.0	COG0788@1|root,COG0788@2|Bacteria,4NEGJ@976|Bacteroidetes,2FN3H@200643|Bacteroidia,22WMI@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_41172_1	1165841.SULAR_06018	1.31e-44	158.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_41172_2	1165841.SULAR_06013	3.3e-89	263.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,42ST2@68525|delta/epsilon subdivisions,2YPG7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_210650_1	1142394.PSMK_08620	2.09e-55	193.0	COG0155@1|root,COG0155@2|Bacteria,2IXG2@203682|Planctomycetes	203682|Planctomycetes	C	Sulfite reductase beta subunit (hemoprotein)	-	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_190344_1	1408433.JHXV01000006_gene2733	5.95e-25	100.0	2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,1IERR@117743|Flavobacteriia,2PC5B@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1705
k59_27666_1	2340.JV46_10330	8.74e-57	177.0	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,1J6TU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1244)	IV02_17390	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
k59_27666_2	2340.JV46_10320	7.2e-75	234.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1J6GX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin	ybbN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_176719_1	1165841.SULAR_04587	4.02e-80	249.0	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2YMK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1
k59_183471_1	1168034.FH5T_20495	6.01e-41	149.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,2FPG7@200643|Bacteroidia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_142835_1	1123401.JHYQ01000002_gene2607	1.07e-110	349.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,461RZ@72273|Thiotrichales	72273|Thiotrichales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_156459_1	1336245.JAGO01000003_gene589	1.71e-36	133.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XHDH@135619|Oceanospirillales	135619|Oceanospirillales	F	carbamoyl-phosphate synthetase glutamine chain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_122518_1	1268237.G114_16380	3.22e-16	83.2	2DPBK@1|root,331E1@2|Bacteria,1NCT1@1224|Proteobacteria,1SSKK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_122518_3	926692.AZYG01000040_gene1492	2.73e-30	124.0	COG0535@1|root,COG0535@2|Bacteria,1UMP8@1239|Firmicutes,24BXU@186801|Clostridia,3WABZ@53433|Halanaerobiales	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,Fer4_14,PDZ,PDZ_2,Radical_SAM
k59_75008_2	1123236.KB899383_gene2694	1.34e-24	106.0	COG3405@1|root,COG3405@2|Bacteria,1MW17@1224|Proteobacteria,1RNEU@1236|Gammaproteobacteria,46CUC@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 8	bcsZ	-	3.2.1.4	ko:K01179,ko:K20542	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH8,GH9	-	Glyco_hydro_8
k59_515_1	765914.ThisiDRAFT_0114	2.16e-25	104.0	COG1637@1|root,COG1637@2|Bacteria,1R188@1224|Proteobacteria,1SM3M@1236|Gammaproteobacteria,1X0AN@135613|Chromatiales	135613|Chromatiales	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115738_1	395493.BegalDRAFT_1992	1.07e-31	126.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Type I restriction-modification system methyltransferase subunit	hsdM	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_129207_1	472759.Nhal_0657	1.23e-117	344.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1WWXU@135613|Chromatiales	135613|Chromatiales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_20923_1	1165841.SULAR_10324	5.7e-76	240.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_20923_2	1165841.SULAR_10329	2.34e-79	236.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2YP5I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_108927_1	99598.Cal7507_0774	1.43e-56	191.0	COG2008@1|root,COG2008@2|Bacteria,1G1VY@1117|Cyanobacteria,1HM2T@1161|Nostocales	1117|Cyanobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_136040_1	313596.RB2501_05875	9.19e-101	306.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1HXA7@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_47930_1	1379698.RBG1_1C00001G1616	7.33e-19	93.6	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
k59_34437_1	1408473.JHXO01000006_gene1209	4.44e-105	325.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,2FWMX@200643|Bacteroidia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
k59_129213_1	1165841.SULAR_04217	3.18e-136	394.0	COG0477@1|root,COG2814@2|Bacteria,1R7DW@1224|Proteobacteria,43BJI@68525|delta/epsilon subdivisions,2YT98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_129213_2	1165841.SULAR_04212	5.28e-101	300.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115752_1	1123274.KB899406_gene1264	5.75e-12	64.7	COG0834@1|root,COG0834@2|Bacteria,2J7H4@203691|Spirochaetes	203691|Spirochaetes	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k59_115752_2	349521.HCH_05808	3.99e-60	197.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,1RN6V@1236|Gammaproteobacteria,1XIIE@135619|Oceanospirillales	135619|Oceanospirillales	P	amino acid ABC transporter	aapQ	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_142848_1	1454007.JAUG01000048_gene1946	3.18e-50	170.0	COG1708@1|root,COG1708@2|Bacteria,4NMIA@976|Bacteroidetes,1ISV1@117747|Sphingobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Adenyl_transf
k59_523_1	563040.Saut_1275	2.37e-33	131.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2YMPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Sulfatase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_7248_2	1165841.SULAR_01888	1.24e-06	48.9	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria	1224|Proteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	sdh	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_197148_1	582744.Msip34_1307	3.92e-106	318.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,2KMFN@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Putative methyltransferase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_176737_1	1173028.ANKO01000149_gene5570	3.17e-21	100.0	COG2911@1|root,COG2931@1|root,COG3210@1|root,COG5276@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Big_5,DUF4214,LVIVD,TIG
k59_190363_2	1165841.SULAR_09094	1.21e-171	488.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_210679_1	1122176.KB903587_gene4522	2.95e-55	195.0	COG0739@1|root,COG3291@1|root,COG0739@2|Bacteria,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1J0XQ@117747|Sphingobacteriia	976|Bacteroidetes	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_7260_1	748247.AZKH_4396	1.56e-16	83.6	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,2KUCW@206389|Rhodocyclales	206389|Rhodocyclales	E	Leucine-specific binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_61569_1	326298.Suden_1457	2.38e-72	228.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_183492_1	1123354.AUDR01000004_gene1576	8.23e-30	124.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2VJWM@28216|Betaproteobacteria,1KT7Y@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Na+/Pi-cotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
k59_197150_2	477641.MODMU_3299	5.28e-32	119.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4ESRK@85013|Frankiales	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_7263_1	1121904.ARBP01000017_gene5092	1.31e-46	158.0	28JHF@1|root,2Z9B0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142860_1	903818.KI912268_gene2829	5.29e-33	131.0	COG0784@1|root,COG1100@1|root,COG3852@1|root,COG0784@2|Bacteria,COG1100@2|Bacteria,COG3852@2|Bacteria,3Y9EH@57723|Acidobacteria	57723|Acidobacteria	T	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Ras,Response_reg
k59_20944_1	228410.NE2024	7.07e-63	195.0	COG3293@1|root,COG3293@2|Bacteria,1N8GF@1224|Proteobacteria,2WBR1@28216|Betaproteobacteria,373MQ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	InterPro IPR002559	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
k59_20944_2	94624.Bpet1403	6.72e-61	190.0	COG3293@1|root,COG3293@2|Bacteria,1N0VW@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
k59_14135_1	655815.ZPR_2447	4.66e-73	246.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_149617_1	338963.Pcar_0478	7.79e-43	152.0	COG4822@1|root,COG4822@2|Bacteria,1P36Y@1224|Proteobacteria,42P9C@68525|delta/epsilon subdivisions,2X2EP@28221|Deltaproteobacteria,43V04@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Cobalt chelatase (CbiK)	-	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
k59_149617_2	395493.BegalDRAFT_2883	7.97e-31	122.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,45ZW4@72273|Thiotrichales	72273|Thiotrichales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_190376_1	1121035.AUCH01000004_gene386	6.79e-25	105.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,2KWIE@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the bacterial glucokinase family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
k59_34462_1	1168034.FH5T_02880	1.15e-128	391.0	COG4206@1|root,COG4206@2|Bacteria,4PM79@976|Bacteroidetes	976|Bacteroidetes	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_34464_1	1123517.JOMR01000001_gene1732	1.71e-73	232.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,45ZYD@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_27695_1	984262.SGRA_1766	6.78e-17	79.7	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_27695_2	237368.SCABRO_00482	2.03e-45	160.0	COG0157@1|root,COG0157@2|Bacteria,2IYVV@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_183499_1	2340.JV46_11710	6.91e-104	303.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1J4K8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050	Sod_Fe_C,Sod_Fe_N
k59_169944_1	395493.BegalDRAFT_3104	1.82e-93	288.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,45ZY1@72273|Thiotrichales	72273|Thiotrichales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_163204_1	665029.EAMY_1759	7.72e-64	205.0	28PDP@1|root,2ZC5M@2|Bacteria,1RB40@1224|Proteobacteria,1S2HG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108958_1	1192034.CAP_4962	3.83e-51	175.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WIYY@28221|Deltaproteobacteria,2YWP3@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_81919_1	1165841.SULAR_06323	1.45e-49	159.0	COG0745@1|root,COG0745@2|Bacteria,1NEVF@1224|Proteobacteria,43C0G@68525|delta/epsilon subdivisions,2YTED@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413,ko:K07814	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_81919_2	1165841.SULAR_06318	1.93e-25	105.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_149633_1	113395.AXAI01000002_gene5540	3.12e-68	216.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,3JQMM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_61572_1	420324.KI912087_gene7237	7.16e-62	207.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria	1224|Proteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc
k59_27699_1	761193.Runsl_4104	6.69e-08	55.1	COG0454@1|root,COG0456@2|Bacteria,4NSKZ@976|Bacteroidetes,47QVA@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_27699_2	1249997.JHZW01000001_gene3975	1.49e-29	105.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia,2PHN6@252356|Maribacter	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_550_1	5808.XP_002141770.1	1.18e-06	57.0	KOG0605@1|root,KOG0605@2759|Eukaryota,3YBH7@5794|Apicomplexa,3YK9R@5796|Coccidia	5794|Apicomplexa	T	Serine/Threonine protein kinases, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_176757_1	1206558.I7K2T5_9CAUD	7.73e-06	53.9	4QBG4@10239|Viruses,4QUZA@35237|dsDNA viruses  no RNA stage,4QRSK@28883|Caudovirales,4QJW4@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_88696_2	1382356.JQMP01000004_gene562	7.25e-15	71.6	COG0718@1|root,COG0718@2|Bacteria,2G77S@200795|Chloroflexi,27YNT@189775|Thermomicrobia	189775|Thermomicrobia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_88696_3	1123278.KB893444_gene1688	2.56e-14	71.2	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,47JZK@768503|Cytophagia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_14148_2	1125863.JAFN01000001_gene1352	0.000542	42.4	COG0043@1|root,COG0043@2|Bacteria,1PZMY@1224|Proteobacteria,42RNW@68525|delta/epsilon subdivisions,2WNJN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
k59_190386_1	1545915.JROG01000004_gene2223	9.85e-83	256.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2K02R@204457|Sphingomonadales	204457|Sphingomonadales	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_7580_1	1123514.KB905899_gene1658	5.26e-43	156.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,460U9@72273|Thiotrichales	72273|Thiotrichales	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_136425_1	983920.Y88_2738	1.06e-60	202.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_48376_1	909663.KI867150_gene2054	1.64e-17	79.7	COG2836@1|root,COG2836@2|Bacteria,1QVGG@1224|Proteobacteria,432GS@68525|delta/epsilon subdivisions,2WXZW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
k59_136426_1	639282.DEFDS_2068	1.06e-54	187.0	COG0747@1|root,COG0747@2|Bacteria,2GEIN@200930|Deferribacteres	2|Bacteria	E	Peptide nickel ABC transporter, substrate-binding protein	dppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363	-	ko:K02035,ko:K12368,ko:K19226	ko01503,ko02010,ko02024,ko02030,map01503,map02010,map02024,map02030	M00239,M00324,M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.5	-	iSSON_1240.SSON_3846	SBP_bac_5
k59_122898_1	1165841.SULAR_04417	2.99e-75	241.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2YMEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_122898_2	1165841.SULAR_04422	2.36e-69	213.0	2AJKY@1|root,31A84@2|Bacteria,1Q53J@1224|Proteobacteria,430GT@68525|delta/epsilon subdivisions,2YRZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_28084_1	395493.BegalDRAFT_0364	2.8e-92	282.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,45ZTA@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_193781_1	1121012.AUKX01000006_gene324	1.21e-103	302.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1HYH3@117743|Flavobacteriia,23H1M@178469|Arenibacter	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_193781_2	313596.RB2501_08245	2.04e-45	154.0	2C0PB@1|root,331E0@2|Bacteria,4NUMG@976|Bacteroidetes,1I58I@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132876_1	879212.DespoDRAFT_00831	6.23e-162	490.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_139449_1	392499.Swit_1330	6.03e-43	151.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,2K25I@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_78464_1	2340.JV46_23730	6.07e-100	315.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1J4T4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_119407_1	1131730.BAVI_04554	4.54e-16	82.8	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1UEIC@1239|Firmicutes,4HDD8@91061|Bacilli,1ZAQA@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_4102_1	1165841.SULAR_09659	9.1e-110	338.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_17498_1	59196.RICGR_1476	2.09e-30	120.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1JCMP@118969|Legionellales	118969|Legionellales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_17498_2	318161.Sden_0002	4.54e-18	83.6	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,2Q9B7@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_179933_1	1268068.PG5_31440	2.39e-41	149.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	found to be peripherally associated with the inner membrane in Escherichia coli	trkA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iE2348C_1286.E2348C_3552	TrkA_C,TrkA_N
k59_139451_2	314285.KT71_05412	1.1e-48	169.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1J8C2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_10603_1	401053.AciPR4_1875	2.98e-59	200.0	COG0621@1|root,COG0621@2|Bacteria,3Y2GT@57723|Acidobacteria,2JIEP@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_44354_1	765912.Thimo_1294	1.26e-62	207.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1WW58@135613|Chromatiales	135613|Chromatiales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_44354_2	870187.Thini_3223	3.52e-38	129.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,463H7@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
k59_132883_1	679937.Bcop_1583	2.65e-68	218.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,2FMQH@200643|Bacteroidia,4AKP1@815|Bacteroidaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score 8.96	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
k59_179936_1	686578.AFFX01000003_gene44	7.28e-21	92.8	COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1MV41@1224|Proteobacteria,1RMPJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,Putative_PNPOx
k59_179936_2	398578.Daci_3323	6.63e-36	129.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,2VQER@28216|Betaproteobacteria,4AEJB@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Glutathione S-transferase domain	gst7	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
k59_71623_1	393921.HQ45_09300	1.72e-43	157.0	COG0436@1|root,COG0436@2|Bacteria,4NHP7@976|Bacteroidetes,2FN3D@200643|Bacteroidia,22XCE@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminotransferase	alaC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_10606_1	1173028.ANKO01000006_gene2079	9.26e-36	140.0	COG1262@1|root,COG1262@2|Bacteria,1GQW8@1117|Cyanobacteria,1H81P@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TPR_1,TPR_8
k59_58147_1	203122.Sde_2049	1.04e-45	168.0	COG5184@1|root,COG5276@1|root,COG5644@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5644@2|Bacteria,1QX03@1224|Proteobacteria,1T31Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
k59_153109_1	929558.SMGD1_1143	1.7e-10	60.1	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,42R2I@68525|delta/epsilon subdivisions,2YP1Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_153109_2	1165841.SULAR_04627	2.37e-63	196.0	COG0607@1|root,COG0607@2|Bacteria,1R70B@1224|Proteobacteria,42UX5@68525|delta/epsilon subdivisions,2YPT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_37512_2	1117315.AHCA01000013_gene3810	1.36e-42	141.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,2Q2QC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	COG1544 Ribosome-associated protein Y (PSrp-1)	yhbH	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_37512_3	999141.GME_03537	1.7e-31	121.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XH8A@135619|Oceanospirillales	135619|Oceanospirillales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_44360_1	497964.CfE428DRAFT_6315	1.99e-97	298.0	COG3356@1|root,COG3356@2|Bacteria,46TDV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
k59_179944_1	395493.BegalDRAFT_0016	2.04e-90	290.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,45ZMI@72273|Thiotrichales	72273|Thiotrichales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_17512_1	1165841.SULAR_08327	5.04e-94	279.0	COG0388@1|root,COG0388@2|Bacteria,1PZZZ@1224|Proteobacteria,42REP@68525|delta/epsilon subdivisions,2YP77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_51363_1	395493.BegalDRAFT_2260	5.47e-31	125.0	COG1361@1|root,COG2373@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,Cadherin_3,Calx-beta,FecR,PKD,SdrD_B,TGFb_propeptide
k59_31128_3	1165841.SULAR_00965	1.6e-11	61.2	2EKI4@1|root,33E83@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_105766_1	391615.ABSJ01000054_gene1390	1.33e-99	317.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1J4DR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_44364_1	994479.GL877878_gene1273	1.18e-23	92.4	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4EE5S@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thioredoxin	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
k59_44364_2	768671.ThimaDRAFT_0724	5.03e-35	119.0	2C7TU@1|root,32RJT@2|Bacteria,1N2CD@1224|Proteobacteria,1S96C@1236|Gammaproteobacteria,1WYZ5@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213914_1	1168034.FH5T_18410	4.47e-33	117.0	COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	mmdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
k59_213914_2	1168034.FH5T_18415	9.15e-51	164.0	COG3630@1|root,COG3630@2|Bacteria,4NV8J@976|Bacteroidetes,2G2DV@200643|Bacteroidia	976|Bacteroidetes	C	COG NOG19100 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	LTD,OAD_gamma
k59_112158_1	177437.HRM2_44660	3.36e-47	167.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,43AFH@68525|delta/epsilon subdivisions,2X5V7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_71632_1	2074.JNYD01000052_gene1551	1.68e-62	211.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4EAD5@85010|Pseudonocardiales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_85449_1	1499967.BAYZ01000045_gene2657	1.79e-16	79.3	COG1420@1|root,COG1420@2|Bacteria,2NPAK@2323|unclassified Bacteria	2|Bacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA,HrcA_DNA-bdg
k59_85449_2	927704.SELR_03770	0.00021	46.6	COG0859@1|root,COG0859@2|Bacteria,1UZZI@1239|Firmicutes,4H2VC@909932|Negativicutes	909932|Negativicutes	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_139474_1	1129794.C427_4186	4.91e-24	105.0	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1SYZR@1236|Gammaproteobacteria,466JZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
k59_186865_1	1165841.SULAR_05718	5.96e-78	236.0	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_24197_1	395493.BegalDRAFT_0076	1.73e-84	261.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S1WE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_125967_1	580332.Slit_2117	7.47e-82	257.0	COG0475@1|root,COG0475@2|Bacteria,1PK6U@1224|Proteobacteria,2WAEY@28216|Betaproteobacteria,44WJS@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_17529_2	2340.JV46_27230	5.87e-77	243.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1J4Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_153121_1	1165841.SULAR_09924	1.52e-102	303.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2YM8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_64888_1	118161.KB235922_gene3433	0.000668	42.4	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	2.1.1.72	ko:K07316,ko:K07495	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DDE_5,DDE_Tnp_1
k59_139481_1	933262.AXAM01000053_gene2713	6.89e-107	327.0	COG4770@1|root,COG5016@1|root,COG4770@2|Bacteria,COG5016@2|Bacteria,1P6RE@1224|Proteobacteria,43BQE@68525|delta/epsilon subdivisions,2X71H@28221|Deltaproteobacteria,2MHKV@213118|Desulfobacterales	28221|Deltaproteobacteria	CI	Conserved carboxylase domain	-	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_58171_1	1336249.JADW01000004_gene3542	1.55e-15	75.1	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2TSGN@28211|Alphaproteobacteria,4B8AV@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type sugar transport systems, permease components	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
k59_58171_2	1499967.BAYZ01000019_gene6305	2.03e-38	139.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	ugpB	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_8
k59_146437_1	373994.Riv7116_5516	1.22e-138	410.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria,1HRE0@1161|Nostocales	1117|Cyanobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_85457_1	90813.JQMT01000001_gene1669	8.24e-213	592.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,463S8@72273|Thiotrichales	72273|Thiotrichales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_51384_1	313596.RB2501_11627	4.25e-79	258.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1HZCQ@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_105783_1	1340493.JNIF01000003_gene3002	2.52e-38	145.0	COG1228@1|root,COG1228@2|Bacteria,3Y6WV@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_132918_1	1206545.S6CLR1_9CAUD	2.07e-27	122.0	4QEE7@10239|Viruses,4QV59@35237|dsDNA viruses  no RNA stage,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae	10662|Myoviridae	S	Pfam:DUF4815	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_153132_1	571.MC52_01580	2.68e-20	90.5	COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,1S2SY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	5'-deoxynucleotidase activity	yfdR	GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897	-	ko:K06952	-	-	-	-	ko00000	-	-	-	-
k59_17962_1	1249627.D779_3720	3.9e-05	46.6	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1WXBJ@135613|Chromatiales	135613|Chromatiales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_17962_2	1049564.TevJSym_af00240	8.48e-46	165.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1J4HR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S16 family	ycbZ	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_194159_2	1304888.ATWF01000001_gene704	2.02e-41	152.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_85841_1	631362.Thi970DRAFT_04327	3.96e-64	207.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1WWM6@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_72029_1	345073.VC395_2372	1.63e-76	237.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1XTBC@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	GO:0000270,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_146824_1	1004149.AFOE01000042_gene2698	1.71e-89	293.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_200840_1	1121459.AQXE01000002_gene1288	2.72e-37	141.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_17971_1	1229205.BUPH_04033	2.03e-41	150.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,1K3FH@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_65303_1	1125863.JAFN01000001_gene1256	4.89e-76	243.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,43BD6@68525|delta/epsilon subdivisions,2X6S2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_126347_1	563040.Saut_0079	2.93e-62	198.0	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_146838_1	1165841.SULAR_02673	1.44e-64	208.0	COG3400@1|root,COG3400@2|Bacteria,1N5T1@1224|Proteobacteria,42M0B@68525|delta/epsilon subdivisions,2YMCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	domain protein	-	-	-	ko:K09944	-	-	-	-	ko00000	-	-	-	TrkA_C
k59_146838_2	1165841.SULAR_02668	2.1e-18	82.8	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_99451_1	983545.Glaag_1018	1.36e-55	182.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,46D3A@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_85849_1	1165841.SULAR_09894	1.24e-100	296.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_109644_2	926562.Oweho_1283	4.55e-55	179.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HZ28@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
k59_150295_1	765913.ThidrDRAFT_0772	7.65e-96	297.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales	135613|Chromatiales	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_211449_1	58123.JOFJ01000014_gene5179	6.46e-05	50.8	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4EHMT@85012|Streptosporangiales	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_14806_1	886293.Sinac_6266	2.49e-41	150.0	2DMFF@1|root,32R5F@2|Bacteria	2|Bacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_96098_1	1165841.SULAR_06713	2.19e-79	241.0	COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,42PSA@68525|delta/epsilon subdivisions,2YNHW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
k59_41802_1	485918.Cpin_2434	2.79e-25	109.0	COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,1IQVI@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_68919_1	4081.Solyc00g049210.1.1	5.52e-204	577.0	COG1138@1|root,2QQ5D@2759|Eukaryota,37KAN@33090|Viridiplantae,3G7VB@35493|Streptophyta	35493|Streptophyta	O	cytochrome c	ccmFN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0017004,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_62220_1	5145.XP_001905626.1	7.63e-15	79.0	2CUUE@1|root,2RP86@2759|Eukaryota,39Y0B@33154|Opisthokonta,3NXSE@4751|Fungi,3QPMD@4890|Ascomycota,21C7G@147550|Sordariomycetes	4751|Fungi	E	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Astacin,H_lectin,Peptidase_M10
k59_177347_1	1121403.AUCV01000001_gene925	2.4e-28	110.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,42S1K@68525|delta/epsilon subdivisions,2WP14@28221|Deltaproteobacteria,2MK1H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
k59_55441_2	2340.JV46_07380	2.45e-60	186.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1JAM7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_55441_3	519989.ECTPHS_13058	4.38e-107	313.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1WVZS@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_55441_4	2340.JV46_07360	2.08e-20	85.9	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1J4YN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_116532_1	888062.HMPREF9083_1232	1.1e-29	121.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4H34H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_129921_1	563040.Saut_1599	3.66e-12	71.2	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_129921_2	1121342.AUCO01000004_gene575	4.73e-48	167.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,36ECS@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_21500_1	1121468.AUBR01000027_gene2885	4.66e-07	56.2	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,42FT9@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM sporulation protein, yteA	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
k59_62224_1	903818.KI912268_gene923	4.55e-65	223.0	COG0209@1|root,COG0209@2|Bacteria,3Y3Q1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
k59_62228_1	1123320.KB889703_gene9424	2.21e-24	106.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_177355_1	1165841.SULAR_09089	1.36e-53	179.0	COG0642@1|root,COG2205@2|Bacteria,1QZF7@1224|Proteobacteria,43CIH@68525|delta/epsilon subdivisions,2YTD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_136718_2	1266925.JHVX01000014_gene1574	3.45e-61	199.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,3727J@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Aminotransferase, class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_28413_1	3880.AES69829	1.62e-104	325.0	COG0048@1|root,COG0049@1|root,COG1007@1|root,KOG1750@2759|Eukaryota,KOG3291@2759|Eukaryota,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,4JNJF@91835|fabids	35493|Streptophyta	C	NAD(P)H-quinone oxidoreductase subunit 2	ndhB	-	1.6.5.3	ko:K02992,ko:K05573	ko00190,ko01100,ko03010,map00190,map01100,map03010	M00145,M00178,M00179	R11945	RC00061	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	Proton_antipo_M
k59_14814_2	1304885.AUEY01000046_gene11	2.76e-19	86.7	COG2172@1|root,COG2172@2|Bacteria,1Q2UT@1224|Proteobacteria,42V6B@68525|delta/epsilon subdivisions,2WRJ9@28221|Deltaproteobacteria,2MKWV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	anti-sigma regulatory factor	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k59_102921_1	2340.JV46_17370	2.66e-60	193.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1J4Z2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
k59_163837_1	1165841.SULAR_03342	1.34e-107	322.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_48694_1	867900.Celly_0853	4.38e-08	55.1	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,1F8VG@104264|Cellulophaga	976|Bacteroidetes	H	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_48694_2	313596.RB2501_04110	5.78e-59	197.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_55456_1	444861.E3SPQ5_9CAUD	7.15e-12	68.9	4QCWD@10239|Viruses,4QUQN@35237|dsDNA viruses  no RNA stage,4QUCZ@28883|Caudovirales	28883|Caudovirales	S	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129930_1	998674.ATTE01000001_gene2740	1.15e-101	308.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales	72273|Thiotrichales	L	Exonuclease C-terminal	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k59_157078_1	1168034.FH5T_18820	4.53e-107	337.0	COG2887@1|root,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,2FN03@200643|Bacteroidia	976|Bacteroidetes	L	DNA-dependent ATPase I and helicase II	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_75676_1	3750.XP_008353911.1	3.91e-10	60.1	COG2801@1|root,KOG1339@1|root,KOG0017@2759|Eukaryota,KOG1339@2759|Eukaryota,37NAX@33090|Viridiplantae,3GB83@35493|Streptophyta,4JJHE@91835|fabids	35493|Streptophyta	O	Belongs to the peptidase A1 family	-	GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0016020,GO:0016787,GO:0019538,GO:0030163,GO:0031224,GO:0031225,GO:0031226,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046658,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K00924	-	-	-	-	ko00000,ko01000	-	-	-	TAXi_C,TAXi_N
k59_177357_1	886377.Murru_1388	6.64e-35	133.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1HXND@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
k59_177357_2	313596.RB2501_06580	9.3e-66	202.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_68931_2	941449.dsx2_2965	4.45e-13	65.1	COG2044@1|root,COG2044@2|Bacteria,1RIFN@1224|Proteobacteria,42UMB@68525|delta/epsilon subdivisions,2WQMD@28221|Deltaproteobacteria,2MD9S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM DsrE family protein	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_35043_1	1122609.AUGT01000009_gene3160	5.42e-106	314.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,4DP7C@85009|Propionibacteriales	201174|Actinobacteria	M	RmlD substrate binding domain	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_197863_1	1165841.SULAR_07178	1.32e-44	152.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2YMJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_109665_1	1049564.TevJSym_ac01950	2.21e-106	317.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1J4M5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_136731_1	102107.XP_008225561.1	0.000744	43.9	COG0531@1|root,KOG1286@2759|Eukaryota,37JF4@33090|Viridiplantae,3GFI1@35493|Streptophyta,4JMH1@91835|fabids	35493|Streptophyta	E	cationic amino acid transporter	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
k59_136731_2	1165841.SULAR_03262	8.46e-28	110.0	COG0465@1|root,COG0465@2|Bacteria,1NQVB@1224|Proteobacteria,42MWB@68525|delta/epsilon subdivisions,2YR9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_89461_1	4565.Traes_2AL_F52C84040.1	5.13e-35	124.0	COG0839@1|root,2S14H@2759|Eukaryota,389Z6@33090|Viridiplantae,3GX82@35493|Streptophyta,3MAU6@4447|Liliopsida	35493|Streptophyta	P	Belongs to the complex I subunit 6 family	NAD6	-	1.6.5.3	ko:K03884	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q3
k59_157534_1	1117647.M5M_18685	8.19e-94	285.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1J7R2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_15229_1	572480.Arnit_0211	3.79e-216	603.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_1689_1	1168034.FH5T_21205	1.11e-68	215.0	COG2227@1|root,COG2227@2|Bacteria,4PKW0@976|Bacteroidetes,2FNGZ@200643|Bacteroidia	976|Bacteroidetes	H	Methyltransferase domain protein	cypM_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_103332_1	1122201.AUAZ01000015_gene729	6.67e-80	250.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,46AEQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II/IV secretion system protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_123580_1	403833.Pmob_1479	1.93e-20	94.7	COG1219@1|root,COG1219@2|Bacteria,2GC9Y@200918|Thermotogae	200918|Thermotogae	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_150733_1	1168034.FH5T_19425	1.16e-26	108.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,2FQ2H@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
k59_8289_1	1220534.B655_0882	7.09e-92	278.0	COG0451@1|root,arCOG01376@2157|Archaea,2XVGW@28890|Euryarchaeota	28890|Euryarchaeota	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_157548_1	1056512.D515_02964	4.61e-31	126.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XZWD@135623|Vibrionales	135623|Vibrionales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_211845_1	864702.OsccyDRAFT_0410	3.57e-57	196.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_trans_1_2,Glyco_transf_9,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
k59_55880_1	1121405.dsmv_1723	1.62e-31	115.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,42SXV@68525|delta/epsilon subdivisions,2WPSN@28221|Deltaproteobacteria,2MK91@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
k59_55880_2	933262.AXAM01000010_gene1398	5.41e-10	59.7	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria,2MJWD@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_103341_1	2340.JV46_18890	7.7e-84	263.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1J7ED@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG1459 Type II secretory pathway, component PulF	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_117023_1	1168034.FH5T_05125	4.26e-119	348.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,2FNG4@200643|Bacteroidia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_184606_1	1500301.JQMF01000007_gene1582	1.22e-28	117.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,4B97V@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_21950_1	371731.Rsw2DRAFT_3304	2.7e-18	79.7	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2U6FZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_21950_2	987059.RBXJA2T_09282	2.02e-21	86.3	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,1KMF3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	sirA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k59_76094_1	95619.PM1_0213420	6.54e-78	240.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_177772_1	697282.Mettu_1700	3.67e-16	84.7	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales	1236|Gammaproteobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	2.7.13.3	ko:K07646,ko:K07679	ko02020,ko05133,map02020,map05133	M00454,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_89884_1	395493.BegalDRAFT_3269	2.79e-26	108.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,46035@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_62752_1	212042.APH_1119	2.34e-51	176.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,47G30@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_83155_1	1238190.AMQY01000010_gene2373	6.74e-40	144.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XHND@135619|Oceanospirillales	135619|Oceanospirillales	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_83155_2	32042.PstZobell_05788	1.35e-12	66.6	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1Z04F@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	colR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_164293_1	1545915.JROG01000004_gene2522	2.68e-12	68.6	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,2K1DA@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_146956_1	1121865.OMW_00187	2.02e-25	105.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,4AZX1@81852|Enterococcaceae	91061|Bacilli	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_166964_1	323261.Noc_2889	1.63e-29	116.0	COG0438@1|root,COG0438@2|Bacteria,1MVB4@1224|Proteobacteria,1RNYM@1236|Gammaproteobacteria,1WXPU@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_166964_2	243233.MCA2514	1.66e-12	66.2	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1XDR5@135618|Methylococcales	135618|Methylococcales	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_119889_1	395493.BegalDRAFT_2923	5.27e-100	322.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,461Q7@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_85975_2	631362.Thi970DRAFT_01234	1.6e-52	177.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1WX8S@135613|Chromatiales	135613|Chromatiales	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_4708_1	1121430.JMLG01000001_gene2338	3.93e-41	152.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,2605J@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R10149,R11487	RC00168,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_180510_1	7668.SPU_027102-tr	4.7e-38	146.0	2CMGD@1|root,2QQ9V@2759|Eukaryota,39B3J@33154|Opisthokonta,3BKG5@33208|Metazoa,3CTR5@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_2
k59_24738_1	28229.ND2E_0777	6.64e-20	88.6	COG0500@1|root,COG2226@2|Bacteria,1PDVU@1224|Proteobacteria,1RXQY@1236|Gammaproteobacteria,2Q853@267889|Colwelliaceae	1236|Gammaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_112553_1	1165841.SULAR_06318	1.49e-91	295.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_65463_1	927658.AJUM01000044_gene630	1.73e-19	93.2	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,2G2I0@200643|Bacteroidia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_160459_1	45351.EDO38587	3.93e-45	161.0	COG1053@1|root,KOG2403@2759|Eukaryota,38CSD@33154|Opisthokonta,3BAX6@33208|Metazoa	33208|Metazoa	C	anaerobic respiration	SDHA	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005749,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006119,GO:0006121,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0008177,GO:0009055,GO:0009060,GO:0009061,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016627,GO:0016635,GO:0016999,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045257,GO:0045273,GO:0045281,GO:0045283,GO:0045333,GO:0046034,GO:0046483,GO:0048731,GO:0048856,GO:0055086,GO:0055114,GO:0070013,GO:0070469,GO:0071704,GO:0072350,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.3.5.1	ko:K00234	ko00020,ko00190,ko01100,ko01110,ko01120,ko01130,ko01200,ko04714,ko04932,ko05010,ko05012,ko05016,map00020,map00190,map01100,map01110,map01120,map01130,map01200,map04714,map04932,map05010,map05012,map05016	M00009,M00011,M00148	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_180512_1	1165841.SULAR_08874	8.39e-91	280.0	COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,43DZE@68525|delta/epsilon subdivisions,2YRGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
k59_85984_1	1165841.SULAR_09204	3.54e-72	227.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_85984_2	1165841.SULAR_09199	1.28e-53	175.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2YMIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_44953_1	3750.XP_008387315.1	2.71e-22	97.4	COG2801@1|root,KOG1075@1|root,KOG0017@2759|Eukaryota,KOG1075@2759|Eukaryota,37Q53@33090|Viridiplantae,3GHAQ@35493|Streptophyta,4JSM9@91835|fabids	35493|Streptophyta	L	ribonuclease H protein At1g65750	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,RVT_1,RVT_3,zf-RVT
k59_44953_2	3827.XP_004516035.1	3.36e-17	82.8	COG2801@1|root,KOG0017@2759|Eukaryota,388SY@33090|Viridiplantae,3GND2@35493|Streptophyta	35493|Streptophyta	L	DNA RNA polymerases superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	RVP_2,Retrotrans_gag,zf-CCHC
k59_194313_1	1123400.KB904746_gene1153	1.41e-57	205.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_207923_1	2340.JV46_03430	2.73e-43	146.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_207923_2	631362.Thi970DRAFT_03095	1.37e-22	95.5	28T0P@1|root,2ZF9Z@2|Bacteria,1RAUV@1224|Proteobacteria,1S23D@1236|Gammaproteobacteria,1WY26@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_207923_3	323261.Noc_1810	5.51e-23	96.3	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria,1WW9W@135613|Chromatiales	135613|Chromatiales	S	PFAM 5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_44956_1	1198232.CYCME_0116	4.95e-83	254.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,45ZXE@72273|Thiotrichales	72273|Thiotrichales	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_65472_1	180332.JTGN01000004_gene2495	3e-57	191.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,24B8Y@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,CBM_6,F5_F8_type_C
k59_194316_1	1150474.JQJI01000022_gene671	1.29e-15	72.4	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_194316_2	742821.HMPREF9464_01431	1.99e-47	165.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,4PQ82@995019|Sutterellaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_78966_1	2340.JV46_20340	3.03e-86	276.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1J62R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_18149_1	292415.Tbd_0283	8.19e-32	121.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VJEB@28216|Betaproteobacteria	28216|Betaproteobacteria	D	AAA domain	yveL	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
k59_119909_1	396588.Tgr7_1579	2.69e-85	265.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_99553_1	686340.Metal_1029	1.87e-22	97.8	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XE56@135618|Methylococcales	135618|Methylococcales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	-
k59_207928_1	385682.AFSL01000053_gene487	7.79e-40	143.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,2FMKB@200643|Bacteroidia,3XITR@558415|Marinilabiliaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_106400_1	2340.JV46_08450	9.11e-60	190.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1JAU3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	probably involved in intracellular septation	ispZ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k59_106400_2	765913.ThidrDRAFT_3135	3.05e-25	102.0	28JN1@1|root,2Z9EG@2|Bacteria,1R8TZ@1224|Proteobacteria,1S1S0@1236|Gammaproteobacteria,1WXT2@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85996_1	1165841.SULAR_04172	3.64e-108	329.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_126899_1	1165841.SULAR_08472	1.01e-120	360.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42ZC0@68525|delta/epsilon subdivisions,2YR4G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_112841_2	1123511.KB905845_gene2904	4.48e-18	84.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4H4NK@909932|Negativicutes	909932|Negativicutes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_59101_1	1118153.MOY_11482	1.21e-24	102.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,1RQ47@1236|Gammaproteobacteria,1XPIC@135619|Oceanospirillales	135619|Oceanospirillales	P	Predicted Permease Membrane Region	-	-	-	-	-	-	-	-	-	-	-	-	Asp-Al_Ex,TrkA_C
k59_59101_2	755178.Cyan10605_0221	2.89e-54	182.0	COG0076@1|root,COG0076@2|Bacteria,1G47D@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the group II decarboxylase family	gad	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
k59_194751_1	1165841.SULAR_06303	5.35e-30	117.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_194751_2	1165841.SULAR_06298	3.71e-82	245.0	2ARMJ@1|root,31GY7@2|Bacteria,1QEMQ@1224|Proteobacteria,42VV2@68525|delta/epsilon subdivisions,2YQ9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_126902_1	349966.DJ58_1131	1.37e-139	423.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,41G00@629|Yersinia	1236|Gammaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoR124_C,HSDR_N,ResIII
k59_93118_1	1123073.KB899242_gene1693	2.14e-06	48.1	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1X6HE@135614|Xanthomonadales	135614|Xanthomonadales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_59104_1	387093.SUN_0633	1.7e-74	248.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_45443_1	864051.BurJ1DRAFT_0701	1.33e-35	124.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,1KKVP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Lactoylglutathione lyase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_45443_2	933262.AXAM01000046_gene140	4.07e-32	124.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2MI0S@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
k59_174219_1	1121937.AUHJ01000019_gene1302	1.14e-07	52.8	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,464V7@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_59109_1	1123399.AQVE01000005_gene1023	6.75e-65	214.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,4602P@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_65899_1	1519464.HY22_06225	4.32e-07	53.1	2DBYH@1|root,2ZBV5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_112854_2	1165841.SULAR_09909	1.36e-42	148.0	COG2863@1|root,COG2863@2|Bacteria,1Q3W8@1224|Proteobacteria,42XWZ@68525|delta/epsilon subdivisions,2YQX6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_112854_3	1165841.SULAR_09904	2.58e-17	80.5	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_38285_1	309807.SRU_2403	2.33e-20	90.9	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,1FJUD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_38285_2	1121403.AUCV01000004_gene2039	1.68e-89	266.0	COG1853@1|root,COG1853@2|Bacteria,1RBSR@1224|Proteobacteria,42R0G@68525|delta/epsilon subdivisions,2WMYE@28221|Deltaproteobacteria,2MJGX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_140266_1	1205908.AKXW01000005_gene3320	2.35e-23	103.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,1XTRP@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_79405_1	1535422.ND16A_2918	7.19e-08	52.8	2DS06@1|root,33DXP@2|Bacteria,1NJMQ@1224|Proteobacteria,1SJ5T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79405_2	999425.HMPREF9186_00942	1.58e-48	159.0	COG4283@1|root,COG4283@2|Bacteria,1V8M5@1239|Firmicutes	1239|Firmicutes	S	cog cog4283	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
k59_174232_1	387093.SUN_1365	1.74e-21	91.3	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_174232_2	1165841.SULAR_00835	2.17e-90	267.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,42RIW@68525|delta/epsilon subdivisions,2YP6Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane-associated protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_93138_3	1121438.JNJA01000021_gene1362	1.14e-18	86.3	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,42NMN@68525|delta/epsilon subdivisions,2WJJH@28221|Deltaproteobacteria,2MBJ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	TIGRFAM Phage shock protein A	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k59_201387_1	313603.FB2170_02560	4.72e-64	209.0	COG0526@1|root,COG0526@2|Bacteria,4PMBW@976|Bacteroidetes,1IJR4@117743|Flavobacteriia,2PGKV@252356|Maribacter	976|Bacteroidetes	CO	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
k59_79406_1	945550.VISI1226_22680	7.85e-42	156.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XT1B@135623|Vibrionales	135623|Vibrionales	CI	oxaloacetate	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_72661_1	2340.JV46_10150	1.08e-33	121.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_72661_2	2340.JV46_10160	2.94e-25	94.7	COG4736@1|root,COG4736@2|Bacteria,1QEFV@1224|Proteobacteria,1TB54@1236|Gammaproteobacteria,1J781@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG4736 Cbb3-type cytochrome oxidase, subunit 3	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_72661_3	375286.mma_1634	3.52e-26	105.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4726F@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_59120_1	870187.Thini_1819	5.76e-37	136.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,4628N@72273|Thiotrichales	72273|Thiotrichales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
k59_59120_2	1123257.AUFV01000008_gene705	1.72e-35	132.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1X3PK@135614|Xanthomonadales	135614|Xanthomonadales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_18522_1	391587.KAOT1_06162	1.16e-66	217.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_112860_1	519989.ECTPHS_02901	1.69e-22	97.1	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	ygaU	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0030955,GO:0031420,GO:0035864,GO:0040008,GO:0040009,GO:0040010,GO:0042221,GO:0043167,GO:0043169,GO:0045927,GO:0046872,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007	-	ko:K21687,ko:K21688,ko:K21689,ko:K21690,ko:K21691	-	-	-	-	ko00000	-	GH23	-	LysM,Peptidase_M23,Transglycosylas
k59_187805_1	1165841.SULAR_05898	1.25e-111	351.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_201397_1	522306.CAP2UW1_3091	1.53e-40	152.0	COG1262@1|root,COG1262@2|Bacteria,1PWQN@1224|Proteobacteria,2W0G0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_214674_1	28072.Nos7524_2347	1.78e-86	268.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1G21B@1117|Cyanobacteria,1HKHB@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_18524_1	387093.SUN_1761	6.43e-89	267.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2YNFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
## 6877 queries scanned
## Total time (seconds): 93.2879285812378
## Rate: 73.72 q/s